id	sid	tid	token	lemma	pos
cord-104223-ht3ry9i0	1	1	key	key	JJ
cord-104223-ht3ry9i0	1	2	:	:	:
cord-104223-ht3ry9i0	1	3	cord-104223-ht3ry9i0	cord-104223-ht3ry9i0	JJ
cord-104223-ht3ry9i0	1	4	authors	author	NNS
cord-104223-ht3ry9i0	1	5	:	:	:
cord-104223-ht3ry9i0	2	1	nan	nan	NNP
cord-104223-ht3ry9i0	2	2	title	title	NN
cord-104223-ht3ry9i0	2	3	:	:	:
cord-104223-ht3ry9i0	3	1	Sorting	sort	VBG
cord-104223-ht3ry9i0	3	2	within	within	IN
cord-104223-ht3ry9i0	3	3	the	the	DT
cord-104223-ht3ry9i0	3	4	regulated	regulate	VBN
cord-104223-ht3ry9i0	3	5	secretory	secretory	JJ
cord-104223-ht3ry9i0	3	6	pathway	pathway	NN
cord-104223-ht3ry9i0	3	7	occurs	occur	VBZ
cord-104223-ht3ry9i0	3	8	in	in	IN
cord-104223-ht3ry9i0	3	9	the	the	DT
cord-104223-ht3ry9i0	3	10	trans-	trans-	JJ
cord-104223-ht3ry9i0	3	11	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	3	12	network	network	NN
cord-104223-ht3ry9i0	3	13	date	date	NN
cord-104223-ht3ry9i0	3	14	:	:	:
cord-104223-ht3ry9i0	3	15	1990	1990	CD
cord-104223-ht3ry9i0	3	16	-	-	SYM
cord-104223-ht3ry9i0	3	17	01	01	CD
cord-104223-ht3ry9i0	3	18	-	-	HYPH
cord-104223-ht3ry9i0	3	19	01	01	CD
cord-104223-ht3ry9i0	3	20	journal	journal	NN
cord-104223-ht3ry9i0	3	21	:	:	:
cord-104223-ht3ry9i0	4	1	J	J	NNP
cord-104223-ht3ry9i0	4	2	Cell	Cell	NNP
cord-104223-ht3ry9i0	4	3	Biol	Biol	NNP
cord-104223-ht3ry9i0	4	4	DOI	DOI	NNP
cord-104223-ht3ry9i0	4	5	:	:	:
cord-104223-ht3ry9i0	4	6	nan	nan	NNP
cord-104223-ht3ry9i0	4	7	sha	sha	NNP
cord-104223-ht3ry9i0	4	8	:	:	:
cord-104223-ht3ry9i0	5	1	26b944ce8d2f033704c7aeef38b0c128c0dd18be	26b944ce8d2f033704c7aeef38b0c128c0dd18be	CD
cord-104223-ht3ry9i0	5	2	doc_id	doc_id	CD
cord-104223-ht3ry9i0	5	3	:	:	:
cord-104223-ht3ry9i0	5	4	104223	104223	CD
cord-104223-ht3ry9i0	5	5	cord_uid	cord_uid	NNS
cord-104223-ht3ry9i0	5	6	:	:	:
cord-104223-ht3ry9i0	6	1	ht3ry9i0	ht3ry9i0	XX
cord-104223-ht3ry9i0	7	1	Bioactive	bioactive	JJ
cord-104223-ht3ry9i0	7	2	peptides	peptide	NNS
cord-104223-ht3ry9i0	7	3	cleaved	cleave	VBN
cord-104223-ht3ry9i0	7	4	from	from	IN
cord-104223-ht3ry9i0	7	5	the	the	DT
cord-104223-ht3ry9i0	7	6	egg	egg	NN
cord-104223-ht3ry9i0	7	7	-	-	HYPH
cord-104223-ht3ry9i0	7	8	laying	lay	VBG
cord-104223-ht3ry9i0	7	9	hormone	hormone	NN
cord-104223-ht3ry9i0	7	10	precursor	precursor	NN
cord-104223-ht3ry9i0	7	11	in	in	IN
cord-104223-ht3ry9i0	7	12	the	the	DT
cord-104223-ht3ry9i0	7	13	bag	bag	NN
cord-104223-ht3ry9i0	7	14	cell	cell	NN
cord-104223-ht3ry9i0	7	15	neurons	neuron	NNS
cord-104223-ht3ry9i0	7	16	of	of	IN
cord-104223-ht3ry9i0	7	17	Aplysia	Aplysia	NNP
cord-104223-ht3ry9i0	7	18	are	be	VBP
cord-104223-ht3ry9i0	7	19	sorted	sort	VBN
cord-104223-ht3ry9i0	7	20	into	into	IN
cord-104223-ht3ry9i0	7	21	distinct	distinct	JJ
cord-104223-ht3ry9i0	7	22	dense	dense	JJ
cord-104223-ht3ry9i0	7	23	core	core	NN
cord-104223-ht3ry9i0	7	24	vesicle	vesicle	NN
cord-104223-ht3ry9i0	7	25	classes	class	NNS
cord-104223-ht3ry9i0	7	26	(	(	-LRB-
cord-104223-ht3ry9i0	7	27	DCVs	dcv	NNS
cord-104223-ht3ry9i0	7	28	)	)	-RRB-
cord-104223-ht3ry9i0	7	29	.	.	.
cord-104223-ht3ry9i0	8	1	Bag	bag	NN
cord-104223-ht3ry9i0	8	2	cell	cell	NN
cord-104223-ht3ry9i0	8	3	prohormone	prohormone	NN
cord-104223-ht3ry9i0	8	4	processing	processing	NN
cord-104223-ht3ry9i0	8	5	can	can	MD
cord-104223-ht3ry9i0	8	6	be	be	VB
cord-104223-ht3ry9i0	8	7	divided	divide	VBN
cord-104223-ht3ry9i0	8	8	into	into	IN
cord-104223-ht3ry9i0	8	9	two	two	CD
cord-104223-ht3ry9i0	8	10	stages	stage	NNS
cord-104223-ht3ry9i0	8	11	,	,	,
cord-104223-ht3ry9i0	8	12	an	an	DT
cord-104223-ht3ry9i0	8	13	initial	initial	JJ
cord-104223-ht3ry9i0	8	14	cleavage	cleavage	NN
cord-104223-ht3ry9i0	8	15	occurring	occur	VBG
cord-104223-ht3ry9i0	8	16	in	in	IN
cord-104223-ht3ry9i0	8	17	a	a	DT
cord-104223-ht3ry9i0	8	18	late	late	JJ
cord-104223-ht3ry9i0	8	19	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	8	20	compartment	compartment	NN
cord-104223-ht3ry9i0	8	21	,	,	,
cord-104223-ht3ry9i0	8	22	which	which	WDT
cord-104223-ht3ry9i0	8	23	is	be	VBZ
cord-104223-ht3ry9i0	8	24	not	not	RB
cord-104223-ht3ry9i0	8	25	blocked	block	VBN
cord-104223-ht3ry9i0	8	26	by	by	IN
cord-104223-ht3ry9i0	8	27	monensin	monensin	NNP
cord-104223-ht3ry9i0	8	28	,	,	,
cord-104223-ht3ry9i0	8	29	and	and	CC
cord-104223-ht3ry9i0	8	30	later	later	JJ
cord-104223-ht3ry9i0	8	31	cleavages	cleavage	NNS
cord-104223-ht3ry9i0	8	32	that	that	WDT
cord-104223-ht3ry9i0	8	33	occur	occur	VBP
cord-104223-ht3ry9i0	8	34	within	within	IN
cord-104223-ht3ry9i0	8	35	DCVs	dcv	NNS
cord-104223-ht3ry9i0	8	36	and	and	CC
cord-104223-ht3ry9i0	8	37	are	be	VBP
cord-104223-ht3ry9i0	8	38	blocked	block	VBN
cord-104223-ht3ry9i0	8	39	by	by	IN
cord-104223-ht3ry9i0	8	40	monensin	monensin	NNP
cord-104223-ht3ry9i0	8	41	.	.	.
cord-104223-ht3ry9i0	9	1	Prohormone	Prohormone	NNP
cord-104223-ht3ry9i0	9	2	intermediates	intermediate	NNS
cord-104223-ht3ry9i0	9	3	are	be	VBP
cord-104223-ht3ry9i0	9	4	sorted	sort	VBN
cord-104223-ht3ry9i0	9	5	in	in	IN
cord-104223-ht3ry9i0	9	6	the	the	DT
cord-104223-ht3ry9i0	9	7	trans	trans	NNP
cord-104223-ht3ry9i0	9	8	-	-	NNP
cord-104223-ht3ry9i0	9	9	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	9	10	network	network	NN
cord-104223-ht3ry9i0	9	11	.	.	.
cord-104223-ht3ry9i0	10	1	The	the	DT
cord-104223-ht3ry9i0	10	2	large	large	JJ
cord-104223-ht3ry9i0	10	3	soma	soma	NN
cord-104223-ht3ry9i0	10	4	-	-	HYPH
cord-104223-ht3ry9i0	10	5	specific	specific	JJ
cord-104223-ht3ry9i0	10	6	DCVs	dcv	NNS
cord-104223-ht3ry9i0	10	7	turn	turn	VB
cord-104223-ht3ry9i0	10	8	over	over	RP
cord-104223-ht3ry9i0	10	9	,	,	,
cord-104223-ht3ry9i0	10	10	while	while	IN
cord-104223-ht3ry9i0	10	11	the	the	DT
cord-104223-ht3ry9i0	10	12	small	small	JJ
cord-104223-ht3ry9i0	10	13	DCVs	dcv	NNS
cord-104223-ht3ry9i0	10	14	are	be	VBP
cord-104223-ht3ry9i0	10	15	transported	transport	VBN
cord-104223-ht3ry9i0	10	16	to	to	IN
cord-104223-ht3ry9i0	10	17	processes	process	NNS
cord-104223-ht3ry9i0	10	18	for	for	IN
cord-104223-ht3ry9i0	10	19	regulated	regulated	JJ
cord-104223-ht3ry9i0	10	20	release	release	NN
cord-104223-ht3ry9i0	10	21	.	.	.
cord-104223-ht3ry9i0	11	1	Thus	thus	RB
cord-104223-ht3ry9i0	11	2	,	,	,
cord-104223-ht3ry9i0	11	3	protein	protein	NN
cord-104223-ht3ry9i0	11	4	trafficking	trafficking	NN
cord-104223-ht3ry9i0	11	5	differentially	differentially	RB
cord-104223-ht3ry9i0	11	6	regulates	regulate	VBZ
cord-104223-ht3ry9i0	11	7	the	the	DT
cord-104223-ht3ry9i0	11	8	levels	level	NNS
cord-104223-ht3ry9i0	11	9	and	and	CC
cord-104223-ht3ry9i0	11	10	localization	localization	NN
cord-104223-ht3ry9i0	11	11	of	of	IN
cord-104223-ht3ry9i0	11	12	multiple	multiple	JJ
cord-104223-ht3ry9i0	11	13	biologically	biologically	RB
cord-104223-ht3ry9i0	11	14	active	active	JJ
cord-104223-ht3ry9i0	11	15	peptides	peptide	NNS
cord-104223-ht3ry9i0	11	16	derived	derive	VBN
cord-104223-ht3ry9i0	11	17	from	from	IN
cord-104223-ht3ry9i0	11	18	a	a	DT
cord-104223-ht3ry9i0	11	19	common	common	JJ
cord-104223-ht3ry9i0	11	20	prohormone	prohormone	NN
cord-104223-ht3ry9i0	11	21	.	.	.
cord-104223-ht3ry9i0	12	1	1	1	LS
cord-104223-ht3ry9i0	12	2	.	.	.
cord-104223-ht3ry9i0	13	1	Abbreviations	abbreviation	NNS
cord-104223-ht3ry9i0	13	2	used	use	VBN
cord-104223-ht3ry9i0	13	3	in	in	IN
cord-104223-ht3ry9i0	13	4	thispaper	thispaper	NN
cord-104223-ht3ry9i0	13	5	:	:	:
cord-104223-ht3ry9i0	13	6	ASW	ASW	NNP
cord-104223-ht3ry9i0	13	7	,	,	,
cord-104223-ht3ry9i0	13	8	artificial	artificial	JJ
cord-104223-ht3ry9i0	13	9	sea	sea	NN
cord-104223-ht3ry9i0	13	10	water	water	NN
cord-104223-ht3ry9i0	13	11	;	;	:
cord-104223-ht3ry9i0	13	12	DCV	DCV	NNP
cord-104223-ht3ry9i0	13	13	,	,	,
cord-104223-ht3ry9i0	13	14	dense	dense	JJ
cord-104223-ht3ry9i0	13	15	core	core	NN
cord-104223-ht3ry9i0	13	16	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	13	17	;	;	:
cord-104223-ht3ry9i0	13	18	ELH	ELH	NNP
cord-104223-ht3ry9i0	13	19	,	,	,
cord-104223-ht3ry9i0	13	20	egg	egg	NN
cord-104223-ht3ry9i0	13	21	-	-	HYPH
cord-104223-ht3ry9i0	13	22	laying	lay	VBG
cord-104223-ht3ry9i0	13	23	hormone	hormone	NN
cord-104223-ht3ry9i0	13	24	;	;	:
cord-104223-ht3ry9i0	13	25	HD	hd	NN
cord-104223-ht3ry9i0	13	26	,	,	,
cord-104223-ht3ry9i0	13	27	half	half	JJ
cord-104223-ht3ry9i0	13	28	-	-	HYPH
cord-104223-ht3ry9i0	13	29	distance	distance	NN
cord-104223-ht3ry9i0	13	30	;	;	:
cord-104223-ht3ry9i0	13	31	Ile	Ile	NNP
cord-104223-ht3ry9i0	13	32	,	,	,
cord-104223-ht3ry9i0	13	33	isoleucine	isoleucine	NN
cord-104223-ht3ry9i0	13	34	;	;	:
cord-104223-ht3ry9i0	13	35	Phe	Phe	NNP
cord-104223-ht3ry9i0	13	36	,	,	,
cord-104223-ht3ry9i0	13	37	phenylalanine	phenylalanine	NN
cord-104223-ht3ry9i0	13	38	;	;	:
cord-104223-ht3ry9i0	13	39	TGN	TGN	NNP
cord-104223-ht3ry9i0	13	40	,	,	,
cord-104223-ht3ry9i0	13	41	trans	trans	NNP
cord-104223-ht3ry9i0	13	42	-	-	NNP
cord-104223-ht3ry9i0	13	43	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	13	44	network	network	NN
cord-104223-ht3ry9i0	13	45	.	.	.
cord-104223-ht3ry9i0	14	1	et	et	NNP
cord-104223-ht3ry9i0	14	2	al	al	NNP
cord-104223-ht3ry9i0	14	3	.	.	NNP
cord-104223-ht3ry9i0	14	4	,	,	,
cord-104223-ht3ry9i0	14	5	1988	1988	CD
cord-104223-ht3ry9i0	14	6	)	)	-RRB-
cord-104223-ht3ry9i0	14	7	.	.	.
cord-104223-ht3ry9i0	15	1	While	while	IN
cord-104223-ht3ry9i0	15	2	the	the	DT
cord-104223-ht3ry9i0	15	3	mechanism	mechanism	NN
cord-104223-ht3ry9i0	15	4	of	of	IN
cord-104223-ht3ry9i0	15	5	this	this	DT
cord-104223-ht3ry9i0	15	6	sorting	sorting	NN
cord-104223-ht3ry9i0	15	7	is	be	VBZ
cord-104223-ht3ry9i0	15	8	still	still	RB
cord-104223-ht3ry9i0	15	9	anknown	anknown	JJ
cord-104223-ht3ry9i0	15	10	,	,	,
cord-104223-ht3ry9i0	15	11	proposals	proposal	NNS
cord-104223-ht3ry9i0	15	12	have	have	VBP
cord-104223-ht3ry9i0	15	13	been	be	VBN
cord-104223-ht3ry9i0	15	14	made	make	VBN
cord-104223-ht3ry9i0	15	15	both	both	DT
cord-104223-ht3ry9i0	15	16	for	for	IN
cord-104223-ht3ry9i0	15	17	an	an	DT
cord-104223-ht3ry9i0	15	18	aggregation	aggregation	NN
cord-104223-ht3ry9i0	15	19	event	event	NN
cord-104223-ht3ry9i0	15	20	whereby	whereby	WRB
cord-104223-ht3ry9i0	15	21	the	the	DT
cord-104223-ht3ry9i0	15	22	condensation	condensation	NN
cord-104223-ht3ry9i0	15	23	of	of	IN
cord-104223-ht3ry9i0	15	24	neuropeptides	neuropeptide	NNS
cord-104223-ht3ry9i0	15	25	excludes	exclude	VBZ
cord-104223-ht3ry9i0	15	26	other	other	JJ
cord-104223-ht3ry9i0	15	27	proteins	protein	NNS
cord-104223-ht3ry9i0	15	28	from	from	IN
cord-104223-ht3ry9i0	15	29	the	the	DT
cord-104223-ht3ry9i0	15	30	forming	form	VBG
cord-104223-ht3ry9i0	15	31	DCV	DCV	NNP
cord-104223-ht3ry9i0	15	32	(	(	-LRB-
cord-104223-ht3ry9i0	15	33	Kelly	Kelly	NNP
cord-104223-ht3ry9i0	15	34	,	,	,
cord-104223-ht3ry9i0	15	35	1985	1985	CD
cord-104223-ht3ry9i0	15	36	)	)	-RRB-
cord-104223-ht3ry9i0	15	37	,	,	,
cord-104223-ht3ry9i0	15	38	and	and	CC
cord-104223-ht3ry9i0	15	39	a	a	DT
cord-104223-ht3ry9i0	15	40	receptor	receptor	NN
cord-104223-ht3ry9i0	15	41	-	-	HYPH
cord-104223-ht3ry9i0	15	42	mediated	mediate	VBN
cord-104223-ht3ry9i0	15	43	sorting	sorting	NN
cord-104223-ht3ry9i0	15	44	event	event	NN
cord-104223-ht3ry9i0	15	45	(	(	-LRB-
cord-104223-ht3ry9i0	15	46	Burgess	Burgess	NNP
cord-104223-ht3ry9i0	15	47	and	and	CC
cord-104223-ht3ry9i0	15	48	Kelly	Kelly	NNP
cord-104223-ht3ry9i0	15	49	,	,	,
cord-104223-ht3ry9i0	15	50	1987	1987	CD
cord-104223-ht3ry9i0	15	51	;	;	:
cord-104223-ht3ry9i0	15	52	Pfeffer	Pfeffer	NNP
cord-104223-ht3ry9i0	15	53	and	and	CC
cord-104223-ht3ry9i0	15	54	Rothman	Rothman	NNP
cord-104223-ht3ry9i0	15	55	,	,	,
cord-104223-ht3ry9i0	15	56	1987	1987	CD
cord-104223-ht3ry9i0	15	57	;	;	:
cord-104223-ht3ry9i0	15	58	Chung	Chung	NNP
cord-104223-ht3ry9i0	15	59	et	et	NNP
cord-104223-ht3ry9i0	15	60	al	al	NNP
cord-104223-ht3ry9i0	15	61	.	.	NNP
cord-104223-ht3ry9i0	15	62	,	,	,
cord-104223-ht3ry9i0	15	63	1989	1989	CD
cord-104223-ht3ry9i0	15	64	)	)	-RRB-
cord-104223-ht3ry9i0	15	65	analogous	analogous	JJ
cord-104223-ht3ry9i0	15	66	to	to	IN
cord-104223-ht3ry9i0	15	67	lysosomal	lysosomal	JJ
cord-104223-ht3ry9i0	15	68	sorting	sorting	NN
cord-104223-ht3ry9i0	15	69	where	where	WRB
cord-104223-ht3ry9i0	15	70	a	a	DT
cord-104223-ht3ry9i0	15	71	specific	specific	JJ
cord-104223-ht3ry9i0	15	72	signal	signal	NN
cord-104223-ht3ry9i0	15	73	(	(	-LRB-
cord-104223-ht3ry9i0	15	74	mannose-6phosphate	mannose-6phosphate	NN
cord-104223-ht3ry9i0	15	75	)	)	-RRB-
cord-104223-ht3ry9i0	15	76	targets	target	VBZ
cord-104223-ht3ry9i0	15	77	proteins	protein	NNS
cord-104223-ht3ry9i0	15	78	through	through	IN
cord-104223-ht3ry9i0	15	79	a	a	DT
cord-104223-ht3ry9i0	15	80	recycling	recycling	NN
cord-104223-ht3ry9i0	15	81	receptor	receptor	NN
cord-104223-ht3ry9i0	15	82	(	(	-LRB-
cord-104223-ht3ry9i0	15	83	Griffiths	Griffiths	NNP
cord-104223-ht3ry9i0	15	84	et	et	NNP
cord-104223-ht3ry9i0	15	85	al	al	NNP
cord-104223-ht3ry9i0	15	86	.	.	NNP
cord-104223-ht3ry9i0	15	87	,	,	,
cord-104223-ht3ry9i0	15	88	1988	1988	CD
cord-104223-ht3ry9i0	15	89	)	)	-RRB-
cord-104223-ht3ry9i0	15	90	.	.	.
cord-104223-ht3ry9i0	16	1	Sorting	sort	VBG
cord-104223-ht3ry9i0	16	2	within	within	IN
cord-104223-ht3ry9i0	16	3	the	the	DT
cord-104223-ht3ry9i0	16	4	regulated	regulate	VBN
cord-104223-ht3ry9i0	16	5	secretory	secretory	JJ
cord-104223-ht3ry9i0	16	6	pathway	pathway	NN
cord-104223-ht3ry9i0	16	7	has	have	VBZ
cord-104223-ht3ry9i0	16	8	recently	recently	RB
cord-104223-ht3ry9i0	16	9	been	be	VBN
cord-104223-ht3ry9i0	16	10	demonstrated	demonstrate	VBN
cord-104223-ht3ry9i0	16	11	both	both	CC
cord-104223-ht3ry9i0	16	12	in	in	IN
cord-104223-ht3ry9i0	16	13	Somatomammotrophs	Somatomammotrophs	NNP
cord-104223-ht3ry9i0	16	14	(	(	-LRB-
cord-104223-ht3ry9i0	16	15	Fumagalli	Fumagalli	NNP
cord-104223-ht3ry9i0	16	16	and	and	CC
cord-104223-ht3ry9i0	16	17	Zanini	Zanini	NNP
cord-104223-ht3ry9i0	16	18	,	,	,
cord-104223-ht3ry9i0	16	19	1985	1985	CD
cord-104223-ht3ry9i0	16	20	;	;	:
cord-104223-ht3ry9i0	16	21	Hashimoto	Hashimoto	NNP
cord-104223-ht3ry9i0	16	22	et	et	NNP
cord-104223-ht3ry9i0	16	23	al	al	NNP
cord-104223-ht3ry9i0	16	24	.	.	NNP
cord-104223-ht3ry9i0	16	25	,	,	,
cord-104223-ht3ry9i0	16	26	1987	1987	CD
cord-104223-ht3ry9i0	16	27	)	)	-RRB-
cord-104223-ht3ry9i0	16	28	and	and	CC
cord-104223-ht3ry9i0	16	29	in	in	IN
cord-104223-ht3ry9i0	16	30	the	the	DT
cord-104223-ht3ry9i0	16	31	bag	bag	NN
cord-104223-ht3ry9i0	16	32	cell	cell	NN
cord-104223-ht3ry9i0	16	33	neurons	neuron	NNS
cord-104223-ht3ry9i0	16	34	of	of	IN
cord-104223-ht3ry9i0	16	35	Aplysia	Aplysia	NNP
cord-104223-ht3ry9i0	16	36	californica	californica	NNP
cord-104223-ht3ry9i0	16	37	.	.	.
cord-104223-ht3ry9i0	17	1	In	in	IN
cord-104223-ht3ry9i0	17	2	the	the	DT
cord-104223-ht3ry9i0	17	3	bag	bag	NN
cord-104223-ht3ry9i0	17	4	cells	cell	NNS
cord-104223-ht3ry9i0	17	5	,	,	,
cord-104223-ht3ry9i0	17	6	different	different	JJ
cord-104223-ht3ry9i0	17	7	products	product	NNS
cord-104223-ht3ry9i0	17	8	of	of	IN
cord-104223-ht3ry9i0	17	9	the	the	DT
cord-104223-ht3ry9i0	17	10	egg	egg	NN
cord-104223-ht3ry9i0	17	11	-	-	HYPH
cord-104223-ht3ry9i0	17	12	laying	lay	VBG
cord-104223-ht3ry9i0	17	13	hormone	hormone	NN
cord-104223-ht3ry9i0	17	14	(	(	-LRB-
cord-104223-ht3ry9i0	17	15	ELH	ELH	NNP
cord-104223-ht3ry9i0	17	16	)	)	-RRB-
cord-104223-ht3ry9i0	17	17	precursor	precursor	NN
cord-104223-ht3ry9i0	17	18	are	be	VBP
cord-104223-ht3ry9i0	17	19	localized	localize	VBN
cord-104223-ht3ry9i0	17	20	to	to	IN
cord-104223-ht3ry9i0	17	21	separate	separate	JJ
cord-104223-ht3ry9i0	17	22	classes	class	NNS
cord-104223-ht3ry9i0	17	23	of	of	IN
cord-104223-ht3ry9i0	17	24	DCVs	dcv	NNS
cord-104223-ht3ry9i0	17	25	.	.	.
cord-104223-ht3ry9i0	18	1	Peptides	peptide	NNS
cord-104223-ht3ry9i0	18	2	from	from	IN
cord-104223-ht3ry9i0	18	3	the	the	DT
cord-104223-ht3ry9i0	18	4	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	18	5	-	-	HYPH
cord-104223-ht3ry9i0	18	6	terminal	terminal	NN
cord-104223-ht3ry9i0	18	7	side	side	NN
cord-104223-ht3ry9i0	18	8	of	of	IN
cord-104223-ht3ry9i0	18	9	the	the	DT
cord-104223-ht3ry9i0	18	10	ELH	ELH	NNP
cord-104223-ht3ry9i0	18	11	precursor	precursor	NN
cord-104223-ht3ry9i0	18	12	are	be	VBP
cord-104223-ht3ry9i0	18	13	found	find	VBN
cord-104223-ht3ry9i0	18	14	in	in	IN
cord-104223-ht3ry9i0	18	15	a	a	DT
cord-104223-ht3ry9i0	18	16	class	class	NN
cord-104223-ht3ry9i0	18	17	of	of	IN
cord-104223-ht3ry9i0	18	18	small	small	JJ
cord-104223-ht3ry9i0	18	19	DCVs	dcv	NNS
cord-104223-ht3ry9i0	18	20	which	which	WDT
cord-104223-ht3ry9i0	18	21	are	be	VBP
cord-104223-ht3ry9i0	18	22	rapidly	rapidly	RB
cord-104223-ht3ry9i0	18	23	transported	transport	VBN
cord-104223-ht3ry9i0	18	24	to	to	IN
cord-104223-ht3ry9i0	18	25	the	the	DT
cord-104223-ht3ry9i0	18	26	neuronal	neuronal	JJ
cord-104223-ht3ry9i0	18	27	processes	process	NNS
cord-104223-ht3ry9i0	18	28	,	,	,
cord-104223-ht3ry9i0	18	29	while	while	IN
cord-104223-ht3ry9i0	18	30	peptides	peptide	NNS
cord-104223-ht3ry9i0	18	31	from	from	IN
cord-104223-ht3ry9i0	18	32	the	the	DT
cord-104223-ht3ry9i0	18	33	amino	amino	NN
cord-104223-ht3ry9i0	18	34	-	-	HYPH
cord-104223-ht3ry9i0	18	35	terminal	terminal	NN
cord-104223-ht3ry9i0	18	36	side	side	NN
cord-104223-ht3ry9i0	18	37	of	of	IN
cord-104223-ht3ry9i0	18	38	the	the	DT
cord-104223-ht3ry9i0	18	39	precursor	precursor	NN
cord-104223-ht3ry9i0	18	40	are	be	VBP
cord-104223-ht3ry9i0	18	41	found	find	VBN
cord-104223-ht3ry9i0	18	42	both	both	CC
cord-104223-ht3ry9i0	18	43	in	in	IN
cord-104223-ht3ry9i0	18	44	a	a	DT
cord-104223-ht3ry9i0	18	45	class	class	NN
cord-104223-ht3ry9i0	18	46	of	of	IN
cord-104223-ht3ry9i0	18	47	large	large	JJ
cord-104223-ht3ry9i0	18	48	DCVs	dcv	NNS
cord-104223-ht3ry9i0	18	49	that	that	WDT
cord-104223-ht3ry9i0	18	50	are	be	VBP
cord-104223-ht3ry9i0	18	51	restricted	restrict	VBN
cord-104223-ht3ry9i0	18	52	to	to	IN
cord-104223-ht3ry9i0	18	53	the	the	DT
cord-104223-ht3ry9i0	18	54	cell	cell	NN
cord-104223-ht3ry9i0	18	55	body	body	NN
cord-104223-ht3ry9i0	18	56	and	and	CC
cord-104223-ht3ry9i0	18	57	a	a	DT
cord-104223-ht3ry9i0	18	58	distinct	distinct	JJ
cord-104223-ht3ry9i0	18	59	class	class	NN
cord-104223-ht3ry9i0	18	60	of	of	IN
cord-104223-ht3ry9i0	18	61	small	small	JJ
cord-104223-ht3ry9i0	18	62	DCVs	dcv	NNS
cord-104223-ht3ry9i0	18	63	which	which	WDT
cord-104223-ht3ry9i0	18	64	are	be	VBP
cord-104223-ht3ry9i0	18	65	transported	transport	VBN
cord-104223-ht3ry9i0	18	66	to	to	IN
cord-104223-ht3ry9i0	18	67	processes	process	NNS
cord-104223-ht3ry9i0	18	68	(	(	-LRB-
cord-104223-ht3ry9i0	18	69	Fig	fig	NN
cord-104223-ht3ry9i0	18	70	.	.	.
cord-104223-ht3ry9i0	18	71	1	1	CD
cord-104223-ht3ry9i0	18	72	)	)	-RRB-
cord-104223-ht3ry9i0	18	73	.	.	.
cord-104223-ht3ry9i0	19	1	This	this	DT
cord-104223-ht3ry9i0	19	2	sorting	sorting	NN
cord-104223-ht3ry9i0	19	3	event	event	NN
cord-104223-ht3ry9i0	19	4	has	have	VBZ
cord-104223-ht3ry9i0	19	5	important	important	JJ
cord-104223-ht3ry9i0	19	6	physiological	physiological	JJ
cord-104223-ht3ry9i0	19	7	consequences	consequence	NNS
cord-104223-ht3ry9i0	19	8	as	as	IN
cord-104223-ht3ry9i0	19	9	the	the	DT
cord-104223-ht3ry9i0	19	10	different	different	JJ
cord-104223-ht3ry9i0	19	11	regions	region	NNS
cord-104223-ht3ry9i0	19	12	of	of	IN
cord-104223-ht3ry9i0	19	13	the	the	DT
cord-104223-ht3ry9i0	19	14	ELH	ELH	NNP
cord-104223-ht3ry9i0	19	15	prohormone	prohormone	NN
cord-104223-ht3ry9i0	19	16	contain	contain	VBP
cord-104223-ht3ry9i0	19	17	peptides	peptide	NNS
cord-104223-ht3ry9i0	19	18	with	with	IN
cord-104223-ht3ry9i0	19	19	unique	unique	JJ
cord-104223-ht3ry9i0	19	20	biological	biological	JJ
cord-104223-ht3ry9i0	19	21	activities	activity	NNS
cord-104223-ht3ry9i0	19	22	(	(	-LRB-
cord-104223-ht3ry9i0	19	23	Kupfermann	Kupfermann	NNP
cord-104223-ht3ry9i0	19	24	,	,	,
cord-104223-ht3ry9i0	19	25	1967	1967	CD
cord-104223-ht3ry9i0	19	26	;	;	.
cord-104223-ht3ry9i0	20	1	Rothman	Rothman	NNP
cord-104223-ht3ry9i0	20	2	et	et	NNP
cord-104223-ht3ry9i0	20	3	al	al	NNP
cord-104223-ht3ry9i0	20	4	.	.	NNP
cord-104223-ht3ry9i0	20	5	,	,	,
cord-104223-ht3ry9i0	20	6	1983a	1983a	CD
cord-104223-ht3ry9i0	20	7	,	,	,
cord-104223-ht3ry9i0	20	8	b	b	LS
cord-104223-ht3ry9i0	20	9	;	;	:
cord-104223-ht3ry9i0	20	10	Mayeri	Mayeri	NNP
cord-104223-ht3ry9i0	20	11	et	et	NNP
cord-104223-ht3ry9i0	20	12	al	al	NNP
cord-104223-ht3ry9i0	20	13	.	.	NNP
cord-104223-ht3ry9i0	20	14	,	,	,
cord-104223-ht3ry9i0	20	15	1985	1985	CD
cord-104223-ht3ry9i0	21	1	;	;	:
cord-104223-ht3ry9i0	21	2	Kauer	Kauer	NNP
cord-104223-ht3ry9i0	21	3	et	et	NNP
cord-104223-ht3ry9i0	21	4	al	al	NNP
cord-104223-ht3ry9i0	21	5	.	.	NNP
cord-104223-ht3ry9i0	21	6	,	,	,
cord-104223-ht3ry9i0	21	7	1987	1987	CD
cord-104223-ht3ry9i0	21	8	;	;	.
cord-104223-ht3ry9i0	22	1	Brown	Brown	NNP
cord-104223-ht3ry9i0	22	2	and	and	CC
cord-104223-ht3ry9i0	22	3	Mayeri	Mayeri	NNP
cord-104223-ht3ry9i0	22	4	,	,	,
cord-104223-ht3ry9i0	22	5	1989	1989	CD
cord-104223-ht3ry9i0	22	6	)	)	-RRB-
cord-104223-ht3ry9i0	22	7	.	.	.
cord-104223-ht3ry9i0	23	1	In	in	IN
cord-104223-ht3ry9i0	23	2	this	this	DT
cord-104223-ht3ry9i0	23	3	paper	paper	NN
cord-104223-ht3ry9i0	23	4	,	,	,
cord-104223-ht3ry9i0	23	5	we	-PRON-	PRP
cord-104223-ht3ry9i0	23	6	investigate	investigate	VBP
cord-104223-ht3ry9i0	23	7	the	the	DT
cord-104223-ht3ry9i0	23	8	cellular	cellular	JJ
cord-104223-ht3ry9i0	23	9	pathway	pathway	NN
cord-104223-ht3ry9i0	23	10	of	of	IN
cord-104223-ht3ry9i0	23	11	protein	protein	NN
cord-104223-ht3ry9i0	23	12	trafficking	trafficking	NN
cord-104223-ht3ry9i0	23	13	within	within	IN
cord-104223-ht3ry9i0	23	14	the	the	DT
cord-104223-ht3ry9i0	23	15	bag	bag	NN
cord-104223-ht3ry9i0	23	16	cells	cell	NNS
cord-104223-ht3ry9i0	23	17	using	use	VBG
cord-104223-ht3ry9i0	23	18	EM	EM	NNP
cord-104223-ht3ry9i0	23	19	autoradiography	autoradiography	NNP
cord-104223-ht3ry9i0	23	20	and	and	CC
cord-104223-ht3ry9i0	23	21	the	the	DT
cord-104223-ht3ry9i0	23	22	carboxylic	carboxylic	JJ
cord-104223-ht3ry9i0	23	23	acid	acid	NN
cord-104223-ht3ry9i0	23	24	ionophore	ionophore	NNP
cord-104223-ht3ry9i0	23	25	monensin	monensin	NNP
cord-104223-ht3ry9i0	23	26	.	.	.
cord-104223-ht3ry9i0	24	1	The	the	DT
cord-104223-ht3ry9i0	24	2	bag	bag	NN
cord-104223-ht3ry9i0	24	3	cells	cell	NNS
cord-104223-ht3ry9i0	24	4	have	have	VBP
cord-104223-ht3ry9i0	24	5	two	two	CD
cord-104223-ht3ry9i0	24	6	features	feature	NNS
cord-104223-ht3ry9i0	24	7	that	that	WDT
cord-104223-ht3ry9i0	24	8	facilitate	facilitate	VBP
cord-104223-ht3ry9i0	24	9	these	these	DT
cord-104223-ht3ry9i0	24	10	studies	study	NNS
cord-104223-ht3ry9i0	24	11	;	;	,
cord-104223-ht3ry9i0	24	12	(	(	-LRB-
cord-104223-ht3ry9i0	24	13	a	a	LS
cord-104223-ht3ry9i0	24	14	)	)	-RRB-
cord-104223-ht3ry9i0	24	15	the	the	DT
cord-104223-ht3ry9i0	24	16	ELH	ELH	NNP
cord-104223-ht3ry9i0	24	17	prohormone	prohormone	NN
cord-104223-ht3ry9i0	24	18	is	be	VBZ
cord-104223-ht3ry9i0	24	19	the	the	DT
cord-104223-ht3ry9i0	24	20	major	major	JJ
cord-104223-ht3ry9i0	24	21	protein	protein	NN
cord-104223-ht3ry9i0	24	22	produced	produce	VBN
cord-104223-ht3ry9i0	24	23	by	by	IN
cord-104223-ht3ry9i0	24	24	the	the	DT
cord-104223-ht3ry9i0	24	25	bag	bag	NN
cord-104223-ht3ry9i0	24	26	cells	cell	NNS
cord-104223-ht3ry9i0	24	27	and	and	CC
cord-104223-ht3ry9i0	24	28	accounts	account	VBZ
cord-104223-ht3ry9i0	24	29	for	for	IN
cord-104223-ht3ry9i0	24	30	up	up	IN
cord-104223-ht3ry9i0	24	31	to	to	TO
cord-104223-ht3ry9i0	24	32	50	50	CD
cord-104223-ht3ry9i0	24	33	%	%	NN
cord-104223-ht3ry9i0	24	34	of	of	IN
cord-104223-ht3ry9i0	24	35	the	the	DT
cord-104223-ht3ry9i0	24	36	translated	translate	VBN
cord-104223-ht3ry9i0	24	37	protein	protein	NN
cord-104223-ht3ry9i0	24	38	(	(	-LRB-
cord-104223-ht3ry9i0	24	39	Berry	Berry	NNP
cord-104223-ht3ry9i0	24	40	and	and	CC
cord-104223-ht3ry9i0	24	41	Arch	Arch	NNP
cord-104223-ht3ry9i0	24	42	,	,	,
cord-104223-ht3ry9i0	24	43	1981	1981	CD
cord-104223-ht3ry9i0	24	44	;	;	:
cord-104223-ht3ry9i0	24	45	Scheller	Scheller	NNP
cord-104223-ht3ry9i0	24	46	et	et	NNP
cord-104223-ht3ry9i0	24	47	al	al	NNP
cord-104223-ht3ry9i0	24	48	.	.	NNP
cord-104223-ht3ry9i0	24	49	,	,	,
cord-104223-ht3ry9i0	24	50	1983	1983	CD
cord-104223-ht3ry9i0	24	51	)	)	-RRB-
cord-104223-ht3ry9i0	24	52	;	;	:
cord-104223-ht3ry9i0	24	53	(	(	-LRB-
cord-104223-ht3ry9i0	24	54	b	b	NN
cord-104223-ht3ry9i0	24	55	)	)	-RRB-
cord-104223-ht3ry9i0	24	56	an	an	DT
cord-104223-ht3ry9i0	24	57	asymmetric	asymmetric	JJ
cord-104223-ht3ry9i0	24	58	distribution	distribution	NN
cord-104223-ht3ry9i0	24	59	of	of	IN
cord-104223-ht3ry9i0	24	60	amino	amino	JJ
cord-104223-ht3ry9i0	24	61	acids	acid	NNS
cord-104223-ht3ry9i0	24	62	across	across	IN
cord-104223-ht3ry9i0	24	63	the	the	DT
cord-104223-ht3ry9i0	24	64	prohormone	prohormone	NN
cord-104223-ht3ry9i0	24	65	Fig	Fig	NNP
cord-104223-ht3ry9i0	24	66	.	.	NNP
cord-104223-ht3ry9i0	24	67	1	1	CD
cord-104223-ht3ry9i0	24	68	)	)	-RRB-
cord-104223-ht3ry9i0	24	69	allows	allow	VBZ
cord-104223-ht3ry9i0	24	70	the	the	DT
cord-104223-ht3ry9i0	24	71	selective	selective	JJ
cord-104223-ht3ry9i0	24	72	labeling	labeling	NN
cord-104223-ht3ry9i0	24	73	of	of	IN
cord-104223-ht3ry9i0	24	74	the	the	DT
cord-104223-ht3ry9i0	24	75	sorted	sort	VBN
cord-104223-ht3ry9i0	24	76	carboxy	carboxy	NN
cord-104223-ht3ry9i0	24	77	or	or	CC
cord-104223-ht3ry9i0	24	78	amino	amino	NN
cord-104223-ht3ry9i0	24	79	terminal	terminal	NN
cord-104223-ht3ry9i0	24	80	-	-	HYPH
cord-104223-ht3ry9i0	24	81	derived	derive	VBN
cord-104223-ht3ry9i0	24	82	peptides	peptide	NNS
cord-104223-ht3ry9i0	24	83	.	.	.
cord-104223-ht3ry9i0	25	1	In	in	IN
cord-104223-ht3ry9i0	25	2	this	this	DT
cord-104223-ht3ry9i0	25	3	study	study	NN
cord-104223-ht3ry9i0	25	4	,	,	,
cord-104223-ht3ry9i0	25	5	we	-PRON-	PRP
cord-104223-ht3ry9i0	25	6	use	use	VBP
cord-104223-ht3ry9i0	25	7	these	these	DT
cord-104223-ht3ry9i0	25	8	properties	property	NNS
cord-104223-ht3ry9i0	25	9	to	to	TO
cord-104223-ht3ry9i0	25	10	selectively	selectively	RB
cord-104223-ht3ry9i0	25	11	follow	follow	VB
cord-104223-ht3ry9i0	25	12	the	the	DT
cord-104223-ht3ry9i0	25	13	flow	flow	NN
cord-104223-ht3ry9i0	25	14	of	of	IN
cord-104223-ht3ry9i0	25	15	neuropeptides	neuropeptide	NNS
cord-104223-ht3ry9i0	25	16	derived	derive	VBN
cord-104223-ht3ry9i0	25	17	from	from	IN
cord-104223-ht3ry9i0	25	18	the	the	DT
cord-104223-ht3ry9i0	25	19	ELH	ELH	NNP
cord-104223-ht3ry9i0	25	20	precursor	precursor	NN
cord-104223-ht3ry9i0	25	21	through	through	IN
cord-104223-ht3ry9i0	25	22	the	the	DT
cord-104223-ht3ry9i0	25	23	secretory	secretory	JJ
cord-104223-ht3ry9i0	25	24	pathway	pathway	NN
cord-104223-ht3ry9i0	25	25	.	.	.
cord-104223-ht3ry9i0	26	1	The	the	DT
cord-104223-ht3ry9i0	26	2	results	result	NNS
cord-104223-ht3ry9i0	26	3	suggest	suggest	VBP
cord-104223-ht3ry9i0	26	4	possible	possible	JJ
cord-104223-ht3ry9i0	26	5	mechanisms	mechanism	NNS
cord-104223-ht3ry9i0	26	6	that	that	WDT
cord-104223-ht3ry9i0	26	7	underlie	underlie	VBP
cord-104223-ht3ry9i0	26	8	sorting	sort	VBG
cord-104223-ht3ry9i0	26	9	within	within	IN
cord-104223-ht3ry9i0	26	10	the	the	DT
cord-104223-ht3ry9i0	26	11	regulated	regulate	VBN
cord-104223-ht3ry9i0	26	12	secretory	secretory	JJ
cord-104223-ht3ry9i0	26	13	pathway	pathway	NN
cord-104223-ht3ry9i0	26	14	.	.	.
cord-104223-ht3ry9i0	27	1	250	250	CD
cord-104223-ht3ry9i0	27	2	-	-	HYPH
cord-104223-ht3ry9i0	27	3	750-g	750-g	CD
cord-104223-ht3ry9i0	28	1	Aplysia	Aplysia	NNP
cord-104223-ht3ry9i0	28	2	were	be	VBD
cord-104223-ht3ry9i0	28	3	obtained	obtain	VBN
cord-104223-ht3ry9i0	28	4	from	from	IN
cord-104223-ht3ry9i0	28	5	Sea	Sea	NNP
cord-104223-ht3ry9i0	28	6	Life	Life	NNP
cord-104223-ht3ry9i0	28	7	Supply	Supply	NNP
cord-104223-ht3ry9i0	28	8	(	(	-LRB-
cord-104223-ht3ry9i0	28	9	Sand	Sand	NNP
cord-104223-ht3ry9i0	28	10	City	City	NNP
cord-104223-ht3ry9i0	28	11	,	,	,
cord-104223-ht3ry9i0	28	12	CA	CA	NNP
cord-104223-ht3ry9i0	28	13	)	)	-RRB-
cord-104223-ht3ry9i0	28	14	.	.	.
cord-104223-ht3ry9i0	29	1	Bag	bag	NN
cord-104223-ht3ry9i0	29	2	ceil	ceil	NN
cord-104223-ht3ry9i0	29	3	clusters	cluster	NNS
cord-104223-ht3ry9i0	29	4	were	be	VBD
cord-104223-ht3ry9i0	29	5	isolated	isolate	VBN
cord-104223-ht3ry9i0	29	6	and	and	CC
cord-104223-ht3ry9i0	29	7	equilibrated	equilibrate	VBN
cord-104223-ht3ry9i0	29	8	in	in	IN
cord-104223-ht3ry9i0	29	9	artificial	artificial	JJ
cord-104223-ht3ry9i0	29	10	sea	sea	NN
cord-104223-ht3ry9i0	29	11	water	water	NN
cord-104223-ht3ry9i0	29	12	(	(	-LRB-
cord-104223-ht3ry9i0	29	13	ASW	ASW	NNP
cord-104223-ht3ry9i0	29	14	;	;	:
cord-104223-ht3ry9i0	29	15	490	490	CD
cord-104223-ht3ry9i0	29	16	mM	mm	CD
cord-104223-ht3ry9i0	29	17	NaCI	naci	NN
cord-104223-ht3ry9i0	29	18	,	,	,
cord-104223-ht3ry9i0	29	19	11	11	CD
cord-104223-ht3ry9i0	29	20	mM	mm	CD
cord-104223-ht3ry9i0	29	21	KCI	KCI	NNP
cord-104223-ht3ry9i0	29	22	,	,	,
cord-104223-ht3ry9i0	29	23	19	19	CD
cord-104223-ht3ry9i0	29	24	mM	mm	CD
cord-104223-ht3ry9i0	29	25	MgCI2	MgCI2	NNP
cord-104223-ht3ry9i0	29	26	,	,	,
cord-104223-ht3ry9i0	29	27	30	30	CD
cord-104223-ht3ry9i0	29	28	mM	mm	CD
cord-104223-ht3ry9i0	29	29	MgSO4	MgSO4	NNP
cord-104223-ht3ry9i0	29	30	,	,	,
cord-104223-ht3ry9i0	29	31	11	11	CD
cord-104223-ht3ry9i0	29	32	mM	mM	NNP
cord-104223-ht3ry9i0	29	33	CaCI2	CaCI2	NNP
cord-104223-ht3ry9i0	29	34	,	,	,
cord-104223-ht3ry9i0	29	35	and	and	CC
cord-104223-ht3ry9i0	29	36	10	10	CD
cord-104223-ht3ry9i0	29	37	mM	mm	CD
cord-104223-ht3ry9i0	29	38	Tris	Tris	NNP
cord-104223-ht3ry9i0	29	39	,	,	,
cord-104223-ht3ry9i0	29	40	pH	pH	NNP
cord-104223-ht3ry9i0	29	41	7.6	7.6	CD
cord-104223-ht3ry9i0	29	42	)	)	-RRB-
cord-104223-ht3ry9i0	29	43	at	at	IN
cord-104223-ht3ry9i0	29	44	14	14	CD
cord-104223-ht3ry9i0	29	45	°	°	NN
cord-104223-ht3ry9i0	29	46	C	c	NN
cord-104223-ht3ry9i0	29	47	for	for	IN
cord-104223-ht3ry9i0	29	48	30	30	CD
cord-104223-ht3ry9i0	29	49	rain	rain	NN
cord-104223-ht3ry9i0	29	50	.	.	.
cord-104223-ht3ry9i0	30	1	The	the	DT
cord-104223-ht3ry9i0	30	2	clusters	cluster	NNS
cord-104223-ht3ry9i0	30	3	were	be	VBD
cord-104223-ht3ry9i0	30	4	then	then	RB
cord-104223-ht3ry9i0	30	5	incubated	incubate	VBN
cord-104223-ht3ry9i0	30	6	in	in	IN
cord-104223-ht3ry9i0	30	7	isoleucine	isoleucine	NNP
cord-104223-ht3ry9i0	30	8	(	(	-LRB-
cord-104223-ht3ry9i0	30	9	[	[	-LRB-
cord-104223-ht3ry9i0	30	10	3H	3H	NNP
cord-104223-ht3ry9i0	30	11	]	]	-RRB-
cord-104223-ht3ry9i0	30	12	Ile	Ile	NNP
cord-104223-ht3ry9i0	30	13	)	)	-RRB-
cord-104223-ht3ry9i0	30	14	or	or	CC
cord-104223-ht3ry9i0	30	15	L-[2	L-[2	NNP
cord-104223-ht3ry9i0	30	16	,	,	,
cord-104223-ht3ry9i0	30	17	3	3	CD
cord-104223-ht3ry9i0	30	18	,	,	,
cord-104223-ht3ry9i0	30	19	4	4	CD
cord-104223-ht3ry9i0	30	20	,	,	,
cord-104223-ht3ry9i0	30	21	5	5	CD
cord-104223-ht3ry9i0	30	22	,	,	,
cord-104223-ht3ry9i0	30	23	6	6	CD
cord-104223-ht3ry9i0	30	24	-	-	SYM
cord-104223-ht3ry9i0	30	25	3H]phenylalanine	3h]phenylalanine	CD
cord-104223-ht3ry9i0	31	1	(	(	-LRB-
cord-104223-ht3ry9i0	31	2	[	[	-LRB-
cord-104223-ht3ry9i0	31	3	3H]-Phe)(Amersham	3h]-phe)(amersham	CD
cord-104223-ht3ry9i0	31	4	Corp.	Corp.	NNP
cord-104223-ht3ry9i0	31	5	,	,	,
cord-104223-ht3ry9i0	31	6	Arlington	Arlington	NNP
cord-104223-ht3ry9i0	31	7	Heights	Heights	NNP
cord-104223-ht3ry9i0	31	8	,	,	,
cord-104223-ht3ry9i0	31	9	IL	IL	NNP
cord-104223-ht3ry9i0	31	10	)	)	-RRB-
cord-104223-ht3ry9i0	31	11	(	(	-LRB-
cord-104223-ht3ry9i0	31	12	1	1	CD
cord-104223-ht3ry9i0	31	13	mCi	mCi	NNPS
cord-104223-ht3ry9i0	31	14	/	/	SYM
cord-104223-ht3ry9i0	31	15	ml	ml	XX
cord-104223-ht3ry9i0	31	16	for	for	IN
cord-104223-ht3ry9i0	31	17	a	a	DT
cord-104223-ht3ry9i0	31	18	30-rain	30-rain	CD
cord-104223-ht3ry9i0	31	19	pulse	pulse	NN
cord-104223-ht3ry9i0	31	20	;	;	:
cord-104223-ht3ry9i0	31	21	4	4	CD
cord-104223-ht3ry9i0	31	22	mCi	mCi	NNPS
cord-104223-ht3ry9i0	31	23	/	/	SYM
cord-104223-ht3ry9i0	31	24	mi	mi	NNP
cord-104223-ht3ry9i0	31	25	for	for	IN
cord-104223-ht3ry9i0	31	26	a	a	DT
cord-104223-ht3ry9i0	31	27	5-rain	5-rain	CD
cord-104223-ht3ry9i0	31	28	pulse	pulse	NN
cord-104223-ht3ry9i0	31	29	)	)	-RRB-
cord-104223-ht3ry9i0	31	30	for	for	IN
cord-104223-ht3ry9i0	31	31	either	either	DT
cord-104223-ht3ry9i0	31	32	5	5	CD
cord-104223-ht3ry9i0	31	33	or	or	CC
cord-104223-ht3ry9i0	31	34	30	30	CD
cord-104223-ht3ry9i0	31	35	min	min	NN
cord-104223-ht3ry9i0	31	36	and	and	CC
cord-104223-ht3ry9i0	31	37	then	then	RB
cord-104223-ht3ry9i0	31	38	chased	chase	VBD
cord-104223-ht3ry9i0	31	39	with	with	IN
cord-104223-ht3ry9i0	31	40	ASW	ASW	NNP
cord-104223-ht3ry9i0	31	41	plus	plus	CC
cord-104223-ht3ry9i0	31	42	1	1	CD
cord-104223-ht3ry9i0	31	43	mM	mm	CD
cord-104223-ht3ry9i0	31	44	Phe	Phe	NNP
cord-104223-ht3ry9i0	31	45	,	,	,
cord-104223-ht3ry9i0	31	46	ASW	ASW	NNP
cord-104223-ht3ry9i0	31	47	plus	plus	CC
cord-104223-ht3ry9i0	31	48	1	1	CD
cord-104223-ht3ry9i0	31	49	mM	mM	NNP
cord-104223-ht3ry9i0	31	50	Ile	Ile	NNP
cord-104223-ht3ry9i0	31	51	,	,	,
cord-104223-ht3ry9i0	31	52	or	or	CC
cord-104223-ht3ry9i0	31	53	isotonic	isotonic	JJ
cord-104223-ht3ry9i0	31	54	LI5	LI5	NNP
cord-104223-ht3ry9i0	31	55	plus	plus	CC
cord-104223-ht3ry9i0	31	56	1	1	CD
cord-104223-ht3ry9i0	31	57	mM	mm	CD
cord-104223-ht3ry9i0	31	58	Phe	Phe	NNP
cord-104223-ht3ry9i0	31	59	for	for	IN
cord-104223-ht3ry9i0	31	60	the	the	DT
cord-104223-ht3ry9i0	31	61	12-h	12-h	CD
cord-104223-ht3ry9i0	31	62	chase	chase	NN
cord-104223-ht3ry9i0	31	63	at	at	IN
cord-104223-ht3ry9i0	31	64	14	14	CD
cord-104223-ht3ry9i0	31	65	°	°	NN
cord-104223-ht3ry9i0	31	66	C	c	NN
cord-104223-ht3ry9i0	31	67	.	.	.
cord-104223-ht3ry9i0	32	1	The	the	DT
cord-104223-ht3ry9i0	32	2	chase	chase	NN
cord-104223-ht3ry9i0	32	3	was	be	VBD
cord-104223-ht3ry9i0	32	4	stopped	stop	VBN
cord-104223-ht3ry9i0	32	5	by	by	IN
cord-104223-ht3ry9i0	32	6	placing	place	VBG
cord-104223-ht3ry9i0	32	7	the	the	DT
cord-104223-ht3ry9i0	32	8	clusters	cluster	NNS
cord-104223-ht3ry9i0	32	9	into	into	IN
cord-104223-ht3ry9i0	32	10	a	a	DT
cord-104223-ht3ry9i0	32	11	fixation	fixation	NN
cord-104223-ht3ry9i0	32	12	solution	solution	NN
cord-104223-ht3ry9i0	32	13	consisting	consist	VBG
cord-104223-ht3ry9i0	32	14	of	of	IN
cord-104223-ht3ry9i0	32	15	2	2	CD
cord-104223-ht3ry9i0	32	16	%	%	NN
cord-104223-ht3ry9i0	32	17	glutaraldehyde	glutaraldehyde	NN
cord-104223-ht3ry9i0	32	18	,	,	,
cord-104223-ht3ry9i0	32	19	2	2	CD
cord-104223-ht3ry9i0	32	20	%	%	NN
cord-104223-ht3ry9i0	32	21	paraformaldehyde	paraformaldehyde	NNP
cord-104223-ht3ry9i0	32	22	,	,	,
cord-104223-ht3ry9i0	32	23	1	1	CD
cord-104223-ht3ry9i0	32	24	%	%	NN
cord-104223-ht3ry9i0	32	25	DMSO	DMSO	NNP
cord-104223-ht3ry9i0	32	26	,	,	,
cord-104223-ht3ry9i0	32	27	0.3	0.3	CD
cord-104223-ht3ry9i0	32	28	M	m	NN
cord-104223-ht3ry9i0	32	29	sucrose	sucrose	NN
cord-104223-ht3ry9i0	32	30	in	in	IN
cord-104223-ht3ry9i0	32	31	PBS	PBS	NNP
cord-104223-ht3ry9i0	32	32	(	(	-LRB-
cord-104223-ht3ry9i0	32	33	0.137	0.137	CD
cord-104223-ht3ry9i0	32	34	M	M	NNP
cord-104223-ht3ry9i0	32	35	NaC1	NaC1	NNP
cord-104223-ht3ry9i0	32	36	,	,	,
cord-104223-ht3ry9i0	32	37	25.5	25.5	CD
cord-104223-ht3ry9i0	32	38	mM	mm	CD
cord-104223-ht3ry9i0	32	39	KCI	KCI	NNP
cord-104223-ht3ry9i0	32	40	,	,	,
cord-104223-ht3ry9i0	32	41	8	8	CD
cord-104223-ht3ry9i0	32	42	mM	mm	CD
cord-104223-ht3ry9i0	32	43	Na2PO4	na2po4	NN
cord-104223-ht3ry9i0	32	44	,	,	,
cord-104223-ht3ry9i0	32	45	1.5	1.5	CD
cord-104223-ht3ry9i0	32	46	mM	mm	CD
cord-104223-ht3ry9i0	32	47	KH2PO4	kh2po4	NN
cord-104223-ht3ry9i0	32	48	,	,	,
cord-104223-ht3ry9i0	32	49	pH	pH	NNP
cord-104223-ht3ry9i0	32	50	7.4	7.4	CD
cord-104223-ht3ry9i0	32	51	)	)	-RRB-
cord-104223-ht3ry9i0	32	52	.	.	.
cord-104223-ht3ry9i0	33	1	Occasionally	occasionally	RB
cord-104223-ht3ry9i0	33	2	,	,	,
cord-104223-ht3ry9i0	33	3	1	1	CD
cord-104223-ht3ry9i0	33	4	%	%	NN
cord-104223-ht3ry9i0	33	5	acrolein	acrolein	NN
cord-104223-ht3ry9i0	33	6	was	be	VBD
cord-104223-ht3ry9i0	33	7	also	also	RB
cord-104223-ht3ry9i0	33	8	included	include	VBN
cord-104223-ht3ry9i0	33	9	in	in	IN
cord-104223-ht3ry9i0	33	10	the	the	DT
cord-104223-ht3ry9i0	33	11	fixation	fixation	NN
cord-104223-ht3ry9i0	33	12	solution	solution	NN
cord-104223-ht3ry9i0	33	13	.	.	.
cord-104223-ht3ry9i0	34	1	The	the	DT
cord-104223-ht3ry9i0	34	2	tissue	tissue	NN
cord-104223-ht3ry9i0	34	3	was	be	VBD
cord-104223-ht3ry9i0	34	4	fixed	fix	VBN
cord-104223-ht3ry9i0	34	5	for	for	IN
cord-104223-ht3ry9i0	34	6	4	4	CD
cord-104223-ht3ry9i0	34	7	-	-	SYM
cord-104223-ht3ry9i0	34	8	6	6	CD
cord-104223-ht3ry9i0	34	9	h	h	NN
cord-104223-ht3ry9i0	34	10	at	at	IN
cord-104223-ht3ry9i0	34	11	room	room	NN
cord-104223-ht3ry9i0	34	12	temperature	temperature	NN
cord-104223-ht3ry9i0	34	13	(	(	-LRB-
cord-104223-ht3ry9i0	34	14	occasionally	occasionally	RB
cord-104223-ht3ry9i0	34	15	overnight	overnight	RB
cord-104223-ht3ry9i0	34	16	at	at	IN
cord-104223-ht3ry9i0	34	17	4	4	CD
cord-104223-ht3ry9i0	34	18	°	°	NN
cord-104223-ht3ry9i0	34	19	C	C	NNP
cord-104223-ht3ry9i0	34	20	)	)	-RRB-
cord-104223-ht3ry9i0	34	21	.	.	.
cord-104223-ht3ry9i0	35	1	The	the	DT
cord-104223-ht3ry9i0	35	2	clusters	cluster	NNS
cord-104223-ht3ry9i0	35	3	were	be	VBD
cord-104223-ht3ry9i0	35	4	rinsed	rinse	VBN
cord-104223-ht3ry9i0	35	5	with	with	IN
cord-104223-ht3ry9i0	35	6	PBS	PBS	NNP
cord-104223-ht3ry9i0	35	7	,	,	,
cord-104223-ht3ry9i0	35	8	desheathed	desheathed	NNP
cord-104223-ht3ry9i0	35	9	,	,	,
cord-104223-ht3ry9i0	35	10	and	and	CC
cord-104223-ht3ry9i0	35	11	osmicated	osmicate	VBD
cord-104223-ht3ry9i0	35	12	with	with	IN
cord-104223-ht3ry9i0	35	13	2	2	CD
cord-104223-ht3ry9i0	35	14	%	%	NN
cord-104223-ht3ry9i0	35	15	OsO4	oso4	IN
cord-104223-ht3ry9i0	35	16	in	in	IN
cord-104223-ht3ry9i0	35	17	PBS	PBS	NNP
cord-104223-ht3ry9i0	35	18	for	for	IN
cord-104223-ht3ry9i0	35	19	2	2	CD
cord-104223-ht3ry9i0	35	20	h	h	NN
cord-104223-ht3ry9i0	35	21	followed	follow	VBN
cord-104223-ht3ry9i0	35	22	by	by	IN
cord-104223-ht3ry9i0	35	23	four	four	CD
cord-104223-ht3ry9i0	35	24	washes	wash	NNS
cord-104223-ht3ry9i0	35	25	in	in	IN
cord-104223-ht3ry9i0	35	26	DDH20	DDH20	NNP
cord-104223-ht3ry9i0	35	27	and	and	CC
cord-104223-ht3ry9i0	35	28	an	an	DT
cord-104223-ht3ry9i0	35	29	additional	additional	JJ
cord-104223-ht3ry9i0	35	30	2	2	CD
cord-104223-ht3ry9i0	35	31	h	h	NN
cord-104223-ht3ry9i0	35	32	in	in	IN
cord-104223-ht3ry9i0	35	33	2	2	CD
cord-104223-ht3ry9i0	35	34	%	%	NN
cord-104223-ht3ry9i0	35	35	aqueous	aqueous	JJ
cord-104223-ht3ry9i0	35	36	uranyl	uranyl	NN
cord-104223-ht3ry9i0	35	37	acetate	acetate	NN
cord-104223-ht3ry9i0	35	38	.	.	.
cord-104223-ht3ry9i0	36	1	The	the	DT
cord-104223-ht3ry9i0	36	2	clusters	cluster	NNS
cord-104223-ht3ry9i0	36	3	were	be	VBD
cord-104223-ht3ry9i0	36	4	then	then	RB
cord-104223-ht3ry9i0	36	5	step	step	NN
cord-104223-ht3ry9i0	36	6	-	-	HYPH
cord-104223-ht3ry9i0	36	7	wise	wise	RB
cord-104223-ht3ry9i0	36	8	dehydrated	dehydrate	VBN
cord-104223-ht3ry9i0	36	9	to	to	IN
cord-104223-ht3ry9i0	36	10	100	100	CD
cord-104223-ht3ry9i0	36	11	%	%	NN
cord-104223-ht3ry9i0	36	12	ethanol	ethanol	NN
cord-104223-ht3ry9i0	36	13	followed	follow	VBN
cord-104223-ht3ry9i0	36	14	by	by	IN
cord-104223-ht3ry9i0	36	15	propylene	propylene	NN
cord-104223-ht3ry9i0	36	16	oxide	oxide	NN
cord-104223-ht3ry9i0	36	17	before	before	IN
cord-104223-ht3ry9i0	36	18	infiltrating	infiltrate	VBG
cord-104223-ht3ry9i0	36	19	and	and	CC
cord-104223-ht3ry9i0	36	20	embedding	embed	VBG
cord-104223-ht3ry9i0	36	21	with	with	IN
cord-104223-ht3ry9i0	36	22	Epon	Epon	NNP
cord-104223-ht3ry9i0	36	23	-	-	HYPH
cord-104223-ht3ry9i0	36	24	Araldite	Araldite	NNP
cord-104223-ht3ry9i0	36	25	.	.	.
cord-104223-ht3ry9i0	37	1	After	after	IN
cord-104223-ht3ry9i0	37	2	polymerization	polymerization	NN
cord-104223-ht3ry9i0	37	3	,	,	,
cord-104223-ht3ry9i0	37	4	thin	thin	JJ
cord-104223-ht3ry9i0	37	5	sections	section	NNS
cord-104223-ht3ry9i0	37	6	(	(	-LRB-
cord-104223-ht3ry9i0	37	7	80	80	CD
cord-104223-ht3ry9i0	37	8	-	-	SYM
cord-104223-ht3ry9i0	37	9	100	100	CD
cord-104223-ht3ry9i0	37	10	nm	nm	NN
cord-104223-ht3ry9i0	37	11	)	)	-RRB-
cord-104223-ht3ry9i0	37	12	were	be	VBD
cord-104223-ht3ry9i0	37	13	cut	cut	VBN
cord-104223-ht3ry9i0	37	14	on	on	IN
cord-104223-ht3ry9i0	37	15	a	a	DT
cord-104223-ht3ry9i0	37	16	microtome	microtome	NN
cord-104223-ht3ry9i0	37	17	(	(	-LRB-
cord-104223-ht3ry9i0	37	18	Reichert	Reichert	NNP
cord-104223-ht3ry9i0	37	19	Jung	Jung	NNP
cord-104223-ht3ry9i0	37	20	,	,	,
cord-104223-ht3ry9i0	37	21	Vienna	Vienna	NNP
cord-104223-ht3ry9i0	37	22	,	,	,
cord-104223-ht3ry9i0	37	23	Austria	Austria	NNP
cord-104223-ht3ry9i0	37	24	)	)	-RRB-
cord-104223-ht3ry9i0	37	25	and	and	CC
cord-104223-ht3ry9i0	37	26	collected	collect	VBN
cord-104223-ht3ry9i0	37	27	on	on	IN
cord-104223-ht3ry9i0	37	28	formvar	formvar	NNS
cord-104223-ht3ry9i0	37	29	-	-	HYPH
cord-104223-ht3ry9i0	37	30	coated	coat	VBN
cord-104223-ht3ry9i0	37	31	nickel	nickel	NN
cord-104223-ht3ry9i0	37	32	grids	grid	NNS
cord-104223-ht3ry9i0	37	33	.	.	.
cord-104223-ht3ry9i0	38	1	The	the	DT
cord-104223-ht3ry9i0	38	2	grids	grid	NNS
cord-104223-ht3ry9i0	38	3	were	be	VBD
cord-104223-ht3ry9i0	38	4	then	then	RB
cord-104223-ht3ry9i0	38	5	lead	lead	JJ
cord-104223-ht3ry9i0	38	6	stained	stain	VBN
cord-104223-ht3ry9i0	38	7	,	,	,
cord-104223-ht3ry9i0	38	8	carbon	carbon	NN
cord-104223-ht3ry9i0	38	9	coated	coat	VBN
cord-104223-ht3ry9i0	38	10	,	,	,
cord-104223-ht3ry9i0	38	11	and	and	CC
cord-104223-ht3ry9i0	38	12	covered	cover	VBN
cord-104223-ht3ry9i0	38	13	with	with	IN
cord-104223-ht3ry9i0	38	14	emulsion	emulsion	NN
cord-104223-ht3ry9i0	38	15	L4	l4	NN
cord-104223-ht3ry9i0	38	16	;	;	:
cord-104223-ht3ry9i0	38	17	Ilford	Ilford	NNP
cord-104223-ht3ry9i0	38	18	Ltd.	Ltd.	NNP
cord-104223-ht3ry9i0	38	19	,	,	,
cord-104223-ht3ry9i0	38	20	Basildon	Basildon	NNP
cord-104223-ht3ry9i0	38	21	,	,	,
cord-104223-ht3ry9i0	38	22	Essex	Essex	NNP
cord-104223-ht3ry9i0	38	23	,	,	,
cord-104223-ht3ry9i0	38	24	England	England	NNP
cord-104223-ht3ry9i0	38	25	)	)	-RRB-
cord-104223-ht3ry9i0	38	26	using	use	VBG
cord-104223-ht3ry9i0	38	27	the	the	DT
cord-104223-ht3ry9i0	38	28	loop	loop	NN
cord-104223-ht3ry9i0	38	29	technique	technique	NN
cord-104223-ht3ry9i0	38	30	(	(	-LRB-
cord-104223-ht3ry9i0	38	31	Caro	Caro	NNP
cord-104223-ht3ry9i0	38	32	and	and	CC
cord-104223-ht3ry9i0	38	33	Van	Van	NNP
cord-104223-ht3ry9i0	38	34	Tubergen	Tubergen	NNP
cord-104223-ht3ry9i0	38	35	,	,	,
cord-104223-ht3ry9i0	38	36	1962	1962	CD
cord-104223-ht3ry9i0	38	37	;	;	:
cord-104223-ht3ry9i0	38	38	Caro	Caro	NNP
cord-104223-ht3ry9i0	38	39	,	,	,
cord-104223-ht3ry9i0	38	40	1969	1969	CD
cord-104223-ht3ry9i0	38	41	;	;	:
cord-104223-ht3ry9i0	38	42	Williams	Williams	NNP
cord-104223-ht3ry9i0	38	43	,	,	,
cord-104223-ht3ry9i0	38	44	1977	1977	CD
cord-104223-ht3ry9i0	38	45	)	)	-RRB-
cord-104223-ht3ry9i0	38	46	.	.	.
cord-104223-ht3ry9i0	39	1	The	the	DT
cord-104223-ht3ry9i0	39	2	emulsion	emulsion	NN
cord-104223-ht3ry9i0	39	3	was	be	VBD
cord-104223-ht3ry9i0	39	4	exposed	expose	VBN
cord-104223-ht3ry9i0	39	5	in	in	IN
cord-104223-ht3ry9i0	39	6	the	the	DT
cord-104223-ht3ry9i0	39	7	dark	dark	NN
cord-104223-ht3ry9i0	39	8	at	at	IN
cord-104223-ht3ry9i0	39	9	4	4	CD
cord-104223-ht3ry9i0	39	10	°	°	NN
cord-104223-ht3ry9i0	39	11	C	c	NN
cord-104223-ht3ry9i0	39	12	from	from	IN
cord-104223-ht3ry9i0	39	13	2	2	CD
cord-104223-ht3ry9i0	39	14	d	d	NN
cord-104223-ht3ry9i0	39	15	to	to	IN
cord-104223-ht3ry9i0	39	16	1	1	CD
cord-104223-ht3ry9i0	39	17	mo	mo	NN
cord-104223-ht3ry9i0	39	18	depending	depend	VBG
cord-104223-ht3ry9i0	39	19	on	on	IN
cord-104223-ht3ry9i0	39	20	the	the	DT
cord-104223-ht3ry9i0	39	21	experiment	experiment	NN
cord-104223-ht3ry9i0	39	22	and	and	CC
cord-104223-ht3ry9i0	39	23	then	then	RB
cord-104223-ht3ry9i0	39	24	developed	develop	VBN
cord-104223-ht3ry9i0	39	25	by	by	IN
cord-104223-ht3ry9i0	39	26	incubating	incubate	VBG
cord-104223-ht3ry9i0	39	27	in	in	IN
cord-104223-ht3ry9i0	39	28	Microdol	Microdol	NNP
cord-104223-ht3ry9i0	39	29	X	X	NNP
cord-104223-ht3ry9i0	39	30	(	(	-LRB-
cord-104223-ht3ry9i0	39	31	Eastman	Eastman	NNP
cord-104223-ht3ry9i0	39	32	Kodak	Kodak	NNP
cord-104223-ht3ry9i0	39	33	Co.	Co.	NNP
cord-104223-ht3ry9i0	39	34	,	,	,
cord-104223-ht3ry9i0	39	35	R	R	NNP
cord-104223-ht3ry9i0	39	36	~	~	NNP
cord-104223-ht3ry9i0	39	37	chester	chester	NNP
cord-104223-ht3ry9i0	39	38	,	,	,
cord-104223-ht3ry9i0	39	39	NY	NY	NNP
cord-104223-ht3ry9i0	39	40	;	;	:
cord-104223-ht3ry9i0	39	41	3	3	CD
cord-104223-ht3ry9i0	39	42	rain	rain	NN
cord-104223-ht3ry9i0	39	43	)	)	-RRB-
cord-104223-ht3ry9i0	39	44	,	,	,
cord-104223-ht3ry9i0	39	45	stopped	stop	VBD
cord-104223-ht3ry9i0	39	46	in	in	IN
cord-104223-ht3ry9i0	39	47	1	1	CD
cord-104223-ht3ry9i0	39	48	%	%	NN
cord-104223-ht3ry9i0	39	49	acetic	acetic	JJ
cord-104223-ht3ry9i0	39	50	acid	acid	NN
cord-104223-ht3ry9i0	39	51	,	,	,
cord-104223-ht3ry9i0	39	52	fixed	fix	VBN
cord-104223-ht3ry9i0	39	53	with	with	IN
cord-104223-ht3ry9i0	39	54	30	30	CD
cord-104223-ht3ry9i0	39	55	%	%	NN
cord-104223-ht3ry9i0	39	56	sodium	sodium	NN
cord-104223-ht3ry9i0	39	57	thiosulfate	thiosulfate	NN
cord-104223-ht3ry9i0	39	58	(	(	-LRB-
cord-104223-ht3ry9i0	39	59	3	3	CD
cord-104223-ht3ry9i0	39	60	rain	rain	NN
cord-104223-ht3ry9i0	39	61	)	)	-RRB-
cord-104223-ht3ry9i0	39	62	,	,	,
cord-104223-ht3ry9i0	39	63	and	and	CC
cord-104223-ht3ry9i0	39	64	washed	wash	VBN
cord-104223-ht3ry9i0	39	65	in	in	IN
cord-104223-ht3ry9i0	39	66	DvH20	dvh20	NN
cord-104223-ht3ry9i0	39	67	.	.	.
cord-104223-ht3ry9i0	40	1	Grids	grid	NNS
cord-104223-ht3ry9i0	40	2	were	be	VBD
cord-104223-ht3ry9i0	40	3	then	then	RB
cord-104223-ht3ry9i0	40	4	visualized	visualize	VBN
cord-104223-ht3ry9i0	40	5	using	use	VBG
cord-104223-ht3ry9i0	40	6	a	a	DT
cord-104223-ht3ry9i0	40	7	transmission	transmission	NN
cord-104223-ht3ry9i0	40	8	electron	electron	NN
cord-104223-ht3ry9i0	40	9	microscope	microscope	NN
cord-104223-ht3ry9i0	40	10	(	(	-LRB-
cord-104223-ht3ry9i0	40	11	410	410	CD
cord-104223-ht3ry9i0	40	12	;	;	:
cord-104223-ht3ry9i0	40	13	Philips	Philips	NNP
cord-104223-ht3ry9i0	40	14	Electronic	Electronic	NNP
cord-104223-ht3ry9i0	40	15	Instruments	Instruments	NNPS
cord-104223-ht3ry9i0	40	16	,	,	,
cord-104223-ht3ry9i0	40	17	Inc.	Inc.	NNP
cord-104223-ht3ry9i0	40	18	,	,	,
cord-104223-ht3ry9i0	40	19	Mahwah	Mahwah	NNP
cord-104223-ht3ry9i0	40	20	,	,	,
cord-104223-ht3ry9i0	40	21	NJ	NJ	NNP
cord-104223-ht3ry9i0	40	22	)	)	-RRB-
cord-104223-ht3ry9i0	40	23	.	.	.
cord-104223-ht3ry9i0	41	1	Micrographs	Micrographs	NNP
cord-104223-ht3ry9i0	41	2	were	be	VBD
cord-104223-ht3ry9i0	41	3	photographed	photograph	VBN
cord-104223-ht3ry9i0	41	4	at	at	IN
cord-104223-ht3ry9i0	41	5	16,900x	16,900x	CD
cord-104223-ht3ry9i0	41	6	and	and	CC
cord-104223-ht3ry9i0	41	7	then	then	RB
cord-104223-ht3ry9i0	41	8	printed	print	VBN
cord-104223-ht3ry9i0	41	9	to	to	TO
cord-104223-ht3ry9i0	41	10	give	give	VB
cord-104223-ht3ry9i0	41	11	a	a	DT
cord-104223-ht3ry9i0	41	12	final	final	JJ
cord-104223-ht3ry9i0	41	13	magnification	magnification	NN
cord-104223-ht3ry9i0	41	14	of	of	IN
cord-104223-ht3ry9i0	41	15	45,000x	45,000x	CD
cord-104223-ht3ry9i0	41	16	.	.	.
cord-104223-ht3ry9i0	42	1	This	this	DT
cord-104223-ht3ry9i0	42	2	size	size	NN
cord-104223-ht3ry9i0	42	3	was	be	VBD
cord-104223-ht3ry9i0	42	4	chosen	choose	VBN
cord-104223-ht3ry9i0	42	5	as	as	IN
cord-104223-ht3ry9i0	42	6	the	the	DT
cord-104223-ht3ry9i0	42	7	smallest	small	JJS
cord-104223-ht3ry9i0	42	8	magnification	magnification	NN
cord-104223-ht3ry9i0	42	9	that	that	IN
cord-104223-ht3ry9i0	42	10	small	small	JJ
cord-104223-ht3ry9i0	42	11	clear	clear	JJ
cord-104223-ht3ry9i0	42	12	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	42	13	around	around	IN
cord-104223-ht3ry9i0	42	14	the	the	DT
cord-104223-ht3ry9i0	42	15	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	42	16	apparatus	apparatus	NN
cord-104223-ht3ry9i0	42	17	are	be	VBP
cord-104223-ht3ry9i0	42	18	clearly	clearly	RB
cord-104223-ht3ry9i0	42	19	visible	visible	JJ
cord-104223-ht3ry9i0	42	20	.	.	.
cord-104223-ht3ry9i0	43	1	Pictures	picture	NNS
cord-104223-ht3ry9i0	43	2	were	be	VBD
cord-104223-ht3ry9i0	43	3	not	not	RB
cord-104223-ht3ry9i0	43	4	taken	take	VBN
cord-104223-ht3ry9i0	43	5	at	at	IN
cord-104223-ht3ry9i0	43	6	grid	grid	NN
cord-104223-ht3ry9i0	43	7	coordinates	coordinate	NNS
cord-104223-ht3ry9i0	43	8	but	but	CC
cord-104223-ht3ry9i0	43	9	rather	rather	RB
cord-104223-ht3ry9i0	43	10	over	over	IN
cord-104223-ht3ry9i0	43	11	concentrations	concentration	NNS
cord-104223-ht3ry9i0	43	12	of	of	IN
cord-104223-ht3ry9i0	43	13	grains	grain	NNS
cord-104223-ht3ry9i0	43	14	.	.	.
cord-104223-ht3ry9i0	44	1	This	this	DT
cord-104223-ht3ry9i0	44	2	was	be	VBD
cord-104223-ht3ry9i0	44	3	necessary	necessary	JJ
cord-104223-ht3ry9i0	44	4	due	due	IN
cord-104223-ht3ry9i0	44	5	to	to	IN
cord-104223-ht3ry9i0	44	6	the	the	DT
cord-104223-ht3ry9i0	44	7	large	large	JJ
cord-104223-ht3ry9i0	44	8	size	size	NN
cord-104223-ht3ry9i0	44	9	of	of	IN
cord-104223-ht3ry9i0	44	10	the	the	DT
cord-104223-ht3ry9i0	44	11	bag	bag	NN
cord-104223-ht3ry9i0	44	12	cells	cell	NNS
cord-104223-ht3ry9i0	44	13	(	(	-LRB-
cord-104223-ht3ry9i0	44	14	50/~M	50/~m	CD
cord-104223-ht3ry9i0	44	15	Table	table	NN
cord-104223-ht3ry9i0	44	16	I	-PRON-	PRP
cord-104223-ht3ry9i0	44	17	.	.	.
cord-104223-ht3ry9i0	45	1	Quantitation	quantitation	NN
cord-104223-ht3ry9i0	45	2	of	of	IN
cord-104223-ht3ry9i0	45	3	EM	EM	NNP
cord-104223-ht3ry9i0	45	4	Autoradiography	Autoradiography	NNP
cord-104223-ht3ry9i0	45	5	in	in	IN
cord-104223-ht3ry9i0	45	6	diameter	diameter	NN
cord-104223-ht3ry9i0	45	7	)	)	-RRB-
cord-104223-ht3ry9i0	45	8	and	and	CC
cord-104223-ht3ry9i0	45	9	the	the	DT
cord-104223-ht3ry9i0	45	10	small	small	JJ
cord-104223-ht3ry9i0	45	11	area	area	NN
cord-104223-ht3ry9i0	45	12	of	of	IN
cord-104223-ht3ry9i0	45	13	the	the	DT
cord-104223-ht3ry9i0	45	14	cells	cell	NNS
cord-104223-ht3ry9i0	45	15	in	in	IN
cord-104223-ht3ry9i0	45	16	which	which	WDT
cord-104223-ht3ry9i0	45	17	one	one	PRP
cord-104223-ht3ry9i0	45	18	could	could	MD
cord-104223-ht3ry9i0	45	19	find	find	VB
cord-104223-ht3ry9i0	45	20	grains	grain	NNS
cord-104223-ht3ry9i0	45	21	.	.	.
cord-104223-ht3ry9i0	46	1	Therefore	therefore	RB
cord-104223-ht3ry9i0	46	2	,	,	,
cord-104223-ht3ry9i0	46	3	all	all	DT
cord-104223-ht3ry9i0	46	4	results	result	NNS
cord-104223-ht3ry9i0	46	5	are	be	VBP
cord-104223-ht3ry9i0	46	6	given	give	VBN
cord-104223-ht3ry9i0	46	7	in	in	IN
cord-104223-ht3ry9i0	46	8	percentage	percentage	NN
cord-104223-ht3ry9i0	46	9	of	of	IN
cord-104223-ht3ry9i0	46	10	grains	grain	NNS
cord-104223-ht3ry9i0	46	11	in	in	IN
cord-104223-ht3ry9i0	46	12	each	each	DT
cord-104223-ht3ry9i0	46	13	compartment	compartment	NN
cord-104223-ht3ry9i0	46	14	rather	rather	RB
cord-104223-ht3ry9i0	46	15	than	than	IN
cord-104223-ht3ry9i0	46	16	density	density	NN
cord-104223-ht3ry9i0	46	17	of	of	IN
cord-104223-ht3ry9i0	46	18	radioactivity	radioactivity	NN
cord-104223-ht3ry9i0	46	19	in	in	IN
cord-104223-ht3ry9i0	46	20	each	each	DT
cord-104223-ht3ry9i0	46	21	compartment	compartment	NN
cord-104223-ht3ry9i0	46	22	.	.	.
cord-104223-ht3ry9i0	47	1	The	the	DT
cord-104223-ht3ry9i0	47	2	micrographs	micrograph	NNS
cord-104223-ht3ry9i0	47	3	were	be	VBD
cord-104223-ht3ry9i0	47	4	digitized	digitize	VBN
cord-104223-ht3ry9i0	47	5	(	(	-LRB-
cord-104223-ht3ry9i0	47	6	GP7	GP7	NNP
cord-104223-ht3ry9i0	47	7	digitizer	digitizer	NN
cord-104223-ht3ry9i0	47	8	;	;	:
cord-104223-ht3ry9i0	47	9	Science	Science	NNP
cord-104223-ht3ry9i0	47	10	Accessories	Accessories	NNP
cord-104223-ht3ry9i0	47	11	Corp.	Corp.	NNP
cord-104223-ht3ry9i0	47	12	,	,	,
cord-104223-ht3ry9i0	47	13	Southport	Southport	NNP
cord-104223-ht3ry9i0	47	14	,	,	,
cord-104223-ht3ry9i0	47	15	CT	CT	NNP
cord-104223-ht3ry9i0	47	16	)	)	-RRB-
cord-104223-ht3ry9i0	47	17	and	and	CC
cord-104223-ht3ry9i0	47	18	analyzed	analyze	VBD
cord-104223-ht3ry9i0	47	19	using	use	VBG
cord-104223-ht3ry9i0	47	20	a	a	DT
cord-104223-ht3ry9i0	47	21	computer	computer	NN
cord-104223-ht3ry9i0	47	22	-	-	HYPH
cord-104223-ht3ry9i0	47	23	implemented	implement	VBN
cord-104223-ht3ry9i0	47	24	maximum	maximum	JJ
cord-104223-ht3ry9i0	47	25	likelihood	likelihood	NN
cord-104223-ht3ry9i0	47	26	algorithm	algorithm	NN
cord-104223-ht3ry9i0	47	27	(	(	-LRB-
cord-104223-ht3ry9i0	47	28	Miller	Miller	NNP
cord-104223-ht3ry9i0	47	29	et	et	NNP
cord-104223-ht3ry9i0	47	30	al	al	NNP
cord-104223-ht3ry9i0	47	31	.	.	NNP
cord-104223-ht3ry9i0	47	32	,	,	,
cord-104223-ht3ry9i0	47	33	1985	1985	CD
cord-104223-ht3ry9i0	47	34	)	)	-RRB-
cord-104223-ht3ry9i0	47	35	.	.	.
cord-104223-ht3ry9i0	48	1	An	an	DT
cord-104223-ht3ry9i0	48	2	important	important	JJ
cord-104223-ht3ry9i0	48	3	parameter	parameter	NN
cord-104223-ht3ry9i0	48	4	in	in	IN
cord-104223-ht3ry9i0	48	5	this	this	DT
cord-104223-ht3ry9i0	48	6	program	program	NN
cord-104223-ht3ry9i0	48	7	is	be	VBZ
cord-104223-ht3ry9i0	48	8	the	the	DT
cord-104223-ht3ry9i0	48	9	approximate	approximate	JJ
cord-104223-ht3ry9i0	48	10	error	error	NN
cord-104223-ht3ry9i0	48	11	due	due	IN
cord-104223-ht3ry9i0	48	12	to	to	IN
cord-104223-ht3ry9i0	48	13	the	the	DT
cord-104223-ht3ry9i0	48	14	spread	spread	NN
cord-104223-ht3ry9i0	48	15	of	of	IN
cord-104223-ht3ry9i0	48	16	radioactivity	radioactivity	NN
cord-104223-ht3ry9i0	48	17	,	,	,
cord-104223-ht3ry9i0	48	18	which	which	WDT
cord-104223-ht3ry9i0	48	19	depends	depend	VBZ
cord-104223-ht3ry9i0	48	20	on	on	IN
cord-104223-ht3ry9i0	48	21	the	the	DT
cord-104223-ht3ry9i0	48	22	thickness	thickness	NN
cord-104223-ht3ry9i0	48	23	of	of	IN
cord-104223-ht3ry9i0	48	24	the	the	DT
cord-104223-ht3ry9i0	48	25	section	section	NN
cord-104223-ht3ry9i0	48	26	and	and	CC
cord-104223-ht3ry9i0	48	27	the	the	DT
cord-104223-ht3ry9i0	48	28	emulsion	emulsion	NN
cord-104223-ht3ry9i0	48	29	.	.	.
cord-104223-ht3ry9i0	49	1	We	-PRON-	PRP
cord-104223-ht3ry9i0	49	2	calculated	calculate	VBD
cord-104223-ht3ry9i0	49	3	all	all	DT
cord-104223-ht3ry9i0	49	4	time	time	NN
cord-104223-ht3ry9i0	49	5	points	point	VBZ
cord-104223-ht3ry9i0	49	6	at	at	IN
cord-104223-ht3ry9i0	49	7	half	half	JJ
cord-104223-ht3ry9i0	49	8	-	-	HYPH
cord-104223-ht3ry9i0	49	9	distance	distance	NN
cord-104223-ht3ry9i0	49	10	(	(	-LRB-
cord-104223-ht3ry9i0	49	11	HD	hd	NN
cord-104223-ht3ry9i0	49	12	)	)	-RRB-
cord-104223-ht3ry9i0	49	13	values	value	NNS
cord-104223-ht3ry9i0	49	14	(	(	-LRB-
cord-104223-ht3ry9i0	49	15	Saltpeter	Saltpeter	NNP
cord-104223-ht3ry9i0	49	16	and	and	CC
cord-104223-ht3ry9i0	49	17	Bachmann	Bachmann	NNP
cord-104223-ht3ry9i0	49	18	,	,	,
cord-104223-ht3ry9i0	49	19	1972	1972	CD
cord-104223-ht3ry9i0	49	20	)	)	-RRB-
cord-104223-ht3ry9i0	49	21	of	of	IN
cord-104223-ht3ry9i0	49	22	165	165	CD
cord-104223-ht3ry9i0	49	23	,	,	,
cord-104223-ht3ry9i0	49	24	190	190	CD
cord-104223-ht3ry9i0	49	25	,	,	,
cord-104223-ht3ry9i0	49	26	and	and	CC
cord-104223-ht3ry9i0	49	27	230	230	CD
cord-104223-ht3ry9i0	49	28	am	be	VBP
cord-104223-ht3ry9i0	49	29	.	.	.
cord-104223-ht3ry9i0	50	1	The	the	DT
cord-104223-ht3ry9i0	50	2	calculations	calculation	NNS
cord-104223-ht3ry9i0	50	3	are	be	VBP
cord-104223-ht3ry9i0	50	4	fairly	fairly	RB
cord-104223-ht3ry9i0	50	5	insensitive	insensitive	JJ
cord-104223-ht3ry9i0	50	6	to	to	IN
cord-104223-ht3ry9i0	50	7	this	this	DT
cord-104223-ht3ry9i0	50	8	parameter	parameter	NN
cord-104223-ht3ry9i0	50	9	,	,	,
cord-104223-ht3ry9i0	50	10	and	and	CC
cord-104223-ht3ry9i0	50	11	the	the	DT
cord-104223-ht3ry9i0	50	12	data	datum	NNS
cord-104223-ht3ry9i0	50	13	in	in	IN
cord-104223-ht3ry9i0	50	14	Table	table	NN
cord-104223-ht3ry9i0	50	15	I	-PRON-	PRP
cord-104223-ht3ry9i0	50	16	are	be	VBP
cord-104223-ht3ry9i0	50	17	calculated	calculate	VBN
cord-104223-ht3ry9i0	50	18	with	with	IN
cord-104223-ht3ry9i0	50	19	an	an	DT
cord-104223-ht3ry9i0	50	20	HD	hd	NN
cord-104223-ht3ry9i0	50	21	of	of	IN
cord-104223-ht3ry9i0	50	22	190	190	CD
cord-104223-ht3ry9i0	50	23	run	run	NN
cord-104223-ht3ry9i0	50	24	,	,	,
cord-104223-ht3ry9i0	50	25	as	as	IN
cord-104223-ht3ry9i0	50	26	this	this	DT
cord-104223-ht3ry9i0	50	27	value	value	NN
cord-104223-ht3ry9i0	50	28	matched	match	VBD
cord-104223-ht3ry9i0	50	29	our	-PRON-	PRP$
cord-104223-ht3ry9i0	50	30	estimates	estimate	NNS
cord-104223-ht3ry9i0	50	31	for	for	IN
cord-104223-ht3ry9i0	50	32	section	section	NN
cord-104223-ht3ry9i0	50	33	and	and	CC
cord-104223-ht3ry9i0	50	34	emulsion	emulsion	NN
cord-104223-ht3ry9i0	50	35	thickness	thickness	NN
cord-104223-ht3ry9i0	50	36	.	.	.
cord-104223-ht3ry9i0	51	1	The	the	DT
cord-104223-ht3ry9i0	51	2	largest	large	JJS
cord-104223-ht3ry9i0	51	3	variations	variation	NNS
cord-104223-ht3ry9i0	51	4	observed	observe	VBN
cord-104223-ht3ry9i0	51	5	at	at	IN
cord-104223-ht3ry9i0	51	6	different	different	JJ
cord-104223-ht3ry9i0	51	7	HD	hd	NN
cord-104223-ht3ry9i0	51	8	values	value	NNS
cord-104223-ht3ry9i0	51	9	occur	occur	VBP
cord-104223-ht3ry9i0	51	10	between	between	IN
cord-104223-ht3ry9i0	51	11	the	the	DT
cord-104223-ht3ry9i0	51	12	cytoplasm	cytoplasm	NN
cord-104223-ht3ry9i0	51	13	,	,	,
cord-104223-ht3ry9i0	51	14	ER	ER	NNP
cord-104223-ht3ry9i0	51	15	,	,	,
cord-104223-ht3ry9i0	51	16	and	and	CC
cord-104223-ht3ry9i0	51	17	small	small	JJ
cord-104223-ht3ry9i0	51	18	mature	mature	JJ
cord-104223-ht3ry9i0	51	19	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	51	20	.	.	.
cord-104223-ht3ry9i0	52	1	All	all	DT
cord-104223-ht3ry9i0	52	2	of	of	IN
cord-104223-ht3ry9i0	52	3	these	these	DT
cord-104223-ht3ry9i0	52	4	compartments	compartment	NNS
cord-104223-ht3ry9i0	52	5	have	have	VBP
cord-104223-ht3ry9i0	52	6	large	large	JJ
cord-104223-ht3ry9i0	52	7	areas	area	NNS
cord-104223-ht3ry9i0	52	8	and	and	CC
cord-104223-ht3ry9i0	52	9	low	low	JJ
cord-104223-ht3ry9i0	52	10	densities	density	NNS
cord-104223-ht3ry9i0	52	11	and	and	CC
cord-104223-ht3ry9i0	52	12	are	be	VBP
cord-104223-ht3ry9i0	52	13	situated	situate	VBN
cord-104223-ht3ry9i0	52	14	in	in	IN
cord-104223-ht3ry9i0	52	15	close	close	JJ
cord-104223-ht3ry9i0	52	16	proximity	proximity	NN
cord-104223-ht3ry9i0	52	17	to	to	IN
cord-104223-ht3ry9i0	52	18	each	each	DT
cord-104223-ht3ry9i0	52	19	other	other	JJ
cord-104223-ht3ry9i0	52	20	,	,	,
cord-104223-ht3ry9i0	52	21	making	make	VBG
cord-104223-ht3ry9i0	52	22	it	-PRON-	PRP
cord-104223-ht3ry9i0	52	23	difficult	difficult	JJ
cord-104223-ht3ry9i0	52	24	to	to	TO
cord-104223-ht3ry9i0	52	25	asign	asign	VB
cord-104223-ht3ry9i0	52	26	counts	count	NNS
cord-104223-ht3ry9i0	52	27	between	between	IN
cord-104223-ht3ry9i0	52	28	these	these	DT
cord-104223-ht3ry9i0	52	29	compartments	compartment	NNS
cord-104223-ht3ry9i0	52	30	.	.	.
cord-104223-ht3ry9i0	53	1	The	the	DT
cord-104223-ht3ry9i0	53	2	largest	large	JJS
cord-104223-ht3ry9i0	53	3	change	change	NN
cord-104223-ht3ry9i0	53	4	is	be	VBZ
cord-104223-ht3ry9i0	53	5	seen	see	VBN
cord-104223-ht3ry9i0	53	6	at	at	IN
cord-104223-ht3ry9i0	53	7	the	the	DT
cord-104223-ht3ry9i0	53	8	Ile	Ile	NNP
cord-104223-ht3ry9i0	53	9	30-rain	30-rain	CD
cord-104223-ht3ry9i0	53	10	pulse	pulse	NN
cord-104223-ht3ry9i0	53	11	plus	plus	CC
cord-104223-ht3ry9i0	53	12	4-h	4-h	CD
cord-104223-ht3ry9i0	53	13	chase	chase	NN
cord-104223-ht3ry9i0	53	14	time	time	NN
cord-104223-ht3ry9i0	53	15	point	point	NN
cord-104223-ht3ry9i0	53	16	,	,	,
cord-104223-ht3ry9i0	53	17	when	when	WRB
cord-104223-ht3ry9i0	53	18	,	,	,
cord-104223-ht3ry9i0	53	19	with	with	IN
cord-104223-ht3ry9i0	53	20	an	an	DT
cord-104223-ht3ry9i0	53	21	HD	hd	NN
cord-104223-ht3ry9i0	53	22	of	of	IN
cord-104223-ht3ry9i0	53	23	230	230	CD
cord-104223-ht3ry9i0	53	24	am	am	NN
cord-104223-ht3ry9i0	53	25	,	,	,
cord-104223-ht3ry9i0	53	26	the	the	DT
cord-104223-ht3ry9i0	53	27	percentage	percentage	NN
cord-104223-ht3ry9i0	53	28	of	of	IN
cord-104223-ht3ry9i0	53	29	counts	count	NNS
cord-104223-ht3ry9i0	53	30	in	in	IN
cord-104223-ht3ry9i0	53	31	small	small	JJ
cord-104223-ht3ry9i0	53	32	mature	mature	JJ
cord-104223-ht3ry9i0	53	33	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	53	34	and	and	CC
cord-104223-ht3ry9i0	53	35	cytoplasm	cytoplasm	NN
cord-104223-ht3ry9i0	53	36	are	be	VBP
cord-104223-ht3ry9i0	53	37	34.3	34.3	CD
cord-104223-ht3ry9i0	53	38	and	and	CC
cord-104223-ht3ry9i0	53	39	21.3	21.3	CD
cord-104223-ht3ry9i0	53	40	%	%	NN
cord-104223-ht3ry9i0	53	41	,	,	,
cord-104223-ht3ry9i0	53	42	respectively	respectively	RB
cord-104223-ht3ry9i0	53	43	,	,	,
cord-104223-ht3ry9i0	53	44	as	as	IN
cord-104223-ht3ry9i0	53	45	opposed	oppose	VBN
cord-104223-ht3ry9i0	53	46	to	to	IN
cord-104223-ht3ry9i0	53	47	17.6	17.6	CD
cord-104223-ht3ry9i0	53	48	and	and	CC
cord-104223-ht3ry9i0	53	49	55.4	55.4	CD
cord-104223-ht3ry9i0	53	50	%	%	NN
cord-104223-ht3ry9i0	53	51	with	with	IN
cord-104223-ht3ry9i0	53	52	an	an	DT
cord-104223-ht3ry9i0	53	53	HD	hd	NN
cord-104223-ht3ry9i0	53	54	of	of	IN
cord-104223-ht3ry9i0	53	55	165	165	CD
cord-104223-ht3ry9i0	53	56	am	am	NN
cord-104223-ht3ry9i0	53	57	.	.	.
cord-104223-ht3ry9i0	54	1	All	all	DT
cord-104223-ht3ry9i0	54	2	other	other	JJ
cord-104223-ht3ry9i0	54	3	changes	change	NNS
cord-104223-ht3ry9i0	54	4	were	be	VBD
cord-104223-ht3ry9i0	54	5	minor	minor	JJ
cord-104223-ht3ry9i0	54	6	in	in	IN
cord-104223-ht3ry9i0	54	7	comparison	comparison	NN
cord-104223-ht3ry9i0	54	8	,	,	,
cord-104223-ht3ry9i0	54	9	and	and	CC
cord-104223-ht3ry9i0	54	10	in	in	IN
cord-104223-ht3ry9i0	54	11	the	the	DT
cord-104223-ht3ry9i0	54	12	compartments	compartment	NNS
cord-104223-ht3ry9i0	54	13	important	important	JJ
cord-104223-ht3ry9i0	54	14	in	in	IN
cord-104223-ht3ry9i0	54	15	these	these	DT
cord-104223-ht3ry9i0	54	16	studies	study	NNS
cord-104223-ht3ry9i0	54	17	-	-	:
cord-104223-ht3ry9i0	54	18	small	small	JJ
cord-104223-ht3ry9i0	54	19	and	and	CC
cord-104223-ht3ry9i0	54	20	large	large	JJ
cord-104223-ht3ry9i0	54	21	immature	immature	JJ
cord-104223-ht3ry9i0	54	22	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	54	23	,	,	,
cord-104223-ht3ry9i0	54	24	clear	clear	JJ
cord-104223-ht3ry9i0	54	25	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	54	26	,	,	,
cord-104223-ht3ry9i0	54	27	and	and	CC
cord-104223-ht3ry9i0	54	28	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	54	29	apparatus	apparatus	NN
cord-104223-ht3ry9i0	54	30	-	-	:
cord-104223-ht3ry9i0	54	31	the	the	DT
cord-104223-ht3ry9i0	54	32	results	result	NNS
cord-104223-ht3ry9i0	54	33	between	between	IN
cord-104223-ht3ry9i0	54	34	calculations	calculation	NNS
cord-104223-ht3ry9i0	54	35	at	at	IN
cord-104223-ht3ry9i0	54	36	three	three	CD
cord-104223-ht3ry9i0	54	37	HD	hd	NN
cord-104223-ht3ry9i0	54	38	values	value	NNS
cord-104223-ht3ry9i0	54	39	differ	differ	VBP
cord-104223-ht3ry9i0	54	40	by	by	IN
cord-104223-ht3ry9i0	54	41	no	no	DT
cord-104223-ht3ry9i0	54	42	more	more	JJR
cord-104223-ht3ry9i0	54	43	than	than	IN
cord-104223-ht3ry9i0	54	44	5	5	CD
cord-104223-ht3ry9i0	54	45	%	%	NN
cord-104223-ht3ry9i0	54	46	in	in	IN
cord-104223-ht3ry9i0	54	47	any	any	DT
cord-104223-ht3ry9i0	54	48	experiment	experiment	NN
cord-104223-ht3ry9i0	54	49	.	.	.
cord-104223-ht3ry9i0	55	1	There	there	EX
cord-104223-ht3ry9i0	55	2	were	be	VBD
cord-104223-ht3ry9i0	55	3	nine	nine	CD
cord-104223-ht3ry9i0	55	4	compartments	compartment	NNS
cord-104223-ht3ry9i0	55	5	entered	enter	VBN
cord-104223-ht3ry9i0	55	6	during	during	IN
cord-104223-ht3ry9i0	55	7	digitization	digitization	NN
cord-104223-ht3ry9i0	55	8	of	of	IN
cord-104223-ht3ry9i0	55	9	the	the	DT
cord-104223-ht3ry9i0	55	10	micrograph	micrograph	NN
cord-104223-ht3ry9i0	55	11	(	(	-LRB-
cord-104223-ht3ry9i0	55	12	ER	ER	NNP
cord-104223-ht3ry9i0	55	13	,	,	,
cord-104223-ht3ry9i0	55	14	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	55	15	apparatus	apparatus	NN
cord-104223-ht3ry9i0	55	16	,	,	,
cord-104223-ht3ry9i0	55	17	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	55	18	-	-	HYPH
cord-104223-ht3ry9i0	55	19	associated	associate	VBN
cord-104223-ht3ry9i0	55	20	sacs	sac	NNS
cord-104223-ht3ry9i0	55	21	[	[	-LRB-
cord-104223-ht3ry9i0	55	22	usually	usually	RB
cord-104223-ht3ry9i0	55	23	situated	situate	VBN
cord-104223-ht3ry9i0	55	24	on	on	IN
cord-104223-ht3ry9i0	55	25	the	the	DT
cord-104223-ht3ry9i0	55	26	cis	cis	NNP
cord-104223-ht3ry9i0	55	27	side	side	NN
cord-104223-ht3ry9i0	55	28	of	of	IN
cord-104223-ht3ry9i0	55	29	the	the	DT
cord-104223-ht3ry9i0	55	30	Goigi	Goigi	NNP
cord-104223-ht3ry9i0	55	31	apparatus	apparatus	NN
cord-104223-ht3ry9i0	55	32	]	]	-RRB-
cord-104223-ht3ry9i0	55	33	,	,	,
cord-104223-ht3ry9i0	55	34	DCVs	dcv	NNS
cord-104223-ht3ry9i0	55	35	,	,	,
cord-104223-ht3ry9i0	55	36	immature	immature	JJ
cord-104223-ht3ry9i0	55	37	DCVs	dcv	NNS
cord-104223-ht3ry9i0	55	38	,	,	,
cord-104223-ht3ry9i0	55	39	clear	clear	JJ
cord-104223-ht3ry9i0	55	40	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	55	41	,	,	,
cord-104223-ht3ry9i0	55	42	mitochondria	mitochondrion	NNS
cord-104223-ht3ry9i0	55	43	,	,	,
cord-104223-ht3ry9i0	55	44	lysosomes	lysosome	NNS
cord-104223-ht3ry9i0	55	45	,	,	,
cord-104223-ht3ry9i0	55	46	and	and	CC
cord-104223-ht3ry9i0	55	47	nucleus	nucleus	NN
cord-104223-ht3ry9i0	55	48	)	)	-RRB-
cord-104223-ht3ry9i0	55	49	.	.	.
cord-104223-ht3ry9i0	56	1	All	all	DT
cord-104223-ht3ry9i0	56	2	nonlabeled	nonlabeled	JJ
cord-104223-ht3ry9i0	56	3	parts	part	NNS
cord-104223-ht3ry9i0	56	4	of	of	IN
cord-104223-ht3ry9i0	56	5	the	the	DT
cord-104223-ht3ry9i0	56	6	micrographs	micrograph	NNS
cord-104223-ht3ry9i0	56	7	defaulted	default	VBD
cord-104223-ht3ry9i0	56	8	to	to	TO
cord-104223-ht3ry9i0	56	9	cytoplasm	cytoplasm	VB
cord-104223-ht3ry9i0	56	10	.	.	.
cord-104223-ht3ry9i0	57	1	Mature	mature	JJ
cord-104223-ht3ry9i0	57	2	and	and	CC
cord-104223-ht3ry9i0	57	3	immature	immature	JJ
cord-104223-ht3ry9i0	57	4	DCVs	dcv	NNS
cord-104223-ht3ry9i0	57	5	were	be	VBD
cord-104223-ht3ry9i0	57	6	then	then	RB
cord-104223-ht3ry9i0	57	7	divided	divide	VBN
cord-104223-ht3ry9i0	57	8	into	into	IN
cord-104223-ht3ry9i0	57	9	small	small	JJ
cord-104223-ht3ry9i0	57	10	and	and	CC
cord-104223-ht3ry9i0	57	11	large	large	JJ
cord-104223-ht3ry9i0	57	12	classes	class	NNS
cord-104223-ht3ry9i0	57	13	using	use	VBG
cord-104223-ht3ry9i0	57	14	a	a	DT
cord-104223-ht3ry9i0	57	15	size	size	NN
cord-104223-ht3ry9i0	57	16	cutoff	cutoff	NN
cord-104223-ht3ry9i0	57	17	(	(	-LRB-
cord-104223-ht3ry9i0	57	18	area	area	NN
cord-104223-ht3ry9i0	57	19	=	=	SYM
cord-104223-ht3ry9i0	57	20	49,000	49,000	CD
cord-104223-ht3ry9i0	57	21	nm	nm	SYM
cord-104223-ht3ry9i0	57	22	2	2	CD
cord-104223-ht3ry9i0	57	23	,	,	,
cord-104223-ht3ry9i0	57	24	based	base	VBN
cord-104223-ht3ry9i0	57	25	on	on	IN
cord-104223-ht3ry9i0	57	26	a	a	DT
cord-104223-ht3ry9i0	57	27	diameter	diameter	NN
cord-104223-ht3ry9i0	57	28	of	of	IN
cord-104223-ht3ry9i0	57	29	250	250	CD
cord-104223-ht3ry9i0	57	30	nm	nm	NN
cord-104223-ht3ry9i0	57	31	;	;	:
cord-104223-ht3ry9i0	57	32	Fisher	Fisher	NNP
cord-104223-ht3ry9i0	57	33	et	et	NNP
cord-104223-ht3ry9i0	57	34	al	al	NNP
cord-104223-ht3ry9i0	57	35	.	.	NNP
cord-104223-ht3ry9i0	57	36	,	,	,
cord-104223-ht3ry9i0	57	37	1988	1988	CD
cord-104223-ht3ry9i0	57	38	)	)	-RRB-
cord-104223-ht3ry9i0	57	39	to	to	TO
cord-104223-ht3ry9i0	57	40	make	make	VB
cord-104223-ht3ry9i0	57	41	a	a	DT
cord-104223-ht3ry9i0	57	42	total	total	NN
cord-104223-ht3ry9i0	57	43	of	of	IN
cord-104223-ht3ry9i0	57	44	12	12	CD
cord-104223-ht3ry9i0	57	45	compartments	compartment	NNS
cord-104223-ht3ry9i0	57	46	.	.	.
cord-104223-ht3ry9i0	58	1	The	the	DT
cord-104223-ht3ry9i0	58	2	areas	area	NNS
cord-104223-ht3ry9i0	58	3	of	of	IN
cord-104223-ht3ry9i0	58	4	labeled	label	VBN
cord-104223-ht3ry9i0	58	5	(	(	-LRB-
cord-104223-ht3ry9i0	58	6	center	center	NN
cord-104223-ht3ry9i0	58	7	of	of	IN
cord-104223-ht3ry9i0	58	8	at	at	RB
cord-104223-ht3ry9i0	58	9	least	least	RBS
cord-104223-ht3ry9i0	58	10	one	one	CD
cord-104223-ht3ry9i0	58	11	grain	grain	NN
cord-104223-ht3ry9i0	58	12	within	within	IN
cord-104223-ht3ry9i0	58	13	the	the	DT
cord-104223-ht3ry9i0	58	14	vesicle	vesicle	NN
cord-104223-ht3ry9i0	58	15	)	)	-RRB-
cord-104223-ht3ry9i0	58	16	and	and	CC
cord-104223-ht3ry9i0	58	17	unlabeled	unlabeled	JJ
cord-104223-ht3ry9i0	58	18	large	large	JJ
cord-104223-ht3ry9i0	58	19	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	58	20	were	be	VBD
cord-104223-ht3ry9i0	58	21	also	also	RB
cord-104223-ht3ry9i0	58	22	calculated	calculate	VBN
cord-104223-ht3ry9i0	58	23	to	to	TO
cord-104223-ht3ry9i0	58	24	determine	determine	VB
cord-104223-ht3ry9i0	58	25	if	if	IN
cord-104223-ht3ry9i0	58	26	Phe	Phe	NNP
cord-104223-ht3ry9i0	58	27	-	-	HYPH
cord-104223-ht3ry9i0	58	28	labeled	label	VBN
cord-104223-ht3ry9i0	58	29	small	small	JJ
cord-104223-ht3ry9i0	58	30	immature	immature	JJ
cord-104223-ht3ry9i0	58	31	DCVs	dcv	NNS
cord-104223-ht3ry9i0	58	32	gradually	gradually	RB
cord-104223-ht3ry9i0	58	33	increased	increase	VBD
cord-104223-ht3ry9i0	58	34	in	in	IN
cord-104223-ht3ry9i0	58	35	size	size	NN
cord-104223-ht3ry9i0	58	36	to	to	TO
cord-104223-ht3ry9i0	58	37	form	form	VB
cord-104223-ht3ry9i0	58	38	large	large	JJ
cord-104223-ht3ry9i0	58	39	Phe	phe	NN
cord-104223-ht3ry9i0	58	40	-	-	HYPH
cord-104223-ht3ry9i0	58	41	labeled	label	VBN
cord-104223-ht3ry9i0	58	42	immature	immature	JJ
cord-104223-ht3ry9i0	58	43	DCVs	dcv	NNS
cord-104223-ht3ry9i0	58	44	.	.	.
cord-104223-ht3ry9i0	59	1	At	at	IN
cord-104223-ht3ry9i0	59	2	the	the	DT
cord-104223-ht3ry9i0	59	3	earliest	early	JJS
cord-104223-ht3ry9i0	59	4	time	time	NN
cord-104223-ht3ry9i0	59	5	point	point	NN
cord-104223-ht3ry9i0	59	6	that	that	IN
cord-104223-ht3ry9i0	59	7	significant	significant	JJ
cord-104223-ht3ry9i0	59	8	radioactivity	radioactivity	NN
cord-104223-ht3ry9i0	59	9	is	be	VBZ
cord-104223-ht3ry9i0	59	10	observed	observe	VBN
cord-104223-ht3ry9i0	59	11	in	in	IN
cord-104223-ht3ry9i0	59	12	large	large	JJ
cord-104223-ht3ry9i0	59	13	immature	immature	JJ
cord-104223-ht3ry9i0	59	14	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	59	15	(	(	-LRB-
cord-104223-ht3ry9i0	59	16	Phe	Phe	NNP
cord-104223-ht3ry9i0	59	17	5-rain	5-rain	CD
cord-104223-ht3ry9i0	59	18	pulse	pulse	NN
cord-104223-ht3ry9i0	59	19	plus	plus	IN
cord-104223-ht3ry9i0	59	20	45rain	45rain	CD
cord-104223-ht3ry9i0	59	21	chase	chase	NNP
cord-104223-ht3ry9i0	59	22	)	)	-RRB-
cord-104223-ht3ry9i0	59	23	,	,	,
cord-104223-ht3ry9i0	59	24	the	the	DT
cord-104223-ht3ry9i0	59	25	average	average	JJ
cord-104223-ht3ry9i0	59	26	area	area	NN
cord-104223-ht3ry9i0	59	27	of	of	IN
cord-104223-ht3ry9i0	59	28	labeled	label	VBN
cord-104223-ht3ry9i0	59	29	large	large	JJ
cord-104223-ht3ry9i0	59	30	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	59	31	was	be	VBD
cord-104223-ht3ry9i0	59	32	actually	actually	RB
cord-104223-ht3ry9i0	59	33	larger	large	JJR
cord-104223-ht3ry9i0	59	34	than	than	IN
cord-104223-ht3ry9i0	59	35	the	the	DT
cord-104223-ht3ry9i0	59	36	average	average	JJ
cord-104223-ht3ry9i0	59	37	area	area	NN
cord-104223-ht3ry9i0	59	38	of	of	IN
cord-104223-ht3ry9i0	59	39	unlabeled	unlabeled	JJ
cord-104223-ht3ry9i0	59	40	large	large	JJ
cord-104223-ht3ry9i0	59	41	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	59	42	(	(	-LRB-
cord-104223-ht3ry9i0	59	43	l.2x	l.2x	NN
cord-104223-ht3ry9i0	59	44	)	)	-RRB-
cord-104223-ht3ry9i0	59	45	and	and	CC
cord-104223-ht3ry9i0	59	46	exceeded	exceed	VBD
cord-104223-ht3ry9i0	59	47	the	the	DT
cord-104223-ht3ry9i0	59	48	cutoff	cutoff	NN
cord-104223-ht3ry9i0	59	49	size	size	NN
cord-104223-ht3ry9i0	59	50	by	by	IN
cord-104223-ht3ry9i0	59	51	a	a	DT
cord-104223-ht3ry9i0	59	52	large	large	JJ
cord-104223-ht3ry9i0	59	53	margin	margin	NN
cord-104223-ht3ry9i0	59	54	(	(	-LRB-
cord-104223-ht3ry9i0	59	55	average	average	JJ
cord-104223-ht3ry9i0	59	56	diameter	diameter	NN
cord-104223-ht3ry9i0	59	57	=	=	SYM
cord-104223-ht3ry9i0	59	58	490	490	CD
cord-104223-ht3ry9i0	59	59	am	am	NN
cord-104223-ht3ry9i0	59	60	)	)	-RRB-
cord-104223-ht3ry9i0	59	61	.	.	.
cord-104223-ht3ry9i0	60	1	Immature	immature	JJ
cord-104223-ht3ry9i0	60	2	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	60	3	were	be	VBD
cord-104223-ht3ry9i0	60	4	defined	define	VBN
cord-104223-ht3ry9i0	60	5	by	by	IN
cord-104223-ht3ry9i0	60	6	either	either	DT
cord-104223-ht3ry9i0	60	7	(	(	-LRB-
cord-104223-ht3ry9i0	60	8	a	a	DT
cord-104223-ht3ry9i0	60	9	)	)	-RRB-
cord-104223-ht3ry9i0	60	10	membrane	membrane	NN
cord-104223-ht3ry9i0	60	11	extensions	extension	NNS
cord-104223-ht3ry9i0	60	12	(	(	-LRB-
cord-104223-ht3ry9i0	60	13	bulge	bulge	NN
cord-104223-ht3ry9i0	60	14	or	or	CC
cord-104223-ht3ry9i0	60	15	sac	sac	NN
cord-104223-ht3ry9i0	60	16	;	;	:
cord-104223-ht3ry9i0	60	17	see	see	VB
cord-104223-ht3ry9i0	60	18	Fig	Fig	NNP
cord-104223-ht3ry9i0	60	19	.	.	NNP
cord-104223-ht3ry9i0	60	20	2	2	CD
cord-104223-ht3ry9i0	60	21	)	)	-RRB-
cord-104223-ht3ry9i0	60	22	;	;	:
cord-104223-ht3ry9i0	60	23	(	(	-LRB-
cord-104223-ht3ry9i0	60	24	b	b	NN
cord-104223-ht3ry9i0	60	25	)	)	-RRB-
cord-104223-ht3ry9i0	60	26	irregularities	irregularity	NNS
cord-104223-ht3ry9i0	60	27	in	in	IN
cord-104223-ht3ry9i0	60	28	shape	shape	NN
cord-104223-ht3ry9i0	60	29	;	;	,
cord-104223-ht3ry9i0	60	30	(	(	-LRB-
cord-104223-ht3ry9i0	60	31	c	c	NN
cord-104223-ht3ry9i0	60	32	)	)	-RRB-
cord-104223-ht3ry9i0	60	33	extremely	extremely	RB
cord-104223-ht3ry9i0	60	34	ruffled	ruffled	JJ
cord-104223-ht3ry9i0	60	35	membranes	membrane	NNS
cord-104223-ht3ry9i0	60	36	;	;	:
cord-104223-ht3ry9i0	60	37	or	or	CC
cord-104223-ht3ry9i0	60	38	(	(	-LRB-
cord-104223-ht3ry9i0	60	39	d	d	NN
cord-104223-ht3ry9i0	60	40	)	)	-RRB-
cord-104223-ht3ry9i0	60	41	connection	connection	NN
cord-104223-ht3ry9i0	60	42	to	to	IN
cord-104223-ht3ry9i0	60	43	a	a	DT
cord-104223-ht3ry9i0	60	44	tubule	tubule	NN
cord-104223-ht3ry9i0	60	45	or	or	CC
cord-104223-ht3ry9i0	60	46	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	60	47	stack	stack	NN
cord-104223-ht3ry9i0	60	48	.	.	.
cord-104223-ht3ry9i0	61	1	It	-PRON-	PRP
cord-104223-ht3ry9i0	61	2	is	be	VBZ
cord-104223-ht3ry9i0	61	3	important	important	JJ
cord-104223-ht3ry9i0	61	4	to	to	TO
cord-104223-ht3ry9i0	61	5	note	note	VB
cord-104223-ht3ry9i0	61	6	that	that	IN
cord-104223-ht3ry9i0	61	7	the	the	DT
cord-104223-ht3ry9i0	61	8	percentage	percentage	NN
cord-104223-ht3ry9i0	61	9	of	of	IN
cord-104223-ht3ry9i0	61	10	immature	immature	JJ
cord-104223-ht3ry9i0	61	11	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	61	12	is	be	VBZ
cord-104223-ht3ry9i0	61	13	probably	probably	RB
cord-104223-ht3ry9i0	61	14	an	an	DT
cord-104223-ht3ry9i0	61	15	underestimate	underestimate	NN
cord-104223-ht3ry9i0	61	16	,	,	,
cord-104223-ht3ry9i0	61	17	as	as	IN
cord-104223-ht3ry9i0	61	18	serial	serial	JJ
cord-104223-ht3ry9i0	61	19	sections	section	NNS
cord-104223-ht3ry9i0	61	20	through	through	IN
cord-104223-ht3ry9i0	61	21	bag	bag	NN
cord-104223-ht3ry9i0	61	22	cells	cell	NNS
cord-104223-ht3ry9i0	61	23	often	often	RB
cord-104223-ht3ry9i0	61	24	reveal	reveal	VBP
cord-104223-ht3ry9i0	61	25	sacs	sac	NNS
cord-104223-ht3ry9i0	61	26	on	on	IN
cord-104223-ht3ry9i0	61	27	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	61	28	or	or	CC
cord-104223-ht3ry9i0	61	29	connections	connection	NNS
cord-104223-ht3ry9i0	61	30	to	to	IN
cord-104223-ht3ry9i0	61	31	tubules	tubule	NNS
cord-104223-ht3ry9i0	61	32	that	that	WDT
cord-104223-ht3ry9i0	61	33	are	be	VBP
cord-104223-ht3ry9i0	61	34	absent	absent	JJ
cord-104223-ht3ry9i0	61	35	in	in	IN
cord-104223-ht3ry9i0	61	36	other	other	JJ
cord-104223-ht3ry9i0	61	37	sections	section	NNS
cord-104223-ht3ry9i0	61	38	.	.	.
cord-104223-ht3ry9i0	62	1	For	for	IN
cord-104223-ht3ry9i0	62	2	the	the	DT
cord-104223-ht3ry9i0	62	3	Phe	Phe	NNP
cord-104223-ht3ry9i0	62	4	30-rain	30-rain	CD
cord-104223-ht3ry9i0	62	5	pulse	pulse	NN
cord-104223-ht3ry9i0	62	6	plus	plus	CC
cord-104223-ht3ry9i0	62	7	12	12	CD
cord-104223-ht3ry9i0	62	8	%	%	NN
cord-104223-ht3ry9i0	62	9	chase	chase	NN
cord-104223-ht3ry9i0	62	10	experiment	experiment	NN
cord-104223-ht3ry9i0	62	11	,	,	,
cord-104223-ht3ry9i0	62	12	the	the	DT
cord-104223-ht3ry9i0	62	13	iysosome	iysosome	NNP
cord-104223-ht3ry9i0	62	14	compartment	compartment	NN
cord-104223-ht3ry9i0	62	15	was	be	VBD
cord-104223-ht3ry9i0	62	16	divided	divide	VBN
cord-104223-ht3ry9i0	62	17	into	into	IN
cord-104223-ht3ry9i0	62	18	mottled	mottled	JJ
cord-104223-ht3ry9i0	62	19	DCVs	dcv	NNS
cord-104223-ht3ry9i0	62	20	and	and	CC
cord-104223-ht3ry9i0	62	21	clear	clear	JJ
cord-104223-ht3ry9i0	62	22	lysosomes	lysosome	NNS
cord-104223-ht3ry9i0	62	23	.	.	.
cord-104223-ht3ry9i0	63	1	For	for	IN
cord-104223-ht3ry9i0	63	2	all	all	DT
cord-104223-ht3ry9i0	63	3	experiments	experiment	NNS
cord-104223-ht3ry9i0	63	4	other	other	JJ
cord-104223-ht3ry9i0	63	5	than	than	IN
cord-104223-ht3ry9i0	63	6	Phe	Phe	NNP
cord-104223-ht3ry9i0	63	7	30-rain	30-rain	CD
cord-104223-ht3ry9i0	63	8	pulse	pulse	NN
cord-104223-ht3ry9i0	63	9	plus	plus	CC
cord-104223-ht3ry9i0	63	10	12-h	12-h	CD
cord-104223-ht3ry9i0	63	11	chase	chase	NN
cord-104223-ht3ry9i0	63	12	,	,	,
cord-104223-ht3ry9i0	63	13	the	the	DT
cord-104223-ht3ry9i0	63	14	digitization	digitization	NN
cord-104223-ht3ry9i0	63	15	was	be	VBD
cord-104223-ht3ry9i0	63	16	done	do	VBN
cord-104223-ht3ry9i0	63	17	blindly	blindly	RB
cord-104223-ht3ry9i0	63	18	without	without	IN
cord-104223-ht3ry9i0	63	19	knowledge	knowledge	NN
cord-104223-ht3ry9i0	63	20	of	of	IN
cord-104223-ht3ry9i0	63	21	the	the	DT
cord-104223-ht3ry9i0	63	22	time	time	NN
cord-104223-ht3ry9i0	63	23	point	point	NN
cord-104223-ht3ry9i0	63	24	or	or	CC
cord-104223-ht3ry9i0	63	25	the	the	DT
cord-104223-ht3ry9i0	63	26	label	label	NN
cord-104223-ht3ry9i0	63	27	used	use	VBN
cord-104223-ht3ry9i0	63	28	in	in	IN
cord-104223-ht3ry9i0	63	29	the	the	DT
cord-104223-ht3ry9i0	63	30	experiment	experiment	NN
cord-104223-ht3ry9i0	63	31	.	.	.
cord-104223-ht3ry9i0	64	1	Most	Most	JJS
cord-104223-ht3ry9i0	64	2	time	time	NN
cord-104223-ht3ry9i0	64	3	points	point	NNS
cord-104223-ht3ry9i0	64	4	include	include	VBP
cord-104223-ht3ry9i0	64	5	data	datum	NNS
cord-104223-ht3ry9i0	64	6	from	from	IN
cord-104223-ht3ry9i0	64	7	more	more	JJR
cord-104223-ht3ry9i0	64	8	than	than	IN
cord-104223-ht3ry9i0	64	9	one	one	CD
cord-104223-ht3ry9i0	64	10	application	application	NN
cord-104223-ht3ry9i0	64	11	of	of	IN
cord-104223-ht3ry9i0	64	12	emulsion	emulsion	NN
cord-104223-ht3ry9i0	64	13	.	.	.
cord-104223-ht3ry9i0	65	1	Data	datum	NNS
cord-104223-ht3ry9i0	65	2	was	be	VBD
cord-104223-ht3ry9i0	65	3	pooled	pool	VBN
cord-104223-ht3ry9i0	65	4	from	from	IN
cord-104223-ht3ry9i0	65	5	experiments	experiment	NNS
cord-104223-ht3ry9i0	65	6	as	as	RB
cord-104223-ht3ry9i0	65	7	long	long	RB
cord-104223-ht3ry9i0	65	8	as	as	IN
cord-104223-ht3ry9i0	65	9	the	the	DT
cord-104223-ht3ry9i0	65	10	average	average	JJ
cord-104223-ht3ry9i0	65	11	number	number	NN
cord-104223-ht3ry9i0	65	12	of	of	IN
cord-104223-ht3ry9i0	65	13	grains	grain	NNS
cord-104223-ht3ry9i0	65	14	per	per	IN
cord-104223-ht3ry9i0	65	15	micrograph	micrograph	NN
cord-104223-ht3ry9i0	65	16	was	be	VBD
cord-104223-ht3ry9i0	65	17	within	within	IN
cord-104223-ht3ry9i0	65	18	20	20	CD
cord-104223-ht3ry9i0	65	19	%	%	NN
cord-104223-ht3ry9i0	65	20	.	.	.
cord-104223-ht3ry9i0	66	1	For	for	IN
cord-104223-ht3ry9i0	66	2	the	the	DT
cord-104223-ht3ry9i0	66	3	Phe	Phe	NNP
cord-104223-ht3ry9i0	66	4	5-min	5-min	JJ
cord-104223-ht3ry9i0	66	5	pulse	pulse	NN
cord-104223-ht3ry9i0	66	6	plus	plus	CC
cord-104223-ht3ry9i0	66	7	1-h	1-h	CD
cord-104223-ht3ry9i0	66	8	chase	chase	NN
cord-104223-ht3ry9i0	66	9	experiment	experiment	NN
cord-104223-ht3ry9i0	66	10	,	,	,
cord-104223-ht3ry9i0	66	11	results	result	NNS
cord-104223-ht3ry9i0	66	12	are	be	VBP
cord-104223-ht3ry9i0	66	13	a	a	DT
cord-104223-ht3ry9i0	66	14	weighted	weighted	JJ
cord-104223-ht3ry9i0	66	15	average	average	NN
cord-104223-ht3ry9i0	66	16	of	of	IN
cord-104223-ht3ry9i0	66	17	two	two	CD
cord-104223-ht3ry9i0	66	18	different	different	JJ
cord-104223-ht3ry9i0	66	19	sets	set	NNS
cord-104223-ht3ry9i0	66	20	of	of	IN
cord-104223-ht3ry9i0	66	21	data	datum	NNS
cord-104223-ht3ry9i0	66	22	.	.	.
cord-104223-ht3ry9i0	67	1	The	the	DT
cord-104223-ht3ry9i0	67	2	standard	standard	JJ
cord-104223-ht3ry9i0	67	3	deviations	deviation	NNS
cord-104223-ht3ry9i0	67	4	in	in	IN
cord-104223-ht3ry9i0	67	5	Table	table	NN
cord-104223-ht3ry9i0	67	6	I	-PRON-	PRP
cord-104223-ht3ry9i0	67	7	are	be	VBP
cord-104223-ht3ry9i0	67	8	the	the	DT
cord-104223-ht3ry9i0	67	9	result	result	NN
cord-104223-ht3ry9i0	67	10	of	of	IN
cord-104223-ht3ry9i0	67	11	simulation	simulation	NN
cord-104223-ht3ry9i0	67	12	experiments	experiment	NNS
cord-104223-ht3ry9i0	67	13	(	(	-LRB-
cord-104223-ht3ry9i0	67	14	Miller	Miller	NNP
cord-104223-ht3ry9i0	67	15	et	et	NNP
cord-104223-ht3ry9i0	67	16	al	al	NNP
cord-104223-ht3ry9i0	67	17	.	.	NNP
cord-104223-ht3ry9i0	67	18	,	,	,
cord-104223-ht3ry9i0	67	19	1985	1985	CD
cord-104223-ht3ry9i0	67	20	)	)	-RRB-
cord-104223-ht3ry9i0	67	21	to	to	TO
cord-104223-ht3ry9i0	67	22	evaluate	evaluate	VB
cord-104223-ht3ry9i0	67	23	the	the	DT
cord-104223-ht3ry9i0	67	24	error	error	NN
cord-104223-ht3ry9i0	67	25	inherent	inherent	JJ
cord-104223-ht3ry9i0	67	26	in	in	IN
cord-104223-ht3ry9i0	67	27	the	the	DT
cord-104223-ht3ry9i0	67	28	quantitation	quantitation	NN
cord-104223-ht3ry9i0	67	29	.	.	.
cord-104223-ht3ry9i0	68	1	In	in	IN
cord-104223-ht3ry9i0	68	2	these	these	DT
cord-104223-ht3ry9i0	68	3	experiments	experiment	NNS
cord-104223-ht3ry9i0	68	4	,	,	,
cord-104223-ht3ry9i0	68	5	new	new	JJ
cord-104223-ht3ry9i0	68	6	grains	grain	NNS
cord-104223-ht3ry9i0	68	7	for	for	IN
cord-104223-ht3ry9i0	68	8	each	each	DT
cord-104223-ht3ry9i0	68	9	micrograph	micrograph	NN
cord-104223-ht3ry9i0	68	10	were	be	VBD
cord-104223-ht3ry9i0	68	11	generated	generate	VBN
cord-104223-ht3ry9i0	68	12	using	use	VBG
cord-104223-ht3ry9i0	68	13	the	the	DT
cord-104223-ht3ry9i0	68	14	assumptions	assumption	NNS
cord-104223-ht3ry9i0	68	15	inherent	inherent	JJ
cord-104223-ht3ry9i0	68	16	in	in	IN
cord-104223-ht3ry9i0	68	17	the	the	DT
cord-104223-ht3ry9i0	68	18	algorithm	algorithm	NN
cord-104223-ht3ry9i0	68	19	(	(	-LRB-
cord-104223-ht3ry9i0	68	20	a	a	DT
cord-104223-ht3ry9i0	68	21	poisson	poisson	NN
cord-104223-ht3ry9i0	68	22	distribution	distribution	NN
cord-104223-ht3ry9i0	68	23	of	of	IN
cord-104223-ht3ry9i0	68	24	grains	grain	NNS
cord-104223-ht3ry9i0	68	25	in	in	IN
cord-104223-ht3ry9i0	68	26	a	a	DT
cord-104223-ht3ry9i0	68	27	compartment	compartment	NN
cord-104223-ht3ry9i0	68	28	and	and	CC
cord-104223-ht3ry9i0	68	29	a	a	DT
cord-104223-ht3ry9i0	68	30	gaussian	gaussian	JJ
cord-104223-ht3ry9i0	68	31	error	error	NN
cord-104223-ht3ry9i0	68	32	vector	vector	NN
cord-104223-ht3ry9i0	68	33	between	between	IN
cord-104223-ht3ry9i0	68	34	the	the	DT
cord-104223-ht3ry9i0	68	35	location	location	NN
cord-104223-ht3ry9i0	68	36	of	of	IN
cord-104223-ht3ry9i0	68	37	the	the	DT
cord-104223-ht3ry9i0	68	38	radioactivity	radioactivity	NN
cord-104223-ht3ry9i0	68	39	and	and	CC
cord-104223-ht3ry9i0	68	40	the	the	DT
cord-104223-ht3ry9i0	68	41	center	center	NN
cord-104223-ht3ry9i0	68	42	of	of	IN
cord-104223-ht3ry9i0	68	43	the	the	DT
cord-104223-ht3ry9i0	68	44	simulated	simulated	JJ
cord-104223-ht3ry9i0	68	45	grain	grain	NN
cord-104223-ht3ry9i0	68	46	)	)	-RRB-
cord-104223-ht3ry9i0	68	47	.	.	.
cord-104223-ht3ry9i0	69	1	The	the	DT
cord-104223-ht3ry9i0	69	2	maximum	maximum	JJ
cord-104223-ht3ry9i0	69	3	likelihood	likelihood	NN
cord-104223-ht3ry9i0	69	4	calculation	calculation	NN
cord-104223-ht3ry9i0	69	5	was	be	VBD
cord-104223-ht3ry9i0	69	6	then	then	RB
cord-104223-ht3ry9i0	69	7	repeated	repeat	VBN
cord-104223-ht3ry9i0	69	8	for	for	IN
cord-104223-ht3ry9i0	69	9	the	the	DT
cord-104223-ht3ry9i0	69	10	simulated	simulated	JJ
cord-104223-ht3ry9i0	69	11	grains	grain	NNS
cord-104223-ht3ry9i0	69	12	.	.	.
cord-104223-ht3ry9i0	70	1	Five	five	CD
cord-104223-ht3ry9i0	70	2	simulations	simulation	NNS
cord-104223-ht3ry9i0	70	3	were	be	VBD
cord-104223-ht3ry9i0	70	4	done	do	VBN
cord-104223-ht3ry9i0	70	5	for	for	IN
cord-104223-ht3ry9i0	70	6	each	each	DT
cord-104223-ht3ry9i0	70	7	time	time	NN
cord-104223-ht3ry9i0	70	8	point	point	NN
cord-104223-ht3ry9i0	70	9	,	,	,
cord-104223-ht3ry9i0	70	10	and	and	CC
cord-104223-ht3ry9i0	70	11	the	the	DT
cord-104223-ht3ry9i0	70	12	standard	standard	JJ
cord-104223-ht3ry9i0	70	13	deviation	deviation	NN
cord-104223-ht3ry9i0	70	14	of	of	IN
cord-104223-ht3ry9i0	70	15	these	these	DT
cord-104223-ht3ry9i0	70	16	simulations	simulation	NNS
cord-104223-ht3ry9i0	70	17	is	be	VBZ
cord-104223-ht3ry9i0	70	18	presented	present	VBN
cord-104223-ht3ry9i0	70	19	in	in	IN
cord-104223-ht3ry9i0	70	20	Table	Table	NNP
cord-104223-ht3ry9i0	70	21	I	-PRON-	PRP
cord-104223-ht3ry9i0	70	22	.	.	.
cord-104223-ht3ry9i0	71	1	In	in	IN
cord-104223-ht3ry9i0	71	2	several	several	JJ
cord-104223-ht3ry9i0	71	3	cases	case	NNS
cord-104223-ht3ry9i0	71	4	,	,	,
cord-104223-ht3ry9i0	71	5	the	the	DT
cord-104223-ht3ry9i0	71	6	original	original	JJ
cord-104223-ht3ry9i0	71	7	value	value	NN
cord-104223-ht3ry9i0	71	8	was	be	VBD
cord-104223-ht3ry9i0	71	9	not	not	RB
cord-104223-ht3ry9i0	71	10	within	within	IN
cord-104223-ht3ry9i0	71	11	one	one	CD
cord-104223-ht3ry9i0	71	12	standard	standard	JJ
cord-104223-ht3ry9i0	71	13	deviation	deviation	NN
cord-104223-ht3ry9i0	71	14	of	of	IN
cord-104223-ht3ry9i0	71	15	the	the	DT
cord-104223-ht3ry9i0	71	16	simulation	simulation	NN
cord-104223-ht3ry9i0	71	17	average	average	NN
cord-104223-ht3ry9i0	71	18	,	,	,
cord-104223-ht3ry9i0	71	19	although	although	IN
cord-104223-ht3ry9i0	71	20	all	all	DT
cord-104223-ht3ry9i0	71	21	values	value	NNS
cord-104223-ht3ry9i0	71	22	were	be	VBD
cord-104223-ht3ry9i0	71	23	within	within	IN
cord-104223-ht3ry9i0	71	24	two	two	CD
cord-104223-ht3ry9i0	71	25	standard	standard	JJ
cord-104223-ht3ry9i0	71	26	deviations	deviation	NNS
cord-104223-ht3ry9i0	71	27	.	.	.
cord-104223-ht3ry9i0	72	1	This	this	DT
cord-104223-ht3ry9i0	72	2	occurred	occur	VBD
cord-104223-ht3ry9i0	72	3	mainly	mainly	RB
cord-104223-ht3ry9i0	72	4	in	in	IN
cord-104223-ht3ry9i0	72	5	the	the	DT
cord-104223-ht3ry9i0	72	6	small	small	JJ
cord-104223-ht3ry9i0	72	7	mature	mature	JJ
cord-104223-ht3ry9i0	72	8	and	and	CC
cord-104223-ht3ry9i0	72	9	clear	clear	JJ
cord-104223-ht3ry9i0	72	10	vesicle	vesicle	NN
cord-104223-ht3ry9i0	72	11	compartments	compartment	NNS
cord-104223-ht3ry9i0	72	12	and	and	CC
cord-104223-ht3ry9i0	72	13	is	be	VBZ
cord-104223-ht3ry9i0	72	14	probably	probably	RB
cord-104223-ht3ry9i0	72	15	caused	cause	VBN
cord-104223-ht3ry9i0	72	16	by	by	IN
cord-104223-ht3ry9i0	72	17	the	the	DT
cord-104223-ht3ry9i0	72	18	inhomogeneity	inhomogeneity	NN
cord-104223-ht3ry9i0	72	19	of	of	IN
cord-104223-ht3ry9i0	72	20	these	these	DT
cord-104223-ht3ry9i0	72	21	compartments	compartment	NNS
cord-104223-ht3ry9i0	72	22	.	.	.
cord-104223-ht3ry9i0	73	1	For	for	IN
cord-104223-ht3ry9i0	73	2	example	example	NN
cord-104223-ht3ry9i0	73	3	,	,	,
cord-104223-ht3ry9i0	73	4	the	the	DT
cord-104223-ht3ry9i0	73	5	clear	clear	JJ
cord-104223-ht3ry9i0	73	6	vesicle	vesicle	NN
cord-104223-ht3ry9i0	73	7	compartment	compartment	NN
cord-104223-ht3ry9i0	73	8	contains	contain	VBZ
cord-104223-ht3ry9i0	73	9	transport	transport	NN
cord-104223-ht3ry9i0	73	10	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	73	11	from	from	IN
cord-104223-ht3ry9i0	73	12	ER	ER	NNP
cord-104223-ht3ry9i0	73	13	to	to	IN
cord-104223-ht3ry9i0	73	14	Goigi	Goigi	NNP
cord-104223-ht3ry9i0	73	15	apparatus	apparatus	NN
cord-104223-ht3ry9i0	73	16	,	,	,
cord-104223-ht3ry9i0	73	17	from	from	IN
cord-104223-ht3ry9i0	73	18	one	one	CD
cord-104223-ht3ry9i0	73	19	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	73	20	slack	slack	NN
cord-104223-ht3ry9i0	73	21	to	to	IN
cord-104223-ht3ry9i0	73	22	another	another	DT
cord-104223-ht3ry9i0	73	23	,	,	,
cord-104223-ht3ry9i0	73	24	and	and	CC
cord-104223-ht3ry9i0	73	25	from	from	IN
cord-104223-ht3ry9i0	73	26	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	73	27	apparatus	apparatus	NN
cord-104223-ht3ry9i0	73	28	to	to	IN
cord-104223-ht3ry9i0	73	29	plasma	plasma	NN
cord-104223-ht3ry9i0	73	30	membrane	membrane	NN
cord-104223-ht3ry9i0	73	31	as	as	RB
cord-104223-ht3ry9i0	73	32	well	well	RB
cord-104223-ht3ry9i0	73	33	as	as	IN
cord-104223-ht3ry9i0	73	34	parts	part	NNS
cord-104223-ht3ry9i0	73	35	of	of	IN
cord-104223-ht3ry9i0	73	36	the	the	DT
cord-104223-ht3ry9i0	73	37	TGN	TGN	NNP
cord-104223-ht3ry9i0	73	38	,	,	,
cord-104223-ht3ry9i0	73	39	primary	primary	JJ
cord-104223-ht3ry9i0	73	40	lysosomes	lysosome	NNS
cord-104223-ht3ry9i0	73	41	,	,	,
cord-104223-ht3ry9i0	73	42	and	and	CC
cord-104223-ht3ry9i0	73	43	other	other	JJ
cord-104223-ht3ry9i0	73	44	compartments	compartment	NNS
cord-104223-ht3ry9i0	73	45	that	that	WDT
cord-104223-ht3ry9i0	73	46	can	can	MD
cord-104223-ht3ry9i0	73	47	not	not	RB
cord-104223-ht3ry9i0	73	48	be	be	VB
cord-104223-ht3ry9i0	73	49	differentiated	differentiate	VBN
cord-104223-ht3ry9i0	73	50	by	by	IN
cord-104223-ht3ry9i0	73	51	morphology	morphology	NN
cord-104223-ht3ry9i0	73	52	.	.	.
cord-104223-ht3ry9i0	74	1	The	the	DT
cord-104223-ht3ry9i0	74	2	simulation	simulation	NN
cord-104223-ht3ry9i0	74	3	treats	treat	VBZ
cord-104223-ht3ry9i0	74	4	these	these	DT
cord-104223-ht3ry9i0	74	5	as	as	IN
cord-104223-ht3ry9i0	74	6	homogeneous	homogeneous	JJ
cord-104223-ht3ry9i0	74	7	compartments	compartment	NNS
cord-104223-ht3ry9i0	74	8	,	,	,
cord-104223-ht3ry9i0	74	9	while	while	IN
cord-104223-ht3ry9i0	74	10	the	the	DT
cord-104223-ht3ry9i0	74	11	grains	grain	NNS
cord-104223-ht3ry9i0	74	12	may	may	MD
cord-104223-ht3ry9i0	74	13	have	have	VB
cord-104223-ht3ry9i0	74	14	been	be	VBN
cord-104223-ht3ry9i0	74	15	coming	come	VBG
cord-104223-ht3ry9i0	74	16	from	from	IN
cord-104223-ht3ry9i0	74	17	a	a	DT
cord-104223-ht3ry9i0	74	18	small	small	JJ
cord-104223-ht3ry9i0	74	19	subset	subset	NN
cord-104223-ht3ry9i0	74	20	of	of	IN
cord-104223-ht3ry9i0	74	21	these	these	DT
cord-104223-ht3ry9i0	74	22	compartments	compartment	NNS
cord-104223-ht3ry9i0	74	23	.	.	.
cord-104223-ht3ry9i0	75	1	Therefore	therefore	RB
cord-104223-ht3ry9i0	75	2	,	,	,
cord-104223-ht3ry9i0	75	3	the	the	DT
cord-104223-ht3ry9i0	75	4	simulations	simulation	NNS
cord-104223-ht3ry9i0	75	5	arrive	arrive	VBP
cord-104223-ht3ry9i0	75	6	at	at	IN
cord-104223-ht3ry9i0	75	7	estimates	estimate	NNS
cord-104223-ht3ry9i0	75	8	different	different	JJ
cord-104223-ht3ry9i0	75	9	from	from	IN
cord-104223-ht3ry9i0	75	10	the	the	DT
cord-104223-ht3ry9i0	75	11	original	original	JJ
cord-104223-ht3ry9i0	75	12	computation	computation	NN
cord-104223-ht3ry9i0	75	13	.	.	.
cord-104223-ht3ry9i0	76	1	The	the	DT
cord-104223-ht3ry9i0	76	2	small	small	JJ
cord-104223-ht3ry9i0	76	3	mature	mature	JJ
cord-104223-ht3ry9i0	76	4	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	76	5	at	at	IN
cord-104223-ht3ry9i0	76	6	early	early	JJ
cord-104223-ht3ry9i0	76	7	time	time	NN
cord-104223-ht3ry9i0	76	8	points	point	NNS
cord-104223-ht3ry9i0	76	9	are	be	VBP
cord-104223-ht3ry9i0	76	10	usually	usually	RB
cord-104223-ht3ry9i0	76	11	found	find	VBN
cord-104223-ht3ry9i0	76	12	close	close	RB
cord-104223-ht3ry9i0	76	13	to	to	IN
cord-104223-ht3ry9i0	76	14	the	the	DT
cord-104223-ht3ry9i0	76	15	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	76	16	apparatus	apparatus	NN
cord-104223-ht3ry9i0	76	17	and	and	CC
cord-104223-ht3ry9i0	76	18	thus	thus	RB
cord-104223-ht3ry9i0	76	19	do	do	VBP
cord-104223-ht3ry9i0	76	20	not	not	RB
cord-104223-ht3ry9i0	76	21	share	share	VB
cord-104223-ht3ry9i0	76	22	the	the	DT
cord-104223-ht3ry9i0	76	23	distribution	distribution	NN
cord-104223-ht3ry9i0	76	24	of	of	IN
cord-104223-ht3ry9i0	76	25	the	the	DT
cord-104223-ht3ry9i0	76	26	majority	majority	NN
cord-104223-ht3ry9i0	76	27	of	of	IN
cord-104223-ht3ry9i0	76	28	small	small	JJ
cord-104223-ht3ry9i0	76	29	mature	mature	JJ
cord-104223-ht3ry9i0	76	30	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	76	31	,	,	,
cord-104223-ht3ry9i0	76	32	again	again	RB
cord-104223-ht3ry9i0	76	33	causing	cause	VBG
cord-104223-ht3ry9i0	76	34	differences	difference	NNS
cord-104223-ht3ry9i0	76	35	between	between	IN
cord-104223-ht3ry9i0	76	36	the	the	DT
cord-104223-ht3ry9i0	76	37	simulation	simulation	NN
cord-104223-ht3ry9i0	76	38	and	and	CC
cord-104223-ht3ry9i0	76	39	the	the	DT
cord-104223-ht3ry9i0	76	40	original	original	JJ
cord-104223-ht3ry9i0	76	41	experiment	experiment	NN
cord-104223-ht3ry9i0	76	42	.	.	.
cord-104223-ht3ry9i0	77	1	Other	other	JJ
cord-104223-ht3ry9i0	77	2	errors	error	NNS
cord-104223-ht3ry9i0	77	3	,	,	,
cord-104223-ht3ry9i0	77	4	such	such	JJ
cord-104223-ht3ry9i0	77	5	as	as	IN
cord-104223-ht3ry9i0	77	6	sampling	sampling	NN
cord-104223-ht3ry9i0	77	7	bias	bias	NN
cord-104223-ht3ry9i0	77	8	and	and	CC
cord-104223-ht3ry9i0	77	9	digitation	digitation	NN
cord-104223-ht3ry9i0	77	10	errors	error	NNS
cord-104223-ht3ry9i0	77	11	,	,	,
cord-104223-ht3ry9i0	77	12	are	be	VBP
cord-104223-ht3ry9i0	77	13	not	not	RB
cord-104223-ht3ry9i0	77	14	included	include	VBN
cord-104223-ht3ry9i0	77	15	in	in	IN
cord-104223-ht3ry9i0	77	16	the	the	DT
cord-104223-ht3ry9i0	77	17	standard	standard	JJ
cord-104223-ht3ry9i0	77	18	deviations	deviation	NNS
cord-104223-ht3ry9i0	77	19	and	and	CC
cord-104223-ht3ry9i0	77	20	probably	probably	RB
cord-104223-ht3ry9i0	77	21	add	add	VB
cord-104223-ht3ry9i0	77	22	to	to	IN
cord-104223-ht3ry9i0	77	23	the	the	DT
cord-104223-ht3ry9i0	77	24	total	total	JJ
cord-104223-ht3ry9i0	77	25	error	error	NN
cord-104223-ht3ry9i0	77	26	in	in	IN
cord-104223-ht3ry9i0	77	27	the	the	DT
cord-104223-ht3ry9i0	77	28	experiment	experiment	NN
cord-104223-ht3ry9i0	77	29	.	.	.
cord-104223-ht3ry9i0	78	1	It	-PRON-	PRP
cord-104223-ht3ry9i0	78	2	is	be	VBZ
cord-104223-ht3ry9i0	78	3	difficult	difficult	JJ
cord-104223-ht3ry9i0	78	4	to	to	TO
cord-104223-ht3ry9i0	78	5	quantitate	quantitate	VB
cord-104223-ht3ry9i0	78	6	these	these	DT
cord-104223-ht3ry9i0	78	7	errors	error	NNS
cord-104223-ht3ry9i0	78	8	and	and	CC
cord-104223-ht3ry9i0	78	9	they	-PRON-	PRP
cord-104223-ht3ry9i0	78	10	are	be	VBP
cord-104223-ht3ry9i0	78	11	presumed	presume	VBN
cord-104223-ht3ry9i0	78	12	to	to	TO
cord-104223-ht3ry9i0	78	13	be	be	VB
cord-104223-ht3ry9i0	78	14	minor	minor	JJ
cord-104223-ht3ry9i0	78	15	contributions	contribution	NNS
cord-104223-ht3ry9i0	78	16	compared	compare	VBN
cord-104223-ht3ry9i0	78	17	with	with	IN
cord-104223-ht3ry9i0	78	18	the	the	DT
cord-104223-ht3ry9i0	78	19	errors	error	NNS
cord-104223-ht3ry9i0	78	20	due	due	JJ
cord-104223-ht3ry9i0	78	21	to	to	IN
cord-104223-ht3ry9i0	78	22	the	the	DT
cord-104223-ht3ry9i0	78	23	quantitation	quantitation	NN
cord-104223-ht3ry9i0	78	24	procedure	procedure	NN
cord-104223-ht3ry9i0	78	25	.	.	.
cord-104223-ht3ry9i0	79	1	Simulations	simulation	NNS
cord-104223-ht3ry9i0	79	2	were	be	VBD
cord-104223-ht3ry9i0	79	3	also	also	RB
cord-104223-ht3ry9i0	79	4	used	use	VBN
cord-104223-ht3ry9i0	79	5	to	to	TO
cord-104223-ht3ry9i0	79	6	evaluate	evaluate	VB
cord-104223-ht3ry9i0	79	7	the	the	DT
cord-104223-ht3ry9i0	79	8	possibility	possibility	NN
cord-104223-ht3ry9i0	79	9	that	that	IN
cord-104223-ht3ry9i0	79	10	the	the	DT
cord-104223-ht3ry9i0	79	11	high	high	JJ
cord-104223-ht3ry9i0	79	12	percenlage	percenlage	NN
cord-104223-ht3ry9i0	79	13	of	of	IN
cord-104223-ht3ry9i0	79	14	grains	grain	NNS
cord-104223-ht3ry9i0	79	15	in	in	IN
cord-104223-ht3ry9i0	79	16	clear	clear	JJ
cord-104223-ht3ry9i0	79	17	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	79	18	resulted	result	VBD
cord-104223-ht3ry9i0	79	19	from	from	IN
cord-104223-ht3ry9i0	79	20	their	-PRON-	PRP$
cord-104223-ht3ry9i0	79	21	proximity	proximity	NN
cord-104223-ht3ry9i0	79	22	to	to	IN
cord-104223-ht3ry9i0	79	23	both	both	CC
cord-104223-ht3ry9i0	79	24	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	79	25	apparatus	apparatus	NN
cord-104223-ht3ry9i0	79	26	and	and	CC
cord-104223-ht3ry9i0	79	27	small	small	JJ
cord-104223-ht3ry9i0	79	28	immature	immature	JJ
cord-104223-ht3ry9i0	79	29	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	79	30	.	.	.
cord-104223-ht3ry9i0	80	1	At	at	IN
cord-104223-ht3ry9i0	80	2	three	three	CD
cord-104223-ht3ry9i0	80	3	time	time	NN
cord-104223-ht3ry9i0	80	4	points	point	NNS
cord-104223-ht3ry9i0	80	5	(	(	-LRB-
cord-104223-ht3ry9i0	80	6	Phe	Phe	NNP
cord-104223-ht3ry9i0	80	7	30rain	30rain	CD
cord-104223-ht3ry9i0	80	8	pulse	pulse	NN
cord-104223-ht3ry9i0	80	9	plus	plus	CC
cord-104223-ht3ry9i0	80	10	30-min	30-min	CD
cord-104223-ht3ry9i0	80	11	chase	chase	NN
cord-104223-ht3ry9i0	80	12	,	,	,
cord-104223-ht3ry9i0	80	13	Ile	Ile	NNP
cord-104223-ht3ry9i0	80	14	30-min	30-min	CD
cord-104223-ht3ry9i0	80	15	pulse	pulse	NN
cord-104223-ht3ry9i0	80	16	plus	plus	CC
cord-104223-ht3ry9i0	81	1	30-rain	30-rain	CD
cord-104223-ht3ry9i0	81	2	chase	chase	NNP
cord-104223-ht3ry9i0	81	3	,	,	,
cord-104223-ht3ry9i0	81	4	and	and	CC
cord-104223-ht3ry9i0	81	5	Phe	Phe	NNP
cord-104223-ht3ry9i0	81	6	5-rain	5-rain	CD
cord-104223-ht3ry9i0	81	7	pulse	pulse	NN
cord-104223-ht3ry9i0	81	8	plus	plus	IN
cord-104223-ht3ry9i0	81	9	30-rain	30-rain	CD
cord-104223-ht3ry9i0	81	10	chase	chase	NNP
cord-104223-ht3ry9i0	81	11	)	)	-RRB-
cord-104223-ht3ry9i0	81	12	,	,	,
cord-104223-ht3ry9i0	81	13	the	the	DT
cord-104223-ht3ry9i0	81	14	counts	count	NNS
cord-104223-ht3ry9i0	81	15	in	in	IN
cord-104223-ht3ry9i0	81	16	clear	clear	JJ
cord-104223-ht3ry9i0	81	17	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	81	18	were	be	VBD
cord-104223-ht3ry9i0	81	19	assigned	assign	VBN
cord-104223-ht3ry9i0	81	20	proportionally	proportionally	RB
cord-104223-ht3ry9i0	81	21	to	to	IN
cord-104223-ht3ry9i0	81	22	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	81	23	apparatus	apparatus	NN
cord-104223-ht3ry9i0	81	24	and	and	CC
cord-104223-ht3ry9i0	81	25	small	small	JJ
cord-104223-ht3ry9i0	81	26	immature	immature	JJ
cord-104223-ht3ry9i0	81	27	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	81	28	,	,	,
cord-104223-ht3ry9i0	81	29	and	and	CC
cord-104223-ht3ry9i0	81	30	a	a	DT
cord-104223-ht3ry9i0	81	31	total	total	NN
cord-104223-ht3ry9i0	81	32	of	of	IN
cord-104223-ht3ry9i0	81	33	10	10	CD
cord-104223-ht3ry9i0	81	34	simulations	simulation	NNS
cord-104223-ht3ry9i0	81	35	were	be	VBD
cord-104223-ht3ry9i0	81	36	carried	carry	VBN
cord-104223-ht3ry9i0	81	37	out	out	RP
cord-104223-ht3ry9i0	81	38	with	with	IN
cord-104223-ht3ry9i0	81	39	these	these	DT
cord-104223-ht3ry9i0	81	40	new	new	JJ
cord-104223-ht3ry9i0	81	41	densities	density	NNS
cord-104223-ht3ry9i0	81	42	.	.	.
cord-104223-ht3ry9i0	82	1	In	in	IN
cord-104223-ht3ry9i0	82	2	these	these	DT
cord-104223-ht3ry9i0	82	3	10	10	CD
cord-104223-ht3ry9i0	82	4	simulations	simulation	NNS
cord-104223-ht3ry9i0	82	5	,	,	,
cord-104223-ht3ry9i0	82	6	the	the	DT
cord-104223-ht3ry9i0	82	7	maximum	maximum	JJ
cord-104223-ht3ry9i0	82	8	value	value	NN
cord-104223-ht3ry9i0	82	9	of	of	IN
cord-104223-ht3ry9i0	82	10	counts	count	NNS
cord-104223-ht3ry9i0	82	11	ever	ever	RB
cord-104223-ht3ry9i0	82	12	seen	see	VBN
cord-104223-ht3ry9i0	82	13	over	over	IN
cord-104223-ht3ry9i0	82	14	clear	clear	JJ
cord-104223-ht3ry9i0	82	15	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	82	16	is	be	VBZ
cord-104223-ht3ry9i0	82	17	3	3	CD
cord-104223-ht3ry9i0	82	18	%	%	NN
cord-104223-ht3ry9i0	82	19	,	,	,
cord-104223-ht3ry9i0	82	20	and	and	CC
cord-104223-ht3ry9i0	82	21	thus	thus	RB
cord-104223-ht3ry9i0	82	22	we	-PRON-	PRP
cord-104223-ht3ry9i0	82	23	conclude	conclude	VBP
cord-104223-ht3ry9i0	82	24	that	that	IN
cord-104223-ht3ry9i0	82	25	the	the	DT
cord-104223-ht3ry9i0	82	26	high	high	JJ
cord-104223-ht3ry9i0	82	27	values	value	NNS
cord-104223-ht3ry9i0	82	28	seen	see	VBN
cord-104223-ht3ry9i0	82	29	over	over	IN
cord-104223-ht3ry9i0	82	30	this	this	DT
cord-104223-ht3ry9i0	82	31	compartment	compartment	NN
cord-104223-ht3ry9i0	82	32	at	at	IN
cord-104223-ht3ry9i0	82	33	these	these	DT
cord-104223-ht3ry9i0	82	34	time	time	NN
cord-104223-ht3ry9i0	82	35	points	point	NNS
cord-104223-ht3ry9i0	82	36	is	be	VBZ
cord-104223-ht3ry9i0	82	37	not	not	RB
cord-104223-ht3ry9i0	82	38	due	due	JJ
cord-104223-ht3ry9i0	82	39	to	to	IN
cord-104223-ht3ry9i0	82	40	their	-PRON-	PRP$
cord-104223-ht3ry9i0	82	41	proximity	proximity	NN
cord-104223-ht3ry9i0	82	42	to	to	IN
cord-104223-ht3ry9i0	82	43	other	other	JJ
cord-104223-ht3ry9i0	82	44	compartments	compartment	NNS
cord-104223-ht3ry9i0	82	45	that	that	WDT
cord-104223-ht3ry9i0	82	46	contain	contain	VBP
cord-104223-ht3ry9i0	82	47	radioactivity	radioactivity	NN
cord-104223-ht3ry9i0	82	48	.	.	.
cord-104223-ht3ry9i0	83	1	One	one	CD
cord-104223-ht3ry9i0	83	2	source	source	NN
cord-104223-ht3ry9i0	83	3	of	of	IN
cord-104223-ht3ry9i0	83	4	concern	concern	NN
cord-104223-ht3ry9i0	83	5	is	be	VBZ
cord-104223-ht3ry9i0	83	6	the	the	DT
cord-104223-ht3ry9i0	83	7	relative	relative	JJ
cord-104223-ht3ry9i0	83	8	incorporation	incorporation	NN
cord-104223-ht3ry9i0	83	9	and	and	CC
cord-104223-ht3ry9i0	83	10	washout	washout	NN
cord-104223-ht3ry9i0	83	11	of	of	IN
cord-104223-ht3ry9i0	83	12	[	[	-LRB-
cord-104223-ht3ry9i0	83	13	3H]Ile	3h]ile	CD
cord-104223-ht3ry9i0	83	14	and	and	CC
cord-104223-ht3ry9i0	83	15	[	[	-LRB-
cord-104223-ht3ry9i0	83	16	3H]Phe	3h]phe	CD
cord-104223-ht3ry9i0	83	17	.	.	.
cord-104223-ht3ry9i0	84	1	As	as	IN
cord-104223-ht3ry9i0	84	2	our	-PRON-	PRP$
cord-104223-ht3ry9i0	84	3	results	result	NNS
cord-104223-ht3ry9i0	84	4	are	be	VBP
cord-104223-ht3ry9i0	84	5	mainly	mainly	RB
cord-104223-ht3ry9i0	84	6	based	base	VBN
cord-104223-ht3ry9i0	84	7	on	on	IN
cord-104223-ht3ry9i0	84	8	comparing	compare	VBG
cord-104223-ht3ry9i0	84	9	the	the	DT
cord-104223-ht3ry9i0	84	10	flow	flow	NN
cord-104223-ht3ry9i0	84	11	of	of	IN
cord-104223-ht3ry9i0	84	12	the	the	DT
cord-104223-ht3ry9i0	84	13	different	different	JJ
cord-104223-ht3ry9i0	84	14	regions	region	NNS
cord-104223-ht3ry9i0	84	15	of	of	IN
cord-104223-ht3ry9i0	84	16	the	the	DT
cord-104223-ht3ry9i0	84	17	prohormone	prohormone	NN
cord-104223-ht3ry9i0	84	18	,	,	,
cord-104223-ht3ry9i0	84	19	as	as	IN
cord-104223-ht3ry9i0	84	20	opposed	oppose	VBN
cord-104223-ht3ry9i0	84	21	to	to	IN
cord-104223-ht3ry9i0	84	22	comparing	compare	VBG
cord-104223-ht3ry9i0	84	23	the	the	DT
cord-104223-ht3ry9i0	84	24	absolute	absolute	JJ
cord-104223-ht3ry9i0	84	25	position	position	NN
cord-104223-ht3ry9i0	84	26	at	at	IN
cord-104223-ht3ry9i0	84	27	a	a	DT
cord-104223-ht3ry9i0	84	28	time	time	NN
cord-104223-ht3ry9i0	84	29	point	point	NN
cord-104223-ht3ry9i0	84	30	,	,	,
cord-104223-ht3ry9i0	84	31	we	-PRON-	PRP
cord-104223-ht3ry9i0	84	32	do	do	VBP
cord-104223-ht3ry9i0	84	33	not	not	RB
cord-104223-ht3ry9i0	84	34	feel	feel	VB
cord-104223-ht3ry9i0	84	35	that	that	IN
cord-104223-ht3ry9i0	84	36	possible	possible	JJ
cord-104223-ht3ry9i0	84	37	differences	difference	NNS
cord-104223-ht3ry9i0	84	38	in	in	IN
cord-104223-ht3ry9i0	84	39	incorporation	incorporation	NN
cord-104223-ht3ry9i0	84	40	and	and	CC
cord-104223-ht3ry9i0	84	41	washout	washout	NN
cord-104223-ht3ry9i0	84	42	would	would	MD
cord-104223-ht3ry9i0	84	43	affect	affect	VB
cord-104223-ht3ry9i0	84	44	our	-PRON-	PRP$
cord-104223-ht3ry9i0	84	45	results	result	NNS
cord-104223-ht3ry9i0	84	46	.	.	.
cord-104223-ht3ry9i0	85	1	The	the	DT
cord-104223-ht3ry9i0	85	2	relatively	relatively	RB
cord-104223-ht3ry9i0	85	3	slow	slow	JJ
cord-104223-ht3ry9i0	85	4	washout	washout	NN
cord-104223-ht3ry9i0	85	5	of	of	IN
cord-104223-ht3ry9i0	85	6	accumulated	accumulate	VBN
cord-104223-ht3ry9i0	85	7	[	[	-LRB-
cord-104223-ht3ry9i0	85	8	3H]Phe	3h]phe	CD
cord-104223-ht3ry9i0	85	9	probably	probably	RB
cord-104223-ht3ry9i0	85	10	accounts	account	VBZ
cord-104223-ht3ry9i0	85	11	for	for	IN
cord-104223-ht3ry9i0	85	12	the	the	DT
cord-104223-ht3ry9i0	85	13	difference	difference	NN
cord-104223-ht3ry9i0	85	14	in	in	IN
cord-104223-ht3ry9i0	85	15	absolute	absolute	JJ
cord-104223-ht3ry9i0	85	16	timing	timing	NN
cord-104223-ht3ry9i0	85	17	observed	observe	VBD
cord-104223-ht3ry9i0	85	18	between	between	IN
cord-104223-ht3ry9i0	85	19	the	the	DT
cord-104223-ht3ry9i0	85	20	experiments	experiment	NNS
cord-104223-ht3ry9i0	85	21	with	with	IN
cord-104223-ht3ry9i0	85	22	5-and	5-and	CD
cord-104223-ht3ry9i0	85	23	30-rain	30-rain	CD
cord-104223-ht3ry9i0	85	24	pulses	pulse	NNS
cord-104223-ht3ry9i0	85	25	of	of	IN
cord-104223-ht3ry9i0	85	26	[	[	-LRB-
cord-104223-ht3ry9i0	85	27	3H]Phe	3h]phe	CD
cord-104223-ht3ry9i0	85	28	.	.	.
cord-104223-ht3ry9i0	86	1	Bag	bag	NN
cord-104223-ht3ry9i0	86	2	cell	cell	NN
cord-104223-ht3ry9i0	86	3	clusters	cluster	NNS
cord-104223-ht3ry9i0	86	4	were	be	VBD
cord-104223-ht3ry9i0	86	5	isolated	isolate	VBN
cord-104223-ht3ry9i0	86	6	and	and	CC
cord-104223-ht3ry9i0	86	7	fixed	fix	VBN
cord-104223-ht3ry9i0	86	8	in	in	IN
cord-104223-ht3ry9i0	86	9	1	1	CD
cord-104223-ht3ry9i0	86	10	%	%	NN
cord-104223-ht3ry9i0	86	11	glutaraldehyde	glutaraldehyde	NN
cord-104223-ht3ry9i0	86	12	,	,	,
cord-104223-ht3ry9i0	86	13	2	2	CD
cord-104223-ht3ry9i0	86	14	%	%	NN
cord-104223-ht3ry9i0	86	15	paraformaldehyde	paraformaldehyde	NNP
cord-104223-ht3ry9i0	86	16	,	,	,
cord-104223-ht3ry9i0	86	17	1	1	CD
cord-104223-ht3ry9i0	86	18	%	%	NN
cord-104223-ht3ry9i0	86	19	DMSO	DMSO	NNP
cord-104223-ht3ry9i0	86	20	,	,	,
cord-104223-ht3ry9i0	86	21	0.3	0.3	CD
cord-104223-ht3ry9i0	86	22	M	m	NN
cord-104223-ht3ry9i0	86	23	sucrose	sucrose	NN
cord-104223-ht3ry9i0	86	24	in	in	IN
cord-104223-ht3ry9i0	86	25	0.1	0.1	CD
cord-104223-ht3ry9i0	86	26	M	M	NNP
cord-104223-ht3ry9i0	86	27	Na	Na	NNP
cord-104223-ht3ry9i0	86	28	cacodylate	cacodylate	NN
cord-104223-ht3ry9i0	86	29	buffer	buffer	NN
cord-104223-ht3ry9i0	86	30	,	,	,
cord-104223-ht3ry9i0	86	31	pH	pH	NNP
cord-104223-ht3ry9i0	86	32	7.4	7.4	CD
cord-104223-ht3ry9i0	86	33	,	,	,
cord-104223-ht3ry9i0	86	34	for	for	IN
cord-104223-ht3ry9i0	86	35	90	90	CD
cord-104223-ht3ry9i0	86	36	min	min	NN
cord-104223-ht3ry9i0	86	37	at	at	IN
cord-104223-ht3ry9i0	86	38	4	4	CD
cord-104223-ht3ry9i0	86	39	°	°	NN
cord-104223-ht3ry9i0	86	40	C	c	NN
cord-104223-ht3ry9i0	86	41	.	.	.
cord-104223-ht3ry9i0	87	1	The	the	DT
cord-104223-ht3ry9i0	87	2	sheath	sheath	NN
cord-104223-ht3ry9i0	87	3	was	be	VBD
cord-104223-ht3ry9i0	87	4	then	then	RB
cord-104223-ht3ry9i0	87	5	dissected	dissect	VBN
cord-104223-ht3ry9i0	87	6	from	from	IN
cord-104223-ht3ry9i0	87	7	the	the	DT
cord-104223-ht3ry9i0	87	8	cluster	cluster	NN
cord-104223-ht3ry9i0	87	9	,	,	,
cord-104223-ht3ry9i0	87	10	and	and	CC
cord-104223-ht3ry9i0	87	11	the	the	DT
cord-104223-ht3ry9i0	87	12	cluster	cluster	NN
cord-104223-ht3ry9i0	87	13	was	be	VBD
cord-104223-ht3ry9i0	87	14	washed	wash	VBN
cord-104223-ht3ry9i0	87	15	in	in	IN
cord-104223-ht3ry9i0	87	16	0.05	0.05	CD
cord-104223-ht3ry9i0	87	17	M	M	NNP
cord-104223-ht3ry9i0	87	18	Na	Na	NNP
cord-104223-ht3ry9i0	87	19	Acetate	Acetate	NNP
cord-104223-ht3ry9i0	87	20	,	,	,
cord-104223-ht3ry9i0	87	21	pH	pH	NNP
cord-104223-ht3ry9i0	87	22	5	5	CD
cord-104223-ht3ry9i0	87	23	,	,	,
cord-104223-ht3ry9i0	87	24	and	and	CC
cord-104223-ht3ry9i0	87	25	incubated	incubate	VBN
cord-104223-ht3ry9i0	87	26	in	in	IN
cord-104223-ht3ry9i0	87	27	0.1	0.1	CD
cord-104223-ht3ry9i0	87	28	%	%	NN
cord-104223-ht3ry9i0	87	29	cytidine	cytidine	NN
cord-104223-ht3ry9i0	87	30	monophosphate	monophosphate	NN
cord-104223-ht3ry9i0	88	1	(	(	-LRB-
cord-104223-ht3ry9i0	88	2	Sigma	Sigma	NNP
cord-104223-ht3ry9i0	88	3	Chemical	Chemical	NNP
cord-104223-ht3ry9i0	88	4	Co.	Co.	NNP
cord-104223-ht3ry9i0	88	5	,	,	,
cord-104223-ht3ry9i0	88	6	St.	St.	NNP
cord-104223-ht3ry9i0	88	7	Louis	Louis	NNP
cord-104223-ht3ry9i0	88	8	,	,	,
cord-104223-ht3ry9i0	88	9	MO	MO	NNP
cord-104223-ht3ry9i0	88	10	)	)	-RRB-
cord-104223-ht3ry9i0	88	11	or	or	CC
cord-104223-ht3ry9i0	88	12	glycerophosphate	glycerophosphate	NNP
cord-104223-ht3ry9i0	88	13	(	(	-LRB-
cord-104223-ht3ry9i0	88	14	Sigma	Sigma	NNP
cord-104223-ht3ry9i0	88	15	Chemical	Chemical	NNP
cord-104223-ht3ry9i0	88	16	Co.	Co.	NNP
cord-104223-ht3ry9i0	88	17	)	)	-RRB-
cord-104223-ht3ry9i0	88	18	and	and	CC
cord-104223-ht3ry9i0	88	19	0.15	0.15	CD
cord-104223-ht3ry9i0	88	20	%	%	NN
cord-104223-ht3ry9i0	88	21	lead	lead	NN
cord-104223-ht3ry9i0	88	22	nitrate	nitrate	NN
cord-104223-ht3ry9i0	88	23	in	in	IN
cord-104223-ht3ry9i0	88	24	0.05	0.05	CD
cord-104223-ht3ry9i0	88	25	M	M	NNP
cord-104223-ht3ry9i0	88	26	Na	Na	NNP
cord-104223-ht3ry9i0	88	27	acelate	acelate	NNP
cord-104223-ht3ry9i0	88	28	,	,	,
cord-104223-ht3ry9i0	88	29	pH	pH	NNP
cord-104223-ht3ry9i0	88	30	5	5	CD
cord-104223-ht3ry9i0	88	31	,	,	,
cord-104223-ht3ry9i0	88	32	for	for	IN
cord-104223-ht3ry9i0	88	33	90	90	CD
cord-104223-ht3ry9i0	88	34	rain	rain	NN
cord-104223-ht3ry9i0	88	35	at	at	IN
cord-104223-ht3ry9i0	88	36	37	37	CD
cord-104223-ht3ry9i0	88	37	°	°	NN
cord-104223-ht3ry9i0	88	38	C	c	NN
cord-104223-ht3ry9i0	88	39	(	(	-LRB-
cord-104223-ht3ry9i0	88	40	Novikoff	Novikoff	NNP
cord-104223-ht3ry9i0	88	41	et	et	NNP
cord-104223-ht3ry9i0	88	42	al	al	NNP
cord-104223-ht3ry9i0	88	43	.	.	NNP
cord-104223-ht3ry9i0	88	44	,	,	,
cord-104223-ht3ry9i0	88	45	1971	1971	CD
cord-104223-ht3ry9i0	88	46	)	)	-RRB-
cord-104223-ht3ry9i0	88	47	.	.	.
cord-104223-ht3ry9i0	89	1	Results	result	NNS
cord-104223-ht3ry9i0	89	2	were	be	VBD
cord-104223-ht3ry9i0	89	3	similar	similar	JJ
cord-104223-ht3ry9i0	89	4	for	for	IN
cord-104223-ht3ry9i0	89	5	both	both	DT
cord-104223-ht3ry9i0	89	6	of	of	IN
cord-104223-ht3ry9i0	89	7	the	the	DT
cord-104223-ht3ry9i0	89	8	labels	label	NNS
cord-104223-ht3ry9i0	89	9	,	,	,
cord-104223-ht3ry9i0	89	10	and	and	CC
cord-104223-ht3ry9i0	89	11	control	control	NN
cord-104223-ht3ry9i0	89	12	preparations	preparation	NNS
cord-104223-ht3ry9i0	89	13	without	without	IN
cord-104223-ht3ry9i0	89	14	substrate	substrate	NN
cord-104223-ht3ry9i0	89	15	showed	show	VBD
cord-104223-ht3ry9i0	89	16	no	no	DT
cord-104223-ht3ry9i0	89	17	lead	lead	NN
cord-104223-ht3ry9i0	89	18	precipitate	precipitate	NN
cord-104223-ht3ry9i0	89	19	.	.	.
cord-104223-ht3ry9i0	90	1	Clusters	cluster	NNS
cord-104223-ht3ry9i0	90	2	were	be	VBD
cord-104223-ht3ry9i0	90	3	washed	wash	VBN
cord-104223-ht3ry9i0	90	4	with	with	IN
cord-104223-ht3ry9i0	90	5	0.1	0.1	CD
cord-104223-ht3ry9i0	90	6	M	M	NNP
cord-104223-ht3ry9i0	90	7	Na	Na	NNP
cord-104223-ht3ry9i0	90	8	cacodylate	cacodylate	NN
cord-104223-ht3ry9i0	90	9	,	,	,
cord-104223-ht3ry9i0	90	10	pH	pH	NNP
cord-104223-ht3ry9i0	90	11	7.4	7.4	CD
cord-104223-ht3ry9i0	90	12	,	,	,
cord-104223-ht3ry9i0	90	13	osmicated	osmicate	VBN
cord-104223-ht3ry9i0	90	14	in	in	IN
cord-104223-ht3ry9i0	90	15	2	2	CD
cord-104223-ht3ry9i0	90	16	%	%	NN
cord-104223-ht3ry9i0	90	17	OsO4	oso4	IN
cord-104223-ht3ry9i0	90	18	in	in	IN
cord-104223-ht3ry9i0	90	19	0.05	0.05	CD
cord-104223-ht3ry9i0	90	20	M	M	NNP
cord-104223-ht3ry9i0	90	21	Na	Na	NNP
cord-104223-ht3ry9i0	90	22	cacodylate	cacodylate	NN
cord-104223-ht3ry9i0	90	23	,	,	,
cord-104223-ht3ry9i0	90	24	pH	pH	NNP
cord-104223-ht3ry9i0	90	25	7.4	7.4	CD
cord-104223-ht3ry9i0	90	26	,	,	,
cord-104223-ht3ry9i0	90	27	for	for	IN
cord-104223-ht3ry9i0	90	28	1	1	CD
cord-104223-ht3ry9i0	90	29	h	h	NN
cord-104223-ht3ry9i0	90	30	,	,	,
cord-104223-ht3ry9i0	90	31	and	and	CC
cord-104223-ht3ry9i0	90	32	then	then	RB
cord-104223-ht3ry9i0	90	33	dehydrated	dehydrate	VBN
cord-104223-ht3ry9i0	90	34	and	and	CC
cord-104223-ht3ry9i0	90	35	embedded	embed	VBN
cord-104223-ht3ry9i0	90	36	as	as	IN
cord-104223-ht3ry9i0	90	37	described	describe	VBN
cord-104223-ht3ry9i0	90	38	above	above	RB
cord-104223-ht3ry9i0	90	39	.	.	.
cord-104223-ht3ry9i0	91	1	Thin	thin	JJ
cord-104223-ht3ry9i0	91	2	sections	section	NNS
cord-104223-ht3ry9i0	91	3	(	(	-LRB-
cord-104223-ht3ry9i0	91	4	80	80	CD
cord-104223-ht3ry9i0	91	5	-	-	SYM
cord-104223-ht3ry9i0	91	6	100	100	CD
cord-104223-ht3ry9i0	91	7	nm	nm	NN
cord-104223-ht3ry9i0	91	8	)	)	-RRB-
cord-104223-ht3ry9i0	91	9	were	be	VBD
cord-104223-ht3ry9i0	91	10	cut	cut	VBN
cord-104223-ht3ry9i0	91	11	and	and	CC
cord-104223-ht3ry9i0	91	12	stained	stain	VBN
cord-104223-ht3ry9i0	91	13	with	with	IN
cord-104223-ht3ry9i0	91	14	2	2	CD
cord-104223-ht3ry9i0	91	15	%	%	NN
cord-104223-ht3ry9i0	91	16	uranyl	uranyl	NN
cord-104223-ht3ry9i0	91	17	acetate	acetate	NN
cord-104223-ht3ry9i0	91	18	followed	follow	VBN
cord-104223-ht3ry9i0	91	19	by	by	IN
cord-104223-ht3ry9i0	91	20	lead	lead	NN
cord-104223-ht3ry9i0	91	21	nitrate	nitrate	NN
cord-104223-ht3ry9i0	91	22	before	before	IN
cord-104223-ht3ry9i0	91	23	visualization	visualization	NN
cord-104223-ht3ry9i0	91	24	on	on	IN
cord-104223-ht3ry9i0	91	25	a	a	DT
cord-104223-ht3ry9i0	91	26	transmission	transmission	NN
cord-104223-ht3ry9i0	91	27	electron	electron	NN
cord-104223-ht3ry9i0	91	28	microscope	microscope	NN
cord-104223-ht3ry9i0	91	29	(	(	-LRB-
cord-104223-ht3ry9i0	91	30	410	410	CD
cord-104223-ht3ry9i0	91	31	;	;	:
cord-104223-ht3ry9i0	91	32	Philips	Philips	NNP
cord-104223-ht3ry9i0	91	33	Electronic	Electronic	NNP
cord-104223-ht3ry9i0	91	34	Instruments	Instruments	NNPS
cord-104223-ht3ry9i0	91	35	,	,	,
cord-104223-ht3ry9i0	91	36	Inc.	Inc.	NNP
cord-104223-ht3ry9i0	91	37	)	)	-RRB-
cord-104223-ht3ry9i0	91	38	.	.	.
cord-104223-ht3ry9i0	92	1	Bag	bag	NN
cord-104223-ht3ry9i0	92	2	cell	cell	NN
cord-104223-ht3ry9i0	92	3	clusters	cluster	NNS
cord-104223-ht3ry9i0	92	4	or	or	CC
cord-104223-ht3ry9i0	92	5	atrial	atrial	JJ
cord-104223-ht3ry9i0	92	6	gland	gland	NN
cord-104223-ht3ry9i0	92	7	pieces	piece	NNS
cord-104223-ht3ry9i0	92	8	were	be	VBD
cord-104223-ht3ry9i0	92	9	incubated	incubate	VBN
cord-104223-ht3ry9i0	92	10	in	in	IN
cord-104223-ht3ry9i0	92	11	10	10	CD
cord-104223-ht3ry9i0	92	12	#	#	NN
cord-104223-ht3ry9i0	92	13	M	m	NN
cord-104223-ht3ry9i0	92	14	monensin	monensin	NNP
cord-104223-ht3ry9i0	92	15	(	(	-LRB-
cord-104223-ht3ry9i0	92	16	Sigma	Sigma	NNP
cord-104223-ht3ry9i0	92	17	Chemical	Chemical	NNP
cord-104223-ht3ry9i0	92	18	Co.	Co.	NNP
cord-104223-ht3ry9i0	92	19	)	)	-RRB-
cord-104223-ht3ry9i0	92	20	for	for	IN
cord-104223-ht3ry9i0	92	21	2	2	CD
cord-104223-ht3ry9i0	92	22	h	h	NN
cord-104223-ht3ry9i0	92	23	in	in	IN
cord-104223-ht3ry9i0	92	24	ASW	ASW	NNP
cord-104223-ht3ry9i0	92	25	with	with	IN
cord-104223-ht3ry9i0	92	26	1	1	CD
cord-104223-ht3ry9i0	92	27	%	%	NN
cord-104223-ht3ry9i0	92	28	ethanol	ethanol	NN
cord-104223-ht3ry9i0	92	29	at	at	IN
cord-104223-ht3ry9i0	92	30	14	14	CD
cord-104223-ht3ry9i0	92	31	°	°	NN
cord-104223-ht3ry9i0	92	32	C	c	NN
cord-104223-ht3ry9i0	92	33	.	.	.
cord-104223-ht3ry9i0	93	1	Control	control	NN
cord-104223-ht3ry9i0	93	2	experiments	experiment	NNS
cord-104223-ht3ry9i0	93	3	with	with	IN
cord-104223-ht3ry9i0	93	4	ASW	ASW	NNP
cord-104223-ht3ry9i0	93	5	and	and	CC
cord-104223-ht3ry9i0	93	6	1	1	CD
cord-104223-ht3ry9i0	93	7	%	%	NN
cord-104223-ht3ry9i0	93	8	ethanol	ethanol	NN
cord-104223-ht3ry9i0	93	9	alone	alone	RB
cord-104223-ht3ry9i0	93	10	showed	show	VBD
cord-104223-ht3ry9i0	93	11	no	no	DT
cord-104223-ht3ry9i0	93	12	effect	effect	NN
cord-104223-ht3ry9i0	93	13	on	on	IN
cord-104223-ht3ry9i0	93	14	the	the	DT
cord-104223-ht3ry9i0	93	15	bag	bag	NN
cord-104223-ht3ry9i0	93	16	cells	cell	NNS
cord-104223-ht3ry9i0	93	17	.	.	.
cord-104223-ht3ry9i0	94	1	After	after	IN
cord-104223-ht3ry9i0	94	2	the	the	DT
cord-104223-ht3ry9i0	94	3	2-h	2-h	CD
cord-104223-ht3ry9i0	94	4	preincubation	preincubation	NN
cord-104223-ht3ry9i0	94	5	,	,	,
cord-104223-ht3ry9i0	94	6	clusters	cluster	NNS
cord-104223-ht3ry9i0	94	7	were	be	VBD
cord-104223-ht3ry9i0	94	8	labeled	label	VBN
cord-104223-ht3ry9i0	94	9	with	with	IN
cord-104223-ht3ry9i0	94	10	tritiated	tritiate	VBN
cord-104223-ht3ry9i0	94	11	amino	amino	JJ
cord-104223-ht3ry9i0	94	12	acids	acid	NNS
cord-104223-ht3ry9i0	94	13	as	as	IN
cord-104223-ht3ry9i0	94	14	described	describe	VBN
cord-104223-ht3ry9i0	94	15	above	above	RB
cord-104223-ht3ry9i0	94	16	.	.	.
cord-104223-ht3ry9i0	95	1	All	all	DT
cord-104223-ht3ry9i0	95	2	incubations	incubation	NNS
cord-104223-ht3ry9i0	95	3	and	and	CC
cord-104223-ht3ry9i0	95	4	washes	wash	NNS
cord-104223-ht3ry9i0	95	5	were	be	VBD
cord-104223-ht3ry9i0	95	6	done	do	VBN
cord-104223-ht3ry9i0	95	7	in	in	IN
cord-104223-ht3ry9i0	95	8	the	the	DT
cord-104223-ht3ry9i0	95	9	presence	presence	NN
cord-104223-ht3ry9i0	95	10	of	of	IN
cord-104223-ht3ry9i0	95	11	10	10	CD
cord-104223-ht3ry9i0	95	12	#	#	NN
cord-104223-ht3ry9i0	95	13	M	M	NNP
cord-104223-ht3ry9i0	95	14	monensin	monensin	NNP
cord-104223-ht3ry9i0	95	15	and	and	CC
cord-104223-ht3ry9i0	95	16	1	1	CD
cord-104223-ht3ry9i0	95	17	%	%	NN
cord-104223-ht3ry9i0	95	18	EtOH	EtOH	NNP
cord-104223-ht3ry9i0	95	19	or	or	CC
cord-104223-ht3ry9i0	95	20	1	1	CD
cord-104223-ht3ry9i0	95	21	%	%	NN
cord-104223-ht3ry9i0	95	22	EtOH	EtOH	NNP
cord-104223-ht3ry9i0	95	23	alone	alone	JJ
cord-104223-ht3ry9i0	95	24	.	.	.
cord-104223-ht3ry9i0	96	1	The	the	DT
cord-104223-ht3ry9i0	96	2	clusters	cluster	NNS
cord-104223-ht3ry9i0	96	3	were	be	VBD
cord-104223-ht3ry9i0	96	4	then	then	RB
cord-104223-ht3ry9i0	96	5	processed	process	VBN
cord-104223-ht3ry9i0	96	6	for	for	IN
cord-104223-ht3ry9i0	96	7	EM	em	NN
cord-104223-ht3ry9i0	96	8	immunohistochemistry	immunohistochemistry	FW
cord-104223-ht3ry9i0	96	9	(	(	-LRB-
cord-104223-ht3ry9i0	96	10	Fisher	Fisher	NNP
cord-104223-ht3ry9i0	96	11	et	et	NNP
cord-104223-ht3ry9i0	96	12	ai	ai	NNP
cord-104223-ht3ry9i0	96	13	.	.	NNP
cord-104223-ht3ry9i0	96	14	,	,	,
cord-104223-ht3ry9i0	96	15	1988	1988	CD
cord-104223-ht3ry9i0	96	16	)	)	-RRB-
cord-104223-ht3ry9i0	96	17	,	,	,
cord-104223-ht3ry9i0	96	18	autoradiography	autoradiography	NNP
cord-104223-ht3ry9i0	96	19	(	(	-LRB-
cord-104223-ht3ry9i0	96	20	described	describe	VBN
cord-104223-ht3ry9i0	96	21	above	above	IN
cord-104223-ht3ry9i0	96	22	)	)	-RRB-
cord-104223-ht3ry9i0	96	23	,	,	,
cord-104223-ht3ry9i0	96	24	or	or	CC
cord-104223-ht3ry9i0	96	25	SDS	SDS	NNP
cord-104223-ht3ry9i0	96	26	-	-	HYPH
cord-104223-ht3ry9i0	96	27	nrea	nrea	NNP
cord-104223-ht3ry9i0	96	28	gels	gel	NNS
cord-104223-ht3ry9i0	96	29	.	.	.
cord-104223-ht3ry9i0	97	1	In	in	IN
cord-104223-ht3ry9i0	97	2	the	the	DT
cord-104223-ht3ry9i0	97	3	monensin	monensin	NNP
cord-104223-ht3ry9i0	97	4	EM	EM	NNP
cord-104223-ht3ry9i0	97	5	autoradiography	autoradiography	NNP
cord-104223-ht3ry9i0	98	1	~periment	~periment	NNP
cord-104223-ht3ry9i0	98	2	,	,	,
cord-104223-ht3ry9i0	98	3	quantitation	quantitation	NNP
cord-104223-ht3ry9i0	98	4	was	be	VBD
cord-104223-ht3ry9i0	98	5	similar	similar	JJ
cord-104223-ht3ry9i0	98	6	to	to	IN
cord-104223-ht3ry9i0	98	7	that	that	DT
cord-104223-ht3ry9i0	98	8	already	already	RB
cord-104223-ht3ry9i0	98	9	described	describe	VBN
cord-104223-ht3ry9i0	98	10	,	,	,
cord-104223-ht3ry9i0	98	11	but	but	CC
cord-104223-ht3ry9i0	98	12	different	different	JJ
cord-104223-ht3ry9i0	98	13	compartments	compartment	NNS
cord-104223-ht3ry9i0	98	14	were	be	VBD
cord-104223-ht3ry9i0	98	15	used	use	VBN
cord-104223-ht3ry9i0	98	16	.	.	.
cord-104223-ht3ry9i0	99	1	The	the	DT
cord-104223-ht3ry9i0	99	2	compartments	compartment	NNS
cord-104223-ht3ry9i0	99	3	measured	measure	VBN
cord-104223-ht3ry9i0	99	4	in	in	IN
cord-104223-ht3ry9i0	99	5	the	the	DT
cord-104223-ht3ry9i0	99	6	monensin	monensin	JJ
cord-104223-ht3ry9i0	99	7	experiment	experiment	NN
cord-104223-ht3ry9i0	99	8	were	be	VBD
cord-104223-ht3ry9i0	99	9	ER	ER	NNP
cord-104223-ht3ry9i0	99	10	,	,	,
cord-104223-ht3ry9i0	99	11	vacuoles	vacuole	NNS
cord-104223-ht3ry9i0	99	12	,	,	,
cord-104223-ht3ry9i0	99	13	vacuoles	vacuole	NNS
cord-104223-ht3ry9i0	99	14	with	with	IN
cord-104223-ht3ry9i0	99	15	densities	density	NNS
cord-104223-ht3ry9i0	99	16	,	,	,
cord-104223-ht3ry9i0	99	17	densities	density	NNS
cord-104223-ht3ry9i0	99	18	in	in	IN
cord-104223-ht3ry9i0	99	19	vacuoles	vacuole	NNS
cord-104223-ht3ry9i0	99	20	,	,	,
cord-104223-ht3ry9i0	99	21	dense	dense	JJ
cord-104223-ht3ry9i0	99	22	core	core	NN
cord-104223-ht3ry9i0	99	23	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	99	24	,	,	,
cord-104223-ht3ry9i0	99	25	mitochondria	mitochondrion	NNS
cord-104223-ht3ry9i0	99	26	,	,	,
cord-104223-ht3ry9i0	99	27	iysosomes	iysosomes	NNP
cord-104223-ht3ry9i0	99	28	,	,	,
cord-104223-ht3ry9i0	99	29	nucleus	nucleus	NN
cord-104223-ht3ry9i0	99	30	,	,	,
cord-104223-ht3ry9i0	99	31	and	and	CC
cord-104223-ht3ry9i0	99	32	cytoplasm	cytoplasm	NN
cord-104223-ht3ry9i0	99	33	.	.	.
cord-104223-ht3ry9i0	100	1	A	a	DT
cord-104223-ht3ry9i0	100	2	separate	separate	JJ
cord-104223-ht3ry9i0	100	3	compartment	compartment	NN
cord-104223-ht3ry9i0	100	4	,	,	,
cord-104223-ht3ry9i0	100	5	vacuolar	vacuolar	NNP
cord-104223-ht3ry9i0	100	6	membranes	membrane	NNS
cord-104223-ht3ry9i0	100	7	,	,	,
cord-104223-ht3ry9i0	100	8	was	be	VBD
cord-104223-ht3ry9i0	100	9	calculated	calculate	VBN
cord-104223-ht3ry9i0	100	10	in	in	IN
cord-104223-ht3ry9i0	100	11	the	the	DT
cord-104223-ht3ry9i0	100	12	entry	entry	NN
cord-104223-ht3ry9i0	100	13	algorithm	algorithm	NN
cord-104223-ht3ry9i0	100	14	.	.	.
cord-104223-ht3ry9i0	101	1	As	as	IN
cord-104223-ht3ry9i0	101	2	the	the	DT
cord-104223-ht3ry9i0	101	3	vacuoles	vacuole	NNS
cord-104223-ht3ry9i0	101	4	curve	curve	VBP
cord-104223-ht3ry9i0	101	5	through	through	IN
cord-104223-ht3ry9i0	101	6	the	the	DT
cord-104223-ht3ry9i0	101	7	thickness	thickness	NN
cord-104223-ht3ry9i0	101	8	of	of	IN
cord-104223-ht3ry9i0	101	9	the	the	DT
cord-104223-ht3ry9i0	101	10	section	section	NN
cord-104223-ht3ry9i0	101	11	,	,	,
cord-104223-ht3ry9i0	101	12	a	a	DT
cord-104223-ht3ry9i0	101	13	50-nm	50-nm	CD
cord-104223-ht3ry9i0	101	14	distance	distance	NN
cord-104223-ht3ry9i0	101	15	was	be	VBD
cord-104223-ht3ry9i0	101	16	used	use	VBN
cord-104223-ht3ry9i0	101	17	to	to	TO
cord-104223-ht3ry9i0	101	18	define	define	VB
cord-104223-ht3ry9i0	101	19	the	the	DT
cord-104223-ht3ry9i0	101	20	limit	limit	NN
cord-104223-ht3ry9i0	101	21	of	of	IN
cord-104223-ht3ry9i0	101	22	the	the	DT
cord-104223-ht3ry9i0	101	23	membrane	membrane	NN
cord-104223-ht3ry9i0	101	24	in	in	IN
cord-104223-ht3ry9i0	101	25	these	these	DT
cord-104223-ht3ry9i0	101	26	calculations	calculation	NNS
cord-104223-ht3ry9i0	101	27	.	.	.
cord-104223-ht3ry9i0	102	1	Also	also	RB
cord-104223-ht3ry9i0	102	2	,	,	,
cord-104223-ht3ry9i0	102	3	for	for	IN
cord-104223-ht3ry9i0	102	4	quantitating	quantitate	VBG
cord-104223-ht3ry9i0	102	5	monensin	monensin	JJ
cord-104223-ht3ry9i0	102	6	experiments	experiment	NNS
cord-104223-ht3ry9i0	102	7	,	,	,
cord-104223-ht3ry9i0	102	8	micrographs	micrograph	NNS
cord-104223-ht3ry9i0	102	9	were	be	VBD
cord-104223-ht3ry9i0	102	10	taken	take	VBN
cord-104223-ht3ry9i0	102	11	at	at	IN
cord-104223-ht3ry9i0	102	12	12,000x	12,000x	RB
cord-104223-ht3ry9i0	102	13	magnified	magnify	VBN
cord-104223-ht3ry9i0	102	14	to	to	IN
cord-104223-ht3ry9i0	102	15	32,000	32,000	CD
cord-104223-ht3ry9i0	102	16	x.	x.	NN
cord-104223-ht3ry9i0	102	17	Clusters	cluster	NNS
cord-104223-ht3ry9i0	102	18	were	be	VBD
cord-104223-ht3ry9i0	102	19	labeled	label	VBN
cord-104223-ht3ry9i0	102	20	as	as	IN
cord-104223-ht3ry9i0	102	21	described	describe	VBN
cord-104223-ht3ry9i0	102	22	.	.	.
cord-104223-ht3ry9i0	103	1	The	the	DT
cord-104223-ht3ry9i0	103	2	gels	gel	NNS
cord-104223-ht3ry9i0	103	3	were	be	VBD
cord-104223-ht3ry9i0	103	4	quantitated	quantitate	VBN
cord-104223-ht3ry9i0	103	5	by	by	IN
cord-104223-ht3ry9i0	103	6	densitometry	densitometry	NN
cord-104223-ht3ry9i0	103	7	of	of	IN
cord-104223-ht3ry9i0	103	8	the	the	DT
cord-104223-ht3ry9i0	103	9	x	x	NN
cord-104223-ht3ry9i0	103	10	-	-	NN
cord-104223-ht3ry9i0	103	11	ray	ray	NNP
cord-104223-ht3ry9i0	103	12	film	film	NN
cord-104223-ht3ry9i0	103	13	.	.	.
cord-104223-ht3ry9i0	104	1	Figure	figure	NN
cord-104223-ht3ry9i0	104	2	1	1	CD
cord-104223-ht3ry9i0	104	3	.	.	.
cord-104223-ht3ry9i0	105	1	Proteolytic	proteolytic	JJ
cord-104223-ht3ry9i0	105	2	processing	processing	NN
cord-104223-ht3ry9i0	105	3	of	of	IN
cord-104223-ht3ry9i0	105	4	the	the	DT
cord-104223-ht3ry9i0	105	5	ELH	ELH	NNP
cord-104223-ht3ry9i0	105	6	prohormone	prohormone	NN
cord-104223-ht3ry9i0	105	7	.	.	.
cord-104223-ht3ry9i0	106	1	A	a	DT
cord-104223-ht3ry9i0	106	2	schematic	schematic	NN
cord-104223-ht3ry9i0	106	3	of	of	IN
cord-104223-ht3ry9i0	106	4	the	the	DT
cord-104223-ht3ry9i0	106	5	242-amino	242-amino	CD
cord-104223-ht3ry9i0	106	6	acid	acid	NN
cord-104223-ht3ry9i0	106	7	ELH	ELH	NNP
cord-104223-ht3ry9i0	106	8	prohormone	prohormone	NN
cord-104223-ht3ry9i0	106	9	is	be	VBZ
cord-104223-ht3ry9i0	106	10	shown	show	VBN
cord-104223-ht3ry9i0	106	11	including	include	VBG
cord-104223-ht3ry9i0	106	12	a	a	DT
cord-104223-ht3ry9i0	106	13	29-amino	29-amino	CD
cord-104223-ht3ry9i0	106	14	acid	acid	NN
cord-104223-ht3ry9i0	106	15	signal	signal	NN
cord-104223-ht3ry9i0	106	16	sequence	sequence	NN
cord-104223-ht3ry9i0	106	17	(	(	-LRB-
cord-104223-ht3ry9i0	106	18	horizontal	horizontal	JJ
cord-104223-ht3ry9i0	106	19	black	black	JJ
cord-104223-ht3ry9i0	106	20	bars	bar	NNS
cord-104223-ht3ry9i0	106	21	)	)	-RRB-
cord-104223-ht3ry9i0	106	22	.	.	.
cord-104223-ht3ry9i0	107	1	Four	four	CD
cord-104223-ht3ry9i0	107	2	biologically	biologically	RB
cord-104223-ht3ry9i0	107	3	active	active	JJ
cord-104223-ht3ry9i0	107	4	bag	bag	NN
cord-104223-ht3ry9i0	107	5	cell	cell	NN
cord-104223-ht3ry9i0	107	6	peptides	peptide	NNS
cord-104223-ht3ry9i0	107	7	,	,	,
cord-104223-ht3ry9i0	107	8	the	the	DT
cord-104223-ht3ry9i0	107	9	c~,/3	c~,/3	NN
cord-104223-ht3ry9i0	107	10	,	,	,
cord-104223-ht3ry9i0	107	11	and	and	CC
cord-104223-ht3ry9i0	107	12	3	3	CD
cord-104223-ht3ry9i0	107	13	,	,	,
cord-104223-ht3ry9i0	107	14	bag	bag	NN
cord-104223-ht3ry9i0	107	15	cell	cell	NN
cord-104223-ht3ry9i0	107	16	peptides	peptide	NNS
cord-104223-ht3ry9i0	107	17	as	as	RB
cord-104223-ht3ry9i0	107	18	well	well	RB
cord-104223-ht3ry9i0	107	19	as	as	IN
cord-104223-ht3ry9i0	107	20	ELH	ELH	NNP
cord-104223-ht3ry9i0	107	21	,	,	,
cord-104223-ht3ry9i0	107	22	are	be	VBP
cord-104223-ht3ry9i0	107	23	shaded	shaded	JJ
cord-104223-ht3ry9i0	107	24	.	.	.
cord-104223-ht3ry9i0	108	1	Vertical	vertical	JJ
cord-104223-ht3ry9i0	108	2	bars	bar	NNS
cord-104223-ht3ry9i0	108	3	are	be	VBP
cord-104223-ht3ry9i0	108	4	sequences	sequence	NNS
cord-104223-ht3ry9i0	108	5	of	of	IN
cord-104223-ht3ry9i0	108	6	basic	basic	JJ
cord-104223-ht3ry9i0	108	7	residues	residue	NNS
cord-104223-ht3ry9i0	108	8	used	use	VBN
cord-104223-ht3ry9i0	108	9	as	as	IN
cord-104223-ht3ry9i0	108	10	proteolytic	proteolytic	JJ
cord-104223-ht3ry9i0	108	11	processing	processing	NN
cord-104223-ht3ry9i0	108	12	sites	site	NNS
cord-104223-ht3ry9i0	108	13	.	.	.
cord-104223-ht3ry9i0	109	1	The	the	DT
cord-104223-ht3ry9i0	109	2	first	first	JJ
cord-104223-ht3ry9i0	109	3	cleavage	cleavage	NN
cord-104223-ht3ry9i0	109	4	of	of	IN
cord-104223-ht3ry9i0	109	5	the	the	DT
cord-104223-ht3ry9i0	109	6	prohormone	prohormone	NN
cord-104223-ht3ry9i0	109	7	occurs	occur	VBZ
cord-104223-ht3ry9i0	109	8	at	at	IN
cord-104223-ht3ry9i0	109	9	a	a	DT
cord-104223-ht3ry9i0	109	10	tetrabasic	tetrabasic	NN
cord-104223-ht3ry9i0	109	11	sequence	sequence	NN
cord-104223-ht3ry9i0	109	12	Arg	arg	NN
cord-104223-ht3ry9i0	109	13	-	-	HYPH
cord-104223-ht3ry9i0	109	14	Arg	Arg	NNP
cord-104223-ht3ry9i0	109	15	-	-	HYPH
cord-104223-ht3ry9i0	109	16	Lys	Lys	NNP
cord-104223-ht3ry9i0	109	17	-	-	HYPH
cord-104223-ht3ry9i0	109	18	Arg	Arg	NNP
cord-104223-ht3ry9i0	109	19	,	,	,
cord-104223-ht3ry9i0	109	20	and	and	CC
cord-104223-ht3ry9i0	109	21	the	the	DT
cord-104223-ht3ry9i0	109	22	pathway	pathway	NN
cord-104223-ht3ry9i0	109	23	then	then	RB
cord-104223-ht3ry9i0	109	24	proceeds	proceed	VBZ
cord-104223-ht3ry9i0	109	25	as	as	IN
cord-104223-ht3ry9i0	109	26	shown	show	VBN
cord-104223-ht3ry9i0	109	27	,	,	,
cord-104223-ht3ry9i0	109	28	leading	lead	VBG
cord-104223-ht3ry9i0	109	29	to	to	IN
cord-104223-ht3ry9i0	109	30	the	the	DT
cord-104223-ht3ry9i0	109	31	final	final	JJ
cord-104223-ht3ry9i0	109	32	set	set	NN
cord-104223-ht3ry9i0	109	33	of	of	IN
cord-104223-ht3ry9i0	109	34	product	product	NN
cord-104223-ht3ry9i0	109	35	peptides	peptide	NNS
cord-104223-ht3ry9i0	109	36	shown	show	VBN
cord-104223-ht3ry9i0	109	37	.	.	.
cord-104223-ht3ry9i0	110	1	The	the	DT
cord-104223-ht3ry9i0	110	2	peptides	peptide	NNS
cord-104223-ht3ry9i0	110	3	amino	amino	NNS
cord-104223-ht3ry9i0	110	4	terminal	terminal	JJ
cord-104223-ht3ry9i0	110	5	to	to	IN
cord-104223-ht3ry9i0	110	6	the	the	DT
cord-104223-ht3ry9i0	110	7	first	first	JJ
cord-104223-ht3ry9i0	110	8	cleavage	cleavage	NN
cord-104223-ht3ry9i0	110	9	are	be	VBP
cord-104223-ht3ry9i0	110	10	packaged	package	VBN
cord-104223-ht3ry9i0	110	11	into	into	IN
cord-104223-ht3ry9i0	110	12	one	one	CD
cord-104223-ht3ry9i0	110	13	set	set	NN
cord-104223-ht3ry9i0	110	14	of	of	IN
cord-104223-ht3ry9i0	110	15	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	110	16	,	,	,
cord-104223-ht3ry9i0	110	17	and	and	CC
cord-104223-ht3ry9i0	110	18	the	the	DT
cord-104223-ht3ry9i0	110	19	peptides	peptide	NNS
cord-104223-ht3ry9i0	110	20	carboxy	carboxy	NN
cord-104223-ht3ry9i0	110	21	terminal	terminal	NN
cord-104223-ht3ry9i0	110	22	to	to	IN
cord-104223-ht3ry9i0	110	23	this	this	DT
cord-104223-ht3ry9i0	110	24	cleavage	cleavage	NN
cord-104223-ht3ry9i0	110	25	are	be	VBP
cord-104223-ht3ry9i0	110	26	packaged	package	VBN
cord-104223-ht3ry9i0	110	27	in	in	IN
cord-104223-ht3ry9i0	110	28	a	a	DT
cord-104223-ht3ry9i0	110	29	distinct	distinct	JJ
cord-104223-ht3ry9i0	110	30	vesicle	vesicle	NN
cord-104223-ht3ry9i0	110	31	class	class	NN
cord-104223-ht3ry9i0	110	32	.	.	.
cord-104223-ht3ry9i0	111	1	Above	above	IN
cord-104223-ht3ry9i0	111	2	the	the	DT
cord-104223-ht3ry9i0	111	3	schematic	schematic	NN
cord-104223-ht3ry9i0	111	4	are	be	VBP
cord-104223-ht3ry9i0	111	5	the	the	DT
cord-104223-ht3ry9i0	111	6	positions	position	NNS
cord-104223-ht3ry9i0	111	7	of	of	IN
cord-104223-ht3ry9i0	111	8	the	the	DT
cord-104223-ht3ry9i0	111	9	peptides	peptide	NNS
cord-104223-ht3ry9i0	111	10	used	use	VBN
cord-104223-ht3ry9i0	111	11	to	to	TO
cord-104223-ht3ry9i0	111	12	raise	raise	VB
cord-104223-ht3ry9i0	111	13	antisera	antisera	NN
cord-104223-ht3ry9i0	111	14	used	use	VBN
cord-104223-ht3ry9i0	111	15	in	in	IN
cord-104223-ht3ry9i0	111	16	immunohistochemical	immunohistochemical	JJ
cord-104223-ht3ry9i0	111	17	experiments	experiment	NNS
cord-104223-ht3ry9i0	111	18	.	.	.
cord-104223-ht3ry9i0	112	1	The	the	DT
cord-104223-ht3ry9i0	112	2	top	top	NN
cord-104223-ht3ry9i0	112	3	of	of	IN
cord-104223-ht3ry9i0	112	4	the	the	DT
cord-104223-ht3ry9i0	112	5	figure	figure	NN
cord-104223-ht3ry9i0	112	6	shows	show	VBZ
cord-104223-ht3ry9i0	112	7	the	the	DT
cord-104223-ht3ry9i0	112	8	distribution	distribution	NN
cord-104223-ht3ry9i0	112	9	of	of	IN
cord-104223-ht3ry9i0	112	10	the	the	DT
cord-104223-ht3ry9i0	112	11	amino	amino	NN
cord-104223-ht3ry9i0	112	12	acids	acid	NNS
cord-104223-ht3ry9i0	112	13	-	-	:
cord-104223-ht3ry9i0	112	14	leucine	leucine	NN
cord-104223-ht3ry9i0	112	15	(	(	-LRB-
cord-104223-ht3ry9i0	112	16	L	L	NNP
cord-104223-ht3ry9i0	112	17	)	)	-RRB-
cord-104223-ht3ry9i0	112	18	,	,	,
cord-104223-ht3ry9i0	112	19	isoleucine	isoleucine	NNP
cord-104223-ht3ry9i0	112	20	(	(	-LRB-
cord-104223-ht3ry9i0	112	21	I	i	NN
cord-104223-ht3ry9i0	112	22	)	)	-RRB-
cord-104223-ht3ry9i0	112	23	,	,	,
cord-104223-ht3ry9i0	112	24	and	and	CC
cord-104223-ht3ry9i0	112	25	phenylalanine	phenylalanine	NN
cord-104223-ht3ry9i0	112	26	(	(	-LRB-
cord-104223-ht3ry9i0	112	27	F)-within	F)-within	NNP
cord-104223-ht3ry9i0	112	28	the	the	DT
cord-104223-ht3ry9i0	112	29	prophormone	prophormone	NN
cord-104223-ht3ry9i0	112	30	's	's	POS
cord-104223-ht3ry9i0	112	31	sequence	sequence	NN
cord-104223-ht3ry9i0	112	32	.	.	.
cord-104223-ht3ry9i0	113	1	ELH	ELH	NNP
cord-104223-ht3ry9i0	113	2	precursor	precursor	NN
cord-104223-ht3ry9i0	113	3	must	must	MD
cord-104223-ht3ry9i0	113	4	occur	occur	VB
cord-104223-ht3ry9i0	113	5	after	after	IN
cord-104223-ht3ry9i0	113	6	the	the	DT
cord-104223-ht3ry9i0	113	7	initial	initial	JJ
cord-104223-ht3ry9i0	113	8	cleavage	cleavage	NN
cord-104223-ht3ry9i0	113	9	of	of	IN
cord-104223-ht3ry9i0	113	10	the	the	DT
cord-104223-ht3ry9i0	113	11	prohormone	prohormone	NN
cord-104223-ht3ry9i0	113	12	.	.	.
cord-104223-ht3ry9i0	114	1	To	to	TO
cord-104223-ht3ry9i0	114	2	determine	determine	VB
cord-104223-ht3ry9i0	114	3	the	the	DT
cord-104223-ht3ry9i0	114	4	intracellular	intracellular	JJ
cord-104223-ht3ry9i0	114	5	site	site	NN
cord-104223-ht3ry9i0	114	6	of	of	IN
cord-104223-ht3ry9i0	114	7	various	various	JJ
cord-104223-ht3ry9i0	114	8	cleavages	cleavage	NNS
cord-104223-ht3ry9i0	114	9	,	,	,
cord-104223-ht3ry9i0	114	10	we	-PRON-	PRP
cord-104223-ht3ry9i0	114	11	have	have	VBP
cord-104223-ht3ry9i0	114	12	correlated	correlate	VBN
cord-104223-ht3ry9i0	114	13	the	the	DT
cord-104223-ht3ry9i0	114	14	extent	extent	NN
cord-104223-ht3ry9i0	114	15	of	of	IN
cord-104223-ht3ry9i0	114	16	prohormone	prohormone	NN
cord-104223-ht3ry9i0	114	17	endoproteolytic	endoproteolytic	JJ
cord-104223-ht3ry9i0	114	18	cleavage	cleavage	NN
cord-104223-ht3ry9i0	114	19	with	with	IN
cord-104223-ht3ry9i0	114	20	the	the	DT
cord-104223-ht3ry9i0	114	21	location	location	NN
cord-104223-ht3ry9i0	114	22	of	of	IN
cord-104223-ht3ry9i0	114	23	the	the	DT
cord-104223-ht3ry9i0	114	24	molecule	molecule	NN
cord-104223-ht3ry9i0	114	25	within	within	IN
cord-104223-ht3ry9i0	114	26	the	the	DT
cord-104223-ht3ry9i0	114	27	secretory	secretory	JJ
cord-104223-ht3ry9i0	114	28	pathway	pathway	NN
cord-104223-ht3ry9i0	114	29	.	.	.
cord-104223-ht3ry9i0	115	1	Bag	bag	NN
cord-104223-ht3ry9i0	115	2	cell	cell	NN
cord-104223-ht3ry9i0	115	3	clusters	cluster	NNS
cord-104223-ht3ry9i0	115	4	were	be	VBD
cord-104223-ht3ry9i0	115	5	labeled	label	VBN
cord-104223-ht3ry9i0	115	6	with	with	IN
cord-104223-ht3ry9i0	115	7	[	[	-LRB-
cord-104223-ht3ry9i0	115	8	3H]Ile	3h]ile	CD
cord-104223-ht3ry9i0	115	9	to	to	TO
cord-104223-ht3ry9i0	115	10	label	label	VB
cord-104223-ht3ry9i0	115	11	the	the	DT
cord-104223-ht3ry9i0	115	12	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	115	13	-	-	HYPH
cord-104223-ht3ry9i0	115	14	terminal	terminal	NN
cord-104223-ht3ry9i0	115	15	,	,	,
cord-104223-ht3ry9i0	115	16	ELH	ELH	NNP
cord-104223-ht3ry9i0	115	17	-	-	HYPH
cord-104223-ht3ry9i0	115	18	containing	contain	VBG
cord-104223-ht3ry9i0	115	19	side	side	NN
cord-104223-ht3ry9i0	115	20	of	of	IN
cord-104223-ht3ry9i0	115	21	the	the	DT
cord-104223-ht3ry9i0	115	22	prohormone	prohormone	NN
cord-104223-ht3ry9i0	115	23	or	or	CC
cord-104223-ht3ry9i0	115	24	[	[	-LRB-
cord-104223-ht3ry9i0	115	25	3H]Phe	3h]phe	CD
cord-104223-ht3ry9i0	115	26	to	to	TO
cord-104223-ht3ry9i0	115	27	label	label	VB
cord-104223-ht3ry9i0	115	28	the	the	DT
cord-104223-ht3ry9i0	115	29	aminoterminal	aminoterminal	NN
cord-104223-ht3ry9i0	115	30	,	,	,
cord-104223-ht3ry9i0	115	31	bag	bag	NN
cord-104223-ht3ry9i0	115	32	cell	cell	NN
cord-104223-ht3ry9i0	115	33	peptide	peptide	NN
cord-104223-ht3ry9i0	115	34	-	-	HYPH
cord-104223-ht3ry9i0	115	35	containing	contain	VBG
cord-104223-ht3ry9i0	115	36	side	side	NN
cord-104223-ht3ry9i0	115	37	of	of	IN
cord-104223-ht3ry9i0	115	38	the	the	DT
cord-104223-ht3ry9i0	115	39	prohormone	prohormone	NN
cord-104223-ht3ry9i0	115	40	.	.	.
cord-104223-ht3ry9i0	116	1	Acid	acid	NN
cord-104223-ht3ry9i0	116	2	acetone	acetone	NN
cord-104223-ht3ry9i0	116	3	extracts	extract	NNS
cord-104223-ht3ry9i0	116	4	were	be	VBD
cord-104223-ht3ry9i0	116	5	then	then	RB
cord-104223-ht3ry9i0	116	6	fractionated	fractionate	VBN
cord-104223-ht3ry9i0	116	7	on	on	IN
cord-104223-ht3ry9i0	116	8	SDS	sds	NN
cord-104223-ht3ry9i0	116	9	-	-	HYPH
cord-104223-ht3ry9i0	116	10	urea	urea	NN
cord-104223-ht3ry9i0	116	11	polyacrylamide	polyacrylamide	NN
cord-104223-ht3ry9i0	116	12	gels	gel	NNS
cord-104223-ht3ry9i0	116	13	(	(	-LRB-
cord-104223-ht3ry9i0	116	14	Fig	Fig	NNP
cord-104223-ht3ry9i0	116	15	.	.	NNP
cord-104223-ht3ry9i0	116	16	2	2	CD
cord-104223-ht3ry9i0	116	17	,	,	,
cord-104223-ht3ry9i0	116	18	A	A	NNP
cord-104223-ht3ry9i0	116	19	,	,	,
cord-104223-ht3ry9i0	116	20	further	further	JJ
cord-104223-ht3ry9i0	116	21	cleavage	cleavage	NN
cord-104223-ht3ry9i0	116	22	of	of	IN
cord-104223-ht3ry9i0	116	23	the	the	DT
cord-104223-ht3ry9i0	116	24	initial	initial	JJ
cord-104223-ht3ry9i0	116	25	amino	amino	NN
cord-104223-ht3ry9i0	116	26	-	-	HYPH
cord-104223-ht3ry9i0	116	27	terminal	terminal	NN
cord-104223-ht3ry9i0	116	28	intermediate	intermediate	NN
cord-104223-ht3ry9i0	116	29	(	(	-LRB-
cord-104223-ht3ry9i0	116	30	F2	f2	NN
cord-104223-ht3ry9i0	116	31	;	;	:
cord-104223-ht3ry9i0	116	32	Fig	Fig	NNP
cord-104223-ht3ry9i0	116	33	.	.	.
cord-104223-ht3ry9i0	117	1	2	2	LS
cord-104223-ht3ry9i0	117	2	A	a	NN
cord-104223-ht3ry9i0	117	3	)	)	-RRB-
cord-104223-ht3ry9i0	117	4	occurs	occur	VBZ
cord-104223-ht3ry9i0	117	5	more	more	RBR
cord-104223-ht3ry9i0	117	6	slowly	slowly	RB
cord-104223-ht3ry9i0	117	7	than	than	IN
cord-104223-ht3ry9i0	117	8	that	that	DT
cord-104223-ht3ry9i0	117	9	of	of	IN
cord-104223-ht3ry9i0	117	10	the	the	DT
cord-104223-ht3ry9i0	117	11	initial	initial	JJ
cord-104223-ht3ry9i0	117	12	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	117	13	-	-	HYPH
cord-104223-ht3ry9i0	117	14	terminal	terminal	NN
cord-104223-ht3ry9i0	117	15	intermediate	intermediate	JJ
cord-104223-ht3ry9i0	117	16	(	(	-LRB-
cord-104223-ht3ry9i0	117	17	13	13	CD
cord-104223-ht3ry9i0	117	18	;	;	:
cord-104223-ht3ry9i0	117	19	Fig	Fig	NNP
cord-104223-ht3ry9i0	117	20	.	.	.
cord-104223-ht3ry9i0	118	1	2	2	CD
cord-104223-ht3ry9i0	118	2	B	b	NN
cord-104223-ht3ry9i0	118	3	)	)	-RRB-
cord-104223-ht3ry9i0	118	4	.	.	.
cord-104223-ht3ry9i0	119	1	Monensin	Monensin	NNP
cord-104223-ht3ry9i0	119	2	is	be	VBZ
cord-104223-ht3ry9i0	119	3	an	an	DT
cord-104223-ht3ry9i0	119	4	ionophore	ionophore	NN
cord-104223-ht3ry9i0	119	5	that	that	WDT
cord-104223-ht3ry9i0	119	6	blocks	block	VBZ
cord-104223-ht3ry9i0	119	7	the	the	DT
cord-104223-ht3ry9i0	119	8	proteolytic	proteolytic	JJ
cord-104223-ht3ry9i0	119	9	cleavage	cleavage	NN
cord-104223-ht3ry9i0	119	10	of	of	IN
cord-104223-ht3ry9i0	119	11	a	a	DT
cord-104223-ht3ry9i0	119	12	number	number	NN
cord-104223-ht3ry9i0	119	13	of	of	IN
cord-104223-ht3ry9i0	119	14	neuropeptide	neuropeptide	NN
cord-104223-ht3ry9i0	119	15	prohormones	prohormone	NNS
cord-104223-ht3ry9i0	119	16	and	and	CC
cord-104223-ht3ry9i0	119	17	causes	cause	VBZ
cord-104223-ht3ry9i0	119	18	them	-PRON-	PRP
cord-104223-ht3ry9i0	119	19	to	to	TO
cord-104223-ht3ry9i0	119	20	accumulate	accumulate	VB
cord-104223-ht3ry9i0	119	21	in	in	IN
cord-104223-ht3ry9i0	119	22	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	119	23	-	-	HYPH
cord-104223-ht3ry9i0	119	24	related	relate	VBN
cord-104223-ht3ry9i0	119	25	compartments	compartment	NNS
cord-104223-ht3ry9i0	119	26	(	(	-LRB-
cord-104223-ht3ry9i0	119	27	Crine	Crine	NNP
cord-104223-ht3ry9i0	119	28	and	and	CC
cord-104223-ht3ry9i0	119	29	Dufour	Dufour	NNP
cord-104223-ht3ry9i0	119	30	,	,	,
cord-104223-ht3ry9i0	119	31	1982	1982	CD
cord-104223-ht3ry9i0	119	32	;	;	:
cord-104223-ht3ry9i0	119	33	Orci	Orci	NNP
cord-104223-ht3ry9i0	119	34	et	et	NNP
cord-104223-ht3ry9i0	119	35	al	al	NNP
cord-104223-ht3ry9i0	119	36	.	.	NNP
cord-104223-ht3ry9i0	119	37	,	,	,
cord-104223-ht3ry9i0	119	38	1984	1984	CD
cord-104223-ht3ry9i0	119	39	)	)	-RRB-
cord-104223-ht3ry9i0	119	40	.	.	.
cord-104223-ht3ry9i0	120	1	Presumably	presumably	RB
cord-104223-ht3ry9i0	120	2	,	,	,
cord-104223-ht3ry9i0	120	3	the	the	DT
cord-104223-ht3ry9i0	120	4	cleavage	cleavage	NN
cord-104223-ht3ry9i0	120	5	is	be	VBZ
cord-104223-ht3ry9i0	120	6	inhibited	inhibit	VBN
cord-104223-ht3ry9i0	120	7	either	either	CC
cord-104223-ht3ry9i0	120	8	by	by	IN
cord-104223-ht3ry9i0	120	9	blocking	block	VBG
cord-104223-ht3ry9i0	120	10	transport	transport	NN
cord-104223-ht3ry9i0	120	11	of	of	IN
cord-104223-ht3ry9i0	120	12	the	the	DT
cord-104223-ht3ry9i0	120	13	hormone	hormone	NN
cord-104223-ht3ry9i0	120	14	to	to	IN
cord-104223-ht3ry9i0	120	15	the	the	DT
cord-104223-ht3ry9i0	120	16	site	site	NN
cord-104223-ht3ry9i0	120	17	of	of	IN
cord-104223-ht3ry9i0	120	18	cleavage	cleavage	NN
cord-104223-ht3ry9i0	120	19	or	or	CC
cord-104223-ht3ry9i0	120	20	by	by	IN
cord-104223-ht3ry9i0	120	21	disrupting	disrupt	VBG
cord-104223-ht3ry9i0	120	22	necessary	necessary	JJ
cord-104223-ht3ry9i0	120	23	ionic	ionic	JJ
cord-104223-ht3ry9i0	120	24	gradients	gradient	NNS
cord-104223-ht3ry9i0	120	25	.	.	.
cord-104223-ht3ry9i0	121	1	In	in	IN
cord-104223-ht3ry9i0	121	2	contrast	contrast	NN
cord-104223-ht3ry9i0	121	3	to	to	IN
cord-104223-ht3ry9i0	121	4	other	other	JJ
cord-104223-ht3ry9i0	121	5	systems	system	NNS
cord-104223-ht3ry9i0	121	6	,	,	,
cord-104223-ht3ry9i0	121	7	initial	initial	JJ
cord-104223-ht3ry9i0	121	8	cleavage	cleavage	NN
cord-104223-ht3ry9i0	121	9	of	of	IN
cord-104223-ht3ry9i0	121	10	the	the	DT
cord-104223-ht3ry9i0	121	11	ELH	ELH	NNP
cord-104223-ht3ry9i0	121	12	prohormone	prohormone	NN
cord-104223-ht3ry9i0	121	13	still	still	RB
cord-104223-ht3ry9i0	121	14	occurs	occur	VBZ
cord-104223-ht3ry9i0	121	15	after	after	IN
cord-104223-ht3ry9i0	121	16	a	a	DT
cord-104223-ht3ry9i0	121	17	monensin	monensin	JJ
cord-104223-ht3ry9i0	121	18	block	block	NN
cord-104223-ht3ry9i0	121	19	;	;	:
cord-104223-ht3ry9i0	121	20	however	however	RB
cord-104223-ht3ry9i0	121	21	,	,	,
cord-104223-ht3ry9i0	121	22	all	all	DT
cord-104223-ht3ry9i0	121	23	subsequent	subsequent	JJ
cord-104223-ht3ry9i0	121	24	cleavages	cleavage	NNS
cord-104223-ht3ry9i0	121	25	are	be	VBP
cord-104223-ht3ry9i0	121	26	inhibited	inhibit	VBN
cord-104223-ht3ry9i0	121	27	,	,	,
cord-104223-ht3ry9i0	121	28	and	and	CC
cord-104223-ht3ry9i0	121	29	the	the	DT
cord-104223-ht3ry9i0	121	30	two	two	CD
cord-104223-ht3ry9i0	121	31	initial	initial	JJ
cord-104223-ht3ry9i0	121	32	processing	processing	NN
cord-104223-ht3ry9i0	121	33	intermediates	intermediate	NNS
cord-104223-ht3ry9i0	121	34	accumulate	accumulate	VBP
cord-104223-ht3ry9i0	121	35	in	in	IN
cord-104223-ht3ry9i0	121	36	monensin	monensin	NNP
cord-104223-ht3ry9i0	121	37	-	-	HYPH
cord-104223-ht3ry9i0	121	38	treated	treat	VBN
cord-104223-ht3ry9i0	121	39	cells	cell	NNS
cord-104223-ht3ry9i0	121	40	(	(	-LRB-
cord-104223-ht3ry9i0	121	41	Fig	fig	NN
cord-104223-ht3ry9i0	121	42	.	.	NNP
cord-104223-ht3ry9i0	121	43	2	2	CD
cord-104223-ht3ry9i0	121	44	C	c	NN
cord-104223-ht3ry9i0	121	45	)	)	-RRB-
cord-104223-ht3ry9i0	121	46	(	(	-LRB-
cord-104223-ht3ry9i0	121	47	Yates	Yates	NNP
cord-104223-ht3ry9i0	121	48	and	and	CC
cord-104223-ht3ry9i0	121	49	Berry	Berry	NNP
cord-104223-ht3ry9i0	121	50	,	,	,
cord-104223-ht3ry9i0	121	51	1984	1984	CD
cord-104223-ht3ry9i0	121	52	)	)	-RRB-
cord-104223-ht3ry9i0	121	53	.	.	.
cord-104223-ht3ry9i0	122	1	This	this	DT
cord-104223-ht3ry9i0	122	2	is	be	VBZ
cord-104223-ht3ry9i0	122	3	not	not	RB
cord-104223-ht3ry9i0	122	4	a	a	DT
cord-104223-ht3ry9i0	122	5	peculiar	peculiar	JJ
cord-104223-ht3ry9i0	122	6	effect	effect	NN
cord-104223-ht3ry9i0	122	7	of	of	IN
cord-104223-ht3ry9i0	122	8	monensin	monensin	NNP
cord-104223-ht3ry9i0	122	9	in	in	IN
cord-104223-ht3ry9i0	122	10	Aplysia	Aplysia	NNP
cord-104223-ht3ry9i0	122	11	tissue	tissue	NN
cord-104223-ht3ry9i0	122	12	,	,	,
cord-104223-ht3ry9i0	122	13	as	as	IN
cord-104223-ht3ry9i0	122	14	all	all	DT
cord-104223-ht3ry9i0	122	15	cleavages	cleavage	NNS
cord-104223-ht3ry9i0	122	16	of	of	IN
cord-104223-ht3ry9i0	122	17	the	the	DT
cord-104223-ht3ry9i0	122	18	atrial	atrial	JJ
cord-104223-ht3ry9i0	122	19	gland	gland	NN
cord-104223-ht3ry9i0	122	20	prohormone	prohormone	NN
cord-104223-ht3ry9i0	122	21	are	be	VBP
cord-104223-ht3ry9i0	122	22	blocked	block	VBN
cord-104223-ht3ry9i0	122	23	after	after	IN
cord-104223-ht3ry9i0	122	24	incubation	incubation	NN
cord-104223-ht3ry9i0	122	25	with	with	IN
cord-104223-ht3ry9i0	122	26	monensin	monensin	NNP
cord-104223-ht3ry9i0	122	27	(	(	-LRB-
cord-104223-ht3ry9i0	122	28	Fig	Fig	NNP
cord-104223-ht3ry9i0	122	29	.	.	NNP
cord-104223-ht3ry9i0	122	30	2	2	CD
cord-104223-ht3ry9i0	122	31	C	C	NNP
cord-104223-ht3ry9i0	122	32	)	)	-RRB-
cord-104223-ht3ry9i0	122	33	.	.	.
cord-104223-ht3ry9i0	123	1	Therefore	therefore	RB
cord-104223-ht3ry9i0	123	2	monensin	monensin	NNP
cord-104223-ht3ry9i0	123	3	divides	divide	VBZ
cord-104223-ht3ry9i0	123	4	ELH	ELH	NNP
cord-104223-ht3ry9i0	123	5	processing	processing	NN
cord-104223-ht3ry9i0	123	6	into	into	IN
cord-104223-ht3ry9i0	123	7	two	two	CD
cord-104223-ht3ry9i0	123	8	distinct	distinct	JJ
cord-104223-ht3ry9i0	123	9	steps	step	NNS
cord-104223-ht3ry9i0	123	10	:	:	:
cord-104223-ht3ry9i0	123	11	the	the	DT
cord-104223-ht3ry9i0	123	12	initial	initial	JJ
cord-104223-ht3ry9i0	123	13	cleavage	cleavage	NN
cord-104223-ht3ry9i0	123	14	,	,	,
cord-104223-ht3ry9i0	123	15	which	which	WDT
cord-104223-ht3ry9i0	123	16	occurs	occur	VBZ
cord-104223-ht3ry9i0	123	17	before	before	IN
cord-104223-ht3ry9i0	123	18	the	the	DT
cord-104223-ht3ry9i0	123	19	monensin	monensin	NNP
cord-104223-ht3ry9i0	123	20	block	block	NN
cord-104223-ht3ry9i0	123	21	,	,	,
cord-104223-ht3ry9i0	123	22	and	and	CC
cord-104223-ht3ry9i0	123	23	all	all	DT
cord-104223-ht3ry9i0	123	24	subsequent	subsequent	JJ
cord-104223-ht3ry9i0	123	25	cleavages	cleavage	NNS
cord-104223-ht3ry9i0	123	26	.	.	.
cord-104223-ht3ry9i0	124	1	To	to	TO
cord-104223-ht3ry9i0	124	2	identify	identify	VB
cord-104223-ht3ry9i0	124	3	the	the	DT
cord-104223-ht3ry9i0	124	4	site	site	NN
cord-104223-ht3ry9i0	124	5	of	of	IN
cord-104223-ht3ry9i0	124	6	the	the	DT
cord-104223-ht3ry9i0	124	7	monensin	monensin	NNP
cord-104223-ht3ry9i0	124	8	block	block	NN
cord-104223-ht3ry9i0	124	9	,	,	,
cord-104223-ht3ry9i0	124	10	we	-PRON-	PRP
cord-104223-ht3ry9i0	124	11	examined	examine	VBD
cord-104223-ht3ry9i0	124	12	monensin	monensin	NNP
cord-104223-ht3ry9i0	124	13	-	-	HYPH
cord-104223-ht3ry9i0	124	14	treated	treat	VBN
cord-104223-ht3ry9i0	124	15	bag	bag	NN
cord-104223-ht3ry9i0	124	16	cells	cell	NNS
cord-104223-ht3ry9i0	124	17	in	in	IN
cord-104223-ht3ry9i0	124	18	the	the	DT
cord-104223-ht3ry9i0	124	19	electron	electron	NN
cord-104223-ht3ry9i0	124	20	microscope	microscope	NN
cord-104223-ht3ry9i0	124	21	.	.	.
cord-104223-ht3ry9i0	125	1	As	as	IN
cord-104223-ht3ry9i0	125	2	in	in	IN
cord-104223-ht3ry9i0	125	3	other	other	JJ
cord-104223-ht3ry9i0	125	4	systems	system	NNS
cord-104223-ht3ry9i0	125	5	,	,	,
cord-104223-ht3ry9i0	125	6	monensin	monensin	NNP
cord-104223-ht3ry9i0	125	7	causes	cause	VBZ
cord-104223-ht3ry9i0	125	8	a	a	DT
cord-104223-ht3ry9i0	125	9	specific	specific	JJ
cord-104223-ht3ry9i0	125	10	enlargement	enlargement	NN
cord-104223-ht3ry9i0	125	11	of	of	IN
cord-104223-ht3ry9i0	125	12	Golgi	golgi	NN
cord-104223-ht3ry9i0	125	13	-	-	HYPH
cord-104223-ht3ry9i0	125	14	related	relate	VBN
cord-104223-ht3ry9i0	125	15	compartments	compartment	NNS
cord-104223-ht3ry9i0	125	16	while	while	IN
cord-104223-ht3ry9i0	125	17	leaving	leave	VBG
cord-104223-ht3ry9i0	125	18	other	other	JJ
cord-104223-ht3ry9i0	125	19	cellular	cellular	JJ
cord-104223-ht3ry9i0	125	20	compartments	compartment	NNS
cord-104223-ht3ry9i0	125	21	such	such	JJ
cord-104223-ht3ry9i0	125	22	as	as	IN
cord-104223-ht3ry9i0	125	23	the	the	DT
cord-104223-ht3ry9i0	125	24	nucleus	nucleus	NN
cord-104223-ht3ry9i0	125	25	,	,	,
cord-104223-ht3ry9i0	125	26	ER	ER	NNP
cord-104223-ht3ry9i0	125	27	,	,	,
cord-104223-ht3ry9i0	125	28	mitochondria	mitochondrion	NNS
cord-104223-ht3ry9i0	125	29	,	,	,
cord-104223-ht3ry9i0	125	30	lysosomes	lysosome	NNS
cord-104223-ht3ry9i0	125	31	,	,	,
cord-104223-ht3ry9i0	125	32	and	and	CC
cord-104223-ht3ry9i0	125	33	mature	mature	VB
cord-104223-ht3ry9i0	125	34	DCVs	dcv	NNS
cord-104223-ht3ry9i0	125	35	relatively	relatively	RB
cord-104223-ht3ry9i0	125	36	unchanged	unchanged	JJ
cord-104223-ht3ry9i0	125	37	(	(	-LRB-
cord-104223-ht3ry9i0	125	38	Tartakoff	Tartakoff	NNP
cord-104223-ht3ry9i0	125	39	,	,	,
cord-104223-ht3ry9i0	125	40	1983	1983	CD
cord-104223-ht3ry9i0	125	41	)	)	-RRB-
cord-104223-ht3ry9i0	125	42	.	.	.
cord-104223-ht3ry9i0	126	1	In	in	IN
cord-104223-ht3ry9i0	126	2	the	the	DT
cord-104223-ht3ry9i0	126	3	bag	bag	NN
cord-104223-ht3ry9i0	126	4	cells	cell	NNS
cord-104223-ht3ry9i0	126	5	,	,	,
cord-104223-ht3ry9i0	126	6	some	some	DT
cord-104223-ht3ry9i0	126	7	of	of	IN
cord-104223-ht3ry9i0	126	8	these	these	DT
cord-104223-ht3ry9i0	126	9	vacuoles	vacuole	NNS
cord-104223-ht3ry9i0	126	10	contain	contain	VBP
cord-104223-ht3ry9i0	126	11	dense	dense	JJ
cord-104223-ht3ry9i0	126	12	core	core	NN
cord-104223-ht3ry9i0	126	13	material	material	NN
cord-104223-ht3ry9i0	126	14	,	,	,
cord-104223-ht3ry9i0	126	15	and	and	CC
cord-104223-ht3ry9i0	126	16	these	these	DT
cord-104223-ht3ry9i0	126	17	can	can	MD
cord-104223-ht3ry9i0	126	18	be	be	VB
cord-104223-ht3ry9i0	126	19	divided	divide	VBN
cord-104223-ht3ry9i0	126	20	into	into	IN
cord-104223-ht3ry9i0	126	21	two	two	CD
cord-104223-ht3ry9i0	126	22	general	general	JJ
cord-104223-ht3ry9i0	126	23	types	type	NNS
cord-104223-ht3ry9i0	126	24	:	:	:
cord-104223-ht3ry9i0	126	25	(	(	-LRB-
cord-104223-ht3ry9i0	126	26	a	a	LS
cord-104223-ht3ry9i0	126	27	)	)	-RRB-
cord-104223-ht3ry9i0	126	28	vacuoles	vacuole	NNS
cord-104223-ht3ry9i0	126	29	with	with	IN
cord-104223-ht3ry9i0	126	30	densities	density	NNS
cord-104223-ht3ry9i0	126	31	that	that	WDT
cord-104223-ht3ry9i0	126	32	are	be	VBP
cord-104223-ht3ry9i0	126	33	homogeneous	homogeneous	JJ
cord-104223-ht3ry9i0	126	34	in	in	IN
cord-104223-ht3ry9i0	126	35	appearance	appearance	NN
cord-104223-ht3ry9i0	126	36	(	(	-LRB-
cord-104223-ht3ry9i0	126	37	80	80	CD
cord-104223-ht3ry9i0	126	38	%	%	NN
cord-104223-ht3ry9i0	126	39	)	)	-RRB-
cord-104223-ht3ry9i0	126	40	and	and	CC
cord-104223-ht3ry9i0	126	41	(	(	-LRB-
cord-104223-ht3ry9i0	126	42	b	b	NN
cord-104223-ht3ry9i0	126	43	)	)	-RRB-
cord-104223-ht3ry9i0	126	44	vacuoles	vacuole	NNS
cord-104223-ht3ry9i0	126	45	that	that	WDT
cord-104223-ht3ry9i0	126	46	contain	contain	VBP
cord-104223-ht3ry9i0	126	47	two	two	CD
cord-104223-ht3ry9i0	126	48	different	different	JJ
cord-104223-ht3ry9i0	126	49	types	type	NNS
cord-104223-ht3ry9i0	126	50	of	of	IN
cord-104223-ht3ry9i0	126	51	densities	density	NNS
cord-104223-ht3ry9i0	126	52	(	(	-LRB-
cord-104223-ht3ry9i0	126	53	20	20	CD
cord-104223-ht3ry9i0	126	54	%	%	NN
cord-104223-ht3ry9i0	126	55	;	;	:
cord-104223-ht3ry9i0	126	56	Fig	Fig	NNP
cord-104223-ht3ry9i0	126	57	.	.	.
cord-104223-ht3ry9i0	126	58	3	3	CD
cord-104223-ht3ry9i0	126	59	A	a	NN
cord-104223-ht3ry9i0	126	60	)	)	-RRB-
cord-104223-ht3ry9i0	126	61	.	.	.
cord-104223-ht3ry9i0	127	1	Examination	examination	NN
cord-104223-ht3ry9i0	127	2	of	of	IN
cord-104223-ht3ry9i0	127	3	the	the	DT
cord-104223-ht3ry9i0	127	4	densities	density	NNS
cord-104223-ht3ry9i0	127	5	with	with	IN
cord-104223-ht3ry9i0	127	6	immunoelectron	immunoelectron	NNP
cord-104223-ht3ry9i0	127	7	microscopy	microscopy	NNS
cord-104223-ht3ry9i0	127	8	reveal	reveal	VBP
cord-104223-ht3ry9i0	127	9	thathomogeneous	thathomogeneous	JJ
cord-104223-ht3ry9i0	127	10	dense	dense	JJ
cord-104223-ht3ry9i0	127	11	cores	core	NNS
cord-104223-ht3ry9i0	127	12	contain	contain	VBP
cord-104223-ht3ry9i0	127	13	intermixed	intermix	VBN
cord-104223-ht3ry9i0	127	14	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	127	15	-	-	HYPH
cord-104223-ht3ry9i0	127	16	terminal	terminal	NN
cord-104223-ht3ry9i0	127	17	(	(	-LRB-
cord-104223-ht3ry9i0	127	18	ELH	ELH	NNP
cord-104223-ht3ry9i0	127	19	)	)	-RRB-
cord-104223-ht3ry9i0	127	20	and	and	CC
cord-104223-ht3ry9i0	127	21	amino	amino	NN
cord-104223-ht3ry9i0	127	22	-	-	HYPH
cord-104223-ht3ry9i0	127	23	terminal	terminal	NN
cord-104223-ht3ry9i0	127	24	(	(	-LRB-
cord-104223-ht3ry9i0	127	25	peptide	peptide	NN
cord-104223-ht3ry9i0	127	26	K	K	NNP
cord-104223-ht3ry9i0	127	27	)	)	-RRB-
cord-104223-ht3ry9i0	127	28	immunoreactivity	immunoreactivity	NN
cord-104223-ht3ry9i0	127	29	,	,	,
cord-104223-ht3ry9i0	127	30	but	but	CC
cord-104223-ht3ry9i0	127	31	,	,	,
cord-104223-ht3ry9i0	127	32	as	as	IN
cord-104223-ht3ry9i0	127	33	illustrated	illustrate	VBN
cord-104223-ht3ry9i0	127	34	in	in	IN
cord-104223-ht3ry9i0	127	35	Fig	Fig	NNP
cord-104223-ht3ry9i0	127	36	.	.	.
cord-104223-ht3ry9i0	128	1	3	3	CD
cord-104223-ht3ry9i0	128	2	B	b	NN
cord-104223-ht3ry9i0	128	3	,	,	,
cord-104223-ht3ry9i0	128	4	when	when	WRB
cord-104223-ht3ry9i0	128	5	two	two	CD
cord-104223-ht3ry9i0	128	6	separate	separate	JJ
cord-104223-ht3ry9i0	128	7	densities	density	NNS
cord-104223-ht3ry9i0	128	8	1	1	CD
cord-104223-ht3ry9i0	128	9	-	-	SYM
cord-104223-ht3ry9i0	128	10	4	4	CD
cord-104223-ht3ry9i0	128	11	)	)	-RRB-
cord-104223-ht3ry9i0	128	12	.	.	.
cord-104223-ht3ry9i0	129	1	The	the	DT
cord-104223-ht3ry9i0	129	2	clusters	cluster	NNS
cord-104223-ht3ry9i0	129	3	were	be	VBD
cord-104223-ht3ry9i0	129	4	then	then	RB
cord-104223-ht3ry9i0	129	5	extracted	extract	VBN
cord-104223-ht3ry9i0	129	6	with	with	IN
cord-104223-ht3ry9i0	129	7	acid	acid	NN
cord-104223-ht3ry9i0	129	8	acetone	acetone	NN
cord-104223-ht3ry9i0	129	9	and	and	CC
cord-104223-ht3ry9i0	129	10	fractionated	fractionate	VBN
cord-104223-ht3ry9i0	129	11	on	on	IN
cord-104223-ht3ry9i0	129	12	SDS	sds	NN
cord-104223-ht3ry9i0	129	13	-	-	HYPH
cord-104223-ht3ry9i0	129	14	urea	urea	NN
cord-104223-ht3ry9i0	129	15	gels	gel	NNS
cord-104223-ht3ry9i0	129	16	.	.	.
cord-104223-ht3ry9i0	130	1	(	(	-LRB-
cord-104223-ht3ry9i0	130	2	Neweomb	Neweomb	NNP
cord-104223-ht3ry9i0	130	3	et	et	NNP
cord-104223-ht3ry9i0	130	4	al	al	NNP
cord-104223-ht3ry9i0	130	5	.	.	NNP
cord-104223-ht3ry9i0	130	6	,	,	,
cord-104223-ht3ry9i0	130	7	1988	1988	CD
cord-104223-ht3ry9i0	130	8	)	)	-RRB-
cord-104223-ht3ry9i0	130	9	.	.	.
cord-104223-ht3ry9i0	131	1	The	the	DT
cord-104223-ht3ry9i0	131	2	bands	band	NNS
cord-104223-ht3ry9i0	131	3	are	be	VBP
cord-104223-ht3ry9i0	131	4	marked	mark	VBN
cord-104223-ht3ry9i0	131	5	according	accord	VBG
cord-104223-ht3ry9i0	131	6	to	to	IN
cord-104223-ht3ry9i0	131	7	the	the	DT
cord-104223-ht3ry9i0	131	8	nomenclature	nomenclature	NN
cord-104223-ht3ry9i0	131	9	outlined	outline	VBN
cord-104223-ht3ry9i0	131	10	in	in	IN
cord-104223-ht3ry9i0	131	11	Fig	Fig	NNP
cord-104223-ht3ry9i0	131	12	.	.	.
cord-104223-ht3ry9i0	132	1	1	1	LS
cord-104223-ht3ry9i0	132	2	.	.	.
cord-104223-ht3ry9i0	133	1	The	the	DT
cord-104223-ht3ry9i0	133	2	initial	initial	JJ
cord-104223-ht3ry9i0	133	3	cleavage	cleavage	NN
cord-104223-ht3ry9i0	133	4	is	be	VBZ
cord-104223-ht3ry9i0	133	5	occurring	occur	VBG
cord-104223-ht3ry9i0	133	6	at	at	IN
cord-104223-ht3ry9i0	133	7	the	the	DT
cord-104223-ht3ry9i0	133	8	30-min	30-min	CD
cord-104223-ht3ry9i0	133	9	chase	chase	NN
cord-104223-ht3ry9i0	133	10	and	and	CC
cord-104223-ht3ry9i0	133	11	is	be	VBZ
cord-104223-ht3ry9i0	133	12	complete	complete	JJ
cord-104223-ht3ry9i0	133	13	after	after	IN
cord-104223-ht3ry9i0	133	14	2	2	CD
cord-104223-ht3ry9i0	133	15	h.	h.	NN
cord-104223-ht3ry9i0	133	16	(	(	-LRB-
cord-104223-ht3ry9i0	133	17	C	C	NNP
cord-104223-ht3ry9i0	133	18	)	)	-RRB-
cord-104223-ht3ry9i0	134	1	After	after	IN
cord-104223-ht3ry9i0	134	2	pretreatment	pretreatment	NN
cord-104223-ht3ry9i0	134	3	for	for	IN
cord-104223-ht3ry9i0	134	4	2	2	CD
cord-104223-ht3ry9i0	134	5	h	h	NN
cord-104223-ht3ry9i0	134	6	with	with	IN
cord-104223-ht3ry9i0	134	7	10/~M	10/~m	CD
cord-104223-ht3ry9i0	134	8	monensin	monensin	NNP
cord-104223-ht3ry9i0	134	9	plus	plus	CC
cord-104223-ht3ry9i0	134	10	1	1	CD
cord-104223-ht3ry9i0	134	11	%	%	NN
cord-104223-ht3ry9i0	134	12	EtOH	EtOH	NNP
cord-104223-ht3ry9i0	134	13	(	(	-LRB-
cord-104223-ht3ry9i0	134	14	lanes	lane	NNS
cord-104223-ht3ry9i0	134	15	2	2	CD
cord-104223-ht3ry9i0	134	16	and	and	CC
cord-104223-ht3ry9i0	134	17	4	4	CD
cord-104223-ht3ry9i0	134	18	)	)	-RRB-
cord-104223-ht3ry9i0	134	19	or	or	CC
cord-104223-ht3ry9i0	134	20	ASW	ASW	NNP
cord-104223-ht3ry9i0	134	21	plus	plus	CC
cord-104223-ht3ry9i0	134	22	1	1	CD
cord-104223-ht3ry9i0	134	23	%	%	NN
cord-104223-ht3ry9i0	134	24	EtOH	EtOH	NNP
cord-104223-ht3ry9i0	134	25	(	(	-LRB-
cord-104223-ht3ry9i0	134	26	lanes	lane	NNS
cord-104223-ht3ry9i0	134	27	1	1	CD
cord-104223-ht3ry9i0	134	28	and	and	CC
cord-104223-ht3ry9i0	134	29	3	3	CD
cord-104223-ht3ry9i0	134	30	)	)	-RRB-
cord-104223-ht3ry9i0	134	31	,	,	,
cord-104223-ht3ry9i0	134	32	bag	bag	NN
cord-104223-ht3ry9i0	134	33	cell	cell	NN
cord-104223-ht3ry9i0	134	34	clusters	cluster	NNS
cord-104223-ht3ry9i0	134	35	(	(	-LRB-
cord-104223-ht3ry9i0	134	36	lanes	lane	NNS
cord-104223-ht3ry9i0	134	37	I	-PRON-	PRP
cord-104223-ht3ry9i0	134	38	and	and	CC
cord-104223-ht3ry9i0	134	39	2	2	CD
cord-104223-ht3ry9i0	134	40	)	)	-RRB-
cord-104223-ht3ry9i0	134	41	or	or	CC
cord-104223-ht3ry9i0	134	42	atrial	atrial	JJ
cord-104223-ht3ry9i0	134	43	gland	gland	NN
cord-104223-ht3ry9i0	134	44	fragments	fragment	NNS
cord-104223-ht3ry9i0	134	45	(	(	-LRB-
cord-104223-ht3ry9i0	134	46	1	1	CD
cord-104223-ht3ry9i0	134	47	mm	mm	NN
cord-104223-ht3ry9i0	134	48	x	x	SYM
cord-104223-ht3ry9i0	134	49	1	1	CD
cord-104223-ht3ry9i0	134	50	mm	mm	NN
cord-104223-ht3ry9i0	134	51	;	;	:
cord-104223-ht3ry9i0	134	52	lanes	lane	NNS
cord-104223-ht3ry9i0	134	53	3	3	CD
cord-104223-ht3ry9i0	134	54	and	and	CC
cord-104223-ht3ry9i0	134	55	4	4	CD
cord-104223-ht3ry9i0	134	56	)	)	-RRB-
cord-104223-ht3ry9i0	134	57	were	be	VBD
cord-104223-ht3ry9i0	134	58	pulsed	pulse	VBN
cord-104223-ht3ry9i0	134	59	for	for	IN
cord-104223-ht3ry9i0	134	60	2	2	CD
cord-104223-ht3ry9i0	134	61	h	h	NN
cord-104223-ht3ry9i0	134	62	with	with	IN
cord-104223-ht3ry9i0	134	63	[	[	-LRB-
cord-104223-ht3ry9i0	134	64	3H]leucine	3h]leucine	CD
cord-104223-ht3ry9i0	134	65	and	and	CC
cord-104223-ht3ry9i0	134	66	chased	chase	VBD
cord-104223-ht3ry9i0	134	67	for	for	IN
cord-104223-ht3ry9i0	134	68	4	4	CD
cord-104223-ht3ry9i0	134	69	h	h	NN
cord-104223-ht3ry9i0	134	70	(	(	-LRB-
cord-104223-ht3ry9i0	134	71	bag	bag	NN
cord-104223-ht3ry9i0	134	72	cells	cell	NNS
cord-104223-ht3ry9i0	134	73	)	)	-RRB-
cord-104223-ht3ry9i0	134	74	or	or	CC
cord-104223-ht3ry9i0	134	75	20	20	CD
cord-104223-ht3ry9i0	134	76	h	h	NN
cord-104223-ht3ry9i0	134	77	(	(	-LRB-
cord-104223-ht3ry9i0	134	78	atri	atri	NNP
cord-104223-ht3ry9i0	134	79	.al	.al	CD
cord-104223-ht3ry9i0	134	80	glands	gland	NNS
cord-104223-ht3ry9i0	134	81	)	)	-RRB-
cord-104223-ht3ry9i0	134	82	before	before	IN
cord-104223-ht3ry9i0	134	83	acid	acid	NN
cord-104223-ht3ry9i0	134	84	acetone	acetone	NN
cord-104223-ht3ry9i0	134	85	extraction	extraction	NN
cord-104223-ht3ry9i0	134	86	.	.	.
cord-104223-ht3ry9i0	135	1	Under	under	IN
cord-104223-ht3ry9i0	135	2	these	these	DT
cord-104223-ht3ry9i0	135	3	conditions	condition	NNS
cord-104223-ht3ry9i0	135	4	,	,	,
cord-104223-ht3ry9i0	135	5	the	the	DT
cord-104223-ht3ry9i0	135	6	initial	initial	JJ
cord-104223-ht3ry9i0	135	7	cleavage	cleavage	NN
cord-104223-ht3ry9i0	135	8	of	of	IN
cord-104223-ht3ry9i0	135	9	the	the	DT
cord-104223-ht3ry9i0	135	10	bag	bag	NN
cord-104223-ht3ry9i0	135	11	cell	cell	NN
cord-104223-ht3ry9i0	135	12	prohormone	prohormone	NN
cord-104223-ht3ry9i0	135	13	is	be	VBZ
cord-104223-ht3ry9i0	135	14	completed	complete	VBN
cord-104223-ht3ry9i0	135	15	in	in	IN
cord-104223-ht3ry9i0	135	16	monensin	monensin	NNP
cord-104223-ht3ry9i0	135	17	,	,	,
cord-104223-ht3ry9i0	135	18	but	but	CC
cord-104223-ht3ry9i0	135	19	all	all	DT
cord-104223-ht3ry9i0	135	20	further	further	JJ
cord-104223-ht3ry9i0	135	21	cleavages	cleavage	NNS
cord-104223-ht3ry9i0	135	22	of	of	IN
cord-104223-ht3ry9i0	135	23	the	the	DT
cord-104223-ht3ry9i0	135	24	intermediates	intermediate	NNS
cord-104223-ht3ry9i0	135	25	are	be	VBP
cord-104223-ht3ry9i0	135	26	blocked	block	VBN
cord-104223-ht3ry9i0	135	27	(	(	-LRB-
cord-104223-ht3ry9i0	135	28	lane	lane	NN
cord-104223-ht3ry9i0	135	29	2	2	CD
cord-104223-ht3ry9i0	135	30	)	)	-RRB-
cord-104223-ht3ry9i0	135	31	.	.	.
cord-104223-ht3ry9i0	136	1	In	in	IN
cord-104223-ht3ry9i0	136	2	contrast	contrast	NN
cord-104223-ht3ry9i0	136	3	,	,	,
cord-104223-ht3ry9i0	136	4	the	the	DT
cord-104223-ht3ry9i0	136	5	atrial	atrial	JJ
cord-104223-ht3ry9i0	136	6	gland	gland	NN
cord-104223-ht3ry9i0	136	7	precursor	precursor	NN
cord-104223-ht3ry9i0	136	8	accumulates	accumulate	VBZ
cord-104223-ht3ry9i0	136	9	in	in	IN
cord-104223-ht3ry9i0	136	10	monensintreated	monensintreated	JJ
cord-104223-ht3ry9i0	136	11	cells	cell	NNS
cord-104223-ht3ry9i0	136	12	(	(	-LRB-
cord-104223-ht3ry9i0	136	13	lane	lane	NN
cord-104223-ht3ry9i0	136	14	4	4	CD
cord-104223-ht3ry9i0	136	15	)	)	-RRB-
cord-104223-ht3ry9i0	136	16	.	.	.
cord-104223-ht3ry9i0	137	1	Other	other	JJ
cord-104223-ht3ry9i0	137	2	bag	bag	NN
cord-104223-ht3ry9i0	137	3	cell	cell	NN
cord-104223-ht3ry9i0	137	4	clusters	cluster	NNS
cord-104223-ht3ry9i0	137	5	labeled	label	VBN
cord-104223-ht3ry9i0	137	6	with	with	IN
cord-104223-ht3ry9i0	137	7	[	[	-LRB-
cord-104223-ht3ry9i0	137	8	3H]leucine	3H]leucine	NNP
cord-104223-ht3ry9i0	137	9	were	be	VBD
cord-104223-ht3ry9i0	137	10	assessed	assess	VBN
cord-104223-ht3ry9i0	137	11	by	by	IN
cord-104223-ht3ry9i0	137	12	HPLC	HPLC	NNP
cord-104223-ht3ry9i0	137	13	analysis	analysis	NN
cord-104223-ht3ry9i0	137	14	(	(	-LRB-
cord-104223-ht3ry9i0	137	15	Newcomb	Newcomb	NNP
cord-104223-ht3ry9i0	137	16	and	and	CC
cord-104223-ht3ry9i0	137	17	Scheller	Scheller	NNP
cord-104223-ht3ry9i0	137	18	,	,	,
cord-104223-ht3ry9i0	137	19	1987	1987	CD
cord-104223-ht3ry9i0	137	20	)	)	-RRB-
cord-104223-ht3ry9i0	137	21	,	,	,
cord-104223-ht3ry9i0	137	22	and	and	CC
cord-104223-ht3ry9i0	137	23	all	all	DT
cord-104223-ht3ry9i0	137	24	radioactivity	radioactivity	NN
cord-104223-ht3ry9i0	137	25	was	be	VBD
cord-104223-ht3ry9i0	137	26	found	find	VBN
cord-104223-ht3ry9i0	137	27	in	in	IN
cord-104223-ht3ry9i0	137	28	the	the	DT
cord-104223-ht3ry9i0	137	29	first	first	JJ
cord-104223-ht3ry9i0	137	30	intermediates	intermediate	NNS
cord-104223-ht3ry9i0	137	31	,	,	,
cord-104223-ht3ry9i0	137	32	demonstrating	demonstrate	VBG
cord-104223-ht3ry9i0	137	33	more	more	RBR
cord-104223-ht3ry9i0	137	34	conclusively	conclusively	RB
cord-104223-ht3ry9i0	137	35	that	that	IN
cord-104223-ht3ry9i0	137	36	no	no	DT
cord-104223-ht3ry9i0	137	37	further	further	JJ
cord-104223-ht3ry9i0	137	38	cleavages	cleavage	NNS
cord-104223-ht3ry9i0	137	39	of	of	IN
cord-104223-ht3ry9i0	137	40	the	the	DT
cord-104223-ht3ry9i0	137	41	F2	f2	NN
cord-104223-ht3ry9i0	137	42	or	or	CC
cord-104223-ht3ry9i0	137	43	13	13	CD
cord-104223-ht3ry9i0	137	44	intermediate	intermediate	JJ
cord-104223-ht3ry9i0	137	45	occur	occur	VBP
cord-104223-ht3ry9i0	137	46	in	in	IN
cord-104223-ht3ry9i0	137	47	the	the	DT
cord-104223-ht3ry9i0	137	48	monensin	monensin	NNP
cord-104223-ht3ry9i0	137	49	experiment	experiment	NN
cord-104223-ht3ry9i0	137	50	(	(	-LRB-
cord-104223-ht3ry9i0	137	51	data	datum	NNS
cord-104223-ht3ry9i0	137	52	not	not	RB
cord-104223-ht3ry9i0	137	53	shown	show	VBN
cord-104223-ht3ry9i0	137	54	)	)	-RRB-
cord-104223-ht3ry9i0	137	55	.	.	.
cord-104223-ht3ry9i0	138	1	are	be	VBP
cord-104223-ht3ry9i0	138	2	observed	observe	VBN
cord-104223-ht3ry9i0	138	3	the	the	DT
cord-104223-ht3ry9i0	138	4	immunoreactivity	immunoreactivity	NN
cord-104223-ht3ry9i0	138	5	of	of	IN
cord-104223-ht3ry9i0	138	6	the	the	DT
cord-104223-ht3ry9i0	138	7	different	different	JJ
cord-104223-ht3ry9i0	138	8	dense	dense	JJ
cord-104223-ht3ry9i0	138	9	cores	core	NNS
cord-104223-ht3ry9i0	138	10	is	be	VBZ
cord-104223-ht3ry9i0	138	11	segregated	segregate	VBN
cord-104223-ht3ry9i0	138	12	.	.	.
cord-104223-ht3ry9i0	139	1	To	to	TO
cord-104223-ht3ry9i0	139	2	demonstrate	demonstrate	VB
cord-104223-ht3ry9i0	139	3	that	that	IN
cord-104223-ht3ry9i0	139	4	these	these	DT
cord-104223-ht3ry9i0	139	5	densities	density	NNS
cord-104223-ht3ry9i0	139	6	actually	actually	RB
cord-104223-ht3ry9i0	139	7	represent	represent	VBP
cord-104223-ht3ry9i0	139	8	the	the	DT
cord-104223-ht3ry9i0	139	9	site	site	NN
cord-104223-ht3ry9i0	139	10	of	of	IN
cord-104223-ht3ry9i0	139	11	blockage	blockage	NN
cord-104223-ht3ry9i0	139	12	,	,	,
cord-104223-ht3ry9i0	139	13	the	the	DT
cord-104223-ht3ry9i0	139	14	monensin	monensin	NNP
cord-104223-ht3ry9i0	139	15	-	-	HYPH
cord-104223-ht3ry9i0	139	16	treated	treat	VBN
cord-104223-ht3ry9i0	139	17	bag	bag	NN
cord-104223-ht3ry9i0	139	18	cells	cell	NNS
cord-104223-ht3ry9i0	139	19	were	be	VBD
cord-104223-ht3ry9i0	139	20	pulse	pulse	NN
cord-104223-ht3ry9i0	139	21	chased	chase	VBN
cord-104223-ht3ry9i0	139	22	with	with	IN
cord-104223-ht3ry9i0	139	23	either	either	DT
cord-104223-ht3ry9i0	139	24	[	[	-LRB-
cord-104223-ht3ry9i0	139	25	3H]Leu	3h]leu	CD
cord-104223-ht3ry9i0	139	26	,	,	,
cord-104223-ht3ry9i0	139	27	[	[	-LRB-
cord-104223-ht3ry9i0	139	28	3H]Phe	3h]phe	CD
cord-104223-ht3ry9i0	139	29	,	,	,
cord-104223-ht3ry9i0	139	30	or	or	CC
cord-104223-ht3ry9i0	139	31	[	[	-LRB-
cord-104223-ht3ry9i0	139	32	3H]Ile	3h]ile	CD
cord-104223-ht3ry9i0	139	33	and	and	CC
cord-104223-ht3ry9i0	139	34	processed	process	VBN
cord-104223-ht3ry9i0	139	35	for	for	IN
cord-104223-ht3ry9i0	139	36	EM	EM	NNP
cord-104223-ht3ry9i0	139	37	autoradiography	autoradiography	NNP
cord-104223-ht3ry9i0	139	38	.	.	.
cord-104223-ht3ry9i0	140	1	As	as	IN
cord-104223-ht3ry9i0	140	2	evident	evident	JJ
cord-104223-ht3ry9i0	140	3	in	in	IN
cord-104223-ht3ry9i0	140	4	Fig	Fig	NNP
cord-104223-ht3ry9i0	140	5	.	.	.
cord-104223-ht3ry9i0	141	1	3	3	LS
cord-104223-ht3ry9i0	142	1	Monensin	Monensin	NNP
cord-104223-ht3ry9i0	142	2	blocks	block	VBZ
cord-104223-ht3ry9i0	142	3	transport	transport	NN
cord-104223-ht3ry9i0	142	4	at	at	IN
cord-104223-ht3ry9i0	142	5	various	various	JJ
cord-104223-ht3ry9i0	142	6	sites	site	NNS
cord-104223-ht3ry9i0	142	7	in	in	IN
cord-104223-ht3ry9i0	142	8	different	different	JJ
cord-104223-ht3ry9i0	142	9	systems	system	NNS
cord-104223-ht3ry9i0	142	10	but	but	CC
cord-104223-ht3ry9i0	142	11	almost	almost	RB
cord-104223-ht3ry9i0	142	12	always	always	RB
cord-104223-ht3ry9i0	142	13	blocks	block	VBZ
cord-104223-ht3ry9i0	142	14	transport	transport	NN
cord-104223-ht3ry9i0	142	15	somewhere	somewhere	RB
cord-104223-ht3ry9i0	142	16	within	within	IN
cord-104223-ht3ry9i0	142	17	the	the	DT
cord-104223-ht3ry9i0	142	18	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	142	19	apparatus	apparatus	NN
cord-104223-ht3ry9i0	143	1	(	(	-LRB-
cord-104223-ht3ry9i0	143	2	Gritliths	Gritliths	NNP
cord-104223-ht3ry9i0	143	3	et	et	NNP
cord-104223-ht3ry9i0	143	4	al	al	NNP
cord-104223-ht3ry9i0	143	5	.	.	NNP
cord-104223-ht3ry9i0	143	6	,	,	,
cord-104223-ht3ry9i0	143	7	1983	1983	CD
cord-104223-ht3ry9i0	143	8	;	;	:
cord-104223-ht3ry9i0	143	9	Johnson	Johnson	NNP
cord-104223-ht3ry9i0	143	10	and	and	CC
cord-104223-ht3ry9i0	143	11	Schlessinger	Schlessinger	NNP
cord-104223-ht3ry9i0	143	12	,	,	,
cord-104223-ht3ry9i0	143	13	1980	1980	CD
cord-104223-ht3ry9i0	143	14	;	;	:
cord-104223-ht3ry9i0	143	15	Orci	Orci	NNP
cord-104223-ht3ry9i0	143	16	et	et	NNP
cord-104223-ht3ry9i0	143	17	al	al	NNP
cord-104223-ht3ry9i0	143	18	.	.	NNP
cord-104223-ht3ry9i0	143	19	,	,	,
cord-104223-ht3ry9i0	143	20	1984	1984	CD
cord-104223-ht3ry9i0	143	21	)	)	-RRB-
cord-104223-ht3ry9i0	143	22	.	.	.
cord-104223-ht3ry9i0	144	1	Osmium	osmium	NN
cord-104223-ht3ry9i0	144	2	,	,	,
cord-104223-ht3ry9i0	144	3	a	a	DT
cord-104223-ht3ry9i0	144	4	specific	specific	JJ
cord-104223-ht3ry9i0	144	5	marker	marker	NN
cord-104223-ht3ry9i0	144	6	for	for	IN
cord-104223-ht3ry9i0	144	7	the	the	DT
cord-104223-ht3ry9i0	144	8	cis	cis	NNP
cord-104223-ht3ry9i0	144	9	-	-	HYPH
cord-104223-ht3ry9i0	144	10	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	144	11	compartment	compartment	NN
cord-104223-ht3ry9i0	144	12	(	(	-LRB-
cord-104223-ht3ry9i0	144	13	Friend	friend	NN
cord-104223-ht3ry9i0	144	14	and	and	CC
cord-104223-ht3ry9i0	144	15	Murray	Murray	NNP
cord-104223-ht3ry9i0	144	16	,	,	,
cord-104223-ht3ry9i0	144	17	1965	1965	CD
cord-104223-ht3ry9i0	144	18	)	)	-RRB-
cord-104223-ht3ry9i0	144	19	,	,	,
cord-104223-ht3ry9i0	144	20	labels	label	VBZ
cord-104223-ht3ry9i0	144	21	a	a	DT
cord-104223-ht3ry9i0	144	22	subset	subset	NN
cord-104223-ht3ry9i0	144	23	of	of	IN
cord-104223-ht3ry9i0	144	24	vacuoles	vacuole	NNS
cord-104223-ht3ry9i0	144	25	but	but	CC
cord-104223-ht3ry9i0	144	26	does	do	VBZ
cord-104223-ht3ry9i0	144	27	not	not	RB
cord-104223-ht3ry9i0	144	28	label	label	VB
cord-104223-ht3ry9i0	144	29	vacuoles	vacuole	NNS
cord-104223-ht3ry9i0	144	30	that	that	WDT
cord-104223-ht3ry9i0	144	31	contain	contain	VBP
cord-104223-ht3ry9i0	144	32	densities	density	NNS
cord-104223-ht3ry9i0	144	33	(	(	-LRB-
cord-104223-ht3ry9i0	144	34	data	datum	NNS
cord-104223-ht3ry9i0	144	35	not	not	RB
cord-104223-ht3ry9i0	144	36	shown	show	VBN
cord-104223-ht3ry9i0	144	37	)	)	-RRB-
cord-104223-ht3ry9i0	144	38	,	,	,
cord-104223-ht3ry9i0	144	39	suggesting	suggest	VBG
cord-104223-ht3ry9i0	144	40	the	the	DT
cord-104223-ht3ry9i0	144	41	monensin	monensin	JJ
cord-104223-ht3ry9i0	144	42	block	block	NN
cord-104223-ht3ry9i0	144	43	is	be	VBZ
cord-104223-ht3ry9i0	144	44	beyond	beyond	IN
cord-104223-ht3ry9i0	144	45	this	this	DT
cord-104223-ht3ry9i0	144	46	point	point	NN
cord-104223-ht3ry9i0	144	47	in	in	IN
cord-104223-ht3ry9i0	144	48	the	the	DT
cord-104223-ht3ry9i0	144	49	secretory	secretory	JJ
cord-104223-ht3ry9i0	144	50	pathway	pathway	NN
cord-104223-ht3ry9i0	144	51	.	.	.
cord-104223-ht3ry9i0	145	1	The	the	DT
cord-104223-ht3ry9i0	145	2	presence	presence	NN
cord-104223-ht3ry9i0	145	3	of	of	IN
cord-104223-ht3ry9i0	145	4	sorted	sort	VBN
cord-104223-ht3ry9i0	145	5	densities	density	NNS
cord-104223-ht3ry9i0	145	6	suggests	suggest	VBZ
cord-104223-ht3ry9i0	145	7	that	that	IN
cord-104223-ht3ry9i0	145	8	segregation	segregation	NN
cord-104223-ht3ry9i0	145	9	occurs	occur	VBZ
cord-104223-ht3ry9i0	145	10	at	at	IN
cord-104223-ht3ry9i0	145	11	this	this	DT
cord-104223-ht3ry9i0	145	12	stage	stage	NN
cord-104223-ht3ry9i0	145	13	of	of	IN
cord-104223-ht3ry9i0	145	14	prohormone	prohormone	NN
cord-104223-ht3ry9i0	145	15	processing	processing	NN
cord-104223-ht3ry9i0	145	16	and	and	CC
cord-104223-ht3ry9i0	145	17	that	that	IN
cord-104223-ht3ry9i0	145	18	the	the	DT
cord-104223-ht3ry9i0	145	19	intermediates	intermediate	NNS
cord-104223-ht3ry9i0	145	20	may	may	MD
cord-104223-ht3ry9i0	145	21	have	have	VB
cord-104223-ht3ry9i0	145	22	intrinsic	intrinsic	JJ
cord-104223-ht3ry9i0	145	23	abilities	ability	NNS
cord-104223-ht3ry9i0	145	24	to	to	TO
cord-104223-ht3ry9i0	145	25	aggregate	aggregate	VB
cord-104223-ht3ry9i0	145	26	selectively	selectively	RB
cord-104223-ht3ry9i0	145	27	.	.	.
cord-104223-ht3ry9i0	146	1	These	these	DT
cord-104223-ht3ry9i0	146	2	results	result	NNS
cord-104223-ht3ry9i0	146	3	must	must	MD
cord-104223-ht3ry9i0	146	4	be	be	VB
cord-104223-ht3ry9i0	146	5	interpreted	interpret	VBN
cord-104223-ht3ry9i0	146	6	cautiously	cautiously	RB
cord-104223-ht3ry9i0	146	7	as	as	IN
cord-104223-ht3ry9i0	146	8	the	the	DT
cord-104223-ht3ry9i0	146	9	disruption	disruption	NN
cord-104223-ht3ry9i0	146	10	of	of	IN
cord-104223-ht3ry9i0	146	11	ionic	ionic	NN
cord-104223-ht3ry9i0	146	12	and	and	CC
cord-104223-ht3ry9i0	146	13	pH	pH	NNP
cord-104223-ht3ry9i0	146	14	gradients	gradient	NNS
cord-104223-ht3ry9i0	146	15	in	in	IN
cord-104223-ht3ry9i0	146	16	monensin	monensin	NNP
cord-104223-ht3ry9i0	146	17	-	-	HYPH
cord-104223-ht3ry9i0	146	18	treated	treat	VBN
cord-104223-ht3ry9i0	146	19	cells	cell	NNS
cord-104223-ht3ry9i0	146	20	may	may	MD
cord-104223-ht3ry9i0	146	21	cause	cause	VB
cord-104223-ht3ry9i0	146	22	perturbations	perturbation	NNS
cord-104223-ht3ry9i0	146	23	in	in	IN
cord-104223-ht3ry9i0	146	24	the	the	DT
cord-104223-ht3ry9i0	146	25	sorting	sorting	NN
cord-104223-ht3ry9i0	146	26	process	process	NN
cord-104223-ht3ry9i0	146	27	.	.	.
cord-104223-ht3ry9i0	147	1	In	in	IN
cord-104223-ht3ry9i0	147	2	pulse	pulse	NN
cord-104223-ht3ry9i0	147	3	-	-	HYPH
cord-104223-ht3ry9i0	147	4	chase	chase	NN
cord-104223-ht3ry9i0	147	5	studies	study	NNS
cord-104223-ht3ry9i0	147	6	using	use	VBG
cord-104223-ht3ry9i0	147	7	either	either	CC
cord-104223-ht3ry9i0	147	8	pH]Ile	pH]Ile	NNS
cord-104223-ht3ry9i0	147	9	(	(	-LRB-
cord-104223-ht3ry9i0	147	10	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	147	11	-	-	HYPH
cord-104223-ht3ry9i0	147	12	terminal	terminal	NN
cord-104223-ht3ry9i0	147	13	)	)	-RRB-
cord-104223-ht3ry9i0	147	14	or	or	CC
cord-104223-ht3ry9i0	147	15	[	[	-LRB-
cord-104223-ht3ry9i0	147	16	3H]Phe	3h]phe	CD
cord-104223-ht3ry9i0	147	17	(	(	-LRB-
cord-104223-ht3ry9i0	147	18	amino	amino	NN
cord-104223-ht3ry9i0	147	19	-	-	HYPH
cord-104223-ht3ry9i0	147	20	terminal	terminal	NN
cord-104223-ht3ry9i0	147	21	)	)	-RRB-
cord-104223-ht3ry9i0	147	22	,	,	,
cord-104223-ht3ry9i0	147	23	counts	count	VBZ
cord-104223-ht3ry9i0	147	24	flow	flow	NN
cord-104223-ht3ry9i0	147	25	through	through	IN
cord-104223-ht3ry9i0	147	26	the	the	DT
cord-104223-ht3ry9i0	147	27	secretory	secretory	JJ
cord-104223-ht3ry9i0	147	28	pathway	pathway	NN
cord-104223-ht3ry9i0	147	29	from	from	IN
cord-104223-ht3ry9i0	147	30	ER	ER	NNP
cord-104223-ht3ry9i0	147	31	to	to	IN
cord-104223-ht3ry9i0	147	32	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	147	33	apparatus	apparatus	NN
cord-104223-ht3ry9i0	147	34	to	to	IN
cord-104223-ht3ry9i0	147	35	granules	granule	NNS
cord-104223-ht3ry9i0	147	36	(	(	-LRB-
cord-104223-ht3ry9i0	147	37	Table	table	NN
cord-104223-ht3ry9i0	147	38	I	i	CD
cord-104223-ht3ry9i0	147	39	)	)	-RRB-
cord-104223-ht3ry9i0	147	40	.	.	.
cord-104223-ht3ry9i0	148	1	After	after	IN
cord-104223-ht3ry9i0	148	2	a	a	DT
cord-104223-ht3ry9i0	148	3	30-min	30-min	CD
cord-104223-ht3ry9i0	148	4	pulse	pulse	NN
cord-104223-ht3ry9i0	148	5	with	with	IN
cord-104223-ht3ry9i0	148	6	PHllle	PHllle	NNP
cord-104223-ht3ry9i0	148	7	,	,	,
cord-104223-ht3ry9i0	148	8	a	a	DT
cord-104223-ht3ry9i0	148	9	large	large	JJ
cord-104223-ht3ry9i0	148	10	number	number	NN
cord-104223-ht3ry9i0	148	11	of	of	IN
cord-104223-ht3ry9i0	148	12	grains	grain	NNS
cord-104223-ht3ry9i0	148	13	are	be	VBP
cord-104223-ht3ry9i0	148	14	seen	see	VBN
cord-104223-ht3ry9i0	148	15	over	over	IN
cord-104223-ht3ry9i0	148	16	the	the	DT
cord-104223-ht3ry9i0	148	17	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	148	18	apparatus	apparatus	NN
cord-104223-ht3ry9i0	148	19	(	(	-LRB-
cord-104223-ht3ry9i0	148	20	Fig	Fig	NNP
cord-104223-ht3ry9i0	148	21	.	.	.
cord-104223-ht3ry9i0	148	22	4	4	CD
cord-104223-ht3ry9i0	148	23	A	a	NN
cord-104223-ht3ry9i0	148	24	and	and	CC
cord-104223-ht3ry9i0	148	25	Table	Table	NNP
cord-104223-ht3ry9i0	148	26	I	i	CD
cord-104223-ht3ry9i0	148	27	)	)	-RRB-
cord-104223-ht3ry9i0	148	28	.	.	.
cord-104223-ht3ry9i0	149	1	Since	since	IN
cord-104223-ht3ry9i0	149	2	at	at	IN
cord-104223-ht3ry9i0	149	3	this	this	DT
cord-104223-ht3ry9i0	149	4	time	time	NN
cord-104223-ht3ry9i0	149	5	point	point	NN
cord-104223-ht3ry9i0	149	6	no	no	DT
cord-104223-ht3ry9i0	149	7	processing	processing	NN
cord-104223-ht3ry9i0	149	8	has	have	VBZ
cord-104223-ht3ry9i0	149	9	occurred	occur	VBN
cord-104223-ht3ry9i0	149	10	(	(	-LRB-
cord-104223-ht3ry9i0	149	11	Fig	fig	NN
cord-104223-ht3ry9i0	149	12	.	.	.
cord-104223-ht3ry9i0	149	13	2	2	CD
cord-104223-ht3ry9i0	149	14	B	b	NN
cord-104223-ht3ry9i0	149	15	)	)	-RRB-
cord-104223-ht3ry9i0	149	16	,	,	,
cord-104223-ht3ry9i0	149	17	one	one	PRP
cord-104223-ht3ry9i0	149	18	can	can	MD
cord-104223-ht3ry9i0	149	19	conclude	conclude	VB
cord-104223-ht3ry9i0	149	20	that	that	IN
cord-104223-ht3ry9i0	149	21	cleavage	cleavage	NN
cord-104223-ht3ry9i0	149	22	does	do	VBZ
cord-104223-ht3ry9i0	149	23	not	not	RB
cord-104223-ht3ry9i0	149	24	occur	occur	VB
cord-104223-ht3ry9i0	149	25	early	early	RB
cord-104223-ht3ry9i0	149	26	in	in	IN
cord-104223-ht3ry9i0	149	27	the	the	DT
cord-104223-ht3ry9i0	149	28	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	149	29	apparatus	apparatus	NN
cord-104223-ht3ry9i0	149	30	.	.	.
cord-104223-ht3ry9i0	150	1	Both	both	DT
cord-104223-ht3ry9i0	150	2	amino	amino	NNS
cord-104223-ht3ry9i0	150	3	and	and	CC
cord-104223-ht3ry9i0	150	4	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	150	5	terminal	terminal	NN
cord-104223-ht3ry9i0	150	6	-	-	HYPH
cord-104223-ht3ry9i0	150	7	associated	associate	VBN
cord-104223-ht3ry9i0	150	8	radioactivity	radioactivity	NN
cord-104223-ht3ry9i0	150	9	are	be	VBP
cord-104223-ht3ry9i0	150	10	transported	transport	VBN
cord-104223-ht3ry9i0	150	11	through	through	IN
cord-104223-ht3ry9i0	150	12	the	the	DT
cord-104223-ht3ry9i0	150	13	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	150	14	stacks	stack	NNS
cord-104223-ht3ry9i0	150	15	and	and	CC
cord-104223-ht3ry9i0	150	16	enter	enter	VB
cord-104223-ht3ry9i0	150	17	small	small	JJ
cord-104223-ht3ry9i0	150	18	immature	immature	JJ
cord-104223-ht3ry9i0	150	19	DCVs	dcv	NNS
cord-104223-ht3ry9i0	150	20	(	(	-LRB-
cord-104223-ht3ry9i0	150	21	defined	define	VBN
cord-104223-ht3ry9i0	150	22	by	by	IN
cord-104223-ht3ry9i0	150	23	membrane	membrane	NN
cord-104223-ht3ry9i0	150	24	extensions	extension	NNS
cord-104223-ht3ry9i0	150	25	,	,	,
cord-104223-ht3ry9i0	150	26	connection	connection	NN
cord-104223-ht3ry9i0	150	27	to	to	IN
cord-104223-ht3ry9i0	150	28	tubules	tubule	NNS
cord-104223-ht3ry9i0	150	29	,	,	,
cord-104223-ht3ry9i0	150	30	or	or	CC
cord-104223-ht3ry9i0	150	31	nonspherical	nonspherical	JJ
cord-104223-ht3ry9i0	150	32	morphology	morphology	NN
cord-104223-ht3ry9i0	150	33	)	)	-RRB-
cord-104223-ht3ry9i0	150	34	and	and	CC
cord-104223-ht3ry9i0	150	35	clear	clear	JJ
cord-104223-ht3ry9i0	150	36	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	150	37	after	after	IN
cord-104223-ht3ry9i0	150	38	a	a	DT
cord-104223-ht3ry9i0	150	39	30-min	30-min	CD
cord-104223-ht3ry9i0	150	40	pulse	pulse	NN
cord-104223-ht3ry9i0	150	41	and	and	CC
cord-104223-ht3ry9i0	150	42	30-min	30-min	CD
cord-104223-ht3ry9i0	150	43	chase	chase	NN
cord-104223-ht3ry9i0	150	44	(	(	-LRB-
cord-104223-ht3ry9i0	150	45	Fig	Fig	NNP
cord-104223-ht3ry9i0	150	46	.	.	.
cord-104223-ht3ry9i0	150	47	4	4	CD
cord-104223-ht3ry9i0	150	48	B	b	NN
cord-104223-ht3ry9i0	150	49	,	,	,
cord-104223-ht3ry9i0	150	50	Fig	Fig	NNP
cord-104223-ht3ry9i0	150	51	.	.	NNP
cord-104223-ht3ry9i0	150	52	5	5	CD
cord-104223-ht3ry9i0	150	53	,	,	,
cord-104223-ht3ry9i0	150	54	and	and	CC
cord-104223-ht3ry9i0	150	55	Table	Table	NNP
cord-104223-ht3ry9i0	150	56	I	i	CD
cord-104223-ht3ry9i0	150	57	)	)	-RRB-
cord-104223-ht3ry9i0	150	58	.	.	.
cord-104223-ht3ry9i0	151	1	This	this	DT
cord-104223-ht3ry9i0	151	2	is	be	VBZ
cord-104223-ht3ry9i0	151	3	the	the	DT
cord-104223-ht3ry9i0	151	4	time	time	NN
cord-104223-ht3ry9i0	151	5	point	point	NN
cord-104223-ht3ry9i0	151	6	correlated	correlate	VBN
cord-104223-ht3ry9i0	151	7	with	with	IN
cord-104223-ht3ry9i0	151	8	the	the	DT
cord-104223-ht3ry9i0	151	9	initial	initial	JJ
cord-104223-ht3ry9i0	151	10	cleavage	cleavage	NN
cord-104223-ht3ry9i0	151	11	of	of	IN
cord-104223-ht3ry9i0	151	12	the	the	DT
cord-104223-ht3ry9i0	151	13	prohormone	prohormone	NN
cord-104223-ht3ry9i0	151	14	(	(	-LRB-
cord-104223-ht3ry9i0	151	15	Fig	Fig	NNP
cord-104223-ht3ry9i0	151	16	.	.	NNP
cord-104223-ht3ry9i0	151	17	2	2	CD
cord-104223-ht3ry9i0	151	18	,	,	,
cord-104223-ht3ry9i0	151	19	A	a	NN
cord-104223-ht3ry9i0	151	20	and	and	CC
cord-104223-ht3ry9i0	151	21	B	b	NN
cord-104223-ht3ry9i0	151	22	)	)	-RRB-
cord-104223-ht3ry9i0	151	23	.	.	.
cord-104223-ht3ry9i0	152	1	After	after	IN
cord-104223-ht3ry9i0	152	2	a	a	DT
cord-104223-ht3ry9i0	152	3	30-min	30-min	CD
cord-104223-ht3ry9i0	152	4	pulse	pulse	NN
cord-104223-ht3ry9i0	152	5	and	and	CC
cord-104223-ht3ry9i0	152	6	2-h	2-h	CD
cord-104223-ht3ry9i0	152	7	chase	chase	NN
cord-104223-ht3ry9i0	152	8	with	with	IN
cord-104223-ht3ry9i0	152	9	[	[	-LRB-
cord-104223-ht3ry9i0	152	10	3H]Phe	3h]phe	CD
cord-104223-ht3ry9i0	152	11	,	,	,
cord-104223-ht3ry9i0	152	12	grains	grain	NNS
cord-104223-ht3ry9i0	152	13	are	be	VBP
cord-104223-ht3ry9i0	152	14	found	find	VBN
cord-104223-ht3ry9i0	152	15	predominantly	predominantly	RB
cord-104223-ht3ry9i0	152	16	over	over	IN
cord-104223-ht3ry9i0	152	17	large	large	JJ
cord-104223-ht3ry9i0	152	18	immature	immature	JJ
cord-104223-ht3ry9i0	152	19	DCVs	dcv	NNS
cord-104223-ht3ry9i0	152	20	(	(	-LRB-
cord-104223-ht3ry9i0	152	21	Fig	fig	NN
cord-104223-ht3ry9i0	152	22	.	.	.
cord-104223-ht3ry9i0	152	23	4	4	CD
cord-104223-ht3ry9i0	152	24	 	 	_SP
cord-104223-ht3ry9i0	152	25	C	C	NNP
cord-104223-ht3ry9i0	152	26	,	,	,
cord-104223-ht3ry9i0	152	27	Fig	Fig	NNP
cord-104223-ht3ry9i0	152	28	.	.	NNP
cord-104223-ht3ry9i0	152	29	5	5	CD
cord-104223-ht3ry9i0	152	30	,	,	,
cord-104223-ht3ry9i0	152	31	and	and	CC
cord-104223-ht3ry9i0	152	32	Table	Table	NNP
cord-104223-ht3ry9i0	152	33	I	I	NNP
cord-104223-ht3ry9i0	152	34	)	)	-RRB-
cord-104223-ht3ry9i0	152	35	,	,	,
cord-104223-ht3ry9i0	152	36	while	while	IN
cord-104223-ht3ry9i0	152	37	grains	grain	NNS
cord-104223-ht3ry9i0	152	38	are	be	VBP
cord-104223-ht3ry9i0	152	39	found	find	VBN
cord-104223-ht3ry9i0	152	40	predominantly	predominantly	RB
cord-104223-ht3ry9i0	152	41	over	over	IN
cord-104223-ht3ry9i0	152	42	small	small	JJ
cord-104223-ht3ry9i0	152	43	immature	immature	JJ
cord-104223-ht3ry9i0	152	44	DCVs	dcv	NNS
cord-104223-ht3ry9i0	152	45	at	at	IN
cord-104223-ht3ry9i0	152	46	this	this	DT
cord-104223-ht3ry9i0	152	47	time	time	NN
cord-104223-ht3ry9i0	152	48	point	point	NN
cord-104223-ht3ry9i0	152	49	when	when	WRB
cord-104223-ht3ry9i0	152	50	[	[	-LRB-
cord-104223-ht3ry9i0	152	51	3H]Ile	3h]ile	CD
cord-104223-ht3ry9i0	152	52	is	be	VBZ
cord-104223-ht3ry9i0	152	53	used	use	VBN
cord-104223-ht3ry9i0	152	54	(	(	-LRB-
cord-104223-ht3ry9i0	152	55	Fig	Fig	NNP
cord-104223-ht3ry9i0	152	56	.	.	.
cord-104223-ht3ry9i0	152	57	4	4	CD
cord-104223-ht3ry9i0	152	58	D	d	NN
cord-104223-ht3ry9i0	152	59	,	,	,
cord-104223-ht3ry9i0	152	60	Fig	Fig	NNP
cord-104223-ht3ry9i0	152	61	.	.	NNP
cord-104223-ht3ry9i0	152	62	5	5	CD
cord-104223-ht3ry9i0	152	63	,	,	,
cord-104223-ht3ry9i0	152	64	and	and	CC
cord-104223-ht3ry9i0	152	65	Table	Table	NNP
cord-104223-ht3ry9i0	152	66	I	i	CD
cord-104223-ht3ry9i0	152	67	)	)	-RRB-
cord-104223-ht3ry9i0	152	68	.	.	.
cord-104223-ht3ry9i0	153	1	Therefore	therefore	RB
cord-104223-ht3ry9i0	153	2	,	,	,
cord-104223-ht3ry9i0	153	3	we	-PRON-	PRP
cord-104223-ht3ry9i0	153	4	can	can	MD
cord-104223-ht3ry9i0	153	5	conclude	conclude	VB
cord-104223-ht3ry9i0	153	6	that	that	IN
cord-104223-ht3ry9i0	153	7	after	after	IN
cord-104223-ht3ry9i0	153	8	a	a	DT
cord-104223-ht3ry9i0	153	9	30-min	30-min	CD
cord-104223-ht3ry9i0	153	10	pulse	pulse	NN
cord-104223-ht3ry9i0	153	11	and	and	CC
cord-104223-ht3ry9i0	153	12	2-h	2-h	CD
cord-104223-ht3ry9i0	153	13	chase	chase	NN
cord-104223-ht3ry9i0	153	14	,	,	,
cord-104223-ht3ry9i0	153	15	the	the	DT
cord-104223-ht3ry9i0	153	16	two	two	CD
cord-104223-ht3ry9i0	153	17	regions	region	NNS
cord-104223-ht3ry9i0	153	18	of	of	IN
cord-104223-ht3ry9i0	153	19	the	the	DT
cord-104223-ht3ry9i0	153	20	ELH	ELH	NNP
cord-104223-ht3ry9i0	153	21	prohormone	prohormone	NN
cord-104223-ht3ry9i0	153	22	have	have	VBP
cord-104223-ht3ry9i0	153	23	been	be	VBN
cord-104223-ht3ry9i0	153	24	sorted	sort	VBN
cord-104223-ht3ry9i0	153	25	into	into	IN
cord-104223-ht3ry9i0	153	26	distinct	distinct	JJ
cord-104223-ht3ry9i0	153	27	compartments	compartment	NNS
cord-104223-ht3ry9i0	153	28	.	.	.
cord-104223-ht3ry9i0	154	1	The	the	DT
cord-104223-ht3ry9i0	154	2	EM	EM	NNP
cord-104223-ht3ry9i0	154	3	autoradiographic	autoradiographic	NNP
cord-104223-ht3ry9i0	154	4	results	result	NNS
cord-104223-ht3ry9i0	154	5	are	be	VBP
cord-104223-ht3ry9i0	154	6	a	a	DT
cord-104223-ht3ry9i0	154	7	strong	strong	JJ
cord-104223-ht3ry9i0	154	8	independent	independent	JJ
cord-104223-ht3ry9i0	154	9	confirmation	confirmation	NN
cord-104223-ht3ry9i0	154	10	of	of	IN
cord-104223-ht3ry9i0	154	11	immunohistochemical	immunohistochemical	JJ
cord-104223-ht3ry9i0	154	12	studies	study	NNS
cord-104223-ht3ry9i0	154	13	demonstrating	demonstrate	VBG
cord-104223-ht3ry9i0	154	14	that	that	IN
cord-104223-ht3ry9i0	154	15	large	large	JJ
cord-104223-ht3ry9i0	154	16	DCVs	dcv	NNS
cord-104223-ht3ry9i0	154	17	contain	contain	VBP
cord-104223-ht3ry9i0	154	18	more	more	JJR
cord-104223-ht3ry9i0	154	19	immunoreactivity	immunoreactivity	NN
cord-104223-ht3ry9i0	154	20	from	from	IN
cord-104223-ht3ry9i0	154	21	amino	amino	NN
cord-104223-ht3ry9i0	154	22	terminal	terminal	NN
cord-104223-ht3ry9i0	154	23	-	-	HYPH
cord-104223-ht3ry9i0	154	24	derived	derive	VBN
cord-104223-ht3ry9i0	154	25	(	(	-LRB-
cord-104223-ht3ry9i0	154	26	Phe	Phe	NNP
cord-104223-ht3ry9i0	154	27	)	)	-RRB-
cord-104223-ht3ry9i0	154	28	peptides	peptide	NNS
cord-104223-ht3ry9i0	154	29	,	,	,
cord-104223-ht3ry9i0	154	30	while	while	IN
cord-104223-ht3ry9i0	154	31	the	the	DT
cord-104223-ht3ry9i0	154	32	majority	majority	NN
cord-104223-ht3ry9i0	154	33	of	of	IN
cord-104223-ht3ry9i0	154	34	small	small	JJ
cord-104223-ht3ry9i0	154	35	DCVs	dcv	NNS
cord-104223-ht3ry9i0	154	36	contain	contain	VBP
cord-104223-ht3ry9i0	154	37	more	more	JJR
cord-104223-ht3ry9i0	154	38	immunoreactivity	immunoreactivity	NN
cord-104223-ht3ry9i0	154	39	from	from	IN
cord-104223-ht3ry9i0	154	40	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	154	41	terminal	terminal	NN
cord-104223-ht3ry9i0	154	42	-	-	HYPH
cord-104223-ht3ry9i0	154	43	derived	derive	VBN
cord-104223-ht3ry9i0	154	44	(	(	-LRB-
cord-104223-ht3ry9i0	154	45	lie	lie	NN
cord-104223-ht3ry9i0	154	46	)	)	-RRB-
cord-104223-ht3ry9i0	154	47	peptides	peptide	NNS
cord-104223-ht3ry9i0	155	1	Kreiner	Kreiner	NNP
cord-104223-ht3ry9i0	155	2	et	et	NNP
cord-104223-ht3ry9i0	155	3	al	al	NNP
cord-104223-ht3ry9i0	155	4	.	.	NNP
cord-104223-ht3ry9i0	155	5	,	,	,
cord-104223-ht3ry9i0	155	6	1989	1989	CD
cord-104223-ht3ry9i0	155	7	)	)	-RRB-
cord-104223-ht3ry9i0	155	8	.	.	.
cord-104223-ht3ry9i0	156	1	To	to	TO
cord-104223-ht3ry9i0	156	2	look	look	VB
cord-104223-ht3ry9i0	156	3	more	more	RBR
cord-104223-ht3ry9i0	156	4	closely	closely	RB
cord-104223-ht3ry9i0	156	5	at	at	IN
cord-104223-ht3ry9i0	156	6	the	the	DT
cord-104223-ht3ry9i0	156	7	movement	movement	NN
cord-104223-ht3ry9i0	156	8	of	of	IN
cord-104223-ht3ry9i0	156	9	the	the	DT
cord-104223-ht3ry9i0	156	10	aminoterminal	aminoterminal	JJ
cord-104223-ht3ry9i0	156	11	intermediate	intermediate	NN
cord-104223-ht3ry9i0	156	12	from	from	IN
cord-104223-ht3ry9i0	156	13	small	small	JJ
cord-104223-ht3ry9i0	156	14	to	to	TO
cord-104223-ht3ry9i0	156	15	large	large	JJ
cord-104223-ht3ry9i0	156	16	immature	immature	JJ
cord-104223-ht3ry9i0	156	17	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	156	18	,	,	,
cord-104223-ht3ry9i0	156	19	a	a	DT
cord-104223-ht3ry9i0	156	20	number	number	NN
cord-104223-ht3ry9i0	156	21	of	of	IN
cord-104223-ht3ry9i0	156	22	experiments	experiment	NNS
cord-104223-ht3ry9i0	156	23	were	be	VBD
cord-104223-ht3ry9i0	156	24	done	do	VBN
cord-104223-ht3ry9i0	156	25	using	use	VBG
cord-104223-ht3ry9i0	156	26	5-min	5-min	JJ
cord-104223-ht3ry9i0	156	27	pulses	pulse	NNS
cord-104223-ht3ry9i0	156	28	of	of	IN
cord-104223-ht3ry9i0	156	29	[	[	-LRB-
cord-104223-ht3ry9i0	156	30	3H]Phe	3h]phe	CD
cord-104223-ht3ry9i0	156	31	(	(	-LRB-
cord-104223-ht3ry9i0	156	32	Table	table	NN
cord-104223-ht3ry9i0	156	33	I	i	CD
cord-104223-ht3ry9i0	156	34	)	)	-RRB-
cord-104223-ht3ry9i0	156	35	.	.	.
cord-104223-ht3ry9i0	157	1	The	the	DT
cord-104223-ht3ry9i0	157	2	movement	movement	NN
cord-104223-ht3ry9i0	157	3	from	from	IN
cord-104223-ht3ry9i0	157	4	small	small	JJ
cord-104223-ht3ry9i0	157	5	to	to	IN
cord-104223-ht3ry9i0	157	6	large	large	JJ
cord-104223-ht3ry9i0	157	7	DCVs	dcv	NNS
cord-104223-ht3ry9i0	157	8	occurs	occur	VBZ
cord-104223-ht3ry9i0	157	9	quickly	quickly	RB
cord-104223-ht3ry9i0	157	10	(	(	-LRB-
cord-104223-ht3ry9i0	157	11	largely	largely	RB
cord-104223-ht3ry9i0	157	12	between	between	IN
cord-104223-ht3ry9i0	157	13	30	30	CD
cord-104223-ht3ry9i0	157	14	and	and	CC
cord-104223-ht3ry9i0	157	15	45	45	CD
cord-104223-ht3ry9i0	157	16	min	min	NN
cord-104223-ht3ry9i0	157	17	of	of	IN
cord-104223-ht3ry9i0	157	18	chase	chase	NNP
cord-104223-ht3ry9i0	157	19	)	)	-RRB-
cord-104223-ht3ry9i0	157	20	,	,	,
cord-104223-ht3ry9i0	157	21	and	and	CC
cord-104223-ht3ry9i0	157	22	a	a	DT
cord-104223-ht3ry9i0	157	23	large	large	JJ
cord-104223-ht3ry9i0	157	24	percentage	percentage	NN
cord-104223-ht3ry9i0	157	25	of	of	IN
cord-104223-ht3ry9i0	157	26	counts	count	NNS
cord-104223-ht3ry9i0	157	27	are	be	VBP
cord-104223-ht3ry9i0	157	28	also	also	RB
cord-104223-ht3ry9i0	157	29	seen	see	VBN
cord-104223-ht3ry9i0	157	30	in	in	IN
cord-104223-ht3ry9i0	157	31	clear	clear	JJ
cord-104223-ht3ry9i0	157	32	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	157	33	at	at	IN
cord-104223-ht3ry9i0	157	34	these	these	DT
cord-104223-ht3ry9i0	157	35	time	time	NN
cord-104223-ht3ry9i0	157	36	points	point	NNS
cord-104223-ht3ry9i0	157	37	.	.	.
cord-104223-ht3ry9i0	158	1	The	the	DT
cord-104223-ht3ry9i0	158	2	vectorial	vectorial	JJ
cord-104223-ht3ry9i0	158	3	flow	flow	NN
cord-104223-ht3ry9i0	158	4	of	of	IN
cord-104223-ht3ry9i0	158	5	the	the	DT
cord-104223-ht3ry9i0	158	6	amino	amino	NN
cord-104223-ht3ry9i0	158	7	-	-	HYPH
cord-104223-ht3ry9i0	158	8	terminal	terminal	NN
cord-104223-ht3ry9i0	158	9	portion	portion	NN
cord-104223-ht3ry9i0	158	10	of	of	IN
cord-104223-ht3ry9i0	158	11	the	the	DT
cord-104223-ht3ry9i0	158	12	precursor	precursor	NN
cord-104223-ht3ry9i0	158	13	appears	appear	VBZ
cord-104223-ht3ry9i0	158	14	to	to	TO
cord-104223-ht3ry9i0	158	15	be	be	VB
cord-104223-ht3ry9i0	158	16	from	from	IN
cord-104223-ht3ry9i0	158	17	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	158	18	apparatus	apparatus	NN
cord-104223-ht3ry9i0	158	19	to	to	IN
cord-104223-ht3ry9i0	158	20	clear	clear	JJ
cord-104223-ht3ry9i0	158	21	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	158	22	and	and	CC
cord-104223-ht3ry9i0	158	23	small	small	JJ
cord-104223-ht3ry9i0	158	24	immature	immature	JJ
cord-104223-ht3ry9i0	158	25	DCVs	dcv	NNS
cord-104223-ht3ry9i0	158	26	then	then	RB
cord-104223-ht3ry9i0	158	27	to	to	IN
cord-104223-ht3ry9i0	158	28	large	large	JJ
cord-104223-ht3ry9i0	158	29	immature	immature	JJ
cord-104223-ht3ry9i0	158	30	DCVs	dcv	NNS
cord-104223-ht3ry9i0	158	31	.	.	.
cord-104223-ht3ry9i0	159	1	The	the	DT
cord-104223-ht3ry9i0	159	2	flow	flow	NN
cord-104223-ht3ry9i0	159	3	of	of	IN
cord-104223-ht3ry9i0	159	4	the	the	DT
cord-104223-ht3ry9i0	159	5	amino	amino	NN
cord-104223-ht3ry9i0	159	6	-	-	HYPH
cord-104223-ht3ry9i0	159	7	terminal	terminal	NN
cord-104223-ht3ry9i0	159	8	intermediate	intermediate	NN
cord-104223-ht3ry9i0	159	9	from	from	IN
cord-104223-ht3ry9i0	159	10	small	small	JJ
cord-104223-ht3ry9i0	159	11	to	to	TO
cord-104223-ht3ry9i0	159	12	large	large	JJ
cord-104223-ht3ry9i0	159	13	immature	immature	JJ
cord-104223-ht3ry9i0	159	14	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	159	15	could	could	MD
cord-104223-ht3ry9i0	159	16	arise	arise	VB
cord-104223-ht3ry9i0	159	17	by	by	IN
cord-104223-ht3ry9i0	159	18	(	(	-LRB-
cord-104223-ht3ry9i0	159	19	a	a	DT
cord-104223-ht3ry9i0	159	20	)	)	-RRB-
cord-104223-ht3ry9i0	159	21	distinct	distinct	JJ
cord-104223-ht3ry9i0	159	22	aminoterminal	aminoterminal	JJ
cord-104223-ht3ry9i0	159	23	specific	specific	JJ
cord-104223-ht3ry9i0	159	24	small	small	JJ
cord-104223-ht3ry9i0	159	25	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	159	26	increasing	increase	VBG
cord-104223-ht3ry9i0	159	27	in	in	IN
cord-104223-ht3ry9i0	159	28	size	size	NN
cord-104223-ht3ry9i0	159	29	or	or	CC
cord-104223-ht3ry9i0	159	30	(	(	-LRB-
cord-104223-ht3ry9i0	159	31	b	b	NN
cord-104223-ht3ry9i0	159	32	)	)	-RRB-
cord-104223-ht3ry9i0	159	33	movement	movement	NN
cord-104223-ht3ry9i0	159	34	of	of	IN
cord-104223-ht3ry9i0	159	35	the	the	DT
cord-104223-ht3ry9i0	159	36	amino	amino	NN
cord-104223-ht3ry9i0	159	37	-	-	HYPH
cord-104223-ht3ry9i0	159	38	terminal	terminal	NN
cord-104223-ht3ry9i0	159	39	intermediate	intermediate	NN
cord-104223-ht3ry9i0	159	40	from	from	IN
cord-104223-ht3ry9i0	159	41	small	small	JJ
cord-104223-ht3ry9i0	159	42	immature	immature	JJ
cord-104223-ht3ry9i0	159	43	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	159	44	containing	contain	VBG
cord-104223-ht3ry9i0	159	45	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	159	46	-	-	HYPH
cord-104223-ht3ry9i0	159	47	terminal	terminal	NN
cord-104223-ht3ry9i0	159	48	intermediates	intermediate	NNS
cord-104223-ht3ry9i0	159	49	to	to	IN
cord-104223-ht3ry9i0	159	50	a	a	DT
cord-104223-ht3ry9i0	159	51	distinct	distinct	JJ
cord-104223-ht3ry9i0	159	52	class	class	NN
cord-104223-ht3ry9i0	159	53	of	of	IN
cord-104223-ht3ry9i0	159	54	large	large	JJ
cord-104223-ht3ry9i0	159	55	immature	immature	JJ
cord-104223-ht3ry9i0	159	56	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	159	57	.	.	.
cord-104223-ht3ry9i0	160	1	We	-PRON-	PRP
cord-104223-ht3ry9i0	160	2	favor	favor	VBP
cord-104223-ht3ry9i0	160	3	the	the	DT
cord-104223-ht3ry9i0	160	4	second	second	JJ
cord-104223-ht3ry9i0	160	5	possibility	possibility	NN
cord-104223-ht3ry9i0	160	6	due	due	IN
cord-104223-ht3ry9i0	160	7	to	to	IN
cord-104223-ht3ry9i0	160	8	the	the	DT
cord-104223-ht3ry9i0	160	9	fact	fact	NN
cord-104223-ht3ry9i0	160	10	that	that	IN
cord-104223-ht3ry9i0	160	11	we	-PRON-	PRP
cord-104223-ht3ry9i0	160	12	do	do	VBP
cord-104223-ht3ry9i0	160	13	not	not	RB
cord-104223-ht3ry9i0	160	14	see	see	VB
cord-104223-ht3ry9i0	160	15	a	a	DT
cord-104223-ht3ry9i0	160	16	gradual	gradual	JJ
cord-104223-ht3ry9i0	160	17	increase	increase	NN
cord-104223-ht3ry9i0	160	18	in	in	IN
cord-104223-ht3ry9i0	160	19	the	the	DT
cord-104223-ht3ry9i0	160	20	size	size	NN
cord-104223-ht3ry9i0	160	21	of	of	IN
cord-104223-ht3ry9i0	160	22	Phe	Phe	NNP
cord-104223-ht3ry9i0	160	23	-	-	HYPH
cord-104223-ht3ry9i0	160	24	labeled	label	VBN
cord-104223-ht3ry9i0	160	25	immature	immature	JJ
cord-104223-ht3ry9i0	160	26	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	160	27	the	the	DT
cord-104223-ht3ry9i0	160	28	bag	bag	NN
cord-104223-ht3ry9i0	160	29	cell	cell	NN
cord-104223-ht3ry9i0	160	30	soma	soma	NNP
cord-104223-ht3ry9i0	160	31	,	,	,
cord-104223-ht3ry9i0	160	32	some	some	DT
cord-104223-ht3ry9i0	160	33	of	of	IN
cord-104223-ht3ry9i0	160	34	which	which	WDT
cord-104223-ht3ry9i0	160	35	contain	contain	VBP
cord-104223-ht3ry9i0	160	36	dense	dense	JJ
cord-104223-ht3ry9i0	160	37	cores	core	NNS
cord-104223-ht3ry9i0	160	38	.	.	.
cord-104223-ht3ry9i0	161	1	The	the	DT
cord-104223-ht3ry9i0	161	2	small	small	JJ
cord-104223-ht3ry9i0	161	3	and	and	CC
cord-104223-ht3ry9i0	161	4	large	large	JJ
cord-104223-ht3ry9i0	161	5	arrows	arrow	NNS
cord-104223-ht3ry9i0	161	6	identify	identify	VBP
cord-104223-ht3ry9i0	161	7	two	two	CD
cord-104223-ht3ry9i0	161	8	dense	dense	JJ
cord-104223-ht3ry9i0	161	9	cores	core	NNS
cord-104223-ht3ry9i0	161	10	within	within	IN
cord-104223-ht3ry9i0	161	11	a	a	DT
cord-104223-ht3ry9i0	161	12	single	single	JJ
cord-104223-ht3ry9i0	161	13	vacuole	vacuole	NN
cord-104223-ht3ry9i0	161	14	that	that	WDT
cord-104223-ht3ry9i0	161	15	appear	appear	VBP
cord-104223-ht3ry9i0	161	16	to	to	TO
cord-104223-ht3ry9i0	161	17	be	be	VB
cord-104223-ht3ry9i0	161	18	of	of	IN
cord-104223-ht3ry9i0	161	19	different	different	JJ
cord-104223-ht3ry9i0	161	20	composition	composition	NN
cord-104223-ht3ry9i0	161	21	.	.	.
cord-104223-ht3ry9i0	162	1	About	about	RB
cord-104223-ht3ry9i0	162	2	10	10	CD
cord-104223-ht3ry9i0	162	3	-	-	SYM
cord-104223-ht3ry9i0	162	4	20	20	CD
cord-104223-ht3ry9i0	162	5	%	%	NN
cord-104223-ht3ry9i0	162	6	of	of	IN
cord-104223-ht3ry9i0	162	7	the	the	DT
cord-104223-ht3ry9i0	162	8	densities	density	NNS
cord-104223-ht3ry9i0	162	9	in	in	IN
cord-104223-ht3ry9i0	162	10	vacuoles	vacuole	NNS
cord-104223-ht3ry9i0	162	11	had	have	VBD
cord-104223-ht3ry9i0	162	12	this	this	DT
cord-104223-ht3ry9i0	162	13	appearance	appearance	NN
cord-104223-ht3ry9i0	162	14	.	.	.
cord-104223-ht3ry9i0	163	1	(	(	-LRB-
cord-104223-ht3ry9i0	163	2	B	b	NN
cord-104223-ht3ry9i0	163	3	)	)	-RRB-
cord-104223-ht3ry9i0	163	4	Immunoelectron	Immunoelectron	NNP
cord-104223-ht3ry9i0	163	5	microscopic	microscopic	JJ
cord-104223-ht3ry9i0	163	6	analysis	analysis	NN
cord-104223-ht3ry9i0	163	7	of	of	IN
cord-104223-ht3ry9i0	163	8	monensin	monensin	NNP
cord-104223-ht3ry9i0	163	9	-	-	HYPH
cord-104223-ht3ry9i0	163	10	treated	treat	VBN
cord-104223-ht3ry9i0	163	11	bag	bag	NN
cord-104223-ht3ry9i0	163	12	cells	cell	NNS
cord-104223-ht3ry9i0	163	13	.	.	.
cord-104223-ht3ry9i0	164	1	Bag	bag	NN
cord-104223-ht3ry9i0	164	2	cell	cell	NN
cord-104223-ht3ry9i0	164	3	sections	section	NNS
cord-104223-ht3ry9i0	164	4	were	be	VBD
cord-104223-ht3ry9i0	164	5	labeled	label	VBN
cord-104223-ht3ry9i0	164	6	with	with	IN
cord-104223-ht3ry9i0	164	7	a	a	DT
cord-104223-ht3ry9i0	164	8	rabbit	rabbit	NN
cord-104223-ht3ry9i0	164	9	anti	anti	JJ
cord-104223-ht3ry9i0	164	10	-	-	JJ
cord-104223-ht3ry9i0	164	11	peptide	peptide	JJ
cord-104223-ht3ry9i0	164	12	K	K	NNP
cord-104223-ht3ry9i0	164	13	and	and	CC
cord-104223-ht3ry9i0	164	14	a	a	DT
cord-104223-ht3ry9i0	164	15	rat	rat	NN
cord-104223-ht3ry9i0	164	16	anti	anti	JJ
cord-104223-ht3ry9i0	164	17	-	-	JJ
cord-104223-ht3ry9i0	164	18	ELH	ELH	NNP
cord-104223-ht3ry9i0	164	19	primary	primary	JJ
cord-104223-ht3ry9i0	164	20	antibody	antibody	NN
cord-104223-ht3ry9i0	164	21	followed	follow	VBN
cord-104223-ht3ry9i0	164	22	by	by	IN
cord-104223-ht3ry9i0	164	23	a	a	DT
cord-104223-ht3ry9i0	164	24	5-nm	5-nm	CD
cord-104223-ht3ry9i0	164	25	colloidal	colloidal	NN
cord-104223-ht3ry9i0	164	26	gold	gold	NN
cord-104223-ht3ry9i0	164	27	anti	anti	JJ
cord-104223-ht3ry9i0	164	28	-	-	JJ
cord-104223-ht3ry9i0	164	29	rabbit	rabbit	NN
cord-104223-ht3ry9i0	164	30	and	and	CC
cord-104223-ht3ry9i0	164	31	10-nm	10-nm	CD
cord-104223-ht3ry9i0	164	32	colloidal	colloidal	NN
cord-104223-ht3ry9i0	164	33	gold	gold	NN
cord-104223-ht3ry9i0	164	34	anti	anti	JJ
cord-104223-ht3ry9i0	164	35	-	-	JJ
cord-104223-ht3ry9i0	164	36	rat	rat	JJ
cord-104223-ht3ry9i0	164	37	secondary	secondary	JJ
cord-104223-ht3ry9i0	164	38	antibodies	antibody	NNS
cord-104223-ht3ry9i0	164	39	.	.	.
cord-104223-ht3ry9i0	165	1	Immunoreactivity	Immunoreactivity	NNP
cord-104223-ht3ry9i0	165	2	within	within	IN
cord-104223-ht3ry9i0	165	3	the	the	DT
cord-104223-ht3ry9i0	165	4	dense	dense	JJ
cord-104223-ht3ry9i0	165	5	cores	core	NNS
cord-104223-ht3ry9i0	165	6	is	be	VBZ
cord-104223-ht3ry9i0	165	7	segregated	segregate	VBN
cord-104223-ht3ry9i0	165	8	;	;	:
cord-104223-ht3ry9i0	165	9	the	the	DT
cord-104223-ht3ry9i0	165	10	small	small	JJ
cord-104223-ht3ry9i0	165	11	arrow	arrow	NN
cord-104223-ht3ry9i0	165	12	points	point	NNS
cord-104223-ht3ry9i0	165	13	to	to	IN
cord-104223-ht3ry9i0	165	14	peptide	peptide	NN
cord-104223-ht3ry9i0	165	15	K	K	NNP
cord-104223-ht3ry9i0	165	16	immunoreactivity	immunoreactivity	NN
cord-104223-ht3ry9i0	165	17	,	,	,
cord-104223-ht3ry9i0	165	18	and	and	CC
cord-104223-ht3ry9i0	165	19	the	the	DT
cord-104223-ht3ry9i0	165	20	large	large	JJ
cord-104223-ht3ry9i0	165	21	arrow	arrow	NN
cord-104223-ht3ry9i0	165	22	points	point	NNS
cord-104223-ht3ry9i0	165	23	to	to	IN
cord-104223-ht3ry9i0	165	24	ELH	ELH	NNP
cord-104223-ht3ry9i0	165	25	immunoreaetivity	immunoreaetivity	NN
cord-104223-ht3ry9i0	165	26	.	.	.
cord-104223-ht3ry9i0	166	1	(	(	-LRB-
cord-104223-ht3ry9i0	166	2	see	see	VB
cord-104223-ht3ry9i0	166	3	Materials	material	NNS
cord-104223-ht3ry9i0	166	4	and	and	CC
cord-104223-ht3ry9i0	166	5	Methods	Methods	NNPS
cord-104223-ht3ry9i0	166	6	)	)	-RRB-
cord-104223-ht3ry9i0	166	7	but	but	CC
cord-104223-ht3ry9i0	166	8	do	do	VB
cord-104223-ht3ry9i0	166	9	observe	observe	VB
cord-104223-ht3ry9i0	166	10	an	an	DT
cord-104223-ht3ry9i0	166	11	abrupt	abrupt	JJ
cord-104223-ht3ry9i0	166	12	change	change	NN
cord-104223-ht3ry9i0	166	13	from	from	IN
cord-104223-ht3ry9i0	166	14	small	small	JJ
cord-104223-ht3ry9i0	166	15	to	to	IN
cord-104223-ht3ry9i0	166	16	large	large	JJ
cord-104223-ht3ry9i0	166	17	Phe	Phe	NNP
cord-104223-ht3ry9i0	166	18	-	-	HYPH
cord-104223-ht3ry9i0	166	19	labeled	label	VBN
cord-104223-ht3ry9i0	166	20	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	166	21	.	.	.
cord-104223-ht3ry9i0	167	1	Furthermore	furthermore	RB
cord-104223-ht3ry9i0	167	2	,	,	,
cord-104223-ht3ry9i0	167	3	small	small	JJ
cord-104223-ht3ry9i0	167	4	immature	immature	JJ
cord-104223-ht3ry9i0	167	5	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	167	6	containing	contain	VBG
cord-104223-ht3ry9i0	167	7	amino	amino	NN
cord-104223-ht3ry9i0	167	8	-	-	HYPH
cord-104223-ht3ry9i0	167	9	terminal	terminal	NN
cord-104223-ht3ry9i0	167	10	peptides	peptide	NNS
cord-104223-ht3ry9i0	167	11	that	that	WDT
cord-104223-ht3ry9i0	167	12	are	be	VBP
cord-104223-ht3ry9i0	167	13	contiguous	contiguous	JJ
cord-104223-ht3ry9i0	167	14	with	with	IN
cord-104223-ht3ry9i0	167	15	the	the	DT
cord-104223-ht3ry9i0	167	16	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	167	17	apparatus	apparatus	NN
cord-104223-ht3ry9i0	167	18	are	be	VBP
cord-104223-ht3ry9i0	167	19	not	not	RB
cord-104223-ht3ry9i0	167	20	observed	observe	VBN
cord-104223-ht3ry9i0	167	21	,	,	,
cord-104223-ht3ry9i0	167	22	although	although	IN
cord-104223-ht3ry9i0	167	23	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	167	24	-	-	HYPH
cord-104223-ht3ry9i0	167	25	terminal	terminal	NN
cord-104223-ht3ry9i0	167	26	peptide	peptide	NN
cord-104223-ht3ry9i0	167	27	immunoreactive	immunoreactive	JJ
cord-104223-ht3ry9i0	167	28	small	small	JJ
cord-104223-ht3ry9i0	167	29	immature	immature	JJ
cord-104223-ht3ry9i0	167	30	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	167	31	are	be	VBP
cord-104223-ht3ry9i0	167	32	detected	detect	VBN
cord-104223-ht3ry9i0	167	33	.	.	.
cord-104223-ht3ry9i0	168	1	It	-PRON-	PRP
cord-104223-ht3ry9i0	168	2	is	be	VBZ
cord-104223-ht3ry9i0	168	3	possible	possible	JJ
cord-104223-ht3ry9i0	168	4	that	that	IN
cord-104223-ht3ry9i0	168	5	features	feature	NNS
cord-104223-ht3ry9i0	168	6	of	of	IN
cord-104223-ht3ry9i0	168	7	immature	immature	JJ
cord-104223-ht3ry9i0	168	8	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	168	9	may	may	MD
cord-104223-ht3ry9i0	168	10	result	result	VB
cord-104223-ht3ry9i0	168	11	from	from	IN
cord-104223-ht3ry9i0	168	12	their	-PRON-	PRP$
cord-104223-ht3ry9i0	168	13	association	association	NN
cord-104223-ht3ry9i0	168	14	with	with	IN
cord-104223-ht3ry9i0	168	15	the	the	DT
cord-104223-ht3ry9i0	168	16	TGN	TGN	NNP
cord-104223-ht3ry9i0	168	17	.	.	.
cord-104223-ht3ry9i0	169	1	A	a	DT
cord-104223-ht3ry9i0	169	2	standard	standard	JJ
cord-104223-ht3ry9i0	169	3	marker	marker	NN
cord-104223-ht3ry9i0	169	4	for	for	IN
cord-104223-ht3ry9i0	169	5	the	the	DT
cord-104223-ht3ry9i0	169	6	TGN	TGN	NNP
cord-104223-ht3ry9i0	169	7	is	be	VBZ
cord-104223-ht3ry9i0	169	8	acid	acid	JJ
cord-104223-ht3ry9i0	169	9	phosphatase	phosphatase	NN
cord-104223-ht3ry9i0	169	10	(	(	-LRB-
cord-104223-ht3ry9i0	169	11	Grifiiths	Grifiiths	NNP
cord-104223-ht3ry9i0	169	12	and	and	CC
cord-104223-ht3ry9i0	169	13	Simons	Simons	NNP
cord-104223-ht3ry9i0	169	14	,	,	,
cord-104223-ht3ry9i0	169	15	1986	1986	CD
cord-104223-ht3ry9i0	169	16	)	)	-RRB-
cord-104223-ht3ry9i0	169	17	,	,	,
cord-104223-ht3ry9i0	169	18	and	and	CC
cord-104223-ht3ry9i0	169	19	,	,	,
cord-104223-ht3ry9i0	169	20	as	as	IN
cord-104223-ht3ry9i0	169	21	illustrated	illustrate	VBN
cord-104223-ht3ry9i0	169	22	in	in	IN
cord-104223-ht3ry9i0	169	23	Fig	Fig	NNP
cord-104223-ht3ry9i0	169	24	.	.	.
cord-104223-ht3ry9i0	170	1	6	6	LS
cord-104223-ht3ry9i0	170	2	,	,	,
cord-104223-ht3ry9i0	170	3	A	A	NNP
cord-104223-ht3ry9i0	170	4	-	-	HYPH
cord-104223-ht3ry9i0	170	5	C	C	NNP
cord-104223-ht3ry9i0	170	6	,	,	,
cord-104223-ht3ry9i0	170	7	both	both	DT
cord-104223-ht3ry9i0	170	8	small	small	JJ
cord-104223-ht3ry9i0	170	9	and	and	CC
cord-104223-ht3ry9i0	170	10	large	large	JJ
cord-104223-ht3ry9i0	170	11	immature	immature	JJ
cord-104223-ht3ry9i0	170	12	vesicle	vesicle	NN
cord-104223-ht3ry9i0	170	13	membranes	membrane	NNS
cord-104223-ht3ry9i0	170	14	are	be	VBP
cord-104223-ht3ry9i0	170	15	ringed	ring	VBN
cord-104223-ht3ry9i0	170	16	by	by	IN
cord-104223-ht3ry9i0	170	17	the	the	DT
cord-104223-ht3ry9i0	170	18	lead	lead	JJ
cord-104223-ht3ry9i0	170	19	phosphate	phosphate	NN
cord-104223-ht3ry9i0	170	20	reaction	reaction	NN
cord-104223-ht3ry9i0	170	21	product	product	NN
cord-104223-ht3ry9i0	170	22	.	.	.
cord-104223-ht3ry9i0	171	1	Immature	immature	JJ
cord-104223-ht3ry9i0	171	2	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	171	3	have	have	VBP
cord-104223-ht3ry9i0	171	4	also	also	RB
cord-104223-ht3ry9i0	171	5	been	be	VBN
cord-104223-ht3ry9i0	171	6	shown	show	VBN
cord-104223-ht3ry9i0	171	7	to	to	TO
cord-104223-ht3ry9i0	171	8	contain	contain	VB
cord-104223-ht3ry9i0	171	9	acid	acid	JJ
cord-104223-ht3ry9i0	171	10	phosphatase	phosphatase	NN
cord-104223-ht3ry9i0	171	11	in	in	IN
cord-104223-ht3ry9i0	171	12	a	a	DT
cord-104223-ht3ry9i0	171	13	number	number	NN
cord-104223-ht3ry9i0	171	14	of	of	IN
cord-104223-ht3ry9i0	171	15	other	other	JJ
cord-104223-ht3ry9i0	171	16	systems	system	NNS
cord-104223-ht3ry9i0	171	17	(	(	-LRB-
cord-104223-ht3ry9i0	171	18	Smith	Smith	NNP
cord-104223-ht3ry9i0	171	19	and	and	CC
cord-104223-ht3ry9i0	171	20	Farquhar	Farquhar	NNP
cord-104223-ht3ry9i0	171	21	,	,	,
cord-104223-ht3ry9i0	171	22	1966	1966	CD
cord-104223-ht3ry9i0	171	23	;	;	:
cord-104223-ht3ry9i0	171	24	Novikoff	Novikoff	NNP
cord-104223-ht3ry9i0	171	25	et	et	NNP
cord-104223-ht3ry9i0	171	26	al	al	NNP
cord-104223-ht3ry9i0	171	27	.	.	NNP
cord-104223-ht3ry9i0	171	28	,	,	,
cord-104223-ht3ry9i0	171	29	1971	1971	CD
cord-104223-ht3ry9i0	171	30	;	;	:
cord-104223-ht3ry9i0	171	31	Hand	Hand	NNP
cord-104223-ht3ry9i0	171	32	and	and	CC
cord-104223-ht3ry9i0	171	33	Oliver	Oliver	NNP
cord-104223-ht3ry9i0	171	34	,	,	,
cord-104223-ht3ry9i0	171	35	1977	1977	CD
cord-104223-ht3ry9i0	171	36	)	)	-RRB-
cord-104223-ht3ry9i0	171	37	.	.	.
cord-104223-ht3ry9i0	172	1	Fig	Fig	NNP
cord-104223-ht3ry9i0	172	2	.	.	.
cord-104223-ht3ry9i0	173	1	6	6	LS
cord-104223-ht3ry9i0	173	2	,	,	,
cord-104223-ht3ry9i0	173	3	A	A	NNP
cord-104223-ht3ry9i0	173	4	-	-	HYPH
cord-104223-ht3ry9i0	173	5	C	C	NNP
cord-104223-ht3ry9i0	173	6	,	,	,
cord-104223-ht3ry9i0	173	7	shows	show	VBZ
cord-104223-ht3ry9i0	173	8	a	a	DT
cord-104223-ht3ry9i0	173	9	series	series	NN
cord-104223-ht3ry9i0	173	10	of	of	IN
cord-104223-ht3ry9i0	173	11	micrographs	micrograph	NNS
cord-104223-ht3ry9i0	173	12	from	from	IN
cord-104223-ht3ry9i0	173	13	a	a	DT
cord-104223-ht3ry9i0	173	14	set	set	NN
cord-104223-ht3ry9i0	173	15	of	of	IN
cord-104223-ht3ry9i0	173	16	serial	serial	JJ
cord-104223-ht3ry9i0	173	17	sections	section	NNS
cord-104223-ht3ry9i0	173	18	;	;	:
cord-104223-ht3ry9i0	173	19	the	the	DT
cord-104223-ht3ry9i0	173	20	structure	structure	NN
cord-104223-ht3ry9i0	173	21	marked	mark	VBN
cord-104223-ht3ry9i0	173	22	by	by	IN
cord-104223-ht3ry9i0	173	23	the	the	DT
cord-104223-ht3ry9i0	173	24	small	small	JJ
cord-104223-ht3ry9i0	173	25	arrow	arrow	NN
cord-104223-ht3ry9i0	173	26	actually	actually	RB
cord-104223-ht3ry9i0	173	27	attaches	attach	VBZ
cord-104223-ht3ry9i0	173	28	to	to	IN
cord-104223-ht3ry9i0	173	29	the	the	DT
cord-104223-ht3ry9i0	173	30	proximal	proximal	JJ
cord-104223-ht3ry9i0	173	31	large	large	JJ
cord-104223-ht3ry9i0	173	32	immature	immature	JJ
cord-104223-ht3ry9i0	173	33	vesicle	vesicle	NN
cord-104223-ht3ry9i0	173	34	(	(	-LRB-
cord-104223-ht3ry9i0	173	35	Fig	Fig	NNP
cord-104223-ht3ry9i0	173	36	.	.	.
cord-104223-ht3ry9i0	173	37	6	6	CD
cord-104223-ht3ry9i0	173	38	A	a	NN
cord-104223-ht3ry9i0	173	39	)	)	-RRB-
cord-104223-ht3ry9i0	173	40	and	and	CC
cord-104223-ht3ry9i0	173	41	in	in	IN
cord-104223-ht3ry9i0	173	42	the	the	DT
cord-104223-ht3ry9i0	173	43	next	next	JJ
cord-104223-ht3ry9i0	173	44	section	section	NN
cord-104223-ht3ry9i0	173	45	attaches	attach	VBZ
cord-104223-ht3ry9i0	173	46	to	to	IN
cord-104223-ht3ry9i0	173	47	a	a	DT
cord-104223-ht3ry9i0	173	48	small	small	JJ
cord-104223-ht3ry9i0	173	49	immature	immature	JJ
cord-104223-ht3ry9i0	173	50	vesicle	vesicle	NN
cord-104223-ht3ry9i0	174	1	(	(	-LRB-
cord-104223-ht3ry9i0	174	2	Fig	Fig	NNP
cord-104223-ht3ry9i0	174	3	.	.	.
cord-104223-ht3ry9i0	174	4	6	6	CD
cord-104223-ht3ry9i0	174	5	B	b	NN
cord-104223-ht3ry9i0	174	6	)	)	-RRB-
cord-104223-ht3ry9i0	174	7	.	.	.
cord-104223-ht3ry9i0	175	1	Many	many	JJ
cord-104223-ht3ry9i0	175	2	other	other	JJ
cord-104223-ht3ry9i0	175	3	attachments	attachment	NNS
cord-104223-ht3ry9i0	175	4	between	between	IN
cord-104223-ht3ry9i0	175	5	acid	acid	NN
cord-104223-ht3ry9i0	175	6	phosphatase	phosphatase	NN
cord-104223-ht3ry9i0	175	7	-	-	HYPH
cord-104223-ht3ry9i0	175	8	containing	contain	VBG
cord-104223-ht3ry9i0	175	9	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	175	10	are	be	VBP
cord-104223-ht3ry9i0	175	11	seen	see	VBN
cord-104223-ht3ry9i0	175	12	in	in	IN
cord-104223-ht3ry9i0	175	13	serial	serial	JJ
cord-104223-ht3ry9i0	175	14	sections	section	NNS
cord-104223-ht3ry9i0	175	15	,	,	,
cord-104223-ht3ry9i0	175	16	suggesting	suggest	VBG
cord-104223-ht3ry9i0	175	17	that	that	IN
cord-104223-ht3ry9i0	175	18	the	the	DT
cord-104223-ht3ry9i0	175	19	immature	immature	JJ
cord-104223-ht3ry9i0	175	20	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	175	21	are	be	VBP
cord-104223-ht3ry9i0	175	22	to	to	IN
cord-104223-ht3ry9i0	175	23	some	some	DT
cord-104223-ht3ry9i0	175	24	extent	extent	NN
cord-104223-ht3ry9i0	175	25	still	still	RB
cord-104223-ht3ry9i0	175	26	connected	connect	VBN
cord-104223-ht3ry9i0	175	27	to	to	IN
cord-104223-ht3ry9i0	175	28	the	the	DT
cord-104223-ht3ry9i0	175	29	tubular	tubular	JJ
cord-104223-ht3ry9i0	175	30	portion	portion	NN
cord-104223-ht3ry9i0	175	31	of	of	IN
cord-104223-ht3ry9i0	175	32	the	the	DT
cord-104223-ht3ry9i0	175	33	TGN	TGN	NNP
cord-104223-ht3ry9i0	175	34	.	.	.
cord-104223-ht3ry9i0	176	1	Mature	mature	JJ
cord-104223-ht3ry9i0	176	2	small	small	JJ
cord-104223-ht3ry9i0	176	3	and	and	CC
cord-104223-ht3ry9i0	176	4	large	large	JJ
cord-104223-ht3ry9i0	176	5	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	176	6	,	,	,
cord-104223-ht3ry9i0	176	7	as	as	RB
cord-104223-ht3ry9i0	176	8	well	well	RB
cord-104223-ht3ry9i0	176	9	as	as	IN
cord-104223-ht3ry9i0	176	10	ER	ER	NNP
cord-104223-ht3ry9i0	176	11	and	and	CC
cord-104223-ht3ry9i0	176	12	other	other	JJ
cord-104223-ht3ry9i0	176	13	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	176	14	stacks	stack	NNS
cord-104223-ht3ry9i0	176	15	,	,	,
cord-104223-ht3ry9i0	176	16	do	do	VBP
cord-104223-ht3ry9i0	176	17	not	not	RB
cord-104223-ht3ry9i0	176	18	stain	stain	VB
cord-104223-ht3ry9i0	176	19	with	with	IN
cord-104223-ht3ry9i0	176	20	acid	acid	NN
cord-104223-ht3ry9i0	176	21	phosphatase	phosphatase	NN
cord-104223-ht3ry9i0	176	22	,	,	,
cord-104223-ht3ry9i0	176	23	while	while	IN
cord-104223-ht3ry9i0	176	24	lysosomes	lysosome	NNS
cord-104223-ht3ry9i0	176	25	stain	stain	VBP
cord-104223-ht3ry9i0	176	26	intensely	intensely	RB
cord-104223-ht3ry9i0	176	27	.	.	.
cord-104223-ht3ry9i0	177	1	Double	double	JJ
cord-104223-ht3ry9i0	177	2	label	label	NN
cord-104223-ht3ry9i0	177	3	experiments	experiment	NNS
cord-104223-ht3ry9i0	177	4	which	which	WDT
cord-104223-ht3ry9i0	177	5	combine	combine	VBP
cord-104223-ht3ry9i0	177	6	EM	EM	NNP
cord-104223-ht3ry9i0	177	7	autoradiography	autoradiography	NN
cord-104223-ht3ry9i0	177	8	with	with	IN
cord-104223-ht3ry9i0	177	9	acid	acid	JJ
cord-104223-ht3ry9i0	177	10	phosphatase	phosphatase	NN
cord-104223-ht3ry9i0	177	11	treatment	treatment	NN
cord-104223-ht3ry9i0	177	12	formally	formally	RB
cord-104223-ht3ry9i0	177	13	demonstrate	demonstrate	VBP
cord-104223-ht3ry9i0	177	14	that	that	IN
cord-104223-ht3ry9i0	177	15	the	the	DT
cord-104223-ht3ry9i0	177	16	immature	immature	JJ
cord-104223-ht3ry9i0	177	17	DCVs	dcv	NNS
cord-104223-ht3ry9i0	177	18	contain	contain	VBP
cord-104223-ht3ry9i0	177	19	acid	acid	JJ
cord-104223-ht3ry9i0	177	20	phosphatase	phosphatase	NN
cord-104223-ht3ry9i0	177	21	activity	activity	NN
cord-104223-ht3ry9i0	177	22	(	(	-LRB-
cord-104223-ht3ry9i0	177	23	Fig	Fig	NNP
cord-104223-ht3ry9i0	177	24	.	.	.
cord-104223-ht3ry9i0	177	25	6	6	CD
cord-104223-ht3ry9i0	177	26	D	d	NN
cord-104223-ht3ry9i0	177	27	)	)	-RRB-
cord-104223-ht3ry9i0	177	28	and	and	CC
cord-104223-ht3ry9i0	177	29	are	be	VBP
cord-104223-ht3ry9i0	177	30	therefore	therefore	RB
cord-104223-ht3ry9i0	177	31	part	part	NN
cord-104223-ht3ry9i0	177	32	of	of	IN
cord-104223-ht3ry9i0	177	33	the	the	DT
cord-104223-ht3ry9i0	177	34	TGN	TGN	NNP
cord-104223-ht3ry9i0	177	35	.	.	.
cord-104223-ht3ry9i0	178	1	Interestingly	interestingly	RB
cord-104223-ht3ry9i0	178	2	,	,	,
cord-104223-ht3ry9i0	178	3	one	one	CD
cord-104223-ht3ry9i0	178	4	of	of	IN
cord-104223-ht3ry9i0	178	5	the	the	DT
cord-104223-ht3ry9i0	178	6	large	large	JJ
cord-104223-ht3ry9i0	178	7	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	178	8	in	in	IN
cord-104223-ht3ry9i0	178	9	this	this	DT
cord-104223-ht3ry9i0	178	10	micrograph	micrograph	NN
cord-104223-ht3ry9i0	178	11	contains	contain	VBZ
cord-104223-ht3ry9i0	178	12	only	only	RB
cord-104223-ht3ry9i0	178	13	patches	patch	NNS
cord-104223-ht3ry9i0	178	14	of	of	IN
cord-104223-ht3ry9i0	178	15	acid	acid	JJ
cord-104223-ht3ry9i0	178	16	phosphatase	phosphatase	NN
cord-104223-ht3ry9i0	178	17	reaction	reaction	NN
cord-104223-ht3ry9i0	178	18	product	product	NN
cord-104223-ht3ry9i0	178	19	.	.	.
cord-104223-ht3ry9i0	179	1	This	this	DT
cord-104223-ht3ry9i0	179	2	is	be	VBZ
cord-104223-ht3ry9i0	179	3	a	a	DT
cord-104223-ht3ry9i0	179	4	common	common	JJ
cord-104223-ht3ry9i0	179	5	occurrence	occurrence	NN
cord-104223-ht3ry9i0	179	6	and	and	CC
cord-104223-ht3ry9i0	179	7	suggests	suggest	VBZ
cord-104223-ht3ry9i0	179	8	that	that	IN
cord-104223-ht3ry9i0	179	9	the	the	DT
cord-104223-ht3ry9i0	179	10	acid	acid	NN
cord-104223-ht3ry9i0	179	11	phosphatase	phosphatase	NN
cord-104223-ht3ry9i0	179	12	is	be	VBZ
cord-104223-ht3ry9i0	179	13	removed	remove	VBN
cord-104223-ht3ry9i0	179	14	in	in	IN
cord-104223-ht3ry9i0	179	15	patches	patch	NNS
cord-104223-ht3ry9i0	179	16	from	from	IN
cord-104223-ht3ry9i0	179	17	immature	immature	JJ
cord-104223-ht3ry9i0	179	18	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	179	19	,	,	,
cord-104223-ht3ry9i0	179	20	as	as	IN
cord-104223-ht3ry9i0	179	21	opposed	oppose	VBN
cord-104223-ht3ry9i0	179	22	to	to	IN
cord-104223-ht3ry9i0	179	23	gradually	gradually	RB
cord-104223-ht3ry9i0	179	24	fading	fade	VBG
cord-104223-ht3ry9i0	179	25	in	in	IN
cord-104223-ht3ry9i0	179	26	intensity	intensity	NN
cord-104223-ht3ry9i0	179	27	.	.	.
cord-104223-ht3ry9i0	180	1	Acid	acid	NN
cord-104223-ht3ry9i0	180	2	phosphatase	phosphatase	NN
cord-104223-ht3ry9i0	180	3	is	be	VBZ
cord-104223-ht3ry9i0	180	4	an	an	DT
cord-104223-ht3ry9i0	180	5	enzyme	enzyme	NN
cord-104223-ht3ry9i0	180	6	destined	destine	VBN
cord-104223-ht3ry9i0	180	7	for	for	IN
cord-104223-ht3ry9i0	180	8	transport	transport	NN
cord-104223-ht3ry9i0	180	9	to	to	IN
cord-104223-ht3ry9i0	180	10	endosomes	endosome	NNS
cord-104223-ht3ry9i0	180	11	and	and	CC
cord-104223-ht3ry9i0	180	12	lysosomes	lysosome	NNS
cord-104223-ht3ry9i0	180	13	.	.	.
cord-104223-ht3ry9i0	181	1	The	the	DT
cord-104223-ht3ry9i0	181	2	appearance	appearance	NN
cord-104223-ht3ry9i0	181	3	of	of	IN
cord-104223-ht3ry9i0	181	4	acid	acid	JJ
cord-104223-ht3ry9i0	181	5	phosphatase	phosphatase	NN
cord-104223-ht3ry9i0	181	6	reaction	reaction	NN
cord-104223-ht3ry9i0	181	7	product	product	NN
cord-104223-ht3ry9i0	181	8	in	in	IN
cord-104223-ht3ry9i0	181	9	patches	patch	NNS
cord-104223-ht3ry9i0	181	10	suggests	suggest	VBZ
cord-104223-ht3ry9i0	181	11	that	that	IN
cord-104223-ht3ry9i0	181	12	lysosomal	lysosomal	JJ
cord-104223-ht3ry9i0	181	13	proteins	protein	NNS
cord-104223-ht3ry9i0	181	14	are	be	VBP
cord-104223-ht3ry9i0	181	15	removed	remove	VBN
cord-104223-ht3ry9i0	181	16	,	,	,
cord-104223-ht3ry9i0	181	17	not	not	RB
cord-104223-ht3ry9i0	181	18	only	only	RB
cord-104223-ht3ry9i0	181	19	from	from	IN
cord-104223-ht3ry9i0	181	20	clear	clear	JJ
cord-104223-ht3ry9i0	181	21	regions	region	NNS
cord-104223-ht3ry9i0	181	22	of	of	IN
cord-104223-ht3ry9i0	181	23	the	the	DT
cord-104223-ht3ry9i0	181	24	TGN	TGN	NNP
cord-104223-ht3ry9i0	181	25	,	,	,
cord-104223-ht3ry9i0	181	26	The	the	DT
cord-104223-ht3ry9i0	181	27	Journal	Journal	NNP
cord-104223-ht3ry9i0	181	28	of	of	IN
cord-104223-ht3ry9i0	181	29	Cell	Cell	NNP
cord-104223-ht3ry9i0	181	30	Biology	Biology	NNP
cord-104223-ht3ry9i0	181	31	,	,	,
cord-104223-ht3ry9i0	181	32	Volume	volume	NN
cord-104223-ht3ry9i0	181	33	1	1	CD
cord-104223-ht3ry9i0	181	34	I0	i0	NN
cord-104223-ht3ry9i0	181	35	,	,	,
cord-104223-ht3ry9i0	181	36	1990	1990	CD
cord-104223-ht3ry9i0	181	37	but	but	CC
cord-104223-ht3ry9i0	181	38	also	also	RB
cord-104223-ht3ry9i0	181	39	from	from	IN
cord-104223-ht3ry9i0	181	40	membranes	membrane	NNS
cord-104223-ht3ry9i0	181	41	of	of	IN
cord-104223-ht3ry9i0	181	42	immature	immature	JJ
cord-104223-ht3ry9i0	181	43	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	181	44	.	.	.
cord-104223-ht3ry9i0	182	1	Immature	immature	JJ
cord-104223-ht3ry9i0	182	2	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	182	3	often	often	RB
cord-104223-ht3ry9i0	182	4	contain	contain	VBP
cord-104223-ht3ry9i0	182	5	patches	patch	NNS
cord-104223-ht3ry9i0	182	6	of	of	IN
cord-104223-ht3ry9i0	182	7	clathrin	clathrin	NN
cord-104223-ht3ry9i0	182	8	,	,	,
cord-104223-ht3ry9i0	182	9	although	although	IN
cord-104223-ht3ry9i0	182	10	the	the	DT
cord-104223-ht3ry9i0	182	11	function	function	NN
cord-104223-ht3ry9i0	182	12	of	of	IN
cord-104223-ht3ry9i0	182	13	this	this	DT
cord-104223-ht3ry9i0	182	14	clathrin	clathrin	NN
cord-104223-ht3ry9i0	182	15	is	be	VBZ
cord-104223-ht3ry9i0	182	16	unclear	unclear	JJ
cord-104223-ht3ry9i0	182	17	.	.	.
cord-104223-ht3ry9i0	183	1	This	this	DT
cord-104223-ht3ry9i0	183	2	clathrin	clathrin	NN
cord-104223-ht3ry9i0	183	3	has	have	VBZ
cord-104223-ht3ry9i0	183	4	been	be	VBN
cord-104223-ht3ry9i0	183	5	proposed	propose	VBN
cord-104223-ht3ry9i0	183	6	to	to	TO
cord-104223-ht3ry9i0	183	7	be	be	VB
cord-104223-ht3ry9i0	183	8	involved	involve	VBN
cord-104223-ht3ry9i0	183	9	in	in	IN
cord-104223-ht3ry9i0	183	10	the	the	DT
cord-104223-ht3ry9i0	183	11	budding	budding	NN
cord-104223-ht3ry9i0	183	12	of	of	IN
cord-104223-ht3ry9i0	183	13	regulated	regulated	JJ
cord-104223-ht3ry9i0	183	14	secretory	secretory	JJ
cord-104223-ht3ry9i0	183	15	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	183	16	(	(	-LRB-
cord-104223-ht3ry9i0	184	1	Orci	Orci	NNP
cord-104223-ht3ry9i0	184	2	et	et	NNP
cord-104223-ht3ry9i0	184	3	al	al	NNP
cord-104223-ht3ry9i0	184	4	.	.	.
cord-104223-ht3ry9i0	185	1	,	,	,
cord-104223-ht3ry9i0	185	2	1984	1984	CD
cord-104223-ht3ry9i0	185	3	(	(	-LRB-
cord-104223-ht3ry9i0	185	4	Orci	Orci	NNP
cord-104223-ht3ry9i0	185	5	et	et	NNP
cord-104223-ht3ry9i0	185	6	al	al	NNP
cord-104223-ht3ry9i0	185	7	.	.	NNP
cord-104223-ht3ry9i0	185	8	,	,	,
cord-104223-ht3ry9i0	185	9	,	,	,
cord-104223-ht3ry9i0	185	10	1987	1987	CD
cord-104223-ht3ry9i0	185	11	or	or	CC
cord-104223-ht3ry9i0	185	12	recycling	recycling	NN
cord-104223-ht3ry9i0	185	13	of	of	IN
cord-104223-ht3ry9i0	185	14	protein	protein	NN
cord-104223-ht3ry9i0	185	15	from	from	IN
cord-104223-ht3ry9i0	185	16	immature	immature	JJ
cord-104223-ht3ry9i0	185	17	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	185	18	to	to	IN
cord-104223-ht3ry9i0	185	19	the	the	DT
cord-104223-ht3ry9i0	185	20	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	185	21	apparatus	apparatus	NN
cord-104223-ht3ry9i0	185	22	(	(	-LRB-
cord-104223-ht3ry9i0	185	23	Tooze	Tooze	NNP
cord-104223-ht3ry9i0	185	24	and	and	CC
cord-104223-ht3ry9i0	185	25	Tooze	Tooze	NNP
cord-104223-ht3ry9i0	185	26	,	,	,
cord-104223-ht3ry9i0	185	27	1986	1986	CD
cord-104223-ht3ry9i0	185	28	)	)	-RRB-
cord-104223-ht3ry9i0	185	29	.	.	.
cord-104223-ht3ry9i0	186	1	Lysosomal	Lysosomal	NNP
cord-104223-ht3ry9i0	186	2	enzymes	enzyme	NNS
cord-104223-ht3ry9i0	186	3	are	be	VBP
cord-104223-ht3ry9i0	186	4	most	most	RBS
cord-104223-ht3ry9i0	186	5	probably	probably	RB
cord-104223-ht3ry9i0	186	6	removed	remove	VBN
cord-104223-ht3ry9i0	186	7	via	via	IN
cord-104223-ht3ry9i0	186	8	clathrin	clathrin	NN
cord-104223-ht3ry9i0	186	9	-	-	HYPH
cord-104223-ht3ry9i0	186	10	coated	coat	VBN
cord-104223-ht3ry9i0	186	11	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	186	12	from	from	IN
cord-104223-ht3ry9i0	186	13	the	the	DT
cord-104223-ht3ry9i0	186	14	TGN	TGN	NNP
cord-104223-ht3ry9i0	186	15	(	(	-LRB-
cord-104223-ht3ry9i0	186	16	Campbell	Campbell	NNP
cord-104223-ht3ry9i0	186	17	and	and	CC
cord-104223-ht3ry9i0	186	18	Rome	Rome	NNP
cord-104223-ht3ry9i0	186	19	,	,	,
cord-104223-ht3ry9i0	186	20	1983	1983	CD
cord-104223-ht3ry9i0	186	21	;	;	:
cord-104223-ht3ry9i0	186	22	Grifliths	Grifliths	NNP
cord-104223-ht3ry9i0	186	23	and	and	CC
cord-104223-ht3ry9i0	186	24	Simons	Simons	NNP
cord-104223-ht3ry9i0	186	25	,	,	,
cord-104223-ht3ry9i0	186	26	1986	1986	CD
cord-104223-ht3ry9i0	186	27	;	;	:
cord-104223-ht3ry9i0	186	28	von	von	NNP
cord-104223-ht3ry9i0	186	29	Figura	Figura	NNP
cord-104223-ht3ry9i0	186	30	and	and	CC
cord-104223-ht3ry9i0	186	31	Hasilik	Hasilik	NNP
cord-104223-ht3ry9i0	186	32	,	,	,
cord-104223-ht3ry9i0	186	33	1986	1986	CD
cord-104223-ht3ry9i0	186	34	)	)	-RRB-
cord-104223-ht3ry9i0	186	35	,	,	,
cord-104223-ht3ry9i0	186	36	suggesting	suggest	VBG
cord-104223-ht3ry9i0	186	37	that	that	IN
cord-104223-ht3ry9i0	186	38	the	the	DT
cord-104223-ht3ry9i0	186	39	function	function	NN
cord-104223-ht3ry9i0	186	40	of	of	IN
cord-104223-ht3ry9i0	186	41	clathrin	clathrin	NN
cord-104223-ht3ry9i0	186	42	patches	patch	NNS
cord-104223-ht3ry9i0	186	43	on	on	IN
cord-104223-ht3ry9i0	186	44	immature	immature	JJ
cord-104223-ht3ry9i0	186	45	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	186	46	may	may	MD
cord-104223-ht3ry9i0	186	47	be	be	VB
cord-104223-ht3ry9i0	186	48	to	to	TO
cord-104223-ht3ry9i0	186	49	facilitate	facilitate	VB
cord-104223-ht3ry9i0	186	50	sorting	sorting	NN
cord-104223-ht3ry9i0	186	51	of	of	IN
cord-104223-ht3ry9i0	186	52	lysosomal	lysosomal	JJ
cord-104223-ht3ry9i0	186	53	proteins	protein	NNS
cord-104223-ht3ry9i0	186	54	.	.	.
cord-104223-ht3ry9i0	187	1	The	the	DT
cord-104223-ht3ry9i0	187	2	above	above	JJ
cord-104223-ht3ry9i0	187	3	results	result	NNS
cord-104223-ht3ry9i0	187	4	suggest	suggest	VBP
cord-104223-ht3ry9i0	187	5	that	that	IN
cord-104223-ht3ry9i0	187	6	sorting	sorting	NN
cord-104223-ht3ry9i0	187	7	occurs	occur	VBZ
cord-104223-ht3ry9i0	187	8	as	as	IN
cord-104223-ht3ry9i0	187	9	the	the	DT
cord-104223-ht3ry9i0	187	10	aminoterminal	aminoterminal	JJ
cord-104223-ht3ry9i0	187	11	intermediate	intermediate	JJ
cord-104223-ht3ry9i0	187	12	moves	move	NNS
cord-104223-ht3ry9i0	187	13	from	from	IN
cord-104223-ht3ry9i0	187	14	small	small	JJ
cord-104223-ht3ry9i0	187	15	immature	immature	JJ
cord-104223-ht3ry9i0	187	16	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	187	17	and	and	CC
cord-104223-ht3ry9i0	187	18	clear	clear	JJ
cord-104223-ht3ry9i0	187	19	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	187	20	to	to	IN
cord-104223-ht3ry9i0	187	21	large	large	JJ
cord-104223-ht3ry9i0	187	22	immature	immature	JJ
cord-104223-ht3ry9i0	187	23	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	187	24	,	,	,
cord-104223-ht3ry9i0	187	25	all	all	DT
cord-104223-ht3ry9i0	187	26	of	of	IN
cord-104223-ht3ry9i0	187	27	which	which	WDT
cord-104223-ht3ry9i0	187	28	are	be	VBP
cord-104223-ht3ry9i0	187	29	defined	define	VBN
cord-104223-ht3ry9i0	187	30	by	by	IN
cord-104223-ht3ry9i0	187	31	acid	acid	NN
cord-104223-ht3ry9i0	187	32	phosphatase	phosphatase	NN
cord-104223-ht3ry9i0	187	33	cytochemistry	cytochemistry	NN
cord-104223-ht3ry9i0	187	34	as	as	IN
cord-104223-ht3ry9i0	187	35	part	part	NN
cord-104223-ht3ry9i0	187	36	of	of	IN
cord-104223-ht3ry9i0	187	37	the	the	DT
cord-104223-ht3ry9i0	187	38	TGN	TGN	NNP
cord-104223-ht3ry9i0	187	39	.	.	.
cord-104223-ht3ry9i0	188	1	Furthermore	furthermore	RB
cord-104223-ht3ry9i0	188	2	,	,	,
cord-104223-ht3ry9i0	188	3	we	-PRON-	PRP
cord-104223-ht3ry9i0	188	4	have	have	VBP
cord-104223-ht3ry9i0	188	5	demonstrated	demonstrate	VBN
cord-104223-ht3ry9i0	188	6	the	the	DT
cord-104223-ht3ry9i0	188	7	site	site	NN
cord-104223-ht3ry9i0	188	8	ofprohormone	ofprohormone	NN
cord-104223-ht3ry9i0	188	9	cleavage	cleavage	NN
cord-104223-ht3ry9i0	188	10	to	to	TO
cord-104223-ht3ry9i0	188	11	be	be	VB
cord-104223-ht3ry9i0	188	12	the	the	DT
cord-104223-ht3ry9i0	188	13	clear	clear	JJ
cord-104223-ht3ry9i0	188	14	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	188	15	,	,	,
cord-104223-ht3ry9i0	188	16	small	small	JJ
cord-104223-ht3ry9i0	188	17	immature	immature	JJ
cord-104223-ht3ry9i0	188	18	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	188	19	,	,	,
cord-104223-ht3ry9i0	188	20	or	or	CC
cord-104223-ht3ry9i0	188	21	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	188	22	stacks	stack	NNS
cord-104223-ht3ry9i0	188	23	.	.	.
cord-104223-ht3ry9i0	189	1	Yet	yet	RB
cord-104223-ht3ry9i0	189	2	,	,	,
cord-104223-ht3ry9i0	189	3	at	at	IN
cord-104223-ht3ry9i0	189	4	a	a	DT
cord-104223-ht3ry9i0	189	5	time	time	NN
cord-104223-ht3ry9i0	189	6	when	when	WRB
cord-104223-ht3ry9i0	189	7	the	the	DT
cord-104223-ht3ry9i0	189	8	prohormone	prohormone	NN
cord-104223-ht3ry9i0	189	9	is	be	VBZ
cord-104223-ht3ry9i0	189	10	intact	intact	JJ
cord-104223-ht3ry9i0	189	11	(	(	-LRB-
cord-104223-ht3ry9i0	189	12	30-min	30-min	CD
cord-104223-ht3ry9i0	189	13	pulse	pulse	NN
cord-104223-ht3ry9i0	189	14	;	;	:
cord-104223-ht3ry9i0	189	15	Fig	fig	NN
cord-104223-ht3ry9i0	189	16	.	.	NNP
cord-104223-ht3ry9i0	189	17	2	2	CD
cord-104223-ht3ry9i0	189	18	B	b	NN
cord-104223-ht3ry9i0	189	19	)	)	-RRB-
cord-104223-ht3ry9i0	189	20	,	,	,
cord-104223-ht3ry9i0	189	21	counts	count	NNS
cord-104223-ht3ry9i0	189	22	are	be	VBP
cord-104223-ht3ry9i0	189	23	located	locate	VBN
cord-104223-ht3ry9i0	189	24	within	within	IN
cord-104223-ht3ry9i0	189	25	the	the	DT
cord-104223-ht3ry9i0	189	26	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	189	27	stacks	stack	NNS
cord-104223-ht3ry9i0	189	28	(	(	-LRB-
cord-104223-ht3ry9i0	189	29	Fig	fig	NN
cord-104223-ht3ry9i0	189	30	.	.	.
cord-104223-ht3ry9i0	189	31	3	3	CD
cord-104223-ht3ry9i0	189	32	A	a	NN
cord-104223-ht3ry9i0	189	33	)	)	-RRB-
cord-104223-ht3ry9i0	189	34	,	,	,
cord-104223-ht3ry9i0	189	35	suggesting	suggest	VBG
cord-104223-ht3ry9i0	189	36	that	that	IN
cord-104223-ht3ry9i0	189	37	the	the	DT
cord-104223-ht3ry9i0	189	38	cleavage	cleavage	NN
cord-104223-ht3ry9i0	189	39	of	of	IN
cord-104223-ht3ry9i0	189	40	the	the	DT
cord-104223-ht3ry9i0	189	41	prohormone	prohormone	NN
cord-104223-ht3ry9i0	189	42	must	must	MD
cord-104223-ht3ry9i0	189	43	occur	occur	VB
cord-104223-ht3ry9i0	189	44	after	after	IN
cord-104223-ht3ry9i0	189	45	this	this	DT
cord-104223-ht3ry9i0	189	46	point	point	NN
cord-104223-ht3ry9i0	189	47	,	,	,
cord-104223-ht3ry9i0	189	48	either	either	CC
cord-104223-ht3ry9i0	189	49	in	in	IN
cord-104223-ht3ry9i0	189	50	a	a	DT
cord-104223-ht3ry9i0	189	51	late	late	JJ
cord-104223-ht3ry9i0	189	52	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	189	53	stack	stack	NN
cord-104223-ht3ry9i0	189	54	or	or	CC
cord-104223-ht3ry9i0	189	55	,	,	,
cord-104223-ht3ry9i0	189	56	more	more	RBR
cord-104223-ht3ry9i0	189	57	likely	likely	JJ
cord-104223-ht3ry9i0	189	58	,	,	,
cord-104223-ht3ry9i0	189	59	the	the	DT
cord-104223-ht3ry9i0	189	60	TGN	TGN	NNP
cord-104223-ht3ry9i0	189	61	.	.	.
cord-104223-ht3ry9i0	190	1	(	(	-LRB-
cord-104223-ht3ry9i0	190	2	Table	table	NN
cord-104223-ht3ry9i0	190	3	I	-PRON-	PRP
cord-104223-ht3ry9i0	190	4	)	)	-RRB-
cord-104223-ht3ry9i0	190	5	 	 	_SP
cord-104223-ht3ry9i0	190	6	Quantitative	Quantitative	NNP
cord-104223-ht3ry9i0	190	7	HPLC	HPLC	NNP
cord-104223-ht3ry9i0	190	8	studies	study	NNS
cord-104223-ht3ry9i0	190	9	indicate	indicate	VBP
cord-104223-ht3ry9i0	190	10	that	that	IN
cord-104223-ht3ry9i0	190	11	the	the	DT
cord-104223-ht3ry9i0	190	12	carboxyterminal	carboxyterminal	NNP
cord-104223-ht3ry9i0	190	13	(	(	-LRB-
cord-104223-ht3ry9i0	190	14	Ile	Ile	NNP
cord-104223-ht3ry9i0	190	15	)	)	-RRB-
cord-104223-ht3ry9i0	190	16	final	final	JJ
cord-104223-ht3ry9i0	190	17	product	product	NN
cord-104223-ht3ry9i0	190	18	peptides	peptide	NNS
cord-104223-ht3ry9i0	190	19	are	be	VBP
cord-104223-ht3ry9i0	190	20	present	present	JJ
cord-104223-ht3ry9i0	190	21	at	at	IN
cord-104223-ht3ry9i0	190	22	three	three	CD
cord-104223-ht3ry9i0	190	23	-	-	HYPH
cord-104223-ht3ry9i0	190	24	to	to	IN
cord-104223-ht3ry9i0	190	25	eightfold	eightfold	VB
cord-104223-ht3ry9i0	190	26	higher	high	JJR
cord-104223-ht3ry9i0	190	27	steady	steady	JJ
cord-104223-ht3ry9i0	190	28	-	-	HYPH
cord-104223-ht3ry9i0	190	29	state	state	NN
cord-104223-ht3ry9i0	190	30	levels	level	NNS
cord-104223-ht3ry9i0	190	31	than	than	IN
cord-104223-ht3ry9i0	190	32	the	the	DT
cord-104223-ht3ry9i0	190	33	amino	amino	NN
cord-104223-ht3ry9i0	190	34	-	-	HYPH
cord-104223-ht3ry9i0	190	35	terminal	terminal	NN
cord-104223-ht3ry9i0	190	36	(	(	-LRB-
cord-104223-ht3ry9i0	190	37	Phe	Phe	NNP
cord-104223-ht3ry9i0	190	38	)	)	-RRB-
cord-104223-ht3ry9i0	190	39	final	final	JJ
cord-104223-ht3ry9i0	190	40	peptides	peptide	NNS
cord-104223-ht3ry9i0	190	41	(	(	-LRB-
cord-104223-ht3ry9i0	190	42	Fig	Fig	NNP
cord-104223-ht3ry9i0	190	43	.	.	NNP
cord-104223-ht3ry9i0	190	44	1	1	CD
cord-104223-ht3ry9i0	190	45	;	;	:
cord-104223-ht3ry9i0	190	46	Fisher	Fisher	NNP
cord-104223-ht3ry9i0	190	47	et	et	NNP
cord-104223-ht3ry9i0	190	48	al	al	NNP
cord-104223-ht3ry9i0	190	49	.	.	NNP
cord-104223-ht3ry9i0	190	50	,	,	,
cord-104223-ht3ry9i0	190	51	1988	1988	CD
cord-104223-ht3ry9i0	190	52	)	)	-RRB-
cord-104223-ht3ry9i0	190	53	.	.	.
cord-104223-ht3ry9i0	191	1	The	the	DT
cord-104223-ht3ry9i0	191	2	large	large	JJ
cord-104223-ht3ry9i0	191	3	DCVs	dcv	NNS
cord-104223-ht3ry9i0	191	4	are	be	VBP
cord-104223-ht3ry9i0	191	5	not	not	RB
cord-104223-ht3ry9i0	191	6	transported	transport	VBN
cord-104223-ht3ry9i0	191	7	to	to	IN
cord-104223-ht3ry9i0	191	8	the	the	DT
cord-104223-ht3ry9i0	191	9	processes	process	NNS
cord-104223-ht3ry9i0	192	1	(	(	-LRB-
cord-104223-ht3ry9i0	192	2	Kreiner	Kreiner	NNP
cord-104223-ht3ry9i0	192	3	et	et	NNP
cord-104223-ht3ry9i0	192	4	al	al	NNP
cord-104223-ht3ry9i0	192	5	.	.	NNP
cord-104223-ht3ry9i0	192	6	,	,	,
cord-104223-ht3ry9i0	192	7	1986	1986	CD
cord-104223-ht3ry9i0	192	8	)	)	-RRB-
cord-104223-ht3ry9i0	192	9	and	and	CC
cord-104223-ht3ry9i0	193	1	quantitative	quantitative	NNP
cord-104223-ht3ry9i0	193	2	immunoelectron	immunoelectron	NNP
cord-104223-ht3ry9i0	193	3	microscopy	microscopy	NNP
cord-104223-ht3ry9i0	193	4	Studies	study	NNS
cord-104223-ht3ry9i0	193	5	suggest	suggest	VBP
cord-104223-ht3ry9i0	193	6	that	that	IN
cord-104223-ht3ry9i0	193	7	the	the	DT
cord-104223-ht3ry9i0	193	8	different	different	JJ
cord-104223-ht3ry9i0	193	9	levels	level	NNS
cord-104223-ht3ry9i0	193	10	of	of	IN
cord-104223-ht3ry9i0	193	11	peptides	peptide	NNS
cord-104223-ht3ry9i0	193	12	could	could	MD
cord-104223-ht3ry9i0	193	13	be	be	VB
cord-104223-ht3ry9i0	193	14	due	due	JJ
cord-104223-ht3ry9i0	193	15	to	to	IN
cord-104223-ht3ry9i0	193	16	the	the	DT
cord-104223-ht3ry9i0	193	17	selective	selective	JJ
cord-104223-ht3ry9i0	193	18	degradation	degradation	NN
cord-104223-ht3ry9i0	193	19	or	or	CC
cord-104223-ht3ry9i0	193	20	release	release	NN
cord-104223-ht3ry9i0	193	21	of	of	IN
cord-104223-ht3ry9i0	193	22	these	these	DT
cord-104223-ht3ry9i0	193	23	large	large	JJ
cord-104223-ht3ry9i0	193	24	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	193	25	.	.	.
cord-104223-ht3ry9i0	194	1	To	to	TO
cord-104223-ht3ry9i0	194	2	examine	examine	VB
cord-104223-ht3ry9i0	194	3	this	this	DT
cord-104223-ht3ry9i0	194	4	question	question	NN
cord-104223-ht3ry9i0	194	5	we	-PRON-	PRP
cord-104223-ht3ry9i0	194	6	chased	chase	VBD
cord-104223-ht3ry9i0	194	7	[	[	-LRB-
cord-104223-ht3ry9i0	194	8	3H]Phe	3h]phe	CD
cord-104223-ht3ry9i0	194	9	-	-	HYPH
cord-104223-ht3ry9i0	194	10	labeled	label	VBN
cord-104223-ht3ry9i0	194	11	bag	bag	NN
cord-104223-ht3ry9i0	194	12	cell	cell	NN
cord-104223-ht3ry9i0	194	13	clusters	cluster	NNS
cord-104223-ht3ry9i0	194	14	for	for	IN
cord-104223-ht3ry9i0	194	15	longer	long	JJR
cord-104223-ht3ry9i0	194	16	times	time	NNS
cord-104223-ht3ry9i0	194	17	to	to	TO
cord-104223-ht3ry9i0	194	18	observe	observe	VB
cord-104223-ht3ry9i0	194	19	the	the	DT
cord-104223-ht3ry9i0	194	20	eventual	eventual	JJ
cord-104223-ht3ry9i0	194	21	fate	fate	NN
cord-104223-ht3ry9i0	194	22	of	of	IN
cord-104223-ht3ry9i0	194	23	the	the	DT
cord-104223-ht3ry9i0	194	24	large	large	JJ
cord-104223-ht3ry9i0	194	25	DCVs	dcv	NNS
cord-104223-ht3ry9i0	194	26	.	.	.
cord-104223-ht3ry9i0	195	1	After	after	IN
cord-104223-ht3ry9i0	195	2	12	12	CD
cord-104223-ht3ry9i0	195	3	h	h	NN
cord-104223-ht3ry9i0	195	4	of	of	IN
cord-104223-ht3ry9i0	195	5	chase	chase	NNP
cord-104223-ht3ry9i0	195	6	,	,	,
cord-104223-ht3ry9i0	195	7	many	many	JJ
cord-104223-ht3ry9i0	195	8	grains	grain	NNS
cord-104223-ht3ry9i0	195	9	are	be	VBP
cord-104223-ht3ry9i0	195	10	observed	observe	VBN
cord-104223-ht3ry9i0	195	11	in	in	IN
cord-104223-ht3ry9i0	195	12	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	195	13	with	with	IN
cord-104223-ht3ry9i0	195	14	heterogeneous	heterogeneous	JJ
cord-104223-ht3ry9i0	195	15	cores	core	NNS
cord-104223-ht3ry9i0	195	16	that	that	WDT
cord-104223-ht3ry9i0	195	17	we	-PRON-	PRP
cord-104223-ht3ry9i0	195	18	refer	refer	VBP
cord-104223-ht3ry9i0	195	19	to	to	IN
cord-104223-ht3ry9i0	195	20	as	as	RB
cord-104223-ht3ry9i0	195	21	mottled	mottled	JJ
cord-104223-ht3ry9i0	195	22	DCVs	dcv	NNS
cord-104223-ht3ry9i0	195	23	(	(	-LRB-
cord-104223-ht3ry9i0	195	24	Table	table	NN
cord-104223-ht3ry9i0	195	25	I	i	CD
cord-104223-ht3ry9i0	195	26	)	)	-RRB-
cord-104223-ht3ry9i0	195	27	.	.	.
cord-104223-ht3ry9i0	196	1	The	the	DT
cord-104223-ht3ry9i0	196	2	appearance	appearance	NN
cord-104223-ht3ry9i0	196	3	of	of	IN
cord-104223-ht3ry9i0	196	4	the	the	DT
cord-104223-ht3ry9i0	196	5	core	core	NN
cord-104223-ht3ry9i0	196	6	is	be	VBZ
cord-104223-ht3ry9i0	196	7	quite	quite	RB
cord-104223-ht3ry9i0	196	8	variable	variable	JJ
cord-104223-ht3ry9i0	196	9	,	,	,
cord-104223-ht3ry9i0	196	10	ranging	range	VBG
cord-104223-ht3ry9i0	196	11	from	from	IN
cord-104223-ht3ry9i0	196	12	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	196	13	that	that	WDT
cord-104223-ht3ry9i0	196	14	are	be	VBP
cord-104223-ht3ry9i0	196	15	mostly	mostly	RB
cord-104223-ht3ry9i0	196	16	clear	clear	JJ
cord-104223-ht3ry9i0	196	17	but	but	CC
cord-104223-ht3ry9i0	196	18	contained	contain	VBD
cord-104223-ht3ry9i0	196	19	patches	patch	NNS
cord-104223-ht3ry9i0	196	20	of	of	IN
cord-104223-ht3ry9i0	196	21	dense	dense	JJ
cord-104223-ht3ry9i0	196	22	material	material	NN
cord-104223-ht3ry9i0	196	23	(	(	-LRB-
cord-104223-ht3ry9i0	196	24	Fig.7	fig.7	IN
cord-104223-ht3ry9i0	196	25	A	a	NN
cord-104223-ht3ry9i0	196	26	)	)	-RRB-
cord-104223-ht3ry9i0	196	27	to	to	IN
cord-104223-ht3ry9i0	196	28	dense	dense	JJ
cord-104223-ht3ry9i0	196	29	DCVs	dcv	NNS
cord-104223-ht3ry9i0	196	30	with	with	IN
cord-104223-ht3ry9i0	196	31	nonhomogeneous	nonhomogeneous	JJ
cord-104223-ht3ry9i0	196	32	patches	patch	NNS
cord-104223-ht3ry9i0	196	33	(	(	-LRB-
cord-104223-ht3ry9i0	196	34	Fig	fig	NN
cord-104223-ht3ry9i0	196	35	.	.	.
cord-104223-ht3ry9i0	196	36	 	 	_SP
cord-104223-ht3ry9i0	197	1	7	7	CD
cord-104223-ht3ry9i0	197	2	B	b	NN
cord-104223-ht3ry9i0	197	3	)	)	-RRB-
cord-104223-ht3ry9i0	197	4	.	.	.
cord-104223-ht3ry9i0	198	1	Loss	loss	NN
cord-104223-ht3ry9i0	198	2	of	of	IN
cord-104223-ht3ry9i0	198	3	the	the	DT
cord-104223-ht3ry9i0	198	4	homogeneous	homogeneous	JJ
cord-104223-ht3ry9i0	198	5	dense	dense	JJ
cord-104223-ht3ry9i0	198	6	core	core	NN
cord-104223-ht3ry9i0	198	7	suggests	suggest	VBZ
cord-104223-ht3ry9i0	198	8	the	the	DT
cord-104223-ht3ry9i0	198	9	peptides	peptide	NNS
cord-104223-ht3ry9i0	198	10	are	be	VBP
cord-104223-ht3ry9i0	198	11	being	be	VBG
cord-104223-ht3ry9i0	198	12	degraded	degrade	VBN
cord-104223-ht3ry9i0	198	13	.	.	.
cord-104223-ht3ry9i0	199	1	Few	few	JJ
cord-104223-ht3ry9i0	199	2	grains	grain	NNS
cord-104223-ht3ry9i0	199	3	are	be	VBP
cord-104223-ht3ry9i0	199	4	observed	observe	VBN
cord-104223-ht3ry9i0	199	5	over	over	IN
cord-104223-ht3ry9i0	199	6	large	large	JJ
cord-104223-ht3ry9i0	199	7	membranous	membranous	JJ
cord-104223-ht3ry9i0	199	8	lysosomes	lysosome	NNS
cord-104223-ht3ry9i0	199	9	or	or	CC
cord-104223-ht3ry9i0	199	10	multivesicular	multivesicular	JJ
cord-104223-ht3ry9i0	199	11	bodies	body	NNS
cord-104223-ht3ry9i0	199	12	.	.	.
cord-104223-ht3ry9i0	200	1	Other	other	JJ
cord-104223-ht3ry9i0	200	2	interesting	interesting	JJ
cord-104223-ht3ry9i0	200	3	results	result	NNS
cord-104223-ht3ry9i0	200	4	from	from	IN
cord-104223-ht3ry9i0	200	5	this	this	DT
cord-104223-ht3ry9i0	200	6	time	time	NN
cord-104223-ht3ry9i0	200	7	point	point	NN
cord-104223-ht3ry9i0	200	8	include	include	VBP
cord-104223-ht3ry9i0	200	9	the	the	DT
cord-104223-ht3ry9i0	200	10	movement	movement	NN
cord-104223-ht3ry9i0	200	11	of	of	IN
cord-104223-ht3ry9i0	200	12	grains	grain	NNS
cord-104223-ht3ry9i0	200	13	from	from	IN
cord-104223-ht3ry9i0	200	14	immature	immature	JJ
cord-104223-ht3ry9i0	200	15	to	to	TO
cord-104223-ht3ry9i0	200	16	mature	mature	VB
cord-104223-ht3ry9i0	200	17	large	large	JJ
cord-104223-ht3ry9i0	200	18	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	200	19	and	and	CC
cord-104223-ht3ry9i0	200	20	an	an	DT
cord-104223-ht3ry9i0	200	21	increase	increase	NN
cord-104223-ht3ry9i0	200	22	in	in	IN
cord-104223-ht3ry9i0	200	23	the	the	DT
cord-104223-ht3ry9i0	200	24	number	number	NN
cord-104223-ht3ry9i0	200	25	of	of	IN
cord-104223-ht3ry9i0	200	26	grains	grain	NNS
cord-104223-ht3ry9i0	200	27	in	in	IN
cord-104223-ht3ry9i0	200	28	small	small	JJ
cord-104223-ht3ry9i0	200	29	mature	mature	JJ
cord-104223-ht3ry9i0	200	30	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	200	31	(	(	-LRB-
cord-104223-ht3ry9i0	200	32	Table	table	NN
cord-104223-ht3ry9i0	200	33	I	i	CD
cord-104223-ht3ry9i0	200	34	)	)	-RRB-
cord-104223-ht3ry9i0	200	35	.	.	.
cord-104223-ht3ry9i0	201	1	Coupled	couple	VBN
cord-104223-ht3ry9i0	201	2	with	with	IN
cord-104223-ht3ry9i0	201	3	the	the	DT
cord-104223-ht3ry9i0	201	4	lack	lack	NN
cord-104223-ht3ry9i0	201	5	of	of	IN
cord-104223-ht3ry9i0	201	6	constitutive	constitutive	JJ
cord-104223-ht3ry9i0	201	7	release	release	NN
cord-104223-ht3ry9i0	201	8	of	of	IN
cord-104223-ht3ry9i0	201	9	large	large	JJ
cord-104223-ht3ry9i0	201	10	vesicle	vesicle	NN
cord-104223-ht3ry9i0	201	11	contents	content	NNS
cord-104223-ht3ry9i0	201	12	(	(	-LRB-
cord-104223-ht3ry9i0	201	13	Fisher	Fisher	NNP
cord-104223-ht3ry9i0	201	14	,	,	,
cord-104223-ht3ry9i0	201	15	J.	J.	NNP
cord-104223-ht3ry9i0	201	16	,	,	,
cord-104223-ht3ry9i0	201	17	unpublished	unpublished	JJ
cord-104223-ht3ry9i0	201	18	data	datum	NNS
cord-104223-ht3ry9i0	201	19	)	)	-RRB-
cord-104223-ht3ry9i0	201	20	,	,	,
cord-104223-ht3ry9i0	201	21	these	these	DT
cord-104223-ht3ry9i0	201	22	results	result	NNS
cord-104223-ht3ry9i0	201	23	suggest	suggest	VBP
cord-104223-ht3ry9i0	201	24	that	that	IN
cord-104223-ht3ry9i0	201	25	the	the	DT
cord-104223-ht3ry9i0	201	26	asymmetry	asymmetry	NN
cord-104223-ht3ry9i0	201	27	in	in	IN
cord-104223-ht3ry9i0	201	28	peptide	peptide	JJ
cord-104223-ht3ry9i0	201	29	steady	steady	JJ
cord-104223-ht3ry9i0	201	30	-	-	HYPH
cord-104223-ht3ry9i0	201	31	state	state	NN
cord-104223-ht3ry9i0	201	32	levels	level	NNS
cord-104223-ht3ry9i0	201	33	is	be	VBZ
cord-104223-ht3ry9i0	201	34	generated	generate	VBN
cord-104223-ht3ry9i0	201	35	through	through	IN
cord-104223-ht3ry9i0	201	36	a	a	DT
cord-104223-ht3ry9i0	201	37	degradative	degradative	JJ
cord-104223-ht3ry9i0	201	38	pathway	pathway	NN
cord-104223-ht3ry9i0	201	39	.	.	.
cord-104223-ht3ry9i0	202	1	Our	-PRON-	PRP$
cord-104223-ht3ry9i0	202	2	results	result	NNS
cord-104223-ht3ry9i0	202	3	suggest	suggest	VBP
cord-104223-ht3ry9i0	202	4	a	a	DT
cord-104223-ht3ry9i0	202	5	model	model	NN
cord-104223-ht3ry9i0	202	6	for	for	IN
cord-104223-ht3ry9i0	202	7	sorting	sorting	NN
cord-104223-ht3ry9i0	202	8	within	within	IN
cord-104223-ht3ry9i0	202	9	the	the	DT
cord-104223-ht3ry9i0	202	10	regulated	regulate	VBN
cord-104223-ht3ry9i0	202	11	secretory	secretory	JJ
cord-104223-ht3ry9i0	202	12	pathway	pathway	NN
cord-104223-ht3ry9i0	202	13	(	(	-LRB-
cord-104223-ht3ry9i0	202	14	Fig	Fig	NNP
cord-104223-ht3ry9i0	202	15	.	.	.
cord-104223-ht3ry9i0	202	16	8)	8)	NNP
cord-104223-ht3ry9i0	202	17	.	.	.
cord-104223-ht3ry9i0	203	1	Correlating	correlate	VBG
cord-104223-ht3ry9i0	203	2	a	a	DT
cord-104223-ht3ry9i0	203	3	biochemical	biochemical	JJ
cord-104223-ht3ry9i0	203	4	assay	assay	NN
cord-104223-ht3ry9i0	203	5	of	of	IN
cord-104223-ht3ry9i0	203	6	processing	processing	NN
cord-104223-ht3ry9i0	203	7	with	with	IN
cord-104223-ht3ry9i0	203	8	EM	EM	NNP
cord-104223-ht3ry9i0	203	9	autoradiography	autoradiography	NNP
cord-104223-ht3ry9i0	203	10	predicts	predict	VBZ
cord-104223-ht3ry9i0	203	11	cleavage	cleavage	NN
cord-104223-ht3ry9i0	203	12	of	of	IN
cord-104223-ht3ry9i0	203	13	the	the	DT
cord-104223-ht3ry9i0	203	14	ELH	ELH	NNP
cord-104223-ht3ry9i0	203	15	prohormone	prohormone	NN
cord-104223-ht3ry9i0	203	16	in	in	IN
cord-104223-ht3ry9i0	203	17	a	a	DT
cord-104223-ht3ry9i0	203	18	late	late	JJ
cord-104223-ht3ry9i0	203	19	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	203	20	compartment	compartment	NN
cord-104223-ht3ry9i0	203	21	.	.	.
cord-104223-ht3ry9i0	204	1	Further	further	JJ
cord-104223-ht3ry9i0	204	2	support	support	NN
cord-104223-ht3ry9i0	204	3	for	for	IN
cord-104223-ht3ry9i0	204	4	this	this	DT
cord-104223-ht3ry9i0	204	5	model	model	NN
cord-104223-ht3ry9i0	204	6	comes	come	VBZ
cord-104223-ht3ry9i0	204	7	from	from	IN
cord-104223-ht3ry9i0	204	8	subcellular	subcellular	JJ
cord-104223-ht3ry9i0	204	9	fractionation	fractionation	NN
cord-104223-ht3ry9i0	204	10	studies	study	NNS
cord-104223-ht3ry9i0	204	11	of	of	IN
cord-104223-ht3ry9i0	204	12	bag	bag	NN
cord-104223-ht3ry9i0	204	13	cells	cell	NNS
cord-104223-ht3ry9i0	204	14	,	,	,
cord-104223-ht3ry9i0	204	15	where	where	WRB
cord-104223-ht3ry9i0	204	16	the	the	DT
cord-104223-ht3ry9i0	204	17	initial	initial	JJ
cord-104223-ht3ry9i0	204	18	cleavage	cleavage	NN
cord-104223-ht3ry9i0	204	19	is	be	VBZ
cord-104223-ht3ry9i0	204	20	shown	show	VBN
cord-104223-ht3ry9i0	204	21	to	to	TO
cord-104223-ht3ry9i0	204	22	occur	occur	VB
cord-104223-ht3ry9i0	204	23	in	in	IN
cord-104223-ht3ry9i0	204	24	a	a	DT
cord-104223-ht3ry9i0	204	25	light	light	JJ
cord-104223-ht3ry9i0	204	26	fraction	fraction	NN
cord-104223-ht3ry9i0	204	27	enriched	enrich	VBN
cord-104223-ht3ry9i0	204	28	in	in	IN
cord-104223-ht3ry9i0	204	29	mannosidase	mannosidase	NN
cord-104223-ht3ry9i0	204	30	II	ii	CD
cord-104223-ht3ry9i0	204	31	activity	activity	NN
cord-104223-ht3ry9i0	204	32	(	(	-LRB-
cord-104223-ht3ry9i0	204	33	a	a	DT
cord-104223-ht3ry9i0	204	34	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	204	35	marker	marker	NN
cord-104223-ht3ry9i0	204	36	)	)	-RRB-
cord-104223-ht3ry9i0	204	37	and	and	CC
cord-104223-ht3ry9i0	204	38	well	well	RB
cord-104223-ht3ry9i0	204	39	separated	separate	VBN
cord-104223-ht3ry9i0	204	40	from	from	IN
cord-104223-ht3ry9i0	204	41	the	the	DT
cord-104223-ht3ry9i0	204	42	DCVs	dcv	NNS
cord-104223-ht3ry9i0	204	43	(	(	-LRB-
cord-104223-ht3ry9i0	204	44	Sweet	Sweet	NNP
cord-104223-ht3ry9i0	204	45	,	,	,
cord-104223-ht3ry9i0	204	46	A.	a.	NN
cord-104223-ht3ry9i0	204	47	,	,	,
cord-104223-ht3ry9i0	204	48	J.	J.	NNP
cord-104223-ht3ry9i0	204	49	M.	M.	NNP
cord-104223-ht3ry9i0	204	50	Fisher	Fisher	NNP
cord-104223-ht3ry9i0	204	51	,	,	,
cord-104223-ht3ry9i0	204	52	W.	W.	NNP
cord-104223-ht3ry9i0	204	53	S.	S.	NNP
cord-104223-ht3ry9i0	204	54	Sossin	Sossin	NNP
cord-104223-ht3ry9i0	204	55	,	,	,
cord-104223-ht3ry9i0	204	56	R.	R.	NNP
cord-104223-ht3ry9i0	204	57	Newcomb	Newcomb	NNP
cord-104223-ht3ry9i0	204	58	,	,	,
cord-104223-ht3ry9i0	204	59	and	and	CC
cord-104223-ht3ry9i0	204	60	R.	R.	NNP
cord-104223-ht3ry9i0	204	61	H.	H.	NNP
cord-104223-ht3ry9i0	204	62	Scheller	Scheller	NNP
cord-104223-ht3ry9i0	204	63	,	,	,
cord-104223-ht3ry9i0	204	64	manuscript	manuscript	NN
cord-104223-ht3ry9i0	204	65	submitted	submit	VBN
cord-104223-ht3ry9i0	204	66	for	for	IN
cord-104223-ht3ry9i0	204	67	publication	publication	NN
cord-104223-ht3ry9i0	204	68	)	)	-RRB-
cord-104223-ht3ry9i0	204	69	.	.	.
cord-104223-ht3ry9i0	205	1	The	the	DT
cord-104223-ht3ry9i0	205	2	initial	initial	JJ
cord-104223-ht3ry9i0	205	3	cleavage	cleavage	NN
cord-104223-ht3ry9i0	205	4	is	be	VBZ
cord-104223-ht3ry9i0	205	5	not	not	RB
cord-104223-ht3ry9i0	205	6	blocked	block	VBN
cord-104223-ht3ry9i0	205	7	by	by	IN
cord-104223-ht3ry9i0	205	8	monensin	monensin	NNP
cord-104223-ht3ry9i0	205	9	,	,	,
cord-104223-ht3ry9i0	205	10	which	which	WDT
cord-104223-ht3ry9i0	205	11	does	do	VBZ
cord-104223-ht3ry9i0	205	12	block	block	VB
cord-104223-ht3ry9i0	205	13	the	the	DT
cord-104223-ht3ry9i0	205	14	formation	formation	NN
cord-104223-ht3ry9i0	205	15	of	of	IN
cord-104223-ht3ry9i0	205	16	mature	mature	JJ
cord-104223-ht3ry9i0	205	17	granules	granule	NNS
cord-104223-ht3ry9i0	205	18	.	.	.
cord-104223-ht3ry9i0	206	1	The	the	DT
cord-104223-ht3ry9i0	206	2	protease	protease	NN
cord-104223-ht3ry9i0	206	3	that	that	WDT
cord-104223-ht3ry9i0	206	4	cleaves	cleave	VBZ
cord-104223-ht3ry9i0	206	5	the	the	DT
cord-104223-ht3ry9i0	206	6	tetrabasic	tetrabasic	NN
cord-104223-ht3ry9i0	206	7	site	site	NN
cord-104223-ht3ry9i0	206	8	may	may	MD
cord-104223-ht3ry9i0	206	9	be	be	VB
cord-104223-ht3ry9i0	206	10	a	a	DT
cord-104223-ht3ry9i0	206	11	TGN	TGN	NNP
cord-104223-ht3ry9i0	206	12	resident	resident	NN
cord-104223-ht3ry9i0	206	13	protein	protein	NN
cord-104223-ht3ry9i0	206	14	whose	whose	WP$
cord-104223-ht3ry9i0	206	15	activity	activity	NN
cord-104223-ht3ry9i0	206	16	triggers	trigger	VBZ
cord-104223-ht3ry9i0	206	17	the	the	DT
cord-104223-ht3ry9i0	206	18	condensation	condensation	NN
cord-104223-ht3ry9i0	206	19	and	and	CC
cord-104223-ht3ry9i0	206	20	sorting	sorting	NN
cord-104223-ht3ry9i0	206	21	of	of	IN
cord-104223-ht3ry9i0	206	22	the	the	DT
cord-104223-ht3ry9i0	206	23	processing	processing	NN
cord-104223-ht3ry9i0	206	24	intermediates	intermediate	NNS
cord-104223-ht3ry9i0	206	25	in	in	IN
cord-104223-ht3ry9i0	206	26	this	this	DT
cord-104223-ht3ry9i0	206	27	compartment	compartment	NN
cord-104223-ht3ry9i0	206	28	.	.	.
cord-104223-ht3ry9i0	207	1	Alternatively	alternatively	RB
cord-104223-ht3ry9i0	207	2	,	,	,
cord-104223-ht3ry9i0	207	3	processing	processing	NN
cord-104223-ht3ry9i0	207	4	enzymes	enzyme	NNS
cord-104223-ht3ry9i0	207	5	with	with	IN
cord-104223-ht3ry9i0	207	6	different	different	JJ
cord-104223-ht3ry9i0	207	7	pH	pH	NNP
cord-104223-ht3ry9i0	207	8	activation	activation	NN
cord-104223-ht3ry9i0	207	9	profiles	profile	NNS
cord-104223-ht3ry9i0	207	10	or	or	CC
cord-104223-ht3ry9i0	207	11	different	different	JJ
cord-104223-ht3ry9i0	207	12	affinities	affinity	NNS
cord-104223-ht3ry9i0	207	13	for	for	IN
cord-104223-ht3ry9i0	207	14	the	the	DT
cord-104223-ht3ry9i0	207	15	various	various	JJ
cord-104223-ht3ry9i0	207	16	cleavage	cleavage	NN
cord-104223-ht3ry9i0	207	17	sites	site	NNS
cord-104223-ht3ry9i0	207	18	may	may	MD
cord-104223-ht3ry9i0	207	19	explain	explain	VB
cord-104223-ht3ry9i0	207	20	the	the	DT
cord-104223-ht3ry9i0	207	21	distinct	distinct	JJ
cord-104223-ht3ry9i0	207	22	subcellular	subcellular	JJ
cord-104223-ht3ry9i0	207	23	sites	site	NNS
cord-104223-ht3ry9i0	207	24	of	of	IN
cord-104223-ht3ry9i0	207	25	endoproteolytic	endoproteolytic	JJ
cord-104223-ht3ry9i0	207	26	cleavage	cleavage	NN
cord-104223-ht3ry9i0	207	27	in	in	IN
cord-104223-ht3ry9i0	207	28	the	the	DT
cord-104223-ht3ry9i0	207	29	bag	bag	NN
cord-104223-ht3ry9i0	207	30	cells	cell	NNS
cord-104223-ht3ry9i0	207	31	.	.	.
cord-104223-ht3ry9i0	208	1	Multiple	multiple	JJ
cord-104223-ht3ry9i0	208	2	enzymes	enzyme	NNS
cord-104223-ht3ry9i0	208	3	with	with	IN
cord-104223-ht3ry9i0	208	4	different	different	JJ
cord-104223-ht3ry9i0	208	5	pH	ph	NN
cord-104223-ht3ry9i0	208	6	profiles	profile	NNS
cord-104223-ht3ry9i0	208	7	have	have	VBP
cord-104223-ht3ry9i0	208	8	been	be	VBN
cord-104223-ht3ry9i0	208	9	proposed	propose	VBN
cord-104223-ht3ry9i0	208	10	to	to	TO
cord-104223-ht3ry9i0	208	11	differentiate	differentiate	VB
cord-104223-ht3ry9i0	208	12	between	between	IN
cord-104223-ht3ry9i0	208	13	the	the	DT
cord-104223-ht3ry9i0	208	14	two	two	CD
cord-104223-ht3ry9i0	208	15	cleavages	cleavage	NNS
cord-104223-ht3ry9i0	208	16	of	of	IN
cord-104223-ht3ry9i0	208	17	the	the	DT
cord-104223-ht3ry9i0	208	18	insulin	insulin	NN
cord-104223-ht3ry9i0	208	19	precursor	precursor	NN
cord-104223-ht3ry9i0	208	20	(	(	-LRB-
cord-104223-ht3ry9i0	208	21	Davidson	Davidson	NNP
cord-104223-ht3ry9i0	208	22	et	et	FW
cord-104223-ht3ry9i0	208	23	al	al	NNP
cord-104223-ht3ry9i0	208	24	.	.	NNP
cord-104223-ht3ry9i0	208	25	,	,	,
cord-104223-ht3ry9i0	208	26	1988	1988	CD
cord-104223-ht3ry9i0	208	27	)	)	-RRB-
cord-104223-ht3ry9i0	208	28	.	.	.
cord-104223-ht3ry9i0	209	1	After	after	IN
cord-104223-ht3ry9i0	209	2	the	the	DT
cord-104223-ht3ry9i0	209	3	initial	initial	JJ
cord-104223-ht3ry9i0	209	4	cleavage	cleavage	NN
cord-104223-ht3ry9i0	209	5	event	event	NN
cord-104223-ht3ry9i0	209	6	,	,	,
cord-104223-ht3ry9i0	209	7	the	the	DT
cord-104223-ht3ry9i0	209	8	ELH	ELH	NNP
cord-104223-ht3ry9i0	209	9	-	-	HYPH
cord-104223-ht3ry9i0	209	10	containing	contain	VBG
cord-104223-ht3ry9i0	209	11	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	209	12	-	-	HYPH
cord-104223-ht3ry9i0	209	13	terminal	terminal	NN
cord-104223-ht3ry9i0	209	14	intermediate	intermediate	NN
cord-104223-ht3ry9i0	209	15	condenses	condense	VBZ
cord-104223-ht3ry9i0	209	16	in	in	IN
cord-104223-ht3ry9i0	209	17	one	one	CD
cord-104223-ht3ry9i0	209	18	region	region	NN
cord-104223-ht3ry9i0	209	19	of	of	IN
cord-104223-ht3ry9i0	209	20	the	the	DT
cord-104223-ht3ry9i0	209	21	TGN	TGN	NNP
cord-104223-ht3ry9i0	209	22	(	(	-LRB-
cord-104223-ht3ry9i0	209	23	small	small	JJ
cord-104223-ht3ry9i0	209	24	immature	immature	JJ
cord-104223-ht3ry9i0	209	25	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	209	26	)	)	-RRB-
cord-104223-ht3ry9i0	209	27	and	and	CC
cord-104223-ht3ry9i0	209	28	the	the	DT
cord-104223-ht3ry9i0	209	29	amino	amino	NN
cord-104223-ht3ry9i0	209	30	-	-	HYPH
cord-104223-ht3ry9i0	209	31	terminal	terminal	NN
cord-104223-ht3ry9i0	209	32	bag	bag	NN
cord-104223-ht3ry9i0	209	33	cell	cell	NN
cord-104223-ht3ry9i0	209	34	peptide	peptide	NN
cord-104223-ht3ry9i0	209	35	-	-	HYPH
cord-104223-ht3ry9i0	209	36	containing	contain	VBG
cord-104223-ht3ry9i0	209	37	intermediate	intermediate	JJ
cord-104223-ht3ry9i0	209	38	condenses	condense	VBZ
cord-104223-ht3ry9i0	209	39	in	in	IN
cord-104223-ht3ry9i0	209	40	another	another	DT
cord-104223-ht3ry9i0	209	41	region	region	NN
cord-104223-ht3ry9i0	209	42	of	of	IN
cord-104223-ht3ry9i0	209	43	the	the	DT
cord-104223-ht3ry9i0	209	44	TGN	TGN	NNP
cord-104223-ht3ry9i0	209	45	(	(	-LRB-
cord-104223-ht3ry9i0	209	46	large	large	JJ
cord-104223-ht3ry9i0	209	47	immature	immature	JJ
cord-104223-ht3ry9i0	209	48	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	209	49	)	)	-RRB-
cord-104223-ht3ry9i0	209	50	.	.	.
cord-104223-ht3ry9i0	210	1	This	this	DT
cord-104223-ht3ry9i0	210	2	model	model	NN
cord-104223-ht3ry9i0	210	3	is	be	VBZ
cord-104223-ht3ry9i0	210	4	consistent	consistent	JJ
cord-104223-ht3ry9i0	210	5	with	with	IN
cord-104223-ht3ry9i0	210	6	immunocytochemical	immunocytochemical	JJ
cord-104223-ht3ry9i0	210	7	studies	study	NNS
cord-104223-ht3ry9i0	210	8	that	that	WDT
cord-104223-ht3ry9i0	210	9	demonstrate	demonstrate	VBP
cord-104223-ht3ry9i0	210	10	that	that	IN
cord-104223-ht3ry9i0	210	11	small	small	JJ
cord-104223-ht3ry9i0	210	12	immature	immature	JJ
cord-104223-ht3ry9i0	210	13	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	210	14	connected	connect	VBN
cord-104223-ht3ry9i0	210	15	to	to	IN
cord-104223-ht3ry9i0	210	16	the	the	DT
cord-104223-ht3ry9i0	210	17	TGN	TGN	NNP
cord-104223-ht3ry9i0	210	18	contain	contain	VBP
cord-104223-ht3ry9i0	210	19	largely	largely	RB
cord-104223-ht3ry9i0	210	20	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	210	21	-	-	HYPH
cord-104223-ht3ry9i0	210	22	terminal	terminal	NN
cord-104223-ht3ry9i0	210	23	immunoreactivity	immunoreactivity	NN
cord-104223-ht3ry9i0	210	24	.	.	.
cord-104223-ht3ry9i0	211	1	These	these	DT
cord-104223-ht3ry9i0	211	2	regions	region	NNS
cord-104223-ht3ry9i0	211	3	of	of	IN
cord-104223-ht3ry9i0	211	4	the	the	DT
cord-104223-ht3ry9i0	211	5	TGN	TGN	NNP
cord-104223-ht3ry9i0	211	6	may	may	MD
cord-104223-ht3ry9i0	211	7	be	be	VB
cord-104223-ht3ry9i0	211	8	connected	connect	VBN
cord-104223-ht3ry9i0	211	9	by	by	IN
cord-104223-ht3ry9i0	211	10	tubules	tubule	NNS
cord-104223-ht3ry9i0	211	11	,	,	,
cord-104223-ht3ry9i0	211	12	or	or	CC
cord-104223-ht3ry9i0	211	13	transport	transport	NN
cord-104223-ht3ry9i0	211	14	between	between	IN
cord-104223-ht3ry9i0	211	15	them	-PRON-	PRP
cord-104223-ht3ry9i0	211	16	may	may	MD
cord-104223-ht3ry9i0	211	17	occur	occur	VB
cord-104223-ht3ry9i0	211	18	through	through	IN
cord-104223-ht3ry9i0	211	19	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	211	20	.	.	.
cord-104223-ht3ry9i0	212	1	How	how	WRB
cord-104223-ht3ry9i0	212	2	are	be	VBP
cord-104223-ht3ry9i0	212	3	these	these	DT
cord-104223-ht3ry9i0	212	4	intermediates	intermediate	NNS
cord-104223-ht3ry9i0	212	5	segregated	segregate	VBN
cord-104223-ht3ry9i0	212	6	before	before	IN
cord-104223-ht3ry9i0	212	7	formation	formation	NN
cord-104223-ht3ry9i0	212	8	of	of	IN
cord-104223-ht3ry9i0	212	9	a	a	DT
cord-104223-ht3ry9i0	212	10	dense	dense	JJ
cord-104223-ht3ry9i0	212	11	core	core	NN
cord-104223-ht3ry9i0	212	12	?	?	.
cord-104223-ht3ry9i0	213	1	After	after	IN
cord-104223-ht3ry9i0	213	2	a	a	DT
cord-104223-ht3ry9i0	213	3	30-min	30-min	CD
cord-104223-ht3ry9i0	213	4	chase	chase	NN
cord-104223-ht3ry9i0	213	5	both	both	CC
cord-104223-ht3ry9i0	213	6	amino	amino	NNS
cord-104223-ht3ry9i0	213	7	and	and	CC
cord-104223-ht3ry9i0	213	8	carboxy	carboxy	NN
cord-104223-ht3ry9i0	214	1	terminal	terminal	JJ
cord-104223-ht3ry9i0	214	2	-	-	HYPH
cord-104223-ht3ry9i0	214	3	associated	associate	VBN
cord-104223-ht3ry9i0	214	4	grains	grain	NNS
cord-104223-ht3ry9i0	214	5	are	be	VBP
cord-104223-ht3ry9i0	214	6	found	find	VBN
cord-104223-ht3ry9i0	214	7	over	over	IN
cord-104223-ht3ry9i0	214	8	small	small	JJ
cord-104223-ht3ry9i0	214	9	imma-	imma-	JJ
cord-104223-ht3ry9i0	214	10	schematic	schematic	NN
cord-104223-ht3ry9i0	214	11	diagram	diagram	NN
cord-104223-ht3ry9i0	214	12	for	for	IN
cord-104223-ht3ry9i0	214	13	prohormone	prohormone	NN
cord-104223-ht3ry9i0	214	14	processing	processing	NN
cord-104223-ht3ry9i0	214	15	and	and	CC
cord-104223-ht3ry9i0	214	16	sorting	sorting	NN
cord-104223-ht3ry9i0	214	17	in	in	IN
cord-104223-ht3ry9i0	214	18	the	the	DT
cord-104223-ht3ry9i0	214	19	bag	bag	NN
cord-104223-ht3ry9i0	214	20	ceils	ceils	NNP
cord-104223-ht3ry9i0	214	21	is	be	VBZ
cord-104223-ht3ry9i0	214	22	described	describe	VBN
cord-104223-ht3ry9i0	214	23	fully	fully	RB
cord-104223-ht3ry9i0	214	24	in	in	IN
cord-104223-ht3ry9i0	214	25	Discussion	Discussion	NNP
cord-104223-ht3ry9i0	214	26	.	.	.
cord-104223-ht3ry9i0	215	1	A	a	DT
cord-104223-ht3ry9i0	215	2	solid	solid	JJ
cord-104223-ht3ry9i0	215	3	line	line	NN
cord-104223-ht3ry9i0	215	4	represents	represent	VBZ
cord-104223-ht3ry9i0	215	5	the	the	DT
cord-104223-ht3ry9i0	215	6	carboxyterminal	carboxyterminal	JJ
cord-104223-ht3ry9i0	215	7	intermediate	intermediate	NN
cord-104223-ht3ry9i0	215	8	;	;	:
cord-104223-ht3ry9i0	215	9	a	a	DT
cord-104223-ht3ry9i0	215	10	dotted	dotted	JJ
cord-104223-ht3ry9i0	215	11	line	line	NN
cord-104223-ht3ry9i0	215	12	represents	represent	VBZ
cord-104223-ht3ry9i0	215	13	the	the	DT
cord-104223-ht3ry9i0	215	14	amino	amino	NN
cord-104223-ht3ry9i0	215	15	-	-	HYPH
cord-104223-ht3ry9i0	215	16	terminal	terminal	NN
cord-104223-ht3ry9i0	215	17	intermediate	intermediate	NN
cord-104223-ht3ry9i0	215	18	;	;	:
cord-104223-ht3ry9i0	215	19	a	a	DT
cord-104223-ht3ry9i0	215	20	dotted	dotted	JJ
cord-104223-ht3ry9i0	215	21	line	line	NN
cord-104223-ht3ry9i0	215	22	attached	attach	VBN
cord-104223-ht3ry9i0	215	23	to	to	IN
cord-104223-ht3ry9i0	215	24	a	a	DT
cord-104223-ht3ry9i0	215	25	solid	solid	JJ
cord-104223-ht3ry9i0	215	26	line	line	NN
cord-104223-ht3ry9i0	215	27	represents	represent	VBZ
cord-104223-ht3ry9i0	215	28	the	the	DT
cord-104223-ht3ry9i0	215	29	ELH	ELH	NNP
cord-104223-ht3ry9i0	215	30	prohormone	prohormone	NN
cord-104223-ht3ry9i0	215	31	;	;	:
cord-104223-ht3ry9i0	215	32	smaller	small	JJR
cord-104223-ht3ry9i0	215	33	lines	line	NNS
cord-104223-ht3ry9i0	215	34	represent	represent	VBP
cord-104223-ht3ry9i0	215	35	the	the	DT
cord-104223-ht3ry9i0	215	36	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	215	37	-	-	HYPH
cord-104223-ht3ry9i0	215	38	terminal	terminal	NN
cord-104223-ht3ry9i0	215	39	final	final	JJ
cord-104223-ht3ry9i0	215	40	product	product	NN
cord-104223-ht3ry9i0	215	41	peptides	peptide	NNS
cord-104223-ht3ry9i0	215	42	;	;	:
cord-104223-ht3ry9i0	215	43	and	and	CC
cord-104223-ht3ry9i0	215	44	dots	dot	NNS
cord-104223-ht3ry9i0	215	45	represent	represent	VBP
cord-104223-ht3ry9i0	215	46	the	the	DT
cord-104223-ht3ry9i0	215	47	amino	amino	NN
cord-104223-ht3ry9i0	215	48	-	-	HYPH
cord-104223-ht3ry9i0	215	49	terminal	terminal	NN
cord-104223-ht3ry9i0	215	50	final	final	JJ
cord-104223-ht3ry9i0	215	51	product	product	NN
cord-104223-ht3ry9i0	215	52	peptides	peptide	NNS
cord-104223-ht3ry9i0	215	53	.	.	.
cord-104223-ht3ry9i0	216	1	L	L	NNP
cord-104223-ht3ry9i0	216	2	indicates	indicate	VBZ
cord-104223-ht3ry9i0	216	3	an	an	DT
cord-104223-ht3ry9i0	216	4	organelle	organelle	NN
cord-104223-ht3ry9i0	216	5	of	of	IN
cord-104223-ht3ry9i0	216	6	degradative	degradative	JJ
cord-104223-ht3ry9i0	216	7	function	function	NN
cord-104223-ht3ry9i0	216	8	(	(	-LRB-
cord-104223-ht3ry9i0	216	9	endosome	endosome	NN
cord-104223-ht3ry9i0	216	10	or	or	CC
cord-104223-ht3ry9i0	216	11	lysosome	lysosome	NN
cord-104223-ht3ry9i0	216	12	)	)	-RRB-
cord-104223-ht3ry9i0	216	13	.	.	.
cord-104223-ht3ry9i0	217	1	Direct	direct	JJ
cord-104223-ht3ry9i0	217	2	connection	connection	NN
cord-104223-ht3ry9i0	217	3	between	between	IN
cord-104223-ht3ry9i0	217	4	the	the	DT
cord-104223-ht3ry9i0	217	5	part	part	NN
cord-104223-ht3ry9i0	217	6	of	of	IN
cord-104223-ht3ry9i0	217	7	the	the	DT
cord-104223-ht3ry9i0	217	8	TGN	TGN	NNP
cord-104223-ht3ry9i0	217	9	containing	contain	VBG
cord-104223-ht3ry9i0	217	10	large	large	JJ
cord-104223-ht3ry9i0	217	11	immature	immature	JJ
cord-104223-ht3ry9i0	217	12	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	217	13	and	and	CC
cord-104223-ht3ry9i0	217	14	small	small	JJ
cord-104223-ht3ry9i0	217	15	immature	immature	JJ
cord-104223-ht3ry9i0	217	16	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	217	17	is	be	VBZ
cord-104223-ht3ry9i0	217	18	putative	putative	JJ
cord-104223-ht3ry9i0	217	19	and	and	CC
cord-104223-ht3ry9i0	217	20	this	this	DT
cord-104223-ht3ry9i0	217	21	is	be	VBZ
cord-104223-ht3ry9i0	217	22	represented	represent	VBN
cord-104223-ht3ry9i0	217	23	by	by	IN
cord-104223-ht3ry9i0	217	24	a	a	DT
cord-104223-ht3ry9i0	217	25	dotted	dotted	JJ
cord-104223-ht3ry9i0	217	26	line	line	NN
cord-104223-ht3ry9i0	217	27	.	.	.
cord-104223-ht3ry9i0	218	1	Shading	shading	NN
cord-104223-ht3ry9i0	218	2	represents	represent	VBZ
cord-104223-ht3ry9i0	218	3	acid	acid	NN
cord-104223-ht3ry9i0	218	4	phosphatase	phosphatase	NN
cord-104223-ht3ry9i0	218	5	-	-	HYPH
cord-104223-ht3ry9i0	218	6	positive	positive	JJ
cord-104223-ht3ry9i0	218	7	membranes	membrane	NNS
cord-104223-ht3ry9i0	218	8	.	.	.
cord-104223-ht3ry9i0	219	1	The	the	DT
cord-104223-ht3ry9i0	219	2	small	small	JJ
cord-104223-ht3ry9i0	219	3	amino	amino	NNS
cord-104223-ht3ry9i0	219	4	-	-	,
cord-104223-ht3ry9i0	219	5	and	and	CC
cord-104223-ht3ry9i0	219	6	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	219	7	-	-	HYPH
cord-104223-ht3ry9i0	219	8	terminal	terminal	NN
cord-104223-ht3ry9i0	219	9	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	219	10	will	will	MD
cord-104223-ht3ry9i0	219	11	be	be	VB
cord-104223-ht3ry9i0	219	12	transported	transport	VBN
cord-104223-ht3ry9i0	219	13	to	to	IN
cord-104223-ht3ry9i0	219	14	processes	process	NNS
cord-104223-ht3ry9i0	219	15	for	for	IN
cord-104223-ht3ry9i0	219	16	regulated	regulated	JJ
cord-104223-ht3ry9i0	219	17	release	release	NN
cord-104223-ht3ry9i0	219	18	,	,	,
cord-104223-ht3ry9i0	219	19	where	where	WRB
cord-104223-ht3ry9i0	219	20	they	-PRON-	PRP
cord-104223-ht3ry9i0	219	21	are	be	VBP
cord-104223-ht3ry9i0	219	22	present	present	JJ
cord-104223-ht3ry9i0	219	23	at	at	IN
cord-104223-ht3ry9i0	219	24	a	a	DT
cord-104223-ht3ry9i0	219	25	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	219	26	-	-	HYPH
cord-104223-ht3ry9i0	219	27	toamino	toamino	NN
cord-104223-ht3ry9i0	219	28	terminal	terminal	JJ
cord-104223-ht3ry9i0	219	29	ratio	ratio	NN
cord-104223-ht3ry9i0	219	30	of	of	IN
cord-104223-ht3ry9i0	219	31	5:1	5:1	CD
cord-104223-ht3ry9i0	219	32	.	.	.
cord-104223-ht3ry9i0	220	1	ture	ture	NN
cord-104223-ht3ry9i0	220	2	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	220	3	and	and	CC
cord-104223-ht3ry9i0	220	4	clear	clear	JJ
cord-104223-ht3ry9i0	220	5	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	220	6	.	.	.
cord-104223-ht3ry9i0	221	1	Although	although	IN
cord-104223-ht3ry9i0	221	2	the	the	DT
cord-104223-ht3ry9i0	221	3	compartment	compartment	NN
cord-104223-ht3ry9i0	221	4	of	of	IN
cord-104223-ht3ry9i0	221	5	clear	clear	JJ
cord-104223-ht3ry9i0	221	6	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	221	7	is	be	VBZ
cord-104223-ht3ry9i0	221	8	obviously	obviously	RB
cord-104223-ht3ry9i0	221	9	heterogeneous	heterogeneous	JJ
cord-104223-ht3ry9i0	221	10	,	,	,
cord-104223-ht3ry9i0	221	11	the	the	DT
cord-104223-ht3ry9i0	221	12	location	location	NN
cord-104223-ht3ry9i0	221	13	and	and	CC
cord-104223-ht3ry9i0	221	14	the	the	DT
cord-104223-ht3ry9i0	221	15	time	time	NN
cord-104223-ht3ry9i0	221	16	course	course	NN
cord-104223-ht3ry9i0	221	17	of	of	IN
cord-104223-ht3ry9i0	221	18	counts	count	NNS
cord-104223-ht3ry9i0	221	19	moving	move	VBG
cord-104223-ht3ry9i0	221	20	into	into	IN
cord-104223-ht3ry9i0	221	21	these	these	DT
cord-104223-ht3ry9i0	221	22	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	221	23	is	be	VBZ
cord-104223-ht3ry9i0	221	24	most	most	RBS
cord-104223-ht3ry9i0	221	25	consistent	consistent	JJ
cord-104223-ht3ry9i0	221	26	with	with	IN
cord-104223-ht3ry9i0	221	27	their	-PRON-	PRP$
cord-104223-ht3ry9i0	221	28	arising	arise	VBG
cord-104223-ht3ry9i0	221	29	from	from	IN
cord-104223-ht3ry9i0	221	30	sections	section	NNS
cord-104223-ht3ry9i0	221	31	through	through	IN
cord-104223-ht3ry9i0	221	32	the	the	DT
cord-104223-ht3ry9i0	221	33	TGN	TGN	NNP
cord-104223-ht3ry9i0	221	34	.	.	.
cord-104223-ht3ry9i0	222	1	The	the	DT
cord-104223-ht3ry9i0	222	2	lack	lack	NN
cord-104223-ht3ry9i0	222	3	of	of	IN
cord-104223-ht3ry9i0	222	4	grains	grain	NNS
cord-104223-ht3ry9i0	222	5	located	locate	VBN
cord-104223-ht3ry9i0	222	6	over	over	IN
cord-104223-ht3ry9i0	222	7	clear	clear	JJ
cord-104223-ht3ry9i0	222	8	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	222	9	in	in	IN
cord-104223-ht3ry9i0	222	10	other	other	JJ
cord-104223-ht3ry9i0	222	11	EM	EM	NNP
cord-104223-ht3ry9i0	222	12	autoradiographic	autoradiographic	NNP
cord-104223-ht3ry9i0	222	13	studies	study	NNS
cord-104223-ht3ry9i0	222	14	of	of	IN
cord-104223-ht3ry9i0	222	15	neuropeptide	neuropeptide	NN
cord-104223-ht3ry9i0	222	16	transport	transport	NN
cord-104223-ht3ry9i0	222	17	(	(	-LRB-
cord-104223-ht3ry9i0	222	18	Saltpeter	Saltpeter	NNP
cord-104223-ht3ry9i0	222	19	and	and	CC
cord-104223-ht3ry9i0	222	20	Farquhar	Farquhar	NNP
cord-104223-ht3ry9i0	222	21	,	,	,
cord-104223-ht3ry9i0	222	22	1981	1981	CD
cord-104223-ht3ry9i0	222	23	)	)	-RRB-
cord-104223-ht3ry9i0	222	24	may	may	MD
cord-104223-ht3ry9i0	222	25	be	be	VB
cord-104223-ht3ry9i0	222	26	due	due	JJ
cord-104223-ht3ry9i0	222	27	to	to	IN
cord-104223-ht3ry9i0	222	28	an	an	DT
cord-104223-ht3ry9i0	222	29	earlier	early	JJR
cord-104223-ht3ry9i0	222	30	peptide	peptide	NN
cord-104223-ht3ry9i0	222	31	condensation	condensation	NN
cord-104223-ht3ry9i0	222	32	event	event	NN
cord-104223-ht3ry9i0	222	33	in	in	IN
cord-104223-ht3ry9i0	222	34	that	that	DT
cord-104223-ht3ry9i0	222	35	system	system	NN
cord-104223-ht3ry9i0	222	36	.	.	.
cord-104223-ht3ry9i0	223	1	Amino	amino	NN
cord-104223-ht3ry9i0	223	2	terminal	terminal	NN
cord-104223-ht3ry9i0	223	3	-	-	HYPH
cord-104223-ht3ry9i0	223	4	associated	associate	VBN
cord-104223-ht3ry9i0	223	5	radioactivity	radioactivity	NN
cord-104223-ht3ry9i0	223	6	then	then	RB
cord-104223-ht3ry9i0	223	7	decreases	decrease	VBZ
cord-104223-ht3ry9i0	223	8	in	in	IN
cord-104223-ht3ry9i0	223	9	clear	clear	JJ
cord-104223-ht3ry9i0	223	10	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	223	11	and	and	CC
cord-104223-ht3ry9i0	223	12	small	small	JJ
cord-104223-ht3ry9i0	223	13	immature	immature	JJ
cord-104223-ht3ry9i0	223	14	granules	granule	NNS
cord-104223-ht3ry9i0	223	15	and	and	CC
cord-104223-ht3ry9i0	223	16	increases	increase	NNS
cord-104223-ht3ry9i0	223	17	in	in	IN
cord-104223-ht3ry9i0	223	18	large	large	JJ
cord-104223-ht3ry9i0	223	19	immature	immature	JJ
cord-104223-ht3ry9i0	223	20	granules	granule	NNS
cord-104223-ht3ry9i0	223	21	.	.	.
cord-104223-ht3ry9i0	224	1	It	-PRON-	PRP
cord-104223-ht3ry9i0	224	2	is	be	VBZ
cord-104223-ht3ry9i0	224	3	the	the	DT
cord-104223-ht3ry9i0	224	4	selective	selective	JJ
cord-104223-ht3ry9i0	224	5	movement	movement	NN
cord-104223-ht3ry9i0	224	6	of	of	IN
cord-104223-ht3ry9i0	224	7	the	the	DT
cord-104223-ht3ry9i0	224	8	amino	amino	NN
cord-104223-ht3ry9i0	224	9	-	-	HYPH
cord-104223-ht3ry9i0	224	10	terminal	terminal	NN
cord-104223-ht3ry9i0	224	11	intermediate	intermediate	NN
cord-104223-ht3ry9i0	224	12	to	to	TO
cord-104223-ht3ry9i0	224	13	large	large	JJ
cord-104223-ht3ry9i0	224	14	immature	immature	JJ
cord-104223-ht3ry9i0	224	15	granules	granule	NNS
cord-104223-ht3ry9i0	224	16	and/or	and/or	CC
cord-104223-ht3ry9i0	224	17	the	the	DT
cord-104223-ht3ry9i0	224	18	selective	selective	JJ
cord-104223-ht3ry9i0	224	19	retention	retention	NN
cord-104223-ht3ry9i0	224	20	of	of	IN
cord-104223-ht3ry9i0	224	21	the	the	DT
cord-104223-ht3ry9i0	224	22	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	224	23	-	-	HYPH
cord-104223-ht3ry9i0	224	24	terminal	terminal	NN
cord-104223-ht3ry9i0	224	25	intermediate	intermediate	NN
cord-104223-ht3ry9i0	224	26	in	in	IN
cord-104223-ht3ry9i0	224	27	small	small	JJ
cord-104223-ht3ry9i0	224	28	immature	immature	JJ
cord-104223-ht3ry9i0	224	29	granules	granule	NNS
cord-104223-ht3ry9i0	224	30	that	that	WDT
cord-104223-ht3ry9i0	224	31	underlies	underlie	VBZ
cord-104223-ht3ry9i0	224	32	sorting	sort	VBG
cord-104223-ht3ry9i0	224	33	within	within	IN
cord-104223-ht3ry9i0	224	34	the	the	DT
cord-104223-ht3ry9i0	224	35	regulated	regulated	JJ
cord-104223-ht3ry9i0	224	36	pathway	pathway	NN
cord-104223-ht3ry9i0	224	37	.	.	.
cord-104223-ht3ry9i0	225	1	These	these	DT
cord-104223-ht3ry9i0	225	2	results	result	NNS
cord-104223-ht3ry9i0	225	3	suggest	suggest	VBP
cord-104223-ht3ry9i0	225	4	a	a	DT
cord-104223-ht3ry9i0	225	5	flow	flow	NN
cord-104223-ht3ry9i0	225	6	of	of	IN
cord-104223-ht3ry9i0	225	7	the	the	DT
cord-104223-ht3ry9i0	225	8	amino	amino	NN
cord-104223-ht3ry9i0	225	9	-	-	HYPH
cord-104223-ht3ry9i0	225	10	terminal	terminal	NN
cord-104223-ht3ry9i0	225	11	intermediate	intermediate	NN
cord-104223-ht3ry9i0	225	12	through	through	IN
cord-104223-ht3ry9i0	225	13	the	the	DT
cord-104223-ht3ry9i0	225	14	TGN	TGN	NNP
cord-104223-ht3ry9i0	225	15	from	from	IN
cord-104223-ht3ry9i0	225	16	an	an	DT
cord-104223-ht3ry9i0	225	17	early	early	JJ
cord-104223-ht3ry9i0	225	18	region	region	NN
cord-104223-ht3ry9i0	225	19	that	that	WDT
cord-104223-ht3ry9i0	225	20	conrains	conrain	VBZ
cord-104223-ht3ry9i0	225	21	small	small	JJ
cord-104223-ht3ry9i0	225	22	immature	immature	JJ
cord-104223-ht3ry9i0	225	23	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	225	24	to	to	IN
cord-104223-ht3ry9i0	225	25	a	a	DT
cord-104223-ht3ry9i0	225	26	later	later	JJ
cord-104223-ht3ry9i0	225	27	region	region	NN
cord-104223-ht3ry9i0	225	28	that	that	WDT
cord-104223-ht3ry9i0	225	29	contains	contain	VBZ
cord-104223-ht3ry9i0	225	30	large	large	JJ
cord-104223-ht3ry9i0	225	31	immature	immature	JJ
cord-104223-ht3ry9i0	225	32	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	225	33	.	.	.
cord-104223-ht3ry9i0	226	1	Later	later	JJ
cord-104223-ht3ry9i0	226	2	cleavages	cleavage	NNS
cord-104223-ht3ry9i0	226	3	occur	occur	VBP
cord-104223-ht3ry9i0	226	4	in	in	IN
cord-104223-ht3ry9i0	226	5	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	226	6	after	after	IN
cord-104223-ht3ry9i0	226	7	leaving	leave	VBG
cord-104223-ht3ry9i0	226	8	the	the	DT
cord-104223-ht3ry9i0	226	9	TGN	TGN	NNP
cord-104223-ht3ry9i0	226	10	,	,	,
cord-104223-ht3ry9i0	226	11	presumably	presumably	RB
cord-104223-ht3ry9i0	226	12	due	due	IN
cord-104223-ht3ry9i0	226	13	to	to	IN
cord-104223-ht3ry9i0	226	14	activation	activation	NN
cord-104223-ht3ry9i0	226	15	of	of	IN
cord-104223-ht3ry9i0	226	16	enzymes	enzyme	NNS
cord-104223-ht3ry9i0	226	17	by	by	IN
cord-104223-ht3ry9i0	226	18	the	the	DT
cord-104223-ht3ry9i0	226	19	acidification	acidification	NN
cord-104223-ht3ry9i0	226	20	of	of	IN
cord-104223-ht3ry9i0	226	21	this	this	DT
cord-104223-ht3ry9i0	226	22	granule	granule	NN
cord-104223-ht3ry9i0	226	23	(	(	-LRB-
cord-104223-ht3ry9i0	226	24	Orci	Orci	NNP
cord-104223-ht3ry9i0	226	25	et	et	NNP
cord-104223-ht3ry9i0	226	26	al	al	NNP
cord-104223-ht3ry9i0	226	27	.	.	NNP
cord-104223-ht3ry9i0	226	28	,	,	,
cord-104223-ht3ry9i0	226	29	1987	1987	CD
cord-104223-ht3ry9i0	226	30	;	;	:
cord-104223-ht3ry9i0	226	31	Anderson	Anderson	NNP
cord-104223-ht3ry9i0	226	32	and	and	CC
cord-104223-ht3ry9i0	226	33	Orci	Orci	NNP
cord-104223-ht3ry9i0	226	34	,	,	,
cord-104223-ht3ry9i0	226	35	1988	1988	CD
cord-104223-ht3ry9i0	226	36	)	)	-RRB-
cord-104223-ht3ry9i0	226	37	;	;	:
cord-104223-ht3ry9i0	226	38	these	these	DT
cord-104223-ht3ry9i0	226	39	cleavages	cleavage	NNS
cord-104223-ht3ry9i0	226	40	are	be	VBP
cord-104223-ht3ry9i0	226	41	blocked	block	VBN
cord-104223-ht3ry9i0	226	42	by	by	IN
cord-104223-ht3ry9i0	226	43	monensin	monensin	NNP
cord-104223-ht3ry9i0	226	44	.	.	.
cord-104223-ht3ry9i0	227	1	We	-PRON-	PRP
cord-104223-ht3ry9i0	227	2	propose	propose	VBP
cord-104223-ht3ry9i0	227	3	that	that	IN
cord-104223-ht3ry9i0	227	4	the	the	DT
cord-104223-ht3ry9i0	227	5	small	small	JJ
cord-104223-ht3ry9i0	227	6	amino	amino	NNS
cord-104223-ht3ry9i0	227	7	terminal	terminal	NN
cord-104223-ht3ry9i0	227	8	-	-	HYPH
cord-104223-ht3ry9i0	227	9	containing	contain	VBG
cord-104223-ht3ry9i0	227	10	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	227	11	that	that	WDT
cord-104223-ht3ry9i0	227	12	are	be	VBP
cord-104223-ht3ry9i0	227	13	transported	transport	VBN
cord-104223-ht3ry9i0	227	14	to	to	IN
cord-104223-ht3ry9i0	227	15	processes	process	NNS
cord-104223-ht3ry9i0	227	16	arise	arise	VBP
cord-104223-ht3ry9i0	227	17	from	from	IN
cord-104223-ht3ry9i0	227	18	the	the	DT
cord-104223-ht3ry9i0	227	19	larger	large	JJR
cord-104223-ht3ry9i0	227	20	immature	immature	JJ
cord-104223-ht3ry9i0	227	21	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	227	22	,	,	,
cord-104223-ht3ry9i0	227	23	although	although	IN
cord-104223-ht3ry9i0	227	24	the	the	DT
cord-104223-ht3ry9i0	227	25	evidence	evidence	NN
cord-104223-ht3ry9i0	227	26	supporting	support	VBG
cord-104223-ht3ry9i0	227	27	this	this	DT
cord-104223-ht3ry9i0	227	28	idea	idea	NN
cord-104223-ht3ry9i0	227	29	is	be	VBZ
cord-104223-ht3ry9i0	227	30	not	not	RB
cord-104223-ht3ry9i0	227	31	yet	yet	RB
cord-104223-ht3ry9i0	227	32	conclusive	conclusive	JJ
cord-104223-ht3ry9i0	227	33	.	.	.
cord-104223-ht3ry9i0	228	1	In	in	IN
cord-104223-ht3ry9i0	228	2	support	support	NN
cord-104223-ht3ry9i0	228	3	of	of	IN
cord-104223-ht3ry9i0	228	4	this	this	DT
cord-104223-ht3ry9i0	228	5	idea	idea	NN
cord-104223-ht3ry9i0	228	6	,	,	,
cord-104223-ht3ry9i0	228	7	a	a	DT
cord-104223-ht3ry9i0	228	8	higher	high	JJR
cord-104223-ht3ry9i0	228	9	proportion	proportion	NN
cord-104223-ht3ry9i0	228	10	of	of	IN
cord-104223-ht3ry9i0	228	11	processing	process	VBG
cord-104223-ht3ry9i0	228	12	intermediate	intermediate	JJ
cord-104223-ht3ry9i0	228	13	immunoreactivity	immunoreactivity	NN
cord-104223-ht3ry9i0	228	14	is	be	VBZ
cord-104223-ht3ry9i0	228	15	found	find	VBN
cord-104223-ht3ry9i0	228	16	in	in	IN
cord-104223-ht3ry9i0	228	17	the	the	DT
cord-104223-ht3ry9i0	228	18	large	large	JJ
cord-104223-ht3ry9i0	228	19	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	228	20	(	(	-LRB-
cord-104223-ht3ry9i0	228	21	Kreiner	Kreiner	NNP
cord-104223-ht3ry9i0	228	22	et	et	NNP
cord-104223-ht3ry9i0	228	23	al	al	NNP
cord-104223-ht3ry9i0	228	24	.	.	NNP
cord-104223-ht3ry9i0	228	25	,	,	,
cord-104223-ht3ry9i0	228	26	1989	1989	CD
cord-104223-ht3ry9i0	228	27	)	)	-RRB-
cord-104223-ht3ry9i0	228	28	.	.	.
cord-104223-ht3ry9i0	229	1	Furthermore	furthermore	RB
cord-104223-ht3ry9i0	229	2	,	,	,
cord-104223-ht3ry9i0	229	3	in	in	IN
cord-104223-ht3ry9i0	229	4	[	[	-LRB-
cord-104223-ht3ry9i0	229	5	3H]Phelabeled	3h]phelabeled	JJ
cord-104223-ht3ry9i0	229	6	experiments	experiment	NNS
cord-104223-ht3ry9i0	229	7	,	,	,
cord-104223-ht3ry9i0	229	8	a	a	DT
cord-104223-ht3ry9i0	229	9	high	high	JJ
cord-104223-ht3ry9i0	229	10	concentration	concentration	NN
cord-104223-ht3ry9i0	229	11	of	of	IN
cord-104223-ht3ry9i0	229	12	autoradiographic	autoradiographic	JJ
cord-104223-ht3ry9i0	229	13	grains	grain	NNS
cord-104223-ht3ry9i0	229	14	is	be	VBZ
cord-104223-ht3ry9i0	229	15	seen	see	VBN
cord-104223-ht3ry9i0	229	16	in	in	IN
cord-104223-ht3ry9i0	229	17	mature	mature	JJ
cord-104223-ht3ry9i0	229	18	small	small	JJ
cord-104223-ht3ry9i0	229	19	DCVs	dcv	NNS
cord-104223-ht3ry9i0	229	20	only	only	RB
cord-104223-ht3ry9i0	229	21	after	after	IN
cord-104223-ht3ry9i0	229	22	a	a	DT
cord-104223-ht3ry9i0	229	23	12-h	12-h	CD
cord-104223-ht3ry9i0	229	24	chase	chase	NN
cord-104223-ht3ry9i0	229	25	but	but	CC
cord-104223-ht3ry9i0	229	26	not	not	RB
cord-104223-ht3ry9i0	229	27	at	at	IN
cord-104223-ht3ry9i0	229	28	earlier	early	JJR
cord-104223-ht3ry9i0	229	29	time	time	NN
cord-104223-ht3ry9i0	229	30	points	point	NNS
cord-104223-ht3ry9i0	229	31	(	(	-LRB-
cord-104223-ht3ry9i0	229	32	Table	table	NN
cord-104223-ht3ry9i0	229	33	I	i	CD
cord-104223-ht3ry9i0	229	34	)	)	-RRB-
cord-104223-ht3ry9i0	229	35	.	.	.
cord-104223-ht3ry9i0	230	1	The	the	DT
cord-104223-ht3ry9i0	230	2	large	large	JJ
cord-104223-ht3ry9i0	230	3	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	230	4	appear	appear	VBP
cord-104223-ht3ry9i0	230	5	to	to	TO
cord-104223-ht3ry9i0	230	6	have	have	VB
cord-104223-ht3ry9i0	230	7	a	a	DT
cord-104223-ht3ry9i0	230	8	short	short	JJ
cord-104223-ht3ry9i0	230	9	half	half	JJ
cord-104223-ht3ry9i0	230	10	-	-	HYPH
cord-104223-ht3ry9i0	230	11	life	life	NN
cord-104223-ht3ry9i0	230	12	since	since	IN
cord-104223-ht3ry9i0	230	13	>	>	XX
cord-104223-ht3ry9i0	230	14	50	50	CD
cord-104223-ht3ry9i0	230	15	%	%	NN
cord-104223-ht3ry9i0	230	16	of	of	IN
cord-104223-ht3ry9i0	230	17	the	the	DT
cord-104223-ht3ry9i0	230	18	counts	count	NNS
cord-104223-ht3ry9i0	230	19	associated	associate	VBN
cord-104223-ht3ry9i0	230	20	with	with	IN
cord-104223-ht3ry9i0	230	21	these	these	DT
cord-104223-ht3ry9i0	230	22	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	230	23	appear	appear	VBP
cord-104223-ht3ry9i0	230	24	in	in	IN
cord-104223-ht3ry9i0	230	25	profiles	profile	NNS
cord-104223-ht3ry9i0	230	26	that	that	WDT
cord-104223-ht3ry9i0	230	27	appear	appear	VBP
cord-104223-ht3ry9i0	230	28	to	to	TO
cord-104223-ht3ry9i0	230	29	be	be	VB
cord-104223-ht3ry9i0	230	30	fated	fate	VBN
cord-104223-ht3ry9i0	230	31	for	for	IN
cord-104223-ht3ry9i0	230	32	degradation	degradation	NN
cord-104223-ht3ry9i0	230	33	after	after	IN
cord-104223-ht3ry9i0	230	34	a	a	DT
cord-104223-ht3ry9i0	230	35	12-h	12-h	CD
cord-104223-ht3ry9i0	230	36	chase	chase	NN
cord-104223-ht3ry9i0	230	37	.	.	.
cord-104223-ht3ry9i0	231	1	The	the	DT
cord-104223-ht3ry9i0	231	2	molecular	molecular	JJ
cord-104223-ht3ry9i0	231	3	mechanism	mechanism	NN
cord-104223-ht3ry9i0	231	4	by	by	IN
cord-104223-ht3ry9i0	231	5	which	which	WDT
cord-104223-ht3ry9i0	231	6	the	the	DT
cord-104223-ht3ry9i0	231	7	two	two	CD
cord-104223-ht3ry9i0	231	8	processing	processing	NN
cord-104223-ht3ry9i0	231	9	intermediates	intermediate	NNS
cord-104223-ht3ry9i0	231	10	are	be	VBP
cord-104223-ht3ry9i0	231	11	segregated	segregate	VBN
cord-104223-ht3ry9i0	231	12	from	from	IN
cord-104223-ht3ry9i0	231	13	each	each	DT
cord-104223-ht3ry9i0	231	14	other	other	JJ
cord-104223-ht3ry9i0	231	15	is	be	VBZ
cord-104223-ht3ry9i0	231	16	still	still	RB
cord-104223-ht3ry9i0	231	17	an	an	DT
cord-104223-ht3ry9i0	231	18	open	open	JJ
cord-104223-ht3ry9i0	231	19	question	question	NN
cord-104223-ht3ry9i0	231	20	.	.	.
cord-104223-ht3ry9i0	232	1	One	one	CD
cord-104223-ht3ry9i0	232	2	appealing	appeal	VBG
cord-104223-ht3ry9i0	232	3	possibility	possibility	NN
cord-104223-ht3ry9i0	232	4	is	be	VBZ
cord-104223-ht3ry9i0	232	5	that	that	IN
cord-104223-ht3ry9i0	232	6	the	the	DT
cord-104223-ht3ry9i0	232	7	carboxyterminal	carboxyterminal	JJ
cord-104223-ht3ry9i0	232	8	intermediate	intermediate	NN
cord-104223-ht3ry9i0	232	9	selectively	selectively	RB
cord-104223-ht3ry9i0	232	10	condenses	condense	VBZ
cord-104223-ht3ry9i0	232	11	in	in	IN
cord-104223-ht3ry9i0	232	12	the	the	DT
cord-104223-ht3ry9i0	232	13	early	early	JJ
cord-104223-ht3ry9i0	232	14	region	region	NN
cord-104223-ht3ry9i0	232	15	of	of	IN
cord-104223-ht3ry9i0	232	16	the	the	DT
cord-104223-ht3ry9i0	232	17	TGN	TGN	NNP
cord-104223-ht3ry9i0	232	18	,	,	,
cord-104223-ht3ry9i0	232	19	leaving	leave	VBG
cord-104223-ht3ry9i0	232	20	the	the	DT
cord-104223-ht3ry9i0	232	21	amino	amino	NN
cord-104223-ht3ry9i0	232	22	-	-	HYPH
cord-104223-ht3ry9i0	232	23	terminal	terminal	NN
cord-104223-ht3ry9i0	232	24	intermediate	intermediate	NN
cord-104223-ht3ry9i0	232	25	soluble	soluble	JJ
cord-104223-ht3ry9i0	232	26	.	.	.
cord-104223-ht3ry9i0	233	1	Perhaps	perhaps	RB
cord-104223-ht3ry9i0	233	2	different	different	JJ
cord-104223-ht3ry9i0	233	3	ionic	ionic	JJ
cord-104223-ht3ry9i0	233	4	conditions	condition	NNS
cord-104223-ht3ry9i0	233	5	or	or	CC
cord-104223-ht3ry9i0	233	6	different	different	JJ
cord-104223-ht3ry9i0	233	7	accessory	accessory	NN
cord-104223-ht3ry9i0	233	8	proteins	protein	NNS
cord-104223-ht3ry9i0	233	9	(	(	-LRB-
cord-104223-ht3ry9i0	233	10	Chung	Chung	NNP
cord-104223-ht3ry9i0	233	11	et	et	NNP
cord-104223-ht3ry9i0	233	12	al	al	NNP
cord-104223-ht3ry9i0	233	13	.	.	NNP
cord-104223-ht3ry9i0	233	14	,	,	,
cord-104223-ht3ry9i0	233	15	1989	1989	CD
cord-104223-ht3ry9i0	233	16	)	)	-RRB-
cord-104223-ht3ry9i0	233	17	located	locate	VBN
cord-104223-ht3ry9i0	233	18	in	in	IN
cord-104223-ht3ry9i0	233	19	the	the	DT
cord-104223-ht3ry9i0	233	20	late	late	JJ
cord-104223-ht3ry9i0	233	21	region	region	NN
cord-104223-ht3ry9i0	233	22	of	of	IN
cord-104223-ht3ry9i0	233	23	the	the	DT
cord-104223-ht3ry9i0	233	24	TGN	TGN	NNP
cord-104223-ht3ry9i0	233	25	would	would	MD
cord-104223-ht3ry9i0	233	26	allow	allow	VB
cord-104223-ht3ry9i0	233	27	the	the	DT
cord-104223-ht3ry9i0	233	28	amino	amino	NN
cord-104223-ht3ry9i0	233	29	-	-	HYPH
cord-104223-ht3ry9i0	233	30	terminal	terminal	NN
cord-104223-ht3ry9i0	233	31	portion	portion	NN
cord-104223-ht3ry9i0	233	32	of	of	IN
cord-104223-ht3ry9i0	233	33	the	the	DT
cord-104223-ht3ry9i0	233	34	prohormone	prohormone	NN
cord-104223-ht3ry9i0	233	35	to	to	TO
cord-104223-ht3ry9i0	233	36	condense	condense	VB
cord-104223-ht3ry9i0	233	37	at	at	IN
cord-104223-ht3ry9i0	233	38	this	this	DT
cord-104223-ht3ry9i0	233	39	site	site	NN
cord-104223-ht3ry9i0	233	40	.	.	.
cord-104223-ht3ry9i0	234	1	A	a	DT
cord-104223-ht3ry9i0	234	2	differential	differential	JJ
cord-104223-ht3ry9i0	234	3	timing	timing	NN
cord-104223-ht3ry9i0	234	4	of	of	IN
cord-104223-ht3ry9i0	234	5	condensation	condensation	NN
cord-104223-ht3ry9i0	234	6	has	have	VBZ
cord-104223-ht3ry9i0	234	7	also	also	RB
cord-104223-ht3ry9i0	234	8	been	be	VBN
cord-104223-ht3ry9i0	234	9	proposed	propose	VBN
cord-104223-ht3ry9i0	234	10	to	to	TO
cord-104223-ht3ry9i0	234	11	explain	explain	VB
cord-104223-ht3ry9i0	234	12	the	the	DT
cord-104223-ht3ry9i0	234	13	separation	separation	NN
cord-104223-ht3ry9i0	234	14	of	of	IN
cord-104223-ht3ry9i0	234	15	prolactin	prolactin	NN
cord-104223-ht3ry9i0	234	16	and	and	CC
cord-104223-ht3ry9i0	234	17	growth	growth	NN
cord-104223-ht3ry9i0	234	18	hormone	hormone	NN
cord-104223-ht3ry9i0	234	19	in	in	IN
cord-104223-ht3ry9i0	234	20	somatomammotrophs	somatomammotrophs	NNP
cord-104223-ht3ry9i0	234	21	(	(	-LRB-
cord-104223-ht3ry9i0	234	22	Fumagilli	Fumagilli	NNP
cord-104223-ht3ry9i0	234	23	and	and	CC
cord-104223-ht3ry9i0	234	24	Zanini	Zanini	NNP
cord-104223-ht3ry9i0	234	25	,	,	,
cord-104223-ht3ry9i0	234	26	1985	1985	CD
cord-104223-ht3ry9i0	234	27	)	)	-RRB-
cord-104223-ht3ry9i0	234	28	.	.	.
cord-104223-ht3ry9i0	235	1	The	the	DT
cord-104223-ht3ry9i0	235	2	aggregated	aggregated	JJ
cord-104223-ht3ry9i0	235	3	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	235	4	-	-	HYPH
cord-104223-ht3ry9i0	235	5	terminal	terminal	NN
cord-104223-ht3ry9i0	235	6	portion	portion	NN
cord-104223-ht3ry9i0	235	7	of	of	IN
cord-104223-ht3ry9i0	235	8	the	the	DT
cord-104223-ht3ry9i0	235	9	precursor	precursor	NN
cord-104223-ht3ry9i0	235	10	may	may	MD
cord-104223-ht3ry9i0	235	11	be	be	VB
cord-104223-ht3ry9i0	235	12	prevented	prevent	VBN
cord-104223-ht3ry9i0	235	13	from	from	IN
cord-104223-ht3ry9i0	235	14	traveling	travel	VBG
cord-104223-ht3ry9i0	235	15	to	to	IN
cord-104223-ht3ry9i0	235	16	the	the	DT
cord-104223-ht3ry9i0	235	17	late	late	JJ
cord-104223-ht3ry9i0	235	18	compartment	compartment	NN
cord-104223-ht3ry9i0	235	19	either	either	CC
cord-104223-ht3ry9i0	235	20	through	through	IN
cord-104223-ht3ry9i0	235	21	steric	steric	JJ
cord-104223-ht3ry9i0	235	22	hindrance	hindrance	NN
cord-104223-ht3ry9i0	235	23	of	of	IN
cord-104223-ht3ry9i0	235	24	aggregates	aggregate	NNS
cord-104223-ht3ry9i0	235	25	moving	move	VBG
cord-104223-ht3ry9i0	235	26	through	through	IN
cord-104223-ht3ry9i0	235	27	small	small	JJ
cord-104223-ht3ry9i0	235	28	tubules	tubule	NNS
cord-104223-ht3ry9i0	235	29	,	,	,
cord-104223-ht3ry9i0	235	30	the	the	DT
cord-104223-ht3ry9i0	235	31	inability	inability	NN
cord-104223-ht3ry9i0	235	32	to	to	TO
cord-104223-ht3ry9i0	235	33	be	be	VB
cord-104223-ht3ry9i0	235	34	packaged	package	VBN
cord-104223-ht3ry9i0	235	35	into	into	IN
cord-104223-ht3ry9i0	235	36	small	small	JJ
cord-104223-ht3ry9i0	235	37	transport	transport	NN
cord-104223-ht3ry9i0	235	38	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	235	39	,	,	,
cord-104223-ht3ry9i0	235	40	or	or	CC
cord-104223-ht3ry9i0	235	41	a	a	DT
cord-104223-ht3ry9i0	235	42	specific	specific	JJ
cord-104223-ht3ry9i0	235	43	association	association	NN
cord-104223-ht3ry9i0	235	44	with	with	IN
cord-104223-ht3ry9i0	235	45	an	an	DT
cord-104223-ht3ry9i0	235	46	immobile	immobile	JJ
cord-104223-ht3ry9i0	235	47	membrane	membrane	NN
cord-104223-ht3ry9i0	235	48	-	-	HYPH
cord-104223-ht3ry9i0	235	49	bound	bind	VBN
cord-104223-ht3ry9i0	235	50	receptor	receptor	NN
cord-104223-ht3ry9i0	235	51	.	.	.
cord-104223-ht3ry9i0	236	1	Alternatively	alternatively	RB
cord-104223-ht3ry9i0	236	2	,	,	,
cord-104223-ht3ry9i0	236	3	movement	movement	NN
cord-104223-ht3ry9i0	236	4	of	of	IN
cord-104223-ht3ry9i0	236	5	the	the	DT
cord-104223-ht3ry9i0	236	6	amino	amino	NN
cord-104223-ht3ry9i0	236	7	-	-	HYPH
cord-104223-ht3ry9i0	236	8	terminal	terminal	NN
cord-104223-ht3ry9i0	236	9	portion	portion	NN
cord-104223-ht3ry9i0	236	10	of	of	IN
cord-104223-ht3ry9i0	236	11	the	the	DT
cord-104223-ht3ry9i0	236	12	precursor	precursor	NN
cord-104223-ht3ry9i0	236	13	may	may	MD
cord-104223-ht3ry9i0	236	14	be	be	VB
cord-104223-ht3ry9i0	236	15	mediated	mediate	VBN
cord-104223-ht3ry9i0	236	16	through	through	IN
cord-104223-ht3ry9i0	236	17	the	the	DT
cord-104223-ht3ry9i0	236	18	actions	action	NNS
cord-104223-ht3ry9i0	236	19	of	of	IN
cord-104223-ht3ry9i0	236	20	a	a	DT
cord-104223-ht3ry9i0	236	21	membrane	membrane	NN
cord-104223-ht3ry9i0	236	22	-	-	HYPH
cord-104223-ht3ry9i0	236	23	bound	bind	VBN
cord-104223-ht3ry9i0	236	24	recognition	recognition	NN
cord-104223-ht3ry9i0	236	25	system	system	NN
cord-104223-ht3ry9i0	236	26	.	.	.
cord-104223-ht3ry9i0	237	1	In	in	IN
cord-104223-ht3ry9i0	237	2	support	support	NN
cord-104223-ht3ry9i0	237	3	of	of	IN
cord-104223-ht3ry9i0	237	4	this	this	DT
cord-104223-ht3ry9i0	237	5	model	model	NN
cord-104223-ht3ry9i0	237	6	,	,	,
cord-104223-ht3ry9i0	237	7	the	the	DT
cord-104223-ht3ry9i0	237	8	bag	bag	NN
cord-104223-ht3ry9i0	237	9	cell	cell	NN
cord-104223-ht3ry9i0	237	10	amino	amino	NN
cord-104223-ht3ry9i0	237	11	-	-	HYPH
cord-104223-ht3ry9i0	237	12	terminal	terminal	NN
cord-104223-ht3ry9i0	237	13	intermediate	intermediate	NN
cord-104223-ht3ry9i0	237	14	(	(	-LRB-
cord-104223-ht3ry9i0	237	15	F2	f2	NN
cord-104223-ht3ry9i0	237	16	)	)	-RRB-
cord-104223-ht3ry9i0	237	17	is	be	VBZ
cord-104223-ht3ry9i0	237	18	associated	associate	VBN
cord-104223-ht3ry9i0	237	19	with	with	IN
cord-104223-ht3ry9i0	237	20	membranes	membrane	NNS
cord-104223-ht3ry9i0	237	21	at	at	IN
cord-104223-ht3ry9i0	237	22	a	a	DT
cord-104223-ht3ry9i0	237	23	time	time	NN
cord-104223-ht3ry9i0	237	24	point	point	NN
cord-104223-ht3ry9i0	237	25	(	(	-LRB-
cord-104223-ht3ry9i0	237	26	30-min	30-min	CD
cord-104223-ht3ry9i0	237	27	pulse	pulse	NN
cord-104223-ht3ry9i0	237	28	and	and	CC
cord-104223-ht3ry9i0	237	29	2-h	2-h	CD
cord-104223-ht3ry9i0	237	30	chase	chase	NN
cord-104223-ht3ry9i0	237	31	)	)	-RRB-
cord-104223-ht3ry9i0	237	32	when	when	WRB
cord-104223-ht3ry9i0	237	33	the	the	DT
cord-104223-ht3ry9i0	237	34	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	237	35	-	-	HYPH
cord-104223-ht3ry9i0	237	36	terminal	terminal	NN
cord-104223-ht3ry9i0	237	37	intermediate	intermediate	NN
cord-104223-ht3ry9i0	237	38	(	(	-LRB-
cord-104223-ht3ry9i0	237	39	I3	I3	NNP
cord-104223-ht3ry9i0	237	40	)	)	-RRB-
cord-104223-ht3ry9i0	237	41	is	be	VBZ
cord-104223-ht3ry9i0	237	42	not	not	RB
cord-104223-ht3ry9i0	237	43	membrane	membrane	NN
cord-104223-ht3ry9i0	237	44	associated	associate	VBN
cord-104223-ht3ry9i0	237	45	(	(	-LRB-
cord-104223-ht3ry9i0	237	46	Fisher	Fisher	NNP
cord-104223-ht3ry9i0	237	47	,	,	,
cord-104223-ht3ry9i0	237	48	J.	J.	NNP
cord-104223-ht3ry9i0	237	49	,	,	,
cord-104223-ht3ry9i0	237	50	manuscript	manuscript	NN
cord-104223-ht3ry9i0	237	51	in	in	IN
cord-104223-ht3ry9i0	237	52	preparation	preparation	NN
cord-104223-ht3ry9i0	237	53	;	;	,
cord-104223-ht3ry9i0	237	54	illustrated	illustrate	VBN
cord-104223-ht3ry9i0	237	55	in	in	IN
cord-104223-ht3ry9i0	237	56	Fig	Fig	NNP
cord-104223-ht3ry9i0	237	57	.	.	.
cord-104223-ht3ry9i0	237	58	8)	8)	NNP
cord-104223-ht3ry9i0	237	59	.	.	.
cord-104223-ht3ry9i0	238	1	A	a	DT
cord-104223-ht3ry9i0	238	2	selective	selective	JJ
cord-104223-ht3ry9i0	238	3	association	association	NN
cord-104223-ht3ry9i0	238	4	of	of	IN
cord-104223-ht3ry9i0	238	5	the	the	DT
cord-104223-ht3ry9i0	238	6	amino	amino	NN
cord-104223-ht3ry9i0	238	7	-	-	HYPH
cord-104223-ht3ry9i0	238	8	terminal	terminal	NN
cord-104223-ht3ry9i0	238	9	intermediate	intermediate	NN
cord-104223-ht3ry9i0	238	10	with	with	IN
cord-104223-ht3ry9i0	238	11	a	a	DT
cord-104223-ht3ry9i0	238	12	membrane	membrane	NN
cord-104223-ht3ry9i0	238	13	-	-	HYPH
cord-104223-ht3ry9i0	238	14	bound	bind	VBN
cord-104223-ht3ry9i0	238	15	receptor	receptor	NN
cord-104223-ht3ry9i0	238	16	would	would	MD
cord-104223-ht3ry9i0	238	17	allow	allow	VB
cord-104223-ht3ry9i0	238	18	a	a	DT
cord-104223-ht3ry9i0	238	19	vesicular	vesicular	JJ
cord-104223-ht3ry9i0	238	20	sorting	sorting	NN
cord-104223-ht3ry9i0	238	21	mechanism	mechanism	NN
cord-104223-ht3ry9i0	238	22	similar	similar	JJ
cord-104223-ht3ry9i0	238	23	to	to	IN
cord-104223-ht3ry9i0	238	24	that	that	DT
cord-104223-ht3ry9i0	238	25	proposed	propose	VBN
cord-104223-ht3ry9i0	238	26	for	for	IN
cord-104223-ht3ry9i0	238	27	lysosomal	lysosomal	JJ
cord-104223-ht3ry9i0	238	28	enzymes	enzyme	NNS
cord-104223-ht3ry9i0	238	29	.	.	.
cord-104223-ht3ry9i0	239	1	The	the	DT
cord-104223-ht3ry9i0	239	2	amino	amino	NN
cord-104223-ht3ry9i0	239	3	-	-	HYPH
cord-104223-ht3ry9i0	239	4	terminal	terminal	NN
cord-104223-ht3ry9i0	239	5	bag	bag	NN
cord-104223-ht3ry9i0	239	6	cell	cell	NN
cord-104223-ht3ry9i0	239	7	peptides	peptide	NNS
cord-104223-ht3ry9i0	239	8	act	act	VBP
cord-104223-ht3ry9i0	239	9	locally	locally	RB
cord-104223-ht3ry9i0	239	10	to	to	TO
cord-104223-ht3ry9i0	239	11	modulate	modulate	VB
cord-104223-ht3ry9i0	239	12	the	the	DT
cord-104223-ht3ry9i0	239	13	electrical	electrical	JJ
cord-104223-ht3ry9i0	239	14	activity	activity	NN
cord-104223-ht3ry9i0	239	15	of	of	IN
cord-104223-ht3ry9i0	239	16	abdominal	abdominal	JJ
cord-104223-ht3ry9i0	239	17	ganglion	ganglion	NN
cord-104223-ht3ry9i0	239	18	neurons	neuron	NNS
cord-104223-ht3ry9i0	239	19	and	and	CC
cord-104223-ht3ry9i0	239	20	in	in	IN
cord-104223-ht3ry9i0	239	21	an	an	DT
cord-104223-ht3ry9i0	239	22	autocrine	autocrine	JJ
cord-104223-ht3ry9i0	239	23	fashion	fashion	NN
cord-104223-ht3ry9i0	239	24	to	to	TO
cord-104223-ht3ry9i0	239	25	regulate	regulate	VB
cord-104223-ht3ry9i0	239	26	the	the	DT
cord-104223-ht3ry9i0	239	27	excitability	excitability	NN
cord-104223-ht3ry9i0	239	28	of	of	IN
cord-104223-ht3ry9i0	239	29	the	the	DT
cord-104223-ht3ry9i0	239	30	bag	bag	NN
cord-104223-ht3ry9i0	239	31	cells	cell	NNS
cord-104223-ht3ry9i0	240	1	(	(	-LRB-
cord-104223-ht3ry9i0	240	2	Rothman	Rothman	NNP
cord-104223-ht3ry9i0	240	3	et	et	NNP
cord-104223-ht3ry9i0	240	4	al	al	NNP
cord-104223-ht3ry9i0	240	5	.	.	.
cord-104223-ht3ry9i0	241	1	,	,	,
cord-104223-ht3ry9i0	241	2	1983a	1983a	CD
cord-104223-ht3ry9i0	241	3	;	;	:
cord-104223-ht3ry9i0	241	4	Kauer	Kauer	NNP
cord-104223-ht3ry9i0	241	5	et	et	NNP
cord-104223-ht3ry9i0	241	6	al	al	NNP
cord-104223-ht3ry9i0	241	7	.	.	.
cord-104223-ht3ry9i0	242	1	,	,	,
cord-104223-ht3ry9i0	242	2	1987	1987	CD
cord-104223-ht3ry9i0	242	3	;	;	:
cord-104223-ht3ry9i0	242	4	Brown	Brown	NNP
cord-104223-ht3ry9i0	242	5	and	and	CC
cord-104223-ht3ry9i0	242	6	Mayeri	Mayeri	NNP
cord-104223-ht3ry9i0	242	7	,	,	,
cord-104223-ht3ry9i0	242	8	1989	1989	CD
cord-104223-ht3ry9i0	242	9	)	)	-RRB-
cord-104223-ht3ry9i0	242	10	.	.	.
cord-104223-ht3ry9i0	243	1	The	the	DT
cord-104223-ht3ry9i0	243	2	carboxy	carboxy	JJ
cord-104223-ht3ry9i0	243	3	-	-	HYPH
cord-104223-ht3ry9i0	243	4	terminal	terminal	NN
cord-104223-ht3ry9i0	243	5	ELH	ELH	NNP
cord-104223-ht3ry9i0	243	6	acts	act	VBZ
cord-104223-ht3ry9i0	243	7	both	both	DT
cord-104223-ht3ry9i0	243	8	on	on	IN
cord-104223-ht3ry9i0	243	9	nearby	nearby	JJ
cord-104223-ht3ry9i0	243	10	neurons	neuron	NNS
cord-104223-ht3ry9i0	243	11	(	(	-LRB-
cord-104223-ht3ry9i0	243	12	Mayeri	Mayeri	NNP
cord-104223-ht3ry9i0	243	13	et	et	NNP
cord-104223-ht3ry9i0	243	14	al	al	NNP
cord-104223-ht3ry9i0	243	15	.	.	NNP
cord-104223-ht3ry9i0	243	16	,	,	,
cord-104223-ht3ry9i0	243	17	1985	1985	CD
cord-104223-ht3ry9i0	243	18	)	)	-RRB-
cord-104223-ht3ry9i0	243	19	and	and	CC
cord-104223-ht3ry9i0	243	20	through	through	IN
cord-104223-ht3ry9i0	243	21	the	the	DT
cord-104223-ht3ry9i0	243	22	circulation	circulation	NN
cord-104223-ht3ry9i0	243	23	at	at	IN
cord-104223-ht3ry9i0	243	24	peripheral	peripheral	JJ
cord-104223-ht3ry9i0	243	25	targets	target	NNS
cord-104223-ht3ry9i0	243	26	as	as	IN
cord-104223-ht3ry9i0	243	27	a	a	DT
cord-104223-ht3ry9i0	243	28	hormonal	hormonal	JJ
cord-104223-ht3ry9i0	243	29	substance	substance	NN
cord-104223-ht3ry9i0	243	30	(	(	-LRB-
cord-104223-ht3ry9i0	243	31	Kupfermann	Kupfermann	NNP
cord-104223-ht3ry9i0	243	32	,	,	,
cord-104223-ht3ry9i0	243	33	1967	1967	CD
cord-104223-ht3ry9i0	243	34	;	;	:
cord-104223-ht3ry9i0	243	35	R	r	NN
cord-104223-ht3ry9i0	243	36	~	~	NFP
cord-104223-ht3ry9i0	243	37	thman	thman	NNP
cord-104223-ht3ry9i0	243	38	et	et	FW
cord-104223-ht3ry9i0	243	39	al	al	NNP
cord-104223-ht3ry9i0	243	40	.	.	NNP
cord-104223-ht3ry9i0	243	41	,	,	,
cord-104223-ht3ry9i0	243	42	1983b	1983b	CD
cord-104223-ht3ry9i0	243	43	)	)	-RRB-
cord-104223-ht3ry9i0	243	44	.	.	.
cord-104223-ht3ry9i0	244	1	Thus	thus	RB
cord-104223-ht3ry9i0	244	2	,	,	,
cord-104223-ht3ry9i0	244	3	while	while	IN
cord-104223-ht3ry9i0	244	4	the	the	DT
cord-104223-ht3ry9i0	244	5	polyprotein	polyprotein	NNP
cord-104223-ht3ry9i0	244	6	motif	motif	NN
cord-104223-ht3ry9i0	244	7	ensures	ensure	VBZ
cord-104223-ht3ry9i0	244	8	cosynthesis	cosynthesis	NNP
cord-104223-ht3ry9i0	244	9	,	,	,
cord-104223-ht3ry9i0	244	10	the	the	DT
cord-104223-ht3ry9i0	244	11	relative	relative	JJ
cord-104223-ht3ry9i0	244	12	levels	level	NNS
cord-104223-ht3ry9i0	244	13	of	of	IN
cord-104223-ht3ry9i0	244	14	these	these	DT
cord-104223-ht3ry9i0	244	15	two	two	CD
cord-104223-ht3ry9i0	244	16	sets	set	NNS
cord-104223-ht3ry9i0	244	17	of	of	IN
cord-104223-ht3ry9i0	244	18	substances	substance	NNS
cord-104223-ht3ry9i0	244	19	are	be	VBP
cord-104223-ht3ry9i0	244	20	regulated	regulate	VBN
cord-104223-ht3ry9i0	244	21	by	by	IN
cord-104223-ht3ry9i0	244	22	the	the	DT
cord-104223-ht3ry9i0	244	23	proteolytic	proteolytic	JJ
cord-104223-ht3ry9i0	244	24	cleavage	cleavage	NN
cord-104223-ht3ry9i0	244	25	,	,	,
cord-104223-ht3ry9i0	244	26	packaging	packaging	NN
cord-104223-ht3ry9i0	244	27	,	,	,
cord-104223-ht3ry9i0	244	28	and	and	CC
cord-104223-ht3ry9i0	244	29	targeting	target	VBG
cord-104223-ht3ry9i0	244	30	described	describe	VBN
cord-104223-ht3ry9i0	244	31	above	above	RB
cord-104223-ht3ry9i0	244	32	.	.	.
cord-104223-ht3ry9i0	245	1	Recent	recent	JJ
cord-104223-ht3ry9i0	245	2	studies	study	NNS
cord-104223-ht3ry9i0	245	3	indicate	indicate	VBP
cord-104223-ht3ry9i0	245	4	that	that	IN
cord-104223-ht3ry9i0	245	5	non	non	JJ
cord-104223-ht3ry9i0	245	6	-	-	JJ
cord-104223-ht3ry9i0	245	7	ELH	ELH	NNP
cord-104223-ht3ry9i0	245	8	precursor	precursor	NN
cord-104223-ht3ry9i0	245	9	-	-	HYPH
cord-104223-ht3ry9i0	245	10	related	relate	VBN
cord-104223-ht3ry9i0	245	11	bag	bag	NN
cord-104223-ht3ry9i0	245	12	cell	cell	NN
cord-104223-ht3ry9i0	245	13	vesicle	vesicle	NN
cord-104223-ht3ry9i0	245	14	proteins	protein	NNS
cord-104223-ht3ry9i0	245	15	are	be	VBP
cord-104223-ht3ry9i0	245	16	also	also	RB
cord-104223-ht3ry9i0	245	17	selectively	selectively	RB
cord-104223-ht3ry9i0	245	18	sorted	sort	VBN
cord-104223-ht3ry9i0	245	19	)	)	-RRB-
cord-104223-ht3ry9i0	245	20	.	.	.
cord-104223-ht3ry9i0	246	1	These	these	DT
cord-104223-ht3ry9i0	246	2	latter	latter	JJ
cord-104223-ht3ry9i0	246	3	molecules	molecule	NNS
cord-104223-ht3ry9i0	246	4	may	may	MD
cord-104223-ht3ry9i0	246	5	play	play	VB
cord-104223-ht3ry9i0	246	6	a	a	DT
cord-104223-ht3ry9i0	246	7	role	role	NN
cord-104223-ht3ry9i0	246	8	in	in	IN
cord-104223-ht3ry9i0	246	9	selective	selective	JJ
cord-104223-ht3ry9i0	246	10	transport	transport	NN
cord-104223-ht3ry9i0	246	11	or	or	CC
cord-104223-ht3ry9i0	246	12	release	release	NN
cord-104223-ht3ry9i0	246	13	of	of	IN
cord-104223-ht3ry9i0	246	14	different	different	JJ
cord-104223-ht3ry9i0	246	15	vesicle	vesicle	NN
cord-104223-ht3ry9i0	246	16	types	type	NNS
cord-104223-ht3ry9i0	246	17	.	.	.
cord-104223-ht3ry9i0	247	1	Other	other	JJ
cord-104223-ht3ry9i0	247	2	neurons	neuron	NNS
cord-104223-ht3ry9i0	247	3	that	that	WDT
cord-104223-ht3ry9i0	247	4	express	express	VBP
cord-104223-ht3ry9i0	247	5	the	the	DT
cord-104223-ht3ry9i0	247	6	ELH	ELH	NNP
cord-104223-ht3ry9i0	247	7	prohormone	prohormone	NN
cord-104223-ht3ry9i0	247	8	(	(	-LRB-
cord-104223-ht3ry9i0	247	9	 	 	_SP
cord-104223-ht3ry9i0	247	10	A	a	DT
cord-104223-ht3ry9i0	247	11	view	view	NN
cord-104223-ht3ry9i0	247	12	of	of	IN
cord-104223-ht3ry9i0	247	13	acidic	acidic	JJ
cord-104223-ht3ry9i0	247	14	intracellular	intracellular	JJ
cord-104223-ht3ry9i0	247	15	compartments	compartment	NNS
cord-104223-ht3ry9i0	247	16	Activation	activation	NN
cord-104223-ht3ry9i0	247	17	of	of	IN
cord-104223-ht3ry9i0	247	18	neurosecretory	neurosecretory	NNP
cord-104223-ht3ry9i0	247	19	cells	cell	NNS
cord-104223-ht3ry9i0	247	20	enhances	enhance	VBZ
cord-104223-ht3ry9i0	247	21	the	the	DT
cord-104223-ht3ry9i0	247	22	synthesis	synthesis	NN
cord-104223-ht3ry9i0	247	23	of	of	IN
cord-104223-ht3ry9i0	247	24	secretory	secretory	JJ
cord-104223-ht3ry9i0	247	25	protein	protein	NN
cord-104223-ht3ry9i0	247	26	Positive	positive	JJ
cord-104223-ht3ry9i0	247	27	feedback	feedback	NN
cord-104223-ht3ry9i0	247	28	by	by	IN
cord-104223-ht3ry9i0	247	29	autoexcitatory	autoexcitatory	JJ
cord-104223-ht3ry9i0	247	30	neuroendocrine	neuroendocrine	JJ
cord-104223-ht3ry9i0	247	31	bag	bag	NN
cord-104223-ht3ry9i0	247	32	cells	cell	NNS
cord-104223-ht3ry9i0	247	33	of	of	IN
cord-104223-ht3ry9i0	247	34	Aplysia	Aplysia	NNP
cord-104223-ht3ry9i0	247	35	Constitutive	Constitutive	NNP
cord-104223-ht3ry9i0	247	36	and	and	CC
cord-104223-ht3ry9i0	247	37	regulated	regulated	JJ
cord-104223-ht3ry9i0	247	38	secretion	secretion	NN
cord-104223-ht3ry9i0	247	39	of	of	IN
cord-104223-ht3ry9i0	247	40	proteins	protein	NNS
cord-104223-ht3ry9i0	247	41	Coated	coat	VBN
cord-104223-ht3ry9i0	247	42	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	247	43	from	from	IN
cord-104223-ht3ry9i0	247	44	rat	rat	NN
cord-104223-ht3ry9i0	247	45	liver	liver	NN
cord-104223-ht3ry9i0	247	46	and	and	CC
cord-104223-ht3ry9i0	247	47	calf	calf	NN
cord-104223-ht3ry9i0	247	48	brain	brain	NN
cord-104223-ht3ry9i0	247	49	contain	contain	VBP
cord-104223-ht3ry9i0	247	50	lysosomal	lysosomal	JJ
cord-104223-ht3ry9i0	247	51	enzymes	enzyme	NNS
cord-104223-ht3ry9i0	247	52	bound	bind	VBN
cord-104223-ht3ry9i0	247	53	to	to	IN
cord-104223-ht3ry9i0	247	54	mannose-6-phosphate	mannose-6-phosphate	JJ
cord-104223-ht3ry9i0	247	55	receptors	receptor	NNS
cord-104223-ht3ry9i0	248	1	A	a	DT
cord-104223-ht3ry9i0	248	2	common	common	JJ
cord-104223-ht3ry9i0	248	3	source	source	NN
cord-104223-ht3ry9i0	248	4	of	of	IN
cord-104223-ht3ry9i0	248	5	ditficulty	ditficulty	NN
cord-104223-ht3ry9i0	248	6	in	in	IN
cord-104223-ht3ry9i0	248	7	high	high	JJ
cord-104223-ht3ry9i0	248	8	resolution	resolution	NN
cord-104223-ht3ry9i0	248	9	autoradiography	autoradiography	NN
cord-104223-ht3ry9i0	248	10	High	high	JJ
cord-104223-ht3ry9i0	248	11	resolution	resolution	NN
cord-104223-ht3ry9i0	248	12	autoradiography	autoradiography	NN
cord-104223-ht3ry9i0	248	13	Two	two	CD
cord-104223-ht3ry9i0	248	14	neuronal	neuronal	JJ
cord-104223-ht3ry9i0	248	15	populations	population	NNS
cord-104223-ht3ry9i0	248	16	in	in	IN
cord-104223-ht3ry9i0	248	17	the	the	DT
cord-104223-ht3ry9i0	248	18	head	head	NN
cord-104223-ht3ry9i0	248	19	ganglia	ganglion	NNS
cord-104223-ht3ry9i0	248	20	of	of	IN
cord-104223-ht3ry9i0	248	21	Aplysia	Aplysia	NNP
cord-104223-ht3ry9i0	248	22	californica	californica	NNP
cord-104223-ht3ry9i0	248	23	with	with	IN
cord-104223-ht3ry9i0	248	24	egg	egg	NN
cord-104223-ht3ry9i0	248	25	-	-	HYPH
cord-104223-ht3ry9i0	248	26	laying	lay	VBG
cord-104223-ht3ry9i0	248	27	hormone	hormone	NN
cord-104223-ht3ry9i0	248	28	-	-	HYPH
cord-104223-ht3ry9i0	248	29	like	like	JJ
cord-104223-ht3ry9i0	248	30	immunoreactivity	immunoreactivity	NNP
cord-104223-ht3ry9i0	248	31	Molecular	Molecular	NNP
cord-104223-ht3ry9i0	248	32	sorting	sort	VBG
cord-104223-ht3ry9i0	248	33	in	in	IN
cord-104223-ht3ry9i0	248	34	the	the	DT
cord-104223-ht3ry9i0	248	35	secretory	secretory	JJ
cord-104223-ht3ry9i0	248	36	pathway	pathway	NN
cord-104223-ht3ry9i0	248	37	Effects	effect	NNS
cord-104223-ht3ry9i0	248	38	of	of	IN
cord-104223-ht3ry9i0	248	39	monensin	monensin	NNP
cord-104223-ht3ry9i0	248	40	on	on	IN
cord-104223-ht3ry9i0	248	41	the	the	DT
cord-104223-ht3ry9i0	248	42	processing	processing	NN
cord-104223-ht3ry9i0	248	43	of	of	IN
cord-104223-ht3ry9i0	248	44	proopiomelanocortin	proopiomelanocortin	NNS
cord-104223-ht3ry9i0	248	45	in	in	IN
cord-104223-ht3ry9i0	248	46	the	the	DT
cord-104223-ht3ry9i0	248	47	intermediate	intermediate	JJ
cord-104223-ht3ry9i0	248	48	lobe	lobe	NN
cord-104223-ht3ry9i0	248	49	of	of	IN
cord-104223-ht3ry9i0	248	50	the	the	DT
cord-104223-ht3ry9i0	248	51	rat	rat	NN
cord-104223-ht3ry9i0	248	52	pituitary	pituitary	NN
cord-104223-ht3ry9i0	248	53	Intranrganellar	intranrganellar	JJ
cord-104223-ht3ry9i0	248	54	calcium	calcium	NN
cord-104223-ht3ry9i0	248	55	and	and	CC
cord-104223-ht3ry9i0	248	56	pH	pH	NNP
cord-104223-ht3ry9i0	248	57	control	control	NNP
cord-104223-ht3ry9i0	248	58	proinsulin	proinsulin	NNP
cord-104223-ht3ry9i0	248	59	cleavage	cleavage	NN
cord-104223-ht3ry9i0	248	60	in	in	IN
cord-104223-ht3ry9i0	248	61	the	the	DT
cord-104223-ht3ry9i0	248	62	pancreatic	pancreatic	NN
cord-104223-ht3ry9i0	248	63	B	b	NN
cord-104223-ht3ry9i0	248	64	cell	cell	NN
cord-104223-ht3ry9i0	248	65	via	via	IN
cord-104223-ht3ry9i0	248	66	two	two	CD
cord-104223-ht3ry9i0	248	67	distinct	distinct	JJ
cord-104223-ht3ry9i0	248	68	site	site	NN
cord-104223-ht3ry9i0	248	69	-	-	HYPH
cord-104223-ht3ry9i0	248	70	specific	specific	JJ
cord-104223-ht3ry9i0	248	71	endopeptidases	endopeptidase	NNS
cord-104223-ht3ry9i0	248	72	Multiple	multiple	JJ
cord-104223-ht3ry9i0	248	73	neuropeptides	neuropeptide	NNS
cord-104223-ht3ry9i0	248	74	derived	derive	VBN
cord-104223-ht3ry9i0	248	75	from	from	IN
cord-104223-ht3ry9i0	248	76	a	a	DT
cord-104223-ht3ry9i0	248	77	common	common	JJ
cord-104223-ht3ry9i0	248	78	precursor	precursor	NN
cord-104223-ht3ry9i0	248	79	are	be	VBP
cord-104223-ht3ry9i0	248	80	differentially	differentially	RB
cord-104223-ht3ry9i0	248	81	packaged	package	VBN
cord-104223-ht3ry9i0	248	82	and	and	CC
cord-104223-ht3ry9i0	248	83	transported	transport	VBN
cord-104223-ht3ry9i0	248	84	Osmium	osmium	NN
cord-104223-ht3ry9i0	248	85	impregnation	impregnation	NN
cord-104223-ht3ry9i0	248	86	of	of	IN
cord-104223-ht3ry9i0	248	87	the	the	DT
cord-104223-ht3ry9i0	248	88	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	248	89	apparatus	apparatus	NN
cord-104223-ht3ry9i0	249	1	In	in	IN
cord-104223-ht3ry9i0	249	2	cow	cow	NN
cord-104223-ht3ry9i0	249	3	anterior	anterior	JJ
cord-104223-ht3ry9i0	249	4	pituitary	pituitary	NN
cord-104223-ht3ry9i0	249	5	,	,	,
cord-104223-ht3ry9i0	249	6	growth	growth	NN
cord-104223-ht3ry9i0	249	7	hormone	hormone	NN
cord-104223-ht3ry9i0	249	8	and	and	CC
cord-104223-ht3ry9i0	249	9	prolactin	prolactin	NN
cord-104223-ht3ry9i0	249	10	can	can	MD
cord-104223-ht3ry9i0	249	11	be	be	VB
cord-104223-ht3ry9i0	249	12	packaged	package	VBN
cord-104223-ht3ry9i0	249	13	into	into	IN
cord-104223-ht3ry9i0	249	14	separate	separate	JJ
cord-104223-ht3ry9i0	249	15	granules	granule	NNS
cord-104223-ht3ry9i0	249	16	in	in	IN
cord-104223-ht3ry9i0	249	17	the	the	DT
cord-104223-ht3ry9i0	249	18	same	same	JJ
cord-104223-ht3ry9i0	249	19	cell	cell	NN
cord-104223-ht3ry9i0	249	20	Nearophysin	Nearophysin	NNP
cord-104223-ht3ry9i0	249	21	biosynthesis	biosynthesis	NN
cord-104223-ht3ry9i0	249	22	:	:	:
cord-104223-ht3ry9i0	249	23	conversion	conversion	NN
cord-104223-ht3ry9i0	249	24	of	of	IN
cord-104223-ht3ry9i0	249	25	a	a	DT
cord-104223-ht3ry9i0	249	26	putative	putative	JJ
cord-104223-ht3ry9i0	249	27	precursor	precursor	NN
cord-104223-ht3ry9i0	249	28	during	during	IN
cord-104223-ht3ry9i0	249	29	axonai	axonai	NNP
cord-104223-ht3ry9i0	249	30	transport	transport	NN
cord-104223-ht3ry9i0	250	1	The	the	DT
cord-104223-ht3ry9i0	250	2	trans	trans	JJ
cord-104223-ht3ry9i0	250	3	-	-	JJ
cord-104223-ht3ry9i0	250	4	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	250	5	network	network	NN
cord-104223-ht3ry9i0	250	6	:	:	:
cord-104223-ht3ry9i0	250	7	sorting	sort	VBG
cord-104223-ht3ry9i0	250	8	atthe	atthe	JJ
cord-104223-ht3ry9i0	250	9	exit	exit	NN
cord-104223-ht3ry9i0	250	10	site	site	NN
cord-104223-ht3ry9i0	250	11	of	of	IN
cord-104223-ht3ry9i0	250	12	the	the	DT
cord-104223-ht3ry9i0	250	13	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	250	14	complex	complex	JJ
cord-104223-ht3ry9i0	250	15	Dissection	dissection	NN
cord-104223-ht3ry9i0	250	16	of	of	IN
cord-104223-ht3ry9i0	250	17	the	the	DT
cord-104223-ht3ry9i0	250	18	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	250	19	complex	complex	NN
cord-104223-ht3ry9i0	250	20	.	.	.
cord-104223-ht3ry9i0	251	1	I.	I.	NNP
cord-104223-ht3ry9i0	251	2	Moneasin	Moneasin	NNP
cord-104223-ht3ry9i0	251	3	inhibits	inhibit	VBZ
cord-104223-ht3ry9i0	251	4	the	the	DT
cord-104223-ht3ry9i0	251	5	transport	transport	NN
cord-104223-ht3ry9i0	251	6	of	of	IN
cord-104223-ht3ry9i0	251	7	viral	viral	JJ
cord-104223-ht3ry9i0	251	8	membrane	membrane	NN
cord-104223-ht3ry9i0	251	9	proteins	protein	NNS
cord-104223-ht3ry9i0	251	10	from	from	IN
cord-104223-ht3ry9i0	251	11	medialto	medialto	NNP
cord-104223-ht3ry9i0	251	12	trans	trans	NNP
cord-104223-ht3ry9i0	251	13	-	-	NNP
cord-104223-ht3ry9i0	251	14	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	251	15	cisternae	cisternae	NN
cord-104223-ht3ry9i0	251	16	in	in	IN
cord-104223-ht3ry9i0	251	17	baby	baby	NN
cord-104223-ht3ry9i0	251	18	hamster	hamster	NN
cord-104223-ht3ry9i0	251	19	kidney	kidney	NN
cord-104223-ht3ry9i0	251	20	cells	cell	NNS
cord-104223-ht3ry9i0	251	21	infected	infect	VBN
cord-104223-ht3ry9i0	251	22	with	with	IN
cord-104223-ht3ry9i0	251	23	semliki	semliki	NNP
cord-104223-ht3ry9i0	251	24	forest	forest	NNP
cord-104223-ht3ry9i0	251	25	virus	virus	NNP
cord-104223-ht3ry9i0	252	1	The	the	DT
cord-104223-ht3ry9i0	252	2	mannose	mannose	NN
cord-104223-ht3ry9i0	252	3	6-phosphate	6-phosphate	NN
cord-104223-ht3ry9i0	252	4	receptor	receptor	NN
cord-104223-ht3ry9i0	252	5	and	and	CC
cord-104223-ht3ry9i0	252	6	the	the	DT
cord-104223-ht3ry9i0	252	7	biogenesis	biogenesis	NN
cord-104223-ht3ry9i0	252	8	of	of	IN
cord-104223-ht3ry9i0	252	9	lysosomes	lysosome	NNS
cord-104223-ht3ry9i0	252	10	The	the	DT
cord-104223-ht3ry9i0	252	11	role	role	NN
cord-104223-ht3ry9i0	252	12	of	of	IN
cord-104223-ht3ry9i0	252	13	the	the	DT
cord-104223-ht3ry9i0	252	14	Goigi	Goigi	NNP
cord-104223-ht3ry9i0	252	15	apparatus	apparatus	NN
cord-104223-ht3ry9i0	252	16	and	and	CC
cord-104223-ht3ry9i0	252	17	GERL	gerl	NN
cord-104223-ht3ry9i0	252	18	in	in	IN
cord-104223-ht3ry9i0	252	19	secretory	secretory	JJ
cord-104223-ht3ry9i0	252	20	granule	granule	NN
cord-104223-ht3ry9i0	252	21	formation	formation	NN
cord-104223-ht3ry9i0	252	22	in	in	IN
cord-104223-ht3ry9i0	252	23	acinar	acinar	JJ
cord-104223-ht3ry9i0	252	24	cells	cell	NNS
cord-104223-ht3ry9i0	252	25	of	of	IN
cord-104223-ht3ry9i0	252	26	the	the	DT
cord-104223-ht3ry9i0	252	27	~	~	NFP
cord-104223-ht3ry9i0	252	28	rat	rat	NNP
cord-104223-ht3ry9i0	252	29	exorbital	exorbital	NNP
cord-104223-ht3ry9i0	252	30	lacrimar	lacrimar	NNP
cord-104223-ht3ry9i0	252	31	gland	gland	NN
cord-104223-ht3ry9i0	252	32	Sorting	sorting	NN
cord-104223-ht3ry9i0	252	33	of	of	IN
cord-104223-ht3ry9i0	252	34	three	three	CD
cord-104223-ht3ry9i0	252	35	secretory	secretory	JJ
cord-104223-ht3ry9i0	252	36	proteins	protein	NNS
cord-104223-ht3ry9i0	252	37	to	to	IN
cord-104223-ht3ry9i0	252	38	distinct	distinct	JJ
cord-104223-ht3ry9i0	252	39	secretory	secretory	JJ
cord-104223-ht3ry9i0	252	40	granules	granule	NNS
cord-104223-ht3ry9i0	252	41	in	in	IN
cord-104223-ht3ry9i0	252	42	acidophilic	acidophilic	NNP
cord-104223-ht3ry9i0	252	43	ceils	ceil	NNS
cord-104223-ht3ry9i0	252	44	of	of	IN
cord-104223-ht3ry9i0	252	45	cow	cow	NN
cord-104223-ht3ry9i0	252	46	anterior	anterior	JJ
cord-104223-ht3ry9i0	252	47	pituitary	pituitary	JJ
cord-104223-ht3ry9i0	252	48	Vesicular	Vesicular	NNP
cord-104223-ht3ry9i0	252	49	stomatitis	stomatitis	NN
cord-104223-ht3ry9i0	252	50	virus	virus	NN
cord-104223-ht3ry9i0	252	51	and	and	CC
cord-104223-ht3ry9i0	252	52	Sindbis	Sindbis	NNP
cord-104223-ht3ry9i0	252	53	virus	virus	NN
cord-104223-ht3ry9i0	252	54	glycoproteins	glycoprotein	NNS
cord-104223-ht3ry9i0	252	55	transport	transport	NN
cord-104223-ht3ry9i0	252	56	to	to	IN
cord-104223-ht3ry9i0	252	57	the	the	DT
cord-104223-ht3ry9i0	252	58	cell	cell	NN
cord-104223-ht3ry9i0	252	59	surface	surface	NN
cord-104223-ht3ry9i0	252	60	is	be	VBZ
cord-104223-ht3ry9i0	252	61	inhibited	inhibit	VBN
cord-104223-ht3ry9i0	252	62	by	by	IN
cord-104223-ht3ry9i0	252	63	ionophores	ionophores	NNP
cord-104223-ht3ry9i0	252	64	Alpha	Alpha	NNP
cord-104223-ht3ry9i0	252	65	bag	bag	NN
cord-104223-ht3ry9i0	252	66	cell	cell	NN
cord-104223-ht3ry9i0	252	67	peptide	peptide	NN
cord-104223-ht3ry9i0	252	68	directly	directly	RB
cord-104223-ht3ry9i0	252	69	modulates	modulate	VBZ
cord-104223-ht3ry9i0	252	70	the	the	DT
cord-104223-ht3ry9i0	252	71	excitability	excitability	NN
cord-104223-ht3ry9i0	252	72	of	of	IN
cord-104223-ht3ry9i0	252	73	the	the	DT
cord-104223-ht3ry9i0	252	74	neurons	neuron	NNS
cord-104223-ht3ry9i0	252	75	that	that	WDT
cord-104223-ht3ry9i0	252	76	release	release	VBP
cord-104223-ht3ry9i0	252	77	it	-PRON-	PRP
cord-104223-ht3ry9i0	252	78	Pathways	Pathways	NNPS
cord-104223-ht3ry9i0	252	79	of	of	IN
cord-104223-ht3ry9i0	252	80	protein	protein	NN
cord-104223-ht3ry9i0	252	81	secretion	secretion	NN
cord-104223-ht3ry9i0	252	82	in	in	IN
cord-104223-ht3ry9i0	252	83	eukaryotes	eukaryote	NNS
cord-104223-ht3ry9i0	252	84	Localization	Localization	NNP
cord-104223-ht3ry9i0	252	85	of	of	IN
cord-104223-ht3ry9i0	252	86	Aplysia	Aplysia	NNP
cord-104223-ht3ry9i0	252	87	neurosecretory	neurosecretory	NN
cord-104223-ht3ry9i0	252	88	peptides	peptide	NNS
cord-104223-ht3ry9i0	252	89	to	to	IN
cord-104223-ht3ry9i0	252	90	multiple	multiple	JJ
cord-104223-ht3ry9i0	252	91	populations	population	NNS
cord-104223-ht3ry9i0	252	92	of	of	IN
cord-104223-ht3ry9i0	252	93	dense	dense	JJ
cord-104223-ht3ry9i0	252	94	core	core	NN
cord-104223-ht3ry9i0	252	95	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	252	96	,	,	,
cord-104223-ht3ry9i0	252	97	jr	jr	NNP
cord-104223-ht3ry9i0	252	98	Large	Large	NNP
cord-104223-ht3ry9i0	252	99	dense	dense	JJ
cord-104223-ht3ry9i0	252	100	cored	cored	JJ
cord-104223-ht3ry9i0	252	101	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	252	102	are	be	VBP
cord-104223-ht3ry9i0	252	103	enriched	enrich	VBN
cord-104223-ht3ry9i0	252	104	in	in	IN
cord-104223-ht3ry9i0	252	105	neuropeptide	neuropeptide	NN
cord-104223-ht3ry9i0	252	106	processing	processing	NN
cord-104223-ht3ry9i0	252	107	intermediates	intermediate	NNS
cord-104223-ht3ry9i0	252	108	in	in	IN
cord-104223-ht3ry9i0	252	109	the	the	DT
cord-104223-ht3ry9i0	252	110	Aplysia	Aplysia	NNP
cord-104223-ht3ry9i0	252	111	bag	bag	NN
cord-104223-ht3ry9i0	252	112	cells	cell	VBZ
cord-104223-ht3ry9i0	252	113	Stimulation	stimulation	NN
cord-104223-ht3ry9i0	252	114	of	of	IN
cord-104223-ht3ry9i0	252	115	egg	egg	NN
cord-104223-ht3ry9i0	252	116	laying	laying	NN
cord-104223-ht3ry9i0	252	117	:	:	:
cord-104223-ht3ry9i0	252	118	possible	possible	JJ
cord-104223-ht3ry9i0	252	119	neurocndocrine	neurocndocrine	JJ
cord-104223-ht3ry9i0	252	120	function	function	NN
cord-104223-ht3ry9i0	252	121	of	of	IN
cord-104223-ht3ry9i0	252	122	bag	bag	NN
cord-104223-ht3ry9i0	252	123	cells	cell	NNS
cord-104223-ht3ry9i0	252	124	of	of	IN
cord-104223-ht3ry9i0	253	1	abdominal	abdominal	JJ
cord-104223-ht3ry9i0	253	2	ganglia	ganglion	NNS
cord-104223-ht3ry9i0	253	3	ofAplysia	ofAplysia	NNP
cord-104223-ht3ry9i0	254	1	californica	californica	NNP
cord-104223-ht3ry9i0	254	2	Proteolysis	Proteolysis	NNP
cord-104223-ht3ry9i0	254	3	in	in	IN
cord-104223-ht3ry9i0	254	4	neuropeptide	neuropeptide	NN
cord-104223-ht3ry9i0	254	5	processing	processing	NN
cord-104223-ht3ry9i0	254	6	and	and	CC
cord-104223-ht3ry9i0	254	7	other	other	JJ
cord-104223-ht3ry9i0	254	8	neural	neural	JJ
cord-104223-ht3ry9i0	254	9	functions	function	NNS
cord-104223-ht3ry9i0	255	1	Nonsynaptic	nonsynaptic	JJ
cord-104223-ht3ry9i0	255	2	characteristics	characteristic	NNS
cord-104223-ht3ry9i0	255	3	of	of	IN
cord-104223-ht3ry9i0	255	4	neurotransmission	neurotransmission	NN
cord-104223-ht3ry9i0	255	5	mediated	mediate	VBN
cord-104223-ht3ry9i0	255	6	by	by	IN
cord-104223-ht3ry9i0	255	7	egglaying	egglaye	VBG
cord-104223-ht3ry9i0	255	8	hormone	hormone	NN
cord-104223-ht3ry9i0	255	9	in	in	IN
cord-104223-ht3ry9i0	255	10	the	the	DT
cord-104223-ht3ry9i0	255	11	abdominal	abdominal	JJ
cord-104223-ht3ry9i0	255	12	ganglion	ganglion	NN
cord-104223-ht3ry9i0	255	13	ofAplysia	ofAplysia	NNP
cord-104223-ht3ry9i0	255	14	In	in	IN
cord-104223-ht3ry9i0	255	15	situ	situ	JJ
cord-104223-ht3ry9i0	255	16	hybridization	hybridization	NN
cord-104223-ht3ry9i0	255	17	to	to	TO
cord-104223-ht3ry9i0	255	18	study	study	VB
cord-104223-ht3ry9i0	255	19	the	the	DT
cord-104223-ht3ry9i0	255	20	origin	origin	NN
cord-104223-ht3ry9i0	255	21	and	and	CC
cord-104223-ht3ry9i0	255	22	fate	fate	NN
cord-104223-ht3ry9i0	255	23	of	of	IN
cord-104223-ht3ry9i0	255	24	identified	identify	VBN
cord-104223-ht3ry9i0	255	25	neurons	neuron	NNS
cord-104223-ht3ry9i0	255	26	Maximum	Maximum	NNP
cord-104223-ht3ry9i0	255	27	-	-	HYPH
cord-104223-ht3ry9i0	255	28	likelihood	likelihood	NN
cord-104223-ht3ry9i0	255	29	estimation	estimation	NN
cord-104223-ht3ry9i0	255	30	applied	apply	VBN
cord-104223-ht3ry9i0	255	31	to	to	IN
cord-104223-ht3ry9i0	255	32	electron	electron	NN
cord-104223-ht3ry9i0	255	33	microscopic	microscopic	JJ
cord-104223-ht3ry9i0	255	34	autoradiography	autoradiography	NN
cord-104223-ht3ry9i0	255	35	Proteolytic	Proteolytic	NNP
cord-104223-ht3ry9i0	255	36	processing	processing	NN
cord-104223-ht3ry9i0	255	37	of	of	IN
cord-104223-ht3ry9i0	255	38	the	the	DT
cord-104223-ht3ry9i0	255	39	Aplysia	Aplysia	NNP
cord-104223-ht3ry9i0	255	40	egg	egg	NN
cord-104223-ht3ry9i0	255	41	-	-	HYPH
cord-104223-ht3ry9i0	255	42	laying	lay	VBG
cord-104223-ht3ry9i0	255	43	hormone	hormone	NN
cord-104223-ht3ry9i0	255	44	and	and	CC
cord-104223-ht3ry9i0	255	45	R3	R3	NNP
cord-104223-ht3ry9i0	255	46	-	-	HYPH
cord-104223-ht3ry9i0	255	47	14	14	CD
cord-104223-ht3ry9i0	255	48	neuropeptide	neuropeptide	NN
cord-104223-ht3ry9i0	255	49	precursors	precursor	NNS
cord-104223-ht3ry9i0	255	50	Processing	process	VBG
cord-104223-ht3ry9i0	255	51	of	of	IN
cord-104223-ht3ry9i0	255	52	the	the	DT
cord-104223-ht3ry9i0	255	53	ELH	ELH	NNP
cord-104223-ht3ry9i0	255	54	precursor	precursor	NN
cord-104223-ht3ry9i0	255	55	in	in	IN
cord-104223-ht3ry9i0	255	56	the	the	DT
cord-104223-ht3ry9i0	255	57	bag	bag	NN
cord-104223-ht3ry9i0	255	58	cell	cell	NN
cord-104223-ht3ry9i0	255	59	neurons	neuron	NNS
cord-104223-ht3ry9i0	255	60	of	of	IN
cord-104223-ht3ry9i0	255	61	Aplysia	Aplysia	NNP
cord-104223-ht3ry9i0	255	62	Goigi	Goigi	NNP
cord-104223-ht3ry9i0	255	63	apparatus	apparatus	NN
cord-104223-ht3ry9i0	255	64	,	,	,
cord-104223-ht3ry9i0	255	65	GERL	GERL	NNP
cord-104223-ht3ry9i0	255	66	,	,	,
cord-104223-ht3ry9i0	255	67	and	and	CC
cord-104223-ht3ry9i0	255	68	lysosomes	lysosome	NNS
cord-104223-ht3ry9i0	255	69	in	in	IN
cord-104223-ht3ry9i0	255	70	neurons	neuron	NNS
cord-104223-ht3ry9i0	255	71	of	of	IN
cord-104223-ht3ry9i0	255	72	rat	rat	NN
cord-104223-ht3ry9i0	255	73	dorsal	dorsal	JJ
cord-104223-ht3ry9i0	255	74	root	root	NN
cord-104223-ht3ry9i0	255	75	ganglia	ganglion	NNS
cord-104223-ht3ry9i0	255	76	studied	study	VBN
cord-104223-ht3ry9i0	255	77	by	by	IN
cord-104223-ht3ry9i0	255	78	thick	thick	JJ
cord-104223-ht3ry9i0	255	79	section	section	NN
cord-104223-ht3ry9i0	255	80	and	and	CC
cord-104223-ht3ry9i0	255	81	thin	thin	JJ
cord-104223-ht3ry9i0	255	82	section	section	NN
cord-104223-ht3ry9i0	255	83	cytochemistry	cytochemistry	NN
cord-104223-ht3ry9i0	255	84	Perrelet	Perrelet	NNP
cord-104223-ht3ry9i0	255	85	.	.	.
cord-104223-ht3ry9i0	256	1	1984	1984	CD
cord-104223-ht3ry9i0	256	2	.	.	.
cord-104223-ht3ry9i0	257	1	A	a	DT
cord-104223-ht3ry9i0	257	2	clathrin	clathrin	NN
cord-104223-ht3ry9i0	257	3	-	-	HYPH
cord-104223-ht3ry9i0	257	4	coated	coat	VBN
cord-104223-ht3ry9i0	257	5	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	257	6	-	-	HYPH
cord-104223-ht3ry9i0	257	7	related	relate	VBN
cord-104223-ht3ry9i0	257	8	compartment	compartment	NN
cord-104223-ht3ry9i0	257	9	of	of	IN
cord-104223-ht3ry9i0	257	10	the	the	DT
cord-104223-ht3ry9i0	257	11	insulin	insulin	NN
cord-104223-ht3ry9i0	257	12	secreting	secrete	VBG
cord-104223-ht3ry9i0	257	13	cell	cell	NN
cord-104223-ht3ry9i0	257	14	accumulates	accumulate	VBZ
cord-104223-ht3ry9i0	257	15	proinsulin	proinsulin	NNP
cord-104223-ht3ry9i0	257	16	in	in	IN
cord-104223-ht3ry9i0	257	17	the	the	DT
cord-104223-ht3ry9i0	257	18	presence	presence	NN
cord-104223-ht3ry9i0	257	19	of	of	IN
cord-104223-ht3ry9i0	257	20	monensin	monensin	NNP
cord-104223-ht3ry9i0	257	21	Proteolytic	Proteolytic	NNP
cord-104223-ht3ry9i0	257	22	maturation	maturation	NN
cord-104223-ht3ry9i0	257	23	of	of	IN
cord-104223-ht3ry9i0	257	24	insulin	insulin	NN
cord-104223-ht3ry9i0	257	25	is	be	VBZ
cord-104223-ht3ry9i0	257	26	a	a	DT
cord-104223-ht3ry9i0	257	27	post	post	JJ
cord-104223-ht3ry9i0	257	28	-	-	JJ
cord-104223-ht3ry9i0	257	29	Golgi	golgi	JJ
cord-104223-ht3ry9i0	257	30	event	event	NN
cord-104223-ht3ry9i0	257	31	which	which	WDT
cord-104223-ht3ry9i0	257	32	occurs	occur	VBZ
cord-104223-ht3ry9i0	257	33	in	in	IN
cord-104223-ht3ry9i0	257	34	acidifying	acidify	VBG
cord-104223-ht3ry9i0	257	35	clathrin	clathrin	NN
cord-104223-ht3ry9i0	257	36	-	-	HYPH
cord-104223-ht3ry9i0	257	37	coated	coat	VBN
cord-104223-ht3ry9i0	257	38	secretory	secretory	NN
cord-104223-ht3ry9i0	257	39	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	258	1	The	the	DT
cord-104223-ht3ry9i0	258	2	transmost	transmost	NN
cord-104223-ht3ry9i0	258	3	cisternae	cisternae	NN
cord-104223-ht3ry9i0	258	4	of	of	IN
cord-104223-ht3ry9i0	258	5	the	the	DT
cord-104223-ht3ry9i0	258	6	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	258	7	complex	complex	NN
cord-104223-ht3ry9i0	258	8	:	:	:
cord-104223-ht3ry9i0	258	9	a	a	DT
cord-104223-ht3ry9i0	258	10	compartment	compartment	NN
cord-104223-ht3ry9i0	258	11	for	for	IN
cord-104223-ht3ry9i0	258	12	sorting	sorting	NN
cord-104223-ht3ry9i0	258	13	of	of	IN
cord-104223-ht3ry9i0	258	14	secretory	secretory	NN
cord-104223-ht3ry9i0	258	15	and	and	CC
cord-104223-ht3ry9i0	258	16	plasma	plasma	NN
cord-104223-ht3ry9i0	258	17	membrane	membrane	NN
cord-104223-ht3ry9i0	258	18	proteins	protein	NNS
cord-104223-ht3ry9i0	258	19	Biosynthetic	biosynthetic	JJ
cord-104223-ht3ry9i0	258	20	protein	protein	NN
cord-104223-ht3ry9i0	258	21	transport	transport	NN
cord-104223-ht3ry9i0	258	22	and	and	CC
cord-104223-ht3ry9i0	258	23	sorting	sorting	NN
cord-104223-ht3ry9i0	258	24	by	by	IN
cord-104223-ht3ry9i0	258	25	the	the	DT
cord-104223-ht3ry9i0	258	26	endoplasmic	endoplasmic	NN
cord-104223-ht3ry9i0	258	27	reticulum	reticulum	NN
cord-104223-ht3ry9i0	258	28	and	and	CC
cord-104223-ht3ry9i0	258	29	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	258	30	Primary	Primary	NNP
cord-104223-ht3ry9i0	258	31	structure	structure	NN
cord-104223-ht3ry9i0	258	32	and	and	CC
cord-104223-ht3ry9i0	258	33	neuronal	neuronal	JJ
cord-104223-ht3ry9i0	258	34	effects	effect	NNS
cord-104223-ht3ry9i0	258	35	of	of	IN
cord-104223-ht3ry9i0	258	36	alpha	alpha	NN
cord-104223-ht3ry9i0	258	37	bag	bag	NN
cord-104223-ht3ry9i0	258	38	cell	cell	NN
cord-104223-ht3ry9i0	258	39	peptide	peptide	NN
cord-104223-ht3ry9i0	258	40	,	,	,
cord-104223-ht3ry9i0	258	41	a	a	DT
cord-104223-ht3ry9i0	258	42	second	second	JJ
cord-104223-ht3ry9i0	258	43	candidate	candidate	NN
cord-104223-ht3ry9i0	258	44	neurotransmitter	neurotransmitter	NN
cord-104223-ht3ry9i0	258	45	encoded	encode	VBN
cord-104223-ht3ry9i0	258	46	by	by	IN
cord-104223-ht3ry9i0	258	47	a	a	DT
cord-104223-ht3ry9i0	258	48	single	single	JJ
cord-104223-ht3ry9i0	258	49	gene	gene	NN
cord-104223-ht3ry9i0	258	50	in	in	IN
cord-104223-ht3ry9i0	258	51	bag	bag	NN
cord-104223-ht3ry9i0	258	52	cell	cell	NN
cord-104223-ht3ry9i0	258	53	neurons	neuron	NNS
cord-104223-ht3ry9i0	258	54	of	of	IN
cord-104223-ht3ry9i0	258	55	Aplysia	Aplysia	NNP
cord-104223-ht3ry9i0	258	56	Egg	Egg	NNP
cord-104223-ht3ry9i0	258	57	-	-	HYPH
cord-104223-ht3ry9i0	258	58	laying	lay	VBG
cord-104223-ht3ry9i0	258	59	hormone	hormone	NN
cord-104223-ht3ry9i0	258	60	:	:	:
cord-104223-ht3ry9i0	258	61	direct	direct	JJ
cord-104223-ht3ry9i0	258	62	action	action	NN
cord-104223-ht3ry9i0	258	63	on	on	IN
cord-104223-ht3ry9i0	258	64	the	the	DT
cord-104223-ht3ry9i0	258	65	ovotestis	ovotestis	NN
cord-104223-ht3ry9i0	258	66	of	of	IN
cord-104223-ht3ry9i0	258	67	Aplysia	Aplysia	NNP
cord-104223-ht3ry9i0	258	68	Autoradiography	Autoradiography	NNP
cord-104223-ht3ry9i0	258	69	High	High	NNP
cord-104223-ht3ry9i0	258	70	resolution	resolution	NN
cord-104223-ht3ry9i0	258	71	analysis	analysis	NN
cord-104223-ht3ry9i0	258	72	of	of	IN
cord-104223-ht3ry9i0	258	73	the	the	DT
cord-104223-ht3ry9i0	258	74	secretory	secretory	JJ
cord-104223-ht3ry9i0	258	75	pathway	pathway	NN
cord-104223-ht3ry9i0	258	76	in	in	IN
cord-104223-ht3ry9i0	258	77	mammotrophs	mammotrophs	NNP
cord-104223-ht3ry9i0	258	78	of	of	IN
cord-104223-ht3ry9i0	258	79	the	the	DT
cord-104223-ht3ry9i0	258	80	rat	rat	NN
cord-104223-ht3ry9i0	258	81	anterior	anterior	NNP
cord-104223-ht3ry9i0	258	82	pituitary	pituitary	NN
cord-104223-ht3ry9i0	259	1	A	a	DT
cord-104223-ht3ry9i0	259	2	single	single	JJ
cord-104223-ht3ry9i0	259	3	gene	gene	NN
cord-104223-ht3ry9i0	259	4	encodes	encode	VBZ
cord-104223-ht3ry9i0	259	5	multiple	multiple	JJ
cord-104223-ht3ry9i0	259	6	neuropeptides	neuropeptide	NNS
cord-104223-ht3ry9i0	259	7	mediating	mediate	VBG
cord-104223-ht3ry9i0	259	8	a	a	DT
cord-104223-ht3ry9i0	259	9	stereotyped	stereotyped	JJ
cord-104223-ht3ry9i0	259	10	behavior	behavior	NN
cord-104223-ht3ry9i0	259	11	Lysosome	Lysosome	NNP
cord-104223-ht3ry9i0	259	12	function	function	VBP
cord-104223-ht3ry9i0	259	13	in	in	IN
cord-104223-ht3ry9i0	259	14	the	the	DT
cord-104223-ht3ry9i0	259	15	regulation	regulation	NN
cord-104223-ht3ry9i0	259	16	of	of	IN
cord-104223-ht3ry9i0	259	17	the	the	DT
cord-104223-ht3ry9i0	259	18	secretory	secretory	JJ
cord-104223-ht3ry9i0	259	19	process	process	NN
cord-104223-ht3ry9i0	259	20	in	in	IN
cord-104223-ht3ry9i0	259	21	cells	cell	NNS
cord-104223-ht3ry9i0	259	22	of	of	IN
cord-104223-ht3ry9i0	259	23	the	the	DT
cord-104223-ht3ry9i0	259	24	anterior	anterior	JJ
cord-104223-ht3ry9i0	259	25	pituitary	pituitary	JJ
cord-104223-ht3ry9i0	259	26	gland	gland	NN
cord-104223-ht3ry9i0	259	27	A	a	DT
cord-104223-ht3ry9i0	259	28	bag	bag	NN
cord-104223-ht3ry9i0	259	29	cell	cell	NN
cord-104223-ht3ry9i0	259	30	neuron	neuron	NN
cord-104223-ht3ry9i0	259	31	-	-	HYPH
cord-104223-ht3ry9i0	259	32	specific	specific	JJ
cord-104223-ht3ry9i0	259	33	antigen	antigen	NN
cord-104223-ht3ry9i0	259	34	localizes	localize	VBZ
cord-104223-ht3ry9i0	259	35	to	to	IN
cord-104223-ht3ry9i0	259	36	a	a	DT
cord-104223-ht3ry9i0	259	37	subset	subset	NN
cord-104223-ht3ry9i0	259	38	of	of	IN
cord-104223-ht3ry9i0	259	39	dense	dense	JJ
cord-104223-ht3ry9i0	259	40	cored	cored	JJ
cord-104223-ht3ry9i0	259	41	vesicles	vesicle	NNS
cord-104223-ht3ry9i0	259	42	in	in	IN
cord-104223-ht3ry9i0	259	43	Aplysia	Aplysia	NNP
cord-104223-ht3ry9i0	259	44	californica	californica	NN
cord-104223-ht3ry9i0	259	45	Cellular	Cellular	NNP
cord-104223-ht3ry9i0	259	46	and	and	CC
cord-104223-ht3ry9i0	259	47	molecular	molecular	JJ
cord-104223-ht3ry9i0	259	48	biology	biology	NN
cord-104223-ht3ry9i0	259	49	of	of	IN
cord-104223-ht3ry9i0	259	50	neuropeptide	neuropeptide	NN
cord-104223-ht3ry9i0	259	51	processing	processing	NN
cord-104223-ht3ry9i0	259	52	and	and	CC
cord-104223-ht3ry9i0	259	53	packaging	package	VBG
cord-104223-ht3ry9i0	259	54	Perturbation	perturbation	NN
cord-104223-ht3ry9i0	259	55	of	of	IN
cord-104223-ht3ry9i0	259	56	vesicular	vesicular	JJ
cord-104223-ht3ry9i0	259	57	traffic	traffic	NN
cord-104223-ht3ry9i0	259	58	with	with	IN
cord-104223-ht3ry9i0	259	59	the	the	DT
cord-104223-ht3ry9i0	259	60	carboxylic	carboxylic	NN
cord-104223-ht3ry9i0	259	61	ionophore	ionophore	NNP
cord-104223-ht3ry9i0	259	62	monensin	monensin	NNP
cord-104223-ht3ry9i0	259	63	Clathrin	Clathrin	NNP
cord-104223-ht3ry9i0	259	64	-	-	HYPH
cord-104223-ht3ry9i0	259	65	coated	coat	VBN
cord-104223-ht3ry9i0	259	66	vesicular	vesicular	JJ
cord-104223-ht3ry9i0	259	67	transport	transport	NN
cord-104223-ht3ry9i0	259	68	of	of	IN
cord-104223-ht3ry9i0	259	69	secretory	secretory	JJ
cord-104223-ht3ry9i0	259	70	proteins	protein	NNS
cord-104223-ht3ry9i0	259	71	during	during	IN
cord-104223-ht3ry9i0	259	72	the	the	DT
cord-104223-ht3ry9i0	259	73	formation	formation	NN
cord-104223-ht3ry9i0	259	74	of	of	IN
cord-104223-ht3ry9i0	259	75	ACTH	ACTH	NNP
cord-104223-ht3ry9i0	259	76	-	-	HYPH
cord-104223-ht3ry9i0	259	77	containing	contain	VBG
cord-104223-ht3ry9i0	259	78	secretory	secretory	JJ
cord-104223-ht3ry9i0	259	79	granules	granule	NNS
cord-104223-ht3ry9i0	259	80	in	in	IN
cord-104223-ht3ry9i0	259	81	AtT20	AtT20	NNP
cord-104223-ht3ry9i0	259	82	cells	cell	NNS
cord-104223-ht3ry9i0	260	1	An	an	DT
cord-104223-ht3ry9i0	260	2	antibody	antibody	NN
cord-104223-ht3ry9i0	260	3	specific	specific	JJ
cord-104223-ht3ry9i0	260	4	for	for	IN
cord-104223-ht3ry9i0	260	5	an	an	DT
cord-104223-ht3ry9i0	260	6	endoproteolytic	endoproteolytic	JJ
cord-104223-ht3ry9i0	260	7	cleavage	cleavage	NN
cord-104223-ht3ry9i0	260	8	site	site	NN
cord-104223-ht3ry9i0	260	9	provides	provide	VBZ
cord-104223-ht3ry9i0	260	10	evidence	evidence	NN
cord-104223-ht3ry9i0	260	11	that	that	IN
cord-104223-ht3ry9i0	260	12	proopiomelanocorticotropin	proopiomelanocorticotropin	NNP
cord-104223-ht3ry9i0	260	13	is	be	VBZ
cord-104223-ht3ry9i0	260	14	packaged	package	VBN
cord-104223-ht3ry9i0	260	15	into	into	IN
cord-104223-ht3ry9i0	260	16	secretory	secretory	JJ
cord-104223-ht3ry9i0	260	17	granules	granule	NNS
cord-104223-ht3ry9i0	260	18	in	in	IN
cord-104223-ht3ry9i0	260	19	AtT-20	att-20	NN
cord-104223-ht3ry9i0	260	20	cells	cell	NNS
cord-104223-ht3ry9i0	260	21	before	before	IN
cord-104223-ht3ry9i0	260	22	its	-PRON-	PRP$
cord-104223-ht3ry9i0	260	23	cleavage	cleavage	NN
cord-104223-ht3ry9i0	260	24	Sorting	sorting	NN
cord-104223-ht3ry9i0	260	25	of	of	IN
cord-104223-ht3ry9i0	260	26	progeny	progeny	JJ
cord-104223-ht3ry9i0	260	27	coronavirus	coronavirus	NN
cord-104223-ht3ry9i0	260	28	from	from	IN
cord-104223-ht3ry9i0	260	29	condensed	condense	VBN
cord-104223-ht3ry9i0	260	30	secretory	secretory	JJ
cord-104223-ht3ry9i0	260	31	proteins	protein	NNS
cord-104223-ht3ry9i0	260	32	at	at	IN
cord-104223-ht3ry9i0	260	33	the	the	DT
cord-104223-ht3ry9i0	260	34	exit	exit	NN
cord-104223-ht3ry9i0	260	35	from	from	IN
cord-104223-ht3ry9i0	260	36	the	the	DT
cord-104223-ht3ry9i0	260	37	trans	trans	NNP
cord-104223-ht3ry9i0	260	38	-	-	NNP
cord-104223-ht3ry9i0	260	39	Golgi	Golgi	NNP
cord-104223-ht3ry9i0	260	40	network	network	NN
cord-104223-ht3ry9i0	260	41	of	of	IN
cord-104223-ht3ry9i0	260	42	AtT20	AtT20	NNP
cord-104223-ht3ry9i0	260	43	cells	cell	NNS
cord-104223-ht3ry9i0	260	44	Lysosomal	Lysosomal	NNP
cord-104223-ht3ry9i0	260	45	enzymes	enzyme	NNS
cord-104223-ht3ry9i0	260	46	and	and	CC
cord-104223-ht3ry9i0	260	47	their	-PRON-	PRP$
cord-104223-ht3ry9i0	260	48	receptors	receptor	NNS
cord-104223-ht3ry9i0	260	49	Preparation	preparation	NN
cord-104223-ht3ry9i0	260	50	of	of	IN
cord-104223-ht3ry9i0	260	51	EM	EM	NNP
cord-104223-ht3ry9i0	260	52	autoradiographs	autoradiographs	NNP
cord-104223-ht3ry9i0	260	53	Subcellular	Subcellular	NNP
cord-104223-ht3ry9i0	260	54	sites	site	NNS
cord-104223-ht3ry9i0	260	55	of	of	IN
cord-104223-ht3ry9i0	260	56	processing	processing	NN
cord-104223-ht3ry9i0	260	57	of	of	IN
cord-104223-ht3ry9i0	260	58	precursors	precursor	NNS
cord-104223-ht3ry9i0	260	59	of	of	IN
cord-104223-ht3ry9i0	260	60	neurosecretory	neurosecretory	NNP
cord-104223-ht3ry9i0	260	61	peptides	peptide	NNS
cord-104223-ht3ry9i0	260	62	in	in	IN
cord-104223-ht3ry9i0	260	63	the	the	DT
cord-104223-ht3ry9i0	260	64	bag	bag	NN
cord-104223-ht3ry9i0	260	65	cells	cell	NNS
cord-104223-ht3ry9i0	260	66	of	of	IN
cord-104223-ht3ry9i0	260	67	Aplysia	Aplysia	NNP
cord-104223-ht3ry9i0	260	68	:	:	:
cord-104223-ht3ry9i0	260	69	inferences	inference	NNS
cord-104223-ht3ry9i0	260	70	from	from	IN
cord-104223-ht3ry9i0	260	71	the	the	DT
cord-104223-ht3ry9i0	260	72	effects	effect	NNS
cord-104223-ht3ry9i0	260	73	of	of	IN
cord-104223-ht3ry9i0	260	74	monensin	monensin	NNP
cord-104223-ht3ry9i0	260	75	,	,	,
cord-104223-ht3ry9i0	260	76	FCCP	FCCP	NNP
cord-104223-ht3ry9i0	260	77	,	,	,
cord-104223-ht3ry9i0	260	78	and	and	CC
cord-104223-ht3ry9i0	260	79	chloroquine	chloroquine	NN