id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-103536-etin5i7y	Timmins, Joanna	Structural studies on the Ebola virus matrix protein VP40 indicate that matrix proteins of enveloped RNA viruses are analogues but not homologues	2004-04-15		.txt	text/plain	4273	217	46	Although in some cases matrix protein expression in eukaryotic cells is sufficient to induce virus-like particles (VLPs) [3] [4] [5] , the structural requirements for such ordered membrane-associated polymerisation reactions are not well understood and often depend on other viral components such as the glycoprotein [2] . Like the matrix protein from negative strand RNA viruses MA is associated with the viral membrane and thus performs essentially the same structural function [6] . The first evidence for the involvement of specific Gag domains in viral budding came from the work of G€ ottlinger and colleagues who reported that a deletion of the C-terminal region of HIV Gag (p6 protein) caused a significant defect in virus particle release [8] . A minimal structural conservation is the presence of late domain sequences that mediate interaction with the class E Vps machinery for budding, although this still has to be shown in case of influenza virus M1.	./cache/cord-103536-etin5i7y.txt	./txt/cord-103536-etin5i7y.txt