work_23gyf3p2ljeyxao3s5n6js6rtm ---- The Use of Legal Rhetoric in a Clinical Setting: Advocating the Advocates Philip B. Kraft. MD. JD The continuing intervention by courts and legislatures in the decisions traditionally reserved to psychiatry is generally perceived by mental health professionals as a threat to their practice. As jurists insist upon supervising therapists' decisions to medicate, I to hospitalize patients,2 and, indeed, to discharge them, 3 clinicians, as might reasonably be expected, retreat into a "siege mentality"4 as their expertise is called into question: Commentators remark that "legal developments ... presage a depressing future for psy- chiatry";5 and the law is portrayed as hindering effective patient care, rather than as protecting the rights of the neglected and underprivileged. In view of the uncomfortable liaison between law and psychiatry, it would seem odd indeed were practitioners to be assisting the efforts of those whom they see as the intruders while, at the same time, complaining of that intrusion. Yet this very phenomenon may be occurring. Ironically, clini- cians are unwittingly encouraging the expansion of legal influence by adopting legal rhetoric in the treatment setting. Legal rhetoric appears more frequently in the daily dialogue between therapists and the severely dis- turbed patient. In that dialogue, it promotes antagonism between the treatment team and the patient and among members of the team them- selves. The psychiatric community believes that the lawyers have introduced this antagonism. Yet therapists' own use of legal rhetoric in the context of psychiatric treatment may, paradoxically, lead to advocacy of the advocates and away from the invaluable task of further developing psychiatric exper- tise and defining more closely the parameters of decent care for the severely disturbed. Case Examples These case examples may prove to be illustrative. Case I N. is a 26-year-old single male patient at a state-sponsored center providing intensive day treatment for those suffering from various schizo- phrenic disorders. His treatment includes individual psychotherapy, exten- sive milieu and group activities, family treatment, and medication. After several months of treatment, it became known that N. made it his regular practice to visit several nonaffiliated emergency services in the area where Dr. Kraft·s addrl'ss is 229 /-Iarvard St.. Cambridge. MA 0213Q. Bull Am Acad Psychiatry Law, Vol. 13, No, 4, 1985 313 Kraft he would receive prescnptlOns for numerous psychotropic agents and antiparkinsonian drugs. His half-way house, moreover, reported that N. had been abusing alcohol. The center, having attained the agreement of the catchment area state hospital, drew up a plan wherein N. would be admitted to that hospital's special treatment unit for detoxification and would make a gradual transition back into full-time day treatment. N. himself acquiesced in the plan. On a Friday, one week after hospitalization, he submitted a three-day notice, announcing his intention to leave the unit. The state hospital was permitted by statute to detain him on the unit until the following Tuesday.6 Nonetheless, N. was immediately discharged. On Sun- day, he overdosed and was hospitalized on the psychiatric unit of a general hospital, returning to day treatment one week later. A "patient at risk" committee of the Community Mental Health Center investigated the inci- dent. The state hospital staff justified their decision to discharge N. when they did, on the sole ground that they were unwilling to "interfere with his civil liberties." Case 2 B., a 38-year-old woman, was also receiving intensive treatment at the day center for a schizophrenic illness. B. had been referred to the center by her psychotherapist who worked at a neighborhood clinic, affili- ated with the day center and part of the same Community Mental Health Center. B. 's therapist had expressed the wish to continue seeing B. in individual psychotherapy while other treatment modalities were provided by the day center. Thus, B. participated in the center's group program and received her medication there, while she saw her psychotherapist for 15 minutes every two weeks. Day center staff voiced concern over B.'s persis- tent withdrawal and reticence. Because B. was foreign-born, the staff con- sidered the possibility of a language barrier or culture gap. B. 's family refused to participate in the treatment program. About one year after admission, B. precipitously announced that she was going away on vacation for a week. When she failed to return on schedule, the staff phoned her family who said that B. was still away. In the meantime, B. 's psychotherapist, who had been contacted by staff about an unrelated matter, admitted knowing a "secret" which she felt she might convey to the center staff at this point, namely, that B. had not gone on vacation but had terminated treatment and taken a job at a local department store. When challenged by the day center staff, the therapist argued that she had to keep the secret for as long as she had, in order to "advocate for" B. and her family; the therapist and B. had feared that the center would try to dissuade B. from pursuing employment. Sadly, B. was unable to maintain the job. She applied for readmission to the day program two and one-half weeks after her departure. 314 Bull Am Acad Psychiatry Law, Vol. 13, No.4, 1985 Legal Rhetoric in a Clinical Setting The Failure of Clinical Understanding In both of these cases, the use of legal rhetoric signaled the failure of clinical understanding: The concepts of "liberties" and "advocacy"-once raised-seemed to assume lives of their own, dictating outcomes not in keeping with a common sense appraisal of the instant, clinical pictures. In Case 1, the state hospital staff had the legal right, pursuant to applicable statute, to keep N. on the unit for at least three days, in which time they might have thoroughly evaluated his potential for suicide. Furthermore, within the statutorily allowed period, they could have conferred with the day center stafTwho probably had a considerably broader knowledge of the patient. They might, as a matter of initial import, have utilized the time to explore with N. the reasons behind his sudden wish to leave; N. might have been persuaded to change his mind. The staff, in any case, was not confronted with a draconian choice between discharging N. on the spot and immediate resort to formal commitment procedures. 7 However, the staff, in Case 1, failed to see the extant law as supporting their right, if not their duty, to exercise a deliberate and reasoned clinical judgment. Similarly, in Case 2, routine clinical judgment would have mandated that B.'s psychotherapist not rely on her minimal contact (fifteen minutes every two weeks) with B. in order to determine the relevant interests to be "advocated." Treatment of the severely ill usually requires the participation of a mUltidisciplinary team, whose collaboration and collective judgment yield optimal results. 8 Had the therapist not been distracted by her own ideas of the law, she might have inquired into the psychodynamic constel- lation at play in B. 's "fear" that the extended treatment team would "discourage" her, a fear possibly shared by B.'s family who refused treat- ment. Collaborative discourse might have clarified the nature of B.'s reti- cence as well as that of the family's apparent resistance to treatment. Nevertheless, the therapist, I believe, wrongly concluded, albeit in good faith, that her silence was legally, if not clinically, indicated. In both of these examples, experienced clinicians were somehow misled through legalistic notions into pursuing courses of action that contravened the most basic clinical considerations. Perhaps the phrase "course of action" warrants emphasis in that, in these two cases, legalistic notions furnished the impetus for action rather than discussion. One would typically expect the veteran clinician to choose talk above action; but in these examples, the exception seems to have become the rule.9 Because of the increasing significance of the law to the practice of psychiatry, the question of how the law is being received in daily practice must be addressed. It is my hypothesis that in the daily practice of psychia- try, clinicians misperceive the law, recreate it based on their misperceptions, and conjure up "legalisms" for disturbing reasons. Bull Am Acad Psychiatry Law, Vol. 13, No.4, 1985 315 Kraft Why the Failure? The clinical decisions in these cases, I maintain, represent failures in clinical understanding concealed behind the language of the law. The clinicians described violated the most elementary among therapeutic principles: they seemingly forgot the concepts of ambivalence and acting out, inter alia, concepts most certainly inculcated in them at an early stage of their training. Rather than turning toward these concepts, they reached for the less familiar idioms of "civil liberties" and "advocacy" in entering into commonplace, clinical interactions. One possible explanation for their abandonment of the familiar for the foreign is that clinicians do not understand the law; that they are, therefore, intimidated by it and thus try to elude it by anticipating any conceivable legal difficulty which could arise, even if such anticipation entails the abandonment of zealously guarded clinical tenets. Not only may clinicians attempt to avoid the concrete possibilities of litigation but they may, on a broader scale. try to second-guess courts and regulators. In Case I, perhaps the stafT immediately discharged N. for fear that, absent a clear demonstra- tion of his suicidal potential, N. might have cause to sue the hospital if they chose to detain him. Perhaps this was an instance in which a little knowledge of the law was misleading. StafT members who have done some reading in the law might imagi!1e N. 's bringing an action on a theory of deprivation of liberty. cruel and unusual punishment, maybe even lack of procedural due process. But it is less likely that stafT, having gone this far, would know quite enough about the law to console themselves with the thought that, absent "bad faith," they are unlikely to be held liable in any event for exercising reasonable clinical judgment. lO Thus, arguably, a modicum of legal information could frighten stafT into going against their best clinical judgment. Their concern might be moderately compelling were it not for two factors which it fails to embrace. First, N., in Case I, gave no hint that his wish to leave the detoxification unit was founded on any concern for his civil liberties. He simply stated that he wished to leave; his motivation to leave was never revealed. The stafTproferred the language of "liberties"-not the patient. In short, there was no realistic basis here on which the stafT could conclude that N. was predisposed either to view his situation in terms of a loss of liberty or to seek legal assistance were his request to leave denied. Of course, the fear of litigation need not be grounded in reality. But it is highly doubtful that an experienced stafT of a state hospital would be ignorant of the extent of and limits on its power. I I N. could hardly have been the first patient to have presented this particular clinical dilemma. The stafT, on numerous occasions, had both held patients like N. (although perhaps patients more overtly at risk) beyond the statutory period as well as gone on to petition the court for com mitment. Yet, in N.'s case, they 316 Bull Am Acad Psychiatry Law, Vol. 13, No.4, 1985 Legal Rhetoric in a Clinical Setting asserted his civil liberties as standing in their way of being able to effectuate the agreed upon treatment plan. An "ignorance of the law" theory might be more applicable in Case 2. The therapist who decided to withhold a significant, clinical datum from B. 's treatment team may have been moved by considerations of patient confidentiality or B.'s right to privacy. Certainly, these are areas of the law which plead for definition, especially in the context of the public mental health system. 12 Generally, "[ilt is not considered a breach of confidentiality to disclose information to those who are assisting the primary caregiver's efforts. This includes supervisors, members of a hospital's milieu staff, and colleagues who are involved directly in the patient's treatment".1J But statutory provisions might be unclear and the concepts of privilege, confi- dentiality, and right to privacy difficult to distinguish. B.'s therapist may have preferred to err in the direction of confidentiality rather than risk a lawsuit. And also, in Case 2, the clinical picture offers a slightly more substantial basis for the therapist's fear of the possibility of litigation. Although there was no mention of litigation, the clinical picture could be read to imply that there was already disagreement between B. 's family and the day treatment center. It is possible that B. 's silence at the day center concealed a measure of hostility toward day care personnel. After all, B. and her family chose to inform only the psychotherapist of their plan for B. Taken at face value, these several observations and inferences could justify a therapist's being more than ordinarily mindful of legal guidelines. Again, however, this explanation is unsatisfactory on two grounds. First. B's psychotherapist had participated fully in at least two treatment confer- ences with the extended treatment team, in which she had reasonably shared "confidences" regarding B.'s psychotherapy. The ignorance of the law theory-to be truly satisfactory-would have to include some explanation of the therapist's sudden crisis oflegal conscience at that particular juncture in the treatment and about that particular treatment issue. Such explanation is not apparent. Second, B's therapist did not articulate concerns of "confidentiality" as responsible for her decision to keep silent. While one might. as a matter of hindsight, read such concerns into the clinical picture, the therapist spe- cifically stated that she saw her role as that of B.'s advocate. She believed that she was advocating for B. by guarding B.'s secret. The conclusion to which one is led is that fear and ignorance of the law, in themselves, cannot account for the clinicians' use of legal rhetoric in the absence of some realistic threat of litigation. In neither case example did the patient raise the specter of the law; in both examples, it was the treaters Who first introduced legal concerns as referents in the clinical dialogue. 14 Bull Am Aced Psychiatry Law, Vol. 13, No.4, 1985 317 Kraft The inescapable implication is that these clinicians, for reasons entirely of their own and for benefits which would inure only to them, donned the clothing of the legal wolf. So the inquiry devolves, in the end, to an examination of those benefits which the clinician may stand to attain through the use of legal rhetoric. In standing back from the case examples for a moment and regarding them only with a view toward the result achieved in each instance, a curious similarity between them emerges. In Case I, the clinician's use of legal rhetoric resulted in N.'s discharge from the hospital. In Case 2, the result was an interruption in B.'s treatment. In both cases legal rhetoric was used to distance the treaters from the treated. In neither case did the law actually require withdrawal of treatment. That legal rhetoric should be used to end treatment rather than promote it should hardly be surprising: "The awesomeness of [schizophrenia] causes us to distance ourselves from those who manifest it."'5 The simple fact of being a clinician does not immunize against the urge to "avoid[ ] the extreme aberrations of schizophrenic behavior. "16 The use of "Iegalisms" as a defense against "the well-known psychic strains of empathic engagement with the mentally ill" has received trenchant comment. 17 Thus, for example, the "inappropriate failure to petition" for commitment, as demonstrated in Case I, may derive not only "from wishes to be rid of the troublesome patient but may derive as well from defensive denial of the seriousness, dangerousness or lethality of the patient's clinical state."18 From a more cynical perspective, in the specific contexts of the overcrowded, under- funded state hospital and the neighborhood clinic where therapists struggle to keep up with burgeoning caseloads, legalisms may furnish no more than ready excuses for reducing patient census and, consequently, the c1inicans' workload. In other words, if there is no good clinical justification for discharging a patient, maybe a legal one will do. '9 But why a leKal excuse, rather than an ethical excuse, a philosophical excuse or a therapeutic excuse? Where is the power which, even in its absence, the law exerts on clinicians such that the talk of liberties and advocacy permeates the therapeutic dialectic? The answer is to be found not in the reality of contemporary jurisprudence, but rather in its symbolic value. For those who labor outside the legal arena proper, the law may be perceived as a source of certainty, solidity, and finality and the rhetoric of liberties and advocacy comes to represent the decisiveness of those in power. One performs certain acts and refrains from others because ··that is the law" and, despite instances in which one may entertain doubts about the law's being quite what it is. it continues to exert an almost mystical appeal as the final arbiter of human affairs. 318 Bull Am Acad Psychiatry Law, Vol. 13, No.4, 1985 Legal Rhetoric in a Clinical Setting The dissonance between legal and psychiatric modes of reasoning has been commented upon. 20 Yet the dissonance, I believe, does not necessarily imply that psychiatric practitioners are, as a result, immune to fascination with the law as the emblem of certainty. One might expect, moreover, that the symbolic influence of the law on clinicians will be strongest in those specific clinical areas wherein clinicians feel themselves least secure; that clinicians may be most prone to reaching to legal concepts as providing "the answers" in situations in which psychiatric science has foundered. It may well be, in other words, that clinicians succumb to legal influence not simply because of ambivalence,21 but because of the limitations on their own expertise. Clinicians may be trying not simply to rid themselves of troublesome patients, but to find answers in situations where they are at a loss as to what to do. And where is one most apt to encounter such situations? They are to be found in the state hospitals and community clinics, where clinicians are daily admitting chronic patients who are likely to have already exhausted the gamut of available therapies22-chronic patients for whom advances in psychopharmacology may mildly ameliorate symptoms but do not effect a cure. Clinicians are being called upon by patients, families, referring agen- cies, and the courts to "do something"-to "take care of' a burgeoning population for whose ills there are no simple solutions. Thus, the care of the chronic patient is precisely the area in which clinical certainty is lacking; for after the patient has uhdergone trials of antipsychotic medications, antidepressants, antianxiety agents, lithium carbonate, behavioral therapies, vocational counseling, and the like, the question of what to do next insistently presses for an answer.23 In Case I, the state hospital staff likely knew very well how to talk with N. to persuade him to withdraw his three- day notice. B.'s psychotherapist, in Case 2. likely knew as well how to draw on the support of the treatment team to convince B. to continue her program. But by choosing not to use routine, therapeutic skills to maintain the therapeutic relationship, these clinicians managed to escape their own sense of hopelessness about the future of two severely disturbed patients. At the heart of the treatment of the chronic psychosis lies a void that has yet to be filled with concrete guidelines for a demonstrably meaningful dialogue between patient and therapist. 24 To fill that void, then, the therapist borrows from that perceived source of certainty, the law. The language of liberties and advocacy, with its aura of finality, is used to answer the unanswerable. Notwithstanding the inap- propriateness of such language to the clinical occasion, the clinician, in a search for definition. stretches the meaning of the law in applying it to the situation before him in order to. at least. do something. This distortion of Bull Am Acad Psychiatry Law, Vol. 13, No.4, 1985 319 Kraft the law, in tum, makes the clinician appear naive in the eyes of the lawyers. Furthermore, the clinician fails to recognize those instances in which the law in actuality protects his decision-making power. 25 Appreciating this argument in its most exaggerated form may serve to highlight the dangers inherent in imitating the lawyers. The dangers which clinicians face in so doing are three: the danger of relying on the law to furnish solutions to clinical problems (borrowing the "'emperor's clothes"); the danger of importing an adversariallanguage into the therapeutic sphere; and the danger of furthering the intrusion of the law into territory where it does not belong and where its presence is lamented. The Emperor's Clothes To the outsider, the law may represent all that is certain, but those inside the law are all too familiar with the insecurity of the law. The legal realist movemene6 and its successor, the critical legal studies movement, have come to recognize the essential indeterminacy of every legal debate. 27 The grand scheme of 19th century law has failed; legal categorization has collapsed 28 and contemporary scholars acknowledge that the law is molded to reflect the wishes of the powerful and to reproduce extant hierarchies. 29 Thus, not only are legal principles fluid but they also serve as a method of manipulation. Radical commentators portray the "'science of law," propounded by Christopher Columbus Langdell, as a tool with which classism, racism, and sexism have been perpetuated, while deceiving those oppressed into believing that justice is being served. 30 Even the most moderate among jurists have noted the void at the heart of the law. where conflict remains as conflict and where overarching principles are unavailable to provide the much desired sense of finality and repose. 31 Thus, those who seek answers in the provinces of the law for the problems of the chronic patient are bound to be disappointed. The task of developing a meaningful dialogue with patients who have been left behind by clinical science cannot be passed on to lawyers, themselves coping with the vague- ness at the heart of the law. Legal certainty is a facade, and, moreover, lawyers whose practice bears on mental health must deal with the twin uncertainties of law and psychiatry. They confront the same concerns as clinicians face in their work with the severely disturbed: how to define irrationality and how, once the boundary is delineated, to bridge the gap between madness and sanity. Importing the Adversarial Stance into the Clinical Arena Not only are the answers to these problems not to be found in the law, but the very use of legal rhetoric in an attempt to find those answers introduces a noxious, foreign element into clinical dialogue. Notions of advocacy with their implications of a "zero-sum game"3~ are at odds with the basic premises of the therapeutic encounter. For the clinician to call herself an advocate, in the legal sense. of her patient is to place herself in a position of antagonism 320 Bull Am Acad Psychiatry Law, Vol. 13, No.4, 1985 J Legal Rhetoric in a Clinical Setting vis-a-vis her fellow clinicians. In a clinical situation which demands a collaborative effort-again, most typically, in the case of the severely disturbed-the use of such language is susceptible to being interpreted as an insinuation that the "clinician/advocate" is the only individual on the team who is taking it upon herself to support the patient's best interests, in the face of opposition from other team members. It would hardly be surprising, therefore, were legal rhetoric, however innocently used, to in- crease friction among those who should be working together in the interest of the patient. Similarly, the invocation of the language of liberties implies a struggle between therapist and patient. It is not a foregone conclusion, e.g., that a patient like N. who submits a three-day notice really means to gain his release from the hospital. 33 The act of submitting the notice may be an invitation to the staff to enter into a dialogue with the patient about the significance of the hospitalization, its goals, and anticipated duration or it may be merely an attempt by the patient to express some disappointment in the direction that his hospital stay has taken up to that point. When the treatment team responds with talk of civil liberties, staff members are declining the invitation to enter into a dialogue of clarification. Instead, they are squaring up to the patient, countering his inarticulate invitation to engage in a dialogue with their own offer to engage in confrontation. The original meaning of the three-day notice is lost in the ensuing exchange. In this way, legalisms take the place of therapeutic colloquy and clinicians lose an opportunity to enlarge upon our understanding of psychotic phenomena. Welcoming the Invader The incorporation of legal rhetoric-however it may be altered from its original, contextual meaning-into the clinical setting seems to signal psychiatry's acknowledgment of defeat. Psychiatry is giving in to the perceived aggressor and adopting its language in the process. 34 The true danger lies not so much in psychiatry's cloaking itself in the language of the law as it does in the fact that this exercise diverts energy away from the far more important task of developing a language from within the psychiatric community-a language with which to contend with the needs of the chronic patient population. Absent such a language, the psychiatric community may be preserving a vacuum which the law will seek to fill.35 Psychiatry's mimicry of the law is a temporizing measure. It forestalls the inevitable encounter with the problem of the unremittingly psychotic patient. The act of mimicry will bring no rewards. Unsolved problems of the chronic patient cannot be solved, but only masked, by borrowed legal rhetoric. I suggest that, in lieu of borrowing from the troubled purview of the law, helping professionals once again undertake the painful work of introspection. Provocative suggestions for new visions have been made. 36 Bull Am Acad Psychiatry Law, Vol. 13, No.4, 1985 321 Kraft Alternative approaches to the psychotherapy of psychosis merit considera- tion after years of neglect. 37 Until a new and relevant language is forthcom- ing, those who purport to advocate for the patient may, in fact, be advocating the advocates. References I. ROK£'rs 1'. Commissioner o/Ih£' D£'parlmenl 0/ M£'nlal lIeallh, 390 Mass. 489, 458 N.E.2d 308 ( 1983) 2. O'Collnor 1'. DOllaldson. 422 U.S. 563 (1975) 3. DurjlinK£'f 1'. Arliles. 234 Kan. 484. 673 P.2d 86 (1983) 4. Talbott JA: "i£'llpoinl: whal on £'arlh can h£' don£' 10 save us/rom all Ihis Irouhl£'? Psychiatr News. Sept. ::!I. 1984. at 2. Col. I 5. Id 6. See Mass. Ann. Laws ch. 123. § II (Michie/Law Co-op. 1981) 7. The statutory scheme takes into account precisely the situation wherein a psychiatric staff is not fully comfortable with the premature discharge of a voluntarily admitted patient whose safety is in question. Mass. Ann. Laws ch. 123. § II (Michie/Law Co-op. 1981) provides. in relevant part: "Where persons or their parents or guardians are required to give three days notice of intention to leave or withdraw. an examination of such persons may be conducted to determine their clinical progress. their suitability for discharge and to investigate other aspects of their case .... Such person may be retained at the facility beyond the expiration of the three-day notice period if, prior to the expiration of the said three-day notice period. the superintendent files with the district court a petition for the commitment of such person at the said facility. ~ 8. Bachrach LL: Asylum and chronically ill psychiatric pati£'nls. Am J Psychiatry 141 :975, 1984 9. "Action as Defense. In common with other aspects of care. the procedures of the law provide the trainee with opportunity to discharge anxiety through such activity as consulting lawyers. forensic psychiatrists. court clerks. legal officers. and so on. Such consultations may, of course, represent valid and necessary researches as well as symptomatic acts." Gutheil, Legal defense as ego defense: alpecialji)rm olr£'sistance to Ihe therapeutic process. Psychiatr Q 51 :251,255, 1979. Dr. Gutheil's penetrating observations of the "excesses of legalistic zeal" in psychiatric trainees are further commented on in this paper. See infra text accompanying notes 17-19 10. ROKas \'. Okin, 478 F. Supp. 134::!, 1380-1383 (D. Mass. 1979) II. Gutheil TG. Magraw R: Ambivalence, alliance. and advocacy: misunderstood dualities in psychiatry and law. Bull Am Acad Psychiatry Law 12:51, 55,1984 I::!. Miller RD: Confidentiality or communication in the treatment of the mentally ill. Bull Am Acad Psychiatry Law 9:54. 1981 13. Gutheil T. Appelbaum P: Clinical Handbook of Psychiatry and the Law 9, 1982. See also Slovenko R: Psychiatry and Law 437. 1973. ("[IJt is only the promiscuous nontestimonial disclosure of information which leads to liability.") 14. These examples are to be distinguished from the case where the patient's lawyer is actually present on the ward. engaged in a confrontation with an ambivalent clinician. Sec Gutheil and Magraw, supra note 11, at 56. In the latter case, it is easy to see how the clinician could feel overwhelmed by the attorney. But in the case examples discussed in this paper, the struggle appears to lie totally within the mind of the treating clinician. 15. Day M. Semrad EV: Schizophrenic reactions, in Harvard Guide to Modern Psychiatry. Edited by Nicholi A Jr. Cambridge, MA. Harvard University Press, 1978, p. 199 16. Id See also Minow and Kraft. Deinstitutionalization: professional prescriptions and ideologies, paper presented at the conference on Chronic Mental Patients in the Community, Harvard University Division on Health Policy. Stanford University Department of Psychiatry, December 3. 198::! (unpublished manuscript) (lawyers and psychiatrists alike develop forms of rhetoric which, in order to avoid "professional pain." serve to distance the professional from the patient) 17. Gutheil TG. supra note 9, at 252 18. Id at 253 19. Gutheil also remarks that "[iJn certain situations relating to gathering important data about a new patient (from other agencies or institutions, relatives, outside physicians and so on), the issue of confidentiality may be inappropriately invoked quite simply to avoid doing this work which, though necessary. is otten tedious and time-consuming." Id at 252 20. Gutheil TG. Magraw R . . II/pra note II. Sec also Gutheil and Mills: Legal conceptualizations, legal fictions. and the manipulation of reality: contlict between models of decision making in psychiatry and law. Bull Am Acad Psychiatry Law 10: 17. 1982 (law and psychiatry operate through differing models of reasoning) ::! I. Gutheil TG. Magraw R. Hlpra note II. at 56 322 Bull Am Acad Psychiatry Law, Vol. 13, No.4, 1985 Legal Rhetoric in a Clinical Setting 22. Bachrach LL: Young adult chronic patients: an analytical review of the literature. Hosp Community Psychiatry 33: 189. 1982 23. "[I]t is clear that the biological and behavoria1 approaches to psychiatry. though promising. have not yet solved all the problems of either serious mental disorders or less severe disturbances." Stone. The new paradox of psychiatric malpractice. New Eng! J Med 311: 1384. 1385. 1984 24. Bellak The schizophrenic syndrome: what the clinician can do until the scientist comes. in Disorders of the Schizophrenic Syndrome. New York. Basic Books. 1979, p. 585 25. Sec supra note 7 26. Mensch E: The history of mainstream legal thought, in The Politics of Law. Edited by Kairys D. New York, Pantheon 1982. pp. 26-29 27. See generally Dalton. Book Review. Harv. Women's L.J. 6:229 (1983) (reviewing the Politics of Law (D. Kairys. ed .. 1(82)) 28. Gilmore. G: The Death of Contract. Columbus. OH. Ohio State University Press. 1974 29. Rabinowitz Y: The radical tradition in the law, in The Politics of Law. Edited by Kairys D. New York. Pantheon 1982, p. 310 30. "In a broader sense. the ideological role of concepts like legal reasoning is but one aspect of a larger social phenomenon. In many areas of our lives, essentially social and political judgments gain legitimacy from notions of expertise and analysis that falsely purport to be objective, neutral. and quasi-scientific .... If religion is the opiate of the masses, it seems that objectivity, expertise. and science have become the tranquilizers." Kairys, Legal Reasoning, in The Politics of Law 11, 17 (D. Kairys ed. 1982). 31. "The true grounds of decision are considerations of policy and of social advantage, and it is vain to suppose that solutions can be attained merely by logic and the general propositions of law which nobody disputes. Propositions as to public policy rarely are unanimously accepted, and still more rarely, if ever. are capable of unanswered proof." ,'egeialm v. GUn/ncr, 167 Mass. 92. 106,44 N.E. 1077, 1080. 1896 (Holmes J. dissenting) 32. Gutheil TG, Magraw R, supra note 1 \, at 57 33. Id at 52-53 34. Ironically, at the same time, the law seems to be embroiled in a struggle to limit psychiatric intrusions by reforming the insanity defense, for instance. See Insanity Defense Overhaul Moves Ahead. American Bar Association Journal. Feb. 1984, at 25 35. Kraft P: The right to refuse psychiatric treatment: professional self esteem and hopelessness, in Psychology, Psychiatry and Criminal Law: A Clinical and Forensic Handbook. Edited by Ewing C. In press 36. Unger RM: A program for late twentieth-century psychiatry. Am J Psychiatry 139: 155, 1982 37. Federn P: Ego Psychology and the Psychoses. London, H. Karnak, 1977 Bull Am Aced Psychiatry Law, Vol. 13, No.4, 1985 323 work_24bd7qepuffibnb25gwqr2yloq ---- wp-p1m-38.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-38.ebi.ac.uk no 218194226 Params is empty 218194226 exception Params is empty 2021/04/06-02:09:19 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. Message ID: 218194226 (wp-p1m-38.ebi.ac.uk) Time: 2021/04/06 02:09:19 If you need further help, please send an email to PMC. Include the information from the box above in your message. 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Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_2ayfulzxajd2hhuxxr24tw2ip4 ---- Methods for smoking cessation and treatment of nicotine dependence 820 BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY 71 (6) PART 1 NOVEMBER/DECEMBER 2005 http://www.rborl.org.br / e-mail: revista@aborlccf.org.br Methods for smoking cessation and treatment of nicotine dependence Summary Aracy Pereira Silveira Balbani1, Jair Cortez Montovani2 1 Ph.D. in Medicine, Volunteer Professor, Discipline of Otorhinolaryngology and Head and Neck Surgery, Medical School, Botucatu, Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP). 2 Full Professor, Discipline of Otorhinolaryngology and Head and Neck Surgery, Medical School, Botucatu, Universidade Estadual Paulista “Júlio de Mesquita Filho” (UNESP). Address correspondence to: Aracy P. S. Balbani - Rua Capitão Lisboa 715 cj. 33 18270-070 Tatuí SP. E-mail: a_balbani@hotmail.com This article was submitted through SGP on May 11, 2005 and approved on June 20, 2005. Smoking is related to 30% of cancer deaths. It is a risk factor for respiratory tract, esophagus, stomach, pancreas, uterine cervix, kidney and bladder carcinomas. Nicotine induces tolerance and addiction by acting on the central dopaminergic pathways, thus leading to pleasure and reward sensations within the limbic system. It stimulates the central nervous system (CNS), enhances alertness and reduces the appetite. A 50% reduction of nicotine consumption may trigger withdrawal symptoms in addicted individuals: anxiety, anger, sleep disorders, hunger, cognitive dysfunction and cigarette craving. Medical advice is the cornerstone of smoking cessation. Pharmacotherapy of nicotine addiction comprises first-line (bupropion and nicotine replacement therapy) and second-line (clonidine and nortriptyline) drugs. Bupropion is a non-tricyclic antidepressant that inhibits dopamine uptake, whose contraindications are: epilepsy, eating disorders, uncontrolled hypertension, recent alcohol abstinence and current therapy with MAO inhibitors. Nicotine replacement therapy can be done with patches or gums. Counseling groups and behavioral interventions are efficacious. The effects of acupuncture on smoking cessation are not fully elucidated. Prompt smoking cessation or gradual reduction strategies have similar success rates. Key words: smoking, nicotine, tobacco use disorder, tobacco use cessation, bupropion. REVIEW ARTICLE Rev Bras Otorrinolaringol. V.71, n.6, 820-6, nov./dec. 2005 821 BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY 71 (6) PART 1 NOVEMBER/DECEMBER 2005 http://www.rborl.org.br / e-mail: revista@aborlccf.org.br INTRODUCTION Tobacco is produced by two plant species - Nico- tiana tabacum and Nicotiana rustica, which come from the Peruvian and equatorial Andes. These plants were found out approximately 18,000 years ago, when Asiatic populations migrated to America1. When Christopher Columbus arrived in the New World, the cultivation and use of tobacco had already been disseminated among Indians over the continent. It had several applications, including religious rituals and as insecticide in agriculture. Tobacco was smoked in pipes, inhaled, chewed, eaten, and drunk as tea. Important medicinal plant, it was used for intestinal wash-ups, skin smear to kill louses, instilled as eye-wash and used in ointments, analgesic and antiseptic formulations1. Aware of smoking habits and the tobacco medicinal properties, explorers decided to take the plant seeds to Europe. In Portugal and in Spain, tobacco was cultivated in royal palace gardens, while nobles used it to fight can- cer. Rapidly, tobacco became much valuable in Europe, while English pirates invaded and plundered Spanish ships coming from America, till the British government decided to cultivate the plant in several colonies1. In 1850, the first manufactured cigarettes were sold in England, whose consumption became popular during the First World War. Smoking habits summit took place in the 50 and 60’s, declining in certain countries from 1970 and on1. Today, there are more than a billion tobacco us- ers around the world, among which 90% started smoking in the adolescence2. From 1920’s, the increase of lung cancer incidence was observed, which was confirmed in several studies thirty years later. In 1971, a formal report was published in the United States confirming that “smoking negatively affects human health and contributes for the onset of severe diseases”1. Currently, the World Health Organization accounts for more than four millions fatal victims caused by ciga- rette each year2. It is known that smoking is related to at least 30% of cancer deaths. It is a risk factor for the onset of lung, mouth, pharynx, larynx, esophagus, stomach, pancreas, uterine cervix, kidney and bladder carcinomas3. Moreover, morbidity by cardiovascular and cerebrovascular diseases, chronic obstructive pulmonary diseases (COPD) and peptic diseases, as well as other affections, is higher among smokers1. In 1988, a new North-American report concluded that nicotine found in cigarettes and in other tobacco products is a drug that causes dependence. It is estimated that 24% of the adult population in several countries, Brazil included, are nicotine dependent4. Frequently, otorhinolaryngologists receive smokers with inflammatory or tumoral diseases of the upper air- ways. It is fundamental to diagnose and treat the chemical dependence in these patients, promoting smoking cessa- tion in order to prevent or cure these affections. The authors present a pharmacology outlook, ad- dressing actions and nicotine dependence, as well as treatment modalities available for smoking cessation which may be prescribed by otorhinolaryngologists. Literature Review Indexed studies were reviewed through Lilacs and Medline databases under the keywords in Portuguese, such as “tabagismo”, “nicotina”, “transtorno por uso do tabaco”, “abandono do uso do tabaco”, “bupropiona” or its related links in English: “smoking”, “nicotine”, “tobacco use disorder”, “tobacco use cessation”, “bupropion”. Nicotine Pharmacology Cigarette smoke consists of volatile chemical sub- stances (92%) and particulate material (8%) resultant of tobacco combustion5. Nicotine, a tertiary volatile amine, is the most important active tobacco component4,6. When tobacco coal’s temperature reaches 800°C, racemic shapes of nicotine emerge, which form four nitrosamines with cancer potential7. However, nearly 35% of nicotine is de- stroyed during cigarette combustion; more than 35% is lost in non-inhaled smoke and 8% is not smoked6. Therefore, each cigarette contains 7-9 mg of nicotine, of which a little more than 1 mg is absorbed by the smoker4. Cured tobacco’s nicotine for pipes and cigars is alkaline and it is more easily absorbed through the mouth. On the other hand, cigarette’s nicotine is acid, therefore it is practically not absorbed by the mouth mucosa, and has to be inhaled to be absorbed by the lungs1,7. Nicotine is rapidly absorbed by the lung alveolus and reaches the brain within 10 seconds. Its half-life is of approximately 2 hours, and metabolization is mostly hepatic, through P450 cytochrome. The main enzyme in- volved is CYP2A6. Molecular biology studies demonstrate that capacity in metabolizing nicotine varies according to each individual7. CYP2A6*2 and CYP2A6*3-allele in- dividuals are less prone to be smokers, and if they do, they tend to consume less tobacco than CYP2A6*1-allele individuals8. Vasconcelos et al. (2005)9 analyzed the genetic profile of CYP2A6 in a sample of an adult Brazilian population, composed by 147 Caucasian individuals, 142 Mulattos and 123 Blacks, among which 205 were smokers or ex-smokers, and 207 were non-smokers. The alleles mostly found in this sample were: CYP2A6*1B (29.9%), CYP2A6*2 (1.7%), CYP2A6*4 (0.5%) and CYP2A6*9 (5.7%). Contrary to expectations, frequency of CYP2A6*1B-allel individuals among non-smokers was higher. Distribution of CYP2A6*1B alleles also presented racial differences, with decreasing frequency among Caucasians, Mulattos 822 BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY 71 (6) PART 1 NOVEMBER/DECEMBER 2005 http://www.rborl.org.br / e-mail: revista@aborlccf.org.br and Blacks. Presence of this allele was associated with a higher probability of nicotine dependency among Cauca- sians (a 14-fold higher risk) and Mulatto (a 3-fold higher risk), but not among Blacks. The most important nicotine metabolite is cotinine, which can be detected in urine, saliva and blood7. Only 5% of nicotine is excreted without alterations by the kidneys4. Nicotine actions The systemic actions of nicotine are mediated by nicotinic receptors found in the central nervous system (CNS), peripheral autonomic nodes, supra-renal glands, sensitive nerves and the skeletal striated muscle4. Nicotine’s main acute effects over the cardiovascular system are10: peripheral vasoconstriction, increase of the blood pressure and heart rate. Nicotine also interferes in the endocrine system, yielding the release of antidiuretic hormone and water retention. In the gastrointestinal sys- tem, nicotine acts parasympathetically, stimulating tonus increase and intestinal motor activity10. In nervous endings, nicotine stimulates release of the following neurotransmitters: acetylcholine, dopamine (DA), glutamate, serotonin and gamma aminobutyric acid (GABA)11. Nicotine is CNS stimulant, leading to increased alert- ness and to reduced appetite. After a draft, the sensation may be compared to that described by amphetamine, heroine, cocaine and crack users4. The main sensations may include dizziness, nauseas and vomiting10. Rose et al. (2003)11 studied nicotine’s acute effects over the brain blood flow in adults through tomography by positrons emission (PET). Nicotine interferes in the re- ticular formation blood flow, including areas of the pons, mesencephalus and thalamus, and plays a role in aware- ness and awakening mechanisms. Low doses of nicotine have a central stimulating effect, while higher doses have a depressing effect. Nicotine also leads to dose-dependent increase of blood flow in the left hemisphere amygdala, which may explain the anxiolytic effect of smoking. Experimental studies show that nicotine acts as en- zymatic inductor in the liver. This way it reduces half-life of several medicines such as: local anesthetics, morphine, codeine, teophyline, heparin, warfarin, amitriptyline, imipramine, propranolol, chlorpromazine, diazepam, chlordiazepoxide and indometacin. Thus, smokers may require larger doses of these medicines to have the ex- pected therapeutic effects10. Ingestion of nicotine-based insecticides may cause acute intoxication, with the following symptoms: salivation, vomiting, muscle weakness, prostration, cold sudoresis, mental confusion and hypotension. In severe cases (inges- tion of over 60 mg of nicotine), chronic convulsions and respiratory failure may occur10. Nicotine Chemical Dependency Nicotine induces tolerance (need of progressively higher doses to obtain the same effect) and dependence (desire of consumption) as it acts in the dopaminergic pathways of the mesolimbic system, reducing the tha- lamus activity4. Similarly to other psychoactive drugs, it releases dopamine in the nucleus accumbens, located in the mesencephalus, stimulating a pleasant and “rewarding” sensation8,12. After the discomfort caused by the first drafts of tobacco (sickness, dizziness, nausea), the smoker expe- rience a pleasant sensation with the use of nicotine7. According to Marques et al. (2001)4, a 50% decrease in nicotine consumption is enough to trigger withdrawal symptoms in dependent individuals. Nicotine abstinence syndrome is mediated by noradrenalin and starts 8 hours after the last cigarette, reaching a peak on the third day. Main symptoms include: anxiety, irritability, sleep disorders (insomnia and daytime sleepiness), appetite increase, cog- nitive disorders (decrease of concentration and attention) and craving. That is why nicotine-dependent individuals present abstinence relief when they smoke their first morning cigarette. Irritability during nicotine withdrawal is a common smokers’ complaint4. Our experience includes a 34-year- old patient that used to smoke about 12 cigarettes per day and had quit smoking for two months. The patient says she had physically improved during withdrawal, but started smoking again due to her husband’s insistence: “He could no longer stand my bad mood”. Unwanted weight gain is one of the symptoms that mostly upset patients under nicotine abstinence. Mostly, weight gain gets around 4 to 6 Kg13, and in some people it may reach 10% of body weight4. Women and smokers that smoke over 25 cigarettes per day tend to gain weight after smoking cessation, prob- ably due to food ingestion and metabolic adjustments4. Epidemiologic studies show that more than 70% of smokers want to quit smoking8. However, less than 10% reach their goal by their own, as discomfort caused by nicotine abstinence and craving leads most ex-smokers to relapse8,13. Relapses usually occur between two days and three months of withdrawal13. Cox et al. (2003)3 alert that 58% of cancer patients continue smoking after diagnosis, usually due to behavioral habit, anxiety or stress. Treatment of Nicotine Dependency Medical support may enhance the success rate in smoking cessation13. Patient and Family Counseling Talking with the patient is the first step for smok- ing cessation. It is important to evaluate if the patient is 823 BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY 71 (6) PART 1 NOVEMBER/DECEMBER 2005 http://www.rborl.org.br / e-mail: revista@aborlccf.org.br nicotine-dependent or not, the quantity smoked, desire to quit, presence of associated diseases and feasible treat- ment modalities4,6. There are many ways to assess nicotine depend- ency: through the International Classification of Diseases (ICD-10), Diagnosis and Statistics Manual of the Ameri- can Psychiatric Association (DSM-IV), and others4. The Fagerström Scale for nicotine tolerance and dependency assessment (Table 1) has English and Swedish originals and has been adapted to several languages. It includes six questions. Total score ranges from zero to 11, where low nicotine dependency (mild) is detected when total is below three. A score higher or equal to seven indicates high nicotine dependency (severe)6. Patient should be encouraged to quit smoking at each medical consultation. Other smokers in the family must also be counseled not to smoke3. According to Jain (2003)13, gradual reduction or quit attempts to smoking cessation show the same probability of success. Pharmacotherapy Pharmacotherapy is indicated for nicotine depend- ents and is divided into: first-line therapy (bupropion and nicotine-replacement therapy) and second-line therapy (clonidine and nortriptyline). First-line Therapy Bupropion Bupropion is a non-tricyclic antidepressive that inhibits pre-synaptic dopaminergic and noradrenalin mechanisms8,14,15. Its action in the central dopaminergic pathways is believed to be the same mechanism respon- sible for craving reduction in patients under nicotine abstinency14. In the United States, bupropion is indicated for addicts smoking 15 or more cigarettes/day or presenting depressive symptoms4. Bupropion therapy should start 7 to 10 days before patient stops smoking, since this interval is necessary for the balance of pharmacotherapeutic levels2,8. The rec- ommended dosage is 150mg/day up to the third day of treatment, increasing to 300mg/day at the fourth day, and maintaining this dosage from 7 up to 12 weeks4. Clinical studies with bupropion have satisfactory results, presenting twice the period of abstinence when compared with placebo, plus reduced weight gain4. Bupropion’s adverse effects occur in 6-8% of patients16. The most common symptoms are: insomnia, restlessness and xerostomia 8. Kolber et al. (2003)16 empha- size that incidence of adverse effects was observed in clini- cal studies sponsored by a pharmaceutical manufacturer, in which 35% of patients had not completed treatment. Table 1. Portuguese version of Fagerström scale for nicotine-dependence evaluation (adapted by Do Carmo; Pueyo, 2002). Questão Resposta Pontuação 1. Quanto tempo você demora para fumar o primeiro cigarro da manhã? menos de 5 minutos 3 6-30 minutos 2 31-60 minutos 1 mais de 60 minutos 0 2. É difícil abster-se e não fumar nos lugares onde é proibido sim 1 (p. ex., hospital, biblioteca, igreja, ônibus, etc.)? não 0 3. Se tivesse de escolher, que cigarro lhe custaria mais deixar de fumar? o primeiro da manhã 1 todos os demais 0 4. Quantos cigarros você fuma por dia? 10 ou menos 0 11-20 1 21-30 2 31 ou mais 3 5. Habitualmente você fuma mais nas primeiras horas do dia do que sim 1 no restante do dia? não 0 6. Você fuma estando doente na cama? sim 1 não 0 NOTE: score from zero to three: low nicotine-dependency (mild); score higher or equal to seven indicates high nicotine-dependency (severe). 824 BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY 71 (6) PART 1 NOVEMBER/DECEMBER 2005 http://www.rborl.org.br / e-mail: revista@aborlccf.org.br The authors carried out an independent study to evaluate 39 patients, out of which 15 (38%) discontinued the use of bupropion due to adverse neuropsychiatric effects (trembling, restlessness, and confusion), insomnia and skin eruptions. Seven patients (18%) had to reduce bupropion dosage to 150 mg/day, so side effects could be tolerated. Risk of convulsions in bupropion users is 1:1.000. For this reason, this drug is contraindicated for epileptics4. Other contraindications include: nutrient disorders (nerv- ous anorexia or bulimia), uncontrolled arterial hyperten- sion, recent alcohol abstinence and use of monoaminoxi- dase inhibitors (tranylcypromine or selegiline)2,4,8. Bupropion is a B-category drug according to Food and Drug Administration, which means that there are not sufficient studies on secure use of this medicine during pregnancy4. Nicotine Replacement Therapy (NRT) Combined use of NRT and bupropion almost dou- bles the success rate of smoking cessation14. In Brazil, nicotine patches and chewing gum are available in the market. In the United States, there is also the nasal spray and nicotine mouthwash14. Patches may be found in the Brazilian market in dosages of 7, 14 and 21mg/unit and each pack contains seven units. They maintain blood levels of nicotine for 16 to 24 hours17, therefore they should be replaced on a daily basis. Their effects are observed in two to three days of use18. Mean period for treatment is eight weeks4. Chewing gums contain 2mg of nicotine/unit and are sold in packages of 12 units. The following dosage is recommended18,19: a) For patients who smoke ≤25 cigarettes per day: 1 gum (2mg) at 1-2 hour intervals in the first 4 weeks up to maximum of 20 gums per day18 1 gum (2mg) at 2-4 hour intervals from the 5th to 8th week 1 gum (2mg) at 4-8 hour intervals from the 9th to 12th week b) For patients who smoke >25 cigarettes per day: 2 gums (4mg) at 1-2 hour intervals in the first 4 weeks up to maximum of 20 gums per day18 1 gum (2mg) at 2-4 hour intervals from the 5th to 8th week 1 gum (2mg) at 4-8 hour intervals from the 9th to 12th week Gums should be strongly chewed until numbness of the mouth mucosa occurs or a tobacco taste is perceived. Then the patient should stop chewing and maintain the gum between the cheeks and gingival region until numb- ness disappears, and restart chewing for 30 minutes to throw out the gum. Patient should not ingest any type of liquid while chewing the gum19. The patient must stop smoking as soon as he starts NRT. The most common systemic effects in nicotine replacement are: nausea, hiccups and headache18,20. Main adverse effect of nicotine gums is rash of mouth mucosa4. NRT is contraindicated for individuals younger than 18 years and those with severe cardiovascular dis- eases (acute myocardial infarction occurred within the previous two weeks and instable angina)4. Use of NRT is possible in nicotine-dependent pregnant women and during breastfeeding, should treatment risks and benefits be appraised2. Second-Line Therapy Clonidine may be used at a 0.1 to 0.75 mg dosage per day to relieve nicotine-abstinence syndrome’s symp- toms. Its main adverse effects are sedation and orthostatic hypotension. Sudden discontinuation of clonidine may produce hypertensive crisis4. Nortriptyline inhibits noradrenalin and dopamine mechanisms in the CNS, producing antidepressive and anxiolytic effects. At short-term, its efficacy in smoking cessation seems to be similar to that of bupropion4. Other therapies Acupuncture The Acupuncture Consensus Panel of the United States National Institutes of Health (NIH) (1998)21 confirms that acupuncture “may be useful as a supportive treatment, or acceptable alternative, or part of a comprehensive program” in drug-addiction therapy, including nicotine dependency. According to Approach Consensus and Treat- ment of Smokers of the Health Ministry (2001)19, “so far, there are not sufficient scientific evidences to corroborate the efficacy of acupuncture and of other methods, such as aromatherapy and hypnosis. Thus, acupuncture “is not recommended as a method of choice for smoking cessa- tion”, although it may be used “if this is the patient’s option and if there are no usage contraindications”. He et al. (2001)22 followed 46 adults who smoked 10 or more cigarettes per day and divided them into two groups. The study group was submitted to electroacu- puncture, auriculoacupuncture and auriculoacupressure (manual technique, without needles) for three weeks. The activated spots corresponded to the lungs, airways and mouth. Individuals of the control group were submitted to acupuncture with stimulation of spots related to the muscle-skeletal system, presumably without influence in the organs affected by tobacco. Among the study group 825 BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY 71 (6) PART 1 NOVEMBER/DECEMBER 2005 http://www.rborl.org.br / e-mail: revista@aborlccf.org.br patients, 32% abandoned smoking, against 23% of the control group. The desire to smoke was reduced in both groups, although tobacco taste significantly worsened among those submitted to acupuncture. According to the authors, acupuncture action mechanisms in smoking treat- ment remain unknown, although it is possible that tobacco taste is reduced by this technique, with consequent fall of smoking desire. So far, there are not sufficient evidences that acu- puncture is effective in treating nicotine dependency13,23, even though several patients feel better during smoking abstinence13. Cognitive-behavioral Therapy and Self-support groups Marques (2001)4 emphasizes that self-support groups and psychotherapy – individual or group – with counseling sessions are effective adjuvant factors in treat- ing nicotine dependency. This is especially significant when dependency is followed by other affections, such as depression and anxiety. Counseling helps to identify situations in which the tobacco-addicted chases a cigarette due to behavioral (after the meals, a cup of coffee, when meeting friends) or emotional reasons (anxiety, upsetting). Based on that, the tobacco-addicted learns several strategies to break the link between these factors and the act of automatic smoking14. Behavioral intervention and counseling is the base of treatment against tobacco-use among teenagers2. The National Cancer Institute (INCA) has a toll-free phone number 0800-703-7033, where information on smoking cessation methods is provided. In the call center menu options, INCA informs the phone numbers of state coordination centers for smoking treatment under the Central Healthcare System (SUS). Smokers that participate in smoking cessation groups have the right to receive pharmacotherapy without charge. Assessment of Response to Treatment Routinely, the main information for the physician to evaluate smoking reduction or cessation is self-reported smoking cessation. However, in clinical studies, it is fun- damental to adopt an objective and secure measurement to make sure that the patient has really quit smoking. The most effective method in clinical research studies for smoking cessation is blood, saliva or urine cotinine tests22. Another methodology is measurement of carbon monoxide (CO) in exhaled air. In the respiratory tract CO synthesis occurs through hemoxygenase enzymes, in proportional quantity as to local inflammatory process. Tobacco-addicted usually presents high levels of CO in exhaled air. Approximately 24 hours after smoking cessa- tion, CO exhaled levels start to fall, indicating pulmonary functional recovery. Exhaled CO concentration of non- smokers is below 10 ppm (parts per million)24. Some researchers use portable devices to quantify exhaled CO, not only for focused clinical evaluation, but also to encourage the patient during smoking cessation program enrollment24. A National Study Haggsträm et al. (2001)20 assessed 169 smokers which voluntarily enrolled in a university smoking ces- sation service. Most people who searched for assistance were women (67%), median age (mean 46 years), high educational level and motivated to quit smoking due to respiratory disorders (85%). Nicotine dependency was moderate in 50% of the cases, mild in 27% and severe in 22%. Proposed treatment was cognitive-behavioral psy- chotherapy for mild cases, psychotherapy associated with pharmacotherapy (or bupropion 300mg/day or NRT) for moderate cases, and psychotherapy associated with phar- macotherapy (bupropion 300mg/day plus NRT) for severe cases. About 30% of smokers abandoned the program in the first week. At the end of the study, 124 individuals remained in the program; 49% had quit smoking and 13% significantly reduced cigarette consumption. Success rate in smoking cessation was: 23% in psychotherapy, 50% in NRT, 59% in bupropion use and 59% in combined use of bupropion and NRT. Only one patient had to interrupt the use of bupropion due to adverse effects. DISCUSSION Ironically, after five centuries, tobacco has gone from a medicinal plant –used even to prevent cancer – to one of the worst world public health issues. Nicotine dependency is currently one of the most common chronic diseases in the population24. Differently from alcohol and illicit drugs, nicotine does not cause acute conditions due to overdose in addicted individuals. Also, it does not lead to aggressive behavior or worsens the psychomotor performance in car driving and ma- chine operation. Therefore, nicotine dependency is less shocking to society than alcohol dependency and other psychoactive drugs. Exceptionally, tobacco addicts are seen as inconvenient or dangerous – although, there is risk to accidentally burn furniture, clothes, tablecloths or mattresses and causing disastrous fire. On the other hand, an increasing number of people show their disgust to tobacco and to passive smoking. In public places, where smoking is still not prohibited by law, smokers’ segregation is commonly seen. These measures protect non-smokers, although they are not effective to solve nicotine dependency. Governmental campaigns against smoking have been intensified in the last decade, especially through the media and the warnings printed on cigarette packs. 826 BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY 71 (6) PART 1 NOVEMBER/DECEMBER 2005 http://www.rborl.org.br / e-mail: revista@aborlccf.org.br However, around ¼ of the Brazilian population is nicotine- dependents and is subjected to the morbimortality caused by tobacco4. Presumably, effective anti-tobacco advertis- ing is useful to make people aware of tobacco negative effects on health, although not sufficient to eliminate nicotine dependency. Most tobacco addicts are aware of cigarettes harms and want to quit smoking8. However, overcoming prac- tical challenges to achieve this goal include: 1) lack of medical diagnosis on nicotine dependency; 2) abstinence discomfort; 3) insufficient number of smoking cessation supportive services and free distribution of medicine by the public health system. It is difficult to compare scientific studies outcomes related to efficacy of smoking cessation. Several factors must be considered, such as: patients’ cultural and socio- economic features, reasons for their enrollment on smok- ing cessation program (spontaneous attitude or disease, such as cancer and COPD), nicotine-dependency grade, follow-up period and criteria to assess treatment success rate (objective or subjective). Invasive treatments due to smoking complications, for instance, have great influence on smoking cessation. Laryngectomized patients due to cancer treatment have a two-fold probability of smoking abstinence than those treated with radiotherapy only3. According to the literature, bupropion is effective in nicotine-dependency treatment, however there are several clinical conditions that contraindicate its use2,4,8. Presence of side effects is relatively significant, leading to dosage reduction or drug discontinuation in about 38% of the cases16. Nicotine replacement therapy presents good out- comes when associated with bupropion, although it also has limitations, besides not being considered for patients with severe cardiovascular diseases4. Acupuncture is a controversial method for smoking cessation23, especially because western Medicine has not sufficient knowledge on this technique. Scientific occiden- tal literature tends to consider it innocuous for smoking cessation treatment, although, when practiced by a skilled physician, the positive effects of acupuncture cannot be denied. Moreover, effectiveness mechanisms of acupunc- ture remain unknown and require thorough research. CLOSING REMARKS Otorhinolaryngologists must be aware of available therapeutic modalities for nicotine dependence. Scientific knowledge, in addition to sensitivity and keenness will allow the physician to choose the most adequate and mo- tivating way to encourage patients to quit smoking, reduce unpleasant symptoms of abstinence and avoid relapses. 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Smoking cessation from office to bedside. Postgrad Med 2003; 114: 45-54. 15. Tonnesen P, Tonstad S, Hjalmarson A, Lebargy F, Van Spiegel PI, Hider A et al. A multicentre, randomized, double-blind, placebo- controlled, 1-year study of bupropion SR for smoking cessation. J Int Med 2003; 254: 184-92. 16. Kolber M, Spooner GR, Szafran O. Adverse events with Zyban (bu- propion). CMAJ 2003; 169: 103-4. 17. De Graff Jr. AC. Pharmacologic therapy for nicotine addiction. Chest 2002; 122: 392-3. 18. Marlow SP, Stoller JK. Smoking cessation. Respir Care 2003; 48: 1238-54. 19. Brasil. Ministério da Saúde. Instituto Nacional do Câncer (INCA). Abordagem e Tratamento do fumante - Consenso 2001. Rio de Ja- neiro, INCA, 2001, 38 p. 20. Haggsträm FM, Chatkin JM, Cavalet-Blanco D, Rodin V, Fritscher CC. Tratamento do tabagismo com bupropion e reposição nicotínica. J Pneumol 2001; 27: 255-61. 21. NIH Consensus Development Panel on Acupuncture. Acupuncture. JAMA 1998; 280: 1518-24. 22. He D, Medbo JI, Hostmark AT. Effect of acupuncture on smoking cessation or reduction: an 8-month and 5-year follow-up study. Prev Med 2001; 33: 364-72. 23. Linde K, Vickers A, Hondras M, Riet G, Thormählen J, Berman B et al. Systematic reviews of complementary therapies - an annotated bibliography. Part 1: Acupuncture. BMC Complement Altern Med 2001; 1: 3. 24. Balbani APS, Montovani JC. Monóxido de carbono endógeno e as vias aéreas. Rev Bras Alergia Imunopatol 2002; 25: 116-21. 25. Britton J, Jarvis M, McNeill A, Bates C, Cuthbertson L, Godfrey C. Treat- ing nicotine addiction. Am J Respir Crit Care Med 2001; 164: 13-5. Methods for smoking cessation and treatment of nicotine dependence INTRODUCTION Literature Review Nicotine Pharmacology Nicotine actions Nicotine Chemical Dependency Treatment of Nicotine Dependency Patient and Family Counseling Pharmacotherapy First-line Therapy Bupropion Nicotine Replacement Therapy (NRT) Second-Line Therapy Other therapies Acupuncture Cognitive-behavioral Therapy and Self-support groups Assessment of Response to Treatment A National Study DISCUSSION CLOSING REMARKS REFERENCES work_2bo5gpp6gnejrimsjeywqboft4 ---- Mediterranean Sea Becoming Cleaner NOTES, NEWS & COMMENTS Mediterranean Sea Becoming Cleaner That the Mediterranean has never been more 'swimma- ble' was the view expressed recently by scientists and offi- cials meeting in Athens, Greece, at the Mediterranean anti- pollution headquarters of the United Nations Environ- ment Programme (UNEP). 'If you travel around the basin and take a good look, you see lots of progress in making the swimming waters, the sandy beaches, the shellfish and their breeding waters, cleaner, safer, and healthier', asserted Aldo Manos, the impressive Italian who directs the coor- dinating Unit of UNEP's Mediterranean Action Plan (MAP). 'Take municipal sewage, for example. At least 30% of it is now properly treated and piped out to sea where it does no harm. Indeed, it does some good as it feeds the fish. Only a few years ago barely 10% of Mediterranean municipal sewage received any treatment. Several major cities are currently constructing sizeable treatment facilities. For example, municipal authorities are building an immense sewage treatment plant on the island of Psitalia for the four million inhabitants of Athens and its suburbs. The city of Istanbul has launched a $200 million project to clean up the once-glorious, now-inglorious, Golden Horn. This means preventing the dumping of raw sewage, industrial waste, and offal of slaughter-houses, into the sea.' Aldo Manos continued: 'Recently, UNEP sent a mission to Alexandria to explore ways and means of disposing safely and effi- ciently of the Egyptian city's sewage. One option is by very long pipelines out to sea, another is treatment on land and use of purified wastewater for irrigation to reclaim the desert.' Further Examples of Improvement Numerous other examples could be cited, reflecting a gradually-changing new mentality among the peoples of the Mediterranean. Almost a decade ago the town of Neum in southern Yugoslavia decided to build a complex of coas- tal hotels with 15,000 beds. Sewage was to be discharged in the middle of Mali Ston Bay at an estimated cost of $1.5 million. But the magnificent resort of Dubrovnik, only 60 kilometres to the east, had been planning to breed shellfish in Mali Ston Bay, as the Romans did 2,000 years ago, and they opposed Neum's hotel-and-sewage plan. In April of this year, Dubrovnik and Neum signed an agreement, call- ing for a much longer, much more expensive, pipeline (17 kilometres in length and costing $5 millions) that will cross the peninsula and, after treatment, discharge sewage into the open Adriatic. So, Neum will construct its hotels and Dubrovnik will increase its shellfish production to some 40,000 tonnes a year. At last year's meeting in Genoa to commemorate 10 years of Mediterranean Action Plan (MAP) activities, Mediterranean governments pledged themselves, as a priority, to 'build sewage treatment-plants in all cities around the Mediterranean with more than 100,000 inha- bitants, and appropriate outfalls and/or appropriate treat- ment plants for all towns with more than 10,000 inhabi- tants, during the second Mediterranean decade'. There are today around 90 Mediterranean coastal cities with a popu- lation exceeding 100,000, and approximately 600 with populations of more than 10,000. Another of the Genoa meeting's '10 targets by 1995' is the 'establishment of reception facilities for dirty ballast- waters and other oily residues received from tankers and ships in ports of the Mediterranean'. Some 300 million tons of petroleum are shipped across the Mediterranean to and from 18 oil-handling ports. Only 9 or 10 of them possess adequate reception facilities. 'Ad- mittedly there's still a great deal to be done in the fight against Mediterranean coastal pollution, and talking about the next decade discourages some people because it seems such a long time', concedes Aldo Manos. 'All right, I won't defend the indefensible delays in implementing the Medi- terranean Action Plan by saying that Rome wasn't built in a day. Yes, it is taking too long. We're all impatient, but we are definitely making progress.' Some more examples of advances are that 'between 1983 and 1985, Spain spent 7 [thousand million] pesetas (about US $40 millions) on beach protection or improvement, resort access roads, pedestrian paths, and other environ- mentally-sound projects. Almost five times that amount was expended between 1975 and 1985 on water-supply, sanitation, and sewage networks, for 181 Spanish Mediter- ranean communities. The vast majority now have ad- equate facilities. If you go to a beach in the south of Cyprus, you find at 100-yards' [91.4 m] intervals giant oil-drums, painted in attractive colours and converted into trash- barrels. No one has any reason or excuse to litter the beach. And they've installed proper toilet facilities: that's a sine qua non for beaches where families go for the whole day.' The Senior Marine Scientist at the UNEP Mediterranean headquarters, Dr Ljubomir Jeftic, is also optimistic about the way things are going—even if he, too, is disappointed by the slowness of the action. 'For the first time, at Genoa last year, the Mediterranean governments finally agreed on temporary environmental quality criteria for their bathing waters. They adopted the World Health Organization (WHO)-UNEP standards based on a maximum [concen- tration] of faecal [coliform Bacteria]. True, the criteria may not be perfect but I consider going from no common stand- ards to a common standard for safe swimming-waters a great leap forward for Mediterranean countries', said Dr Jeftic. Eighteenth Mediterranean Coastal State Ready to Join? Incidentally, for the past 10 years most stories about Mediterranean pollution meetings and activities have re- ferred to the presence or the participation of' 17 of the 18 Mediterranean coastal States'. Albania was never to be seen; but in Genoa last autumn, two Albanian observers were present. It is entirely possible that Albania will join its 17 'neighbours' in the Mediterranean anti-pollution... pro- gramme within the next year. Already a remarkable exam- ple of how environmental concern can overcome political conflict, the Mediterranean may soon offer an even more extraordinary picture of environmental unanimity. Dr Jeftic, a Yugoslav scientist who has worked in Zagreb, the University of Warsaw, the University of Kansas ('where the nearest sea was one of wheat'), and the Brook- haven National Laboratory on Long Island (USA), pointed to the substantial development of national pollution mon- itoring programmes in the 17 MAP countries: 'Libya and Egypt have two new monitoring programmes. We expect to sign four agreements for programmes within six months with Greece, Turkey, Syria, and Tunisia. Seven countries (Algeria, Morocco, Cyprus, Malta, Lebanon, Israel, and Yugoslavia) have ongoing programmes. France, Italy, Spain, and Monaco, are preparing theirs. 'I think it is important to keep in mind that all these anti-pollution activities do not produce immediately visible results. It takes time for them to be seen and felt.' 'Another very important activity we have just agreed on is a 10-years' plan to assess all the substances on the 'black' 267 Environmental Conservation, Vol. 13, No. 3, Autumn 1986—© 1986 The Foundation for Environmental Conservation—Printed in Switzerland. https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0376892900036377 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:29, subject to the Cambridge Core terms of use, available at https://www.cambridge.org/core/terms https://doi.org/10.1017/S0376892900036377 https://www.cambridge.org/core 268 Environmental Conservation and the 'grey' lists of the treaty on land-based sources of pollution—not just to assess their sources, levels of pollu- tion, and effects on people and marine life, but to propose concrete measures to do something about them. We are no longer merely furnishing facts. The substances I am talking about include, among many others, used motor oil, mer- cury, cadmium, radioactive ones, pesticides and other organic pollutants on the 'black' list and, on the 'grey' list, lead, zinc, tin, chromium, silver, crude oil, detergents, and pathogenic microorganisms.' Shipping Industry Involvement The European Community has been a very active parti- cipant in the Mediterranean Action Plan. Recently it spon- sored a workshop on the shipping industry and the marine environment, in Athens, that was organized by the Hell- enic Marine Environment Protection Association (HEL- MEPA). 'When we set out to interest shipowners, captains, and crews, in protecting the sea from pollution, I was very sceptical', admitted Dimitris Mitsatsos, Director-General of HELMEPA. 'Well, in only four years we have enlisted 400 ships, over 3,000 officers and sailors, and most Greek shipowners. We have succeeded in very slowly changing the mentality of thousands of seafarers, and in getting through to their consciences. It is a measure of our success that the Athens workshop [in June 1986], under EEC aus- pices and with the participation of Beate Weber, the chair- woman of the Environmental Committee of the European Parliament, urged 'the general adoption and extension of HELMEPA's approach to merchant marines on a world- wide basis'.' The Director of UNEP's MAP, Aldo Manos, mentioned, as another indication of Mediterranean governments' seri- ousness, the ratification by Greece on 20 June of the treaty on Specially Protected Areas. This brought the number of ratifying countries to six plus the European Community, as a result of which the treaty will enter into force very short- ly- PAUL EVAN RESS Regional Office for Europe United Nations Environment Programme Avenue Trembley 16 Petit-Saconnex Geneva, Switzerland. Environmental Bankruptcy in Haiti Christopher Columbus described Haiti as 'Filled with trees of a thousand kinds and tall'. But no longer is it so; indeed, if present trends continue, this small Caribbean island nation on the doorstep of the USA could be com- pletely deforested within fifteen years. Haiti is experiencing an environmental crisis as severe as are those of the African countries bordering the Sahara. Five years ago, FAO estimated that Haiti was losing the fertility of 6,000 hectares (ca 15,000 acres) of land each year. The rivers and streams are choked with mud, and far out to sea beyond the capital, Port au Prince, the water is stained brown with mud. Rapid population growth, hurri- canes, and frequent droughts and flooding, have all contributed to the crisis, but the real blame lies with decades of neglect under the regimes of the Duvaliers, both father and son. Evidence of that mismanagement is seen on the border with the Dominican Republic, where, on the Dominican side, there is thick forest, whereas on the other side the hillsides are bare. Neglect of investment in agriculture, forestry, and sources of energy, has left the vast majority of Haitians with no alternative other than to fell the trees and over-use the land. Haiti is one of the few countries where agricultural productivity is actually declining. With fertile land becoming increasingly scarce, more and more villagers are turning to firewood collection. Virtually all the trees around the capital have been cleared, and the only significant stands left are in the remoter areas in the northern part of the island; but now these, too, are rapidly being felled. According to a World Bank Survey, the cur- rent 2.4 million cubic metres' deficit of firewood is destined nearly to treble by the turn of the century. There are few energy alternatives. An American-built hydroelectric dam at Peligre in the mountains near the Dominican border is clogged with silt and operating at only one-quarter of its intended capacity. A recent expert survey concluded that it may have to shut down if siltation is not stopped. Many villagers have no alternative other than to leave the land—the drift to the slums of Port au Prince has become a torrent. Virtually everyone you talk to in the slums is a recent arrival, their dream being to escape to the United States. The US Coastguard now keeps a permanent flotilla off Haiti, to intercept illegal immigrants who are prepared to make the risky crossing to Florida. A massive relief effort is needed to help the post-Duval- ier Government to begin the work of rehabilitation—by no means a hopeless task, as for example under a US AID $8 million scheme, volunteer groups have encouraged villag- ers to plant 17 million trees in the past four years. Of those trees about 20% survive, which is a very respectable rate. But it is going to take more than tree-planting to rescue Haiti from such a long-term decline. According to UNI- CEF, 73% of all Haitian children of school age are suffering from some form of malnutrition. Sooner rather than later, the new Government will have to turn far more of its attention than currently to improving the lot of the vast majority of Haiti's poor, who must live with the day-to-day realities of environmental bankruptcy. ROBERT P. LAMB, Director TVE Television Trust for the Environment 46 Charlotte Street London WIPILX England UK. New Northern Look The Arctic Institute of North America, now of the Uni- versity of Calgary, is updating its newsletter Information North, which it has published over the years as an informal vehicle for keeping its subscribers informed. In the past, such newsletters tended to focus on membership matters, and accordingly to be cast in a chatty framework with sto- https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0376892900036377 Downloaded from https://www.cambridge.org/core. 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Page Tools Show pagesource Old revisions Backlinks Back to top work_2ffpinb73ze6xhcemfxydzdbhu ---- Introduction Science in Context 12, 1 (1999), pp. 3-6 Introduction* Much has been written on the present and future interactions between science and law, less so of their past. This issue brings together scholarship from history, anthropology, philosophy, and social studies of science in the attempt to add a much-needed historical perspective to the important discourse concerning the relations between science and law. The issue consists of nine papers arranged in chronological order, except for the two synthetic papers that open and close it. The papers vary widely in subject and approach. However, out of this diversity several themes emerge. Scientific expert testimony has been a cause of much concern lately in Anglo- American courts. It is a commonplace today that "junk science" introduced into the courts by partisan scientific experts presents a dramatic new problem that demands immediate redress. However, in the opening article, I show that discon- tent with scientific expertise has existed ever since there were scientific expert witnesses in the courts. Tracing the development of scientific expert testimony in eighteenth- and nineteenth-century England, I demonstrate that the debate over the meaning of conflicting scientific expert testimonies and the ways to resolve the conflicts had acquired by the mid-nineteenth century all the features that today are blithely assumed to be new. The courts' ability to handle complex science-rich cases has been constantly called into question. Critics have argued that judges cannot make appropriate decisions because they lack technical training, and that jurors do not comprehend the complexity of the evidence they are supposed to analyze. Paternity cases in which men were determined to be fathers, even though blood tests could prove that biological paternity was impossible, have served as a much-cited example of the judicial misuse of science. However, analyzing the role paternity blood tests played in divorce cases throughout the twentieth century, Shari Rudavsky shows that judicial distaste for science in paternity cases does not come from a failure to understand science. The goals of the law, Rudavsky reminds us, are not always consistent with those of science. And when the interest of a child is at stake, the courts often prefer a social definition of paternity to a biological one. The courts, then, are not neutral gatekeepers that simply exclude from the courtroom unreliable scientific testimony, but rather active partners in the pro- duction and maintenance of credible scientific evidence. As such, the courts prefer * It gives me great pleasure to acknowledge the generous support of Dibner Institute for the History of Science and Technology, without which this interdisciplinary effort would not have reached fruition. use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0269889700003288 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:27, subject to the Cambridge Core terms of https://www.cambridge.org/core/terms https://doi.org/10.1017/S0269889700003288 https://www.cambridge.org/core TAL GOLAN sometimes to ignore certain kinds of legitimate scientific evidence, while privileging other sorts of a more questionably scientific nature. Fingerprint evidence, perhaps the most popular sort of scientific evidence in the twentieth century, is a good example. The community of fingerprint experts was always troubled by the lack of an easily articulated scientific foundation for its practices. Tracing the century-long debate over the "scientific" nature of fingerprint evidence, Simon Cole describes how the community of fingerprint experts was able to keep its lingering disagree- ments private, thereby maintaining its authority in the courtroom. In doing so, Cole suggests, fingerprint experts were allowed remarkable leeway by courts who were interested in preserving a credible technique for criminal identification. The legal application of scientific evidence involves not only the determination of its scientific status but also of its legal status. For example, the legal status of medical images has always been fraught with innate contradictions. On the one hand, they seem to allow the jury to eliminate the witness and see the "bare facts" with their own eyes. On the other hand, they have been recognized as prone to deceit and manipulation. Understood the first way, medical images are primary evidence, affording the greatest certainty about what they depict. Understood the second way, they are, at best, secondary evidence, only resorted to out of necessity in cases where primary evidence is insufficient. Addressing the history of medical images in the courts, from late nineteenth-century radiography to twentieth- century computerized tomography (CT) and positron emission tomography (PET), Joseph Dumit describes the ways in which these images came to be understood in court. The late twentieth-century interpretation of intricate representations as real and objective, Dumit suggests, exacerbates the innate contradictions that have always accompanied the use of scientific images in the courts and brings the issue to a point of crisis. Science has influenced not only legal fact-finding and decision-making proce- dures but also legal education. During the nineteenth century many jurists hoped that, like geometry, the law too could be reduced to first principles from which all necessary consequences could be deduced. Others yet hoped that, like geology and biology, the law could be explained developmentally through the history of its empirical content. Howard Schweber examines the particular conceptions of "science" in antebellum America that were incorporated into the idea of "legal science." In the 1870s, Schweber suggests, these conceptions were incorporated into Christopher Columbus Langdell's famous case method, which continues to influence both legal education and jurisprudence to this day. Of course, law has affected science no less than science has affected law. For example, the conception of scientific information as a tangible asset ushers in the whole legal apparatus designed to deal with issues such as who owns it, how is it transferred, and who is allowed to use it. We are accustomed to think of legal disputes over the ownership of scientific knowledge as a relatively modern pheno- menon. However, as James Voelkel demonstrates, such disputes stretch back at least to the early-modern period. Describing a legal dispute during the opening use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0269889700003288 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:27, subject to the Cambridge Core terms of https://www.cambridge.org/core/terms https://doi.org/10.1017/S0269889700003288 https://www.cambridge.org/core Introduction years of the seventeenth century between Johannes Kepler and Tycho Brahe's heirs over the right to capitalize on Tycho's astronomical observations, Voelkel shows how the legal dispute determined Kepler's choice of research, and, more particularly, the way in which that research was presented in his revolutionary Astronomia Nova (1609). With the advent of twentieth-century biotechnologies, the transformation of science from intangible knowledge into tangible commodities has taken a bizarre turn. Revisiting the much-critiqued case of Moore v. Regents of the University of California, in which John Moore claimed property rights in a patented cell line made from his spleen, Hannah Landecker maps the nexus of science, law, and commerce in which human tissue is transformed into a patentable cell line. Tracing the intertwined development of the relevant scientific and legal discourses, Lan- decker shows how legal reliance on scientific explanation can lead to uncritical adoption of ethical and political biases already built into the objects and practices of contemporary biotechnology. The negotiation concerning the proper relations between legal and scientific authorities, and how much deference science should command in relation to other modes of knowledge are at the center of Jessica Riskin's paper. Riskin describes a legal dispute in 1780 France between an amateurphysicien and his neighbors who demanded that he remove a lightning rod he had put on his chimney. This most local of disputes turned into a three-year court battle concerning the proper relations between facts and theory, between center and periphery, and between legal and scientific authorities. The case launched the career of a young and unknown lawyer, Maximilien Robespierre, who argued successfully against the need for expert mediation between the judges and the facts. A decade later, Riskin suggests, this view became the official policy of the newly founded Republic, leading to the abolishment of scientific expertise from French officialdom. Finally, in the paper that closes the volume, Yemima and Hanina Ben-Menahem examine the philosophical bases for our expectations that science and law provide uniquely correct answers to the problems they address. Comparing the different ways in which philosophers of science and philosophers of law have approached this requirement of "one uniquely correct answer," Yemima and Hanina Ben- Menahem suggest significant analogies between the two disciplines, and offer important insights into their practices and philosophies. Both law and science, Yemima and Hanina Ben-Menahem conclude, have developed surprisingly similar strategies to cope with indeterminacy, thereby preserving the legitimacy of their fact-finding and decision-making processes. The relationships between science and law over the past centuries have been varied and complex. As the essays in this volume demonstrate, the study of this relationship allows us to address the ways in which society in different epochs has constructed its ideas about who is entitled to represent nature, what constitutes legitimate scientific and technological knowledge and practices, the criteria by which these are evaluated, and the social role of expertise — in short, how we have use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0269889700003288 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:27, subject to the Cambridge Core terms of https://www.cambridge.org/core/terms https://doi.org/10.1017/S0269889700003288 https://www.cambridge.org/core TAL GOLAN understood and deployed truth, justice, knowledge, proof, and property. More research is needed before the interplay of science and law is sufficiently elucidated. It is my hope that the papers in this volume suggest the richness of this picture that has yet to emerge. Tal Golan Dibner Institute for the History of Science and Technology Massachusetts Institute of Technology use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0269889700003288 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:27, subject to the Cambridge Core terms of https://www.cambridge.org/core/terms https://doi.org/10.1017/S0269889700003288 https://www.cambridge.org/core work_2hofxlrnifb5fay2so2ux4b52a ---- IN HER INTRODUCTION TO THE EN GLISH INSTITUTE’S E- BOOK ON PERI- ODIZATION, THE EDITOR, VIRGINIA JACKSON, REMARKS ON THE ABILITY of its “digital format” to invite innovative ways of interacting with texts. Marshall Brown’s article in the book, for example, allows readers to hear Joseph Haydn’s music while they read nineteenth- century literature, giving them an immediate understanding of the musical metaphors Brown uses for describing literary history. Our contemporary presence and capabilities in the digital world, Brown suggests, may help us to understand periods as “linked episodes within the rolling !ood of time,” enabling what Jackson describes as “a literary historical process” that “is not progress but wave, not transcendence” but, as Brown writes, “the metrics and bar lines shaping the pulse of history’” (Jackson, par. 4). "e authors of On Periodization suggest a practice of periodization that allows for si- multaneities: “a new plane of historicity on which several tempo- ralities unfold at once” (Jackson, par. 4). "is conception of time is made possible by the present moment, the (relatively) new technolo- gies we have in our midst, through which this e- book is expressed. "is “new plane” of simultaneities re!ects the primacy of the present in that the technologies we use are actively shaping how we experi- ence literature and literary history (Martin 153–56). Furthermore, while chronological periodization can dis- embed events from their places, our process of reading rhizomically in the digital world may move us to reconsider the primacy of place. "e pulsing wave may leave us wanting, but as scholars includ- ing Stephanie Fitzgerald, Hillary Wyss, Timothy Powell, and Wai Chee Dimock have suggested, other metaphors may enable us to break the vexing boundaries and narratives of progress inherent in (or inherited from) the process of periodization. As Dimock notes, many people still assume that the linear division of time—repre- sented by minutes and hours, as well as periods and eras—is an onto- logical truth, as if time were “a measuring tape, with #xed segments” that by its own force permeates all spaces over which we impose it. LISA BROOKS is John L. Loeb Associate Professor of the Humanities at Harvard University and author of The Common Pot: The Recovery of Native Space in the Northeast (U of Minnesota P, 2008). theories and methodologies The Primacy of the Present, the Primacy of Place: Navigating the Spiral of History in the Digital World $%&' ()**+& [ P M L A ,-. [ © / -0 / 12 3 4 5 67859 : ; < :=><=5 < ? ?7 @A <3 A7: 7B < 6 59 A@ < ] However, in concert with many Indigenous studies scholars, Dimock questions that as- sumption, revealing that in other places be- yond the “Western world” “a very different ontology of time prevails.” For her, it is the image of the spiral, so prevalent in the litera- tures of the Americas, that is most compel- ling (2; see also Cohen, “New En gland” 315). This spiral is embedded in place(s) but revolves through layers of generations, re- newing itself with each new birth. It cannot be !xed but is constantly moving in three- dimensional, multilayered space. It allows for recurrence and return but also for trans- formation. Its origins lie in ancient worlds, but it moves through our own bodies in the present, perhaps with a sense of irony. As the Muskogee poet Joy Harjo writes, “[W] hen the mythic spiral of time turned its beaded head and saw what was going on, it snapped” (In Mad Love 54). While a romantic reading inherited from salvage ethnography might suggest that the spiral’s “beaded head” was cut o" by modernity, a reading inspired by recent Native literary criticism might see the spiral as a dancer who “snapped” her beaded head !ercely, suddenly directing her gaze to- ward the incredulous world swirling around her. The phrase implies a break, a need to pay attention, a need for considered analy- sis from the perspective of the spiral, which embraces simultaneity (Fitzgerald and Wyss 272; Womack, Red 250–51; Kolosov 47). As Dimock notes, scholars such as Bene- dict Anderson and Anthony Gibbons have ar- gued that the linear measurement of time is “a mark of modernity, linked to the rise of the nation- state and the rule of the mechanical clock” (2). However, as Linda Tuhiwai Smith points out, the “emplotment” of time may also be a mark of colonization, whereby the concept of “modernity” parallels the sweep- ing narratives of “civilization” and “prog- ress” (55; see also Powell, Weems, and Owle 4–5; Wishart 307). As Dimock acknowledges, many colonized peoples retain alternative conceptions of time that share space, albeit unequally, with the ticking of the clock, an instrument that came to be known in the Western Abenaki language as papeezokwazik, “that thing which makes much noise and does nothing useful” (J. Bruchac 9; see also Laurent 290). It may be that in the digital “age,” if we choose to retain such a label, the measuring tape of time will become decreasingly useful and, perhaps, increasingly (self)destructive. This essay presents an opportunity to raise questions, to expose the “!ssures” that may open when the primacy of the present— that is, the possibilities of the digital world and the rise of Indigenous studies in global networks—is put in conversation with the primacy of place, particularly the “Ameri- can” landscape that many readers of this vol- ume now inhabit (Martin 154). What would it mean to privilege place when discussing periodization, to consider, as the geographer David Wishart does, that “period” and “re- gion” are deeply linked narratives? What dif- ferent shape might literary history take if we account for distinct conceptions of time that arise simultaneously from particular places? How might Indigenous methodologies help answer some of the vexing questions that lit- erary historians ponder in our present world? Literary history did not emerge on this continent when Christopher Columbus ar- rived in 1492. As Colin Ca l loway w rote, “What Columbus ‘discovered’ was not a ‘new world’ but another old world” (14; see also Anderson 286). Multiple forms of textualities emerged from this “old world,” literary me- dia deeply intertwined with oral narratives, which in the last several centuries have also taken the form of alphabetic print. David Cu- sick’s History of the Six Nations (1825), for ex- ample, is one of several alphabetic texts that recount the narratives of the Haudenosaunee (Iroquois) Confederacy, drawing on wampum belts, written accounts by Haudenosaunee scribes, and extended oral narratives relayed in the longhouse.1 Cusick allows for multiple 1 2 7 . 2 ] Lisa Brooks  t h e o r ie s a n d m e t h o d o lo g ie s reckonings of periodization in his narrative, even as he calls our attention to the recent- ness of Columbus’s voyage. For example, in telling the story of the “stonish giants,” he relates that this “invasion” of “the country” by a nation from the Mississippi River oc- curred “about two hundred and fifty win- ters since the people left the mountain,” or “perhaps about 1250 years before Columbus discovered the America[s] ” (20). !is account of an actual battle is layered with narratives about an ongoing, spiraling contest between "gures of the upper world of the sky and the lower world of the waters, which spread rhi- zomically into the past and future, as well as through networks that cross the continent. To interpret this one episode in Cusick ’s narrative with insight requires reading rhi- zomically within the extensive narratives of the Haudenosaunee Confederacy and the re- lated oral traditions and graphic media of the continent. Our intepretive travels would take us east to the Wabanaki coast, where petro- glyphs of the same "gures can be viewed in stone; west to the Mississippi, where iconog- raphy of the upper and lower worlds appears in pottery and earthworks; north to the An- ishinaabe country, where similar stories are mapped in birchbark scrolls; and south to Mesoamerica, where related narratives are carried in codices, sung in poetry, and in- scribed on painted walls (Brotherston; Mann; Mann and Fields; Quilter et al.; Reilly and Garber; Townsend and Sharp; Tedlock; Popol Vuh). We might be led to these places by con- temporary literature, tribal history, or “wam- pum chronicles” on the Web (Bonaparte). Scholars have only recently begun to turn their attention to the “wealth of literary me- dia” in the Americas and to the ways in which these media and their associated oral litera- tures might redirect our questions toward new interpretative possibilities (Brotherston 4). What will American literary history look like if we take seriously Indigenous frame- works for reckoning time and conceiving of literature? To place Cusick ’s narrative in what Roger Echo- Hawk terms “Ancient American history,” for example, we would be compelled to consider Haudenosaunee “epochs” as relayed in the longhouse, as Bar- bara Mann does, and, as Gordon Brotherston does, to consider the text’s relation to Quiché Mayan “worlds” and to the larger “Mother Corn era,” proposed by Echo- Hawk, which encompasses the emergence of the Haude- nosaunee Great Law during the agricultural revolution and ties the narrative to the emer- gence of the Quiché nation as the “people of corn,” as related in the epic Popol Vuh. What would it mean to acknowledge that time does not necessarily roll over us like a #ood or a measuring tape? What if time also operates like a spiral? What would it mean to think in terms of “worlds” rather than “periods”? How might these alternative frameworks help us to work “creatively,” as Timothy Powell asks, to “free” American literary history “from the taxonomic grid of chronological time that commences with the moment of coloniza- tion?” (Powell, Weems, and Owle 8). Instead of answering these questions in full, I hope to raise possibilities, examples that might cause us to “snap” our heads and pay close attention to “what [is] going on” around us. Let me offer an example drawn from a place I have come to know well, Harvard Yard, at the time of the college’s origins, when the #edgling university was located just downriver from the Massachusett Saunk- skwa’s town of Missitekw.2 Here, in the pre- paratory school beside Harvard Hall and the Harvard Indian College, En glish and Indian students learned the “truth” about time from their primers, including Thomas Shepard’s Catechism. In answer to the question “How may it be proved that there is a God?” stu- dents would have repeated by rote, “From time, for we see that months come before years, and weeks before months, and dayes before weeks, and houres before dayes . . . and a minute of time before an hour, and there-  The Primacy of the Present, the Primacy of Place [ P M L A t h e o r ie s a n d m e t h o d o lo g ie s fore there must necessarily be some minute of time before the world began, & therefore a God who gave it this beginning.” !e primer relayed a tricky but potentially persuasive form of circular reasoning: the existence of linear, divided time was a fact of the world, and since it could presumably be observed by all humankind, the movement of time dem- onstrated the orderly vision of Jehovah and the world he created. !erefore, time was an a priori creation of the divinity, and the divin- ity could be witnessed in chronological time. Yet Wa mpa noag students li ke Ca leb Cheeshateaumuck and Joel Iacoomes, as well as En glish missionary students like Matthew Mayhew, would have read and recited a Wam- panoag version of the same question. “Oohgôk je korâmen neh átta Mandouh?” ‘How prove you that there is a God?’ the bilingual “Some Helps for the Indians” asked (Clark 343). Here Mandouh referred to an Algonquian conception of ambivalent, ambiguous power that moves through all beings. Among the rote answers o"ered by the text was the reply “there is Mandouh common to all men, nor is it changed by the changes of times; therefore it must arise from some light which is com- mon to all men” (Clark 344). !is depiction ref lected and reinforced the presence of an inde#nable spirit or “light” that inhabited a spiraling, spatialized conception of “deep time,” permeating all spaces and temporali- ties (M. Bruchac 56; see also Dimock 6; Pow- ell, Weems, and Owle 3; Silverman 26–28, 59). T he D a kot a nove l i s t (a nd Ha r v a rd alumna) Susan Power demonstrates a similar conception of layered time in her compelling short story “First Fruits,” based on the his- tory of the Harvard Indian College. Empha- sizing the primacy of place and the spiral of history, Powers creates a young protagonist steeped in Indigenous history who is seeking to understand a new, seemingly foreign place as a freshman at Harvard College. Although Georgiana Lorraine Shoestring, or “George,” occupies a contemporary moment, a place we share, she pursues a deep relationship with her predecessor, Caleb Cheeshateaumuck. She #nds herself “going out of my way, wan- dering behind Matthews Hall, to that spot where the Indian College once stood” every day, “looking for Caleb” (126). For her the history of the Indian College is an “elusive,” animated space that permeates old buildings and new friendships. George #nds her place at Harvard by imaginatively understanding Caleb’s, and, ultimately, it is writing that al- lows her to #nd “Caleb Cheeshateaumuck ’s elusive spirit” (131). Literature is the vehicle that enables her to travel. Her own writing carries her beyond Har vard ’s halls to Ca- leb’s home on the island of Noepe (Martha’s Vineyard), where his “spirit” has rejoined his family. In one of the most powerful passages in the story, George re$ects, “I was taught to believe that time is not a linear stream, but a hoop spinning forward like a wheel, where ever y t hing is connected a nd ever y t hing is eternal. In this cosmology, I am here be- cause Caleb came before me, and he was here in anticipation of me” (127). !is statement has proven potent, not only for the imagined Dakota student but also for countless Native people who have come through Harvard ’s halls, feeling a deep, if con$icted, connection to the young men who came before them and to the buried histories and descendant com- munities that continue to inhabit this place. Indeed, as George discovers, literature itself embodies the spiral of history. As Di- mock notes, “Literature is the home of non- standard space and time” (4; see also Cohen, “New England” 315). We love fiction for its ability to transport us to imagined places and times without requiring us to follow a strictly chronological path (Martin 155). So why are we compelled to contain literature within the bounds of literary periods? What would it mean to follow paths of intellectual kinship, moving through rhizomic networks of in$u- ence and inquiry? What would Web- based networks of literature look like?3 As Fitzgerald 1 2 7 . 2 ] Lisa Brooks  t h e o r ie s a n d m e t h o d o lo g ie s and Wyss suggest, we might adopt Robert Warrior’s model of “intellectual trade routes,” which already guides our readings of Native American literature, more broadly (Fitzgerald and Wyss 272; Warrior 181). !is process of reading rhizomically “across time,” common in Indigenous studies, enables us to apply the insights of the nineteenth- century Pe- quot author William Apess to contemporary questions of sovereignty, identity, and justice; or to see the ancient Pueblo story of Yellow Woman, as Leslie Silko does, moving through the life of a contemporary woman (Storyteller 55); or to read glyphs and their associated oral traditions as a “map to the next world,” in the words of Harjo’s poetic vision (“Map” 19). The digital world is moving in concert with Indigenous literary traditions, carrying us to a place where we are already reading with simultaneity across intellectual trade routes. Our students do this kind of lateral, rhizomic reading without pause. At least half the texts I assign in my courses are now accessible on the Web, and nearly every question my students pose as they are reading can be answered by pursuing a branch into the digital world. !ey can answer old questions about word de"ni- tions, historical context, author biography, or cultural frameworks instantaneously. !e questions that drove me to the library at 6:00 a.m. while I was in graduate school can now usually be answered, even at 3:00 a.m., by the Web. Texts as rare and fragile as the Eliot Bi- ble, which Caleb Cheeshateaumuck held in his hands, can be viewed as PDF "les. Places can be mapped and viewed by satellite on Google Maps. We can instantly communicate with each other, seeking answers to our most press- ing questions, by e-mail, Skype, or Facebook. Even a technophobe like me can appreciate the possibilities o#ered by the digital world. My students, as one thesis advisee explained to me, were born into this space. !ey do not know a world that is not wired. Sometimes, Web- based intellectual trade routes take us to places unimagined when we began. Some- times, they drive us to distraction. However, they are the reality of our world, perhaps part of the scenario that makes the spiral of time snap her beaded head, at the newness not of modernity but of the ancient networks of thinking renewed in innovative forms. Our globalized, digital world, as scholars including Matt Cohen (Networked Wilder- ness), Jerome McGann, and Walter Mignolo have suggested, may be more like the world in which Caleb lived than we realize. Further- more, as Timothy Powell demonstrates, this space offers “dynamic new possibilities for presenting stories from the Native American oral tradition,” a form not easily contained by “the logic of periodization” (Powell, Weems, and Owle 2). Just as the vehicle of writing enabled George Shoestring to "nd Caleb in an unexpected place, the vehicle of the Web enables us to create spaces for oral traditions that continue to live and evolve within Native communities. In “Native/ American Digital Storytelling,” an online essay that provides its readers with links to digital maps, Web sites, and digital video, Powell allows his readers to view and listen to Freeman Owle, a highly respected Eastern Cherokee storyteller, re- late two signi"cant Cherokee narratives in a contemporary setting, the teller surrounded by books. Owle’s account is not le$ to stand on its own, as an artifact of Cherokee culture. Rather, Powell demonstrates through his analysis the complexity of oral traditions and their operation within multiple temporalities. For example, Powell ’s analysis reveals how Owle’s story of the Great Buzzard and the origin of Cherokee medicinal knowledge use a mode he calls “ancient present tense,” both “going back to the beginning of time” and occurring in the moment of telling (Pow- ell, Weems, and Owle 10; see also Basso 6, 33; Connelly 75). Powell demonstrates that gaining knowledge through interpretation is an ongoing process. The story does not simply relate how an object of knowledge was acquired; rather, it functions as a vehicle  The Primacy of the Present, the Primacy of Place [ P M L A t h e o r ie s a n d m e t h o d o lo g ie s for transmitting knowledge. Furthermore, that knowledge is not contained within the bounds of the story, captured in a book or YouTube clip, but is developed in contempo- rary Wolf Clan women’s interaction with the narrative, as well as with the plants and peo- ple through which the knowledge is practiced in a particular place. Interpretation occurs in multiple media—digital, oral, land- based, material—and through the intimacy inher- ent in the relationship between a healer and her kin. Just as the story operates in multiple temporalities, there are also multiple layers of access and interpretation. Oral traditions such as this story, Powell maintains, “provide a glimpse of vast temporal vistas or what might be called deep American literary history” (Powell, Weems, and Owle 2). “Instead of forcing native story telling into a rigid linear time frame of western ‘history,’” as some anthologies have attempted to do, assum- ing all oral traditions belong to the period be- fore colonization, Powell theorizes “alternative forms of temporality,” which move through Native oral traditions and “more accurately ac- count for the deep time and nonlinear move- ments of indigenous poetics.” His aspiration is that the “critique” and analysis he o"ers, in conversation with tribal historians, elders, and scholars, will “contribute to the ongoing pro- cess of recognizing the Native/ American oral tradition as a point of origin for American lit- erary history” (Powell, Weems, and Owle 3). #is is quite di"erent from proposing that Na- tive American origin stories be included as part of or precursor to American literary history. In this work, Powell suggests a new path for mapping American literary history, a spiraling cycle of emergence in an old place. Like Silko’s character Tayo in Ceremony, he calls American literary history to move through and acknowl- edge its own colonization and the colonization of the land, in order to emerge with new eyes into an old, but always transforming, space. Powell also performs “digital storytell- ing” by leading us through the digital world to the “site” of the Cherokee Nation, where we can view an image of Kituwah, the Cherokee Mother Town, and the “home” page of the contemporary nation, while we are listen- ing to Owle’s telling of the “Kituhwa Mound Story” (Powell, Weems, and Owle 15–16). As Eric Gary Anderson notes, “#e early and the contemporary are close enough to touch and are powerfully intertwined” in such “narrated places” (281). Kituwah is simultaneously the place where the nation and its “laws” emerged, where its oral traditions were inscribed, and from which its national $re was renewed and redistributed every year. It is also the site of contemporary contests. As recently as 2010, the ancient mound was threatened by the planned development of a Duke Energy sub- station.4 Just as they used the printing press to disseminate news and arguments against Removal during the nineteenth century, the Cherokee Nation used the Web to communi- cate with tribal citizens and the general public, stirring opposition to the project, the digi- tal world o"ering new technology to expose threats to the community and its motherland. #e nation is located at once in the deep, ex- tending layers of Kituwah, in Oklahoma and North Carolina, and in the networks of the digital world. With the technology of the Web, Powell’s essay puts us in Cherokee space; like a glyph, the image of Kituwah makes us hold the land and its stories, ancient and contem- porary, in our mind, our wired present spiral- ing us back to the primacy of place. In his essay “#e Presence of Early Native Studies,” Anderson writes, “Known, lived, remembered, and living, the land is quite literally the grounds of Native knowledge, literacy, and textualities” (281). Likewise, in- stead of “theorizing ‘America’ as an ideology or a nation,” Powell seeks to “look beyond the topynym” of “America” to consider a “liter- ary history of the land” (Powell, Weems, and Owle 3). #us, rather than think of American literature as a corpus centering around the emergence of the political body of the United 1 2 7 . 2 ] Lisa Brooks  t h e o r ie s a n d m e t h o d o lo g ie s States, we might consider the vast landscape of textualities that have emerged from this land. To do this, we will need to develop new old modes and methods of interpretation. A major aspect of this education will in- volve acknowledging the land that marks the “grounds” of knowledge and the “nations” where “t he Ancient Word ” has been “ in- scribed” and “implanted” (Popul Vuh 63). If we wish to follow Harjo’s map into “the next world,” we will need to turn our attention not only to textual media but also to map texts in- scribed in place, whether the “Storied Walls” of Mesoamerica and the southwest, the mnemonic petroglyphs carved on rock along great water- ways, or the striking mounds and sculptures built from earth, “achievements in science and aesthetics on a monumental scale,” all of which are deeply intertwined with oral traditions and contemporary literature (Allen 808).5 "e safe- guarding of places like Kituwah is necessary to protect not only the sovereignty and historical heritage of the Cherokee Nation but also the ar- chives of the land. Such earthworks may, as the literary scholar Chad Allen suggests, represent “a still readable form of indigenous writing— not simply on the land but literally through the medium of the land itself—toward nothing less than imagination of possible renewal” (Allen 808; see also Hedge Coke). As many contem- porary Native writers, such as Silko, Louise Erdrich, Allison Hedge Coke, and Harjo, have noted, the land itself can operate as a living text map, steering our ability to navigate an ever- changing world (Silko, “Interior and Exterior Landscapes” 32). Along with the Web, texts, petroglyphs, and wampum belts, the land is part of the “spiral on the road of knowledge” (Harjo, “Map” 20). Like Harjo’s readers, we will have to read a “map printed with the blood of history” and to navigate by our “mother’s voice,” but together we might, as Harjo urges, “make our own map” and emerge into a new old world, spiraling in place (“Map”). NOTES 1. The longhouse of the Haudenosaunee or Iroquois Confederacy represents the longstanding, complex gover- nance system of the confederacy; the geographic space of Haudenosaunee territory; and the physical structure in which councils and ceremonies have traditionally been held. 2. "is Saunkskwa, or female leader, was known also as “Squa Sachem” and “the Massachusett Queen.” "e towns of Cambridge and Charlestown were established with her consent, and she reserved lands for herself and her people on the west side of Mystic Ponds. See, e.g., Paige 383; Shurtle# 254, 394; Frothingham 35–36. 3. "e Rossetti Archive (www .rossettiarchive .org), an online database providing access to all of Dante Gabriel Rossetti’s textual and pictorial works, is an early, compel- ling answer to that question, although it still relies on tra- ditional periodization for part of its organizing principle. For more on the development of the archive, see McGann. 4. Even as I was rereading Powell’s essay, published in 2006, the digital world took me to articles from 2010 about the potential development near Kituwah mound (McKie; Carpenter). "is experience exempli$es the kind of rhizomic reading in which we are constantly engaged. "e crisis was resolved through negotiations between the Eastern Band of the Cherokee and Duke Energy of the Carolinas, which led to the selection of an alternative site for the substation. 5. See, e.g., Womack, Drowning; Erdrich, Books and Tracks; Hedge Coke. See also Allen on Hedge Coke’s Blood Run; Womack, Red, on Harjo and the tie snake; Fitzgerald and Wyss on Erdrich’s Tracks; Quilter et al. WORKS CITED Allen, Chadwick. “Serpentine Figures, Sinuous Relations: "ematic Geometry in Allison Hedge Coke’s Blood Run.” American Literature 82.4 (2010): 807–34. Print. Anderson, Eric Gar y. “The Presence of Early Native Studies: A Response to Stephanie Fitzgerald and Hil- ary E. Wyss.” American Literary History 22.2 (2010): 280–88. Print. Basso, Keith. Wisdom Sits in Places: Landscape and Lan- guage among the Western Apache. Albuquerque: U of New Mexico P, 1996. Print. Bonaparte, Darren. “"e Wampum Chronicles: Mohawk Territory on the Internet.” !e Wampum Chronicles. N.p. Aug. 2009. Web. Oct. 2011. Brotherston, Gordon. Book of the Fourth World: Read- ing the Native Americas through !eir Literature. New York: Cambridge UP, 1992. Print. Brown, Marshall. “"e Din of Dawn.” On Periodization: Selected Essays from the En glish Institute. Ed. Virginia Jackson. ACLS Humanities E- Book. Amer. Council of Learned Socs., 2010. Web. Oct. 2011.  The Primacy of the Present, the Primacy of Place [ P M L A t h e o r ie s a n d m e t h o d o lo g ie s Bruchac, Joseph. Lasting Echoes. New York: Harcourt, 1997. Print. Bruchac, Margaret. “Earthshapers and Placema kers: Algonkian Indian Stories and the Landscape.” In- digenous Archaeologies: Politics and Practice. Ed. H. Martin Wobst and Claire Smith. London: Rout- ledge, 2003. 56–80. Print. Calloway, Colin G. First Peoples: A Documentary Sur- vey of American Indian History. Boston: Bedford– St. Martin’s, 2008. Print. Carpenter, Christopher. “Duke, EBCI Settle on Alterna- tive Site for Kituwah Substation.” Macon County News. Macon County News, 16 Dec. 2010. Web. 2 Feb. 2012. Clark, Michael P., ed. “Some Helps for the Indians.” !e Eliot Tracts. Westport: Praeger, 2003. 341–53. Print. Cohen, Matt. !e Networked Wilderness: Communicat- ing in Early New En gland. Minneapolis: U of Minne- sota P, 2010. Print. ———. “New En gland, Nonesuch.” American Literary History 22.2 (2010): 307–19. Print. Connelly, Kevin A. “"e Textual Function of Onondaga Aspect, Mood, and Tense: A Journey into Onondaga Conceptual Space.” Diss. Cornell U, 1999. Print. Cusick, David. Sketches of Ancient History of the Six Na- tions. 1825. Lockport: Niagara County Hist. Soc., 1961. Print. Dimock, Wai Chee. !rough Other Continents: American Literature across Deep Time. Princeton: Princeton UP, 2008. Print. Echo- Hawk, Roger C . “A ncient Histor y in t he New World: Integrating Oral Traditions and the Archaeo- logical Record in Deep Time.” American Antiquity 65.2 (2000): 267–90. Print. Erdrich, Louise. Books and Islands in Ojibwe Country. Washington: Natl. Geographic Soc., 2003. Print. ———. Tracks. New York: Holt, 1988. Print. Fitzgerald, Stephanie, and Hilary E. Wyss. “Land and Lit- eracy: "e Textualities of Native Studies.” American Literary History 22.2 (2010): 271–79. Print. Frothingham, Richard, Jr. !e History of Charlestown, Massachusetts. Charlestown: Emmons, 1845. Print. Harjo, Joy. In Mad Love and War. Middletown: Wesleyan UP, 1990. 19–21. Print. ———. “A Map to the Next World.” A Map to the Next World. New York: Norton, 2001. 19–21. Print. Hedge Coke, Allison. Blood Run. Cambridge: Salt, 2006. Print. Jackson, Virginia. “On Periodization and Its Discon- tents.” Introduction. On Periodization: Selected Es- says from the En glish Institute. Ed. Jackson. ACLS Humanities E- Book. Amer. Council of Learned Socs., 2010. Web. Oct. 2011. Kolosov, Jacqueline. “Poetries of Transformation: Joy Harjo and Li- Young Lee.” Studies in American Indian Literatures 15.2 (2003): 39–57. Print. Laurent, Stephen. “The Abenakis: Aborigines of Ver- mont.” Vermont History 23.4 (1955): 286–95. Print. Mann, Barbara. Iroquois Women: !e Gantowisas. New York: Lang, 2004. Print. Mann, Barbara A., and Jerry L. Fields. “A Sign in the Sky: Dating the League of the Haudenosaunee.” Ameri- can Indian Culture and Research Journal 21.2 (1997): 105–63. Print. Martin, "eodore. “"e Privilege of Contemporary Life: Periodization in the Bret Easton Ellis Decades.” Mod- ern Language Quarterly 71.2 (2010): 153–74. Print. McGann, Jerome. Radiant Textuality: Literature a"er the World Wide Web. New York: Palgrave, 2001. Print. McKie, Scott. “Tribe Opposes Substation at Kituwah Site.” Cherokee One Feather. Cherokee One Feather, 8 Feb. 2010. Web. 20 Sept. 2011. Mignolo, Walter. !e Darker Side of the Renaissance. Ann Arbor: U of Michigan P, 2003. Print. Paige, Lucius Robinson. History of Cambridge. Boston: Houghton, 1877. Print. Popol Vuh: !e Mayan Book of the Dawn of Life. Trans. Dennis Tedlock. New York: Simon, 1996. Print. Powell, Timothy B., William Weems, and Freeman Owle. “Native/ American Digital Storytelling: Situating the Cherokee Oral Tradition within American Literary History.” Literature Compass 4.1 (2007): 1–23. Print. Power, Susan. “First Fruits.” Moonwalker. Minneapolis: Milkweed, 2002. 111–37. Print. Quilter, Je#rey, et al., curators. Storied Walls: Murals of the Americas. Peabody Museum of Archaeology and Ethnology. Peabody Museum of Archaeolog y and Ethnology, 2012. Web. Oct. 2011. Reilly, F. Kent, III and James F. Garber, eds. 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Popol Vuh: !e Mayan Book of the Dawn of Life. New York: Simon, 1996. 21–62. Print. 1 2 7 . 2 ] Lisa Brooks  t h e o r ie s a n d m e t h o d o lo g ie s Townsend, Richard F., and Robert V. Sharp, eds. Hero, Hawk, and Open Hand: American Indian Art of the Ancient Midwest and South. New Haven: Yale UP, 2004. Print. Warrior, Robert. !e People and the Word: Reading Native Non"ction. Minneapolis: U of Minnesota P, 2005. Print. Wishart, David. “Period and Region.” Progress in Human Geography 28.3 (2004): 305–19. Print. Womack, Craig S. Drowning in Fire. Tucson: U of Ari- zona P, 2001. Print. ———. Red on Red: Native American Literary Separatism. Minneapolis: U of Minnesota P, 1999. Print.  The Primacy of the Present, the Primacy of Place [ P M L A t h e o r ie s a n d m e t h o d o lo g ie s work_2i5ycua2prcbpg6fqgbuyeqnwy ---- Microsoft Word - 9veverka Acta Montanistica Slovaca Ročník 16 (2011), číslo 4, 291-298 291 Mathematical Approaches to Evaluation of Old Maps Contents and Accuracy Bohuslav Veverka1, Klára Ambrožová2 and Monika Čechurová3 Old maps and stages of their development. What is it an old map? Geographical grids on old maps, drawing, measurement and accuracy. Various Prime Meridians and their history. Geographical coordinates. Modern methods of cartometric analysis. Old Czech maps. Application of Misysview, Infomapa, and MATKART software. Results of evaluation. Key words: cartometry, cartometric analysis, old maps, geographical grid, coordinate systems, Helmert’s transformation, statistical tests. Introduction The definition of an „old map” is quite problematic. The period after the Discovery of America by Christopher Columbus in 1492 is most commonly considered for a golden era of Cartography. This era was followed by an approximately 30 years’ long period of Ocean voyage discoveries of the known World, with the exception of Polar Regions and of Australia. This was an important impulse to development of Cartography. At the beginning the new information was entered into existing maps. The first drawings were only very approximate and positionally inaccurate. The maps were drawn on very expensive handmade parchment and existed only in one original. Later on these maps were engraved in copper plates and their black and white prints were colored by hand and published in tens of copies. Series of maps were assembled in atlases that belong at present to treasures of the most famous world galleries as they represent cultural heritage of humanity. There is a question until what time the maps should be designated as the old once and since when the maps are considered as new once, i.e. modern once. The authors of this contribution decided to consider for „old maps“ all cartographic products drawn up mostly by individual persons by hand on paper or engraved in metal. As long as these maps are produced in a cartographic projection (usually conic or azimuthal projections) and contain plot of geographic network or graphic length scale it is relatively easy to determine their positional accuracy. But it is necessary to point out that the positional accuracy is not constant on the entire area of the map and that it varies in different parts of the map. These variations can be represented graphically by means of quasideformation lines, i.e. lines of equal distortion of a feature investigated by cartometric method on the examined map. The era of old maps defined in the way described in this presentation ends approximately in the 18th century. Later the maps were already produced by skilled teams of state employees and experts. These maps served mainly for land taxation – cadastral maps - and for military use – topographic surveys. It is necessary to remind, that the accurate geodetic control was built up for the Cadastral Map at scale 1:2880 as well as for Military Survey at scale 1: 28 880. Both of these cartographic products are still in use. In the Czech Lands and also in Slovakia these maps were represented by so called Maps of the Stable Cadastre and by maps of the 2nd Military Survey. In Czech Lands these surveys were carried out in the period 1807-1869 based on decision of Emperor Francis I. Originals of these maps are deposited in the War Archives in Vienna. But we are not going to investigate these maps which even from present point of view are modern once, but they may be consider as a milestone between historical and modern cartography. Geographic Networks on Old Maps It is necessary to bear in mind that in the time of the creation of old maps existed practically no accurate methods for determination of geographic coordinates and there was not a common opinion on the position of the Prime Meridian as it was the time before invention of the first precision clock which has been the most important tool for determination of longitude. We do not even know if a cartographic projection was used for construction of these maps. There are almost no publications dealing with an application of Prime Meridian by ancient cartographers. This applies namely to regional maps that were mentioning a Prime Meridian only exceptionally. Without knowing the assumptions of ancient cartographers and astronomers on the position 1 prof. Ing. Bohuslav Veverka, DrSc., Czech Technical University, Faculty Of Civil Engineering, Department of Mapping and Cartography, Prague, Czech Republic,veverka@fsv.cvut.cz 2 Ing. Klára Ambrožová ,Czech Technical University, Faculty Of Civil Engineering, Department of Mapping and Cartography, Prague, Czech Republic,, klara.ambrozova@seznam.cz 3 Mgr. Monika Čechurová, Ph.D., University of West Bohemia, Faculty of Education, Department of Geography, Pilsen, Czech Republic, mcechuro@kge.zcu.cz Bohuslav Veverka, Klára Ambrožová and Monika Čechurová: Mathematical Approaches to Evaluation of Old Maps Contents and Accuracy 292 17°40´ Ferro Greenwi h λ ϕ P0 P N S normal line Z of the Prime Meridian for calculation of longitude in the eastern part of the Mediterranean it is not possible to determine the position of the Prime Meridian used for regional maps in Central Europe. This situation has been briefly described by e.g. Peter Meurer by following words: „ Special literature dealing with analysis of longitude practically does not exist“. Historical Review of Geographic Coordinates Let us briefly remind their definitions: Latitude ϕ: Angle between the normal line in point P and the plane of equator. <0, 90°> for the northern hemisphere and <0, -90°> for the southern one. Longitude λ: Angle between the plane of the local meridian and the plane of the Prime Meridian. <0°, 180°> for the eastern hemisphere and <0°, -180°> for the western one. Fig. 1. Geographic coordinates. Determination of latitude on the northern hemisphere is very simple. It is the vertical angle of the Polar Star above the horizon. This is because the Globe rotation axis intersects the skies just in the position of this star. In other words – all the stars of the northern hemisphere circulate around the Polar Star. Determination of the longitude is a much more complicated than determination of the latitude. It is because in the past there was no uniquely determined Prime (Zero) Meridian and so different countries were using different Prime Meridians. The most ancient Prime Meridian, used already in the antiquity was the Ferro Meridian. This Meridian traverses lighthouse Faro de Orchilla el Hierro which is the most western place of Europe situated on Canary Islands belonging to Spain. Difference in longitude between Ferro Meridian and Greenwich Meridian is 17º 40´. Nevertheless it is necessary to add that the value applied in the lands of former Austro-Hungarian Monarchy was more or less a convention than an accurate value, since the Cape of Orchilla lies 18º 09´ to the west from Greenwich as it is possible to find out e.g. by Google Earth. Fig. 2. Stone cross marking the position of the Ferro Prime Meridian (Wikipedia). Fig. 3. Lighthouse Faro de Orchilla (Wikipedia). Acta Montanistica Slovaca Ročník 16 (2011), číslo 4, 291-298 293 Also the French had their own Prime Meridian. Jean-Mathieu de Chazelles (1657 – 1710) determined on demand of the Science Academy in Paris longitudinal distances from the Paris Prime Meridian on several places in the region of East Mediterranean. Another French scientist De L´Isle (1675 – 1726) built cartography on a new basis. In 1724 he defined the Ferro Prime Meridian as a meridian with longitudinal distance exactly 20° to the West from the Observatory of Paris. This enabled a more realistic cartographic presentation of continents. A Prime Meridian by itself is not sufficient for longitudinal determination of observer’s position, e.g. of a ship on the Sea. It is necessary to know the time difference between the time valid at the Prime Meridian and the time at the local meridian, i.e. the position of the observer. In order to determine this difference an accurate clock is needed – a chronometer – and astronomic tables – the Star Almanac, with times of selected stars culminations at the Prime Meridian. The first known proposal of absolute time measurement comes from the famous astronomer Galileo who already in 1616 proposed a method of time measurement by movements of the moons of Jupiter. The correspondence lasted 16 long years before it was interrupted by order of the Saint Inquisition without any result (except for the home arrest for Galileo). On October 22, 1707 a great naval disaster happened at the south east coast of England near Scilly Islands. Four of five British war vessels were shipwrecked on their home night voyage after a 12 days long navigation in foggy weather by. The catastrophe caused death of many men and resulted also in announcement of a reward for invention of a method for determination of longitude. Many scientists and savants were trying to solve this problem, e.g. Galileo Galilei, Leonard Euler, Edmond Halley, Robert Hooke, etc. In 1714 the British Parliament adopted Edict on Longitude showing thus the priority in discovering a method for Longitude determination. The breakthrough had been invention of a precision clock by John Harrison in 1715 who constructed a precision marine chronometer. The weight of his first clock H1 was 250 kg and it was not very suitable instrument to use for navigation. Nevertheless his fourth model H4 from 1759 represented already a usable clock (diameter 12 cm). It is considered to be the most famous clock in the world (at least for navigation on Sea). The construction of this clock took to Harrison his entire life and the construction was completed only by his son William. The clock was tested already in 1784 when it had been known that its construction corresponds to the reward of 20 000 £ promised by the British Admiralty for solving the problem of Longitude determination. During 5 months the clock was losing merely 15 seconds. This enabled full development of Sea navigation using Sun, Moon, and 57 navigational stars for position determination. The invention of John Harrison’s (1693 – 1776) chronometer and Lunar Tables by Johann Tobias Mayers (1723 – 1762) solved the problem of Longitude determination even on Sea. Fig. 4. Chronometer – model H4 1759 (Wikipedia). The role of the Prime Meridian plays at present the Greenwich Meridian passing through the Greenwich Observatory in London. This meridian was adopted for the Prime one at a special conference (International Meridian Conference) held in October 1884 in Washington, hosting 41 delegates from 25 countries. The Conference adopted following principles: • Of a unique Prime Meridian replacing all the previous once. • The meridian passing through the passage instrument of the Greenwich Observatory should be accepted as the Prime Meridian. • All longitudes up to 180° to the East and West should be calculated starting from this Meridian. • All countries should accept the Universal Day. Bohuslav Veverka, Klára Ambrožová and Monika Čechurová: Mathematical Approaches to Evaluation of Old Maps Contents and Accuracy 294 • As the Universal Day should be accepted the Mean Solar Day starting at midnight of the Mean Solar Time in Greenwich and lasting 24 hours. • The Nautical and Astronomical Days should start everywhere by the Mean Midnight. • All technical studies regulating and contributing to adoption of decimal systems of time and space division should be promoted. The longitude of 180º represents also the calendar date. The Prime Meridian was approved by 22 against 1 vote. Haiti voted against. France and Brasilia abstained. Abstention of France was an expression of political and scientific rivalry with England. The same motive was behind the English refusal to accept the decimal system of weights and measures as they stick until now by their miles, yards, feet, and pounds. Fig. 5. The Prime Meridian - Old Royal Observatory Greenwich (Wikipedia). By solving the problem of determination of geographic coordinates and by their international standardization the cartographic nets on maps were also unified and are used in this way until nowadays. When studying positional accuracy of old maps we have to carefully investigate what Prime Meridian was used. Research of the Jean Baptist Homann’s Map of Moravia from 1726 An example of a possible cartometric research will be presented on Homann’s Map of Moravia. Outlines of the technological procedure are taken over from [1]. John Baptist Homann born in 1644 in Oberkammlach was a cartographer, geographer and publisher in Nürmberg. Among cartographers of his time he belonged to the most recognized representatives of the cartographic profession. Very important year for him was 1766 when he was appointed to Imperial Cartographer. During his life he published round 200 titles, 20 of them were taken over from Netherlands and French models. Very often he used coloring on his maps. The map shows the territory of Moravia with small overlaps to Bohemia and Silesia. The map is colored. All the settlements are represented by graphic symbols classifying the settlements according their size into: „Urbes praecipuae“, „Urbes minores“, „Oppida“, „Pagi“ and „Arces“ (in down size order). The maps show also waters, some main roads, ranges of mountains and forests. The frame of the map bears marks of latitudes and longitudes every 2‘(graphic) and latitudes every 10‘ (numeric). Geographic net is drawn in 0.5° intervals. Each „geographic field“ is delimited by two parallels and two meridians and marked on the frame by small characters. The Prime Meridian is not mentioned. In the left lower corner is drawn the scale rule. Maps are decorated in the upper and lower parts by allegoric scenes. Acta Montanistica Slovaca Ročník 16 (2011), číslo 4, 291-298 295 Fig. 6. Homann‘s map of Moravia from 1726, cutting (Source: The Map Collection of Charles University in Prague). Selection of Nodal Points Homann’s map includes geographic net with 30’ interval in latitudes as well as in longitudes. Intersections of all parallels and meridians form nodal points the coordinates of which were determined by program Misys. In all 46 nodal points were selected. Their geographic coordinates were rounded to minutes and graphical coordinates to full pixels. Graphical coordinates are coordinates of the raster in x and y axes. Origin of the system is situated in the upper right corner of the map. Selection of Settlements Names of settlements are written in German. Settlements (towns) are not drawn as built-up areas but only with circular graphic symbols. 64 settlements on the map were selected for determination of graphical and of the S-JTSK coordinates. S-JTSK coordinates were taken in Program Infomapa 14 on the spots that might have been considered as former town centers. Fig. 7. Map window showing selection of points [1]. Five suitably situated settlements were selected. Graphical coordinates were read on the old map and geographical coordinates determined in Program Infomapa 14. By comparison of these coordinates the mutual shift of these maps was estimated. These points were used for calculation of the average shift, Bohuslav Veverka, Klára Ambrožová and Monika Čechurová: Mathematical Approaches to Evaluation of Old Maps Contents and Accuracy 296 by which was used for correction of all nodal points coordinates. Corrected coordinates were used for calculation of geographic (plane) coordinates in a system that is near to the S-JTSK (System of the Uniform Trigonometric Cadastral Network), (hereafter marked as S-JTSK‘). Following points were selected: Tab. 1. Selection of points for shift determination. Point Name (old) Name (new) S – southern point Landshut Lanžhot N – northern point Altsstadt Staré Město W – western point Pilgram Pelhřimov E – eastern point Fridek Frýdek-Místek M – center Konitz Konice Their coordinates in the map of J.B. Homann: Tab. 2. Homann: Calculation of shift. bod Homann(φ) Homann(λ) Infomapa(φ) Infomapa(λ) ∆φH ∆λH S 48 ° 17 ´ 36 ° 41 ´ 48 ° 43 ´ 16 ° 58 ´ 0 ° 26 ´ -20 ° 17 ´ N 50 ° 21 ´ 36 ° 48 ´ 50 ° 9 ´ 16 ° 56 ´ 0 ° -12 ´ -20 ° 8 ´ W 49 ° 20 ´ 34 ° 11 ´ 49 ° 26 ´ 15 ° 13 ´ 0 ° 6 ´ -19 ° 2 ´ E 49 ° 26 ´ 38 ° 40 ´ 49 ° 41 ´ 18 ° 21 ´ 0 ° 15 ´ -20 ° -19 ´ M 49 ° 24 ´ 36 ° 37 ´ 49 ° 36 ´ 16 ° 53 ´ 0 ° 12 ´ -20 ° 16 ´ průměr: 0 ° 9 ´ -20 ° 5 ´ Tab. 3. Resulting shift. ∆φ ∆λ 0 ° 10 ´ -20 ° 5 ´ Helmert‘s Transformation After the calculation of Helmert’s transformation key between system of plane coordinates of nodal points in raster (outgoing system) and the S-JTSK‘ (destination system). The complete calculation was carried out in MATKART VB800 Program. Program Matkart Version VB800 by prof. Ing. Bohuslav Veverka, Dr.Sc. and Mgr. Monika Čechurová, Ph.D., has been written for calculations on old maps. The dialogue window is divi- ded into two parts that can be used independently. The upper window is for calculation of the transfor- mation key of coordinates of nodal points of the network (intersections of parallels and meridians). Lower window is for calculation of transfor- mation key for selected settlements and water bran- ching. Coordinates of the points are entered by a text file. Fig. 8. Example of a Matkart program VB800 dialogue window. Average: Acta Montanistica Slovaca Ročník 16 (2011), číslo 4, 291-298 297 The transformation key was calculated by SW VB800 using coordinates of identical points by Adjustment Method of Least Squares. The transformation coefficients are solved on condition of a minimum sum of squares of distances between the new and the original positions. As identical points are selected nodal points and points of settlements. Processing of Measured Data Due to some methodical errors in the selection of points for calculation of the shift (inaccurate registration of coordinates from the raster of Infomapa or identification of incorrect points taken for centers of settlement, etc.) some testing of transformation key sensitivity on change in shift size was carried out. The coordinates were changed by half a minute in both coordinates and in both directions. The changes were registered in a table. As it meant also mutual comparison of both maps, the shifts were changed equally. Following values of the transformation key were determined for the selected shift: Evaluation of Nodal Points The transformation key between the plane raster coordinates and the plane coordinates in the S-JTSK‘ (S-JTSK with a false origin) was calculated for a set of 800 nodal points by means of Matkart V800. Errors in the nodal points are between zero up to 6km (see point 37). There is no coherence in rise and decrease of errors in this set. Higher deviations can be due to a damage of the map at the spots of registration of graphic coordinates, non-marked intersections of parallels and meridians. Tab. 6. Homann – transformation key of nodal points. Homann č.b. Mx My M j_graf λ_graf 1 2419 -420 2455 50 ° 30 ´ 36 ° 30 ´ 2 2005 1366 2426 50 ° 30 ´ 37 ° 0 ´ 3 1675 1594 2312 50 ° 30 ´ 37 ° 30 ´ 4 778 2133 2271 50 ° 30 ´ 38 ° 0 ´ 5 1642 -621 1756 50 ° 0 ´ 36 ° 0 ´ 6 1716 -419 1766 50 ° 0 ´ 36 ° 30 ´ 7 1653 214 1667 50 ° 0 ´ 37 ° 0 ´ 8 1053 863 1362 50 ° 0 ´ 37 ° 30 ´ 9 471 1217 1305 50 ° 0 ´ 38 ° 0 ´ 10 -361 1696 1734 50 ° 0 ´ 38 ° 30 ´ 11 -935 -908 1304 49 ° 30 ´ 34 ° 30 ´ 12 -71 -607 611 49 ° 30 ´ 35 ° 0 ´ 13 530 -116 543 49 ° 30 ´ 35 ° 30 ´ 14 860 -31 861 49 ° 30 ´ 36 ° 0 ´ 15 1001 -417 1084 49 ° 30 ´ 36 ° 30 ´ 16 1127 -133 1135 49 ° 30 ´ 37 ° 0 ´ 17 646 85 652 49 ° 30 ´ 37 ° 30 ´ 18 158 230 279 49 ° 30 ´ 38 ° 0 ´ 19 -714 336 789 49 ° 30 ´ 38 ° 30 ´ 20 -1745 805 1922 49 ° 0 ´ 34 ° 0 ´ 21 -1182 707 1377 49 ° 0 ´ 34 ° 30 ´ 22 -557 535 772 49 ° 0 ´ 35 ° 0 ´ 23 99 586 594 49 ° 0 ´ 35 ° 30 ´ 24 449 526 692 49 ° 0 ´ 36 ° 0 ´ 25 713 -292 771 49 ° 0 ´ 36 ° 30 ´ 26 657 -398 768 49 ° 0 ´ 37 ° 0 ´ 27 354 -455 576 49 ° 0 ´ 37 ° 30 ´ 28 -149 -905 917 49 ° 0 ´ 38 ° 0 ´ 29 -767 -1139 1373 49 ° 0 ´ 38 ° 30 ´ 30 -3106 2967 4295 48 ° 30 ´ 34 ° 0 ´ 31 -1895 2493 3131 48 ° 30 ´ 34 ° 30 ´ 32 -1214 1880 2238 48 ° 30 ´ 35 ° 0 ´ 33 -571 1409 1521 48 ° 30 ´ 35 ° 30 ´ 34 -252 975 1007 48 ° 30 ´ 36 ° 0 ´ 35 119 -126 173 48 ° 30 ´ 36 ° 30 ´ 36 -30 -761 762 48 ° 30 ´ 37 ° 0 ´ 37 202 -5756 5760 48 ° 30 ´ 37 ° 30 ´ 38 -479 -1891 1951 48 ° 30 ´ 38 ° 0 ´ 39 -844 -2465 2606 48 ° 30 ´ 38 ° 30 ´ 40 -1370 2067 2480 48 ° 0 ´ 35 ° 30 ´ 41 -943 1349 1646 48 ° 0 ´ 36 ° 0 ´ 42 -766 2021 2162 48 ° 0 ´ 36 ° 30 ´ 43 -497 -1102 1208 48 ° 0 ´ 37 ° 0 ´ 44 -515 -1791 1863 48 ° 0 ´ 37 ° 30 ´ 45 -647 -3011 3079 48 ° 0 ´ 38 ° 0 ´ Tab. 4. Homann: values of transformation key. id ϕ λ mx [mm] my [mm] m [mm] 0 0 ° 10 ´ -20 ° 5 ´ 1101 1668 1999 The changes in the transformation key were as follows: Tab. 5. Homann – testing of the transformation key. id ϕ λ mx my m vmx [mm] vmy [mm] vm [mm] 1 -2 ° 10 ´ -22 ° 5 ´ 3021 3202 4402 -1920 -1534 -2403 2 -1 ° 40 ´ -21 ° 35 ´ 2589 2825 3831 -1488 -1157 -1832 3 -1 ° 10 ´ -21 ° 5 ´ 2160 2463 3276 -1059 -795 -1277 4 0 ° -40 ´ -20 ° 35 ´ 1739 2127 2748 -638 -459 -749 5 0 ° 40 ´ -19 ° 35 ´ 832 1498 1713 269 170 286 6 1 ° 10 ´ -19 ° 5 ´ 782 1446 1644 319 222 355 7 1 ° 40 ´ -18 ° 35 ´ 992 1528 1822 109 140 177 8 2 ° 10 ´ -18 ° 5 ´ 1351 1726 2192 -250 -58 -193 Bohuslav Veverka, Klára Ambrožová and Monika Čechurová: Mathematical Approaches to Evaluation of Old Maps Contents and Accuracy 298 Fig. 9. Homann – Comparison of RMSE by empirical tuning of an optimal shift. Conclusion The purpose of this research consisted in finding an optimal transformation key between the representations on an old map and on a modern one. Input data for the calculations are raster values of coordinates of settlements on old map and their coordinates in the S-JTSK system. Helmert’s transformation was selected because the number of identical points (settlements, branching of rivers, intersections of geographic network, etc.) is not limited. Another advantage of this transformation method is that it is a residual transformation providing us with calculation protocols with residual errors at identical points that enable us to trace an eventual error of point positioning. Results presented in [1] a [2] prove that the scale of Homann’s map varies about 1:635 000 and the accuracy of Helmert’s transformation reaches about two kilometers which was more than expected. However this high accuracy may be due to random errors in maps. It will be necessary to carry out a number of further time consuming observations and calculations for its verification. Nevertheless it is possible to declare that old maps are not only beautiful but – considering the date of their origin – also relatively very accurate from the cartographic and geodetic point of view. The Contribution has been supported by grant of the Faculty of Civil Engineering „Development of Procedures and Methods for the Research of Mathematical Elements of Old Czech Maps“ OHK1-029/12 References [1] Kratochvílová A.: Accuracy analysis of geographic network on selected old maps (In Czech: Analýza přesnosti zákresu geografické sítě na vybraných starých mapách) [Diploma thesis at the Department of Mapping and Cartography of Faculty of Civil Engineering of the Czech Technical University in Prague, under supervision of prof. Bohuslav Veverka] Prague 2009. [2] Vaněk, J: Cartometric analysis of selected historical maps of Moravia (In Czech: Kartometrická analýza vybraných historických map Moravy. [Diploma Thesis at the Department of Mapping and Cartography of Faculty of Civil Engineering of the Czech Technical University in Prague, under supervision of prof. Bohuslav Veverka] Prague 2009. [3] Veverka, B., Zimová, R.: Topographic and Thematic Cartography (In Czech: Topografická a tematická kartografie), CTU. Prague 2008. Homann - průběh změn mx, my, m 0 500 1000 1500 2000 2500 3000 3500 4000 4500 5000 0 1 2 3 4 5 6 7 8 9 id ve lik os t c hy b (m m ) m x m y m variations of mx, my, m s ca le o f e rr or s (m m ) work_2lkgyb3zrvhtlo5oorsizx5say ---- John Krigbaum | College of Liberal Arts & Sciences Skip to content University of Florida UF Directory e-Learning WebMail ONE.UF myUFL Maps College of Liberal Arts and Sciences University of Florida John Krigbaum College of Liberal Arts & Sciences Home Courses Publications Research Curriculum Vitae Related Links CLAS IT College of Liberal Arts and Sciences University of Florida John Krigbaum Professor and Undergraduate Coordinator Areas of Interest/Research Biogeochemistry Bioarchaeology Paleodiet Migration Paleoecology Paleopathology Southeast Asia New World Prehistory Old World Prehistory Paleoanthropology Primate Ecology. Contact Information Email: krigbaum@ufl.edu Phone: (352) 294-7540 Office: 1112 Turlington Hall Office Hours: Mailing address: Department of Anthropology University of Florida P.O. Box 117305 Gainesville, FL 32611-7305 Footer Menu Skip to footer content © 2021 University of Florida, Gainesville, FL 32611; (352) 392-3261. Site Updated: January 14, 2021 This page uses Google Analytics (Google Privacy Policy) work_2m2fyyozdzbmboh3lhjejs5aou ---- THE STRANDING OF NEGATION MARKERS Robert Cirillo* Abstract: The inverse scope of the negation marker in a sentence such as All the students have not read the book has frequently been described in the literature, and various explanations have been offered for why the negation marker may (but need not) take scope over the more highly positioned QP. I will argue in this paper that the best explanation for this phenomenon is the Neg Stranding Hypothesis, according to which the subject of the sentence All the students have not read the book with the [ > ] reading is the negated QP not all the students and the negation marker has been stranded by the QP all the students. Keywords: constituent negation, sentential negation, inverse scope, universal quantifier, stranding, Logical Form, reconstruction, partial deletion 1. Introduction If one quantificational element has a higher position in a syntactic structure than another quantificational element, one normally expects the higher element to take semantic scope over the lower one, particularly if a c-command relationship is present. This is reflected in the way in which Logical Form is used, as laid out in May (1985, 1989). That is, a quantifier that takes scope over another one is moved to a higher position at Logical Form. In the following sentence, one would expect the quantifier all, due to its superior position, to take scope over the negation marker: (1) All the students have not read the book. In fact, a [ > ] reading is possible in this type of sentence, with the meaning that all the students have as yet failed to read the book. The subject of this paper is the fact that in example (1) a [ > ] or inverse scope reading is also quite natural in the Germanic languages, with the meaning of the sentences in (2): (2) a. Not all the students have read the book. b. The students have not all read the book. * University of Amsterdam, Milletstraat 16-I, 1077 ZD Amsterdam, R.J.Cirillo@uva.nl. R o b e r t C i r i l l o50 I will argue that (1) is ambiguous because it has two separate syntactic analyses and that the base-structure of its [ > ] reading is actually reflected in (2a). That is, in the case of the [ > ] reading of (1), the subject is the negated quantifier phrase [QP [not [QP all [DP the students]]] and the negation marker is stranded in QP by the QP all the students. I refer to this approach as the Neg Stranding Hypothesis, which I introduce and defend in section 2 below. Sections 3 through 5 are devoted to a presentation and rejection of other syntactic approaches to the [ > ] reading of (1), and section 6 contains a brief summary and final comments. 2. Neg Stranding For the sake of clarity I will begin with the reading of (1) in which there is no inverse scope, that is, the reading in which scope reflects Surface Structure word order. Following Zeijlstra (2004) and Cirillo (2009), I assume that the [ > ] reading of (1) is a classic instance of sentential negation and is derived from the following base-structure: (3) PerfP 2 SPEC Perf ́ not 2 Perf vP have 2 SPEC v ́ QP 6 6 read the book all the students The auxiliary verb have will move to I/AgrS/T and the subject QP all the students will move to SPEC of IP/AgrSP/TP. Regarding the [ > ] or inverse scope reading of (1), I propose that it stems from the fact that no sentential negation is involved and that the negation marker and the subject QP form a constituent, a negated QP, at some point in the derivation. The base-structure will look like (3) except that the negation marker, instead of originating in [SPEC, PerfP], will be base-generated in [SPEC, QP]: The stranding of negation markers 51 (4) PerfP 2 SPEC Perf ́ 2 Perf vP have 2 SPEC v ́ QP 6 2 read the book SPEC QP not 2 SPEC Q´ 2 Q DP all 6 the students Under this approach, the upper QP node can move to [SPEC, AgrSP], producing (2a), or the lower QP node can move to [SPEC, AgrSP], stranding the negation marker and producing the word order in (1) but the meaning of (2a and 2b). It is also possible, following the standard stranding analysis of floating quantifiers as presented in Sportiche (1988), Giusti (1990), Shlonsky (1991) and Cirillo (2009), for the DP the students to move out of QP and strand both the negation marker and the universal quantifier in QP, producing (2b). After the negation marker has been stranded, the question arises as to how the pre-stranding scopal relations are preserved, since the quantifier has moved above negation and could conceivably produce a [ > ] reading. Note that this would be equivalent to the sentential negation reading produced by a true sentential negation structure like the one in (3), in which the negation marker originates in the SPEC position of the verbal phrase that it is negating. It is actually not difficult to explain the lack of a sentential negation reading in (4) after Neg Stranding. After all, in the derivation of the [ > ] reading of (1), as can be seen in (4), the stranded negation marker does not c-command PerfP at any point in the derivation and should not be able to take scope over it. Negation only c-commands the trace of the moved QP.1 1 One could perhaps still ask why the derivation in (4) with Neg Stranding does not produce a [ > ] reading, since the quantifier has moved above negation and could be said to dominate it. This will not be discussed here because of space restrictions. The interested reader is referred to Cirillo (2009: 104-114). R o b e r t C i r i l l o52 From a technical standpoint, the Neg Stranding model works, producing the desired output. It also captures a significant generalization by deriving three sentences with the same words and meaning, namely (1) with the [ > ] reading, (2a) and (2b), from a common base-structure. Furthermore, there is independent support for a stranding approach, given the evidence that can be found for preposition and quantifier stranding. The question is whether there is any compelling evidence for Neg Stranding. Compelling evidence would be any instance in which a negation marker is not a sentential negation marker and is separated from the constituent that it negates. I will now present such evidence, beginning with German sentences in which sentential and constituent negation co- occur. Imagine a situation in which a student was expected to read a series of books. Teacher A asks in (5a) which books the student has not read. Teacher B, rather disappointed in the student, responds in (5b), with emphasis on the word all, that the student has not read any of the books. Teacher C, who happens to know that the student has read one of the books, contradicts Teacher B by saying that it is not true for all the books that the student has not done the required reading. (5) a. Welche Bücher hat er nicht gelesen? which books has he not read b. All die Bücher hat er nicht gelesen! all the books has he not read c. Nicht all die Bücher hat er nicht gelesen! not all the books has he not read It is possible, if not terribly elegant, to strand the constituent negation marker in (5c) and retain the same meaning: (6) All die Bücher hat er nicht nicht gelesen! all the books has he not not read It could not be the case that both the negation markers in (6) are sentential. If they were, in a Germanic language they would cancel each other out and the meaning of the sentence would be that the student had read all the books. The first negation marker can only be a stranded constituent negation marker. It negates the topicalized object DP all die Bücher. Let’s now look at some other examples in which there is co-occurrence of sentential and constituent negation markers, since this type of example is perhaps the best evidence in favor of Neg Stranding. Observe the following three sentences in Dutch, German and English, respectively: The stranding of negation markers 53 (7) a. Al de studenten zijn niet niet gekomen. all the students are not not come b. All die Studenten sind nicht nicht gekommen. all the students are not not come c. All the students have not not come. All these sentences are ambiguous for a reading in which the negation markers are both sentential and cancel each other out, with the meaning that all the students have come, and a reading in which the first negation marker takes scope over the subject QP, with the meaning that not all the students have not come. This is strong evidence in support of Neg Stranding. Another example of compelling evidence for Neg Stranding can be found in contrastive not...but constructions, which involve constituent negation: (8) He fed not the dog but the cat. The negation marker cannot be a sentential negation marker here, for three reasons. It is not in the position of sentential negation, there is no do-support, and not...but constructions are used only in the case of contrastive constituent negation. Let’s now take the same sentence in German: (9) Er hat nicht den Hund gefüttert, sondern die Katze. he has not the dog fed but the cat Now let’s take this sentence and pre-pose the negated constituent: (10) Nicht den Hund hat er gefüttert, sondern die Katze. not the dog has he fed but the cat This is clearly a case of constituent negation, since the negation marker has been pre-posed along with the rest of the constituent. And, example (10) can undergo Neg Stranding, as shown in (11), in which the negation marker remains a constituent negation marker that has scope over the pre-posed object: (11) Den Hund hat er nicht gefüttert, sondern die Katze. the dog has he not fed but the cat Inverse scope without sentential negation can only mean one thing: the stranding of a constituent negation marker. As mentioned above, additional support for the Neg Stranding Hypothesis comes from its ability to capture a significant generalization. Consider the R o b e r t C i r i l l o54 following three sentences, which contain exactly the same words and mean exactly the same thing: (12) a. Not all the students have read the book. b. The students have not all read the book. c. All the students have not read the book. (I.e., the [ > ] reading.) The first two of these sentences cannot be produced without the following structure: (13) QP 2 SPEC QP not 2 SPEC Q ́ 2 Q DP all the students Example (12a) could not be produced without (13) because we would otherwise not get the negation marker into sentence-initial position. Example (12b) could also not be produced without the constituent negation marker in (13) because a sentential negation marker would be in the wrong place. This becomes evident if a sentential negation marker is inserted into (12b): (14) The students have not all not read the book. If (12a) and (12b) are derived from the structure in (13), a major generalization would be missed if (12c) were not also derived from the same structure. The Neg Stranding Hypothesis captures this generalization. For further discussion of evidence in support of Neg Stranding the reader is referred to Cirillo (2009).2 The conclusion that I draw in this section is that Neg Stranding is an indispensable part of a theory of syntax, and since we “get it for free”, so to speak, it should at least be considered as a possible explanation for the inverse scope observed in (1). Of course, the fact that it is the most inexpensive explanation does not mean that it is the correct one. In Sections 3-5 we will therefore examine some alternative approaches.3 2 Cirillo (2009: 104-108, 115-118 and 149-150). 3 I first developed the Neg Stranding Hypothesis in 2005. Three years later I heard about an article by Höhle, written in 1991, in which it is suggested that inverse scope can arise when a negation The stranding of negation markers 55 3. Covert movement of negation Whenever there is ambiguity such as that observed in (1), the first thing that comes to mind is that the explanation might be found in covert movement or Logical Form. Under this type of approach, the negation marker in (1) would be covertly moved from its position as sentential negation marker to sentence-initial position, probably [SPEC, QP], which would produce the LF illustrated in (2). The question that immediately arises here is whether we want to allow the covert movement of negation. Consider the following examples from Italian: (15) a. Tutti gli studenti non l’hanno letto. [ > ] all the students not it have read b. Non tutti gli studenti l’hanno letto. [ > ] not all the students it have read Most Italian speakers find (15a) to be an unnatural sounding sentence, but it is not generally rejected as ungrammatical. Some speakers report that they can get a [ > ] reading in (15a), but for most speakers only the [ > ] (Surface Structure) reading is available. Romanian and Portuguese speakers seem to universally reject the sentence. There will be more on Romanian and Portuguese in Section 7. The point that I want to make here is that the [ > ] reading is either difficult or impossible in the Romance languages. If the covert movement of negation were an option, it would be possible to move the negation marker in (15a) to sentence-initial position, thereby producing the LF represented in (15b) and the corresponding reading. Since the [ > ] reading is difficult or impossible in the Romance languages, covert movement of negation does not seem to be an option.4 Consider now the following German sentence from Höhle (1991): (16) Alle Politiker hat so mancher nicht verstanden. all politicians has many a person not understood ‘Many people did not understand all the politicians.’ marker c-commands the trace of a moved quantifier. This is not exactly the same as Neg Stranding, but the similarity between Höhle’s approach and mine is striking and has to be mentioned. Christopher Columbus had never heard of Leif Ericson, but Ericson found America first. 4 Space restrictions do not permit a discussion of why the Romance languages tend not to allow inverse scope in sentences like (15a). It has to do with the idea, following Zeijlstra (2004) and Cirillo (2009), that negation markers in the Romance languages are highly positioned syntactic heads, dominating all verbal phrases, while in the Germanic languages they are maximal projections that can occupy the SPEC position of both verbal and nominal phrases. For a detailed discussion see Cirillo (2009: 128-147). R o b e r t C i r i l l o56 In this sentence the direct object Alle Politiker (all politicians) has been topicalized. The word Alle (all) has rising intonation and nicht (not) has falling intonation and primary stress. The meaning of the sentence is that there are several people who did not understand all the politicians. Scopal relations are thus [ >  > ]. The question is whether the [ > ] reading could have been obtained by moving negation at LF. Höhle argues against this option by pointing out that moving the negation marker to the position in front of the universal quantifier does more than just create a [ > ] reading. It changes a [ >  > ] reading to a [ >  > ] reading. Thus, the covert movement of negation does much more than it is supposed to do, and is probably not the right solution. Höhle is suggesting that scope, at least in the case of negation, is determined hierarchically and not via covert movement. The claim that scope is determined hierarchically is consistent with what is presented in Kayne (1998). Because of the evidence presented in (15) and (16), it is hereby concluded that covert movement of negation is not an option in resolving the ambiguity of (1). 4. Reconstruction If the covert movement of negation is not available for arriving at the [ > ] reading in (1), one should perhaps consider another form of covert movement, namely, reconstruction. Following the copy theory of movement in Chomsky (1995), reconstruction is simply the interpretation of a lower copy. The base-structure copy of all the students in (1) is presumed to be inside vP and below the negation marker. Interpretation of this lower copy would thus produce the [ > ] reading. Note that this would be an instance of reconstruction under A-movement. There is widespread agreement in the literature on the need for reconstruction under A-bar movement, but reconstruction under A-movement is controversial. Some, such as Lasnik (1998), have argued that it does not occur at all. The vast majority of the references to reconstruction under A-movement in the literature are made in connection with anaphora that precede their binding antecedents in the Surface Structure. The following is a quote from Barss (2001: 686): In general, we will observe reconstruction effects under A-movement only in cases where there is an argument NP (the potential antecedent) which c- commands the deep position but not the surface position of the raised NP which contains an anaphor. Due to space constraints, I will not dispute in this paper the need for reconstruction under A-movement in the case of anaphora, however I will The stranding of negation markers 57 mention that in Cirillo (2009: 109-111), while discussing Belletti and Rizzi (1988), I attempt to cast some doubt on the ability of reconstruction to resolve all the problems related to anaphora. Here I want to concentrate on the usefulness of reconstruction in resolving ambiguity. I begin with the following sentence, from Fox (1999): (17) [Someone from New York]1 is very likely t1 to win the lottery. According to Fox’s analysis, if no reconstruction takes place in this sentence, the quantifier someone takes scope over the raising verb to be likely and the meaning is that a specific person in New York who has presumably bought a lot of lottery tickets is probably going to win the lottery. If reconstruction does take place, the raising verb to be likely takes scope over someone and the meaning is that it is probable that a non-specific person from New York will win the lottery, perhaps because more lottery tickets were sold in New York than in any other city. The question is whether this analysis could be used to explain the type of ambiguity observed in (1). There are a number of reasons why I question the appropriateness of applying Fox’s analysis of (17) to a sentence such as (1). I will ignore the fact that nearly all of Fox’s examples involve raising verbs and that none of them involve negation or the quantifier all, which already casts doubt on the applicability of Fox’s analysis to (1). There are other reasons for not adopting Fox’s analysis for sentences like (1). First of all, under an approach like Fox’s, reconstruction is basically an optional LF operation that undoes the effects of raising. But raising is also optional at the Surface Structure. Both of the following sentences are possible: (18) a. Someone from New York is very likely to win the lottery. b. It is very likely that someone from New York will win the lottery. If an operation is not obligatory, it does not seem very economical to optionally raise an element at the Surface Structure and then optionally lower it again at LF. This is one problem with Fox’s analysis. An even bigger problem is the fact that quantifier lowering or reconstruction in (17) does not disambiguate at the Surface Structure. The two sentences in (18), which are based on (17) with and without raising, are both ambiguous. If reconstruction does not disambiguate at the Surface Structure it is not clear how it would be any more effective at LF. This should cast considerable doubt on whether reconstruction at LF is really the way to disambiguate a sentence, whether it be one of the sentences in (18) or example (1). The cause of the ambiguity of the sentences in (18) has nothing to do with syntactic structure but with the specificity or non-specificity of the quantifier someone. R o b e r t C i r i l l o58 Moving away from Fox’s analysis, I would like to present some additional evidence that A-movement reconstruction is of questionable use in matters of ambiguity. Consider the following ambiguous sentence: (19) Everybody loves someone. Under the reading in which everybody takes scope over someone, quantifier raising is unnecessary, since everybody outscopes someone by virtue of its higher position. If the quantifier everybody is raised at LF even though raising is unnecessary, reconstruction is also unnecessary and is therefore irrelevant with or without quantifier raising. Consider the reading of (19) in which someone takes scope over everybody. In order to get this reading, someone has to undergo quantifier raising at LF. Reconstruction in this instance would undo the effect of quantifier raising and produce an undesired reading. In other words, regardless of how one interprets (19), reconstruction is inappropriate and not a suitable way to resolve ambiguity. The following example from Sportiche (2005: 34) illustrates that there are situations in which reconstruction creates ambiguity rather than resolving it: (20) Everyone seems not to be listening. This sentence has only a [ > ] reading. A reconstructed version of this sentence, without raising, is ambiguous for a [ > ] and a [ > ] reading: (21) It seems that everyone is not listening. One last problem that I must point out with A-movement reconstruction is that it is not permitted in the Romance languages when negation is involved. The following Italian sentence, comparable to (15a), allows only a [ > ] reading for most speakers: (22) Tutti gli studenti non hanno letto il libro. all the students not have read the book I assume that the base-position of the subject QP tutti gli studenti is in [SPEC, vP], below negation. If reconstruction (interpretation of the lower copy of the subject QP) were possible in this sentence, a [ > ] would be possible, but such a reading is unavailable or difficult in the Romance languages. To summarize this section, A-movement reconstruction is not a convincing means of disambiguating. It poses economy issues, it sometimes fails to resolve The stranding of negation markers 59 ambiguity, it sometimes creates ambiguity, and it is sometimes not permitted at all. It is no surprise that it is not universally accepted. 5. Partial Deletion à la Nuñes Another potential explanation for the ambiguity in (1) is partial deletion in the manner of Nuñes (2004). Nuñes’ approach is based on the copy theory of movement. Theoretically, in a sentence like (1) optional partial deletion could have taken place as follows: (23) [IP[QP Not all the students] [PerfP have [vP [QP not all the students] read the book]]] Nuñes argues that this type of deletion (called chain reduction) is needed for two reasons. First of all, normally only one copy in a chain can be pronounced. Secondly, in keeping with the Linearization Correspondence Axiom (LCA) in Kayne (1994), copies are non-distinct. Consequently, if there is more than one copy of an item, it is unclear which copy should be linearized with the other elements in a clause. Without deletion, linearization cannot take place and the derivation will crash. Nuñes points out that partial deletion needs to be constrained in order to prevent it from generating absurd sentences. Consider the following sentence from Nuñes (2004): (24) The tall man appears to have been kissed. In the derivation of (24) there are three copies of the subject forming a chain: (25) [The tall man] appears [the tall man] to have been kissed [the tall man]. In order to derive the desired version of this sentence, two deletion operations are needed, as follows: (26) [The tall man] appears [the tall man] to have been kissed [the tall man]. Using partial deletion, one could easily generate the following absurd sentence: (27) *The appears tall to have been kissed man. This sentence would be derived by deleting as follows: R o b e r t C i r i l l o60 (28) [The tall man] appears [the tall man] to have been kissed [the tall man]. Nuñes refers to this as “scattered deletion”. He blocks this type of output by appealing to principles of Economy. In the correct version of this sentence, as I just mentioned, there are only two deletion operations. In this nonsensical product of scattered deletion, there are at least four deletion operations. Thus, only the correct version will be generated by the system because Economy will block other outputs. The problem is that a partial deletion approach is unable to generate the [ > ] reading of a sentence like (1). Remember that in the base structure of this sentence the subject is the negated QP not all the students. If we do not strand the negation marker, we have just one deletion operation in the derivation, as follows: (29) [Not all the students] have [not all the students] read the book. If we want to produce (1) with a [ > ] reading, not one but two deletion operations are needed, as follows: (30) [Not all the students] have [not all the students] read the book. Nuñes’ prediction is therefore that this version of the sentence will never be generated because it involves more deletion operations than (29). This false prediction of the partial deletion approach affects not only Neg Stranding. It affects all kinds of stranding, including quantifier stranding and even preposition stranding. For this reason, Nuñes’ partial deletion approach is not a viable alternative to Neg Stranding (or any other type of stranding analysis.) 6. Conclusions I believe that I have provided strong evidence that the stranding of negation markers occurs in natural language. I have also proposed that since a syntactic theory needs to include the stranding of negation markers anyway, the Neg Stranding Hypothesis might be a good way to account for the inverse scope of negation in sentences like (1). In any case, Neg Stranding seems to be less problematic than other syntactic approaches such as movement of negation at LF, reconstruction, or partial deletion. It may come as a surprise that I would like to end this article by making a proposal for future research that would investigate a semantic explanation for the inverse scope of negation. In Section 3 I pointed out that the Italian sentence in (15a), which is comparable to the English sentence in The stranding of negation markers 61 (1), is judged to be unnatural by most Italian speakers and ungrammatical by virtually all Portuguese and Romanian speakers. The question is why this is so. I would like to suggest that there is a hierarchy of quantification and that negation is the strongest form of quantification, outranking even universal quantifiers. If a universal quantifier precedes negation, the natural reaction is that the quantifier, by virtue of its higher position, should be taking scope over negation, but this produces an unnatural feeling because scope, as reflected in word order, is incompatible with the relative quantificational strength of the quantifiers involved. The suggestion is that a universal quantifier should simply not take scope over negation, the stronger quantifier. This could very well be why speakers of Romance languages do not like sentences in which a universal quantifier precedes negation and thus appears to take scope over it. Even in the Germanic languages, many speakers report that the most natural interpretation of sentences like (1) with neutral intonation is the one in which negation takes scope over the universal quantifier, contra word order. All this points to the idea of a hierarchy of quantification. Büring (1997) does not discuss a hierarchy specifically, but he does point out that there are situations in which it is unnatural for negation to be out-scoped by another quantifier, regardless of word order. In Zeijlstra (2004) mention is made of a constraint that seems to exist against moving a universal quantifier above negation at LF. All this does seem to point to a kind of quantificational hierarchy. Gualmini and Moscati (2009) show interesting evidence that in Italian child language negation can have inverse scope over modal verbs that is not allowed in adult speech, again pointing to the strength of negation with regard to other forms of scope-taking elements. Additional support for the idea of a quantificational hierarchy can be found in the following sentences: (31) a. Everybody loves someone. [ > ] or [ > ] b. Someone loves everyone. [ > ] or [ > ] Both of these sentences allow two readings. That the [ > ] reading would be more natural than the [ > ] reading in (31a) is perfectly understandable, given the word order of the sentence. However, the [ > ] interpretation is more natural than the [ > ] interpretation in (31b) as well, in spite of the [ > ] order. This could also have to do with the relative strength of  with respect to . Thus, in spite of the success of the Neg Stranding Hypothesis in explaining inverse scope in purely syntactic terms, I believe that it would be worthwhile to investigate whether there is a syntax-semantics interface that dictates that when two quantifiers co-occur, regardless of syntactic structure, the stronger form of quantification, negation, will take precedence. Such an investigation would ideally involve a large number of different language families. R o b e r t C i r i l l o62 References Barss, A. 2001. Syntactic reconstruction effects. In M. Baltin and C. Collins (eds.), The Handbook of Contemporary Syntactic Theory, 670-696. Oxford: Blackwell. Belletti, A. and Rizzi, L. 1988. Psych verbs and Theta Theory. Natural Language and Linguistic Theory 6: 293-352. Büring, D. 1997. The great scope inversion conspiracy. Linguistics and Philosophy 20: 175-194. Chomsky, N. 1995. The Minimalist Program. Cambridge, MA: MIT Press. Cirillo, R. 2009. The Syntax of Floating Quantifiers: Stranding Revisited. PhD dissertation, Landelijke Onderzoekschool Taalwetenschap, Utrecht. Fox, D. 1999. Reconstruction, Binding Theory, and the interpretation of chains. Linguistic Inquiry 30: 157-196. Giusti, G. 1990. Floating quantifiers, scrambling and configurationality. Linguistic Inquiry 21: 633-641. Gualmini, A. and Moscati, V. 2009. The early steps of modal and negation interactions: Evidence from child Italian. In E. O. Aboh, E. van der Linden, J. Quer and P. Sleeman (eds.), Romance Languages and Linguistic Theory: Selected Papers from ‘Going Romance’ Amsterdam, 2007, 131-144. Amsterdam/Philadelphia: John Benjamins. Höhle, T. 1991. On reconstruction and coordination. In H. Haider and K. Netter (eds.), Representation and Derivation in the Theory of Grammar 138-197. Dordrecht: Kluwer. Kayne, R. 1998. Overt vs. covert movement. Syntax 1: 128-191. Kayne, R. 1994. The Antisymmetry of Syntax. Cambridge, MA: MIT Press. Lasnik, H. 1998. Some reconstruction riddles. University of Pennsylvania Working Papers in Linguistics 5 (1): 83-98. May, R. 1989. Interpreting Logical Form Linguistics and Philosophy 12: 387- 435. May, R. 1985. Logical Form: Its Structure and Derivation. Cambridge, MA: MIT Press. Nuñes, J. 2004. Linearization of Chains and Sideward Movement. Cambridge, MA: MIT Press. Shlonsky, U. 1991. Quantifiers as functional heads: A study of quantifier float in Hebrew. Lingua 84: 159-180. Sportiche, D. 2005. Division of labor between merge and move: Strict locality of selection and apparent reconstruction paradoxes. . Sportiche, D. 1988. A theory of floating quantifiers and its corollaries for constituent structure. Linguistic Inquiry 19: 425-449. Zeijlstra, H. 2004. Sentential Negation and Negative Concord. PhD dissertation, Landelijke Onderzoekschool Taalwetenschap, Utrecht. work_2rg3hmhjr5g3xcaf4ytizvp2ee ---- 152 book reviews © supriya m. nair, 2015 | doi: 10.1163/22134360-08901025 This is an open access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported (cc-by-nc 3.0) License. Rudyard J. Alcocer Time Travel in the Latin American and Caribbean Imagination: Re-reading History. New York: Palgrave Macmillan, 2011. xv + 238 pp. (Cloth us$85.00) If the preoccupation with history—or the absence thereof—is inescapable in LatinAmericanandCaribbeanliterature,a fixationwithtemporalitycanseem justas inevitable.TimeTravel intheLatinAmericanandCaribbeanImagination examines the links between fictional time travel and the history of Hispanic conquest, slavery, and servitude in the Americas, with particular attention to the regions mentioned in the title as against the British colonization of the northern part of the continent. The prologue, which begins with epigraphs invoking the cyclical nature of time, is fittingly titled “Time Out of Joint,” sug- gesting that temporal dislocations from the past will haunt the present and future of this hemisphere. Rudyard Alcocer argues that the primary rupture of the Conquest (and the Middle Passage for African diasporic communities) creates a wound so deep that a substantial corpus of time travel has emerged in literature and popular culture to reconsider, and perhaps overcome, the enduring legacies of those traumas. The question is whether narratives of time travel serve as “escapism” or as “surgical intervention” (p. xiv), and Alcocer’s critical readings of these narratives seem to find both possibilities. One of the book’s strengths is its nuanced perspective of the contemporary compar- ative literatureonthetheme, inflectedbymultipletheoreticalanddisciplinary approaches (psychoanalytic, postcolonial, deconstructive, historical, anthro- pological, cultural studies). The book has four main chapters. The first includes an analysis of a number of texts, including North American fiction (e.g., S.M. Stirling’s Conquistador: A Novel of Alternate History and Orson Scott Card’s Pastwatch: The Redemption of Christopher Columbus) and Mexican film and fiction (e.g., Gustavo Loza’s Al otro lado [To the Other Side], Homero Aridjis’s La leyenda de los soles [The Leg- endoftheSuns]),andafewofCarlosFuentes’sshortstories.Thesecondchapter focusesonTrinidadianauthorKevinBaldeosingh’smassiveAnglophonenovel, The Ten Incarnations of Adam Avatar, and Cuban writer Daína Chaviano’s El hombre, la hembra y el hambre [Man, Woman, and Hunger]. The third revis- its the myth of La Malinche in the Mexican writer Marcela del Río’s play El sueñodeLaMalinche[TheDreamofLaMalinche]andNicaraguanauthorGio- condaBelli’s firstnovel, Lamujerhabitada[TheInhabitedWoman].Thefourth chapter moves to popular culture versions of time travel in films, children’s stories, gaming, and pedagogical sources (language learning) that cement the variousstereotypesofthe“conquered”peoples: theMayansandtheIncastime- lessly frozeninalostworld,pronetosavageviolence,orannihilatedbycultural Downloaded from Brill.com04/06/2021 01:09:24AM via free access http://creativecommons.org/licenses/by-nc/3.0/ http://creativecommons.org/licenses/by-nc/3.0/ book reviews 153 New West Indian Guide 89 (2015) 89–230 apocalypse and superior invaders. Alcocer claims that popular culture largely repeats colonial discourse of the archives, historiography, and high culture in locating modernity and advanced civilization in the era of European coloniza- tion and settlement. The afterword, which discusses how heritage tourism in Puerto Rico dis- turbingly combines a reification of Taíno culture with a corresponding elision of African elements, demonstrates the continuing obsession with the rein- vented past, here romanticized by ethnocentric and consumerist nostalgia. Although multiple titles mentioned in passing can occasionally be bewilder- ing, the book’s impressive range makes a compelling case for its significance. Despite the varied terrain, the lucid prose, helpful translations, and clear tran- sitionsfromonechaptertothenexthelpreadersnavigatethebookwithouttoo much confusion. While the book does not engage time from a philosophical angle as Wilson Harris does in his notion of “infinite rehearsal,” it considers various classifica- tionsof time. “Inotherwords,whatmodernreadersandwritersare inclinedto categorizeundersciencefictionor fantasy(i.e., contactbetweendifferenttime periods) may in fact have held similarities to certain pre-Columbian under- standingsofhowtimeworks…Fictional, interventionistvisitstothepast…can alsohavepracticalobjectivesinthepresent,”Alcocerconcludes(p.158).Writers like Alejo Carpentier who flout conventional notions of clock-and-calendrical timemayin factbelieve inthecoexistenceof temporalcategories thatareusu- ally considered distinct from each other, pointing to nonlinear routes of time travel. One therefore doesn’t travel back to the past when it is believed that thepastalreadyinhabitsthepresent.Occasionally, timecanmovebackwardor standstillas intheproblematicrepresentationofastagnantpostrevolutionary Cuba, which Alcocer does not critique as much as he does the mythification of indigenous peoples or the idealization of origins in African diasporic returns tothe“homeland.”Conversely, revisionistnarrativescanactuallyreify theview of the past as a fated curse, a pessimistic notion that engages in a “negative determinism,” inflexibly tying the problems in the present to a blighted past (p. 34). The uncanny re-turns to the past imply unresolved issues that demand repeatedvisits tomomentsofcrisis.Sometimesthesevisitscongeal thepast,at others they rewrite it and critique the dysfunctional present, and at still others they gesture toward a hopeful future once these fictional “interventions” con- front traumas. Alcocer situates time travel in these regions by emphasizing continuous historical trauma, but he does not then account for other contexts of time travel narratives that do not share this history as, for example, in Western fiction. Although it is unclear how these non-Western fictional “interventions” Downloaded from Brill.com04/06/2021 01:09:24AM via free access 154 book reviews New West Indian Guide 89 (2015) 89–230 materially alter the present, the book makes an important contribution to the scholarship of time travel by including Latin America and the Caribbean. Supriya M. Nair Department of English, Tulane University, New Orleans la 70118, u.s.a. supriya@tulane.edu Downloaded from Brill.com04/06/2021 01:09:24AM via free access mailto:supriya@tulane.edu work_2sdcrn4hpjhblonzhtcra3trum ---- wp-p1m-38.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-38.ebi.ac.uk no 218197357 Params is empty 218197357 exception Params is empty 2021/04/06-02:09:22 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. 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Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_2t2wlwelvja2hkajtpmhpcdo7m ---- S2398772317000666jra 267..271 SYMPOSIUM ON GLOBAL ANIMAL LAW (PART I) ANIMAL COLONIALISM: THE CASE OF MILK Mathilde Cohen* Greta Gaard writes that “[t]he pervasive availability of cows’ milk today—from grocery stores to gas stations— is a historically unprecedented product of industrialization, urbanization, culture, and economics.”1 To these fac- tors, I would add colonialism and international law; the latter understood broadly to include the rules considered binding between states and nations, transnational law, legal transplants, international food aid, and international trade law. Until the end of the Nineteenth Century, the majority of the world population neither raised animals for their milk nor consumed animal milk. Humans are unique in the mammalian realm in that they drink the milk of other species, including beyond infancy. With the European conquest of the New World and other territories start- ing in the Sixteenth Century, dairying began to spread worldwide—settlers did not set out to colonize lands and people alone; they brought with them their flora, fauna, and other forms of life, including lactating animals such as cows and sheep. Though limited to a narrow group of animals and products, the story of milk’s globalization may have broader implications for how we understand the genealogy of global animal law. It suggests that animal law may long have been “global,” at least since the modern era, which saw the colonization of lands in the Americas, Africa, Asia, and Oceania by a few European countries and the accompanying migration of ideas concerning the legal status of animals. There is a fundamental difference between the new and the old global animal law, however. While the contemporary global animal law initiative embraced by this symposium is an emancipatory movement aiming at promoting animal welfare, the old, colonial animal law was only global for imperialist ends, displaying little concern for the well-being of animals, colonized people, and ecosystems. Bridging the gap between scholarship on animal colonialism and on imperialism and motherhood, this essay argues that lactating animals became integral parts of colonial and neocolonial projects as tools of agroexpansion- ism and human population planning. Due to its disruptive effects on breastfeeding cultures, the global spread of dairying has not only been detrimental for the welfare of animals, but also for humans’, especially mothers and their children. I recognize the simplistic aspect of grouping and analyzing together disparate epochs, regions, peo- ples, and animals in an interimperial historical vein. I do not mean to imply that these epochs, regions, peoples, and animals belong to a coherent whole, but only that despite their diversity, they have experienced comparable forms of state-building projects centered upon the consumption of animal milk. As an aside, animal protection law and advocacy is often critiqued for its supposed cultural imperialism, but as the following discussion illustrates, it may be that the lack of concern for animal welfare exhibited by legal systems was bequeathed by hegemonic European colonizers. * Professor of Law, University of Conneticut. For helpful conversations and comments on earlier drafts, I thank Erin Delaney, Amy DiBona, and Elizabeth Emens. 1 Greta Gaard, Toward a Feminist Postcolonial Milk Studies, 65 AM. Q. 595, 597 (2013). doi:10.1017/aju.2017.66 The American Society of International Law and Mathilde Cohen © 2017. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. 267 http://www.bbk.ac.uk/bih/lcts/summer-school-2015/esther-leslie/65.3.gaard.pdf http://www.bbk.ac.uk/bih/lcts/summer-school-2015/esther-leslie/65.3.gaard.pdf In what follows, after presenting the notion of animal colonialism, I focus on two of its components, which I call “milk colonialism” and “breastfeeding colonialism” before concluding with a provocative proposal about the international right to breastfeed. Animal Colonialism Animal colonialism can be defined as a dual phenomenon, consisting, on the one hand, in using animals to colonize lands, native animals, and people and, on the other hand, in imposing foreign legal norms and practices of human-animal relations upon communities and their environments. Beginning with the work of Alfred Crosby on ecological imperialism—in particular his insight that the conquest of the New World was as much a biological one as a political one2—studies have accorded domesticated farm animals an instrumental role in the establish- ment of colonies around the globe. Virginia DeJohn Anderson writes: “all Europeans … enlisted livestock as part- ners in colonization.”3 By displacing local fauna, altering native weeds, seeds, grasses, and cultivars, ranching and dairying altered New World ecosystems to advance European purposes. This biological invasion disrupted the lives of native peoples, animals, and their environments. Across time and space, colonists used animals to conquer ecosystems and their inhabitants, from Christopher Columbus who transported horses, cattle, swine, sheep, and goats to Caribbean islands to French settlers who brought cattle to New France starting in 1617, to Dutch settlers who exported their first cows to New York in 1629, to the British who landed with their sheep and bovines on the shores of Australia and New Zealand in the Eighteenth and Nineteenth Centuries. Similar in these disparate endeavors was the idea that the importation of European animals and the destruction of local fauna, flora, and local foodways were justified by the goal of “improving” agriculture and population health. Animals and their “products”—in particular milk, leather, fur, bone, wool, and silk—were and remain constitutive of national identity and imperial power. They operate as tools of domination to control territories, humans, animals, and ecosystems. Animal colonialism also served as a pretext for conquest itself: as the imported cattle multiplied, more grazing land was needed, justifying further expansions. Animal colonialism involves not only the migration of animals, but also of the legal status they were accorded in the Old World. Imperial states can recognize or refuse to recognize the legitimacy of multispecies relationships in the regions they conquer, attempting to regulate them or replace them with new ones. In both the civil law and the common law traditions, animals were the personal property or chattel of their human owners and could not pos- sess rights.4 They were means to human ends. One illustration of how the property status of animals became “globalized” is the Seventeenth-Century introduction of the crime of animal theft in the Chesapeake and present day Virginia. While Northern native peoples such as Algonquians did not claim any form of property over animals —and had domesticated very few—Virginia’s governor Francis Wyatt proclaimed in 1623 that anyone convicted of stealing any “Beast or Bird of Domesticall or tame nature” worth more than twelve pence would be put to death.5 By then colonists’ cattle and other domesticated animals were often left to run wild due to the lack of fenced pasture and manpower. These loose animals became a source of recurrent litigation either because they spoiled farmers’ crops or were “stolen.” Preserving the status of animals as property was a way to reinforce the authority of the English rule as wild livestock were considered as property of the Crown. 2 ALFRED CROSBY, ECOLOGICAL IMPERIALISM: THE BIOLOGICAL EXPANSION OF EUROPE 900–1900 (1986). 3 VIRGINIA DEJOHN ANDERSON, CREATURES OF EMPIRE: HOW DOMESTIC ANIMALS TRANSFORMED EARLY AMERICA 97 (2004). 4 GARY L. FRANCIONE, ANIMALS, PROPERTY, AND THE LAW 4 (1995). 5 DEJOHN ANDERSON, supra note 3, at 124. 268 AJIL UNBOUND Vol. 111 http://www.cambridge.org/catalogue/catalogue.asp?isbn=9781107299542 https://toleratedindividuality.files.wordpress.com/2015/02/creatures-of-empire-how-domestic-animals-transformed-early-america.pdf http://www.jstor.org/stable/j.ctt1bw1jm9 http://www.cambridge.org/catalogue/catalogue.asp?isbn=9781107299542 https://toleratedindividuality.files.wordpress.com/2015/02/creatures-of-empire-how-domestic-animals-transformed-early-america.pdf http://www.jstor.org/stable/j.ctt1bw1jm9 https://toleratedindividuality.files.wordpress.com/2015/02/creatures-of-empire-how-domestic-animals-transformed-early-america.pdf https://toleratedindividuality.files.wordpress.com/2015/02/creatures-of-empire-how-domestic-animals-transformed-early-america.pdf The notion of animals as property proved essential to the diffusion of animal farming, particularly dairying, as it justified taking the milk from female animals for human consumption. Milk Colonialism Milk, which can be described as a “conquering colonial commodity,”6 has been caught up in some of the central tensions of nationalist projects both in the metropoles and their colonies. Before the modern colonization area, dairying and animal milk consumption were confined to a few areas: Central and Northern Europe, the Middle East, sub-Saharan Africa, Central Asia, and the Indian subcontinent. To this day, “lactase persistence” (the ability to digest lactose) remains relatively rare among humans: about 75 percent of the world population is lactose intol- erant. Lactase persistence has been tied to population genetics, which explains why it is found primarily in people with ancestry in regions that have a history of animal domestication such as North-Western Europe, South Asia, and the Middle East.7 The fact that animal milk and dairy products are now ubiquitous around the globe, either because they are produced in regions with little or no history of dairying or because they are imported, is a tes- tament to the sway of milk colonialism and international trade law. India, China, Brazil, and New Zealand, all formerly colonized lands, currently figure on the list of the top ten cow’s milk producers in the world. The Asia Pacific is one of the biggest markets for imported condensed milk and other processed dairy products. Deborah Valenze has depicted the global history of milk as the emergence of a culturally malleable, universal commodity, a story “of [the] conquest of space, energy, and dietary preferences.”8 The arrival of domesticated ruminants in colonized lands was driven by European agendas. Settlers had become used to consuming milk prod- ucts back home and were eager to carry on their foodways. Fast forward to the late Nineteenth Century, dairying had become a major industry in Europe and the United States through economic rationalization and new tech- nologies which transformed milk from a substance that spoiled so easily that it had to be consumed on the spot into a commodity that could travel huge distances. Condensed milk—still ubiquitous today in formerly colonized countries of East Asia and Africa in particular—is a paradigmatic imperialist food. Its invention by Gail Borden in the mid-Nineteenth Century was tied to the search for a shelf stable food for soldiers, explorers, and merchants. During the American Civil War, the continental army embraced it as a cheap and transportable source of calories, soon followed by other armed forces, and later by the poor urban classes of European and North America as well as colonizers and colonized people in various regions where fluid animal milk was hard to come by. The interwar period saw the first concerted attempts to industrialize dairying outside of Europe and North America. China is a case in point. Traditionally a nondairying culture, it is now the third largest cow’s milk producer in the world. The Chinese dairy industry originated in American missionaries and foreign businessmen’s efforts to promote milk production and consumption.9 In the postcolonial era, milk colonialism carried on in most conti- nents under the guise of international law and commerce, which is reflected in the number of international trade disputes pertaining to milk since World War II. Since the 1960s, the expansion of international food aid allowed Europe and the United States to dispose of their milk surpluses, all the while maintaining stable prices at home. For instance, “Operation Flood,” a program launched in 1970 and financed in part through the sale of European dairy surpluses through the World Food Program transformed India into the world’s largest milk producer. Reminiscent 6 Jonathan Saha, Milk to Mandalay: Dairy Consumption, Animal History and the Political Geography of Colonial Burma, 54 J. HIST. GEOG. 1, 2 (2016). 7 ANDREA WILEY, RE-IMAGINING MILK: CULTURAL AND BIOLOGICAL PERSPECTIVES 37 (2010). 8 DEBORAH VALENZE, MILK: A LOCAL AND GLOBAL HISTORY 3 (2011). 9 Françoise Sabban, The Taste for Milk in Modern China (1865–1937), in, FOOD CONSUMPTION IN GLOBAL PERSPECTIVE 182, 188–189 (Jakob A. Klein & Anne Murcott eds., 2014). 2017 ANIMAL COLONIALISM: THE CASE OF MILK 269 http://www.sciencedirect.com/science/article/pii/S0305748816300421 http://cw.routledge.com/textbooks/anthropologyofstuff/milk_home.html http://yalebooks.yale.edu/book/9780300188127/milk https://link.springer.com/chapter/10.1057%2F9781137326416_9 http://www.sciencedirect.com/science/article/pii/S0305748816300421 http://cw.routledge.com/textbooks/anthropologyofstuff/milk_home.html http://yalebooks.yale.edu/book/9780300188127/milk https://link.springer.com/chapter/10.1057%2F9781137326416_9 of older forms of animal colonialism, this “white revolution” proceeded in part by replacing Indian bovine breeds with quick fattening, high yield European breeds. The intense, and increasingly global, dairying and dairy food consumption has had dramatic effects on female mammals and their young. By taking milk from animals and feeding it humans, particularly human babies, dairying severs the nursing relationship twice: between lactating animal mothers and their offspring and between human mothers and their offspring. Breastfeeding Colonialism In the early Twentieth Century, lactating animals were conscripted in a colonial reproductive politics aimed at reforming maternity, understood as the embodied experiences of being pregnant, giving birth, and feeding and caring for infants. Since the Nineteenth Century, low birth rates and high infant mortality (which was due in part to the unsanitary animal milk many infants were fed before “safer” substitutes became available) had generated anx- ieties, particularly in the British and French empires. In the metropoles, eugenicist fears developed about national decline and “racial degeneration.” In the colonies, the desire for a larger indigenous labor force and army underlied the declared public health goal of fighting “depopulation” and “improving” population health. Population growth was seen as a form of power and child rearing became a national duty. In this highly racialized populationist project, milk turned into a central nationalist and imperialist tool. Indigenous people and animals were stigmatized as inadequate. Native women were accused of lacking maternal instinct and breastfeeding too long, yet producing mediocre milk. Traditional forms of contraception such as post- partum abstinence and long-term breastfeeding were ridiculed or deplored. Indigenous cows were disparaged as producing milk of inferior quality and in insufficient quantities. A colonial doctor, writing in 1936 about French African colonies thus blames low natality rates among the native population on a combination of prolonged breastfeeding, inferior human milk, and scarce and low quality animal milk.10 Nancy Rose Hunt magisterially described the colonial regulation of breastfeeding in the Belgian Congo as a tool for population increase.11 In the early Twentieth Century, making animal milk available to the colony was thought to promote the fertility of women, both white and black. Early weaning and compulsory bottle-feeding were specifically prescribed to black mothers to reduce their breast milk supply and encourage return to full fertility. The Belgian Congo was not an isolated case as comparable colonial policies were developed in Malaya, Sudan, French West Africa, Vanuatu and Fiji, and the Philippines.12 Improving or modernizing maternity meant replacing the human breast by cow’s milk. That was also true in the metropoles. Milk depots and clinics multiplied in European and American cities, distributing sanitized animal milk at a time when pasteurization and formula were not widely available. In the colonies, early childhood interventions aimed at challenging indigenous traditions of mothering in the name of civilization, modernity, and scientific medicine. Early Twentieth Century milk depots in the Philippines are illustrative of this dynamic.13 Through them, the American colonial government hoped to create “enlightened mothers,” instructed on the “proper” care of infants, particularly in terms of sanitation and hygiene. The depots dispensed free or subsidized pasteurized cow’s milk obtained, whenever possible, by estab- lishing their own dairies populated by cows imported from Australia. 10 J.L.F. Cazanove, La Question du Lait dans les Colonies Africaines, 9 AFRICA 227, 231 (1936) (my translation). 11 Nancy Rose Hunt, “Le Bébé en Brousse”: European Women, African Birth Spacing and Colonial Intervention in Breast Feeding in the Belgian Congo, 21 INT’L J. AFR. HIST. STUD. 401 (1988). 12 Tehila Sasson, Milking the Third World? Humanitarianism, Capitalism, and the Moral Economy of the Nestlé Boycott, 121 AM. HIST. REV. 1196, 1200 (2016). 13 Mina Roces, Filipino Elite Women and Public Health in the American Colonial Era, 1906–1940, 26 WOMEN’S HIST. REV. 477, 484 (2017). 270 AJIL UNBOUND Vol. 111 https://www.jstor.org/stable/1155626?seq=1#page_scan_tab_contents https://www.jstor.org/stable/219448?seq=1#page_scan_tab_contents https://academic.oup.com/ahr/article-abstract/121/4/1196/2581604/Milking-the-Third-World-Humanitarianism-Capitalism?redirectedFrom=fulltext http://www.tandfonline.com/doi/abs/10.1080/09612025.2016.1194076?journalCode=rwhr20 https://www.jstor.org/stable/1155626?seq=1#page_scan_tab_contents https://www.jstor.org/stable/219448?seq=1#page_scan_tab_contents https://academic.oup.com/ahr/article-abstract/121/4/1196/2581604/Milking-the-Third-World-Humanitarianism-Capitalism?redirectedFrom=fulltext http://www.tandfonline.com/doi/abs/10.1080/09612025.2016.1194076?journalCode=rwhr20 It is now well known that the spread of animal milk, particularly in the form of infant formula, has had dele- terious effects on human babies and their mothers, especially in former colonies. However, the harm to animals ushered in by the globalization of milk consumption is less familiar. Female animals bred and exploited for their milk live a particularly miserable existence, exposed to extreme physiological demands. They are maintained in a quasi-constant state of pregnancy and lactation via forced insemination or other forms of reproductive technol- ogies, only to have their newborns removed from them so that humans may express their milk. There is a special harm, for both human and nonhuman mammals in being prevented from nursing. As Sherry Colb has written, “[l]ike other mammals, cow mothers are extremely attached to their newborn babies and want nothing more than to be able to nurse them. The babies feel this way too, and they find comfort, nourishment, and pleasure in nursing on their mothers.”14 Under natural conditions, the weaning process involves a gradual reduction in milk intake, accompanied by increasing social independence from the mother and increasing intake of solid food. By contrast, farm animals are typically weaned abruptly by separating the young from the mother, often within hours of birth. In this system, both baby animals and their mothers show a distinctive distress response when they are separated —both bellow for several days, sometimes weeks with grief. Conclusion: Toward a Trans-Species Right to Breastfeed? While international law has begun to address issues such as endangered species and biodiversity, the welfare of animals, let alone lactating animals, remains unaddressed. Yet, could it be that lactation, because it is common to all mammals, represents a promising starting point for advocating in favor of stronger international animal welfare protection? In other words, one strategy to promote global animal law, both as a research program and as a branch of law, could be to connect it with other international legal initiatives such as women and children’s rights. This could be done in an ecofeminist vein, that is, by taking seriously the idea that the oppression of animals and human females is interconnected and mutually reinforcing. Milk is a quintessentially intersectional issue, cutting across the human/animal divide. It is produced by female mammals of all species, including women. As pioneering ecofeminist Carol Adams likes to point out, all milk from female animals is “breast milk.” One avenue to advance the global animal law agenda may be to reorient interna- tional breastfeeding advocacy toward promoting the welfare of lactating animals of all species, rather than humans only. International human rights lawyers have considered the idea of a woman’s right to breastfeed and a child’s right to be breastfed for some time. No such rights have been recognized yet, but the World Health Organization (WHO) and the United Nations Children’s Fund developed the International Code of Marketing of Breast-Milk Substitutes in 1981 as a health policy framework for breastfeeding promotion. Though the WHO lacks enforce- ment mechanisms, the Code’s recommendations were incorporated into many domestic laws and successfully pressured Nestlé and its like to change their marketing strategies. Why not expand the movement to other lactating animals and their offspring? This shift would vindicate Katsi Cook’s beautiful insight that the mother’s body is the first environment,15 and as such should be protected regardless of species. 14 Sherry F. Colb, “Never Having Loved at All”: An Overlooked Interest that Grounds the Abortion Right, 48 CONN. L. REV. 933, 952–953 (2016). 15 WINONA LADUKE, ALL OUR RELATIONS: NATIVE STRUGGLES FOR LAND AND LIFE 22 (1999) (quoting Katsi Cook). 2017 ANIMAL COLONIALISM: THE CASE OF MILK 271 http://scholarship.law.cornell.edu/cgi/viewcontent.cgi?article=2614&context=facpub https://www.haymarketbooks.org/books/898-all-our-relations http://scholarship.law.cornell.edu/cgi/viewcontent.cgi?article=2614&context=facpub https://www.haymarketbooks.org/books/898-all-our-relations Animal Colonialism: The Case of Milk Animal Colonialism Milk Colonialism Breastfeeding Colonialism Conclusion: Toward a Trans-Species Right to Breastfeed? work_2t6g3oskojfivf3rsvm5nb3wjm ---- The French Pox 265J Fam Plann Reprod Health Care 2006: 32(4) HISTORY OF CONTRACEPTION Aetiology and epidemiology Syphilis (also known as ‘The French Pox’) landed on England’s shores in about 1493. The term ‘French Pox’ was derived from the belief that the disease originally travelled from the New World and through France before arriving in England’s green and pleasant land. Controversially, it was believed to be Christopher Columbus’ own ship that brought such misery but this was not suggested until several decades after the event. Smallpox and plague exacted a much higher toll on human life and a lot more quickly than syphilis, yet it still became one of the most prolific and feared fatal diseases for over 450 years. The causative agent for syphilis is a spirochaete bacterium, Treponema pallidum, which is carried through the mucous membranes of the mouth, anus or genitals. The early Tudors had no understanding of bacteria or viruses. They believed, as did the ancient Greeks, in humoral medicine, whereby illness was lodged with the individual who was out of ‘balance’ in some way. It was also thought possible to become ill from bad smells or poisons lodged in foods. The Tudors did understand, however, that plagues came in waves. The Black Death killed 30–50% of the population. These were the massive medical dramas; lower-ranking illnesses tended not to be well recorded. It is therefore interesting for modern-day scholars to find actual reference to both the first known cases of a disease and also some logging from notes, fairly early on, of the development and spread of the epidemic. As early as 1505, clusters of cases began to be recorded. Twelve years after the first notes of the disease may not be considered especially rapid by modern standards but by Tudor standards this was fast. Numerous doctors were discussing cases of syphilis in the last decade of the 15th century, especially in the Italian city-states. Somewhere, out there in the medical community, were individuals who registered the movement of the disease and the nature of the symptoms. The natural scientists of common sense were reacting and asking the right questions such as ‘How?’ and ‘Why?’. The reader must appreciate that in Tudor England there were no esteemed professional publications, such as this one, in which information might be shared and disseminated. Medical schools (as we know them) did not exist. A doctor or surgeon learned their profession as an apprentice to a licensed medical practitioner or, for a rich individual, there was university first to study medicine followed by an apprenticeship. The university did provide a forum for philosophy, including debate. Unfortunately, most of the content of the studies was based on the beliefs of medical philosophers who lived centuries before the birth of Christ. It is important to distinguish between physicians and surgeons. Physicians would have been what we would generally regard as general practitioners, and would have been university trained. Surgeons, who were of a lower social status, would have been ‘knife men’; it was the barber surgeons who would be more likely to have done an apprenticeship. By the mid 1500s, rich and poor alike were being infected by the Pox and a wide range of names for the disease appears in the literature and doctors’ notes of the period: Hot Piss, The Clap, Winchester Goose (the Bishops of Winchester held the taxation on whore houses), the French Disease, the French Embrace, the Infinite Malady and Syphilis. Syphilis is an interesting disease to track since it seems to have gone through some changes or mutation in terms of how symptoms were presented. Indeed, the great challenge is to ascertain whether this is the disease the contemporary doctors’ notes say it is! A further complicating factor is that syphilis modified its behaviour faster than any other disease ever known. There does not seem to be (as we know it) at the beginning of the disease a small hard chancre; instead the body was rapidly covered in pus-filled lesions that seem to correspond to the secondary stage, usually appearing several weeks after the first stage comprising just a small ulcer. The secondary stage was highly infectious. There was confusion, understandably, that this might be a form of leprosy or scabies. This presentation seems to have lasted from a matter of months to just over a year before subsiding, whereupon a cure seemed apparent. In fact, the disease was usually lying dormant and would reappear some years later as tertiary syphilis. Naturally, medical practitioners thought reoccurrences represented re- infection. All this discussion would have been of little concern to the Tudor physician. He would be convinced that sexual contact and the stars had resulted in the body’s humors being thrown out of balance in a hot, dry state (Table 1). The pus-filled blisters were seen as vents for the yellow bile humor. Like bubbling porridge, the heat was so great the skin was boiling. The hot urine further convinced medical practitioners of the extreme heat and fire elements of the Pox. God, in this governance of the stars, would also play His part in this illness as divine retribution for the “licentious and beastly disorder” of the morally degenerate. For it was very early on in the passage of the disease that poxing of the genitals could be seen and it was but a short journey to lay the blame firmly at the whorehouse doors. The Tudors regarded God as a Michelangelo figure who could stretch out His arm and move the planets about like billiard balls, with the resultant effect on air, tides and the humors of man. The astrological sign of Ares (the Greek god of war), which is hot and dry, would be seen as controlling some of the heavens when syphilis was rampant. The French Pox Lesley Smith J Fam Plann Reprod Health Care 2006; 32(4): 265–266 Tutbury Castle, Tutbury, UK Lesley Smith, Curator Correspondence to: Lesley Smith, Tutbury Castle, Tutbury, Staffordshire DE13 9JF, UK. E-mail: info@tutburycastle.com Table 1 The humors and their qualitiesa Humor Fluid Heat/moisture Element Sanguine Blood Hot and moist Air Choleric Yellow bile Hot and dry Fire Phlegmatic Phlegm Cold and moist Water Melancholic Black bile Cold and dry Earth aSource: Sex, Society and Medieval Women by N M Heckel. 265-266 - JFPRHC Oct 06 9/20/06 4:08 PM Page 1 o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://jfp rh c.b m j.co m / J F a m P la n n R e p ro d H e a lth C a re : first p u b lish e d a s 1 0 .1 7 8 3 /1 4 7 1 1 8 9 0 6 7 7 8 5 8 6 6 0 6 o n 1 O cto b e r 2 0 0 6 . D o w n lo a d e d fro m http://jfprhc.bmj.com/ Treatment and prevention Doctors set about the business of trying to cure, and in some cases try and prevent, this onslaught on society. The main treatment for syphilis in Tudor times involved the use of mercury. Mercury ointment had been used for centuries by Arabians to treat skin disorders, particularly scabies. ‘Quicksilver’ sales rose dramatically. Patients were rubbed in mercury ointment, drank solutions of it, inhaled it and – to really liven up a dull afternoon – they could bend over and have their genitals injected with it. The source of the latter information is an extraordinary illustration showing the treatment together with other tortuous efforts. Then heat was applied using steam baths: barrel-style with the individual’s head sticking out or alternatively sauna- style rooms for mass treatment. Iatrogenic illness was typical, and so presumably was aversion therapy for visiting a whorehouse again. Some patients were famous, such as Mary Queen of Scots’ second husband, the ghastly Darnley, who was treated in Glasgow for the French Pox. There has also been much speculation about Henry VIII, but real medical evidence is slim. Even Shakespeare has been the subject of great debate as to whether he was a sufferer, virtually only on the basis that he wrote frequently and accurately about the symptoms and treatment of syphilis. The poor Bard has been accused of just about everything else too, from bisexuality to adultery. Shakespeare was a fantastic observer, which might explain his ability to write about the Pox, though I might point out he wrote about kings and fairies too! There is a famous medical poem (usually cited as being published in 1530, but it is thought that it was probably written several years earlier) by Giroloma Frascastoro entitled ‘Syphilis sive morbus Gallicus’ (‘Syphilis or the French Disease’). Contagion, treatment and symptoms all appear in this fine Latin work, which tells the story of Syphilis, the shepherd who contracted the disease by offending the gods. Many believe it was Frascastoro’s poem that gave the disease its name. Steps were taken to try and prevent the disease spreading too wildly. Henry VIII closed the whorehouses in 1546 and the boy king, his son Edward, re-opened them in 1552. The opportunity to regain this source of taxation revenue must have been too tempting. Condoms of leather and gut were used in England and the prophylactic of “hard-pissing” was well thought of. “Hard-pissing” involved a prostitute having two chamber pots under the bed: one for her own use and one for her clients who immediately after ejaculation were advised to urinate as hard as they could to flush out any bodily fluids. Even respectable, general usage household management books gave recipes for the making up of cures and salves for the French Pox. Gervase Markham, in the late 16th century, wrote in his book, The English Housewife: “Take quicksilver and kill it with fasting spittle, then take verdigris, Arabic, turpentine, oil olive, and populeon, and mix them together to one entire ointment, and anoint the sores therewith, and keep the party exceeding warm. Or otherwise, take of alum burned, of resin, frankincense, populeon, oil of roses, oil de bay, oil olive, green copperas, verdigris, white lead, mercury sublimate, of each a pretty quantity but of alum most, then beat to powder the simples that are hard, and melt your oils, and cast in your powders and stir all well together, then strain them through a cloth, and apply it warm to the sores; or else take of capon’s grease that hath touched no water, the juice of rue and the fine powder of pepper, and mix them together to an ointment, and apply it round about the sores, but let it not come into the sores, and it will dry them up”. Future articles This article only deals with the first hundred years of the onslaught of syphilis. The next few hundred years, until the antibiotic revolution of the 1940s, are equally as fascinating. The events of those centuries are the subject of another article. Readers may be interested to note that the next article in the series will be on the subject of childbirth. The author invites readers who would like to find out more about any of the articles in this series to write to her personally and all correspondence will be answered. Acknowledgements The author would like to thank the following individuals for their help and advice: Dr R Arnott, Sub-Dean of Medicine and Director of The Medical School, University of Birmingham, Birmingham, Dr G Williams, Curator of the British Museum, London and Dr R K Dart, Consultant Microbiologist. Bibliography 1 Markham, Gervase (1568?–1637). The English Housewife. Best, Michael R (ed.) (translated from the primary source). Montreal and Kingston, Canada: McGill-Queen’s University Press, 1986. A contemporary piece written to advise housewives on wide ranging topics from home medicine to cooking to brewing. The Renaissance woman’s handbook. 2 Heckel NM. Sex, Society and Medieval Women. http://www.lib. rochester.edu/camelot/medsex/text.htm [Accessed 16 July 2006]. 3 Leyser, Henrietta. Medieval Women. London, UK: Phoenix Press, 1995. 4 Haynes, Alan. Sex in Elizabethan England. Stroud, UK: Sutton Publishing, 1997. 5 Petrie, Hugh. The French Pox. Bristol, UK: Stuart Press, 1999. 6 Various publications available in the The Wellcome Library for the History and Understanding of Medicine, London, UK. Every doctor who enjoys the history of medicine should be a member. About the Author Lesley Smith is an Elizabethan historian, currently studying for the degree of MPhil in the History of Medicine at Birmingham University Medical School. She has appeared in 24 television programmes including Tony Robinson’s The Worst Jobs in History, and is currently working on an eight-part 1-hour major series on the Private Lives of Women. Lesley is well known as a public speaker, and on 23 November 2006 Lesley will be speaking at the Faculty of Family Planning and Reproductive Health Care Current Choices Conference at the Royal Society of Medicine in London. 266 J Fam Plann Reprod Health Care 2006: 32(4) HISTORY OF CONTRACEPTION “The whorehouse client puts his hand in the fire.” C a rt o o n b y L es le y S m it h 265-266 - JFPRHC Oct 06 9/20/06 4:08 PM Page 2 o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://jfp rh c.b m j.co m / J F a m P la n n R e p ro d H e a lth C a re : first p u b lish e d a s 1 0 .1 7 8 3 /1 4 7 1 1 8 9 0 6 7 7 8 5 8 6 6 0 6 o n 1 O cto b e r 2 0 0 6 . D o w n lo a d e d fro m http://jfprhc.bmj.com/ work_2xeh7rdbpvcc7iyhf2uetxooq4 ---- BA602809.pdf Su: Successful Invader 765 HOW TO BECOME A SUCCESSFUL INVADER§ NAN-YAO SU Department of Department of Entomology & Nematology, Fort Lauderdale Research & Education Center, University of Florida, Davie, Florida 33314; E-mail: nysu@ufl.edu §Summarized from a presentation and discussions at the “Native or Invasive - Florida Harbors Everyone” Symposium at the Annual Meeting of the Florida Entomological Society, 24 July 2012, Jupiter, Florida. ABSTRACT Most invasive species hitchhike on human transportation, and their close associations with human activity increase their chances of uptake. Once aboard, potential invaders have to survive the journey, and those with traits such as being a general feeder or tolerance to a wide range of environmental conditions tend to survive the transportation better. Similar traits are generally considered to also aid their establishment in new habitats, but stud- ies showed that the propagule pressure, not any of the species-specific traits, is the most important factor contributing to their successful establishment. Higher propagule pressure, i.e., repeated invasions of larger numbers of individuals, reduces Allee effects and aids the population growth of invasive species in alien lands. Coined as the invasive bridgehead ef- fect, repeated introduction also selects a more invasive population that serves as the source of further invasions to other areas. Invasive species is the consequence of homogenocene (our current ecological epoch with diminished biodiversity and increasing similarity among ecosystems worldwide) that began with the Columbian Exchange of the 15th century and possibly the Pax Mongolica of the 13-14th century. Anthropogenic movement of goods among major cities will only accelerate, and the heightened propagule pressure will increase the number of invasive species for as long as the current practices of global commercial activi- ties continue. Key Words: propagule pressure, invasive bridgehead effect, homogenocene, Columbian Ex- change RESUMEN La mayoría de las especies invasoras entran los países conjuntamente con el transporte humano y sus estrechas asociaciones con las actividades humanas aumentan sus posibilida- des de admisión. Una vez a bordo, los invasores potenciales tienen que sobrevivir el viaje y las species con características tales como ser un consumidor general o una tolerancia a una amplia gama de condiciones ambientales tienden a sobrevivir el transporte mejor. También, por lo general se considera que las características similares ayudan su establecimiento en nuevos hábitats, pero los estudios muestran que la presión de propágulos, no unas de las características específicas de la especie, es el factor más importante que contribuye a su esta- blecimiento exitoso. Mayor presión de propágulos, es decir, repetidas invasiones de un mayor número de individuos, reduce los efectos de Allee y ayuda en el crecimiento de la población de las especies invasoras en paises exóticos. Llamado como el efecto invasivo de la cabeza de puente, la introducción repetida también selecciona una población más invasiva que sirve como una fuente para más invasiones a otras áreas. Las especies invasoras son la consecuen- cia de homogenocene (nuestra época ecológica actual con la disminución de la biodiversidad y el aumento de similitud entre los ecosistemas en todo el mundo), que comenzó con el Intercambio Colombiano del siglo 15 y posiblemente la Pax Mongolica del siglo 13 al 14. El movimiento antropogénico de mercancía entre las principales ciudades seguirá aceleraran- dose, y la elevada presión de propágulos aumentará el número de especies invasoras por el tiempo que las prácticas actuales de actividades comerciales globales continúen. Palabras Clave: presión de propágulos, efecto invasivo de la cabeza de puente, homogenoce- ne, Intercambio Colombiano Of the over 12,500 insect species found in Flor- ida in 1995, 988 (7.9%) were listed as “non-na- tive” species (Frank & McCoy 1995), but not all of them are considered “invasive.” Invasive species are defined as the non-native “pest” species, i.e., those that adversely affect environment, economy and human health (Anonymous 1999). Pest sta- tus is determined primarily by human value and 766 Florida Entomologist 96(3) September 2013 perception. Following its successful introduction to control cacti (Opuntia spp.) (Caryophyllales: Cactaceae) in Australia in 1925, for example, the moth Cactoblastis cactorum Berg (Lepidoptera: Pyralidae) was intentionally introduced to sev- eral Caribbean islands in 1957 (Frank & McCoy 1995) to control Opuntia weeds. By 1989, C. cac- torum had spread to the Florida Keys where it became a “pest” because it began to attack two cati, O. spinosissima Martyn (Mill.) and O. triac- antha (Willdenow), which are considered to have value because they are designated rare (Habeck & Bennett 1990). Certain species-specific characteristics are of- ten regarded as traits that render some species more “invasive.” These include, among others, high dispersal ability (better survival of transpor- tation), association with human activity (increas- ing opportunities for migration), ecological com- petence (better survival in a new environment), rapid and/or placid reproduction (e.g., sexual and asexual reproduction), and rapid population growth. The usefulness of the list of such “inva- sive” traits has been questioned because many species with these traits have never become in- vasive (Kolar & Lodge 2001). These traits may be “necessary” instead of “sufficient,” but they still serve as the guide to understand the likelihood of a species to become invasive. STEPS TOWARD SUCCESSFUL INVASION AND ES- TABLISHMENT Uptake and Migration Most cases of species invasions are human- mediated. Living organisms extend their ranges naturally, but natural extension of most species occurs less frequently and at much shorter dis- tances than anthropogenic events. Because most invasive species hitchhike on human transpor- tation, a close association with human activity increases their chances of uptake. Cockroaches, rodents and some termite species tend to live near human habitat and are frequently transported. The Formosan subterranean termite, Copto- termes formosanus Shiraki (Isoptera: Rhinoter- mitidae), for example, tends to infest man-made structures (hence the common name in its native China is “house termite”), and is one of the most widely distributed subterranean termites (Rust & Su 2012). The West Indies powderpost termite, Cryptotermes brevis Walker (Isoptera: Kaloter- mitidae), often hitchhikes in wooden furniture or picture frames (and thus nicknamed “furniture termite”), and is found in more regions in the world than any other termite species. Once aboard, the stowaway has to survive the journey (Fig. 1). General feeders that can tolerate a wider range of temperature and humidity tend to survive better during the transportation, but some species may create conditions suitable for their survival. Incipient colonies of C. formosa- nus, for example, may seal off the nest after tun- neling into wet wood, and create moist conditions in their food source to survive the journey. Surviving in a New Environment: Propagule Pressure Species-specific traits that better serve for survival during transportation (i.e., generalist feeders, and tolerance to a wide range of environ- mental conditions) are usually considered to aid the invaders to survive in new environment. Co- lautti et al. (2006) who studied 14 invasive char- acteristics (i.e., features associated with invasive species), however, found that propagule pressure was the only consistent predictor of invasive- ness. Physiological tolerance and body size did not have any effect on a species’ ability to invade a foreign land. Propagule pressure is defined as the measure of the total number of individuals being introduced, and is the function of the num- ber of introduction events and the mean number of introduced individuals per event (Lockwood et al. 2005) (Fig. 1). Generally speaking, more intro- duction events with more individuals per event increase the propagule pressure and hence the chance of successful establishment (Colautti et al. 2006). Propagule pressure is affected by inva- sion pathways that are closely associated with human activities. Using the mitochondrial DNA sequences, Yang et al. (2012) examined the inva- sion pathways of the fire ant, Solenopsis invicta Fig. 1. Steps for a species to become a successful in- vader in alien lands. Su: Successful Invader 767 Buren (Hymenoptera: Formicidae), into China and showed that this species was most likely im- ported from Austin, Texas, which also ranked the highest in exporting goods to China. The frequent traffic of goods from Austin to China apparently increased the propagule pressure and aided its successful invasion. Population Growth and Allee Effect The notion that density dependent factors gov- ern the upper limit of population size goes back as far as Malthus and forms the backdrop for natural selection. However, low population den- sity during the early stage of species establish- ment may also inhibit population growth due to infrequent intra-species encounters. Coined the “Allee effect,” this principle was demonstrated in a series of studies using goldfish (Allee 1931; Al- lee & Bowen 1932) during the time when most ecologists were focusing on the adverse effects of overcrowding and competition on individual sur- vival. Overcrowding increased individual com- petition and mortality thus inhibits population growth, but according to the Allee effect, under- crowding also deters population growth due to these aggregation-related consequences. Mecha- nisms contributing to the Allee effect may include mate limitation, cooperative defense, cooperative feeding, and environmental alternation through aggregation. Leung et al. (2004), for example, used prediction models to study zebra mussel invasions in 1,589 inland lakes of Michigan and found that models that included the Allee effect were better in predicting its invasion. Due to the Allee effect, higher propagule pressure increases the probability for invasive species to establish in a new environment, and to increase its population (Fig. 1). Range Expansion and Invasive Bridgehead Effect Many species do not establish in alien lands despite being frequently transported by man, be it intentionally or accidentally (Lockwood et al. 2005). The frequent anthropogenic movement of these species may act as a process to select a particular population that is more invasive than others. Once established, the selected population, instead of the populations in the native land, may become the source of further invasions to other re- gions and range expansion (Fig. 1). This phenom- enon was termed “invasive bridgehead effect” by Lombaert et al. (2010) who tracked the invasive pathways of the Asian ladybeetle, Harmonia axy- ridis (HA) by analyzing the microsatellite genetic variation among its populations worldwide. There have been repeated attempts to release H. axyri- dis as the biological control agent against aphids since early 1900s, but all failed. Since 1988, H. axyridis has been found unexpectedly in multiple areas. Some of these populations were eventu- ally successful in the control of soybean aphids, but others became nuisance pests due to their unpleasant odors when they overwinter indoors in large numbers. A genetic study by Lombaert et al. (2010) showed that H. axyridis from its na- tive Asia established its bridgehead in eastern U.S. in 1988, from which it was later introduced to South America, South Africa and Europe. The study of S. invicta invasive pathways to China of- fers another example of bridgehead effect (Yang et al. 2012). A comparison of the genetic varia- tions among 27 populations of S. invicta (10 in China and 17 in the U.S.) showed that most popu- lations in China appeared to have originated from Wuchuan in southwest Guangdong Province, P.R. China, in which this ant species first established, and served as the bridgehead population to other populations in China. HOMOGENOCENE The process of successful establishment by in- vasive species as shown in Fig. 1 is part of a larger trend of “homogenocene” which was termed by Samways (1999) to characterize our current eco- logical era as an epoch with diminished biodiver- sity and increasing similarity among ecosystems worldwide. Homogenocene results from anthro- pogenic movement of organisms worldwide, and most attribute its beginning to the “Columbian Exchange,” i.e. the large scale exchange of goods, and macro- and microorganisms following the 1492 voyage of Christopher Columbus to the New World (Mann 2011). Connection of 2 once-sepa- rated Hemispheres prompted the movements of numerous organisms, but before the Columbian Exchange, there was another dramatic connec- tion of 2 largely separated worlds during the Pax Mongolica via the Silk Road. Pax Mongolica: 13th-14th Century Following a series of wars waged through most of the 11th century, Genghis Khan and his descen- dents built the largest continuous empire in hu- man history that stretched from the Pacific Ocean to the Caspian Sea and today’s Moscow. The Mon- gol Empire was partitioned into 4 branches, and despite political tensions and constant squabbles among them, trade routes were kept open, and exchanges of goods, people, and ideas changed the lives of those inhabited within the Mongol Em- pire and the neighboring nations. The Silk Road (started in the Han dynasty, 206 BCE – 220 CE) was reopened as the main land route connecting China with Europe. The Maritime Silk Road con- nected China through SE Asia, the Indian Ocean, the Arabian Sea, the Persian Gulf, and the Red 768 Florida Entomologist 96(3) September 2013 Sea to East Africa. Through these networks of trade routes, a global commerce flourished for the first time in human history, and productiv- ity and populations of nations within the trade zone grew rapidly (Abu-Lughod 1989). The Yum system (a series of relay stations at every 32-40 km along the major routes to supply fresh horses and other travel accommodations) that was origi- nally established to secure communication among Mongol troops, provided vital needs for traveling merchants, and the trade routes were manned by Mongol soldiers for safe passage. Chinese silk, exotic spices, Indian cotton, sugar and new crops such as carrots, turnips and buckwheat were in- troduced to Europe by merchants from the East. In addition to commodities and products, people and information also flowed through the Silk Road. The Venetian merchant, Marco Polo traveled with his father and uncle to China (Ca- thay) and the book of his travel and adventure, “The Travel of Marco Polo” introduced Europeans to the exotic countries in the east, and stirred imagination of many including Christopher Co- lumbus (Latham 1958). Introduction of Chinese innovations such as paper, printing, gunpowder, firearms and the magnetic compass were con- sidered underlying factors for the emergence of Renaissance in Europe (Weatherford 2004). Through the same trade routes, the pathogen of Plague, the bacterium Yersinia pestis (Lehmann and Neumann 1896) van Loghem 1944, was also brought to Europe by its carrier, the Oriental rat flea, Xenopsylla cheopis (Rothschild) (Siphonap- tera: Pulicidae) on rodents that hitchhiked trade ships from the Orient. The disease ravaged Asia with an estimated 25 million victims before enter- ing Europe (Kohn 2008). Between 1347 and 1353, Plague killed one third of the European popula- tion, and profoundly altered the course of Euro- pean history. The most significant impact of Pax Mongolica to homogenocene, however, is that sto- ries of lands with abundance of gold, treasures, and exotic spices flowing through the Silk Road led Europeans to the age of discovery, and the Co- lumbian Exchange. Columbian Exchange Columbus’ voyage in 1492 connected 2 Hemi- spheres and promoted a dramatic and widespread exchange of organisms between them. New World crops such as maize, potato, tomato, tobacco, sweet potato, cacao, vanilla, pineapple, chili pep- per, peanut, sunflower, and papaya were spread to and deeply affected lives of those in the Old World. Introduction of maize, potato and sweet po- tato to China, for example, turned marginal lands of mountainous terrains (which were unsuitable for cultivating traditional crops such as rice and wheat) into productive lands that contributed to the doubling of the Chinese population (Mann 2011) in the Qing dynasty (1644 to 1912). Potato was singularly responsible for the population ex- plosion in Ireland as well as the Great Irish Fam- ine (1845-1852) when the crops were decimated by potato blight. Before the 1500s, there were no tomatoes in Italian cuisine, no chocolate in Swit- zerland, no pineapples in Hawaii, no chili peppers in Thai or Indian food, no potatoes in the German diet, and no rubber trees in Malaysia. Almost as many plant species were also brought from the Old to New World, including apple, banana, black pepper, coffee, citrus, garlic, onion, peach, soy- bean, sugarcane, rice, wheat, and watermelon. Domesticated animals such as horse, chicken, donkey, pig, earthworm, honey bee and silkworm were introduced to the New World and changed the life style of Native Americans. As with Plague during the Pax Mongolica, many infectious dis- eases including malaria, small pox, chicken pox, cholera, leprosy, bubonic plague, yellow fever, ty- phoid, and measles were also brought from the Old to New World. Of these, the most devastating was small pox that killed 80-90% of Native Amer- ican populations (Mann 2011). Columbus’ crews who contracted syphilis spread it to European populations when some of them later joined the Spanish army to invade Italy. Edible plants and domestic animals were intentionally introduced, but diseases and other organisms were acciden- tally transferred, and many became invasive, e.g., brown rats, zebra mussels, tumbleweed (Salsola spp.; Caryophylalles: Amarantaceae), wild oat, and ascomycete microfungi (Ophiostoma spp.) responsible for Dutch elm disease. Some species such as Kudzu that was intentionally introduced (to prevent soil erosion) became a pest species, while others such as the yeast, Saccharomyces bayanus Saccardo, which was accidentally intro- duced from South America was later used for pro- ducing lager beer. CONCLUSION As shown in Fig. 1, propagule pressure is the major factor contributing to the increase of inva- sive species across the globe. Beginning with Pax Mongolica, and later the Columbian Exchange, anthropogenic movement of goods among major cities has increased over time, and this trend will only accelerate. This will heighten propa- gule pressure to provide more opportunities for potential invasive species, and to select for a more invasive population within a species. The number of invasive species, thus, will only in- crease for as long as current practices of global commercial activities continue. Between cities with heavy traffic, a more targeted quarantine/ inspection measure focusing on potential inva- sive species of the source region may be one so- lution to intercept their shipments and reduce propagule pressure. Su: Successful Invader 769 ACKNOWLEDEGMENTS I would like to thank P. Bardunias and A. Mullins (University of Florida) for review of the initial draft of this article. REFERENCES CITED ABU-LUGHOD, J. L. 1989. Before European hegemony. The world system A.D. 1250-1350. Oxford Univer- sity Press, New York, NY. 443 pp. ALLEE, W. C. 1931. Animal aggregation. A study in general sociology. University of Chicago Press, Chicago, IL. ALLEE, W. C., AND BOWEN, E. 1931. Study in animal aggregation: mass protection against colloidal silver among goldfishes. J. Exp. Zool. 61: 185-207. ANONYMOUS. 1999. Executive Order 13112 of February 3, 1999: Invasive Species. Federal Register 64: 6183- 6186. COLAUTTI, R. I., GRIGOROVICH, I. A., AND MACISSAC, H. J. 2006. Propagule pressure: a null model for inva- sion. Biol. Invasions 8: 1023-1037. FRANK, J. H., AND MCCOY, E. D. 1995. Introduction to insect behavioral ecology: The good, the bad, and the beautiful: Non-indigenous species in Florida. Invasive adventive insects and other organisms in Florida. Florida Entomol. 78: 1-15. HABECK, D. H., AND BENNETT, F. D. 1990. Cactoblastis cactorum Berg. (Lepidoptera: Pyralidae), a phycitine new to Florida. Florida Dept. Agric. Consum. Serv., Divn. Pl. Industry, Entomol. Circ. 333: 1-4. KOHN, G. C. 2008. Encyclopedia of plague and pesti- lence: from ancient times to the present. Infobase Publishing, New York, NY. pp. 529. KOLAR, C. S., AND LODGE, D. M. 2001. Progress in in- vasion biology: predicting invaders. Trends in Ecol- ogy & Evolution, 16: 199–204. (doi:10.1016/S0169- 5347(01) 02101-2). LATHAM, R. 1958. The travels of Marco Polo. Penguin Books, London. 380 pp. LEUNG, B., DRAKE, J. M., AND LODGE, D. M. 2004. Pre- dicting invasions: propagule pressure and the grav- ity of Allee effects. Ecology 85: 1651-1660. LOCKWOOD, J., CASSEY, L. P., AND BLACKBURN, T. 2005. The role of propagule pressure in explaining species invasions. Trends in Ecology & Evolution, 20: 223- 228 (doi:10.1016/j.tree.2005.02.004) LOMBAERT, E., GUILLEMAUD, T., CORNUET, J-M., MA- LAUSA, T., AND FACON, B. 2010. Bridgehead effect in the worldwide invasion of the biocontrol harlequin ladybird. PLoS ONE 5: e9743 MANN, C. C. 2011. 1493. Uncovering the new world Columbus created. Alfred A. Knopf. New York, NY. 2516 pp. RUST, M. K., AND SU, N.-Y. 2012. Managing social in- sects of urban importance. Annu. Rev. Entomol. 57: 355-375 SAMWAYS, M. 1999. Translocating fauna to foreign lands: here comes the Homogenocene. J. Insect Con- serv. 3: 65-66. WEATHERFORD, J. 2004. Ghenghis Khan and the mak- ing of the modern world. Crown Publishers, New York, NY. 312 pp. YANG, C.-C., ASCUNCE, M. S., LUO, L.-Z., SHAO, J.-G. AND SHIH, C.-J. 2012. Propagule pressure and colony social organization are associated with the success- ful invasion and rapid range expansion of fire ants in China. Mol. Ecol. 21: 817-833 work_3c6me2etdvb7hj7nh7fpspushq ---- wp-p1m-38.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-38.ebi.ac.uk no 218194225 Params is empty 218194225 exception Params is empty 2021/04/06-02:09:19 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. Message ID: 218194225 (wp-p1m-38.ebi.ac.uk) Time: 2021/04/06 02:09:19 If you need further help, please send an email to PMC. Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_3cc5phisrnhkxeawgrrl6aglhe ---- Genitourin Med 1996;72:440-442 STD awareness today 0 P Bleker Introduction Nowadays, the medical interest for, and knowledge of, infectious diseases and espe- cially sexually transmitted diseases (STDs) is concentrated in specialist medical societies like the MSSVD in the UK and the NVSSOA in The Netherlands. However, most patients pre- senting with STD-related symptoms are not seen by members of those societies but by gen- eral practioners or medical specialists like gynaecologists, urologists, pediatricians and others. Moreover, the public is not sufficiently aware of the significance of minor symptoms, possibly related to STD and not interested enough in the prevention of STD. Therefore it seems to be the duty of the STD societies, not only to raise the knowledge of those diseases within their circles but also to spread the STD awareness and STD knowledge among other workers in health care and even among the general public. Academic Medical Centre, Department of Obstetrics and Gynaecology, PO Box 22700, 1100 DE Amsterdam, The Netherlands O P Bleker Accepted for publication 1 August 1996 History The present HIV epidemic is of course not the first time that the world (and especially Europe) has been faced with a widespread STD. According to most historians, at the end of the fifteenth century, Christopher Columbus and his fellow travellers introduced syphilis in Europe, especially in Naples. King Charles VIII of France raised an army of 32 000 hired soldiers against Naples and con- tributed to the rapid spread of the disease over Europe after closure of that campaign. The infected soldiers returned to their homelands and brought syphilis with them. In Holland, syphilis was very likely introduced by the Spanish fleet who delivered, in 1496, the bride of Philip of Habsburg. About 24 000 spanish seamen stayed during that winter in the island of Walcheren in the province of Zeeland (Sealand) and experienced an outbreak of syphilis. In those days syphilis was nicknamed after your enemies. Although England and Holland fought four sea wars, the Dutch used to call syphilis the Spanish disease or the Spanish pox, and not the English disease. On the other hand the English decided to refer to French disease and not the Dutch disease. The STD character of syphilis was already recognised in those days: the condition was called disease from Venus and was distinguished from wounds due to fighting which were called a disease from Mars. STD and reproduction The awareness of the significance of STD for the form and function of the reproductive organs, especially for women, has taken a long time and is not complete even now. The importance of the fallopian tubes for the reproductive process was discovered over 400 years ago. The first accurate description of the human oviduct is credited to Gabriele Fallopio in his Observationes Anatomicae, published in Venice in 1561. The Dutchman, Reinier de Graaf from Delft was probably the first to illustrate the sequelae of infection of the fal- lopian tubes. He published an illustration of a distally closed tube entitled Oviductus Extremitas Praeter Natura Clausa in his De Mulerum Organis from 1672. The aetiology of closed tubes was unknown. Francois Mauriceau from France taught that pelvic inflammation resulted from an obstruc- tion of the lochia, while others indicated lacteal suppression and the resultant stasis of milk in the pelvis. All kinds of reasons have been offered: trauma, excessive intercourse, and even involuntary sexual abstinence in a single woman of strong passions, were listed among the causes of pelvic inflammatory dis- ease (PID). The relation between PID and the clinical entity of gonorrhoea was demonstrated for the first time by Bernutz and Goupil in 1857. In 99 autopsy examinations of PID cases they found in 28, or over 25%, an association with gonorrhoea. In general, real discoveries in medicine only provoke disbelief. Ten years later at the first meeting of the American Gynaecological Society the German gynaecologist Noeggerath stated that some 90% of sterile women were married to men who had suffered from gonorrhoea either pre- vious to, or during, their married life. He was simply not believed. The STD character of that important disease was not accepted by the audience. To quote only one of the many opponents on that occasion:... and if our Canadian ladies found out that their sterility was due to the former condition of their husbands, I do not know what would happen. The discovery of the gonococcus itself, by Albert Neisser in 1879, clarified the pathogenesis of a large pro- portion of PID cases in those times. Neisser even demonstrated the presence of his so called "micrococcus" in seven cases of acute ocular infection of the newborn: the proof of vertical transmission from the mother to her baby through the birth canal. So about 100 years ago the pathogenesis of the diseases from Venus was established as well as the possibility of vertical transmission of those diseases to the newborn. General awareness of the existence of STD is at least four centuries old, but the start of scientific The Harrison Lecture 440 o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://sti.b m j.co m / G e n ito u rin M e d : first p u b lish e d a s 1 0 .1 1 3 6 /sti.7 2 .6 .4 4 0 o n 1 D e ce m b e r 1 9 9 6 . D o w n lo a d e d fro m http://sti.bmj.com/ Blecker knowledge of STDs started only 100 years ago. STD awareness today The awareness of the significance of STD among specialists, such as gynaecologists, urologists and among the workers in primary care and even among the public may have increased somewhat recently. This is far from enough. A most important duty of the STD workers of today is how to raise the general STD interest and how to improve the STD knowledge among health care workers and the public. For example, gynaecologists (my own pro- fession) are not sufficiently aware that their speciality has much to do with infectious dis- eases and especially with STD. Genital can- cers and their pre-stages are beyond any doubt strongly related to HPV infections, a recog- nised STD. We must admit that the ideal anti viral-treatment modalities are not available yet and that we do not know exactly how to deal with the male sexual partners, but gynaecolo- gists anyhow should show more interest. Ectopic pregnancy, ruined internal genitals of the female, female tubal infertility, and possi- bly even male infertility as well, are simply due to STD infections like gonorrhoea, as already stated before, and Chlamydia trachomatis. Perinatal infections, like Syphilis, HIV infec- tion, Hepatitis and Chlamydia trachomatis infection are of extreme importance and are all STD's. Even premature labor and premature rupture of membranes and all the associated severe mortality, morbidity and high costs, are very likely related to infections, and in signifi- cant proportion possibly even to STDs. In primary care practice the two most important complaints among women are "vaginal discharge" and "abnormal uterine bleeding". Both complaints may be due to infections and even to STD's. For instance, the complaint of abnormal uterine bleeding among younger women should raise the suspi- cion for a Chlamydia trachomatis infection and should stimulate appropriate microbiological examinations. The examples of vulvo-vaginitis and PID from daily medical practices may clarify the position of STD awareness today. Vulvo-vaginitis The patient presenting with a vulvo-vaginitis is rather often (alas) only diagnosed by an exter- nal macroscopic examination. Consequently treatment is based on that simple "profes- sional" impression. We have to teach our pro- fessional colleagues again that an infection of the vulvar region is in the majority of cases a reactive vulvitis due to a primary infection of the vagina or even of the uterine cervix and the upper genital tract. We have to teach them again the simple habit to examine the vagina in those cases, to inspect the uterine cervix, to prepare a wet mount preparation for microscopy, to measure the pH of the vaginal fluid, to decide whether there is a fishy odor or not and to consider the need for cervical microbiology for N gonor- rhoeae and Chlamydia trachomatis. All these examinations are very simple and rather cheap. However one has to be prepared to per- form them, which means that all material must be at hand and not be looked for. In the latter case people will postpone their attempts to work according to the (simple) standards of care to the next case. More than likely it will never be done. The direct examinations of vaginal discharge, like pH, odor and microscopy of the wet mounts allow for a direct causative diagnosis in 80 percent of cases of vaginitis. A simple mono-diagnosis directs towards a simple mono-therapy, which is most efficient in these cases. Very likely monotherapy restores the normal vaginal milieu more quickly. However, even more important is the possibility that a mono-diag- nosis may clarify the presence of an STD such as trichomoniasis) or not and allows for an extended STD treatment: the counselling of the patient and the diagnosis and treatment of the sexual contacts. We really have to teach our colleagues in the profession and our col- leagues in primary care, that simple external macroscopic examination is never acceptable in case of vulvo-vaginitis. PID Another example is pelvic inflammatory dis- ease. In former days the classic picture of PID was thought to be due to gonorrhoea in the minority of cases, and unknown in the rest. The diagnosis was based on the clinical pre- sentation: abdominal pain and pain at both external- and internal examinations; besides fever and an elevated blood sedimentation rate. During the last decade or so we have recognised that Chlamydia trachomatis is an important cause of PID, that in PID cases Chlamydia is two to ten times more frequently present than gonorrhoea, that more than half of the PID cases do not show any clinical symptoms and that in symptomatic cases PID may present itself with right upper quadrant abdominal pain (the so-called Fitz-Hugh Curtis syndrome). Diagnostic tools for Chlamydia have only become widely available in the last ten years. It has recently become evident that these diag- nostic methods, such as the immunofluores- cence test and the ELISA test, may miss a significant amount of the Chlamydial infection cases as compared to the new DNA/RNA amplification methods. So once again we have to teach the profession a lot more: PID, the accepted main cause of tubal infertility is an STD in the overwhelming majority of cases, if not in all cases. Any primary treatment of PID must take the possibility of the presence of a Chlamydia infection into account. The sexual partners of the PID patient must be examined and treated, in the interest of the general pub- lic but also in the interest of the patient her- self, to prevent reinfection. Moreover, we must be aware of the exis- tence of subclinical cases of PID and therefore 441 o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://sti.b m j.co m / G e n ito u rin M e d : first p u b lish e d a s 1 0 .1 1 3 6 /sti.7 2 .6 .4 4 0 o n 1 D e ce m b e r 1 9 9 6 . D o w n lo a d e d fro m http://sti.bmj.com/ STD awareness today undertake diagnostic examinations for Chlamydia trachomatis in cases of abdominal pain, vaginal discharge and in cases of men- strual disorders, especially in younger women. STD care From these new developments, with respect to Chlamydia trachomatis, it is very obvious that it is not enough at all to teach our colleagues in the profession. Because of the subclinical PID cases and because of the asymptomatic carri- ers of Chlamydia trachomatis, the STD special- ists have the duty to inform the other doctors and health care workers. For instance, we must inform the internal medicine specialists about the Fitz-Hugh Curtis syndrome, the eye specialists about Chlamydial conjunctivitis, not just in the newborn, but the adolescents as well, and the STD character of that disease, the urologists about epididymitis, prostatitis and male infertility, the pediatricians about the possibility of Chlamydial infections in child- hood, the orthopaedics about Chlamydial arthritis and so on. We must also inform and cooperate with general practioners who see many more STD patients than we do, especially patients with less complaints and patients with an atypical presentation. In 1996 a campaign starts in Holland to inform primary care workers and other doctors about the different presentations of Chlamydial disease. On this occasion extra attention will be given to menstrual disorders in younger women. We must inform the government about the possibilities of prevention by information and screening of asymptomatics. The public too should be informed on matters relating to STDs. In fact STD care has to do with all aspects of medicine today, from general health to the adequate diagnosis of the individual patient. But STD care has also to do with the education of the public. We should inform and educate the public, especially the younger ones, the amateurs in love-making, like we all once were. We should inform them about the nature of STD, about the possibilities of con- traception and the prevention of STD (what we like to call "Double Dutch" in Holland), about the early signs of possible infections, like abnormal uterine bleeding in case of Chlamydia cervicitis and endometritis and offer them easy access to screening, and to diagnosis and treatment. We may even have the duty to create an open atmosphere for our children to debate all aspects of sexuality. STD Societies and Professional bodies have great importance in raising the knowledge and interest in STDs. A next and most essential step for these societies is to spread that knowl- edge to the medical profession as a whole and to the general public. This text is an adaption of the Harrison lec- ture, given at the MSSVD meeting of May 1996, in Edinburgh. 442 o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://sti.b m j.co m / G e n ito u rin M e d : first p u b lish e d a s 1 0 .1 1 3 6 /sti.7 2 .6 .4 4 0 o n 1 D e ce m b e r 1 9 9 6 . D o w n lo a d e d fro m http://sti.bmj.com/ work_3cwxrzp2mffr7orgld7wdirpt4 ---- The Reliability of Non-Cognitive Admissions Measures in Predicting Non-traditional Doctor of Pharmacy Student Performance O... American Journal of Pharmaceutical Education 2003; 67 (2) Article 64. TEACHERS TOPICS Biochemistry of the Water Soluble Vitamins: A Lecture for First Year Pharmacy Students Michael G. Bartlett, PhD Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, GA 30602-2352 Keywords: Biochemistry, vitamins This manuscript describes the lecture on vitamins contained in the core course entitled, “The Bio- chemical Basis of Drugs and Diseases” (Pharmacy 3050). In the first year, our curriculum is designed to focus on systems and diseases. As such, this course acts in concert with both the Anatomy & Physiology course and the Pathophysiology course to present an integrated view of human diseases and systems. The second year of our curriculum is focused on learning about drugs classes and the mechanism of action. The third year of the curriculum is focused on simulated patients, while the forth year of the curriculum the students are presented with real patients. The lecture on vitamins is the last topic of a course focused primarily on metabolism. Because many vitamins play major roles in metabolic cycles, this lecture allows for a brief review of much of the ma- terial covered throughout the course. Therefore, vitamin examples are primarily chosen to reinforce major metabolic cycles and also their role in human disease. There is more clinical information that is relevant to vitamins than what is presented in this lecture. However, since first year students in our curriculum have almost no knowledge of therapeutics, the focus of the lecture is on diseases and not clinical practice. INTRODUCTION Vitamins are a multibillion dollar industry.1 They are readily available to the public and are the focus of the most frequently asked questions to pharmacists. 2 Sur- prisingly, most pharmacy students receive little train- ing on the many roles of vitamins in nutrition.2 There- fore, this lecture attempts to not only reinforce fun- damental biochemical and metabolic pathways in the human body, but also to provide pharmacy students with practical information. The diet is a vast source of important nutrients. These nutrients include several important classes of biomolecules such as: (1) energy yielding components (carbohydrates, lipids, and proteins), (2) essential and nonessential amino acids, (3) essential fatty acids, (4) minerals, and (5) vitamins. Vitamins are organic sub- stances that must be provided by the diet either because they cannot be biosynthesized or the amount that is pro- vided through biosynthesis is inadequate for maintaining normal health. Vitamins are broadly divided into 2 classes based upon their hydrophobicity. The more hy- drophilic vitamins are termed the water-soluble vitamins and are composed of the B-complex vitamins and vita- min C. The more hydrophobic vitamins, referred to as the fat-soluble vitamins, are composed of Vitamins A, D, E, and K. This article focuses primarily on the water- soluble vitamins due to their greater role in the major metabolic cycles, which are the primary focus of this course. The normal North American diet is sufficient to pre- vent significant vitamin deficiencies and the related dis- eases associated with these deficiencies. However, there is increasing concern that slight vitamin deficiencies in a number of water-soluble vitamins (B1, B6, B12, folate and vitamin C) are risk factors for diseases such as Corresponding Author: Michael G. Bartlett, PhD. Mail- ing Address: Department of Pharmaceutical and Bio- medical Sciences, College of Pharmacy, University of Georgia, Athens, GA 30602-2352. Tel: (706) 542- 5390. Fax: (706) 542-5358. E-mail: bart- lett@rx.uga.edu. 1 American Journal of Pharmaceutical Education 2003; 67 (2) Article 64. Mild deficiencies of thiamin are sometimes ob- served in the elderly and in low-income groups on re- stricted diets. The earliest symptoms of thiamin defi- ciency are loss of appetite, constipation, and nausea. Other symptoms such as mental depression, peripheral neuropathy, irritability, and fatigue are related to the role of thiamin in maintaining a healthy nervous system. such as depression, cancer, cardiovascular disease, and neural tube defects. The prevalence of this slight vitamin deficiency is likely related to diet, since most of these vitamins are supplied by fruit and vegetable intake. A recent survey has shown that only 25% of the population meets their daily intake of 5 servings.3 Food preparation is another source of vitamin loss. For example, heating food for more than 2 hours causes more than a 10% loss of most water-soluble vitamins. Refrigeration, freezing, and reheating have all been shown to lead to further loss of vitamins. Ex- posure to light causes significant loss of riboflavin from foods and the combination of heating and light can almost completely remove this vitamin from food.4 The most common form of thiamin deficiency in the United States is alcoholic neuritis. Because alcoholics normally have a poor appetite, overall food consumption is low. In addition, alcoholics are predisposed to devel- oping nutritional deficiencies since alcohol is their pri- mary calorie source. Under the broad umbrella of alco- holic neuritis come two disorders, Wernicke’s Syn- drome and Korsakoff’s Psychosis.7 The symptoms of Wernicke’s Syndrome (ophthalmoplegia, nystagmus, and ataxia) respond quickly to administration of thia- min, whereas the more severe memory and learning dis- orders associated with Korsakoff’s Psychosis are refrac- tory to thiamin treatment. Thiamin (Vitamin B1) Thiamin functions in the body as thiamin pyrophosphate (TPP) an important enzyme co-factor.5 Thiamin reacts with adenosine triphosphate (ATP) to form thiamin pyrophosphate through a reaction medi- ated by the enzyme thiamin diphosphokinase. Follow- ing its production, TPP is incorporated into 2 impor- tant enzymes: pyruvate dehydrogenase and α- ketoglutarate dehydrogenase. Pyruvate dehydrogenase is part of a multi-enzyme complex that acts to convert pyruvate generated in glycolysis into acetyl-CoA for entry into the tricarboxylic acid (TCA) cycle. Thiamin pyrophosphate is also used as a co-factor for the en- zyme α-ketoglutarate dehydrogenase, which is a key point of regulation in the TCA cycle. α-Ketoglutarate dehydrogenase is involved in the conversion of α- ketoglutarate to succinyl CoA. In the case of both en- zymes, TPP assists in decarboxylation of a small ke- toacid. Riboflavin (Vitamin B2) Riboflavin functions in the body as an enzyme co- factor in many oxidation/reduction reactions and has a central role in energy production and cellular respira- tion. Riboflavin reacts with ATP to form flavin mono- nucleotide (FMN). Flavin mononucleotide then reacts with a second molecule of ATP to form a molecule of flavin adenine dinucleotide (FAD). Within cellular me- tabolism, enzymes such as succinyl dehydrogenase (TCA cycle), AcylCoA Dehydrogenase (β-Oxidation), and Glycerol-3-phosphate Dehydrogenase (Glycerol Phosphate Shuttle) use FAD as a cofactor. The enzyme NADH-CoEnzyme Q oxidoreductase (Complex I, Elec- tron Transport Chain) uses FMN as a co-factor. As en- zyme co-factors, FAD and FMN are able to function as electron acceptors. The addition of 2 electrons to FAD results in the formation of a molecule of FADH2, while the addition of 2 electrons to FMN causes the formation of a molecule of FMNH2. In addition to its uses in metabolism, thiamin may enhance circulation and blood formation. It is re- quired for maintenance of the nervous system and is used in the biosynthesis of the neurotransmitters ace- tylcholine and γ-hydroxybutyrate (GABA). Thiamin also is used in the production of hydrochloric acid in the stomach and, therefore, has a role in digestion. Riboflavin + ATP → FMN + 2e- ↔ FMNH2 FMN + ATP → FAD + 2e- ↔ FADH2 Thiamin is provided in the diet through most grains. A deficiency of thiamin is called beriberi and it is most often observed in Southeast Asia.6 The main staple of diet in this part of the world is rice, which does not provide dietary thiamin to as great an extent as other grains. The symptoms of beriberi include limb pain, muscle weakness, and low cardiac output. All symptoms are related to the diminished capacity of the major energy producing pathways that are de- pendent on TPP as a co-factor. The reduced forms of these enzyme co-factors can donate these electrons to return to their previous fully oxidized forms. It is this ability to act as a conduit for electron transfer reactions that makes FAD and FMN such important enzyme cofactors. Riboflavin is available from a wide variety of die- tary sources such as milk, cheese, meat, eggs, and cereal products. Symptoms associated with riboflavin defi- ciency include sore throat, dermatitis, anemia, neuropa- 2 American Journal of Pharmaceutical Education 2003; 67 (2) Article 64. thy, and cataract formation. Riboflavin deficiency is not normally observed in the United States; however, deficiency may be observed as part of a general case of malnutrition or in cases of chronic alcoholism.8 The conversion of riboflavin to FMN is required for absorption and transport into many tissues. The con- version has been shown to be inhibited by hypothy- roidism and the structurally similar medications chlorpromazine, adriamycin, quinacrine, tetracycline, and tricyclic antidepressants.9-12 Niacin (Vitamin B3) The vitamin niacin (nicotinic acid) and its struc- tural analog nicotinamide have identical function due to their facile interconversion in the body. Niacin is converted through a series of reactions to its active form nicotinamide adenine dinucleotide (NAD+). NAD+ can be converted to a reduced form NADH by gaining 2 electrons through a process similar to FAD reduction. NADH is produced in large quantities by the TCA cycle and β-Oxidation and to a lesser extent by glycolysis. Reduced NADH is returned to its oxi- dized form under normal cellular conditions by the electron transport chain. This newly reformed NAD+ can then return to other metabolic pathways to harvest more electrons. In the body the ratio of NAD+/NADH is approximately 1000 demonstrating the primary role of NAD+ in supporting cellular oxidation. NADH also can react with ATP to form NADPH. As opposed to the unphosphorylated form, the ratio of NADP+/NADPH is only 0.01. This ratio points to the role of NADPH in supporting reductive processes in the body. Niacin → NAD+ + 2e- ↔ NADH NADH + ATP ↔ NADPH + ADP Niacin can be found in foods such as meats, breads, and beans. Mild niacin deficiencies have simi- lar symptoms to those observed with riboflavin, which is not surprising due to the similar roles both of these vitamins play in biochemical reactions. Niacin deficiencies are occasionally observed in alcoholics, cases of general malnutrition, and in the elderly on restricted diets. A severe deficiency of niacin is known as pellagra, which is derived from the Italian phrase meaning rough skin. Pellagra is marked by dermatitis and also is notable for causing a blackening of the tongue. Early cases of pellagra were first ob- served in Europe shortly after the introduction of corn from the voyages of Christopher Columbus. In these cases, poor farmers who were raising corn as animal feed were particularly susceptible. Because niacin in corn is not bioavailable unless treated with a strong base such as lye, the farmers developed niacin deficien- cies. Europeans did not know this processing method until revealed to them by Native-Americans during the early colonial period of North America. However, the connection between pellagra and niacin was not known until the early 20th century. Pellagra was a significant health issue in the United States over the period from 1900-1940 resulting in over 100,000 deaths. Today most diets are supplemented with niacin through enriched flour, which receives its name because of the added nia- cin.13 Niacin can be administered in doses of 2g to 4g to causes a decrease in circulating levels of cholesterol and LDL. While the cholesterol lowering effects of niacin are desirable there are potential side effects from such large doses of this vitamin. The most immediate reaction observed from large doses of niacin is vasodilation re- sulting in flushing. Over time there may be a reduction in fatty acid mobilization causing a depletion of glyco- gen and lipid stores in muscle tissue. Long-term expo- sure may also elevate blood glucose and uric acid levels, suggesting increased risk for patients who are on the borderline for diseases such as diabetes and gout. Pro- longed use of high doses of niacin can lead to elevated levels of the serum enzymes alanine aminotransferase and aspartate aminotransferase, which may suggest liver damage. Pyridoxine (Vitamin B6) Pyridoxine is the precursor to the active enzyme co- factor pyridoxal phosphate (PLP). Pyridoxal phosphate is a critical co-factor for enzymes involved in reactions involving many amino acids. The N-terminus of the amino acid forms a covalent bond to PLP, allowing a wide variety of displacement reactions to occur at the alpha carbon. These include decarboxylations, transami- nations, and transfers of side chains. Pyridoxine, there- fore, plays a central role in the production of many neu- rotransmitters, such as serotonin, norepinephrine, and histamine. Pyridoxine also is important in the produc- tion of heme. The PLP co-factor in several enzymes is a therapeu- tic target due to the ability to form irreversible covalent bonds with agents containing a hydrazine moiety, such as carbidopa, isoniazid, and hydralazine.14 The combina- tion of L-Dopa and carbidopa is a widely used therapy that has a biochemical mechanism involving vitamin B6. The conversion of L-Dopa to dopamine is catalyzed by the PLP-dependent enzyme L-aromatic amino acid decarboxylase (LAAAD). L-DOPA → Dopamine 3 American Journal of Pharmaceutical Education 2003; 67 (2) Article 64. The enzyme LAAAD is present in both the gut and in the brain. This presents a problem because L- dopa is readily transported across the blood brain bar- rier while dopamine is not. Therefore, orally adminis- tered L-dopa is rendered ineffective in the gut by LAAAD. Co-administration of carbidopa resolves this dilemma by inactivating LAAAD in the gut. Like do- pamine, carbidopa cannot cross the blood brain bar- rier leaving LAAAD in the brain free to carry out the production of dopamine at the site of action. In addi- tion to hydrazine containing drugs, penicillamine, used in the treatment of Wilson’s disease, cystinuria, and rheumatoid arthritis reacts with and inactivates pyridoxal phosphate.15 Patients treated with penicil- lamine occasionally develop convulsions, which can be prevented by supplementation with vitamin B6. Pyridoxine is found in foods such as meats, breads, eggs, soybeans, and many vegetables. A defi- ciency in pyridoxine can cause facial lesions, depres- sion, peripheral neuropathy, and glossitis. The neuro- logical complications can be directly linked to the effects on neurotransmitter production. Mild pyridox- ine deficiencies are sometimes observed in young women taking oral contraceptives. Deficiencies have also been observed in patients with gasteroenteritis or Crohn’s Disease, presumably due to poor absorption. Mild deficiencies are of concern due to a correlation with an increased incidence of breast cancer and to the risk of coronary heart disease.16,17 Neurotoxicity has been noted with doses of vitamin B6 in excess of 500 mg/day. Cobalamin (Vitamin B12) Cobalamin is vital for cell growth and replication. Its major site of action is at the interface between the folic acid cycle and the active methyl cycle, where cobalamin is a co-factor for the enzyme homocysteine methyltransferase. This enzyme catalyzes the transfer of a methyl group from tetrahydrofolate to homocys- teine, forming the amino acid methionine. These 2 cycles impact many other pathways due to the large number of methylation reactions in the body, espe- cially nucleic acid biosynthesis and neurotransmitter biosynthesis. Cobalamin is found in meats and dairy products. Deficiencies are not common because the liver can store a 6-year supply of cobalamin. In addition, co- balamin is highly conserved by enterohepatic recircu- lation. Strict vegetarians (vegans) may take up to 20 to 30 years to develop a deficiency, whereas inade- quate absorption from the ileum due to ileitis or loss of a glycoprotein that complexes with cobalamin prior to absorption may take from 2 to 10 years to become symptomatic. The anesthetic nitrous oxide inactivates cobalamin and can cause patients with marginal serum levels to develop deficiencies within a week.19 While rare, deficiencies in vitamin B12 are severe and manifest in erythrocytes and nervous tissue. In erythrocytes, nu- cleic acid biosynthesis is slowed. This results in stem cells that are committed to development into erythro- cytes possessing twice their normal protein content but lacking the necessary nuclear material for proper cell division. The resulting anemia, termed megaloblastic anemia, can be quite severe. Cobalamin deficiency can also cause permanent damage to the nervous system. The results are swelling of neurons and demylination of nerve cells, followed by cell death. These progressive manifestations cause a wide range of neurological symp- toms including unsteadiness, decreased reflexes, pares- thesias of the extremities, and ultimately confusion, memory loss, hallucinations, and psychosis. The neuro- logical symptoms of cobalamin deficiency may be mis- taken for multiple sclerosis. In the elderly and in alco- holics, cobalamin deficiency should be considered as a possible cause of dementia even in the absence of ane- mia. The neurological symptoms associated with co- balamin deficiency are not directly related to irregulari- ties in the formation of erythrocytes.20 Folic Acid (Pteroylglutamic Acid) Folic acid is derived from the addition of a pteroyl group to the amino acid glutamate. Folic acid can be reduced to form tetrahydrofolate, which is an important acceptor of one-carbon units. Folic acid plays an impor- tant role in the conversion of homocysteine to methion- ine by providing the methyl to the vitamin B12 depend- ent methyl transferase. Therefore, folic acid levels have a strong influence on the endogenous concentration of homocysteine. Elevated levels of homocysteine are as- sociated with increased risk of coronary heart disease. Supplementation with folic acid has been shown to cor- rect plasma homocysteine levels and decrease the mor- bidity and mortality from atherosclerotic disease.21 Folic acid plays an important role in the biochemis- try of amino acids; it is critical for the interconversion of the amino acids serine and glycine and in histidine me- tabolism. Folic acid also is necessary for the biosynthe- sis of the nucleic acids thymidine, adenine, guanine, and inosine. Because of its role in amino acid and nucleic acid biosynthesis, folic acid supplementation during pregnancy has been shown to prevent most birth defects involving the brain and spinal cord, known as neural tube defects.22 4 American Journal of Pharmaceutical Education 2003; 67 (2) Article 64. Folic acid is found in organ meats such as liver, green leafy vegetables, yeast, and some fruits. Defi- ciencies in folic acid are most often observed with poor intake or alcoholism but are sometimes seen in pregnancy where there is an increased need for folic acid. The recommended daily allowance for pregnant women is at least twice that for nonpregnant women.23 Folic acid deficiencies can also be observed from reduced absorption due to diseases in the intes- tine. Additionally anticonvulsants, such as phenytoin, phenobarbital, and primidone appear to not only to inhibit folic acid absorption, but also to increase ca- tabolism.24 There is also concern that supplementation with folic acid may impact the effectiveness of these anticonvulsants. The most common effect of folic acid deficiency is megaloblastic anemia. The appearance of this type of anemia is identical to that observed with vitamin B12 deficiency due to the common pathway shared by the folic acid and the active methyl cycles. One major difference between folic acid deficiency and vitamin B12 deficiency is the absence of the neurological symptoms from lowered serum folic acid levels.25 Pantothenic Acid Pantothenic acid is one of the many B-complex vitamins. Once in the body, pantothenic acid com- bines with ADP and cysteamine to form coenzyme A (HSCoA). Coenzyme A is involved in a number of cellular pathways, most notably in transferring an ace- tyl unit from the pyruvate dehydrogenase complex or from β-oxidation to oxaloacetate in the TCA cycle. Coenzyme A is also involved in the biosynthesis of cholesterol, steroid hormones, fatty acids, and por- phyrins. Pantothenic acid derives its name from the Greek word meaning “from everywhere”, which re- flects its ubiquitous nature in foods. Deficiencies in pantothenic acid are difficult to achieve but result in neuromuscular degeneration.26 Biotin Biotin is an important co-factor for enzymes in- volved in carboxylation reactions. Biotin aids in these reactions by binding carbon dioxide. An important example of a biotin-containing enzyme is pyruvate carboxylase. This enzyme catalyzes the conversion of pyruvate to oxaloacetate as a preliminary step in glu- coneogenesis. Biotin is found in foods such as liver, egg yolks, milk, fish and nuts. Deficiencies in biotin result in dermatitis, glossitis, muscle pain and anorexia. Defi- ciency in biotin has been observed in patients ingest- ing raw eggs over a long period of time. Egg white con- tains avidin, a protein that binds biotin, strongly preventing its absorption from the intestine.27 Biotin deficiency was observed in early attempts at parenteral nutrition before proper vitamin supplementation became standard practice.28 Choline Choline has many important biochemical roles in the body. It is incorporated into the formation of leci- thin, an important structural phospholipid found most abundantly in mitochondrial membranes. It is also in- corporated into platelet-activating factor, an important signaling agent in the clotting cascade. Choline also af- fects lipid mobilization from the liver. However, its most important role is as a precursor for the neurotrans- mitter acetylcholine where it plays a critical role in mo- tor coordination. Choline is found in eggs, peanuts, and liver. Defi- ciency in choline has not been reported in humans. It is believed that daily needs for choline can be met through biosynthesis and diet. Carnitine Carnitine has an important role in the metabolism of fatty acids. Carnitine accepts and donates fatty acids to co-enzyme A. This is an equilibrium process facilitated by cytosolic and mitochondrial enzymes known as car- nitine acyl transferases. The attachment of fatty acids to carnitine is critical for their transport from the cytosol to the mitochondria, where they are later metabolized through β-oxidation. Carnitine is found abundantly in meats and dairy products. Carnitine deficiency is not normally observed in adults unless it is caused by an inherited genetic dis- order related to its transport or biosynthesis. Carnitine deficiency causes the storage of lipids in muscle tissue resulting in functional abnormalities in both cardiac and skeletal muscles. However, carnitine deficiencies are not uncommon in preterm or low birth weight infants. These infants generally respond to supplements of carnitine as well as changing to a low-fat, high-carbohydrate diet.29 Ascorbic Acid (Vitamin C) Ascorbic acid acts as an enzyme co-factor for 2 ma- jor biochemical processes. It is important for many hy- droxylation reactions, especially those involved in the posttranslational hydroxylation of the amino acid proline in the formation of the structural protein colla- gen. In the gut, vitamin C is involved in the reduction of iron (III) to iron (II), allowing iron to be absorbed into the bloodstream. 5 American Journal of Pharmaceutical Education 2003; 67 (2) Article 64. Table 1. Student perception of the most significant part of the lecture, most inter- esting part of the lecture, and the topic they would like to have greater coverage. Response Percentage Significance (N=28) Biochemical function of vitamins 61% Vitamin deficiencies 18% Sources of vitamins 11% Interesting (N=28) Biotin and raw eggs 18% Scurvy and “Limeys” 18% Alcoholism and vitamins 14% Increase Focus (N=27) Folic acid deficiency 8% Alcoholism and vitamin deficiencies 8% Drug interactions and vitamins 8% Humans are one of the few organisms that are in- capable of biosynthesizing ascorbic acid. As such they are highly dependent on obtaining it from their diet. Vitamin C is found in citrus fruits, tomatoes, strawberries, and potatoes. During the Age of Explo- ration, British sailors were given the nickname “lim- eys” due to the barrels of limes that were used on long voyages to supply vitamin C to the crew. The sailors were trying to avoid a deficiency in ascorbic acid known as scurvy.30 The symptoms of scurvy are re- lated to inhibited synthesis of collagen. These effects include failure of wounds to heal, defects in tooth formation, and capillary leakage. Anemia caused from failure to adequately absorb iron is also common.31 Several factors have been shown to lower serum vi- tamin C levels including smoking, oral contracep- tives, and the use of aspirin.32-34 Patients exposed to any of these conditions long-term should consider taking a vitamin C supplement. However, the use of high doses of vitamin C, a theory popularized by No- bel Laureate Linus Pauling, has not been shown to provide any medical benefit.35 The use of high doses of vitamin C has been shown to cause nausea, diar- rhea, and lead to the formation of oxalate kidney stones.18,35 Student Perception of Lecture Student opinions were obtained using minute pa- pers. Minute papers are given to a group of 25-30 stu- dents following each lecture in this course.36 From the results of the minute papers in Table 1, the student’s perception of the lecture is apparent. The students believe that the most significant material in the lecture was the discussion on the major biochemical functions of the vitamins. This is consistent with the intent of the instructor. The students also felt that understanding vi- tamin deficiencies and the sources of the various vita- mins was important. The students were asked what they found interesting about the lecture and not surprisingly they selected various stories as their favorite points. They especially liked the link between biotin, avidin, and eggs, the nautical history of scurvy resulting in the nickname “Limeys” being given to British sailors, and understanding the role of appetite suppression in alco- holism and general vitamin deficiencies. Over the years, students have commented that they enjoy having inter- esting health related facts to aid them in retaining and understanding the utility of biochemical information. Vitamins provide an enormous number of examples that can be used. Finally, the students were asked to recom- mend areas that could have increased focus in the future. In general these comments fall into 2 catagories. The students are either confused and would like more information to more fully understand the topic, or they are genuinely interested and would like to know more. In this case, 71% of the student responded that they did not see anything else to add. There were a few sugges- tions for adding additional information on folic acid deficiency, alcoholism, and drug-vitamin interactions. This text incorporates many of these suggestions with the inclusion of the link between folic acid and neural tube defects, discussions of alcoholism throughout the lecture rather than being highly focused around thiamin, and drug interactions involving the vitamins pyridoxine, folic acid, and riboflavin. 6 American Journal of Pharmaceutical Education 2003; 67 (2) Article 64. CONCLUSIONS Questions concerning the use of vitamins are common. Vitamins have important roles in many of the major metabolic pathways in the human body. In addition, drug interactions with vitamin and diseases involving vitamin deficiencies are important topics for pharmacy curricula. An understanding of the func- tional roles of vitamins can contribute to improved understanding of general biochemistry and help pharmacy students become better prepared for their roles as health care educators. REFERENCES 1. Muth MK, Nardinelli C, Beach RH. The marketplace for die- tary supplements: recent studies. Drug Inf J. 2001; 35:973-83. 2. Joseph CK. Nutritional supplements: amino acids and their derivatives. Am J Pharm Educ. 2002; 66:157-64. 3. Flood A, Schatzkin A. Colorectal cancer: does it matter if you eat your fruits and vegetables? J Nutl Cancer Inst. 2000; 92:1706- 7. 4. Williams PG. Vitamin retention in cook/chill and cook/hot-hold hospital services. J Am Diet Assoc. 1996; 96:490-8. 5. Schenk G, Duggleby RG, Nixon PF. Properties and functions of the thiamin diphosphate dependent enzyme transketolase. Int J Biochem Cell Biol. 1998; 30:1297-1318. 6. Krishna S, Taylor AM, Supanaranond W, Pukrittayakamee S, ter Kuile F, Tawfiq KM, Holloway PAH, White NJ. Thiamine deficiency and malaria in adults from Southeast Asia. Lancet. 1999; 353:546-9. 7. Cook CCH, Hallwood PM, Thomson AD. B vitamin deficiency and neuropsychiatric syndromes in alcohol misuse. Alcohol Alco- holism. 1998; 33:317-36. 8. Hoyumpa AM. Mechanisms of vitamin deficiencies in alcohol- ism. Alcoholism Clin Exper Res. 1986; 10:573-81. 9. Pelliccione N, Pinto J, Huang YP, Rivlin RS. Accelerated de- velopment of riboflavin deficiency by treatment with chlorpro- mazine. Biochem Pharmacol. 1983; 32:2949-53. 10. Ogura R, Ueta H, Hino Y, Hidaka T, Sugiyama M. Riboflavin deficiency caused by treatment with adriamycin. J Nutr Sci Vita- minol. 1991; 37:473-7. 11. Dutta P, Raiczyk GB, Pinto J, Rivlin RS. Inhibition of ribofla- vin metabolism by tetracycline and quinacrine — drugs with an- timalarial properties. Clin Res. 1986; 34:A636-A636. 12. Pinto J, Huang YP, Rivlin RS. Inhibition of riboflavin metabo- lism by imipramine and amitriptyline in rats. Federation Proceed- ings. 1981; 40:916. 13. Rajakumar K. Pellagra in the United States: a historical per- spective. Southern Med J. 2000; 93:272-7. 14. Koller WC, Rueda MC. Mechanism of action of dopaminergic agents in Parkinson’s disease. Neurology S6. 1998; 50:S11-S14. 15. Levy MD. Pyridoxine and Penicillamine. Ann Intern Med. 1982; 96:125. 16. Kirksey A, Keaton K, Abernathy RP, Greger JL. Vitamin B6 nutritional status of a group of female adolescents. Am J Clin Nutr. 1978; 31:946-54. 17. Bender DA. Vitamin B6: requirements and recommendations. Eur J Clin Nutr. 1989; 43:289-309. 18. Ziegler EE. Present Knowledge in Nutrition. Washington, DC: International Life Sciences Institute; 1996. 19. Mayall M. Vitamin B12 deficiency and nitrous oxide. Lancet. 1999; 353:1529. 20. Carmel R. Cobalamin, the stomach, and aging. Am J Clin Nutr. 1997; 66:750-9. 21. Ward M. Homocysteine, folate, and cardiovascular disease. Int J Vit Nutr Res. 2001; 71:173-8. 22. Botto LD, Moore CA, Khoury MJ, Erickson JD. Neural tube defects. New Engl J Med. 1999; 341:1509-19. 23. National Academy of Sciences. Dietary Reference Intakes. Washington, DC: National Academy Press; 1998. 24. Hernandez-Dias S, Werler MM, Walker MM, Mitchell AA. New Engl J Med. 2000; 343:1608-14. 25. Chan LN. Drug-nutrient interaction in clinical nutrition. Curr Opin Clin Nutr. 2002; 5:327-32. 26. Smith CM, Song WO. Comparative nutrition of pantothenic acid J Nutr Biochem. 1996; 7:312-21. 27. Forbes GM, Forbes A. Micronutrient status in patients receiving home parenteral nutrition. Nutrition. 1997; 13:941-4. 28. Baugh CM, Malone JH, Butterwo CE. Human biotin deficiency: a case history of biotin deficiency induced by raw egg consumption in a cirrhotic patient. Am J Clin Nutr. 1968; 21:173-82. 29. Pons R, Devivo DC. Primary and secondary carnitine deficiency syndromes. J Child Neurol. 1995; 10(Suppl):2S8-2S24. 30. Barker JA. Lind and Limeys: a brief early history of scurvy and the search for its cure in the 18th century. J Biol Educ. 1992; 26:45- 53. 31. Ural AU. Anemia related to ascorbic acid deficiency. Am J He- matol. 1997; 56:69. 32. Cross CE, Traber M, Eiserich J, van der Vliet A. Micronutrient antioxidents and smoking. Brit Med Bull. 1999; 55:691-704. 33. Shenfield GM. Oral-contraceptives: are drug interactions of clinical significance. Drug Safety. 1993; 9:21-37. 34. Loh HS, Wilson CWM. Interactions of aspirin and ascorbic acid in normal men. J Clin Pharmacol. 1975; 15:36-45. 35. Auer BL, Auer D, Rodgers AL. Relative hyperoxaluria, crystallu- ria, and haematuria after megadose ingestion of vitamin C. Eur J Clin Invest. 1998; 28:695-700. 36. Bartlett MG, Morrow KA. Method for assessing course knowl- edge in a large classroom environment: an improved version of the minute paper. Am J Pharm Ed. 2001; 65:264-8. 7 TEACHERS TOPICS Biochemistry of the Water Soluble Vitamins: A Lecture for First Year Pharmacy Students Response work_3drxc3jfxngotjduhpdieb7nrq ---- AMS volume 27 issue 2 Cover and Back matter LOUISIANA STATE UNIVERSITY PRESS Abraham Lincoln, Public Speaker Waldo W. Braden 119 pp, £7.95 pb Desegregating the Altar The Josephites and the Struggle for Black Priests, 1871-1960 Stephen J. Ochs 500 pp, £15.95 pb Zachary Taylor Soldier, Planter, Statesman of the Old Southwest K. Jack Bauer 348 pp, £13.95 pb John C. Calhoun and the Price of Union A Biography John Niven 367 pp, £11.95 pb Antebellum Natchez D. 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C L A R K South Pacific and American Remembering; or, " J o s h , We're G o i n g to Buy This Son o f a B i t c h ! " 207 P H I l I P I ) . B E I D L E R T h e I^ong Last G o o d b y e : Control and Resistance in the Work o f William Burroughs 223 D A V I D A Y 1 R S N o t e s a n d C o m m e n t A Response to Waiden 2 3 7 J I M L E W I S Glenn H. Wakefield ( 1 8 7 3 - 1 9 3 9 : - ) , alias " H a m B a n n i s t e r " : Five Poems by the Grifter Poet 2 4 4 J O H N H A N N I R S R e v i e w E s s a y Michael K д m m e n s Commemoration o f the Americanist Tradition 249 P E T I R L I N G R e v i e w s 255s CAMBRIDGE UNIVERSITY PRESS 0021 -8758(199308)27:2:1 -H terms of use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0021875800031492 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:18, subject to the Cambridge Core https://www.cambridge.org/core/terms https://doi.org/10.1017/S0021875800031492 https://www.cambridge.org/core work_3fapasrmcfdmzizzkvnteilhi4 ---- 354 BOOK REVIEWS feeding ecology that might also explain their hitherto- unexplained dark plumage? Tickell does not speculate on this point. Nor does he set out avenues of future research. Given that the age at which individuals of a species start to breed varies so much, and has been declining in some declining populations, it would be fascinating, if difficult, to understand more of the basis for these inter-individual differences. Now that Theresa Burg's unpublished doctoral work in the Department of Zoology at Cambridge has established more extra-pair paternity in wandering albatrosses Diomedea exulans than hitherto realised, there may be scope for more behavioural ecology studies. And the flood of information from transmitters that monitor the birds' positions and physiological states can only increase. The challenge is to ensure that the data are used to address focused questions. How does Albatrosses compare with the opposition? Robertson and Gales (1998) edited a book that is substantially devoted to the impact of longlining on albatrosses. It therefore does not begin to compare with TickelPs book as an all-round source of information on albatross biology. John Warham's (1990, 1996) two excellent volumes were largely written before the advent of satellite tracking permitted wonderful advances in the understanding of albatrosses at sea. Thus the clear message is that, if you are seriously interested in albatrosses, it would be a sin not to obtain Tickell's Albatrosses. How lucky these birds are to have been served by such a dedicated author. (M. de L. Brooke, Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ.) References Robertson, C.J.R., and G.B. Nunn. 1998. Towards a new taxonomy for albatrosses. In: Robertson, G., and R. Gales (editors). Albatross biology and conservation. Chipping Norton: Surrey Beatty: 13-19. Robertson, G., and R. Gales (editors). 1998. Albatross biology and conservation. Chipping Norton: Surrey Beatty. Warham, J. 1990. The petrels: their ecology and breeding systems. London: Academic Press. Warham, J. 1996. The behaviour, population biology and physiology of the petrels. London: Academic Press. RAVEN'S SAGA: AN ARCTIC ODYSSEY. Peter Schledermann. 2000. Calgary: Corvus Press. 347 p, soft cover. 0-9687088-0-3. Cdn$15.00; US$12.00. Raven's saga is a significant departure from Peter Schledermann's previous work, which had been situated more narrowly within the domain of the social sciences, especially archaeology. Here, Schledermann shifts to the realm of fiction, informed by the considerable knowledge he has accumulated over the years as a research social scientist, in order to reconstruct a long-past world. At a time when universities in Canada pay great lip service to the importance of interdisciplinary studies, Schledermann's new book truly embraces that integrated notion so elusive to the fragmented approaches of the academy. Schleder- mann draws on his vast professional knowledge of Arctic archaeology and ethnography, as well as his personal interests in sailing and Scandinavian cultural history, to create a piece of fiction that is solidly situated in an historical setting. This is undoubtedly a piece of historical fiction. And historical fiction should be distinguished from fiction that merely uses the historical past as its setting. In many ways, historical fiction is like science fiction: both are imagina- tive accounts attempting to understand something that exists outside the realm of the imagination. Science fiction, at its best, grows out of some subtle principle of science, exploring it in the realm of the imagination. In H.G. Wells' The war of the worlds, for example, the invasion of Earth by the Martians is premised on the scientific understanding that Mars, because of its greater distance from the Sun, would have cooled sooner than Earth, thus allowing the evolutionary process of life to begin long before it was possible on the much hotter Earth. Accordingly, the environment of Mars would have gener- ated more highly evolved forms of life than were present on Earth at the time the book was set. And it is the medical understanding of how organisms build natural immunities to familiar viruses and bacteria that Wells ultimately uses to defeat the Martians upon their invasion of Earth. Raven's saga operates in much the same way. Both books construct an imagined world, although one soundly premised on the scientific understanding of the tactile world in which we live. But while The war of the worlds launches forward into the imagined future, Raven's saga reaches backwards into the distant past. Schledermann's created world of the past, like Wells' imagined world of the future, is solidly based on scientific data that can be verified and substantiated. The imagination comes into play in Schledermann's attempt to account for how those factual, historical details could have occurred. Where organic and inorganic evolution provide the scientific thrust to Wells' fiction, the principles of archaeology inform Schledermann's book. In 1978 and 1982, Schledermann and his colleagues discovered a number of Norse artifacts during archaeo- logical excavations in the high Arctic. Rivets from Viking ships, chain-mail of the variety worn during the Crusades, a Norse carpenter's plane, a knife blade, and several other items were found in the ruins of an Inuit winter house on an island off the central east coast of Ellesmere Island. The house, according to radiocarbon technology, had been occupied sometime between 1250 and 1300 AD. These facts are grounded in the sound empirical observations of sophisticated archaeological research. But they are only the beginning — the point of embarkation, if you will — from which the imaginative journey that is Raven's saga begins. In Schledermann's imaginative reconstruction, an exploratory expedition sets out from the southern tip of Greenland around 1278 and travels up Greenland's west coast beyond modern Thule to Skraeling Island, one of numerous islands midway up the east coast of Ellesmere BOOK REVIEWS 355 Island. While the expedition is underway, and, to a great extent, one of the factors prompting it, a colonizing power struggle takes place in the Norse settlement of Vesterbygd on the southern tip of Greenland. Self-serving machinations by ambitious priests in the Catholic Church and crippling trade restrictions imposed by King Magnus of Norway, who has proclaimed sovereignty over Greenland, seriously threaten the peaceful way of life in the seemingly once- remote frontier of Vesterbygd. The action of the novel shifts back and forth between these two venues. The story of the northern expedition is filled with Boy's Own Magazine variety of adventure, as the small party encounters the natural forces of sea ice, polar bears, and walrus, and the cultural dynamic of first contacts between Europeans and Inuit. Back in the settlements, the story is more complex, with Schledermann drawing on his extensive knowledge of the politics and history of Greenland, Iceland, and Markland (modern Labrador) and their role as the European frontiers of their day. The characterisation throughout is polarised, typical of the romance. The protagonist, Tore Ey vindsson, is a stock heroic figure — young, adventurous, and physically at- tractive to women. He leads the expedition to the coast of Ellesmere Island and returns to marry the chieftain's daughter. To reveal this resolution of the plot will not spoil the book, because no reader would ever imagine a different conclusion. The psychological detail of individual charac- ters counts for little here. Rather, Schledermann has focused the reader's attention on a sense of the setting — both temporal and spatial — in which the action unfolds. This sense of an historical setting is certainly where the book shines. Educated people have long doubted the accuracy of that public-school rhyme concerning the Eu- ropean discovery of North America: 'In fourteen hundred and ninety-two, Columbus sailed the ocean blue.' We have heard too many vague accounts of earlier European contact with North America: fleeting textbook allusions to Leif Ericsson, rumoured work by Helge Ingstad at L'Anse aux Meadows, the Viking grave discovered in Farley Mowat's Lost in the Barrens. But few of us have a solid image of Norse commerce in the New World to match that solidly ingrained mental icon of Nina, Pinta, and Santa Maria sailing into the Caribbean Sea under Christopher Columbus' command. Nor do most of us have an under- standing of European politics in the thirteenth century to match our general grasp of Europe at the beginning of the Renaissance. Raven's saga provides much of that under- standing, as well as a better sense of Inuit culture during the same period. One learns about the important rituals associated with the solstice, the social and economic structure of Norse and Inuit societies, and the practicalities of rope-making, boat-building, food preparation, and house construction. One has an opportunity to glimpse the Crusades as something perpetuated by those who profit from military conflict, and not merely as yet another manifestation of blind religious fanaticism. One is pro- vided with a window through which to observe the eco- nomic hardship that a frontier society of hunters and pastoralists must endure when the Pope and the Norwegian king make sweeping decisions from afar. Schledermann's historical reconstruction also probes into the difficulties encountered when traditional cultures come into contact with new cultures. Some of the mem- bers of the northern expedition to Skraeling Island return to Vesterbygd, bringing with them improved skills and techniques learned from the Inuit. But those better meth- ods are not always accepted, simply because they are new and unfamiliar. Other expedition members choose never to return to their Norse roots, preferring the Inuit culture that has embraced them. Although the setting of Raven's saga is more than eight centuries in the past, there is much of relevance here to modern Canadian society. This is especially true in matters related to northern cultures and the effect on them of more southerly populations. (Richard C. Davis, Department of English, University of Calgary, 2500 University Drive NW, Calgary, Alberta T2N 1N4, Canada.) LEADING AT THE EDGE: LEADERSHIP LES- SONS FROM THE EXTRAORDINARY SAGA OF SHACKLETON'S ANTARCTIC EXPEDITION. Dennis N.T. Perkins, with Margaret P. Holtman, Paul R. Kessler, and Catherine McCarthy. 2000. New York: American Management Association, xx + 268 p, hard cover. ISBN 0-8144-0543-6. $24.95. This book forms part of the contemporary oeuvre based around Sir Ernest Shackleton. The qualities and behaviour exhibited by Shackleton are crafted into a template for identifying and developing the performance and skills of leadership. Another recent book exploring this theme is Shackleton's way, by Morrell and Capparell (2001a), and an article by these authors appears in the March 2001 issue of Director, the magazine for the Institute of Directors (Morrell and Capparell 2001b). In Apsley Cherry-Garrard's first edition of The worst journey in the world (putatively the best exploration book of the twentieth century), he comments on Antarctic lead- ership styles: 'For a joint science and geographical piece of organisation, give me Scott; for a Winter Journey, Wilson; for a dash to the Pole and nothing else, Amundsen; and if I am in a devil of a hole and want to get out of it, give me Shackleton every time' (page viii). Since that time the legend of Shackleton has continued to grow, the last few years having seen a glut of exhibitions, TV and other visual media programmes, and newspaper and magazine articles on arguably this most of charismatic of all Antarctic explorers. Much of the current interest may stem from the paucity of present-day 'real heroes.' Although space exploration provides a genuine frontier, the public are, ineluctably, drawn to the raw confrontation of man with the elements epitomised by the expeditions to Antarctica during the first two decades of the last century. Shackleton's Imperial Trans-Antarctic Expedition of 1914-17 has con- tinually captured imaginations, not for what was achieved in exploration terms, but for the sheer determination and audacity of Shackleton's team to survive against incalcu- work_3lnffhuqpbcbplnpjjylltvlwu ---- wp-p1m-39.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-39.ebi.ac.uk no 218194864 Params is empty 218194864 exception Params is empty 2021/04/06-02:09:19 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. Message ID: 218194864 (wp-p1m-39.ebi.ac.uk) Time: 2021/04/06 02:09:19 If you need further help, please send an email to PMC. Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_3ncqxyvnjrgydnabqeto7z56cm ---- [PDF] Editorial: Save Research---Abandon the Case Method of Teaching | Semantic Scholar Skip to search formSkip to main content> Semantic Scholar's Logo Search Sign InCreate Free Account You are currently offline. Some features of the site may not work correctly. DOI:10.1287/MKSC.1060.0202 Corpus ID: 42940113Editorial: Save Research---Abandon the Case Method of Teaching @article{Shugan2006EditorialSR, title={Editorial: Save Research---Abandon the Case Method of Teaching}, author={Steven M. Shugan}, journal={Marketing Science}, year={2006}, volume={25}, pages={109-115} } Steven M. Shugan Published 2006 Psychology Marketing Science The case method of teaching and the corresponding Socratic Method predate the discovery of the scientific method for advancing knowledge and problem solving. The case method applies known principles e.g., laws to specific situations while the scientific method focuses on discovering principles. Although the case method might be effective at teaching leadership and persuasion skills, it can lack the spirit of inquiry and the worship of the truth associated with the scientific method. Moreover… Expand View via Publisher bear.warrington.ufl.edu Save to Library Create Alert Cite Launch Research Feed Share This Paper 59 CitationsHighly Influential Citations 7 Background Citations 23 Methods Citations 14 Results Citations 2 View All 59 Citations Citation Type Citation Type All Types Cites Results Cites Methods Cites Background Has PDF Publication Type Author More Filters More Filters Filters Sort by Relevance Sort by Most Influenced Papers Sort by Citation Count Sort by Recency Course Research: Using the Case Method to Build and Teach Management Theory Clayton M. Christensen, Paul R. Carule Sociology 2009 131 PDF Save Alert Research Feed Exploration of the efficacy of the case method of teaching M. Reed, Rochelle Reed Brunson Psychology 2018 2 Save Alert Research Feed The Perceived Influence of Case Method on Students’ Performance and Critical Thinking in Business Studies Xhimi Hysa, Luca Carrubbo, Armeno Sadiku, Irma Gjana, Nensi Hazizaj Psychology 2020 View 2 excerpts, cites background and methods Save Alert Research Feed Connecting with Reality: Using Mini-Case Study Approach to Facilitate and Assess Student Learning Lucy Xiaolu Wang Sociology 2017 View 2 excerpts, cites background Save Alert Research Feed The Role of Theoretical Breadth and Student Engagement in the Use of Case Methods in Marketing Pedagogy S. Sudhir, Anandakuttan B. Unnithan Sociology 2018 Highly Influenced PDF View 6 excerpts, cites methods and background Save Alert Research Feed Can civility be taught to Latin-American MBAs? Implications of case-method use for the development of civic behaviour in managerial education María Helena Jaén, Ezequiel Reficco, M. Ossa Sociology 2014 3 Save Alert Research Feed Transforming research case studies into teaching cases P. Strach, A. Everett Sociology 2008 18 View 1 excerpt, cites background Save Alert Research Feed Case-method teaching: advantages and disadvantages in organizational training Naghi Radi Afsouran, Morteza Charkhabi, S. Siadat, R. Hoveida, H. Oreyzi, G. Thornton Computer Science 2018 3 Save Alert Research Feed Case teaching in economics: History, practice and evidence G. Volpe Economics, Computer Science 2015 9 PDF View 2 excerpts Save Alert Research Feed International Business Education at the Interface: The Raw Case Study Method Y. Shi, S. Dow Sociology 2019 2 Highly Influenced View 4 excerpts, cites background Save Alert Research Feed ... 1 2 3 4 5 ... References SHOWING 1-10 OF 67 REFERENCES SORT BYRelevance Most Influenced Papers Recency The case method – does learning theory matter? A. Mumford Psychology 2005 13 Save Alert Research Feed The Socratic method in the introductory PR course: An alternative pedagogy M. Parkinson, Daradirek Ekachai Psychology 2002 35 Save Alert Research Feed Editorial: Consulting, Research, and Consulting Research Steven M. Shugan Sociology 2004 34 PDF Save Alert Research Feed Should Case Materials Precede or Follow Lectures F. Phillips, G. Vaidyanathan Psychology 2004 16 Save Alert Research Feed The use of case studies in management training and development. Part 1 W. Rees, C. Porter Psychology 2002 39 Save Alert Research Feed Those Who Understand: Knowledge Growth in Teaching L. Shulman Psychology 1986 11,143 PDF Save Alert Research Feed Case Writing Reconsidered Craig C. Lundberg, P. Rainsford, J. Shay, C. Young Sociology 2001 51 View 2 excerpts, references methods and background Save Alert Research Feed The Effect of the Case Method on Tolerance for Ambiguity Kevin Banning Psychology 2003 82 View 2 excerpts, references background Save Alert Research Feed A Case Method for Teaching Statistics W. Carlson Economics 1999 37 Save Alert Research Feed The future of the business school: Knowledge challenges and opportunities K. Starkey, S. Tempest Sociology 2005 120 Save Alert Research Feed ... 1 2 3 4 5 ... Related Papers Abstract 59 Citations 67 References Related Papers Stay Connected With Semantic Scholar Sign Up About Semantic Scholar Semantic Scholar is a free, AI-powered research tool for scientific literature, based at the Allen Institute for AI. Learn More → Resources DatasetsSupp.aiAPIOpen Corpus Organization About UsResearchPublishing PartnersData Partners   FAQContact Proudly built by AI2 with the help of our Collaborators Terms of Service•Privacy Policy The Allen Institute for AI By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License ACCEPT & CONTINUE work_3pqojd3xmzgvrcdnupfw2jnmrm ---- Microsoft Word - Man on the Moon.docx Man on the Moon A short, critical analysis of Neil Armstrong's photograph from the Apollo 11 mission "...a wider problematic of human- nonhuman relations, and raise the politico-ethical question of human responsibility in a world in which the agency of the majority of actants— such as wind, meteorites, rain, or earthquakes—goes beyond that of human decision or will, even if it may be influenced by human action. The question of human responsibility in the universe, in which we are quintessentially entangled on both a cellular and a cosmic level (with all of us being “made of starstuff,” as Carl Sagan remarked in his documentary TV series Cosmos), is an important one." (Zylinska, 2017, p.58) Image 1 The Moon☽; our planet's only natural satellite shadowing Earth and serving as its sidekick, like the biblical Eve to Adam, is again subject of popular discourse both within and beyond astronomical research, as the first Moon landing called the Apollo 11 project by NASA is celebrating its 50th anniversary in 2019. This paramount event of the history of humankind was carried out on the 20th July, 1969 by two American astronauts, Neil A. Armstrong and Edwin E. "Buzz" Aldrin Jr. It was a success for scientific research, space engineering, political relations, and social progress. Despite the controversies around the legitimacy of the Moon landing, that have been debated on for decades, there is a substantial amount of photographic material documenting some significant momentums of the mission. One of these, according to the journalist Jonathan Jones, can be perceived as "one of the revolutionary artistic masterpieces of the 20th century" (Jones, 2019). The photo in question is Armstrong's double-horizon portrait of his colleague, Aldrin, bearing the title: A triumph of human consciousness in an otherwise mindless universe (Image 1). In his article for The Guardian ("The greatest photos ever? Why the moon landing shots are artistic masterpieces"), Jones argues, amongst other things, that the significance of this portrait is in its all- encompassing power. In his unisex spacesuit and faceless figure Aldrin becomes a symbol for all men and women on Earth, while the uncanny landscape surrounding him is the object of discovery, representing everything non-human, but potentially governed by our species. (Jones, 2019) Even though he is described by Jones as being genderless and embodying each one of us, my counterargument is that the portrait is very much a symbol of hegemonic masculinity. Already indicated by the title of the photo, the "triumph" over the natural spheres, also perceived as an act of homogenous control, marks the affinity of the human species in relation to the rest of the universe. The ultimate heroic mission of bringing rational consciousness to what is deemed primal and unpredictable, might ring a familiar bell for those engaged in critical gender theory, as it is clearly derived from the same source as the disabling of feminity in our virile world. This question, however, might remain invisible to the masters of the cosmos, who can freely move around spaces, without having to encounter their own limitations of privilege. For the following six lunar journeys where a total of twelve astronauts have set their feet on the Moon, not one of them were women or non-binary individuals. The naming of the missions is already a telling choice; Apollo in Greek mythology is the male deity of the sun, light, knowledge, order and angriculture, along many other things, but essentially the epitome of physical superioirity and moral virtue. Aldrin and Armstrong, the two pivotal figures of the Apollo 11 mission, carry this legacy with them together with the weight of their cultural backgrounds. The portait taken by Armstrong is a complex one, both visually and conceptually. It was exposed with a specially made Hasselblad camera, which, together with the photographer and the rest of the technical equipment, are all reflected on the surface of Aldrin's space helmet. The image has been composed so that the scale of the Moon in relation to the size of the portrayed person is distorted, as the central figure is still occupying most of the perceived space. The horizon behind both astronauts merge into a seemless line (supplemented by the reflection), while their non-identifiable faces appear to be looking at each other. They are aliens on a celestial body that has not encountered human life before. They launched a history (both social and photographic), that was already conceived with a specific agenda: colonizing the Moon. Our planet's only Moon. However, as oppose to previous explorers, like Christopher Columbus, the Apollo 11 crew already had an idea of what they would find on this uninhabited land. As noted by Tanya Sheehan, photographic meaning has been produced via the masculine emphasis on "taking", in contrast to the feminine associations of "making", although the opposite analogy can be argued for as well, taking understood as a passive verb, while making as an active one. This gendered politics in the discourse of photographic history has been the foundation to the exclusion of the latter sex, while also informing the standard aesthetic taste for lens-based media (Sheehan, 2014, p.131). In this particular context photography takes the status of an epistemic medium that is both a means of technology and journalism. However, reinterpreting a fifty-year-old scientific documentation is a delicate quest, due to our current perspective accounted to the shifting socio- political climate. Nevertheless, stating that such a historically loaded photograph would be a general representation of humankind – treatment of representation as a vernacular phenomenon – fails to address its infringement of diversity and only succeeds in underpinning the same Western, white, middle-class patriarchal system that it is employed by. Ironically enough, the next NASA Moon program including humans again has been named Artemis, another figure of Greek mythology who was not only the twin sister of Apollo, but also the goddess of the Moon and chastity. This time, NASA officials have stated their intention to send the first woman to the Moon, while also considering to execute the mission with an all-female crew. Nonetheless, it is important to note that this step does not lessen the troublesome objective of colonialization through a self-proclaimed right. Even though this notion might advance from leaving the sole role of spectatorship to women, it still does not let go of the violent practice of demarcating space, whether social, public, natural or even outer. 1 ☽: intentionally written with a capital 'M' throughout the whole essay to honour it with some agency Illustration Image 1: NASA, 1969, A triumph of human consciousness in an otherwise mindless universe, Image, viewed on 1 December 2019, . Bibliography Gohd, C. (2019, July 16). Apollo 11 at 50: A Complete Guide to the Historic Moon Landing. Space. Retrieved from https://www.space.com/apollo-11-complete-guide.html GreekMythology.com. (n.d.). Apollo. Retrieved from https://www.greekmythology.com/Olympians/Apollo/apollo.html GreekMythology.com. (n.d.). Artemis. Retrieved from https://www.greekmythology.com/Olympians/Artemis/artemis.html Jones, J. (2019, July 17). The greatest photos ever? Why the moon landing shots are artistic masterpieces. The Guardian. Retrieved from https://www.theguardian.com/artanddesign/2019/jul/17/greatest-photos-ever-moon-landing- shots-artistic-masterpieces Minh-ha, T. T. (1991). When the moon waxes red : representation, gender, and cultural politics. New York: Routledge. Mitchell, W. J. (1995). Picture Theory: Essays on Verbal and Visual Representation. Chicago: University of Chicago Press. Monzon, I. (2019, August 26). Will NASA’s Artemis Moon Mission Have An All-Female Crew?. International Business Times. Retrieved from https://www.ibtimes.com/will-nasas- artemis-moon-mission-have-all-female-crew-2818026 National Aeronautics and Space Administration. (n.d.). Artemis. Retrieved from https://www.nasa.gov/specials/artemis/ National Aeronautics and Space Administration. (n.d.). About the Moon/In Depth. Retrieved from https://moon.nasa.gov/about/in-depth/ Rose, G. and, P. Tolia-Kelly, D. eds. (2012). Visuality/Materiality: Images, Objects and Practices. Farnham: Ashgate Publishing Ltd. Sheehan, T. (2014). Photography, History, Difference. (T. Sheehan, Ed.) Hanover: Darmtouth College Press. Zylinska, J. (2017). Nonhuman Photography. Cambridge: The MIT Press. work_3pyf4xtbajfj5pthqht335j2bm ---- ¿Hacia la academización de las facultades de derecho en Chile? Un análisis teórico y comparado del conflicto de las profesiones 2014] FERNANDO MUÑOZ LEÓN: ¿HACIA LA ACADEMIZACIÓN DE LAS FACULTADES… 9Revista de Derecho Vol. XXVII - Nº 1 - JULIO 2014 Páginas 9-25 ¿Hacia la academización de las facultades de derecho en Chile? Un análisis teórico y comparado del conflicto de las profesiones Fernando Muñoz León*1 Resumen Las facultades de derecho chilenas están viviendo un proceso de cambio consistente en la prolife- ración al interior de ellas de académicos de dedicación completa y exclusiva. Ello involucra una cierta pérdida de protagonismo dentro de las mismas de los docentes que dividen su tiempo entre los tribunales y las aulas universitarias. ¿Estamos ante la profesionalización de la docencia jurídica? Este ensayo sugiere entender este fenómeno más bien como un caso de conflicto entre dos profesiones, los “académicos” y los “docentes litigantes”, al interior de las facultades. Para comprender el posible destino de este “conflicto de las profesiones”, este ensayo propone poner atención a las prácticas académicas de Estados Unidos, cuyas facultades de derecho atravesaron este proceso de academización hacia fines del siglo XIX y principios del siglo XX. Academia jurídica – profesiones – sociología jurídica Towards the academization of law faculties in Chile? A theoretical and comparative analysis of the conflict of the professions Abstract Chilean law faculties are undergoing a process of change that consists in the proliferation within them of full-time academics. This involves a certain loss of importance within them of instructors that split their time between courts and classrooms. Are we witnessing the professionalization of legal instruction? This essay suggests understanding this phenomenon rather as a case of conflict between two professions, the ‘academics’ and the ‘litigant teachers’, within the faculties. To understand the possible outcome of this ‘conflict of the professions’, this essay proposes to pay attention to the academic practices of the United States, whose law faculties went through this process of academization at the end of the 19th and the beginning of the 20th centuries. Legal academia – professions – legal sociology *1Profesor Auxiliar, Facultad de Ciencias Jurídicas y Sociales, Universidad Austral de Chile. Doctor en Derecho, Yale Law School. Correo electrónico: fernando.munoz@uach.cl. Artículo recibido el 30 de agosto de 2013 y aceptado para su publicación el 28 de mayo de 2014. 10 REVISTA DE DERECHO (VALDIVIA) [VOLUMEN XXVII - Nº 1 Introducción Creo posible sostener que la academia jurídica en Chile está experimentando un rápido proceso de cambio. Este podría ser descrito, preliminarmente, como un proceso de profesionalización, entendiendo por tal un proceso de especializa- ción del trabajo; en este caso, del trabajo académico. Así, y en un grupo importante (pero en ningún caso universal) de facultades de derecho, de ser labores realizadas en los intersticios de la actividad profesional del abogado litigante1, las siguientes están comenzando a ser labores realizadas a tiempo completo por académicos: la producción de conocimiento jurídico en la forma de publicaciones especializadas; la transmisión de dicho conocimiento a los futuros profesionales en la forma de docencia universitaria, y al resto de la comunidad mediante la extensión; y la gestión misma de las institucio- nes de educación superior, incluyendo la planificación curricular y metodológica de la docencia antes dicha. Las facultades de derecho se estarían sumando a aquella visión convencional según la cual “sin un profesorado sólido, bien preparado y comprometido, ninguna institución académica o sistema de educación superior puede ser exitoso”2. A manera de hipótesis respecto de las causas de dichos cambios, me permitiría sugerir que en ellos confluyen diversos fenómenos relacionados con la consolidación institucional del sistema universitario chileno. Entre estos fenómenos se encontrarían la masificación de las escuelas de derecho, que a su vez lleva a una competencia de mer- cado entre las mismas; la visibilización de dicha competencia mediante el surgimiento de variados rankings; la especialización de las tareas investigativas por exigencias de formación doctoral; la exclusividad contractual como estrategia monopólica de las facultades en la competencia por los mejores docentes e investigadores; el recurso a la acreditación como mecanismo de certificación de la calidad de la enseñanza; las deman- das características de los procesos de acreditación; y –last but not least– el trasplante de objetivos, prácticas y expectativas de carácter académico provenientes en forma directa de otras latitudes e indirectamente de otras disciplinas. Mientras que algunas de estas dinámicas –en particular, las primeras– no apuntan con necesidad a la proliferación en las facultades de derecho de académicos de dedicación completa y exclusiva, las últimas sí parecieran hacerlo en el presente, imprimiéndole una orientación más clara al conjunto de dichos procesos. 1 Emplearé aquí esta expresión para denominar al heterogéneo conjunto de quienes, según la expresión tan habitual, “ejercen libremente la profesión de abogado”. Por supuesto, no creo que exista una profesión de abogado. Enseñar derecho también es ejercer la profesión. Lo es, también, desempeñarse como juez, notario, defensor público, fiscal, o abogado corporativo. Ahora bien, para efectos de esta discusión, subsumiré a esta abigarrada variedad de formas de ejercer la profesión dentro de la figura del abogado litigante. Escojo a dicha figura porque a mi juicio es la manifestación alternativa al académico más frecuente en las facultades. Asimismo, escojo a una sola figura, que estimo suficientemente representativa del resto, para simplificar lingüísticamente mi discusión del conflicto entre académicos y no académicos. 2  Altbach, P. et  al. (eds), Paying the Professoriate: A Global Comparison of Compensation and Contracts, New York, Routledge, 2012, p. 3. 2014] FERNANDO MUÑOZ LEÓN: ¿HACIA LA ACADEMIZACIÓN DE LAS FACULTADES… 11 Ahora bien, formulada por un académico, ¿no sería la observación con que comienza este artículo un ejemplo de historia whig, un caso de autocomplaciente descripción de la realidad como un constante progreso hacia el presente? A fin de evitar caer en el whig- gismo, voy a sugerir una forma alternativa de entender el proceso de cambio en cuestión. Esta perspectiva involucra reconocer que no corresponde calificar al litigante que hace docencia como un no profesional. A la luz de esta premisa, es más adecuado señalar que el proceso recién reseñado consiste, en estricto rigor, no tanto en una profesionalización a secas, sino más bien en un conflicto. No un conflicto de las facultades3, lógicamente, sino un conflicto dentro de ellas entre dos grupos de profesionales del derecho: ¿los “docentes litigantes”, por un lado, y los “académicos”, por el otro? Ellos no necesariamente entran en conflicto en un sentido subjetivo, es decir, en el sentido de que sus voluntades y sus ánimos entren en mutuo combate4, sino que entran en conflicto en un sentido objetivo: los unos desplazan a los otros de posiciones de influencia y poder anteriormente soste- nidos sin mayores cuestionamientos. Para comprender esta afirmación, acometeré un análisis teórico del concepto de profesionalización. Además de observar este fenómeno, en este trabajo quiero invitar a la reflexión sobre algunas preguntas prospectivas. ¿Qué implicancias tiene para nuestro sistema universitario el paulatino desplazamiento de los “litigantes” a manos de los “acadé- micos”? ¿En qué podría consistir el nuevo modelo de Facultad de Ciencias Jurídicas nacional?¿Qué estructuras internas y externas adoptará para llevar a cabo las funciones de producción académica, entrenamiento profesional, y vinculación con el entorno social que normalmente se esperan de las instituciones de educación superior? ¿Qué oportunidades y peligros nos aguardan con este proceso? Intentaré sugerir respuestas a dichas preguntas a partir de un análisis comparado de la academia jurídica norteameri- cana. He escogido dicho caso debido a que, como he observado en un anterior artículo, la academia norteamericana ya atravesó un proceso de academización hacia fines del siglo XIX y principios del siglo XX; proceso que estuvo guiado por los argumentos y discursos justificatorios ofrecidos por Christopher Columbus Langdell y Oliver Wendell Holmes5. Aquí dedicaré mi atención, en consecuencia, no al proceso de academización sino al resultado del mismo. Por cierto, al fijar mi atención en la estructura y prácticas de las facultades de derecho se hace innecesario que analice las diferencias y similitudes entre nuestro sistema jurídico y el norteamericano6. 3 La referencia, por supuesto, es a Kant, I., El conflicto de las facultades, Madrid, Alianza Editorial, 2003. 4  Aunque tampoco es imposible que ello ocurra. En todo caso, el estudio casuístico de conflictos subjetivos entre “docentes litigantes” y “académicos” no forma parte de los objetivos de este trabajo. 5  Muñoz, F., “Langdell’s and Holmes’s influence on the institutional and discursive conditions of American legal scholarship”, Revista Chilena de Derecho, Vol. 38, 2011, pp. 217-237. 6 Estas diferencias y similitudes son habitualmente administradas mediante la dicotomía entre derecho continental y common law. El análisis clásico de dicha dicotomía se encuentra en Zweigert, K., y Kötz, H., Introduction to Comparative Law, Oxford, Oxford University Press, 1998. Se puede encontrar una evaluación contemporánea de la misma en Pargendler, M., “The Rise and Decline of Legal Families”, American Journal of Comparative Law, Vol. 60, 2012, pp. 1043-1074. 12 REVISTA DE DERECHO (VALDIVIA) [VOLUMEN XXVII - Nº 1 El sistema de las profesiones y la competencia por jurisdicción El estudio de las profesiones ha sido desde temprano una de las preocupaciones de la sociología. Los propios orígenes de esta disciplina están vinculados a los esfuerzos por comprender las consecuencias de la división del trabajo sobre la estructura social. Es lógico que esta preocupación haya llevado a los sociólogos a estudiar una de las mani- festaciones de dicha división, la configuración de diversas disciplinas o profesiones. Max Weber, Emile Durkheim y Georg Simmel contribuyeron así a construir los cimientos de la literatura sobre las profesiones7. La literatura contemporánea sobre profesiones, por supuesto, ha recorrido un largo camino desde entonces. Podemos encontrar una síntesis crítica del estudio de las profesiones en la propuesta de Andrew Abbott. Según este autor, en Estados Unidos la literatura sobre las profesiones y los procesos de profesionalización ha transitado por las siguientes perspectivas: funcionalista, estructuralista, monopolista, y culturalista. Para la perspectiva funcionalista, una profesión es un mecanismo para controlar la relación asimétrica entre expertos y clientes, y la profesionalización es simplemente la evolución de las garantías estructurales de ese control. Para la perspectiva estructura- lista, la profesión es una forma de control ocupacional; la comprensión del proceso de profesionalización involucra la explicación de los pasos que atraviesa una actividad en el desarrollo de mecanismos de control8. Para la perspectiva monopolista, el desarrollo de dichos mecanismos no es natural o espontáneo, sino que el fruto de un deliberado propósito de dominio o autoridad; las profesiones son grupos corporativos que buscan controlar rentas y estatus mediante un dominio ocupacional. Finalmente, observa Abbott, autores que trabajan en la perspectiva culturalista han retornado al foco en el rol de la experticia como un determinante de las relaciones sociales, enfatizando la autoridad cultural de las profesiones9. Abbott critica a las perspectivas antes identificadas, particularmente a la estruc- turalista, por su excesivo foco en profesiones construidas desde la autonomía social, dejando de lado a profesiones construidas al alero de la institucionalidad estatal, típicas de Europa continental. En términos más generales, critica a todas ellas por analizar y teorizar a las profesiones de manera individual, atomizada. En contraste con ello, Abbott propone entender lo profesional como un campo en que existen diversas relaciones entre profesiones; más específicamente, como un ecosistema en el cual cada profesión 7 Weber, M., El político y el científico, Madrid, Alianza Editorial, 2005; Weber, M., Economía y sociedad. Esbozo de sociología comprensiva, México, Fondo de Cultura Económica, 1964; Durkheim, É., La división social del trabajo, Madrid, Akal, 1987; Simmel, G., Sobre la individualidad y las formas sociales, Buenos Aires, Universidad Nacional de Quilmes, 2002. 8 Esta tesis incluye la detección de varios hitos por los cuales en Estados Unidos se ha construido la identidad colectiva de las profesiones: apertura de escuelas de entrenamiento profesional, desplazamiento de las mismas hacia las universidades, asociaciones profesionales locales y nacionales, aprobación de leyes que requieren la obtención de un título para el ejercicio profesional, la aparición de códigos de ética profesional. 9 Abbott, A., The System of Professions. An Essay on the Division of Expert Labor, Chicago, The University of Chicago Press, 1988, p. 15. 2014] FERNANDO MUÑOZ LEÓN: ¿HACIA LA ACADEMIZACIÓN DE LAS FACULTADES… 13 compite con otras por un determinado coto laboral. Por esto, su foco es en el sistema de las profesiones, esto es en las relaciones de competencia, colaboración y jerarquía que se dan entre ellas; y el sitio donde explorar dichas relaciones es en el control por parte de una profesión de determinadas actividades, labores, o problemáticas, vínculo de control al que denomina jurisdicción. “Analizar el desarrollo de las profesiones es analizar cómo este vínculo es creado en el contexto laboral, cómo es anclado por la estructura social formal e informal, y cómo la interacción entre los vínculos jurisdiccionales de distintas profesiones determina la historia de las profesiones individuales en sí”10. En resumidas cuentas, la competencia por jurisdicción explica el sistema de las profesiones existente en un determinado contexto. La propuesta teórica de Abbott nos sirve para conceptualizar de manera más certera el proceso de cambio identificado al principio de este trabajo. Lo que ocurre hoy en las facultades de derecho chilenas es un proceso de competencia entre dos profesiones, los litigantes docentes y los académicos, por reclamar eficazmente jurisdicción sobre las labores de docencia, investigación, y gestión universitaria. En efecto, la integración predominante del cuerpo docente por académicos de dedicación exclusiva conlleva una creciente exclusión de la conducción de la institución universitaria y de la enseñanza de los principales cursos de quienes litigan en tribunales o desempeñan otras funciones en el sistema judicial. Quisiera examinar dos registros discursivos en los cuales esta competencia por ju- risdicción al interior de las facultades de derecho ha sido visibilizada. En primer lugar, examinaré una discusión en un diario nacional entre decanos de facultades de derecho. A continuación, revisaré algunas actas de procesos de acreditación de facultades de derecho. Me parece que estos registros evidencian los imaginarios que, en representación de las dos profesiones en cuestión, se disputan el dominio jurisdiccional de las facultades de derecho. El primer registro ofrece un enfrentamiento entre dos narrativas altamente idealiza- das, casi míticas, que sustentan sus respectivas tesis sobre la orientación que debe tener la facultad de derecho en posturas sobre el personal que debe primar en ellas. Una de ellas, la que cabría calificar como tradicional, plantea que para que la facultad de derecho pueda estar exitosamente orientada al ejercicio profesional, ya sea litigioso o corpora- tivo, ella debe estar construida en torno a la figura del litigante prestigioso devenido en educador en su tiempo libre. Esta narrativa ha sido formulada por Pablo Rodríguez, Decano de la Facultad de Derecho de la Universidad del Desarrollo, en diversas columnas editoriales en el diario El Mercurio. Allí ha afirmando que, en la facultad de derecho, 10 Ídem, p. 20. Véase también ídem, p. 33: “Cada profesión está amarrada a un conjunto de labores por vínculos jurisdiccionales, cuyas fortalezas y debilidades están establecidas en el proceso mismo del trabajo profesional. Ya que ninguno de estos vínculos es absoluto o permanente, las profesiones en su conjunto componen un sistema interactivo, un ecosistema. Las profesiones compiten entre sí dentro de este ecosistema, y el éxito de una profesión refleja tanto la situación de sus competidores y la estructura del sistema mismo como los esfuerzos de la propia profesión. Cada cierto tiempo, tareas son creadas, abolidas o reformadas por fuerzas externas, con sus consiguientes desplazamientos y reajustes dentro del sistema de las profesiones”. 14 REVISTA DE DERECHO (VALDIVIA) [VOLUMEN XXVII - Nº 1 “el investigador, el docente, el filósofo del derecho y el jurista son una excepción que enaltece la profesión”, pero que “lo que Chile necesita” son “abogados para organizar y reglamentar con eficiencia la vida social”11. Asimismo, ha sostenido que los “académicos profesionales”, “sin duda útiles en ciertas cátedras, nada o muy poco aportan a la hora de ejercer el derecho vivo, cuando la norma se confronta con la realidad”12. La segunda narrativa, que podríamos calificar como revisionista, sostiene que solo mediante la incorporación de la figura transnacional del académico de tiempo comple- to, validada por las universidades más prestigiosas del mundo, la facultad de derecho contemporánea podrá alcanzar sus propósitos de una manera autorreflexiva o crítica. En el caso específico que me ocupa, esta narrativa fue planteada como una respuesta a Rodríguez por parte de Rodrigo Correa, Decano de la Facultad de Derecho de la Universidad Adolfo Ibáñez. Correa argumentó que “un sistema jurídico sano requiere de personas dedicadas a examinarlo críticamente”, las cuales “deben contar con tiempo para el constante estudio, tanto del derecho nacional e internacional como de disciplinas importantes para el derecho”, y deben tener “la libertad para criticar las decisiones que toman diversos actores del sistema jurídico”13. Como coronación de su argumento, Correa invocó explícitamente algunos modelos ultramarinos de docencia jurídica (Harvard, Oxford, Leiden, Alexander von Humboldt, París II, Pompeu Fabra), afirmando que “no debe extrañar que todas las facultades de derecho que gozan de prestigio más allá de sus fronteras” estén “integradas principalmente por académicos”14. El segundo registro al que he hecho referencia está conformado por acuerdos de acreditación tomados por agencias acreditadoras privadas y, al menos en un par de casos, por la propia Comisión Nacional de Acreditación. Estos acuerdos, como es lógico, solo reflejan el caso de las facultades que han resuelto someterse al procedimiento de acredi- tación15, el que en nuestra actual legislación es voluntario16. Ellos evidencian la dispar evaluación que, en la actualidad, reciben las facultades, por parte de la institucionalidad regulatoria universitaria, de acuerdo con el número de su personal académico. Esto se comprueba, por ejemplo, observando la retórica que acompaña la evaluación de las ca- rreras de pregrado que han obtenido el mayor número de años de acreditación. 11 Rodríguez, P., “Misión profesional de la universidad”, El Mercurio, 23 de mayo de 2009, A 2. 12 Rodríguez, P., “Sistema jurídico chileno”, El Mercurio, 19 de enero de 2011, A 2. 13 Correa, R., “Sistema jurídico chileno”, El Mercurio, 20 de Enero de 2011, A 2. 14 Ídem. 15  De acuerdo con lo informado por la Comisión Nacional de Acreditación se han sometido a este proceso trece universidades, de entre las cuales en este momento dos gozan de una acreditación de dos años (Universidad de Antofagasta y Universidad Bernardo O’Higgins), una de tres años (Universidad de Antofagasta), una de cuatro años (Universidad Católica de la Santísima Concepción), dos de cinco años (Universidad Católica del Norte y Universidad Alberto Hurtado), cinco de seis años (Pontificia Universidad Católica de Valparaíso, Universidad Austral de Chile, Universidad de Concepción, Universidad de Los Andes, Universidad de Valparaíso), y una de siete (Universidad Diego Portales). 16 Para una crítica de la voluntariedad en los procesos de acreditación, véase Muñoz, F., “La necesidad de regular la docencia universitaria en Chile: una propuesta de lege ferenda”, Revista Chilena de Derecho, Vol. 39, 2012, pp. 891-907. 2014] FERNANDO MUÑOZ LEÓN: ¿HACIA LA ACADEMIZACIÓN DE LAS FACULTADES… 15 Así, en un caso se señala que “la carrera cuenta con un cuerpo académico suficiente en cantidad y altamente calificado para sustentar el programa” y los “docentes cuentan con un elevado nivel y diversidad de formación disciplinaria, y con reconocida produc- tividad en investigación”17. En otro, se afirma que el “cuerpo académico de la carrera es suficiente en cantidad, calidad y dedicación para implementar el plan de estudios” y que la “carga de trabajo está adecuadamente equilibrada entre las funciones de docencia, investigación y gestión que deben desempeñar”18. En un tercer ejemplo se observa que el “cuerpo académico es calificado y con un número creciente de postgraduados”, así como que existe “un nivel de preparación muy bueno en un grupo importante de profesores con entusiasmo y vocación por lo que hacen”19. En otro caso se valora que la “dotación, dedicación y calificación del cuerpo docente es adecuada para llevar a cabo el plan de estudios que se ha propuesto la unidad”, al tiempo que se lamenta “la disminución de profesores de jornada completa entre 2009 y 2010”20. Respecto de otra institución se destaca que “el personal docente es calificado y competente, advirtiéndose el esfuerzo que se ha hecho para aumentar la dotación de profesores con postgrados en jornada completa”21. En un último ejemplo, el organismo acreditador valoró que la unidad aca- démica en cuestión “cuenta con un número apropiado y calificado de profesores que le permite dar cumplimiento a las funciones de docencia”, destacando que ella tiene “una dotación de 19 jornadas completas, 13 medias jornadas y 2 con un cuarto de jornada, todos con estudios de postgrado”, al tiempo que de “las jornadas completas y medias jornadas, la mayoría se encuentra adscrito a la carrera académica regular y realizan do- cencia e investigación”22. ¿Hay valoración por parte de los reguladores universitarios de la presencia de liti- gantes docentes en las facultades con alta acreditación? Al menos hay un caso en el que los acuerdos de acreditación destacan el que, junto a los profesores académicos, “existe un alto número de profesores vinculados con el ejercicio activo de la profesión, lo que es valorado por los estudiantes”23. Viceversa, en el caso de una de las carreras que obtuvieron menor tiempo de acre- ditación se critica que “la cantidad de profesores y su dedicación no es suficiente para cumplir con la misión y objetivos en las distintas áreas del quehacer de la unidad”, observación que se respalda señalando que la unidad académica “tiene dos académicos de jornada completa (Decano y Jefa de Carrera) y diez profesores de media jornada”24, 17 Qualitas, Acuerdo de Acreditación Nº 155: Pontificia Universidad Católica de Valparaíso, p. 7. 18 Qualitas, Acuerdo de Acreditación Nº 122: Universidad Austral de Chile, p. 5 19 Comisión Nacional de Acreditación, Acuerdo de Acreditación Nº 311: Universidad de Concepción, p. 4. 20 Qualitas, Acuerdo de Acreditación Nº 125: Universidad de los Andes, p. 4. 21 Agencia Acreditadora de Chile, Acuerdo de Acreditación Nº 101: Universidad de Valparaíso, p. 7 22 Agencia Acreditadora de Chile, Acuerdo de Acreditación Nº 61: Universidad Diego Portales, p. 6. 23 Qualitas, Acuerdo de Acreditación Nº 155: Pontificia Universidad Católica de Valparaíso, p. 7. 24 Qualitas, Acuerdo de Acreditación Nº 161: Universidad Bernardo O’Higgins, 7. 16 REVISTA DE DERECHO (VALDIVIA) [VOLUMEN XXVII - Nº 1 mientras que en el caso de otra carrera se criticó que “existen pocos académicos con- tratados en calidad de planta” y que “una baja cantidad tiene formación doctoral”25. El debate entre decanos y las actas de acreditación sugieren que el triunfo en la competencia por jurisdicción entre las profesiones jurídicas al interior de las facultades de derecho estará del lado de aquella profesión que logre persuadir eficazmente a los diversos actores del sistema universitario –demandantes de educación, demandantes de literatura especializada, autoridades ministeriales, agencias reguladoras y fiscalizado- ras, prensa especializada– de sus ventajas comparativas en la realización de las labores que componen el respectivo campo operativo; particularmente la formación de futuros profesionales jurídicos. ¿Quién está mejor capacitado para enseñar a nuestros futuros abogados, los litigantes docentes o los académicos? Esa es la pregunta que guía y seguirá guiando la competencia por jurisdicción al interior de las facultades. La academización de las facultades en Estados Unidos y sus críticos Hasta ahora hemos contemplado cómo nuestras facultades de derecho están inmersas en un proceso de competencia por jurisdicción entre litigantes docentes y académicos. Ahora veremos, al menos someramente, las consecuencias del triunfo de los segundos en el caso de las facultades norteamericanas26. En Estados Unidos, el proceso de academización de las facultades de derecho está íntimamente relacionado con el éxito, hacia fines del siglo XIX y principios del siglo XX, de las reformas impulsadas por Christopher Columbus Langdell como Decano de Harvard. Langdell entendía la academia universitaria como una profesión en sí misma; si miramos las cosas desde esa perspectiva, un litigante, que es un profesional de la representación de intereses jurídicos ante los tribunales, es en cambio un amateur de la investigación 25 Comisión Nacional de Acreditación, Acuerdo de Acreditación Nº 107: Universidad de Atacama, p. 4. Esta resolución rechazó la acreditación de la unidad académica, decisión que fue objeto de una reposición presentada por la institución ante el mismo organismo y donde fue desechada mediante su Acuerdo de Acreditación Nº  120. Finalmente, la decisión fue revertida mediante apelación presentada ante el Consejo Nacional de Educación, el que acreditó a la institución por dos años. 26 Estas líneas, por supuesto, podrían también haber analizado la situación europea. Un elemento, sin embargo, hacen más propicia la realidad norteamericana para su empleo como material para la reflexión local: el hecho de que en Estados Unidos, tal como acá, y a diferencia de la mayoría de los sistemas universitarios europeos, las universidades privadas juegan un rol importante tanto en la producción académica como en la formación profesional. Un importante elemento surge de ahí: la existencia de competencia de mercado entre instituciones. El modelo norteamericano, como es obvio, contiene importantísimas influencias europeas, particularmente alemanas; y ya ha encontrado recepción en países de otros continentes, como Israel; por lo que calificarle de “norteamericano” es sencillamente una simplificación propia de la construcción de tipos ideales. Por último, es importante tener presente que los sistemas universitarios norteamericano y europeo tienen definidas ya sea a nivel de legislación (Alemania) o bien a nivel de prácticas unánimemente reconocidas (Estados Unidos) diversos aspectos relacionados con la carrera académica y su estructura interna. Lo que en Chile está tímidamente empezando a delinearse, allá es the law of the land. Véase Muñoz, supra nota 16. 2014] FERNANDO MUÑOZ LEÓN: ¿HACIA LA ACADEMIZACIÓN DE LAS FACULTADES… 17 científica y la enseñanza del derecho. En palabras de James Ames, discípulo de Langdell y su sucesor como Decano de la Facultad de Derecho de Harvard, “no ha de haber duda sobre que el plantel académico deba estar compuesto casi en su totalidad de hombres que dediquen la totalidad de su tiempo a la universidad”27. Langdell y Ames fueron los pioneros de la academización actual en las facultades de derecho norteamericanas. Ello se refleja en que, hoy, en Estados Unidos es de senti- do común sostener que “los requerimientos profesionales de sus carreras generalmente impide a los docentes a tiempo parcial dedicar una atención substancial a reunirse con los alumnos fuera del salón de clases, así como de participar en el desarrollo del cu- rrículum y otros asuntos típicamente conducidos por el cuerpo docente, y de llevar a cabo con seriedad agendas investigativas que contribuyan al desarrollo del derecho”28. Es también de sentido común observar que alguien con un nombramiento académico de tiempo completo “puede contribuir al cuerpo del conocimiento con algo que el abo- gado practicante generalmente no puede: investigación que es rigurosa y sólidamente sustentada”29. Es también pacífica, no controversial, la creencia de que los académicos se caracterizan por una mayor independencia de criterio en el análisis del derecho, pues el académico “puede examinar los problemas que involucran al derecho y a las instituciones jurídicas desde un punto de vista ampliamente independiente, careciendo de clientes reales o potenciales que puedan estar mirándolo por sobre el hombro”30. Demos por establecido, en consecuencia, que el proceso de academización que nuestras facultades están viviendo dio sus frutos hace ya bastante tiempo en las facul- tades de derecho norteamericanas. Esto implica que dichas facultades pueden ser vistas como posibles ejemplos de aquello en lo que nuestras propias facultades se convertirán. Esta posibilidad se ve considerablemente aumentada si tomamos en cuenta la influencia de los académicos que se hayan visto expuestos a la cultura académica norteamericana durante sus estudios de postgrado31. En otros países, como Israel, dicha influencia ha sido considerada decisiva en la transformación de la investigación y la enseñanza 27 Ames, J., “The Vocation of the Law Professor”, The American Law Register, Vol. 48, 1900, pp. 129- 146, p. 137. Véase también Kimball, B., “The Principle, Politics, and Finances of Introducing Academic Merit as the Standard of Hiring for ‘the teaching of law as a career,’ 1870-1900”, Law & Social Inquiry, Vol. 31, 2006, pp. 617-648; y Muñoz, supra nota 5. 28 Kane, M., “The Requirement of Full-Time Faculty in American Legal Education: Responsibilities and Expectations”, Journal of Legal Education, Vol. 51, 2001, pp. 373. 29 Van Zandt, D., “Discipline-Based Faculty”, Journal of Legal Education, Vol. 53, 2003, p. 333. 30 Ibídem. 31 No sería la primera vez que hubiese una influencia explícita de la academia norteamericana en nuestro país. A partir de 1966, la Universidad de Stanford colaboró con un proyecto de reforma de la investigación jurídica nacional que involucró a las universidades de Chile, de Concepción, Católica de Valparaíso, y, en su última etapa, Católica de Chile. Este proyecto de colaboración consistió en un programa de capacitación en métodos de investigación y enseñanza de un total de veinte académicos chilenos a lo largo de un período de tres años, y resultó en la fundación del Instituto de Docencia e Investigaciones Jurídicas en Santiago en 1969. El Instituto desapareció en 1974, cuando se extinguió el financiamiento inicial para este obtenido de la Fundación Ford. Véase Merryman, J., “Law and Development Memoirs I: The Chile Law Program”, The American Journal of Comparative Law, Vol. 48, 2000, pp. 481-499. 18 REVISTA DE DERECHO (VALDIVIA) [VOLUMEN XXVII - Nº 1 jurídicas32. ¿Qué prácticas institucionales reflejan la academización de la facultad de derecho norteamericana? La mejor evidencia de la academización de las facultades norteamericanas se encuentra en el hecho de que el grueso de la planta docente (la faculty) de las escuelas de derecho norteamericanas está integrada por profesores de jornada completa y dedicación absoluta, cuyas posiciones académicas están cubiertas por la garantía de seguridad en el empleo o tenure. El tenure entrega al académico un nombramiento en titularidad caracterizado por el derecho contractual a no ver cesadas sus funciones sin justa causa. En otras palabras, es una especie de derecho o titularidad sobre la posición desempeñada. Los estándares para la regulación del tenure se fundamentan en el Statement of Principles of Academic Freedom and Tenure emitido por la American Association of University Professors en 194033. Para el período 2007-2008, por ejemplo, de los 10.673 profesores reportados por las facultades de derecho pertenecientes a la Association of American Law Schools, 7.653 profesores (el 71,7%) gozaban de tenure o estaban en posición de adquirirlo34. La regulación misma de las facultades, contenida tanto en los Estándares de Acreditación de la American Bar Association como en las directivas autorregulatorias de la Association of American Law Schools, les exige a dichas instituciones “contar con un número suficiente de profesores de jornada completa que asegure la calidad de sus programas educacionales”35. Para los académicos, en consecuencia, la primera y quizás principal meta de desarrollo profesional consiste en alcanzar el tenure. En términos directos el tenure es, entonces, una situación institucional que les entrega estabilidad en el empleo. Pero indirectamente, el tenure es también una señal de prestigio y estatus: socialmente se habla del tenured professor con una cierta reverencia; dentro de la universidad participa de la toma de decisiones colectivas; cuenta con secretarias personales y ayudantes de investigación. Por otro lado, el tenure funciona también como un marcador límite de rendimiento: quien no obtiene tenure dentro del período de cuatro años debe abandonar la institución universitaria y buscar nuevos rumbos profesionales36. El tenure se entrega fundamentalmente sobre la base de la producción académica del profesor, expresada en la cantidad y calidad de sus publicaciones y el prestigio de las revistas donde ellas alcanzan difusión. Los candidatos 32 Véase Lahav, P., “American Moment(s): When, How, and Why Did Israeli Law Faculties Come to Resemble Elite U.S. Law”, Theoretical Inquiries in Law, Vol. 10, 2009, pp. 653-697. El autor concluye que, si bien a partir de 1967 “la historia de las facultades de derecho israelíes muestran una creciente dependencia del modelo norteamericano de enseñanza jurídica”, “la mayoría de los jóvenes estudiantes que fueron a los Estados Unidos y regresaron a Israel equipados con conocimiento jurídico fueron capaces de absorber dicho conocimiento con una mirada crítica… El resultado han sido instituciones que siguen patrones provenientes de la cultura jurídica norteamericana, pero que mantienen su autonomía y una identidad propia”. Id., pp. 696-697. 33 Véase Finkin, M.; Post, R., For the Common Good. Principles of American Academic Freedom, New Haven, Yale University Press, 2009. 34 Association of American Law Schools, Statistical Report on Law Faculty 2007-2008, p. 25. 35 Kane, M., “The Requirement of Full-Time Faculty in American Legal Education: Responsibilities and Expectations”, Journal of Legal Education, Vol. 51, 2001, p. 372. 36 Véase Muñoz, supra nota 16, p. 896. 2014] FERNANDO MUÑOZ LEÓN: ¿HACIA LA ACADEMIZACIÓN DE LAS FACULTADES… 19 saben que su obtención depende de numerosos factores, incluyendo “evaluaciones po- sitivas por parte de los profesores de mayor antigüedad en su área, ubicación de sus artículos en revistas bien evaluadas, numerosas referencias a su trabajo en la literatura pertinente, y la aprobación de colegas de otras áreas”37. ¿Qué tan serias son las exigencias de exclusividad de las facultades de derecho para los tenured professors? Al menos, ellas implican que un profesor no puede desempeñarse como tal simultáneamente en más de una universidad. La excepción a esto consiste en el permiso académico (leave of absence), el que faculta al académico a desempeñarse como profesor visitante en otra institución durante un semestre o un año. Esta práctica, relativamente frecuente, le posibilita a los profesores pasar temporadas breves en otras ciudades y otras comunidades académicas. Ahora bien, el tenure, en ocasiones, puede ser suspendido para que el académico se desempeñe en cargos públicos de relevancia, como jefe de alguna agencia reguladora. También ocurre el caso de profesores que buscan acomodar su labor académica con el cargo de juez. Debido a la estructura de la judica- tura norteamericana, que no se sustenta en jueces de carrera sino en juristas nombrados tras haberse desempeñado por un cierto tiempo en actividades políticas, litigiosas o académicas, se da el caso de académicos que sean nombrados en cargos judiciales. En estos casos, los académicos suelen mantener un nombramiento de tiempo parcial en la institución universitaria38. Por último, la exclusividad sí significa que los académicos no litigan profesionalmente en tribunales. Cabe la posibilidad de que un profesor liti- gue circunstancialmente un caso de interés público, que ejerza ocasionalmente como consultor, que participe como testigo experto en un juicio o que asesore a un cuerpo legislativo; pero no es común ni bien visto, por ejemplo, que un académico sea socio en una oficina de abogados39. Junto a la tenured faculty se encuentran distintos tipos de adjunct faculty, particular- mente los profesores de redacción forense y los profesores de clínicas jurídicas. El origen de estas clínicas jurídicas se remonta a la crítica de los años 30 a la desconexión entre el enfoque teórico de la enseñanza del derecho, que enfatizaba la discusión en clases de los contenidos de sentencias de tribunales de apelación. El pionero de la enseñanza clínica fue el realista jurídico Jerome Frank por medio de su llamado a la creación de “escuelas de abogados”40. Sus críticas dieron pie a un amplio movimiento de creación de clínicas jurídicas en las escuelas de derecho, particularmente en las escuelas de “elite”. Debido a que no todas las escuelas de derecho cuentan con cursos de redacción o de 37 Carbado, D., “Tenure”, Journal of Legal Education, Vol. 53, 2003, p. 160. 38 Como ejemplos destacados podría pensarse en Richard Posner, profesor de la Universidad de Chicago y juez de la United States Court of Appeals for the Seventh Circuit a partir de 1981, y Guido Calabresi, profesor de la Universidad de Yale y juez en la United States Court of Appeals for the Second Circuit a partir de 1994. 39 Pese a ello, Brian Tamanaha ha observado que en facultades de derecho donde hay poca disciplina y compromiso con la institución es posible que “unos pocos vayan a una oficina donde realicen actividades prácticas en asociación con un estudio de abogados”. Tamanaha, B., Failing Law Schools, Chicago, Chicago University Press, 2012, p. 4. 40 Frank, J., “A Plea for Lawyer-Schools”, The Yale Law Journal, Vol. 56, 1947, pp. 1303-1344. 20 REVISTA DE DERECHO (VALDIVIA) [VOLUMEN XXVII - Nº 1 práctica, la existencia al interior de ellas es altamente valorada y constituye un valor distintivo entre distintas escuelas; un elemento que ayuda en la competencia por captar estudiantes talentosos. Así y todo, el lugar académico de los profesores de dichas asignaturas en la escuela de derecho está delimitado, y consiste en la enseñanza de las asignaturas ya indicadas. En consecuencia, hay una división clara del trabajo: el profesor de planta, un académico con la responsabilidad de producir investigación, entrena a los alumnos en el razona- miento jurídico; mientras que los profesores de la planta adjunta, algunos de los cuales comparten su tiempo entre la docencia y el litigio profesional y otros se dedican solo a la enseñanza de ramos prácticos, están encargados de enseñar destrezas prácticas, ya sea mediante clínicas o mediante cursos de redacción de documentos. Tras la obtención de tenure, la próxima meta del profesor de derecho es alcanzar una endowed chair, una cátedra nominada financiada mediante el legado de algún donante, y posteriormente alcanzar el estatus de university professor, una especie de supercátedra concedido por algunas universidades y que ocasionalmente lleva el nombre de algún donante particularmente generoso. También es frecuente que un profesor dotado de tenure cambie de una escuela a otra “por razones de sueldo, mejores condiciones laborales, mejor ubicación, mejores colegas y alumnos, y mayor sintonía entre el académico y su institución”41. En tales casos, las escuelas le reconocen al profesor el tenure ya adquirido. El problema que ocurre en algunas facultades de derecho es que, al no estar vincu- lada a la productividad académica o docente, el tenure permite a los profesores asumir una cómoda posición que le permite hacer el mínimo esfuerzo. Tamanaha ha observado que “prácticamente cualquier facultad de derecho tiene al menos unos pocos profesores que escriben poco”, problema frente al cual los decanos de derecho “han mostrado poca disposición a eliminar esta ineficiencia”42, particularmente incrementando las cargas docentes de quienes publican menos. ¿Qué mecanismos existen en la actualidad de reclutamiento del personal acadé- mico? La forma tradicional de convertirse en profesor de derecho en Estados Unidos es graduarse de una escuela de derecho de prestigio, trabajar en el comité editorial de la revista de mayor prestigio de dicha escuela, publicar un breve artículo o student note, trabajar para un juez federal como asistente o law clerk de uno a tres años, y entonces obtener un trabajo como profesor asistente en una escuela de derecho43. Este camino lleva a que el lugar donde un potencial profesor de derecho estudió tiende a prevalecer por sobre sus posteriores méritos académicos, profesionales, o docentes. Así, parado- jalmente, “la diversidad racial y de género en las plantas de profesores de derecho ha 41 Syverud, K., “The Dynamic Market for Law Faculty in the United States”, Journal of Legal Education, Vol. 51, 2001, p. 424. El comentarista nos indica que “el típico profesor se cambiará de escuela al menos una vez”. 42 Tamanaha, supra nota 37, p. 45. 43 Véase Redding, R., “‘Where Did You Go to Law School?’ Gatekeeping for the Professoriate and Its Implications for Legal Education”, Journal of Legal Education, Vol. 53, 2003, p. 596. 2014] FERNANDO MUÑOZ LEÓN: ¿HACIA LA ACADEMIZACIÓN DE LAS FACULTADES… 21 aumentado drásticamente, pero no ha habido un incremento similar en la diversidad de proveniencia educacional de los nuevos docentes”44. El mercado de entrada a la carrera académica es muy competitivo, pero hay que destacar que está altamente institucionalizado. Cada año, cientos de abogados presentan formularios de registro en el Faculty Appointments Registry de la Association of American Law Schools, la mayoría de los cuales son presentados por vía electrónica45. Tras sortear exitosamente la primera etapa de la postulación, el candidato asiste al Faculty Recruitment Conference, una feria laboral anual (conocida informalmente como el meat market) donde se entrevistará brevemente con los comités reclutadores de diversas escuelas. De allí pueden surgir algunas entrevistas (job talks) en las cuales el candidato expondrá, frente a todo el plantel académico de la escuela en cuestión, uno de sus trabajos académicos, usualmente sin publicar todavía (o en estado de work in progress). A esa altura de su vida profesional el candidato debiera ya contar con una o dos publicaciones, por lo que el presentar un trabajo no publicado permite también hacer que la entrevista sea un intercambio académico verdadero, donde eventualmente las indicaciones o sugerencias de los profesores que participan sean tomadas en cuenta en la publicación definitiva. El carácter profesional de la carrera académica ha creado tendencias que modifican la estructura de reclutamiento ya mencionada. Progresivamente las escuelas de derecho empiezan a buscar candidatos que ya hayan adquirido experiencia en investigación, siguiendo los criterios de contratación de “otras disciplinas académicas, examinando en primer lugar el entrenamiento previo del candidato y sus méritos en materia de publi- caciones y calidad de su enseñanza”46. Actualmente la tendencia mayoritaria es que los aspirantes a convertirse en profesores postulen a una fellowship académica tras haberse graduado. Dichas fellowships les permiten permanecer uno o dos años más en la escuela de derecho preparando publicaciones que les permitan entrar exitosamente al job market. Otro proceso en marcha es el rol de “la forma de educación jurídica avanzada (J.S.D.)”47; esto es, la realización de estudios doctorales propiamente tales48. Otra característica importante de la academia norteamericana, como es sabido, es su interdisciplinariedad. Lo interesante es que ella ha desencadenado también cambios paulatinos en el proceso de reclutamiento, resultantes en el incremento en la cantidad de candidatos que han cursado un doctorado en otras áreas del conocimiento. Se ha dicho que debido a ella la escuela de derecho típica “empieza a parecerse más a una universidad en miniatura –sin las ciencias físicas– que a una planta docente en particular dentro de la universidad”; un lugar donde “encontramos filósofos, economistas, críticos literarios, 44 Ídem., p. 594. 45 Syverud, supra nota 39, p. 423. 46 Redding, supra nota 41, p. 614. 47 Redding, supra nota 41, p. 614. 48 Recordemos que en Estados Unidos el título entregado comúnmente por las escuelas de derecho es el de Juris Doctor (J.D.). El Juris Scientiae Doctor (J.S.D.) es, según la jerga académica norteamericana, un research degree; quien lo obtenga debe no solamente haber cursado asignaturas lectivas sino también haber acreditado su capacidad de producir conocimiento mediante la realización de una tesis. Es, en suma, un doctorado. 22 REVISTA DE DERECHO (VALDIVIA) [VOLUMEN XXVII - Nº 1 académicos de estudios culturales y de estudios femeninos”, “historiadores y sociólogos y sicólogos; antropólogos y teólogos”49. Una vez que el académico se ha incorporado a la facultad, ¿cómo se estructura su carga docente? En la actividad del profesor de planta encuentra un lugar protagónico la enseñanza de un número mínimo de cursos semestrales cada año, típicamente tres o cuatro50. Normalmente el profesor enseñará algún seminario, alguno de los masivos cursos del currículum de primer año (Constitutional Law, Contracts, Torts, Procedure), y alguno de los cursos más especializados y que no siempre son obligatorios para todos los alumnos (Federal Courts, Criminal Law, Administrative Law, Labor Law, entre otros). Hay que señalar que la estructura de departamentos temáticos existente en Chile y proveniente de la academia europea está ausente de la escuela de derecho norteamericana; no hay departamentos de derecho público, derecho privado, etcétera. Por lo demás, los profesores cruzan frecuentemente las fronteras de lo que para nosotros pertenece a una u otra área del derecho. Esto lleva a que se den casos como los de un profesor enseñando, durante un mismo semestre, filosofía de la acción humana y responsabilidad extracontractual51. Otro elemento central en la vida académica norteamericana es la publicación. Un profesor que no publique constantemente se enfrenta a la presión social de sus pares, fenómeno que es popularmente conocido como publish or perish52. La gran paradoja, desde luego, de dicha presión por publicar es que la vida de los académicos (incluyendo su obtención de tenure) depende de las decisiones editoriales de alumnos de segundo año, quienes ofician de directores de prácticamente la totalidad de las revistas de derecho norteamericanas53. Entre las críticas que esto despierta hoy se encuentra la afirmación de que los editores estudiantiles se guían en primer lugar por las credenciales académicas de los autores, dejando fuera a los autores cuyas credenciales sean a sus ojos insatisfacto- rias. Por esto, uno de los procesos de reforma actualmente en curso es la incorporación de profesores con tenure como asesores de las revistas, así como el desencadenamiento de una guerra soterrada (o a veces no tanto) entre revistas student-edited y revistas peer reviewed 54 por captar ciertos nichos editoriales. 49 Luban, D., “Legal Scholarship as a Vocation”, Journal of Legal Education, Vol. 51, 2001, p. 168. 50 Kane, supra nota 28, p. 373. 51 Estoy pensando en el ejemplo de Jules Coleman, quien el 2008 dictara en la facultad de derecho de Yale al mismo tiempo el curso de Torts y un seminario de filosofía analítica titulado Law and the Reactive Attitudes. 52  Por supuesto, como he observado anteriormente, hay algunos profesores a quienes dicha presión les afecta poco. 53 Este modelo data de fines del siglo XIX. Con todo, recuerde el lector que las escuelas de derecho en Estados Unidos constituyen una professional school, a la cual se postula tras obtener un bachelor en un college y a menudo tras haber trabajado como paralegal en un estudio jurídico o haber realizado otras labores que permitan incrementar las posibilidades de aceptación en las escuelas de derecho (que no solo exigen un alto puntaje en el Law School Admission Test, sino también la capacidad de mostrar aptitudes profesionales y de liderazgo). El alumno de segundo año de derecho norteamericano, en consecuencia, tiene una formación totalmente distinta a la del alumno de segundo año chileno, quien es básicamente poco más que un egresado de enseñanza media. 54 Hay que aclarar que ambos tipos de revistas tienen comité editorial; la diferencia es que en un caso son estudiantes y en el otro son profesores (peers). 2014] FERNANDO MUÑOZ LEÓN: ¿HACIA LA ACADEMIZACIÓN DE LAS FACULTADES… 23 Otro elemento central de la práctica académica norteamericana es la existencia de seminarios o workshops organizados regularmente por los profesores. Entre ellos el más importante es el faculty workshop, orientado colectivamente a todos los profesores sin importar su área de especialidad y en el cual se discute semanalmente un paper de elabo- ración de algún miembro de la comunidad académica. Este seminario “es un elemento ineludible del ambiente de una escuela de derecho hoy, que cumple tanto funciones sociales como intelectuales dentro de la comunidad docente”55. Conclusión: el proceso chileno en marcha Los recientes procesos de ampliación de plantas académicas con académicos gra- duados en programas doctorales y de dedicación completa parecieran señalar que el modelo tradicional de facultad de derecho está en retirada. Todo esto, cabe destacar, no sugiere que dichas facultades estén olvidando su rol de formadoras de profesionales. Lo que indica es que estaríamos frente a un paulatino triunfo de los académicos en su conflicto con los docentes litigantes sobre la jurisdicción de la enseñanza del derecho. En ese proceso, las experiencias de otras sociedades que ya han atravesado ese proceso, como la norteamericana, debieran servir como insumo a nuestra discusión local. Algunas de sus instituciones debieran ser revisadas entre nosotros; si bien se hace necesario, como he argumentado anteriormente, la creación de un estatuto que regule y proteja la función académica similar al tenure, también deben estar debidamente reguladas en dicho estatuto la formación y la productividad docente y académica que se le deben exigir al académico. Los mecanismos normativos que sean empleados para alcanzar esta regulación, y que deberán incluir a lo menos estándares legislativamente definidos y criterios reglamentariamente determinados por la autoridad educacional, deberán hacerse cargo de la diversidad del sistema universitario; sin embargo, tal diversidad no puede ser excusa para la consagración de un sistema tan desregulado como el que actualmente existe en la materia. Adicionalmente, la academización chilena debe estar consciente del peligro de que ella involucre un distanciamiento del ejercicio profesional, como algunas voces críticas sostienen que ha ocurrido en Estados Unidos56. En el presente, el mejor argumento de los académicos en su conflicto con los docentes litigantes es que ellos están en mejores condiciones que aquellos de elaborar mecanismos de enseñanza del derecho que poten- cien la práctica. Por último, existen prácticas en el academizado medio norteamericano que pueden servir de inspiración para nuestras propias facultades. 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Zweigert, K., y Kötz, H., Introduction to Comparative Law, Oxford, Oxford University Press, 1998. work_3smanu444rf6plyljjfrxpfd3e ---- “You Could Call It Magic”: What Parents and Siblings Tell Preschoolers about Unobservable Entities This article was downloaded by: [University of Toronto Libraries] On: 22 April 2013, At: 13:08 Publisher: Routledge Informa Ltd Registered in England and Wales Registered Number: 1072954 Registered office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH, UK Journal of Cognition and Development Publication details, including instructions for authors and subscription information: http://www.tandfonline.com/loi/hjcd20 “You Could Call It Magic”: What Parents and Siblings Tell Preschoolers about Unobservable Entities Caitlin F. Canfield a & Patricia A. Ganea b a Boston University b University of Toronto Accepted author version posted online: 27 Mar 2013. To cite this article: Caitlin F. Canfield & Patricia A. Ganea (2013): “You Could Call It Magic”: What Parents and Siblings Tell Preschoolers about Unobservable Entities, Journal of Cognition and Development, DOI:10.1080/15248372.2013.777841 To link to this article: http://dx.doi.org/10.1080/15248372.2013.777841 Disclaimer: This is a version of an unedited manuscript that has been accepted for publication. As a service to authors and researchers we are providing this version of the accepted manuscript (AM). Copyediting, typesetting, and review of the resulting proof will be undertaken on this manuscript before final publication of the Version of Record (VoR). During production and pre-press, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal relate to this version also. PLEASE SCROLL DOWN FOR ARTICLE Full terms and conditions of use: http://www.tandfonline.com/page/terms-and-conditions This article may be used for research, teaching, and private study purposes. Any substantial or systematic reproduction, redistribution, reselling, loan, sub-licensing, systematic supply, or distribution in any form to anyone is expressly forbidden. The publisher does not give any warranty express or implied or make any representation that the contents will be complete or accurate or up to date. The accuracy of any instructions, formulae, and drug doses should be independently verified with primary sources. The publisher shall not be liable for any loss, actions, claims, proceedings, demand, or costs or damages whatsoever or howsoever caused arising directly or indirectly in connection with or arising out of the use of this material. http://www.tandfonline.com/loi/hjcd20 http://dx.doi.org/10.1080/15248372.2013.777841 http://www.tandfonline.com/page/terms-and-conditions ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 1 “You Could Call It Magic”: What Parents and Siblings Tell Preschoolers about Unobservable Entities Caitlin F. Canfield1,, Patricia A. Ganea2 1Boston University, 2University of Toronto Correspondence concerning this article should be addressed to Caitlin F. Canfield, Department of Psychology, Boston University, Boston, MA 02215 Tel.: 617-358-5369; Fax: 617-353-6933 E-mail: ceford@bu.edu Abstract How can we explain children’s understanding of the unseen world? Young children are generally able to distinguish between real unobservable entities and fantastical ones, but they attribute different characteristics to and show less confidence in their decisions about fantastical entities generally endorsed by adults, such as Santa Claus. One explanation for these conceptual differences is that the testimony children hear from others about unobservable entities varies in meaningful ways. While this theory has some experimental support, its viability in actual conversation has yet to be investigated. Study 1 sought to examine this question in parent-child conversation, and showed that parents provide similar types of content information when talking to children about both real entities and entities that they generally endorse. However, parents use different pragmatic cues when they communicate about endorsed entities than they do when talking about real ones. Study 2 showed that older siblings used discourse strategies similar to those used by parents when talking to young children about unobservable entities. These studies indicate that the types of cues children use to form their conceptions of D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 2 unobservable entities are present in naturalistic conversations with others, supporting a role for testimony in children’s early beliefs. In many fields of knowledge, children learn through active exploration of their environments. Through perceptual observation, imitation, and even play they are able to discern the roles of the people, objects, and actions that surround them. This has advanced the idea of the child-as-scientist in much historical and current developmental theory (Piaget, 1954; Gopnik, Meltzoff, & Kuhl, 1999). However, it is sometimes impossible for children to rely on such direct experience, either because an entity, like a microscopic being, is difficult to observe, or because it is impossible to see, as is the case with abstract concepts such as infinity or fantasy entities like unicorns. In these cases, children must depend on the testimony of others (Harris & Koenig, 2006). This testimony hypothesis proposes that the verbal input children receive from others varies in important ways, and that these variations inform children’s conceptions of the unseen world (Harris & Koenig, 2006). Such variations in testimony arise in both the content of speech as well as in other, more subtle, discourse cues. For instance, children may hear the same types of information about both historical figures (“Christopher Columbus sailed in a big boat.”) and fantastical ones (“Santa Clause rides in a sleigh.”), but they are unlikely to ever hear explicit statements of reality or belief when they hear testimony about historical people (Harris, 2007). Although most previous research on children’s understanding of unobservable entities has focused exclusively on children’s conceptions (e.g., Harris, Pasquini, Duke, Asscher, & Pons, 2006; Rosengren & Hickling, D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 3 1994; Sharon & Woolley, 2004), recent research has begun to assess the efficacy of the testimony hypothesis. Woolley, Ma, and Lopez-Mobilia (2011), for instance, suggest that there are two basic tenets of the testimony hypothesis: that conversation about different types of unobservable entities actually differs, and that children are sensitive to these differences. They examined the second of these principles in an experimental paradigm in which children watched a video of two experimenters talking to each other about a novel entity. They found that preschoolers as young as 3 years of age were able to determine the reality status of the entity when explicit statements (e.g., “Bilbies are real. I believe in them.”) were present in the verbal input. By 5 years of age, children could pick up more subtle cues, such as statements that presume an entity’s existence (e.g., “We saw a baby dugong being born!”), in assessing whether an entity was real or not (Woolley et al., 2011). Earlier research has also indicated that children can use statements about belief or denial to make judgments about an entity’s reality status (Woolley & Ma, 2009). Thus, it seems that by the time they enter kindergarten, children are sensitive to discourse cues that relate to the reality status of unobservable entities. The first tenet of the testimony theory, however, remains unexplored. We do not know to what extent the naturalistic input that children receive about non-observable entities actually varies across different categories. Conversations between young children and their parents and older siblings provide an important starting point for an investigation of such input. Much of the testimony children hear about unobservable entities, especially early in life, comes from family members in unstructured conversations, but not much is D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 4 known about whether and how these conversations differ based on the type of entity discussed. Children’s Sensitivity To Cues In Naturalistic Conversation Although there has been little examination of parent-child conversations about unobservable entities, it is clear that children generally are eager to learn from important and familiar others (see Csibra & Gergely, 2009; Gelman, 2009), and it seems that they readily accept and internalize everyday assumptions about some non-observable entities from their parents. For instance, during the preschool years, children acquire the tendency to refer to the heart as the source of emotions (Gottfried & Jow, 2003). Recent studies have also indicated that infants and young children are sensitive to a variety of conversational cues in parents’ speech. Gallerani, Saylor, and Adwar (2009), report that infants as young as 11 months of age are able to use the properties of their mothers’ speech to differentiate types of reference. Mothers use more mental state terms, such as “remember,” when talking about absent objects, and 11-month-old infants are able to distinguish between these variations and respond appropriately, by looking toward the place an absent object was last seen (Gallerani et al., 2009). Mothers also seem to talk more about their actions when engaging in pretend scenarios, such as eating a pretend snack, than when engaging in real ones (Lillard & Witherington, 2004). While young infants do not seem to use this information to advance their understanding of pretend play, they do use other aspects of pretend interactions, such as mothers’ looking at them and smiling after performing an action, to distinguish between a pretend and a real action (Lillard & Witherington, 2004). Such behavioral cues may make complex concepts easier D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 5 to understand, as even high level physicists use gestures to convey dynamic aspects of complicated physical processes (Ochs, Gonzales, & Jacoby, 1996). Children can also use speaker-specific cues, such as a speaker’s confidence, to assess the value of his or her testimony. Jaswal and Malone (2007) had an adult experimenter label an ambiguous object in either a straightforward manner (“That’s a spoon”) or a more hesitant manner (“I think that’s a spoon”) and then asked 3-year-old children to demonstrate the object’s function. The children displayed more label-based functions when the speaker had been confident than they did when the speaker had used “I think.” Further, 2-year-olds are able to use speech disfluencies—pauses such as “uh” or “um”— to attend to new or infrequent words and infer a speaker’s meaning (Kidd, White, & Aslin, 2011). Thus, young children can use linguistic cues in others’ speech to infer both the meaning and quality of the testimony they hear. The goal of the current study is to determine if these types of cues—to which we know children are sensitive—occur in the testimony children hear from both parents and siblings about different types of unobservable entities. If discourse about unobservable entities does vary according to the type of entity discussed, this would provide evidence for the first tenet of the testimony hypothesis and would suggest that variations within conversations account for children’s varying conceptions of different types of unobservable entities. How Children Think About Unobservable Entities D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 6 A large body of research on children’s conceptions of unobservable entities suggests that children readily endorse the existence of several entities which they could not possibly have seen, indicating that they are not simply taking an “empiricist” view of the world (Harris, 2012). Neither do children merely believe in all entities that they hear about from others; they rarely affirm the existence of imaginary creatures like dragons (Harris, 2012). Further, although 4- and 5-year-old children consistently claim that fantasy entities with strong social support (i.e. “endorsed” entities, such as Santa Claus) exist, when asked to describe the characteristics of those entities, they separate them from real entities in much the same way adults do. They attribute significantly more human-like physical and social properties to real entities than they do to fantasy entities, even though they only correctly categorize endorsed entities as “not real” about one-third of the time (Sharon & Woolley, 2004). Similarly, Harris, Pasquini, Duke, Asscher and Pons (2006) have found that children have a clear and confident dichotomy between those entities that they believe are real (e.g., germs, Santa Claus) and those that they believe do not exist (e.g., ghosts). In addition, while young children generally categorize both scientific and endorsed entities as real, they divide them in more subtle ways. For instance, even though children provide the same types of explanations for their beliefs in scientific and endorsed entities, they are more confident in the existence of scientific entities, and are more likely to claim that other people also believe scientific entities exist (Harris et al., 2006). The Current Study D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 7 To summarize, children distinguish among unobservable entities, making subtle distinctions between scientific entities and endorsed entities, even when they classify both as real. Because these entities are unseen, researchers such as Harris and Woolley have theorized that children depend on others’ testimony in forming these conceptions, and previous research demonstrates that children are able to track and use cues in others’ speech to determine the reality status of an entity, at least in controlled experimental settings. Do children’s naturalistic conversations with others provide the same types of cues that experimental data has shown to influence their beliefs about nonobservable entities? If so, how do these cues differ when different types of entities are discussed? Do these variations in everyday testimony about nonobservable entities provide cues that enable children to form different concepts? To answer these questions we asked parents (Study 1) and older siblings (Study 2) to speak with young children about a variety of unobservable entities. First, we hypothesized that the naturalistic conversations would display the cues used in previous experimental work focused on children’s conceptions of unobservable entities. Second, we hypothesized that the testimony young children are exposed to would vary in content across entity types, and that it would especially vary in the types of subtle cues that can guide children’s beliefs—such as cues to consensus, speaker confidence, or placement in the real world (e.g., examples). If the testimony children hear from others does differ depending on the type of entity discussed, this would provide evidence for more than simply the feasibility of the D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 8 testimony hypothesis put forward by Harris and colleagues. It would indicate that children actually encounter linguistic cues about the nature, including the reality status, of different entities in their day-to-day lives. This has direct relevance to theories of children’s concept formation and supports previous work suggesting that children form, update, and elaborate their concepts of unseen entities through their sensitivity to both direct and more subtle cues in the testimony they hear. Studies investigating the actual linguistic input children receive have thus far been missing from this field of research, and thus, the current studies will specify the role of others’ input in young children’s learning. To provide a clear picture of potential variations in testimony, parents in Study 1 were asked to talk about topics in scientific, historical, endorsed and non-endorsed categories. Previous research on children’s conceptions of unobservable entities has suggested that children think about generic classes of fantastical entities differently than they think about specific, endorsed fantasy entities, and that they reason differently about real, invisible entities than they do about fantastical ones (Harris et al., 2006; Rosengren, Kalish, Hickling, & Gelman, 1994; Sharon & Woolley, 2004). Recent research has also indicated that young children sometimes have trouble determining the reality status of unfamiliar historical figures (Corriveau, Kim, Schwalen, & Harris, 2009). The specific entities chosen for the parent-child conversations were based on previous research, and were similar to those used in studies assessing children’s conceptions of unobservable entities (i.e. Harris et al., 2006). This enabled us to better relate the current findings to the previous literature. Further, for each category we chose topics for which children had D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 9 some previous knowledge, so that we could assess cues encountered in parents’ everyday conversations, rather than in conversations that are focused on explicit teaching. STUDY 1 Method Participants A total of 48 children participated, each with one parent, almost all of whom were mothers (87.5%). The children were divided into three age groups: 3-year-olds (N = 16; range = 2;11 – 3;7; mean age = 3;3), 4-year-olds (N = 16; range = 4;1 – 4;10; mean age = 4;6), and 5-year-olds (N = 16; range = 5;0 – 5;11; mean age = 5;3). There were approximately equal numbers of males (N = 23) and females (N = 25). The parent-child dyads were drawn from a community sample in Massachusetts, and were mostly well- educated, middle- to upper-middle-class European Americans. More than three-quarters of the parents in the current sample had a Bachelor’s degree or higher (89.5%; N = 85), and in only one family neither parent had a college degree. More than half of the families reported practicing a religion (60.4%), although level of religiosity was not directly assessed. Procedure Parent-child dyads were asked to converse in an informal sitting room setting. Parents were told that the researchers were interested in how children learn from conversations about things that they cannot see or experience directly. Children were given small prizes for their participation, but no incentives were provided for parents. Parents and children D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 10 were given four possible topics to talk about in each of four categories: scientific, historical, endorsed, and non-endorsed. Categories were not named for the parents. Instead, parents were simply presented with the topics, four at a time, and were asked to choose one from each group to talk about. The topics included the brain, germs and viruses, electricity, and magnetism in the scientific category; Christopher Columbus, Mother Theresa, Princess Diana, and John F. Kennedy in the historical figures category; God, Santa Claus, Easter Bunny, and Tooth Fairy in the endorsed category; and unicorns, mermaids, dragons, and witches in the non- endorsed category. Presentation order of the topics was counterbalanced across parent- child dyads. There were no time constraints placed on the conversations. Sessions were video recorded starting when the parent and child entered the sitting room, and the videotapes of the conversations were transcribed for coding. Coding The conversations were first transcribed for all participants. Then the transcripts were coded into various categories (described below) by one coder. Categories were based on content and pragmatic cues that emerged during pilot testing. Reliability of coding was conducted on 50% of the transcripts. Cohen’s kappa fell within the acceptable range for coding in the Scientific (.85), Historical (.83), Endorsed (.80), and Non-Endorsed (.77) categories, as well as for the sample overall (.81). All disagreements were resolved through conversation between the coders. D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 11 Endorsement Of Entities Whether parents affirmed or denied the existence of an entity was coded using a binary rating. This rating included explicit statements regarding the reality or invented nature of the entity, as well as more implicit indications as to whether the entity was real or imaginary. Parent Discourse Parents’ utterances were also coded for a number of discourse cues. Because previous research has indicated that young children can use both the content of conversations as well as the way things are said to determine the meaning of others’ testimony, the coding of parent’s discourse included both the content and form of the testimony provided. Conversations were coded for 17 possible cues, derived from a pilot study of 16 parent- child dyads. In the pilot study, two independent coders categorized each parent statement by its content and pragmatic properties, resulting in cues measured in the current study. The frequency with which each parent used each of the 17 cues was recorded for each topic category. While some content cues may be specific to the types of entities discussed in these conversations, the pragmatic cues closely matched those studied in previous work on how children can learn from conversation. After coding, those cues that were used by at least one-third of the parents in the sample were analyzed. Both spontaneous explanations by parents and answers to children’s questions were coded. Examples of phrases in each category are included in Table 1. The cues through which possible D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 12 changes in the content of explanations, from here on called content cues, could be measured included: Actions. Utterances that involved describing the things that the current topic did, or could do, were coded as actions. Physical Features. Physical features was used to code descriptions of what an entity looked like, including parts of that entity or physical characteristics common to the entity. Internal Features. Utterances that involved aspects of personality, or intrinsic qualities or characteristics of an entity were coded as Internal Features. Location. Utterances that included a location were coded as such. These included references to where entities lived or were from, as well as where to find entities that did not share the same characteristics of personification. Fantastical locations or locations indicating that an entity did not exist (e.g., “Unicorns are only in stories.”) were also coded as Location statements. Related Actions. When parents spoke about the actions of other people or other entities in relation to the topic entity, those utterances were coded as related actions. Traditions that the family or that people in general carry out, as well as more specific behaviors related to the topic entity were among the utterances included in this category. D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 13 Cues that related to the properties or form of the parents’ discourse, called pragmatic cues from here on, were those that related more to the way in which information was conveyed, rather than the information itself. These cues include both linguistic and para- linguistic cues, and provided a context for parents’ testimony. These included: Lack of Expertise. Utterances that conveyed a parent’s own doubts about the existence of an entity, or explanations that indicated the parent was unsure about the entity’s characteristics were coded as Lack of Expertise. Lack of Consensus. Statements concerning variation in other people’s beliefs about an entity were coded as Lack of Consensus. Real-world Examples. Utterances that included real-world examples were coded as such. These included things that had happened to the parent or child, things that might happen, and general observations about the world (e.g., “Lightning carries electricity.”). Examples often conveyed the same information about an entity as other content-related strategies, such as physical features of an entity or related actions, but did so by referencing real events or prior experience. Analogy. Utterances in which the parent compared the topic entity to something known to the child were coded as analogies. D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 14 Demonstrations. As well as linguistic cues, parents’ use of gestures and other physical demonstrations to aid in their explanations were coded. Children’s Reality Status Comments. In addition to parents’ cues, the frequency of children’s spontaneous comments about the reality status of the entities discussed, as well as the number of children who mentioned an entity’s reality status, was coded. Results Parent and child conversations lasted, on average, 10 minutes and 6 seconds, and were generally evenly split between topic categories (Table 2). While parents spoke longer with older children than with younger children, there were no significant differences between the age groups in length of conversation, or in the proportion of each overall conversation that was spent on each category. Further, there were no significant conversation time differences between the categories of entities. Preliminary analyses using repeated measures ANOVA showed a significant difference in discussion of related actions across age groups, F(1, 182) = 11.23, p < .001, Ș2 = 0.06. However, as this was the only difference involving age, gender, or order of topic presentation, all groups were collapsed for subsequent analysis. The proportion of parents who chose to talk about each entity can be found in Table 2. D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 15 Parents’ affirmation of an entity was analyzed according to the category of unobservable entity they were discussing. The number of parents who affirmed or denied the existence of the entity discussed in each category is presented in Figure 1. We conducted a logistic regression (R2 = .37) to determine whether parents’ affirmation of an entity was related to the category to which the entity belonged. Parents were significantly more likely to deny the existence of non-endorsed entities than they were to deny the existence of scientific entities (ȕ = 4.49, p < .001), historical figures (ȕ = 4.49, p < .001) or endorsed beings (ȕ = 1.97, p < .001). Parents were also more likely to deny the existence of endorsed beings than they were to deny scientific entities (ȕ = 2.52, p < .05) or historical figures (ȕ = 2.52, p < .05) Children’s spontaneous remarks about the reality status of the various entities closely matched the endorsement of parents. They differed significantly in how often they mentioned the reality status of the entities across category, F(3, 188) = 12.86, p < .001, Ș2 = 0.17. On average, more children commented on the reality status of non-endorsed entities than any other category of entity (N = 20, 41.7%). Of those, 15.0% claimed the entity was real, 70.0% said the entity was not real, and 15.0% mentioned the reality status, but remained undecided as to the entity’s nature. More children also commented about the reality status of endorsed entities (N = 11, 22.9%) than either scientific or historical topics, with 54.5% of those children claiming the entity was real and 45.5% claiming it was not. D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 16 Next we conducted a cluster analysis, using Ward’s minimum variance method and a squared Euclidean distance, of the mean frequencies of all discourse cues used by parents across all four topics discussed. The cluster analysis revealed three distinct clusters of discourse cues. One cluster encompassed the scientific and endorsed categories, a second one included the non-endorsed category alone, and a third cluster included the historical category. We conducted a series of repeated measures ANOVAs to determine whether parents differed in the discourse cues they used across clusters. Mauchly’s tests of sphericity indicated that the sphericity assumption was violated for several cues, so degrees of freedom were corrected using Greenhouse-Geisser’s estimates of sphericity where appropriate. Results from the ANOVAs are displayed in Table 3. Parents varied in several features of the content of their conversations across the three clusters. They differed in their discussions of physical features, of actions, and of the locations of the topic entities across clusters. Planned Scheffe pairwise comparisons revealed that parents relied on physical descriptions of entities significantly more frequently when talking about non-endorsed entities (M = 3.06, SD = 2.21) than they did when talking about entities in either the historical cluster (M = 0.40, SD = 1.10) or the scientific and endorsed cluster (M = 0.80, SD = 1.04), which may indicate that these conversations were more superficial in nature. Interestingly, parents were significantly less likely to talk about the actions of historical figures (M = 2.40, SD = 1.79) than they were to do so for non- endorsed entities (M = 3.91, SD = 3.03) or scientific and endorsed entities (M = 3.69, SD = 2.34). However, they were more likely to talk about the locations where historical D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 17 figures were from (M = 1.26, SD = 1.07) than they were to discuss places associated with scientific and endorsed entities (M = .91, SD = 1.31). Parents also varied in their use of related actions, talking about the actions of others related to the topic entity significantly more often when discussing scientific and endorsed entities (M = 1.43, SD = 1.93) than when talking about non-endorsed beings (M = 0.26, SD = 0.61). Because preliminary analyses revealed an age difference in parents’ use of related actions, individual ANOVAs were undertaken for each age group. The results of the overall sample remained true for parents of three-year-olds, F(2, 63) = 3.62, p < .05, Ș2 = 0.14, and five-year-olds, F(2, 59) = 4.26, p < .05, Ș2 = 0.25. It did not hold for parents of four-year-olds, although there was a trend in the same direction, F(2, 62) = 1.86, p = .16, Ș2 = 0.07. Discussing the actions of other people in relation to scientific and endorsed entities may serve the purpose of connecting these entities to the real world. Parents varied in few of the properties of their testimony across clusters. However, their use of examples and analogies did differ significantly. Similar to the trend observed for related actions, parents used significantly more examples when talking about scientific and endorsed entities (M = 1.52, SD = 1.50) than they did when talking about non- endorsed entities (M = 0.45, SD = 0.72) or historical figures (M = 0.83, SD = 0.80), again, connecting both scientific and endorsed entities to reality in a specific way. On the other hand, they used analogies most often when talking about non-endorsed entities (M = 0.62, SD = 0.95). Rather than indicating that these entities do exist, the way a real-world D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 18 example might, analogies may suggest that non-endorsed entities are “like” real things, but are different. Although the scientific and endorsed categories fell into the same cluster, we were interested in determining if there were any differences in the discourse cues used when discussing entities in these two clusters. No differences were found in the content cues that parents used across these two categories, but parents did use different pragmatic cues when speaking about scientific entities than they did when talking about endorsed entities. For instance, although they rarely explicitly denied endorsed beings, they were more likely to indicate a lack of expertise (F(3, 187) = 3.32, p < .05, Ș2 = 0.07) or consensus (F(3, 187) = 3.46, p < .05, Ș2 = 0.07) when speaking about such entities than they were when talking about scientific entities. Parents were also more likely to use gestures and other physical demonstrations to aid their explanations when describing scientific concepts, in comparison to endorsed entities. Their use of these cues diverged significantly across the two categories, F(3, 187) = 6.77, p < .001, Ș2 = 0.10. Discussion These results indicate that parents use similar content cues when talking about scientific and endorsed entities, and they do not differ much in their discussions of historical figures. However, parents’ discourse cues differ dramatically in conversations about non- endorsed entities. These clear differences in the content of parents’ testimony may explain the confident dichotomy children draw when determining what is real and what is not. D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 19 However, more subtle variations arise in the pragmatic cues parents use when talking about scientific and endorsed entities, and these may account for children’s lack of confidence in their knowledge about endorsed entities. Parents use more pragmatic cues—such as animated gestures—when talking about scientific entities, and they also show more confidence in their explanations of these real entities, whereas they tend to indicate a lack of expertise or consensus far more often when talking about endorsed beings. These cues may indicate to children that endorsed entities are different from both non-endorsed and scientific entities, allowing children more room for interpretation and possibly encouraging them to pay even more attention to such pragmatic cues as they try to determine the nature of those entities. This was supported in the examination of children’s spontaneous comments about the reality status of the different types of entities. They were most likely to talk about the reality status of non-endorsed entities, demonstrating, as has been shown in previous studies, their confidence in the fantastical nature of these beings. Further, although they also talked about whether endorsed entities were real more often than they did for scientific entities or historical figures, these comments were made with less confidence, including phrases such as “I guess” or being expressed as questions. The current research provides the first evidence for the first tenet of the testimony hypothesis, indicating that parents do talk differently about real entities than they do about fantastical ones, and that they speak differently about endorsed entities than they do about non-endorsed ones. An alternative interpretation may be that parents do not D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 20 actually speak about different types of unobservable entities differently, but that the differences in the content of parents’ speech about non-endorsed entities stems from the entities provided by the experimenters. For instance, it could be that parents can more easily describe the physical features of dragons than they can germs. While this may be the case, parents spoke about physical features more often for non-endorsed entities than they did for either endorsed entities or historical figures as well, and these topics are also arguably easier to describe physically than scientific concepts. Further, physical features dominated the parent-child conversations about non-endorsed entities, accounting for almost 30% of their total discourse, while making up less than 10% of their discourse in the other categories. This lends support for the interpretation that these conversations were simply more superficial in nature, relying largely on description, rather than expanding into more detailed discussion. Another possibility is that young children’s differential beliefs about various types of unobservable entities stems not from the differences in content and pragmatic cues they perceive in testimony from a single source, but from differences in testimony they receive from several sources. For example, although children are unlikely to encounter anyone who believes that germs are large, they may encounter people who believe that Santa Claus is imaginary. One clear source of this possible conflict can be found in the testimony that older siblings provide to young children. Older siblings speak to young children about unobservable entities in both casual conversation and through direct teaching. Study 2 was aimed to examine the way in which older siblings talk to young children about unobservable entities. D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 21 STUDY 2 If young children hear varying testimony about unseen entities from different sources, siblings may be as important a source of information as parents are. Indeed, siblings are important sources of learning for young children. Older siblings are more likely than familiar older peers to spontaneously offer instruction, and to allow younger children to have control over portions of a task in a cooperative building paradigm (Azmitia & Hesser, 1993). They are also more likely than peers to provide positive feedback and explanation for mistakes. Compared to parent-child conversation, studies of conversations between siblings seem to indicate that siblings and parents are quite similar in the information they provide to young children. In one study that examined conversation during play, for instance, both older siblings and parents used labels repeatedly when speaking to toddlers (Perez- Granados, 2002). Both groups were also most likely to use referential labels for objects over other types of labels. However, siblings were less likely to use labels in action, that is, during the course of play, than parents were. They were also less likely than parents to use labels as a collaborative strategy, preferring instead to model references to objects for their younger siblings. Thus, while older siblings do not seem to be as supportive as parents in affording learning opportunities for young children in conversation, the information they provide does not differ from that provided by parents. D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 22 Therefore, we hypothesized that, rather than being a point of potential conflict, older siblings’ testimony would closely resemble parents’ testimony, and many of the same discourse cues would be used. In study 2, we examined cues used by older siblings when speaking to their younger siblings about unobservable entities. Method Participants A total of 16 sibling pairs participated in this study. Each sibling pair consisted of a younger sibling aged 3 to 6 years ( range = 3;3-6;7; mean age = 5;3), and an older sibling 6 to 10 years of age (range = 6;11-10;7; mean age = 8;3), with an average difference in age of 3;5. The sibling dyads were drawn from the same community sample in Massachusetts as the first study. Nine older brothers and seven older sisters talked to their younger siblings in the current study. Of the 16 dyads, eight pairs of siblings were of the same gender: five pairs of brothers and three pairs of sisters. Procedure A procedure similar to that used in Study 1 was employed in Study 2. Both siblings received small prizes for their participation. The older siblings in each dyad were asked to teach their younger sibling about topics in the same categories as the parent-child pairs in Study 1. Older siblings were specifically asked to teach their younger siblings because pilot data showed that this helped the sibling pairs stay on topic in their conversations. To ensure that the older siblings had some knowledge of all of the topics, those in the historical figures category were different from the topics presented to the parent-child D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 23 dyads in Study 1. Specifically, Mother Theresa, John F. Kennedy, and Princess Diana were replaced with Rosa Parks, George Washington, and Betsy Ross. All conversations were videotaped and transcribed for coding. Coding The coding procedures used in Study 2 were identical to those used in Study 1. Reliability of coding was conducted on 31.25% of the transcripts. Cohen’s Kappa fell within the acceptable range for coding in the Scientific (.67), Historical (.82), Endorsed (.87), and Non-Endorsed (.67) categories. Results Siblings’ conversations were significantly shorter than parent-child conversations (t(61) = 2.37, p < .05, d = 0.75), but the proportion of time spend on each topic did not differ between the parents and siblings. Table 4 presents more descriptive statistics about siblings’ conversations. Like parents, older siblings were most likely to explicitly deny the existence of non-endorsed entities (see Figure 2). A Firth logistic regression was used because no siblings denied the existence of scientific or historical entities, creating a separation issue. This procedure indicated that topic category explained a significant portion of the variance in older siblings’ endorsement or denial of the existence of an entity, Ȥ2(3) = 15.91, p < .01. Further, older siblings were significantly more likely to deny the existence of non-endorsed entities than scientific entities (ȕ = 3.73, p < .001), historical figures (ȕ = 3.73, p < .001), and even endorsed entities (ȕ = 1.51, p < .05). D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 24 In conversations with older siblings, younger siblings rarely mentioned the reality status of the entities discussed. No younger siblings spontaneously spoke about the reality status of scientific entities or historical figures, while one child (6.25%) mentioned it for endorsed entities, and two (12.5%) talked about the reality of non-endorsed entities. There were no significant differences in younger siblings’ talk about reality status across categories. Repeated measures ANOVAs revealed some differences in the content of siblings’ conversations across the four topic categories, and all ANOVA results are reported in Table 5. Older siblings varied significantly in their discussion of both physical and internal features across categories. Planned Scheffe pairwise comparisons revealed that older siblings were much more likely to talk about the physical features of non-endorsed entities (M = 3.00, SD = 2.78) than of historical figures (M = 0.19, SD = 0.54) or scientific entities (M = 0.69, SD = 1.30). Like parents, it seems, older siblings focused on physical descriptions of non-endorsed entities, rather than using other cues. Older siblings also differed in talk of consensus across the topic categories. Planned Scheffe pairwise comparisons indicated that they demonstrated a lack of consensus significantly more often when speaking about endorsed entities (M = 0.63, SD = 0.89) than they did when speaking about historical entities (M = 0.0, SD = 0.0) or scientific entities (M = 0.0, SD = 0.0). Just like parents, by qualifying their discussions of endorsed entities in this way, older siblings may indicate to young children that these beings are somehow different from other, real entities. D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 25 Discussion The substance of siblings’ explanations, similarly to parents’ conversations, varied most when speaking about non-endorsed entities. They often explicitly denied the existence of non-endorsed entities, enabling young children to confidently report that these entities are not real. On the other hand, when older siblings told young children about scientific entities, historical figures, and endorsed beings the content of their testimony remained relatively constant. Older siblings did provide one important pragmatic cue—namely, their indications of a lack of consensus on a topic—to differentiate their conversations about endorsed beings. This may contribute to young children’s less confident but distinct conceptualizations of real and endorsed entities, in much the same way the properties of parent testimony do. When considered with the results of the first study, these findings suggest that there is merit in the testimony hypothesis. The conversations young children have about unobservable entities vary in several types of discourse cues, present in both the information they hear and in how that information is communicated. Further, we find that conversations with various important others in a young child’s environment, including both parents and older siblings, seem to vary in the same types of ways. Exposure to these cues may affect the way in which children conceptualize different unobservable entities. GENERAL DISCUSSION D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 26 The results of the current research indicate that the testimony children receive about unobservable entities in naturalistic settings varies with respect to the type of entity discussed, and that both parents and older siblings provide young children with cues that signal the veridical nature of the entity they are talking about. Thus, these findings provide evidence for the first assumption of the testimony hypothesis, and suggest that such differences in the speech children hear may in fact impact their conceptions of the unseen world. Both parents and older siblings were likely to affirm the existence of entities in the scientific and historical categories, and were most likely to deny the existence of non- endorsed entities. Further, older siblings were just as likely to affirm the existence of endorsed entities as they were to affirm scientific and historical ones. Parents, on the other hand, were more likely to deny that those entities exist. In spite of this difference, parents spoke about scientific and endorsed entities so similarly that discussions in these categories could be clustered together for analysis. On the other hand, both parents and siblings spoke about non-endorsed entities much differently than other entities. For instance, their conversations about non-endorsed entities were more superficial than their talk about either scientific or endorsed entities, emphasizing the non-endorsed entities’ physical features. Although the parent-child and sibling conversations about scientific and endorsed entities were quite similar, subtle distinctions were found between discussions in these two categories. Parents and siblings were much more likely to indicate a lack of consensus or D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 27 expertise when talking about endorsed entities than they were when talking about scientific entities. In addition, parents used physical demonstrations more often when talking about scientific entities than they did when talking about endorsed entities. Previous work has found that young children categorize and conceptualize different types of unobservable entities differently (Sharon and Woolley, 2004; Harris, Pasquini, Duke, Asscher, & Pons, 2006). Harris and colleagues (2006) have proposed that these differences may be due to variations in the testimony children hear from adults and important others, and subsequent work has indicated that children can use speech cues to an entity’s reality status in experimental procedures (Woolley & Ma, 2009). The present study examined a primary tenet of the testimony theory—whether cues like the ones used in experimental designs actually occur in conversations that young children have. The current findings indicate that, in fact, these types of cues are present in naturalistic conversations, and therefore provide further evidence for the testimony hypothesis. Thus, the confident distinctions children make between which entities they believe are real and which they do not may stem from differences in the content of the testimony of others. Nevertheless, it seems that the real variations in children’s conceptions of unobservable entities—those seen when they are asked to make more fine-grained distinctions—may be based on the pragmatic cues in the testimony they hear rather than on explicit content. Older siblings and parents often indicated a lack of consensus when talking about endorsed figures, and previous research has demonstrated that young children can use this cue when deciding whether or not to trust others’ testimony (Corriveau, Fusaro, & Harris, 2009). D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 28 Further, parents also often conveyed a lack of expertise about endorsed entities, expressing doubts in the existence of and their lack of knowledge about such entities. Lack of confidence in one’s knowledge is a cue that children have been shown to use when assessing the quality of others’ testimony (Jaswal & Malone, 2007), but it has not been explored in the context of testimony about unobservable entities. Although most parents encourage belief in many endorsed entities, conveying a lack of expertise when talking about endorsed figures may invite children to think critically about these entities, or to show uncertainty themselves when asked about the nature of such beings. Because we wanted to make sure the conversations included in the current study were as naturalistic as possible, no time limits were placed on the discussions, and experimenters were not present while the dyads talked, so there was no ability to keep conversations on the topics of interest. Thus, the conversations examined were relatively short and the mean frequencies of many types of discourse cues were low. Despite this, the differences in the mean frequencies of cues between the different categories of entities may be important, because children are exposed to many similar conversations in their day-to- day lives. So, although the differences between cues in one conversation may be small, continued experience with these sorts of cues can have a broader effect. This clearly seems to be the case when the present results are considered in the context of previous research showing that children are sensitive to cues manipulated in an experimental context (Harris et al., 2006; Woolley, Ma, & Lopez-Mobilia, 2011). D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 29 Future research should focus specifically on differences in parents’ explanations about different types of endorsed entities. The present results indicate that parents provide less confident explanations about endorsed entities than they do about real entities. However, in previous studies, parents have reported that they would be more confident when speaking with their preschoolers about some endorsed entities than they would be when talking about other topics in the same category (Rosengren & Hickling, 1994). Because in the current research parents were allowed to choose which topic in the endorsed category to explain, the present results are not suited to analyze differences in talk about different endorsed entities. It is possible that if such differences were displayed in parents’ conversations, they may lead children to differential beliefs between, for instance, religious entities and event-related fantasy entities. Future research may also examine the conversations young children have with teachers, peers, and other significant people in their lives. This would provide a more complete picture of the ways in which the testimony children receive varies both between categories of unobservable entities, and between the people with whom they converse. Finally, studies in the future could determine whether socioeconomic status plays a role in the way parents speak with their children about unobservable entities. There is evidence from previous research that middle-class mothers tend to speak about non- present objects and people more often than working-class mothers do (Tizard & Hughes, 2002), and so their children may have different levels of experience in decoding the types of cues found in the current study. This could have implications for children’s later scientific thinking because, according to many researchers, children’s learning about D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 30 science begins in informal settings, such as in conversations with family members (Ash, 2003; Callanan & Jipson, 2001; Ellenbogen, 2002; Leinhardt & Crowley, 2002). By the time they start school, children have spent hours engaged in conversations with adults and have already learned to make inferences about entities that they cannot experience directly. However, if differences exist in the conversations children of different socioeconomic statuses have, their ability to draw these inferences may be affected. The present research provides empirical evidence for the existence of important variations in the naturalistic verbal input that children receive about different types of unobservable entities. This is consistent with the proposal that children’s beliefs about the unseen world (including both real and fantastical entities) are shaped in important ways by the testimony that they receive from others. The current results also show that others’ speech varies both in content and pragmatics across different types of unobservable entities and that children are likely to be exposed to such variations in everyday conversation about a variety of topics. The present study did not empirically connect variations in testimony to children’s conceptions of such entities, both because of the semi-naturalistic nature of the study, and because children had previous knowledge of most of the entities discussed. Further research examining whether differences in the testimony children hear are reflected in their categorization and description of unseen entities should provide important information about how children structure their knowledge about unobservable entities. D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 31 This research shows that others’ testimony may play a crucial role in this process, and supports the validity of the last unresolved assumption of the testimony hypothesis. #ACKNOWLEDGEMENT The authors would like to thank the families who participated in this study. We also thank Martyna Galazka, Carina Wind, and Amanda Rhoads for their help in this research, and Paul Harris for his insightful comments on early versions of this manuscript. REFERENCES Ash, D. (2003). Dialogic inquiry in life science conversations of family groups in a museum. Journal of Research in Science Teaching, 40, 138-162. doi: 10.1002/tea.10069 Azmitia, M., & Hesser, J. (1993). Why siblings are important agents of cognitive development: A comparison of siblings and peers. Child Development, 64, 430-444. doi: 10.2307/1131260 Callanan, M., & Jipson, J. (2001). 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Young children’s understanding of the fantasy/reality distinction. British Journal of Developmental Psychology, 22, 293- 310. doi:10.1348/026151004323044627 Tizard, B., & Hughes, M. (2002). Young Children Learning (2nd ed.). London: Fontana Paperbacks. Woolley, J., & Ma, L. (2009). Children’s use of conversational cues to infer reality status. Paper presented at the Biennial meeting of the Society for Research in Child Development, Denver, CO. Woolley, J., Ma L., & Lopez-Mobilia, G. (2011). Development of the use of conversational cues to assess reality status. Journal of Cognition and Development, 12, 537-555. doi: 10.1080/15248372.2011.554929 D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 35 Table 1. Examples of Coded Statements. Discourse Cue Example Action "And Mermaids swim. Do you know why?" Physical Feature "I think [dragons] are usually green." Internal Feature "Mother Theresa was a very nice lady..." Location "Where in your body is your brain? Can I show you…It's inside [your head]." Related Action "When you lose a tooth, you put it under your pillow…" Lack of Expertise “Well, we don’t actually know this but I think he’s really big” Lack of Consensus “Some people think [God] is like this big guy, up in the sky…” Example "…the lights are electric. What about our stove?" Analogy "Mother Theresa was a nun, like Sister Lois at our church." Demonstration Indicating one end of table: "North America is here," Sliding hand across table: "and then there's the Atlantic Ocean," Indicating other end of table: "and then over here is Europe." D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 36 Table 2. Descriptive statistics of conversations (Study 1). Topic % of Conversations Mean Time Endorsed Category Tooth Fairy 40.4% 2:43 Santa Claus 27.7% 3:03 Easter Bunny 14.9% 2:50 God 17.0% 1:39 Non-Endorsed Category Unicorns 25.5% 2:31 Witches 17.0% 2:15 Mermaids 29.8% 1:45 Dragons 27.7% 3:27 Historical Category Christopher Columbus 36.2% 2:09 Mother Theresa 14.9% 2:02 Princess Diana 34.0% 2:55 John F. Kennedy 14.9% 2:23 Scientific Category Brain 23.4% 2:03 Germs 40.4% 3:14 Magnetism 17.0% 2:45 D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 37 Electricity 19.2% 1:51 D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 38 Table 3. Repeated Measures ANOVA for discourse cues across cluster (Study 1) Cue Type df F Ș2‡ Action 1.72† 7.88* 0.15 Physical Feature 1.46† 39.13* 0.46 Internal Feature 1.68† 0.63 0.01 Location 2 3.95* 0.08 Related Action 2 8.63* 0.16 Lack of Expertise 1.54† 2.38 0.05 Lack of Consensus 1.63† 2.63 0.05 Example 1.55† 9.21* 0.17 Analogy 2 4.06* 0.08 Demonstration 1.53† 0.25 0.01 ‡ Cohen (1988) provides suggested f values for small, medium and large effect sizes for ANOVA, as well as conversions from Ș2 to f. These conversions yield estimates of small, medium, and large effect size values for Ș2 of .01, .06, and .14, respectively. † Greenhouse-Geisser corrected * p < .01 D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 39 Table 4. Descriptive statistics of conversations (Study 2). Topic % of Conversations Mean Time Endorsed Category Tooth Fairy 12.5% 1:52 Santa Claus 37.5% 1:45 Easter Bunny 12.5% 1:22 God 37.5% 1:07 Non-Endorsed Category Unicorns 18.8% 0:34 Witches 12.5% 1:14 Mermaids 31.3% 1:15 Dragons 37.5% 2:33 Historical Category Christopher Columbus 12.5% 1:31 Rosa Parks 18.8% 1:56 Betsy Ross 0.0% 0:00 George Washington 68.8% 1:10 Scientific Category Brain 18.8% 1:57 Germs 43.8% 1:23 Magnetism 6.0% 1:40 D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 40 Electricity 31.3% 2:29 D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 41 Table 5. Repeated measures ANOVA for discourse cues across category (Study 2). Cue Type df F Ș2 Action 3 1.84 0.11 Physical Feature 1.71† 5.50* 0.27 Internal Feature 1.96† 3.50 0.19 Location 3 0.82 0.05 Related Action 2.14† 1.95 0.12 Lack of Expertise 2.13† 2.37 0.14 Lack of Consensus 1.75† 5.87* 0.28 Example 2.01† 3.51 0.19 Analogy 1.79† 3.00 0.17 Demonstration 1.12† 2.45 0.14 † Greenhouse-Geisser corrected * p < .05 D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 42 Figure 1. Number of parents who affirmed or denied the existence of entities in each category. D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT 43 Figure 2. Number of older siblings who affirmed or denied the existence of entities in each category. D ow nl oa de d by [U ni ve rs ity o f T or on to L ib ra ri es ] a t 1 3: 08 2 2 A pr il 20 13 work_3ttrf3euejbfnh4xeeb2fviggq ---- ‘The Mona Chronicle’: the archaeology of early religious encounter in the New World Jago Cooper1, Alice V.M. Samson2, Miguel A. Nieves3, Michael J. Lace4, Josué Caamaño-Dones5, Caroline Cartwright6, Patricia N. Kambesis7 & Laura del Olmo Frese8 The Caribbean island of Mona, on a key Atlantic route from Europe to the Americas, was at the heart of sixteenth-century Spanish colonial projects. Communities on the island were exposed to the earliest waves of European impact during a critical period of transformation and the forging of new identities. One of many caves within an extensive subterranean world on the island was marked both by indigenous people and by the first generations of Europeans to arrive in the New World. This account of spiritual encounters provides a rare, personalised insight into intercultural religious dynamics in the early Americas. Keywords: Caribbean, Isla de Mona, cave art, finger-fluting, inscription, iconography, religion, Christianity Introduction Isla de Mona in the Caribbean preserves some of the most astonishing and under-researched evidence for indigenous-European interaction in the Americas. The archaeology of the 1 British Museum, Americas Section, Great Russell Street, London WC1B 3DG, UK (Email: jcooper@ britishmuseum.org) 2 School of Archaeology and Ancient History, University of Leicester, Leicester LE1 7RH, UK 3 Departamento de Recursos Naturales y Ambientales, Bureau of Coasts, Reserves and Refuges, Rı́o Piedras 00906, Puerto Rico 4 University of Iowa, Coastal Cave Survey, West Branch, IA 52242, USA 5 Universidad de Puerto Rico Rı́o Piedras, Centro de Investigaciones Históricas, San Juan 00931, Puerto Rico 6 British Museum, Department of Scientific Research, London WC1B 3DG, UK 7 Western Kentucky University, Department of Geography and Geology, Bowling Green, KY 42101, USA 8 Instituto de Cultura Puertorriqueña, Programa de Arqueologı́a y Etnohistoria, San Juan 00902, Puerto Rico C© Antiquity Publications Ltd, 2016. This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-nc- nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is unaltered and is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use or in order to create a derivative work. ANTIQUITY 90 352 (2016): 1054–1071 doi:10.15184/aqy.2016.103 1054 mailto:jcooper@britishmuseum.org mailto:jcooper@britishmuseum.org http://creativecommons.org/licenses/by-nc-nd/4.0/ http://creativecommons.org/licenses/by-nc-nd/4.0/ http://dx.doi.org/10.15184/aqy.2016.103 R es ea rc h The Mona Chronicle island’s caves provides an opportunity to study personal responses to an indigenous ritual landscape through evidence of the early translocation of Christianity to the New World. This article discusses a body of uniquely preserved inscriptions and iconography that captures the intimate dialogue of spiritual encounter between Christian and Native worldviews in the Caribbean. This unique and unorthodox ‘chronicle’ is examined through the archaeological, palaeographical and historical perspectives of early colonial encounters to situate the dialogue within the wider context of cultural interaction in the Americas. The transformative potential of an archaeological perspective of the early arrival of Europeans and Africans in the indigenous Americas has become increasingly evident since the quincentennial of Columbus’s landfall in the Caribbean (Lightfoot 1995; Deagan 1998; Liebmann & Murphy 2011; Funari & Senatore 2015). Archaeological research has focused on indigenous perspectives that are under-represented in historic texts, breaking down traditional dichotomies of what ‘indigenous’, ‘Spanish’ or ‘mestizo’ means in colonial contexts in terms of material culture, landscape and identities (Voss & Casella 2012; Hofman et al. 2014; Silliman 2015). Increasing use of high-resolution material and archaeometric analyses have provided new understandings of colonial processes that are more nuanced than mere oppression, domination and, in the case of the Caribbean, indigenous extinction (Deagan 1998; Lalueza-Fox et al. 2003; Cooper et al. 2008). Archaeological perspectives on the ways that colonialism reconfigures landscapes and material relationships (Gosden 2004) reveal the forging of new material relationships and identities, be it in the re-use of European clothing and fastenings as jewellery by indigenous populations (Martinón- Torres et al. 2007; Valcárcel Rojas 2016); the creolisation of religious beliefs in newly built churches (Graham 2011); or coloniser familiarisation with new environments, foodways and ecologies (Deagan & Cruxent 2002; Rodŕıguez-Alegŕıa 2005). These each demonstrate that encounter left all sides changed: new identities and practices emerged in local contexts, underlining the importance of archaeological research to provide a counterpoint to grand narratives (Voss 2015). Here, we focus on archaeological evidence for religious engagement between European and indigenous individuals. We see how European perspectives were challenged by indigenous cosmology, and witness the creation of a highly personalised yet syncretic chronicle. This not only provides a counterpoint to official metropolitan histories, but also tracks the beginnings of new religious engagements and transforming cultural identities in the Americas. Isla de Mona Christopher Columbus stopped at Isla de Mona on his second voyage in AD 1494 (Figure 1). Despite its small size (50km2) and seemingly isolated position between the islands of Hispaniola (native name Hayti) and Puerto Rico (Borinquen), Isla de Mona (Amona) played a crucial role in the establishment of the first European towns and the globalisation of the Caribbean. In AD 1494, one or more indigenous communities lived on Mona’s coast, a day’s canoe journey from the neighbouring, larger islands, tending agricultural plots and taking advantage of the abundant terrestrial and marine resources. Stone-lined plazas and a long history of the use of the island’s many caves indicate that these communities were tied into inter-regional networks (Dávila Dávila 2003; Samson & Cooper 2015a). C© Antiquity Publications Ltd, 2016 1055 Jago Cooper et al. Figure 1. Map of Isla de Mona in the Caribbean. Accounts of Mona in early colonial documents (Samson & Cooper 2015b) identify that indigenous populations were fully immersed in direct contact with Europeans and Africans throughout the sixteenth century. This indio population experienced a generation of transformation as Spanish power was increasingly projected into the Caribbean. Islanders produced and exported agricultural products, especially cassava bread, and finished goods such as cotton shirts and hammocks for the first Spanish settlements, increasingly supplying food and water to European ships on their way to or from the Indies (Murga Sanz 1960; Wadsworth 1973; Cardona Bonet 1985). Mona’s location in the heart of Spanish colonial projects, and on one of the main Atlantic routes from Europe to the Americas, allowed inhabitants to exploit the opportunities of this early colonial world. Communities on Mona were exposed to the earliest waves of European impact at a time when Europeans themselves were in an alien environment, gathering knowledge, making decisions and learning patterns of behaviour that became more firmly entrenched as the colonisation of the Americas contin- ued. This was a critical period of creolisation in which the first and subsequent generations of inter-continental Americans were born; there is therefore great potential for the archaeology of Mona to provide insights into the transformation and forging of new identities. Indigenous Amona Archaeological evidence of an indigenous presence on Mona spans over 5000 years (Dávila Dávila 2003; Samson & Cooper 2015b). The population that witnessed Columbus’s ships was part of a large, complex cultural network of territorially, genetically, linguistically and artistically interwoven chiefdoms stretching from the Bahamas to the Lesser Antilles, with some population estimates for Hispaniola alone of over one million people, and for Puerto Rico of 100 000 (Anderson-Córdova 1990; Rouse 1992; Moscoso 2008). During C© Antiquity Publications Ltd, 2016 1056 R es ea rc h The Mona Chronicle Figure 2. Early colonial Nueva Cadiz bead discovered at Playa Sardinera on Isla de Mona. later pre-Columbian times, from AD 500, Mona was a hub of interaction between the chiefdoms of Borinquen and Hayti. From AD 1300–1500, a spike in evidence for cave exploration suggests the island’s subterranean spaces were a major draw; cave practices were instrumental in late pre-Columbian ethnogenesis. The earliest Spanish accounts of Mona emphasise Spanish dependence on indigenous labour and products (Fernández de Oviedo y Valdéz 1851: 16: 1; Samson & Cooper 2015b). European encounter on Mona The adoption of European material culture, products and technology on Mona was immediate and profound. During recent fieldwork, European objects recovered within indigenous settlements and activity areas include glass beads (Figure 2), new types of European storage jars, ceramic vessels and monetary currency at sites along the south coast and inland. Imports spanning the period from AD 1493–1590 are found in residential settlements, agricultural fields and cave refugia. The presence of European ceramics and livestock, and Spanish coins in direct association with indigenous ceramics, tools and food- processing equipment, reflects this changing material world and indigenous transculturation (Dávila Dávila 2003; Cooper et al. 2008). As a counterpart to technological and economic transformation, however, the subterranean landscape of Mona reveals extraordinary material evidence of the face-to-face ontological encounter, providing a window into the spaces and experiences of the spiritual transformation. Caves of Mona Isla de Mona is one of the most cavernous regions, per square kilometre, in the world (Frank et al. 1998). Limestone cliffs dominate, providing access to the island’s 200 Pliocene-era cave C© Antiquity Publications Ltd, 2016 1057 Jago Cooper et al. Figure 3. Indigenous iconography from cave 18 showing ancestral beings and anthrozoomorphic figures. systems in the geological interface between the hard, lower Isla de Mona Dolomite and the porous, upper Lirio Limestone (Kambesis 2011; Lace 2012, 2013). The caves exponentially increase the experience of the island’s size, providing access to a subterranean realm that is often more easily traversed than the densely vegetated world above. Caves on Mona provide a palimpsest of human activity spanning the pre-Columbian past to the present day, with clearly identifiable peaks in human cave use (Samson et al. 2015). The importance of caves within the spiritual or, from a European perspective, ‘religious’ framework of indigenous populations across the Americas is well established (Brady & Prufer 2005; Moyes 2013). In the Caribbean, late-fifteenth-century accounts collected from indigenous informants on Hispaniola relate the emergence and origins of the first humans from two separate caves (Pané 1999). Indeed, archaeological evidence from across the archipelago shows that caves were used for purposes such as the deposition of human remains and social valuables, and as locations of symbolic iconography. Since 2013, archaeological survey of around 70 cave systems—part of an interdisciplinary study of past human activity on Isla de Mona—has revealed that Mona’s caves provided a range of symbolic, economic and subsistence resources to residents and visitors, and to indigenous and historic populations. Indigenous presence has been identified in 30 cave systems around the island. Evidence includes the greatest diversity of preserved indigenous iconography in the Caribbean, with thousands of motifs recorded in darkzone chambers far from cave entrances (Lace 2012; Samson et al. 2013; Samson & Cooper 2015b). Marks consist of geometric motifs, meanders and areas where the soft cave crusts have been deliberately and systematically removed, as well as extensive and complex imagery of anthrozoomorphic and ancestral beings (cemı́es) (Figure 3). Cave chambers both large (>50m in diameter) and small (<1m wide), their surfaces covered with iconography, must C© Antiquity Publications Ltd, 2016 1058 R es ea rc h The Mona Chronicle Figure 4. Indigenous mark-making and its relation to sources of water in chamber E. have been a unique architectural experience for indigenous populations, and very different from the biodegradable and permeable domestic architecture of their settlements (Cooper et al. 2010; Samson 2013). As well as being symbolic locations, caves on Mona contain important subsistence resources, such as the only sources of permanent fresh water. There is a clear association between underground sources of fresh water and concentrations of indigenous mark-making (Lace 2012). The role of the caves as a source of life-giving water is referenced in the iconography (Figure 4). The markings on the cave walls and extraordinary acoustic, olfactory and haptic properties of the environment offer a powerful experience of alterity, enhanced by the lack of usual sensory stimulation, disorientating and heightening awareness, and morphing perspectives of space and time (Siffre 1964). Hundreds of metres underground, torch or lamplight flickering across representations of cemı́es on walls and ceilings, some reflected in pools of water, would have made a powerful impression on all visitors to the caves. C© Antiquity Publications Ltd, 2016 1059 Jago Cooper et al. Figure 5. Indigenous ceramics from cave 18 with similar iconography from cave 12 on the other side of the island. Cave 18 In this paper, we focus on archaeological, chronometric, palaeographical and historical evidence for a series of early to mid-sixteenth-century cave visits that illuminate previously unknown aspects of the indigenous-European spiritual encounter. Cave 18 is on the south coast of Mona, reached by traversing the foot of a cliff, climbing a vertiginous cliff face and scrambling through a human-sized entrance. Chambers and tunnels run for more than 1km. Around half a dozen balcony entrances in the cliff face provide access to dendritic pathways leading back to deep, darkzone cave chambers. Tunnels emerge into a series of low rooms, high vaulted chambers and areas of water pools and flowstone. After around 50m of walking, in darkness, one encounters the material record of indigenous, followed by historic, mark-making. Indigenous mark-making Evidence of indigenous activity occurs within a large yet delimited darkzone area in chambers A–K (Figures 3 & 4). Around 250 separate motifs, made by dragging one to four fingers (‘finger-fluting’), and finger-sized tools through the soft deposits of the cave surfaces, cover the walls, ceilings and alcoves in 10 chambers and interconnecting tunnels over some 6500m2— about 15 per cent of the cave system. Execution of the imagery necessitated climbing and crouching to reach desired surfaces. The indigenous origin of the marks is supported by the clearly identifiable styles of Late Ceramic Age iconography, as well as from Capá (thirteenth- to sixteenth-century) pottery found in the same chambers (Figure 5). Two radiocarbon dates (OxA-31209 & OxA-31536) from charcoal (Amyris elemifera and Bursera simaruba) recovered from untrammelled edges of two separate chambers (Figure 6) date to C© Antiquity Publications Ltd, 2016 1060 R es ea rc h The Mona Chronicle Figure 6. Map of cave 18 showing the locations and spatial relationships between the indigenous iconography and post-contact inscriptions. the fourteenth and fifteenth centuries (1272–1387 cal AD, and 1420–1458 cal AD at 95.4% confidence, in Oxcal v4.2, using IntCal13 (Bronk Ramsey 2009; Reimer et al. 2013)). Historic mark-making More than 30 historic inscriptions in cave 18 include phrases in Latin and Spanish, names, dates and Christian symbols that occur within a series of connecting chambers (Figure 6), all within the area of indigenous iconography. Where both occur together, the average height above the floor of the historic marks is 1.8m, compared to 1.5m for indigenous marks. There are no indigenous marks overlaying written inscriptions or Christian symbols. The majority of the inscriptions are single-lined strokes, created by a variety of edged tools, and thus distinct from the finger-fluted indigenous marks. The Christian imagery and inscriptions are predominantly at or above (European) head height, occupying flat, vertical wall surfaces and visible while walking upright through the space, distinct from the lower positions and multiple orientations of indigenous marks. C© Antiquity Publications Ltd, 2016 1061 Jago Cooper et al. Figure 7. Spanish inscription in cave 18 that reads ‘dios te perdone’, God forgive you. Three inscribed phrases are present in chambers H and K: ‘Plura fecit deus’, ‘dios te perdone’ and ‘verbum caro factum est (bernardo)’. Palaeographic analysis of letter forms, the use of abbreviation and writing conventions place these in the sixteenth century (Samson et al. in press). ‘Plura fecit deus’, or ‘God made many things’, is the first inscription encountered after entering chamber H. There is no obvious contemporary textual source; the commentary appears to be a spontaneous response to whatever the visitor experienced in the cave. There is a strong spatial inference that ‘things’ is a reference to the extensive indigenous iconography present. The phrase may express the theological crisis of the New World discovery, throwing the personal human experience and reaction into sharp relief. In the next chamber, the phrase ‘dios te perdone’, ‘may God forgive you’, is inscribed on a ceiling protuberance surrounded by extensive indigenous finger-fluting (Figure 7). This is a common Christian petition, which implies a separation between the author and the subjects, or acts that require forgiveness, and the intercessional role of the author, perhaps akin to a confessional pardon between priest and sinner. Another implication is that the attendant practices, now invisible to us, require forgiveness as well as the images themselves. The third Latin inscription, ‘verbum caro factum est’, is a direct quotation from the Vulgate version of the bible, the Gospel of John 1:14, “And the Word was made flesh [and dwelt among us]”. The biblical passage follows a description of the creation of the world, and is the first announcement of Jesus (the Word) in the Gospel, followed by his baptism. This well-known chapter of the Bible would have been familiar even to Christians without formal Latin education (Richard Rex, pers. comm. 2015). C© Antiquity Publications Ltd, 2016 1062 R es ea rc h The Mona Chronicle Figure 8. A Christian Calvary in cave 18 with the name Jesus under the central cross. Particularly striking are two depictions of Calvary. The first consists of three crosses, the central one with the Latin inscription ‘Iesus’ (Jesus) set at a height of over 3m in chamber G (Figure 8). Stylistically, all three are barred cross-on-base motifs, in use in the sixteenth century; similar examples are found from contemporary contexts in Europe and South America (McCarthy 1990; Hostnig 2004; Barrera Maturana 2011; Tarble de Scaramelli 2012). A second Calvary panel is made up of two crosses, one of which is a barred cross-on-base, the other a simple two-stroke Latin cross. These flank a pre-existing C© Antiquity Publications Ltd, 2016 1063 Jago Cooper et al. Figure 9. Selection of three Christian crosses found in cave 18 with stroke directions indicated. indigenous anthropomorphic figure. This triptych has clear compositional parallels with representations of Calvary in which the central figure is strikingly cast as an indigenous Jesus. Reinforcing the distinctly Christian character of the inscriptions are a series of 17 crosses, ranging from simple Latin crosses to more complex Calvary crucifixes (Figure 9). Crosses appear alone and in direct association with names and phrases, and most often close to indigenous finger-fluting and iconography. Analyses of stroke sequences demonstrate that the vertical line is drawn first, then the horizontal line added from left to right, in the gesture of a right-handed blessing. Crosses are placed in visually dominant positions over cave entrances or on high walls, most being set vertically above indigenous iconography rather than superimposed. This vertical ordering is a clear and cross-culturally understood visual convention of hierarchical relations, and seen elsewhere in rock art sites across the Americas (Hostnig 2004; Mart́ınez Cereceda 2009; Tarble de Scaramelli 2012; Recalde & González Navarro 2015). Although indigenous cross motifs are common across the Antilles and Andean region, these are distinct, often framed, equal-armed crosses, produced in a different way in terms of directionality, style, method and location (Dubelaar 1986: 102). Simple crosses are also found adjacent to a series of Christograms (Figure 10), abbreviated forms of the name of Jesus Christ, which had been in use for over a millennium when these examples were incised in the walls of the cave. The Christograms employed on Mona used Latin and Greek characters to form a symbology of Christ’s name, and these were in C© Antiquity Publications Ltd, 2016 1064 R es ea rc h The Mona Chronicle common usage from early medieval periods. The simplest form found in cave 18 is IHS, the first letters of Jesus in the Greek alphabet. A more complex form is the abbreviated Figure 10. An IHS Christogram that uses the first three letters of Jesus in the Greek alphabet to reference Jesus Christ. form of ‘Jesus’, ‘IHS’, followed by a cross and then ‘XPS’, or chi-rho-sigma for ‘Christ’. In all cases, the ‘H’ has a cross above it, also common in late medieval Christograms. The name of Christ engraved into the walls of the cave materialises a Christian characterisation of the space. The dominance of the Christ figure (as opposed to Mary or another saint) confers a Christocentric devotional character that was rooted in late medieval tradition and became increasingly popular in New World shrines throughout the sixteenth and seventeenth centuries (Nolan 1991; Taylor 2010). In addition to Christian symbolism and religious commentary, the cave walls also bear a series of dated and named individuals. These include Myguel Rypoll 1550, Alonso Pérez Roldan el Mozo 1550 August and Alonso de Contreras 1554. Other sixteenth-century visitors include a canon (an ecclesiastical office), an individual named Bernardo, who added his name to the inscription ‘verbum caro factum est’ and an anonymous visitor in February 1554. A Capitán Francisco Alegre wrote his name prominently in chamber K. Archival research Many of the names on the cave surfaces are not listed in the official texts referring to the initial Spanish occupation of Mona. Searches of the early colonial chronicles, passenger lists to the Indies from 1500–1590, relevant sections of the digitised archives of Seville, and the Documentos de la Real Hacienda de Puerto Rico were consulted for individuals with connections to Mona, including the Baptismal-indigenous name combinations and Spanish rank titles of over 100 indios. The most secure identification is for Francisco Alegre, who has been identified in historical documents—and on the basis of handwriting similarities (Figure 11)—as having emigrated with his father to the Indies in the 1530s from Spain. Alegre became a prominent citizen (vecino) of San Juan and held a number of royal functions in Puerto Rico throughout the sixteenth century, including that of factor, in charge of royal estates, among which was Isla de Mona (Archivo General de Indias 1550). C© Antiquity Publications Ltd, 2016 1065 Jago Cooper et al. Figure 11. The name of Capitán Francisco Alegre, royal official of Puerto Rico in the mid-sixteenth century; note the similarities between the writing on the cave wall and his name in an archival manuscript from AD 1550. Discussion—‘The Mona Chronicle’ In the sixteenth century, the persistence of Mona’s indio population, their relative autonomy and the island’s geopolitical position in a trans-Atlantic and Caribbean maritime thoroughfare created the conditions for a century of spiritual encounter. The corpus of post-contact inscriptions and their physical interrelationship with indigenous iconography and practices strongly suggests authorship by people of European descent visiting Isla de Mona from the neighbouring Spanish colonies of Puerto Rico and Hispaniola. The position, relative sequencing, production methods, written dates and content of the mark-making, as well as the biographic identification of Francisco Alegre, support this interpretation. Indigenous iconography, ceramics and two radiocarbon dates indicate that the cave was used by indigenous people during the mid fifteenth century, directly preceding European arrival. The presence of a historically documented church in the Sardinera village in AD 1548 (Dávila Dávila 2003: 33), administered by indigenous converts, suggests that indigenous Christians were themselves directly engaged with this arrival of a new ideology and associated visual culture. It is possible that some of the finger-drawn crosses in cave 18 may have been executed by indios conversos (indigenous peoples converting to Christianity), as has been proposed for the colonial Andes (Hostnig 2004). Further research will consider whether at least some of the historic inscriptions and names may belong to indigenous individuals. Certainly, access to both the cave and the relevant chambers necessitated preparation and knowledge of local geography. The presence of over half a dozen named individuals, different dates and the diversity of handwriting indicates multiple visits over time, most notably in the 1550s. The fact that cave 18 was singled out from the nearly 30 currently known caves with indigenous activity on Mona implies that it was an established and meaningful indigenous space at the time of contact, and this was the impetus for its continued use into colonial times. C© Antiquity Publications Ltd, 2016 1066 R es ea rc h The Mona Chronicle New generations of Americans of diverse cultural heritage began to differentiate themselves from the cultures of the European metropole, and new identities such as indio and creole are recognised as early as 1514 in historic records (Moscoso 2010). It is within this context that the first generation of Europeans and Christian indios from diverse American homelands visited Mona’s cave 18. At least some of the authors were elite males of Spanish ancestry, knowledgeable about certain aspects of indigenous culture, conversant with indigenous beliefs and willing to engage with them. The presence of a canon, and those with basic literacy and education, suggests both lay figures and church officials made journeys to the cave. One must consider the range of motivations for such visits. There were economic advantages to alliances with the indio community on Mona, which was still an important centre of cassava production in the second half of the sixteenth century. Similarly, indios may have gained economic and political advantages by pursuing alliances with vecinos such as Francisco Alegre. Beyond economic motivations, the construction of new colonial landscapes may have been related to the emergence of an indio converso identity, especially after the end of Spanish encomienda (where designated territories were given by the crown to individual European colonists to manage and administer) around 1546. Further, from a coloniser perspective, the founding of local Christian shrines was essential to carving out a local Caribbean identity, drawing on indigenous traditions, in line with a post-reformation trend for shrine formation (Nolan 1991; Coleman & Elsner 1995; Stopford 1999). The interaction between Christian commentary and indigenous imagery represents individual responses and a degree of mutual understanding, rather than a coherent programme or formal liturgy. Visitors engaged with cross-cultural preoccupations such as concepts of origins (expressed in phrases such as plura fecit deus), the afterlife (images of the crucifixion), the hierarchy of belief systems (the crosses on top of indigenous marks), and the place of the individual (names and dates). The emotional and theological character of the inscriptions is different from the censure of the inquisition in places such as contemporary Mexico, where the incorporation of indigenous iconography into a Calvary scene (Figure 12) would have been deeply heretical. Moreover, from an indigenous perspective, the lack of clear evidence for resistance, such as the depictions of cross-bearing Spanish horsemen from indigenous rock art in the Andes (Gallardo et al. 1990; Mart́ınez Cereceda 2009), and the lack of explicit continuity of traditional visual codes, points to a degree of ownership of new beliefs and practices. The historical legacy of 1492 fixates upon and fetishises the incompatibility of native and European worldviews, leading to a one-sided picture of the spiritual conquest of the Americas, exacerbated by native ‘extinction’ in the Caribbean. Moreover, the sheer continental scale of colonisation means that grand narratives dominate our image of encounter. The individual narrative of the people who actually made these encounters operate at a temporal resolution of minutes, hours and days as revealed within this cave. These experiences are what frame early colonial attitudes and create the pathways of encounter, not from indigenous and European perspectives, but from an emerging generation of Americans. The unorthodox ‘Mona Chronicle’, a multi-authored account of the spiritual encounter, provides a rare insight into intercultural religious dynamics in the early Americas. C© Antiquity Publications Ltd, 2016 1067 Jago Cooper et al. Figure 12. Christian cross in a niche of cave 18, directly facing an indigenous ancestral figure. Corollary In 1550, King Charles V of Spain presided over a theological debate in Valladolid (Las Casas- Sepúlveda debate) about whether the Indians of the New World had rational souls (Hanke 1974). In the same year, Alonso Pérez Roldan the Younger and Myguel Rypoll partook in a procession to a local shrine, etched their names onto the walls of a cave chamber and joined a debate in this cave about the compatibility of the Catholic God and ancestral spirits with the indios who led them there. The contrast between the formal, intellectual, metropolitan debate, immortalised in paper archives, and the dialogue between colonial individuals of diverse origins, materialised in stone, could not be greater. Nevertheless, both express the metaphysical schisms, anxieties, social experiments and transformations engendered on all sides by the European-American encounters (Hanke 1974; Boxer 1978). It is often said that there was no conclusive outcome to the Valladolid debate. Its Caribbean counterpart C© Antiquity Publications Ltd, 2016 1068 R es ea rc h The Mona Chronicle on the other hand, a personal debate reflected within the Mona Chronicle of cave 18, had some clearly identifiable outcomes with arguably one of the first manifestations of a creole Christian identity in the New World. These discoveries and their interpretation reveal a process by which new identities are forged in this greatest of cultural encounters, and they provide insight into the creation of new cultural identities throughout the Americas. Acknowledgements This research was conducted with the support of the British Museum Research Committee, the McDonald Institute for Archaeological Research (University of Cambridge), the Centro de Investigaciones Históricas (University of Puerto Rico-Rı́o Piedras), the Instituto de Cultural Puertorriqueña, Departamento de Recursos Naturales y Ambientales de Puerto Rico, the British Academy and the Centro de Estudios Avanzados de Puerto Rico y El Caribe. We are also indebted to Herb Allen III, Monica de la Torre, Delise Torres, Osvaldo de Jesús, Victor Serrano, Alex Palermo, Angel Vega, Paola Schiappacasse, Kate Jarvis, Tiana Garcı́a, Daniel Shelley, Rolf Vieten, Lucy Wrapson, David Redhouse, Tom Higham, Jose Rivera, Walter Cardona Bonet, Ovidio Dávila Dávila and Miguel Bonet for their contributions to this research. 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Received: 19 August 2015; Accepted: 17 November 2015; Revised: 24 November 2015 C© Antiquity Publications Ltd, 2016 1071 Introduction Isla de Mona Indigenous Amona European encounter on Mona Caves of Mona Cave 18 Indigenous mark-making Historic mark-making Archival research Discussion-‘The Mona Chronicle’ Corollary Acknowledgements References References work_3xdpzc3dwjhvta36ficxhu5rny ---- 329 Sa m m e lb e Sp r e c h u n g e n /e SS a y r e v ie w S n. T. m. 17 (2009) 329–338 0036-6978/09/030329–10 DOi 10.1007/ 00048-009-0346-1 © 2009 birkhäuSer verlag, baSel Naturgeschichte und wissenschaftliche Revolution Staffan Müller-Wille Barrera-Osorio, Antonio, 2006. Experiencing Nature. The Spanish American Empire and the Early Scientific Revolution. Austin: Uni- versity of Texas Press, geb. 211 S., 45 $, ISBN-13: 978-0292709812. Cook, Harold J., 2007. Matters of Exchange. Commerce, Medici- ne, and Science in the Dutch Golden Age. New Haven/London: Yale University Press, geb. xiv+562 S., 25 £, ISBN-13: 978-0300117967. Cooper, Alix, 2007. Inventing the Indigenous. Local Knowledge and Natural History in Early Modern Europe. Cambridge: Cam- bridge University Press, geb. xiv+218 S., 47 £, ISBN-13: 978-0521870870. Ogilvie, Brian, 2006. The Science of Describing. Natural History in Renaissance Europe. Chicago/London: The University of Chicago Press, geb. 431 S., 45 $, ISBN-13: 978-0226620886. Die wissenschaftliche Revolution ist gehörig in Verruf geraten. In ihrer Ein- leitung zu dem Band zur Wissenschaft in der frühen Neuzeit der Cambridge History of Science konstatieren Lorraine Daston und Katherine Park, dass „traditionelle Behauptungen über die wissenschaftliche Revolution als Ur- sprung der modernen Welt (oder auch nur moderner Wissenschaft) nicht mehr überzeugen“ (Park/Daston 2006: 13; meine Übersetzung, ebenso die folgenden). Allerdings lassen die Autorinnen ausdrücklich offen, ob die wis- senschaftliche Revolution sich nach allem nicht doch auch anders begreifen ließe: weniger vielleicht als epochemachendes Ereignis, in Analogie zur fran- s STaffan müller-wille 330 zösischen Revolution, denn als eine epochale Umwälzung in der Bewertung und Organisation gesellschaftlichen Wissens, in Analogie also zur industriel- len Revolution, die ihr auf lange Sicht immerhin auf dem Fuße folgte. In die- sem Sinne lässt sich für die Neuzeit in der Tat ein wichtiger Trend feststellen, der ein Wissensfeld betrifft, das von der Wissenschaftsgeschichte lange ver- nachlässigt worden ist, die Naturgeschichte nämlich. Sie erfuhr, zunächst im Rahmen der materia medica, eine zunehmende Aufwertung als Garant einer durch Erfahrung und eigene Anschauung statt durch Schlussfolgerung und Autorität geleiteten Wissenschaft. Der prominenteste Fürsprecher dieser Aufwertung war der englische Rechtsgelehrte und Staatsmann Francis Bacon (1561–1621). Allerdings ließ er sie nicht für Naturgeschichten in jeder beliebigen Form gelten. Eine bloß „narrative“ Naturgeschichte, wie er sie nannte, verglich Bacon mit einem „Königreich, das sich in seinen Angelegenheiten und Geschäften von Stra- ßengerüchten, und nicht von Briefen und Berichten vertrauenswürdiger Kuriere und Botschafter leiten läßt“ (1. Bd., S. 4, 94). Eine „induktive“ Na- turgeschichte hing von Infrastrukturen der Informationsverarbeitung ab, Formen des „intelligencing“, wie es zeitgenössisch hieß, die vom Arrange- ment von Schrift- und Bildelementen auf dem Papier über den Aufbau von Korrespondenznetzwerken bis zur Einrichtung von zentralen Institutionen wie Bibliotheken, botanischen Gärten und Laboratorien reichten. Ein sol- ches Unternehmen – ein wahrhaft „königliches Werk“, wie Bacon meinte – konnte nur kollektiv und über lange Zeiträume realisiert werden, wobei keineswegs von vorneherein feststand, welche Techniken und Strategien er- folgreich sein würden. Die Geschichte der Naturgeschichte spielte sich in der Entwicklung von Medien der Informationsverarbeitung sowie im Auf- und Ausbau von Netzwerken eines verlässlichen Informationsaustauschs ab (vgl. Dauser/Hächler/Kempe/Mauelshagen/Stuber 2008), und in beiden Hinsichten durchlebte die frühe Neuzeit mit der Erfindung des Buchdrucks und der Globalisierung des Handels enorme Umwälzungen. Nachdem seit Mitte der 1990er Jahre bereits mehrere Sammelbände er- schienen sind, in denen auf diese Zusammenhänge aufmerksam gemacht wurde (Jardine/Secord/Spary 1996, Smith/Findlen 2001, Schiebinger/Swan 2005), liegen aus den vergangenen drei Jahren nun auch eine Reihe von Mo- nographien vor. Sie werfen neues Licht auf die verwirrende, sich oft in aben- teuerliche Biographien und minutiöse Einzelheiten verlaufende Geschichte der frühneuzeitlichen Naturgeschichte und dürften auf lange Sicht zu einer endgültigen Dezentrierung des bisherigen Bildes von der wissenschaftlichen Revolution führen. So wendet sich Antonio Barrera-Osorio einer Institution zu, die in der Wissenschaftsgeschichte bislang überhaupt nicht oder allen- falls als randständig wahrgenommen wurde: die Casa de la Contratación (Haus des Handels), die 1503 von der spanischen Krone in Sevilla eingerich- tet wurde, um die Handelsbeziehungen mit der Neuen Welt zu organisie- naTurgeSchichTe unD wiSSenSchafTliche revOluTiOn 331 Sa m m e lb e Sp r e c h u n g e n /e SS a y r e v ie w S ren (S. 14). Eine ganz ähnliche Institution, mit dem bezeichnenden Namen Casa da Índia e Mina, war bereits fünf Jahre zuvor – also bloß sechs Jahre nach Christopher Columbus’ Landung in der Karibik – in Lissabon gegrün- det worden und diente als Vorbild (S. 32–35). 1524 wurde der Casa de la Contratación noch der Consejo de Indias zur Seite gestellt, der sich auf juris- tische und administrative Aspekte in Bezug auf die neuen Besitzungen der spanischen Krone in Übersee konzentrierte. Ursprünglich bestand die zentrale Aufgabe der Casa de la Contratación in der Entsendung von Handelsflotten und dem Eintreiben von Steuern. Bei- de Aufgaben erforderten verlässliches Wissen über Seerouten, Geographie, natürliche Ressourcen und Einwohnerschaft in den neuen Gebieten. Einer der Schwerpunkte der Tätigkeit der Casa de la Contratación wurde, neben der Erstellung von Seekarten, daher schon bald das geordnete Sammeln, Prüfen und Weiterreichen solchen Wissens. Barrera-Osorios übersichtlich gegliedertes und knapp gehaltenes Buch liefert ein Panorama der dabei zum Einsatz gekommenen empirischen Verfahren. Zwei Verfahren wirken aus heutiger Sicht besonders progressiv, da sie das heutige Lizenz- und Patent- wesen vorwegnehmen (S. 60). Barrera-Osorio diskutiert diese Verfahren aus- führlich am Beispiel von Antonio de Villasante, der 1528 von Santo Domingo nach Spanien reiste, um vom Consejo de Indias ein Monopol über den Han- del mit einer Reihe pflanzlicher Drogen zu erwerben. Darunter ein „Balsam“, der aus einem in Santo Domingo wachsenden Baum gewonnen wurde und über dessen medizinische Wirksamkeit Villasante von seiner einheimischen Frau erfahren hatte. Der Consejo war bereit, Villasante das Monopol zuzu- gestehen, allerdings nur im Tausch gegen einen „langen und sehr vollstän- digen Bericht über den Baum, […] wie seine Form beschaffen ist, wo er zu finden ist, und welches Verfahren verwendet wird, um [den Balsam] daraus zu gewinnen“ (S. 16). „Balsam“ war eine auch in Europa produzierte, jedoch ausgesprochen rare Droge. Und um die Identität von Villasantes „Balsam“ entspann sich schon bald ein Streit. Ihn suchte die Krone zu schlichten, in- dem sie Ärzten und Hospitälern anordnete, den neuen „Balsam“ Prüfungen (esperiencias) zu unterziehen (S. 15–23). Ähnliche Lizenz- und Testverfah- ren kamen bei der Validierung von Artefakten und technischen Verfahren zum Einsatz, die in der Neuen Welt entwickelt wurden (S. 60–65). Auch die Zuteilung von indigenen Arbeitskräften an die spanischen Kolonisten war an die Auflage gebunden, Beschreibungen und Zeichnungen des bearbei- teten Landes, Erhebungen zur Bevölkerungsstruktur und Angaben zu be- steuerbaren Gütern zu liefern (S. 82). Die Casa de la Contratación besaß aber auch ihre eigenen Experten und bildete solche auch aus, sogenannte „Piloten“, die die Navigation auf den nach Übersee entsandten Schiffen übernahmen. 1508 wurde Amerigo Vespucci zum obersten „Piloten“ (piloto mayor) ernannt und mit der Aufga- be betraut, Seekarten zu erstellen, künftige Piloten in Navigation auszubilden STaffan müller-wille 332 und Prüfungen abzunehmen. 1523 kam ein „Kosmograph“ hinzu, der für die Entwicklung und Herstellung von Navigationsinstrumenten zuständig war, und 1552 ein weiterer „Kosmograph“, der nun allein für die Ausbildung von „Piloten“ zuständig war (S. 36–38). Ausbildung und abschließende Prüfung verbanden Theorie und Praxis, und die Casa wurde zu einer Institution, in deren Kontext „die Produktion von Wissen dazu diente, menschliche und materielle Ressourcen in Agenten und Instrumente imperialer Herrschaft zu verwandeln“ (S. 48). Francisco Hernandez’ Expedition nach Mexiko in den Jahren 1571 bis 1577 sowie die Relaciones geográficas de Indias, die in den 1570er Jahren nach Aussenden eines gedruckten, 37 Kapitel umfassenden Fragebogens an Gouverneure und Bürgermeister in der Neuen Welt vom Consejo de Indias zusammengetragen wurden, bildeten den Höhepunkt die- ser Produktion (S. 94–98). Ihren Niederschlag fand sie, wie Barrera-Osorio im letzten Kapitel seines Buches nachweist, in den gedruckten Werken von Gonzalo Fernández de Oviedo (Historia natural y general de las Indias, 1535 und 1557) und José de Acosta (Historia natural y moral de las Indias, 1590), für die bereits ein ausgeprägtes Bewusstsein für die kollektive Natur verläss- lichen Wissens charakteristisch ist (S. 118). Die Casa de la Contratación blieb vorerst eine einzigartige, aber durchaus nicht unbeachtete Institution im frühneuzeitlichen Europa, wie Barrera be- tont (S. 132). Angesichts der Konkurrenz, in der sich die europäischen Groß- mächte um die Dominanz über Welthandelsrouten und Niederlassungen in Übersee befanden, dürfte dies kaum überraschen. Eine ähnlich zentrale, straff bürokratisch organisierte und staatlich gelenkte Institution schuf al- lerdings keine von ihnen. Das Bild, welches das übrige Europa in Hinsicht auf empirische Praktiken bot, ist wesentlich diffuser, auch wenn es ähnliche Elemente wie in Spanien aufweist. Harold J. Cook geht diesen Elementen in aller Ausführlichkeit für die Niederlande in ihrem sogenannten „Goldenen Zeitalter“ nach, also in den Jahren, die zwischen der Unabhängigkeit der sie- ben nördlichen Provinzen von den Habsburgern in den 1580er Jahren und dem Ende des 17. Jahrhunderts liegen. Cook spannt einen weiteren, kultur- geschichtlichen Bogen als Barrera-Osorio, indem er im Anschluss an Georg Simmel die Frage aufwirft, welches kreative Potential die „Informationsöko- nomie“, das heißt der Austausch von Worten, Dingen und Personen, der die Niederlande mit dem Rest der Welt verband, freisetzte (S. 42–49). Cooks Antwort auf diese Frage fällt unmissverständlich aus: Nichts weniger als „die sogenannte wissenschaftliche Revolution“, hält er am Ende des zweiten Ka- pitels fest, resultierte aus den globalen Bewegungen von Waren, Nachrich- ten und Personen und den damit verbundenen „zahllosen Bemühungen […] sicherzustellen, ob Informationen zutreffend und kommensurabel waren“. „Objektivität“, so Cook weiter, „hatte die Macht, Appetit zu wecken, ja so- gar Wahrnehmungen, Begriffe und moralische Bedenken zu verändern. Sie schwebte nicht über der Welt, sondern war tief mit ihr verstrickt.“ (S. 81) naTurgeSchichTe unD wiSSenSchafTliche revOluTiOn 333 Sa m m e lb e Sp r e c h u n g e n /e SS a y r e v ie w S Cook belegt dies in einer Reihe von thematisch und chronologisch ge- schlossenen, relativ locker aneinander gereihten Kapiteln, die eine große Bandbreite von religions-, philosophie-, wissenschafts- und technikhisto- rischen Themen mit einem gemeinsamen Fluchtpunkt in der Medizinge- schichte abdecken. So legt er in Kapitel 3 anhand der Biographie des Bota- nikers Carolus Clusius dar, dass der niederländische Humanismus nicht so sehr an die eine oder andere Konfession gebunden war, sondern vielmehr an die Fähigkeit, sich der Herrschaft religiöser Dogmen zu entziehen (S. 84) und sich als „Mann von Welt“ relativ frei in unterschiedlichsten Kontexten zu bewegen (S. 131). In Kapitel sechs widmet sich Cook der empiristischen Wende im Spätwerk René Descartes’ – „einem der bedeutendsten nieder- ländischen Philosophen seiner Zeit“, wie er süffisant bemerkt (S. 227) –, und im zehnten Kapitel behandelt er Hermann Boerhaaves Iatromechanismus im Wesentlichen als deskriptives statt theoretisches Unternehmen. In den übrigen Kapiteln hält sich Cook enger an das eigentliche Thema von Mat- ters of Exchange, die Konsonanz zwischen der „neuen Philosophie“ und den „Werten, die im Handel eingebettet waren“ (S. 410), indem er auf die hart umkämpften „medizinischen Märkte“ in den städtischen Zentren der Nie- derlande, insbesondere aber auf deren komplexe Translationsbeziehungen in den ostasiatischen Raum eingeht. Dabei kamen ganz ähnliche empirische Praktiken ins Spiel, wie sie Barrera-Osario für die Casa de la Contratación beschreibt, wenn auch in einem wesentlich diffuseren und konfliktreicheren Feld disparater Institutionen und Kontaktzonen. Besonders faszinierende Analysen solcher Praktiken bietet Cook mit sei- nen Fallstudien zu Jakobus Bontius, der 1627 bis 1631 im Auftrag der Ver- einigten Ostindischen Compagnie (VOC) das Medizinalwesen in Batavia (heute Jakarta) überwachte und dort nosographische, diätetische und na- turhistorische Manuskripte zusammenstellte, die eine Vielzahl von lokalen, schriftlichen wie mündlichen Quellen vereinten (S. 191–209); zu Jan Swam- merdam, dessen anatomische, mikroskopische und chemische Studien von dem Versuch angestoßen wurden, ein von Louis de Bils in den späten 1650er Jahren entwickeltes, aber noch erfolgreich geheim gehaltenes Verfahren zur Konservierung anatomischer Präparate offen zu legen und weiter zu entwi- ckeln (S. 276–292); zu Hendrik Adriaan van Reede tot Drakenstein, Kom- mandant einer Reihe von holländischen Handelsniederlassungen entlang der Südwestküste des indischen Subkontinents, der Mitte der 1670er Jahre ein regelrechtes Komitee – zusammengesetzt aus europäischen und indigenen Experten, Klerikern, Kaufleuten, Apothekern, Ärzten und Brahmanen – zu- sammenstellte, um die lokale Flora systematisch zu explorieren (S. 310-317); sowie schließlich zu Willem ten Rhijne, der 1674 auf ausdrücklichen Wunsch des japanischen Kaisers hin von der VOC nach Deshima entsandt wurde, um japanische Ärzte und Gelehrte über europäische Heilkunde zu unterrichten, und der im Gegenzug nach seiner Rückkehr aus Japan europäische Gelehr- STaffan müller-wille 334 te mit den diagnostischen (Pulsnehmen) und therapeutischen Techniken (Akupunktur, Moxibustion) der chinesischen Medizin vertraut machte (S. 349–377). Was in diesen Fallstudien deutlich wird, ist nicht nur die Inten- sität – und gelegentlich menschenverachtende Brutalität –, mit der um die Vorherrschaft im Handel mit „Kuriositäten“ und Exotika gekämpft wurde, sondern auch die daraus resultierende Tendenz, den Diskurs auf „Tatsachen“ (matters of fact) zu reduzieren. „Viele Dinge gingen von einer Sprache zur anderen über“, schreibt Cook zusammenfassend, „aber sie neigten dazu, zur Welt der Objektivität zu gehören: schlichte Hauptworte, Adjektive und Verben, die das bezeichnen, was die Sinne uns berichten.“ (S. 377) Wenn es soweit den Anschein haben könnte, als sei es insbesondere und ausschließlich der Fernhandel gewesen, der diese „Welt der Objektivität“ ins Leben rief, so belehrt uns Alix Cooper eines Besseren. Sie beginnt ihr Buch mit einer vielleicht überraschenden, sprachgeschichtlichen Tatsache, näm- lich dass Ausdrücke wie „eingeboren“ oder „indigen“ im Europa der frühen Neuzeit nicht etwa auf außereuropäisches Bezug nahmen, sondern vielmehr einem „nach innen“ gerichteten Blick entsprangen. In einer Art Gegenbe- wegung zu den von Barrera-Osorio und Cook beschriebenen Handels- und Verkehrsströmen wandten sich Mediziner und Botaniker der Erforschung naheliegenderer, heimischer Ressourcen zu, insbesondere in Regionen wie dem deutschsprachigen Raum, die aufgrund ihrer kontinentalen Lage nur aus zweiter Hand an diesen Strömen partizipieren konnten. Ideologisch wurde diese Gegenbewegung von Überzeugungen getragen, die eine enge Kopplung von geographischem Raum, spezifischen Krankheiten und einhei- mischen Heilmitteln behaupteten, polemisch die Nützlichkeit importierter Drogen bestritten und Autarkie als wirtschaftspolitisch erstrebenswertes Ziel bezeichneten. Insbesondere Paracelsisten machten sich in dieser Hin- sicht lautstark bemerkbar (S. 29–31), ähnliche Ansichten finden sich aber auch bei Humanisten wie Hieronymus Bock, Symphorien Champier, Robert Burton und Jan van Beverwyck (S. 35–45). Coopers groteske Überzeichnung Carl von Linnés als Botaniker, der am Ende der von ihr betrachteten Periode „die Beiträge zur lokalen Naturgeschichte stark entwertete“ (S. 167), deutet darauf hin, dass es sich bei der Akzentuierung des Gegensatzes von lokalem und globalem Naturwissen oft nur um eine rhetorische Taktik gehandelt haben dürfte, denn gerade Linné ging, wie Cooper eingesteht (S. 170), von einer Vereinbarkeit der beiden Pole aus. Dies sollte aber nicht davon ablen- ken, dass sich parallel zur Erforschung außereuropäischer Floren und Fau- nen auch die Perspektive auf europäische Naturräume in der frühen Neuzeit radikal verschob. Cooper zeigt dies, indem sie mit großer Aufmerksamkeit für buchhis- torische Details die Entstehungsgeschichte von neuartigen Genres in der naturhistorischen Literatur nachzeichnet. Da sind zunächst die im frühen 17. Jahrhundert vor allem im deutschsprachigen Raum einsetzenden Pu- naTurgeSchichTe unD wiSSenSchafTliche revOluTiOn 335 Sa m m e lb e Sp r e c h u n g e n /e SS a y r e v ie w S blikationen von lokalen Floren zu nennen, die sich auf die Aufzählung der Pflanzenarten beschränkten, die in den Gärten und im näheren Umkreis ei- ner Universitätsstadt anzutreffen waren (S. 55). Von handlichem und schon bald standardisiertem, auf Nennung, kurze Diagnose, Standort und gegebe- nenfalls Nutzen reduziertem Format, begleiteten diese Lokalfloren als regel- rechte „Taschenbücher“ (S. 73) Studenten und Lehrer der materia medica auf ihren Exkursionen, wie erhalten gebliebene, durchschossene und reich annotierte Exemplare beweisen (S. 75). Bereits 1727 war beispielsweise die Flora um Altdorf in einem halben Dutzend solcher Kataloge dokumentiert, während dieses Format erst gegen Ende des 17. Jahrhunderts auch in exo- tische Regionen übertragen wurde, etwa mit der Flora Jamaicensis, die Hans Sloane 1696 veröffentlichte (S. 71f.). Neben dieser Transposition des Modells der Lokalflora in koloniale Kon- texte beobachtet Cooper aber auch seine Ausweitung am Ende des 17. Jahr- hunderts auf regionale und territoriale Naturgeschichten innerhalb Europas. Erstere untersucht sie am Beispiel von Veröffentlichungen, die im Schnitt- feld von Kameralismus und Naturtheologie Bestandsaufnahmen der Boden- schätze einer bestimmten Region lieferten, letztere vor allem im Werk des Schweizer Naturhistorikers Johann Jakob Scheuchzer. Naturgemäß waren diese Unternehmen in weit größerem Maße auf den Austausch zwischen Sammlern, Korrespondenz, umfangreiche bibliographische Recherchen und systematische Umfragen angewiesen. Wie wenig von vorneherein feststand, welche Form gerade letztere nehmen sollten, zeigt sich am Beispiel Hen- ry Oldenbourgs, der seinen Korrespondenten im Gegensatz zu Scheuchzer Auskünfte abverlangte, die zwar sehr spezifische Gegenstände betrafen, aber gleich für ganze Territorien abgegeben werden sollten (S. 122). Scheuchzer dagegen zeigte bei seinen Umfragen, vor allem aufgrund seiner bibliogra- phischen Studien, sehr viel mehr Sensibilität für die „Geopolitik der Wis- senschaft“ (S. 163). Das anscheinend „lokale“ Wissen, das sich in den von Cooper behandelten Werken niederschlug, war in Wahrheit „lokalisiertes“ Wissen (S. 86) – ein Wissen, welches zwar aus lokalen Quellen geschöpft wurde, aber doch in einem translokalen Netz von Literaturverweisen und Austauschbeziehungen eindeutig „verortet“ wurde. Diesen Gesichtspunkt macht sich Brian Ogilvie zu eigen. Seiner Auffas- sung nach nahm die Naturgeschichte bereits im Laufe der Renaissance die Züge einer „distinkten Disziplin“ (S. 2) an, nachdem sie zuvor allenfalls als Hilfswissenschaft von Medizin und Naturphilosophie gegolten hatte. Dabei macht er aus seiner Ablehnung von Interpretationen, die die frühmoderne Naturgeschichte in den Kontext von Patronage und „protokapitalistischen“ Tauschsystemen stellen, keinen Hehl (S. 13f.). Man kann ihm in diesem Punkt vielleicht vorwerfen, symbolischen mit kommerziellem Tausch zu verwech- seln – Carolus Clusius’ offenbarer Verwicklung in den Tulpenhandel gegen Ende des 16. Jahrhunderts begegnet er beispielsweise mit dem Hinweis, dass STaffan müller-wille 336 „Geld keinen Platz im Tausch [zwischen Botanikern] hatte“ (S. 78). Ogilvies Frage nach der spezifischen „kulturellen Form“ der frühmodernen Naturge- schichte bleibt für ein Verständnis der wissenschaftlichen Revolution jedoch relevant, da das, was dieser Form Identität gab, gerade die „Auseinanderset- zung um Methoden der Kommunikation und Reproduktion von Naturer- fahrung“ war (S. 15). Seine internalistische Perspektive fokussiert den Blick auf Probleme der Beschreibung, Kollation und Translation, die sich auch außerhalb der Disziplin Naturgeschichte stellten, aber innerhalb derselben geradezu zum identitätsstiftenden, epistemischen Objekt einer Wissenschaft wurden (S. 7f.). Ogilvie gliedert seine Darstellung nach vier Generationen, beginnend mit den italienischen Ärzten und Humanisten, die sich mit Ausgaben antiker Texte zur Botanik beschäftigten (1490 bis 1530), gefolgt von den meist aus Nordeuropa stammenden Verfassern früher Kräuterbücher (1530–1560), einer weiteren Generation, die sich in die aufblühende Sammlungskultur einschrieb (1560–1590), und schließlich einer vierten Generation, die sich angesichts der zu Tage tretenden Vielfalt von Naturobjekten mehr und mehr Fragen der Nomenklatur und Taxonomie zuwandte (1590–1620). Allerdings gibt er dieser relativ konventionellen Gliederung eine entscheidende Wen- dung, indem er jede dieser Generationen mit der kritischen Fortschreibung, der Korrektur und Ergänzung der Werke der vorangehenden Generation beschäftigt sieht. Für die erste Generation hatte noch die Identifikation der von Dioscurides und Plinius erwähnten Pflanzen im Vordergrund gestan- den, aber bereits 1492 trat Niccoló Leoniceno mit einem Buch über die zahl- reichen „Irrtümer“, die er vor allem Plinus unterstellen zu können glaubte, eine Debatte über die Vertrauenswürdigkeit antiker Quellen los (S. 126–131). Und die zweite Generation, die überwiegend an den oberitalienischen Uni- versitäten studiert hatte und das dort erworbene Wissen nun an nördlicher gelegene Universitäten trug, bezog ihren Antrieb vor allem aus der Tatsache, dass viele mitteleuropäische Pflanzenarten ihren Lehrern unbekannt geblie- ben waren (S. 137). Wie bei Barrera-Osorio, Cook und Cooper rücken so auch für Ogilvie die geographische und kollektive Dimension der frühneuzeitlichen Naturge- schichte in den Blickpunkt sowie die Techniken, die zur Überbrückung von räumlichen und zeitlichen Distanzen entwickelt wurden (S. 52–63). Seine Geographie bleibt allerdings auf die „Gelehrtenrepublik“ (republic of letters) Europas beschränkt, die sich im offenen Gegensatz zur höfischen und städ- tischen Kultur definierte (S. 58, 85). Spanische und portugiesische Gelehrte bleiben damit außen vor (S. 55), und Clusius erscheint mit seinen Reisen nach Wien und Spanien als ein „Odysseus des Hinterlands“ (S. 143). Der Vorteil dieser Beschränkung liegt darin, dass sich Ogilvie mit großer Ziel- genauigkeit an die Untersuchung der empirischen Verfahren machen kann, die Botaniker des 17. Jahrhunderts im engen Austausche miteinander entwi- naTurgeSchichTe unD wiSSenSchafTliche revOluTiOn 337 Sa m m e lb e Sp r e c h u n g e n /e SS a y r e v ie w S ckelten. Da ist an vorderster Stelle das Herbarium zu nennen, das als Unter- richtsmittel bereits Mitte des 16. Jahrhunderts verwendet wurde und sich im Laufe des 17. Jahrhunderts zu einem regelrechten Repositorium botanischen Wissens entwickelte, indem es mit Pflanzenzeichnungen integriert und als Projektionsfläche für laufende Annotationen verwendet wurde (S. 165–174). Daneben experimentierten Naturhistoriker mit einer Vielfalt von Aufzeich- nungs- und Exzerptverfahren, um Gelesenes und brieflich Mitgeteiltes nicht nur aufzubewahren, sondern auch neu zu arrangieren (S. 174–182). Aus solchen literarischen Techniken gingen im Druck Beschreibungen und Abbildungen hervor, die sich zum einen eng und mit standardisierter Terminologie und Gliederung an der Morphologie des Objekts orientierten – Ogilvie spricht von „stellvertretenden“ (vicarious) Beschreibungen, in- sofern sie den Leser glauben lassen, das Objekt selbst vor Augen zu haben (S. 183) –, zum anderen aber aus der Kollation einer Vielzahl von eigenen Beobachtungen und Beobachtungen anderer hervorgingen. Die Spannung zwischen diesen beiden Polen thematisiert Ogilvie am Ende seines Buches, wenn er die Verfahren diskutiert, die Konrad Gessner, Ulysse Aldrovandi und Carolus Clusius verwendeten, um durch Unterscheidung von abhängigen und unabhängigen Quellen die Vertrauenswürdigkeit von naturhistorischen Berichten zu überprüfen. Ironischerweise zeigen sich in diesen Fallstudien nicht nur die Grenzen der frühmodernen Naturgeschichte (S. 236), sondern auch die von Ogilvies eigenem Ansatz – soweit es die Tierwelt des Nordens anging, insbesondere das Walross, setzte Conrad Gessner offenbar viel Ver- trauen in den Portugiesen Damião da Goes, der sich im 16. Jahrhundert im- merhin selbst in Skandinavien aufgehalten hatte (S. 237); und das letzte Wort in der Frage, ob Paradiesvögel Beine haben oder nicht, behielten für Clusius Antonio Pigafetta, der Ferdinand Magellan auf dessen erster Weltumseglung begleitet hatte (1519–1522), und die Seeleute, die Bälge von Paradiesvögeln nach Europa einführten (S. 251). Die gelehrte Naturgeschichte scheint also trotz allem durchlässiger für die zahllosen, globalen Bewegungen von Personen und Dingen gewesen zu sein, die vor allem Cook so lebendig beschreibt und es spricht vieles dafür, dass die disziplinäre Eigendynamik, die sie in der frühen Neuzeit gewann, nur vor diesem bewegten Hintergrund zu verstehen ist. Paula Findlen be- hauptet, dass die massive Aufwertung, welche die Erfahrung aus eigener Anschauung zu Beginn des 16. Jahrhunderts erfuhr, paradoxerweise darauf zurückzuführen ist, dass mehr und genauer gelesen wurde (Findlen 2006: 442). Sowohl Barrera-Osorio (S. 8, 11) als auch Cook (S. 83f.) wenden sich ausdrücklich gegen die von Max Weber und Robert K. Merton aufgestellte These, dass Frühformen des Kapitalismus und der modernen Wissenschaft in ursächlichem Zusammenhang mit einer protestantischen Ethik standen. Trifft das von ihnen, aber auch von Cooper und Ogilvie gezeichnete Bild zu – und zieht man darüber hinaus noch neuere Arbeiten hinzu, welche die Be- STaffan müller-wille 338 deutung des atlantischen Raums für die Literatur- und Kunstgeschichte der alten wie neuen Welt betonen (Phaf-Rheinberger 2008) –, so steht die Wis- senschaftsgeschichte unverhofft vor dem Problem, dass die wissenschaft- liche Revolution nicht mehr auf einen plötzlichen Wandel in Weltbildern und Mentalitäten zurückzuführen ist, sondern als ein kumulativer und kol- lektiver Prozess verstanden werden muss, in dem Verfahren der Fixierung, Verarbeitung und Distribution von Erfahrungswissen ein zuvor nicht dage- wesenes, Grenzen und Traditionen überschreitendes Spiel von Überprüfung und Rückfrage, Ergänzung und Berichtigung ermöglichten. Literatur Dauser, Regina/Hächler, Stefan/Kempe, Michael/Mauelshagen, Franz/Stuber, Martin, Hg., 2008. Wissen im Netz. Botanik und Pflanzentransfer in europäischen Korrespondenznetzen des 18. Jahrhunderts. Berlin: Akademie Verlag (=Colloquia Augustana 24). Findlen, Paula, 2006. Natural History. In: Katharine Park und Lorraine Daston, Hg., Early Mo- dern Science. Cambridge: Cambridge University Press (=The Cambridge History of Science, 3), 435–468. Jardine, Nick/Secord, James A./Spary, Emma C., Hg., 1996. Cultures of Natural History. Cam- bridge: Cambridge University Press. Park, Katherine/Daston, Lorraine, 2006. Introduction: The Age of the New. In: Katharine Park und Lorraine Daston, Hg., Early Modern Science. Cambridge: Cambridge University Press (=The Cambridge History of Science, 3), 1–17. Phaf-Rheinberger, Ineke. 2008. The Air of Liberty. Narratives of the South Atlantic Past. Amster- dam: Rodopi. Smith, Pamela/Findlen, Paula, Hg., 2001. Merchants and Marvels: Commerce, Science, and Art in Early Modern Europe. London: Routledge. Schiebinger, Londa/Swan, Claudia, Hg., 2005. Colonial Botany. Science, Commerce, and Politics in the Early Modern World. Philadelphia: University of Pennsylvania Press. Staffan Müller-Wille ESRC Centre for Genomics in Society University of Exeter Byrne House, St Germans Road Exeter, Devon EX4 4PJ Großbritannien E-Mail: S.E.W.Mueller-Wille@exeter.ac.uk work_3yona5tboba47fgb6g65jjzhwu ---- 2) Onchocerciasis | Semantic Scholar Skip to search formSkip to main content> Semantic Scholar's Logo Search Sign InCreate Free Account You are currently offline. Some features of the site may not work correctly. DOI:10.2149/tmh.2015-S09 Corpus ID: 160386682) Onchocerciasis @article{Tada20152O, title={2) Onchocerciasis}, author={I. Tada}, journal={Tropical Medicine and Health}, year={2015}, volume={43}, pages={47 - 56} } I. Tada Published 2015 Medicine Tropical Medicine and Health Although onchocerciasis in cattle and horses in Japan had been noted in the veterinary field since the early 1950s, research on human onchocerciasis that is caused by Onchocerca volvulus was carried out only in the early 70s. It began when I did a brief study of skin test for onchocerciasis cases in Guatemala, Central America, in collaboration with Dr. H. Figueroa [1] using a Dirofilaria antigen [2]. Dr. Figueroa was an admirer of Dr. R. Robles, who discovered the presence and distribution of… Expand View on PubMed jstage.jst.go.jp Save to Library Create Alert Cite Launch Research Feed Share This Paper Topics from this paper Onchocerciasis Ivermectin di-(4-aminophenyl)ether Behavior Proprietary Name Intestinal Volvulus References SHOWING 1-10 OF 120 REFERENCES SORT BYRelevance Most Influenced Papers Recency Second case of zoonotic Onchocerca infection in a resident of Oita in Japan. H. Takaoka, O. Bain, +5 authors Y. Otsuka Biology, Medicine Parasite 1996 36 PDF View 1 excerpt, references background Save Alert Research Feed A biometric study ofOnchocerca volvulus microfilariae from Nigeria using the nuclear counting method T. Mimori, I. Tada, K. Shiwaku, G. O. Ufomadu, B. Nwoke Biology, Medicine Zeitschrift für Parasitenkunde 2004 3 View 1 excerpt, references background Save Alert Research Feed Endemic onchocerciasis on the Jarawa valley area of Plateau state, Nigeria. B. Nwoke, C. Onwuliri, K. Shiwaku, G. O. Ufomadu, I. Tada, H. Takahashi Medicine 1989 8 View 1 excerpt, references background Save Alert Research Feed SIMULIUM DAMNOSUM, NATURALLY INFECTED WITH ONCHOCERCA VOLVULUS IN SOUTH-WEST ETHIOPIA I. Tanaka, Y. Inoue, I. Tada, I. Iwamoto, T. Wonde Biology 1973 3 View 1 excerpt, references background Save Alert Research Feed Onchocerciasis in San Vicente Pacaya, Guatemala. I. Tada, Y. Aoki, +8 authors H. Takahashi Biology, Medicine The American journal of tropical medicine and hygiene 1979 18 PDF View 1 excerpt Save Alert Research Feed A sero-epidemiological study of onchocerciasis with the indirect hemagglutination test. T. Ikeda, Y. Aoki, I. Tada, M. Recinos, J. O. Ochoa, P. A. Molina Biology, Medicine The Journal of parasitology 1979 14 View 1 excerpt, references background Save Alert Research Feed Bovine and equine onchocerciasis in Guatemala, especially in San Vicente Pacaya. Y. Hashiguchi, I. Tada, J. O. Ochoa, M. Recinos, P. A. Molina Biology, Medicine The Journal of parasitology 1981 5 View 1 excerpt, references background Save Alert Research Feed Theoretical approach to the epidemiology of onchocerciasis in Guatemala. Y. Wada Biology, Medicine Japanese journal of medical science & biology 1982 28 View 1 excerpt, references methods Save Alert Research Feed A Human Case of Zoonotic Onchocerciasis in Japan H. Hashimoto, I. Murakami, +6 authors H. Yoshimura Biology, Medicine The Journal of dermatology 1990 26 View 1 excerpt, references background Save Alert Research Feed Specific serodiagnosis with adult Onchocerca volvulus antigen in an enzyme-linked immunosorbent assay. I. Tada, M. Korenaga, K. Shiwaku, E. O. Ogunba, G. O. Ufomadu, B. Nwoke Biology, Medicine The American journal of tropical medicine and hygiene 1987 10 View 1 excerpt, references background Save Alert Research Feed ... 1 2 3 4 5 ... Related Papers Abstract Topics 120 References Related Papers Stay Connected With Semantic Scholar Sign Up About Semantic Scholar Semantic Scholar is a free, AI-powered research tool for scientific literature, based at the Allen Institute for AI. 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The Columbian Exchange is widely appreciated by historians, social scientists and economists as a major turning point that had profound and lasting effects on the trajectory of human history and development. Presentation of the hypothesis: I propose that the Columbian Exchange should also be appreciated by biologists for its role in the creation of novel human genomes that have been shaped by rapid adaptive evolution. Specifically, I hypothesize that the process of human genome evolution stimulated by the Columbian Exchange was based in part on selective sweeps of introgressed haplotypes from ancestral populations, many of which possessed pre-evolved adaptive utility based on regional-specific fitness and health effects. Testing the hypothesis: Testing of this hypothesis will require comparative analysis of genome sequences from putative ancestral source populations, with genomes from modern admixed populations, in order to identify ancestry-specific introgressed haplotypes that exist at higher frequencies in admixed populations than can be expected by chance alone. Investigation of such ancestry-enriched genomic regions can be used to provide clues as to the functional roles of the genes therein and the selective forces that have acted to increase their frequency in the population. Implications of the hypothesis: Critical interrogation of this hypothesis could serve to underscore the important role of introgression as a source of adaptive alleles and as a driver of evolutionary change, and it would highlight the role of admixture in facilitating rapid human evolution. Reviewers: This article was reviewed by Frank Eisenhaber, Lakshminarayan Iyer and Igor B. Rogozin Keywords: Columbian exchange, Human evolution, Adaptive evolution, Natural selection, Selective sweep, Genetic admixture, Introgression, Haplotype, Allele Background The Columbian Exchange The historian Alfred Crosby coined the term “Colum- bian Exchange” to describe the extensive transfer of life between the Afro-Eurasian (Old World) and American (New World) hemispheres following Christopher Col- umbus’ voyage of 1492 [1]. The Columbian Exchange was a byproduct of subsequent European colonization and trade efforts in the Americas, and it entailed a bidir- ectional transfer of numerous species of plants, animals and microbes between the Old and New Worlds (Fig. 1a). This transfer also included human population groups, cultures and technologies, and as such it led to major demographic shifts in both hemispheres [2]. The introduction of calorically rich and nutritional New World crop species – potatoes, maize and cassava in particular – facilitated agricultural developments that allowed for sustained population growth in the Old World [3]. The demographic changes in the New World Correspondence: king.jordan@biology.gatech.edu 1School of Biology, Georgia Institute of Technology, 950 Atlantic Drive, Atlanta, GA 30332, USA 2PanAmerican Bioinformatics Institute, Cali, Valle del Cauca, Colombia Full list of author information is available at the end of the article © 2016 Jordan. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. Jordan Biology Direct (2016) 11:17 DOI 10.1186/s13062-016-0121-x http://crossmark.crossref.org/dialog/?doi=10.1186/s13062-016-0121-x&domain=pdf mailto:king.jordan@biology.gatech.edu http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/publicdomain/zero/1.0/ http://creativecommons.org/publicdomain/zero/1.0/ 60 50 40 30 20 10 EuropeanAfrican L o cu s -s p e ci fic a n ce st ry % A fr ic a n a n ce st ry Avg. -3 +3 el ell a evit p a d A )f( y c n e u q erf 1.0 0.8 0.6 0.4 0.2 0 Number of generations (g) 0 50 100 150 200 Rapid evolution 25g ~ f > 0.5 b c a Banana Sugar cane Cattle Horses Malaria Measles Smallpox Cacao Cassava Maize Potato Tomato Turkey Syphilis Fig. 1 Adaptive introgression via the Columbian Exchange. a Examples of plants, animals and microbes transferred between the Old and New Worlds during the Columbian Exchange. Human populations from Europe, Africa and the Americas were also brought together during this era. b The number of generations needed to fix an adaptive allele is modeled for a selection coefficient (s) of 0.01 and a dominance coefficient (h) of 1.0. The level of per-generation adaptive change in allele frequencies varies over four orders of magnitude and reaches its maximum at intermediate allele frequencies. c Ancestry-enrichment analysis for the adaptive introgression events. An example is shown for a single chromosome from a hypothetical admixed population with African (avg = 30 %) and European (avg = 70 %) ancestry. Locus-specific ancestry is assigned for all chromosomes in the admixed population, and regions with anomalously high (or low) ancestral origins are identified for further investigation Jordan Biology Direct (2016) 11:17 Page 2 of 8 during this era were even more drastic. The Columbian Exchange brought together previously isolated popula- tions from Europe, Africa and the Americas in the New World colonies over a relatively short period of time. More than 50 million Europeans migrated to the Ameri- cas through the nineteenth century [4], and the African slave trade resulted in forced migration of 12 million Af- ricans to the New World over a period of ~450 years [5]. The indigenous population of the New World, on the other hand, was reduced by up to 95 % within 100– 150 years after Columbus maiden voyage, a loss of an es- timated 10–100 million lives [6]; this was largely a result of the introduction of Old World infectious diseases, such as small pox, measles and malaria, to which native populations had little or no resistance. One can expect that such a profound human demographic transform- ation would occasion substantial evolutionary change at the genomic level. From a population genomic perspective, the Colum- bian Exchange can be considered to have facilitated gen- etic admixture among three human population groups – African, European and Native American – that had pre- viously evolved separately for many thousands of years [7–10]. During the time that these populations were iso- lated, they accumulated numerous genetic (allele fre- quency) differences. Many of these differences were likely to be neutral changes with no appreciable effects on fitness, whereas others were the result of adaptations to local selection pressures [11, 12]. In either case, the accumulation of such population-characteristic genetic differences resulted in the presence of distinct haplo- types (i.e., combinations of linked alleles) that are spe- cific to individual populations; the process of admixture during the Columbian Exchange then led to the repeated introgression of these population-specific haplotypes onto distinct genomic backgrounds. In other words, population mixing during the Columbian Exchange gen- erated novel human genome sequences with combina- tions of haplotypes that had never previously co-existed in the same genome. I am interested in exploring the implications of the rapid creation of such novel, admixed American genome sequences for adaptive human evolu- tion, fitness and health. Adaptive introgression and rapid human evolution As mutation is the ultimate source of novel adaptive al- leles, it can be considered to be a critical rate limiting step for adaptive evolution. Human germline mutation rates are low [13], and accordingly adaptive evolution in human populations is generally considered to be a slow process that takes place over many thousands of years [12, 14, 15]. However, introgression can also be an im- portant source of novel alleles for human adaptation [16]. Indeed, a number of recent studies have provided evidence for adaptive evolution of haplotypes that were introgressed from archaic human genomes (Neandertal and/or Denisovan) into modern human genomes [17– 20]. Introgression has the potential to speed adaptive evolution by introducing novel alleles at a relatively rapid rate compared to de novo mutation. If genetic admixture between previously isolated popu- lations is extensive, it can provide introgressed haplo- types at intermediate to high frequencies to the resulting admixed population. Introgression could thereby in- crease the rate of adaptive evolution by elevating the fre- quency of potentially beneficial alleles available in the population. In this sense, introgression of adaptive alleles can be considered to provide an opportunity for so- called ‘soft’ selective sweeps, which are defined as caus- ing rapid molecular evolution via the simultaneous in- crease in frequency of multiple adaptive alleles in the population [21]. Soft selective sweeps can occur under several distinct evolutionary scenarios, including the case where multiple adaptive alleles pre-exist in the population as standing genetic variation [22]. Introgres- sion on the scale seen for the three-way population mix- ing that characterized the Columbian Exchange [7–10] could have provided multiple adaptive alleles as standing genetic variation at intermediate to high population frequencies. Presentation of the hypothesis I hypothesize that genetic admixture and introgression among the human population groups brought together via the Columbian Exchange provided the opportunity for rapid adaptive evolution based on the existence of numerous pre-adapted haplotypes. In other words, intro- gression during the Columbian Exchange provided ex- tensive standing genetic variation to New World populations, much of it with potential adaptive signifi- cance, which could have provided the raw material for numerous (partial) selective sweeps. The three ancestral human population groups – African, European and Native American – that were brought to- gether over the last 500 years during the course of the Co- lumbian Exchange began to diverge ~60–100,000 years ago (ya) as modern humans emerged from Africa and spread around the world [23]. Europe was populated by anatomically modern humans ~40–45,000 ya [24, 25], and humans reached the Americas ~15,000 ya via several waves of migration across the Bering Strait [26, 27]. As these three population groups were isolated during the course of human evolution, they diverged genetically, ac- cumulating numerous allele frequency differences. A number of these allele frequency differences were likely to be adaptive substitutions with regional-specific utility for health and fitness [11, 12, 15]. These pre-evolved adaptive alleles, and the ancestry-specific haplotypes on which they Jordan Biology Direct (2016) 11:17 Page 3 of 8 reside, could have been selected in the admixed American population based on their utility in the New World envir- onment. The process of selection in this case would be based on differential retainment of ancestry-specific hap- lotypes that provide relatively higher fitness in the admixed population. The New World environment that served as the se- lective crucible for the introgressed haplotypes would have consisted of both the external physical environ- ment as well as the internal microbial environment, which was shaped by the mixture of microbes endemic to the ancestral source populations. The novel microbial environment in particular is likely to have exerted strong selective pressure on New World populations, based on the need to respond to the challenge of infectious patho- gens, suggesting that immune system genes would be particularly prone to introgression-accelerated adaptive evolution [28–30]. It should be noted that the ~500 years that have elapsed during the era of the Columbian Exchange is an extremely short amount of time with respect to human evolution; indeed, it would correspond to a mere 20–25 generations assuming a generation time of 20–25 years. Irrespective of the role of introgression in providing standing adaptive genetic variation to an admixed popu- lation, this would not likely be enough time to allow for the complete fixation of adaptive alleles. Thus, the kind of introgression-facilitated adaptive evolution proposed here would amount to partial (or ongoing) selective sweeps [31]. Nevertheless, substantial levels of allele fre- quency change can in fact occur over this time scale. A standard model for the rate of fixation of an adaptive al- lele illustrates how selective increase in allele frequency proceeds successively through slow-fast-slow regimes of change (Fig. 1b). The amount of change per generation is highest at intermediate allele frequencies, where the frequency of a beneficial allele could increase by more than 50 % over 25 generations. Analysis of human population genetic change over such a relatively short time period provides an oppor- tunity to consider the possibility of rapid human evolu- tion in the context of recent studies related to the convergence of evolutionary and ecological time. The question of extremely rapid evolution, i.e. evolution over ecological time scales, has received substantial attention over the last few years [32]. Traditionally, evolutionary and ecological timescales were considered to be very much distinct, but there are numerous studies docu- menting adaptive evolutionary change that have oc- curred well within the time span of the Columbian Exchange [33]. However, this line of work has not been explicitly extended to human populations as far as I know, and as such the admixture-introgression concep- tual framework outlined here may allow for the evolution-ecology synthesis to incorporate a human dimension. Testing the hypothesis The collection of uniquely admixed human populations found in the Americas represents an ideal laboratory to study rapid human adaptation and to test the hypothesis of adaptive introgression via the Columbian Exchange. To test this hypothesis, one would need to compare gen- ome sequences between putative ancestral populations with sequences characterized from admixed American populations. Comparison with genome sequences from ancestral source populations can be used to characterize the admixture contributions to New World populations at various levels: genome-wide and sex-specific ancestry proportions, local chromosomal ancestry assignments, and ancestry probabilities for individual nucleotide vari- ants (i.e., SNPs) when possible. Having characterized the overall ancestry contribution proportions for an admixed American population, one can then search for specific genomic regions (loci) or SNPs that significantly deviate from the expected patterns (Fig. 1c). This approach can be used to identify genomic loci that are enriched for a particular ancestry, or ancestry-specific haplotypes, sug- gesting the possibility that such regions were differen- tially retained in the admixed population based on their utility in the New World environment [7, 28–30, 34– 36]. This approach is analogous to the mapping by ad- mixture linkage disequilibrium (or admixture mapping) technique, whereby local deviations from genome-wide average admixture patterns are used to identify loci im- plicated in diseases that have different prevalences in an- cestral source populations [37]. Having identified ancestry-enriched loci (haplotypes) in this way, they can be further interrogated with respect to their rates of evo- lution as well as the functions of the genes encoded therein. Interestingly, two studies that were published while this manuscript was in revision both found an excess of African ancestry at the MHC locus in admixed Latin American populations [38, 39]. These results were taken to support the idea of adaptive introgression based on genetic resistance to infectious disease agents, and popu- lation genetic modeling was used to provide support for the role of selection in enriching for locus-specific Afri- can ancestry. Of course, selection is not the only evolu- tionary force that could change allele frequencies and lead to the appearance of locus-specific ancestry enrich- ment. Accordingly, it will be important to explicitly con- sider the role of other forces, including demography and genetic drift, in shaping patterns of locus-specific ances- try in admixed American populations. Indeed, the need to do so provides an opportunity for the development and application of admixture-specific population genetic Jordan Biology Direct (2016) 11:17 Page 4 of 8 models that go beyond the more straightforward sequence-based ancestry enrichment analysis outlined here. The potential for demography to shape patterns of ancestry also underscores the importance of choosing the best possible ancestral population for comparative analysis with admixed American populations. Fortu- nately, the increasing availability of population genomic sequence data from putative ancestral source popula- tions serves as a rich resource for this purpose. Implications of the hypothesis The hypothesis that the Columbian Exchange facilitated rapid adaptive evolution via admixture and introgression has implications for both basic research in human evolu- tion and for more clinical investigations into genetic de- terminants of human health. The potential for rapid human evolution is a topic of great interest [40, 41], and critical interrogation of the hypothesis proposed here could help to elucidate one specific mechanism by which such rapid adaptive evolution can be facilitated. It should be emphasized that adaptive evolution predicated upon differential retainment of ancestry-specific haplo- types could entail fairly subtle changes in allele frequen- cies along the mid-range of the frequency spectrum (Fig. 1b). Thus, it will be expected to occur far more rap- idly than complete fixation of new alleles introduced by de novo mutation. Analysis of admixed American populations using this conceptual framework has the potential to reveal human evolution in action. Current methods for detecting the signatures of adaptive evolution (i.e., selective sweeps) in human genome sequences are based on complex statis- tical models of sequence substitution and may lack power to unambiguously distinguish among different models of selection – e.g., hard versus soft selective sweeps, the role of de novo versus standing genetic vari- ation and the prevalence of polygenic selection [22, 31, 42]. Accordingly, there remains substantial controversy as to the relative importance of these different modes of adaptation in human molecular evolution [21, 42]. The alternative introgression-based framework for the detec- tion of potentially adaptive haplotypes that I have out- lined here can be considered to be agnostic with respect to these different models of the adaptation process as well as both conceptually straightforward and sensitive to relatively minor changes in allele frequencies [29]. To date, most population genetic studies of New World human populations have focused on ancestry, utilizing sequence variants as neutral markers of evolu- tionary lineages. Interrogation of the hypothesis pro- posed here calls for an explicit connection between human genetic ancestry and genetic determinants of health and fitness. The relationship between ancestry and genetic determinants of human health, often manifested as population-specific health disparities [43], is an important topic with serious public health implica- tions. For example, investigation into how admixed pop- ulations have been shaped by selection pressures imposed by infectious disease burden can provide insight into the genetic architecture of immune response [44]. Finally, an emphasis on the study of admixed genomes from across the Americas, which testing of the hypoth- esis articulated here necessitates, could provide for an important extension of current clinical genomic studies, the vast majority of which have focused on populations of European descent [45]. Reviewers’ comments Reviewer 1: Frank Eisenhaber, Bioinformatic Institute, Singapore The effort of the author to suggest the consequences of the Columbian Exchange for the human genome evolu- tion is laudable and deserves support. The scientific question of how the genomes of many today almost ex- tinct native American peoples survive as admixtures in genomes of European and African origin is of great im- portance form the evolutionary and historical point of view. Although I do fully agree with the general assess- ments, conclusions and proposals by the author, I am asking myself whether, at this preliminary point of time, we can speculate plausibly about certain new world characteristics that the natives were better adapted to compared with the arrivals from the other side of the Atlantic Ocean. For examples, have there been any in- fections/parasites originating from America that repre- sented a major problem for the colonizers and their imported slaves? Author’s response: The reviewer raises a very interest- ing point regarding the threat of infectious disease to European colonizers and African slaves from pathogens native to the Americas. In fact, it is thought that Native American populations had a far lower burden of infec- tious disease compared to European and African popula- tions. All of humanities major plagues – the black death, cholera, influenza, measles, mumps, smallpox, tubercu- losis and typhus – come from the Old World. The rela- tively low burden of infectious disease among Native American populations has been attributed to the fact that the Americas had far fewer (virtually none in fact) of the domestic animals that serve as sources of zoonotic infections [46], e.g., cows are the natural reservoir for measles, smallpox and tuberculosis, and pigs can harbor whooping cough and flu. The low burden of infectious disease in the Americas, and the related lack of genetic resistance mechanisms, left these populations extremely vulnerable to Old World pathogens and was the major cause of the population crash that occurred during the conquest of the Americas. Jordan Biology Direct (2016) 11:17 Page 5 of 8 One possible exception to this pattern is syphilis [47]. There is evidence to suggest that syphilis was brought to Europe by Columbus’ returning crew members, and the first recorded epidemic was from Naples, Italy in 1495. Shortly thereafter, syphilis quickly spread throughout Europe with devastating effects. Thus, it may in fact be the case that the burden posed to naïve European and African populations by syphilis in the New World also served as a selection pressure for adaptive introgression of resistant Native American haplotypes. The process of admixture as evolutionary process to gain fitness might be contrasted with the consequences of the process of (self-)isolation of populations as it is known, for example, for certain religious groups and heavily stratified societies (see the Indian caste system: “Genomic reconstruction of the history of extant popu- lations of India reveals five distinct ancestral compo- nents and a complex structure” Basu et al., PNAS (2016) doi: 10.1073/pnas.1513197113). It would be interesting to study whether at all or to which extent increasingly inbred mating might have detrimental effects on the populations’ fitness. Author’s response: This is another interesting point, which is entirely feasible although there is less direct evi- dence in support of it at this time. It is certainly possible that Native American populations had lower innate (genetic) resistance to infectious disease owing to lower genetic variability associated with bottleneck event(s) that accompanied their initial migration to the Americas from Asia [48]. High genetic diversity, among African populations for example, has been associated with in- creased resistance to infectious disease [49], and low di- versity could accordingly place populations at risk. Consistent with the idea raised by the reviewer, our own analysis of Native American populations from the Hu- man Genome Diversity project suggests that they have far lower overall genetic diversity than other populations from this same set of samples and/or from the 1000 Ge- nomes Project. However, this could also be a result of a bottleneck that occurred later as a result of contact with European populations [50]. Reviewer 2: Lakshminarayan Iyer, NIH,USA The article must be published. It is an original idea, un- tested and likely to provide new insights. This is a timely, well articulated and well defined hy- pothesis to test for the presence of partial selective sweeps of haplotypes derived from ancestral populations during the “Columbian Exchange”. It is only in the past 5 years or so that we are even beginning to understand the impact of admixtured populations across various re- gions and chronological times, leading to fascinating in- sights on the origins of modern populations, the presence of selective sweeps of alleles and even the impact of these on languages and cultural memes (e.g. PMID: 25731166, 26595274). In this backdrop of devel- opment, King’s proposal to test a very specific aspect on the presence of adaptive allele sweeps, from at least 3 or more ancestral populations that contributed to the admixtured populations of the modern Americas, is timely. The idea of using an introgression-based frame- work is interesting and perhaps quite agnostic as pointed out. Given that both the European and African popula- tions that entered the Americas themselves are derived from multiple ancestral populations, studying the above might further throw light on the evolutionary dynamics of those alleles or loci known to have been selected for in these populations prior to the “Columbian exchange” (e.g. 26595274). I agree that such a study is likely to re- sult in some really interesting insights on the impact of introgression between at least three distinct populations separated by many tens of thousand years. Author’s response: I appreciate the positive feedback from the reviewer. I agree that it will be important to take into account the fact that the Europeans and Afri- cans who came to the Americas during the course of the Columbian exchange were themselves derived from mul- tiple (and/or distinct) populations. It should be possible to tease apart the sub-continental admixture contribu- tions from such ancestral populations, and our own group is currently doing so for Afro-Colombian popula- tions in an effort to more precisely locate their origins within the African continent [51, 52]. The reviewers’ point also underscores the importance of choosing the most appropriate ancestral populations to perform the kind of ancestry enrichment analysis de- scribed here. For example, one may expect that European ancestry for Latino populations would be better modeled using Spanish ancestral populations (e.g., IBS from the 1000 Genomes Project) as opposed to the more widely used CEU sample, which corresponds to broadly distrib- uted Northern European ancestry. Our own preliminary results, suggest that this is in fact the case, and New World admixed populations can be distinguished by virtue of different European ancestry profiles. I have added a paragraph to the “Testing the hypothesis” section of the manuscript to address the need for analysis of ap- propriate ancestral populations. Reviewer 3: Igor B. Rogozin, NIH,USA The author hypothesized that the process of human gen- ome evolution stimulated by the Columbian Exchange was based on partial selective sweeps of introgressed haplotypes from ancestral populations, many of which possessed pre-evolved adaptive utility based on regional- specific fitness and health effects. I think that this is a promising hypothesis. The author suggested that in order to test this hypothesis, one would need to compare Jordan Biology Direct (2016) 11:17 Page 6 of 8 http://dx.doi.org/10.1073/pnas.1513197113 genome sequences between putative ancestral popula- tions with sequences characterized from admixed American populations. It is known that natural selection is not the only force that changes allele frequencies, other evolutionary forces include genetic drift, migration, mutation, and biased gene conversion. One potential problem is how to define “putative ancestral populations”, I think that only small (and potentially non-random) samples from putative an- cestral populations contributed to the Columbian Ex- change (the founder effect). The founder effect might confound the signal of adaptive evolution. However this may not have a substantial impact on the Columbian Ex- change, this needs to be evaluated using sequence data although the author may add a brief discussion of this problem to the paper. Author’s response: The reviewer raises important points about defining ancestral populations for enrich- ment analysis and the need to distinguish between the ef- fects of natural selection and demographic processes, both of which can change allele frequencies over time. The issue of the appropriate choice of ancestral popula- tions was also raised by Reviewer #2. Fortunately, there are more and more genomic data sets available from po- tential ancestral populations, and these data can be compared to genomic data from admixed American pop- ulations in order to determine the most appropriate an- cestral population for analysis. Nevertheless, the issue of founder effects from ancestral populations, which is en- tirely reasonable given the history of the conquest and colonization of the Americas, could still confound at- tempts to quantify changes in allele frequencies by com- paring modern populations. This fact, along with the need to distinguish selection from drift present both chal- lenges and opportunities for the development and appli- cation of population genetic approaches to this question, in addition to the more straightforward genome sequence analysis approaches described here. I have added a para- graph to the “Testing the hypothesis” section of the manu- script to address the points raised by the reviewer. Abbreviations SNP: single nucleotide polymorphism; ya: years ago. Competing interests The author declares that he has no competing interests. Author’s contributions KJ conceived of the hypothesis and drafted the manuscript. Author’s information KJ is Associate Professor in the School of Biology and Director of the Bioinformatics Graduate Program at the Georgia Institute of Technology (http://jordan.biology.gatech.edu). In addition to his research activities in computational genomics, he is also engaged in biotechnology capacity building efforts in Latin America. He co-founded the PanAmerican Bioinfor- matics Institute (http://panambioinfo.org) to apply bioinformatics and gen- omics approaches to challenges in public health and economic development in the Americas and serves as a scientific advisor to BIOS – the Colombian national center for bioinformatics and computational biology. Acknowledgements KJ was supported by BIOS Centro de Bioinformática y Biología Computacional (062-2014) and the Georgia Institute of Technology Denning Global Engagement Seed Fund (320000118). KJ would like to acknowledge members of his laboratory, along with his colleagues and friends from Colombia, who stimulated many of the ideas articulated here along with this particular line of research. Author details 1School of Biology, Georgia Institute of Technology, 950 Atlantic Drive, Atlanta, GA 30332, USA. 2PanAmerican Bioinformatics Institute, Cali, Valle del Cauca, Colombia. 3BIOS Centro de Bioinformática y Biología Computacional, Manizales, Caldas, Colombia. 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Gene. 2015;574(2):345–51. doi:10.1016/j.gene.2015.08.015. • We accept pre-submission inquiries • Our selector tool helps you to find the most relevant journal • We provide round the clock customer support • Convenient online submission • Thorough peer review • Inclusion in PubMed and all major indexing services • Maximum visibility for your research Submit your manuscript at www.biomedcentral.com/submit Submit your next manuscript to BioMed Central and we will help you at every step: Jordan Biology Direct (2016) 11:17 Page 8 of 8 http://dx.doi.org/10.1038/nature13408 http://dx.doi.org/10.1016/j.ajhg.2012.06.015 http://dx.doi.org/10.1016/j.tree.2013.08.003 http://dx.doi.org/10.1016/j.tree.2013.08.003 http://dx.doi.org/10.1371/journal.pgen.1003011 http://dx.doi.org/10.1038/nature10617 http://dx.doi.org/10.1038/nature10484 http://dx.doi.org/10.1371/journal.pgen.1004023 http://dx.doi.org/10.1371/journal.pgen.1004023 http://dx.doi.org/10.1038/nature11258 http://dx.doi.org/10.1534/genetics.113.160697 http://dx.doi.org/10.1038/srep12376 http://dx.doi.org/10.1086/520769 http://dx.doi.org/10.1016/j.cub.2009.11.055 http://dx.doi.org/10.1007/s00439-008-0541-5 http://dx.doi.org/10.1016/j.ajhg.2014.08.011 http://dx.doi.org/10.1101/gr.124784.111 http://dx.doi.org/10.1146/annurev-genom-082509-141523 http://dx.doi.org/10.1146/annurev-genom-082509-141523 http://dx.doi.org/10.1371/journal.pgen.1005847 http://dx.doi.org/10.1038/srep21766 http://dx.doi.org/10.1073/pnas.0707650104 http://dx.doi.org/10.1534/genetics.115.174912 http://dx.doi.org/10.1146/annurev.genom.4.070802.110356 http://dx.doi.org/10.1038/nrg3734 http://dx.doi.org/10.1038/nrg3734 http://dx.doi.org/10.1038/nrg2760 http://dx.doi.org/10.1371/journal.pntd.0000148 http://dx.doi.org/10.1371/journal.pone.0003199 http://dx.doi.org/10.1371/journal.pone.0003199 http://dx.doi.org/10.1098/rstb.2011.0312 http://dx.doi.org/10.1073/pnas.1112563108 http://dx.doi.org/10.1016/j.gene.2015.08.015 Abstract Background Presentation of the hypothesis Testing the hypothesis Implications of the hypothesis Reviewers Background The Columbian Exchange Adaptive introgression and rapid human evolution Presentation of the hypothesis Testing the hypothesis Implications of the hypothesis Reviewers’ comments Reviewer 1: Frank Eisenhaber, Bioinformatic Institute, Singapore Reviewer 2: Lakshminarayan Iyer, NIH,USA Reviewer 3: Igor B. Rogozin, NIH,USA Abbreviations Competing interests Author’s contributions Author’s information Acknowledgements Author details References work_447632ryfvepzkocy76rdmmm5u ---- JHEOR 175JHEOR | www.jheor.org 2017;5(2):175-82 | This is an Open Access article under the CC BY 4.0 license. The 500-year Cultural & Economic Trajectory of Tobacco: A Circle Complete Christopher A. Jones1,2,3, Amanda Wassel2, William Mierse4, E. Scott Sills5,6 1 Department of Biomedical Informatics, College of Health Solutions, Arizona State University, Phoenix, Arizona, USA 2 University of Vermont Health Network & Socio-Ecological Gaming Simulation Laboratory of the Community Development and Applied Economics Department; University of Vermont, Burlington, Vermont, USA 3 European Centre for International Political Economy (ECIPE), Brussels, Belgium 4 Department of History and Art History, University of Vermont, Burlington, Vermont, USA 5 Center for Advanced Genetics; Carlsbad, California, USA 6 Department of Obstetrics & Gynecology, Palomar Medical Center; Escondido, California USA Corresponding author: drsills@CAGivf.com Abstract Who smokes, and why do they do it? What factors discourage and otherwise reward or incentivize smoking? Tobacco use has been accompanied by controversy from the moment of its entry into European culture, and conflicting opinions regarding its potentially adverse influence on health have coexisted for hundreds of years. Its use in all forms represents the world’s single greatest cause of preventable disease and death. Tobacco was introduced to Europe by Christopher Columbus, who in October 1492 discovered the crop in Cuba. While the next four centuries would see tobacco as the most highly traded economic commodity, by 1900, the now familiar cigarette remained obscure and accounted for only 2% of total tobacco sales. Global tobacco consumption rose sharply after 1914 and became especially prevalent following World War II, particularly among men. Indeed, overall tobacco sales increased by more than 60% by the mid-20th century, and cigarettes were a critical driver of this growth. Cigarettes dominated the tobacco market by 1950, by then accounting for more than 80% of all tobacco purchases. In the absence of clinical and scientific evidence against tobacco, moral and religious arguments dominated opposition voices against tobacco consumption in the 1800s. However, by the mid-20th century, advancements in medical research supported enhanced government and voluntary actions against tobacco advertising and also raised awareness of the dangers associated with passive tobacco smoke exposure. Solid epidemiological work connecting tobacco use with “the shortening of life span” began to appear in the medical literature in the 1950s, linking smoking with lung cancer and related conditions. In subsequent years, these developments led to significant curtailment of tobacco use. This monograph explores aspects of the intersection of tobacco with themes of behavioral incentives, religion, culture, literature, economics, and government over the past five centuries. Keywords: tobacco; incentives; rewards; economics; health economics; society; religion; regulation; smoking JHEOR Jones CA, et al. 176 JHEOR 2017;5(2):175-82 | www.jheor.org INTRODUCTION A century-old riddle sets a peculiar challenge: To three fourths of a cross add a circle complete; Let two semicircles a perpendicular meet; Next add a triangle that stands on two feet; Then two semicircles, and a circle complete. Only one word in English could spell the answer to this geometry-savvy puzzle, as first framed in the 1907 George Welsh novel The Fragrant Weed. Cryptically packaging the familiar subject of tobacco as a playful riddle was not without good economic reason. Tobacco had already been the world’s single largest revenue-creating commodity for centuries. Long before Columbus set sail on the Santa Maria, this lant was used by native peoples for trade and in ritual in the Americas, and its popularity quickly spread after its introduction into Europe. Columbus himself described natives of the West Indies burning “perfumed herbs” and intentionally breathing the resulting smoke.1 Between 1492 and 1660, European explorers across the Americas recorded some 50 distinct native populations who used the tobacco plant. These foreign observers reported that tobacco was used for religious ceremonies and medicinal purposes, such as for toothaches, eye problems, and wounds.1 In the 1530s, during his travels near modern-day Montreal, Jacques Cartier described men carrying dried tobacco in bags and using pipes to “fill their bodies full of smoke, till that it commeth out of their mouth and nostrils, even as out of the tonnel of a chimny.” Tobacco use was not limited to the North American continent; the first protestant missionary in Brazil in the mid-1550s, Jean de Lery, sampled the tobacco of the local inhabitants and wrote that, “it seemed to satisfy and ward off hunger.”1 The phenomenal growth of interest in tobacco resulted from a lethal combination of addiction and profitability— factors which transformed tobacco into a cash crop on a scale scarcely seen before or since in world history. Yet, with tobacco’s immense popularity have come health consequences of an equally astounding magnitude. From a brain science perspective, tobacco is known to alter the hypothalamic-pituitary axis that controls fertility in addition to important growth and development functions. Tobacco is known to cause growth retardation and delayed brain development in infants born to mothers who smoke during pregnancy. Tobacco also predisposes populations to an increased likelihood and severity of costly chronic disease. We are well aware of the dangers of smoking. We may be less aware that the arc of tobacco’s cultural reception has been for centuries modulated by religion and government, tracing an unusual trajectory. In this work, we explore how these forces helped shape the modern cultural understanding of tobacco. ”PHYSIC” AND EARLY ADVOCACY FOR TOBACCO Tobacco entered the European marketplace around 1574 in part with the help of a popular medical text by Nicolas Monardes. This publication (and others of similar type) attempted to establish tobacco as a medical panacea. Disguised as a useful tool in contemporary medical practice, tobacco benefitted from an early association with professional medical practice and was robustly welcomed. While early shipment records (c.1600) show that some 25 000 pounds of tobacco were being imported into England every year, as the 17th century closed, this figure had increased to around 38 000 000 pounds annually.1 Although tobacco was warmly extolled as an essential cure-all by physicians and traders, there were contemporary detractors who voiced clear opposition to it. For example, King James I strongly denounced tobacco in his 1604 pamphlet JHEORJones CA, et al. 177JHEOR 2017;5(2):175-82 | www.jheor.org “A Counterblaste to Tobacco” which condemned the plant both for its negative spiritual and health effects. Smoking tobacco, James declared, was “sinning against God… [It was a] custome loathsome to the eye, hatefull to the nose, harmefull to the braine, dangerous to the lungs, and in the blacke stinking fume thereof, nearest resembling the horrible stigian smoke of the pit that is bottomelesse.”2 Yet such powerful statements by James I and other non-physicians had little effect on reducing the grip of tobacco upon the English people, and even less on the world beyond his realm. Up to the present day, tobacco has maintained a deadly hold on generations of men and women in every nation. As a commodity, it has funded wars, empires, expeditions, and helped build the very fabric of global economies. As accessory baggage on the worldwide tobacco train, numerous communicable diseases (polio, influenza, smallpox, syphilis, etc.) coming into and out of the “New World” brought millions to an early demise.1 Although cures for these ailments did eventually come in the form of medicines, vaccines, antibiotics, and better standards of living, human mortality curves shifted and unmasked lung cancer and other tobacco-related health problems as an important scourge upon human health for many generations. ECONOMIC & DEMOGRAPHIC DIMENSIONS In the United States, more than 16 million individuals now live with a disease caused by tobacco use including cancer, heart disease, and chronic obstructive pulmonary disease.3 The total annual economic impact of smoking in the United States in 2014 included about $170 billion in direct medical costs and about $156 billion in lost productivity.4 In the early 20th century, governments did little to discourage smoking. During World War II and the Korean Conflict, the U.S. Government provided no-cost cigarette allowances to soldiers stationed overseas while sharply discounting cigarette prices on U.S. military bases.5 In 1993, the U.S. Department of Veterans Affairs officially acknowledged the link between their past tobacco policies and negative health outcomes. As late as 2006, the U.S. Defense Department subsidized tobacco products for service members despite the U.S. Surgeon General’s report more than twenty years earlier detailing the dangers of smoking.5 The tobacco companies countered with the hollow innovation of “low tar” products and modified cigarette filter designs— marketing measures which had the unintended effect of attracting more women and minorities as first time smokers. In 1984, the U.S. Congress passed the Comprehensive Smoking Education Act which mandated changes in the way health warnings were displayed on cigarette packaging, including the statement “Smoking by pregnant women may result in fetal injury, premature birth, and low birth weight.” But have these anti-smoking measures worked? The results of this public health initiative, unfortunately, have been mixed: effectiveness in consumer education in the United States is likely positive, although the impact on tobacco consumption worldwide remains closely tied to monetary interests and is decidedly less encouraging. For example, in 2009 the highest percentage of male smokers over the age of 15 could be found in the Pacific island nation of Kiribati (more than 70%), followed by Greece at 63% and Indonesia at 61%. Likewise, the highest percentage of female smokers over age 15 was in Nauru (50%), followed by Austria (45%) and Kiribati (43%).6,7 Notably, China alone had >350 million smokers in 2003; their state-owned tobacco company manufactured 1.7 trillion cigarettes generating a profit of some two billion U.S. dollars—contributing 7.4% of central government revenue in China.8 While the Chinese government is aware of the negative health effects of tobacco and has taken official steps to restrict cigarette advertisements, reduce teen smoking, and discourage smoking in public, the sale of tobacco products curiously remains untaxed in China.8 India has the second largest population of smokers in the world. Indian health data from 2004 show that JHEOR Jones CA, et al. 178 JHEOR 2017;5(2):175-82 | www.jheor.org the direct medical costs to treat four major tobacco-related diseases was $1.2 billion, consuming 4.7% of the country’s total healthcare budget. Every year, about one million deaths occur in India due to tobacco-related diseases.9 Tobacco use thus poses an interesting economic dilemma that has remained unsettled for many years. While the individual and societal health costs of tobacco are undeniably high, the combined forces of corporate profits (including the impact of tobacco tax revenues and related lobbying) and personal addiction make it impossible to reduce tobacco use merely to a supply and demand equation. According to one model, increasing taxes to raise the retail price of a standard pack of cigarettes by 42% would result in a 9% reduction in daily smoking (66 million fewer smokers and 15 million fewer smoking-attributable deaths among adults in 2014). Revenue derived from tobacco sales would increase by 47%, yielding an additional $190 billion for government health spend.10 Against this background, more recent tactics of incentives against (or disincentives for) smoking have emerged with most jurisdictions requiring warnings and images on cigarette packaging, state taxes imposed on purchases, and even clinical programs that offer incentives to palliate tobacco users through short-term goals, such as cash rewards offered for every week of pregnancy that is completed smoke-free. RELIGIOUS THOUGHT AND THE “TOBACCO CULTURE” Even when not specifically crafted for public policy purposes, incentives may be used to promote positive behavior. This notion certainly preceded tobacco’s arrival in European culture and famous examples survive in spiritual thought, art, and architecture. Among the most visually striking “incentives” are images developed in the 12th century as decoration for churches, particularly those on the pilgrimage route to Santiago de Compostela. The Last Judgement was a common theme in these depictions, and that at Saint Lazare at Autun by Gislebertus offers perhaps a representative illustration. It occupies the arched space (tympanum) above the structure’s main entrance. The central figure is Christ the Judge presented as isolated from the rest of the scene, impassive and uninterested in what happens around him. He of course needs no incentive, but appears as one. To his right are the saved, to his left the damned, and below are seen souls awaiting the final judgment. The immediate message seems apparent, “At the moment of the Last Judgment, it will be too late to repent.” Those who have lived a good life will join the ranks of the saved, while those who have not repented will face the demons of hell. Monstrous forms hint of the pains that await the damned. Among the souls to be weighed are those of clergy and nobles, as well as those of more modest folk. All face the same fate, to be weighed and, if found wanting, to be condemned. The visual message is easy to read, and its intention is clear. To escape the horrors of hell, the soul must be judged to be pure. The behavior being promoted is that which corresponds to church teaching, and it is only by practicing such behavior that eternal damnation is to be avoided. Yet, Christ is shown as the highest incentive figure just as the demons and the hell represent disincentives. The message conveyed by this magnificent artwork can be summarized as: live a good Christian life, and you may spend eternity in heaven with your Savior.11 The Roman Catholic Church does not condemn smoking, but considers excessive smoking to be sinful, as described in the Catechism:12 “The virtue of temperance disposes us to avoid every kind of excess: the abuse of food, alcohol, tobacco, or medicine.” Jehovah’s Witnesses have not permitted any active members to smoke since 1973, and their literature warns about physical and spiritual dangers of smoking.13 These directives were later expanded to include electronic cigarettes.14 Seventh-day Adventists, an international non-conformist denomination, have since their foundation in 1863, maintained a distinctive healthcare model for their members. The lifestyle has included vegetarian diet and abstinence from tobacco and other harmful substances.15,16 Moreover, this religious group has called for governments to enact policies that include a uniform ban on all tobacco advertising, stricter laws prohibiting smoking in non-residential public places, more aggressive and JHEORJones CA, et al. 179JHEOR 2017;5(2):175-82 | www.jheor.org systematic public education, and substantially higher taxes on cigarettes.17 The founder of the Latter Day Saint (LDS, Mormon) movement, Joseph Smith, recorded that on February 27, 1833 he received a revelation which addressed tobacco use. It is commonly known as the Word of Wisdom (Section 89 of the Doctrine and Covenants), and prohibits the smoking or chewing of tobacco. While initially regarded only as a guideline, this was eventually incorporated into official LDS Church policy and is now also observed to varying degrees by other LDS denominations. The effects of these practices have been extensively studied and the cancer rate (all types) for male LDS members is nearly 25% less than the comparable national rate. In addition, there appears to be a 50% lower rate of cancers associated with cigarette smoking among LDS men.18 There remains an extraordinarily high rate of tobacco use in southeast Asia.19 Findings from national adult tobacco studies reveal that very few daily users of tobacco plan to discontinue its use. In predominantly Buddhist Cambodia, faith-based tobacco control programs have been implemented where, under the 5th Precept of Buddhism which proscribes addictive behaviors, monks were encouraged to quit tobacco and temples have been declared smoke-free. In one nationwide study on tobacco use throughout Cambodia, investigators found that most individuals (n=13 988) favored Buddhist monks not using any tobacco whatsoever and that the Wat (temple) should be smoke-free. Thus, anti-tobacco sentiments figure prominently in the belief system of Cambodian adults and could be helpful in augmenting anti-tobacco campaigns in this region.20 Likewise in South America, religiosity has been identified as a strongly protective factor against tobacco consumption and use of other addictive substances among Brazilian university students.21 Islam was historically neutral towards smoking, but as health dangers emerged many leaders within influential mosques began to argue that it was “markrooh” (discouraged) or even “haram” (prohibited). Because such sentiments, if widely held, would be catastrophic to the tobacco economy as well as to collective human addictions, Islamic scholars sympathetic to tobacco have been enlisted to argue against strict prohibitions; Islamic theology has also been combed to provide interpretations of the Koran that are friendlier to tobacco. “The industry has sought to distort and misinterpret the cultural beliefs of these communities and to reinterpret them to serve the industry’s interests,” noted Kelley Lee of Simon Fraser University, one of the authors involved in researching this topic. “All to sell a product that kills half of its customers.”22 Populations with large Islamic influences remain critically important to transnational tobacco corporations because they represent growth markets where smoking rates are likely to rise. In contrast, recruitment of new smokers in the Middle East has been less effective among Jewish males, where tobacco uptake has been relatively low for several years.23 In parallel, corporate interests perceive Islam as developmentally antagonistic to tobacco markets where demographic features offer relatively large and young populations of millions of potential future customers. To maximize penetration into these emerging markets, the tobacco industry has mobilized alliances to negate any regulation hostile to its commercial interests,24,25 and began to frame antismoking views within the Islamic community as eccentric and fanatical.26 Not surprisingly, such efforts to find culturally appropriate measures to support tobacco use conflict with the provisions of the World Health Organization’s Framework Convention on Tobacco Control.26 Evidence exists to support the association of positive cultural and artistic smoking portrayals with youth smoking initiation, thus captivating new tobacco consumers who are likely to purchase the product for decades. In Iran, the ten most commercially successful films released over the past 30 years were recently assessed to measure this effect. The proportion of Persian movies depicting tobacco use was 36% in 1982-1991, 60% in 1992-2001 and 74% in 2002-2011, and the mean proportion of each movie’s running time where smoking was JHEOR Jones CA, et al. 180 JHEOR 2017;5(2):175-82 | www.jheor.org shown also grew significantly during this period.27 Perhaps more alarmingly, while the depiction of tobacco use in American (G-rated) films seems to be decreasing, parents should be aware that nearly half of feature “films for children” normalize tobacco use and fail to convey its long-term health effects to impressionable audiences.28 In social media, researchers (including author CJ) found that 80% of e-cigarette related tweets in the Twittersphere were found to be “bots,” created by e-cigarette companies, targeting kids and purporting to be other kids sharing their “success” stories with e-cigarettes.29 CONCLUSIONS The most recent information regarding worldwide smoking shows that about 80% of smokers are men and many of them live in developing countries. Tobacco remains very big business, no matter what scale is used— nearly 20% of the world population now smokes cigarettes. While the prevalence of tobacco use has plateaued or diminished in countries with advanced economies, the rest of the world shows an uneven consumption pattern with only 10 countries accounting for 60% of all tobacco use worldwide—a list led by China. Many interlocking cultural and economic factors are responsible for this arrangement. Tobacco markets have not been financially satisfying in some locations. In Australia, smoking is in decline with 2011–13 data revealing only 16% of the adult population smokes—down from a rate of 22.4% in the previous decade. In the USA, smoking rates have fallen precipitously over 40 years, from 42% to about 20% of adults (1965 vs. 2006). When adequately resourced, the smoking cessation efforts for many states have shown a nearly immediate return on investment (ROI), with every 1 USD invested achieving 3-5 USD in downstream savings, especially in the area of maternal-fetal medicine, not to mention tobacco as a gateway drug to many other substances, including alcohol and opiates that have reached epidemic levels of misuse. It is difficult to overstate the impact of socio-cultural elements of art and religion in fashioning health behaviors among young adults. Young adults are the most likely age group to take up smoking, with a marked decline in smoking rates as populations age, become better educated, and enter employment. Tobacco use is inversely associated with socioeconomic status, with the most disadvantaged quintile of the population registering a rate of tobacco consumption more than double that of the most socioeconomically advantaged “top quintile.” Nowadays tobacco has evolved—its use in language has been replaced with terms like “e-cigarette.” Smoking is part of our everyday culture; it is even a metaphor for describing beauty. Poet Laureate Donald Hall reminds readers of the “dead metaphor,” and the circle complete has left more dead than all the combat and civilian casualties from all wars over the past century. Those least able to afford tobacco and its ill health consequences remain paradoxically the most likely to purchase tobacco products. It therefore appears that the old reservations concerning tobacco by James I were correct, after all; in this new century, we have indeed come “full circle.” While our analysis merely scratches the surface of how interconnected tobacco is to history, economy, religion and culture, it is hoped that by highlighting these issues we may find better ways to navigate a healthier path on the circle of life. CONFLICT OF INTEREST The authors report no conflict of interest. ACKNOWLEDGEMENTS The authors wish to acknowledge the support of the Vermont Tobacco Evaluation and Review Board and Erin Hurley, Eric Clark and Rick Valenta for their helpful collaborations. JHEORJones CA, et al. 181JHEOR 2017;5(2):175-82 | www.jheor.org REFERENCES 1 Mancall PC. Tales Tobacco Told in Sixteenth-Century Europe. Env His 2004;9(4):648-78. 2 James I (of England). A Counterblaste to Tobacco (public domain). Univ Texas Library: https://www.laits. utexas.edu/poltheory/james/blaste/blaste.html. Accessed 29 August 2017. 3 U.S. Surgeon General. The Health Consequences of Smoking—50 Years of Progress (Executive Summary). U.S. Department of Health & Human Services, Public Health Service, Office of the Surgeon General (Rockville, MD) 2014:1-36. 4 Xu X, Bishop EE, Kennedy SM, Simpson SA, Pechacek TF. Annual healthcare spending attributable to cigarette smoking: an update. Am J Prev Med 2015;48(3):326-33. 5 Bedard K, Deschênes O. The Long-Term Impact of Military Service on Health: Evidence from World War II and Korean War Veterans. Am Econ Rev 2006;96(1):176-94. 6 World Health Organization Report on the Global Tobacco Epidemic, 2008. United Nations Press, WHO 2008: 8. 7 World Health Organization Report on the Global Tobacco Epidemic, 2015. United Nations Information Office: http://www.who.int/tobacco/surveillance/policy/country_profile/kir.pdf Accessed 29 August 2017. 8 Hu TW, Mao Z, Ong M, et al. China at the crossroads: the economics of tobacco and health. Tob Control 2006;15 Suppl 1:i37-41. 9 John RM, Sung HY, Max WB, Ross H. Counting 15 million more poor in India, thanks to tobacco. Tob Control 2011;20(5):349-52. 10 Goodchild M, Perucic AM, Nargis N. Modelling the impact of raising tobacco taxes on public health and finance. Bull World Health Organ 2016;94(4):250-7. 11 Snyder J. Medieval Art: Painting-Sculpture-Architecture, 4th-14th Century. Prentice-Hall 1988:287 (Figs. 358 & 359). 12 Vatican Library: Catechism of the Catholic Church (Part III, sec. 2). http://www.vatican.va/archive/ccc_ css/archive/catechism/p3s2c2a5.htm. Accessed 29 August 2017. 13 Watchtower [newspaper]. Awake! Why Quit Smoking? March 22, 2000:4-7. 14 Watchtower [newspaper]. What Is God’s View of Smoking? June 1, 2014:4. 15 Eklöf M. Medicine on mission: The international health reform of Seventh-Day Adventists and their health care facilities in Sweden. Sven Med Tidskr 2008;12(1):119-41. 16 McKenzie MM, Modeste NN, Marshak HH, Wilson C. 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PLoS One 2016; 11(7):e0157304. work_46bfaidoozdibj66mmqvgypdqu ---- wp-p1m-38.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-38.ebi.ac.uk no 218201915 Params is empty 218201915 exception Params is empty 2021/04/06-02:09:28 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. Message ID: 218201915 (wp-p1m-38.ebi.ac.uk) Time: 2021/04/06 02:09:28 If you need further help, please send an email to PMC. Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_476nlhgp25afdob63fst4tx5ki ---- Hindawi Publishing Corporation Journal of Oncology Volume 2011, Article ID 408104, 8 pages doi:10.1155/2011/408104 Review Article Tobacco and the Escalating Global Cancer Burden Richard F. Oppeltz and Ismail Jatoi Department of Surgery, The University of Texas Health Science Center, Mail Code 7738, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA Correspondence should be addressed to Ismail Jatoi, jatoi@uthscsa.edu Received 14 December 2010; Revised 28 March 2011; Accepted 10 May 2011 Academic Editor: Venkateshwar Keshamouni Copyright © 2011 R. F. Oppeltz and I. Jatoi. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The global burden of cancer is escalating as a result of dramatic increases in the use of tobacco in the developing world. The use of tobacco is linked to the development of a broad variety of cancers, mainly lung cancer, the single most common cancer in the world. Tobacco smoking-attributable deaths extends beyond cancer and include stroke, heart attack and COPD. Widening disparities in cancer-related mortality have shifted towards a more dramatic burden in the developing world. Appropriate interventions must be implemented to reduce tobacco use and prevent global mortality that has escalated to epidemic levels. Tobacco control policies, including public health advertisement campaigns, warning labels, adoption of smoke-free laws, comprehensive bans and tax policies are highly effective measures to control tobacco use. Clinicians and academic institutions have to be actively committed to support tobacco control initiatives. The reduction in cancer related morbidity and mortality should be viewed as a global crisis and definitive results will depend on a multilevel effort to effectively reduce the burden of cancer, particularly in underprivileged regions of the world. 1. Introduction The global burden of cancer is escalating, largely due to dra- matic increases in the use of tobacco in less developed nations [1]. Indeed, overall cancer rates appear to be increasing in developing countries, even while they remain generally stable or show small decreases in many industrialized countries [2, 3]. Thus, global changes in tobacco use may eventually produce large disparities in cancer-related mortality rates between the developed and less developed countries of the world [4]. The purpose of this paper is to highlight the trend towards increased tobacco use and the increasing cancer burden in developing countries and suggest steps that might be taken to reverse this alarming trend. Tobacco was widely used by the Mayans and other Native Americans well before Christopher Columbus introduced it to Europe in 1492. Within 150 years after its introduction to Europe, tobacco use was common throughout the world. Over the centuries, the methods of tobacco usage have changed considerably. In the 18th century, snuff held sway; the 19th century was the age of the cigar; the 20th century saw the rise of the manufactured cigarette and with it a greatly increased number of smokers [5]. Although the worldwide use of tobacco has steadily increased since the 16th century, early public statements showed its disapproval as stated by James I of England in his Counterblaste to Tobacco in 1604: “Smoking is a custom loathsome to the eye, hateful to the nose, harmful to the brain, dangerous to the lungs, and in the black, stinking fume thereof nearest resembling the horrible Stygian smoke of the pit that is bottomless.” Thus, even though its health risks have been acknowledged for centuries, tobacco use throughout the world continues to increase. Most people who use tobacco regularly do so because of their addiction to nicotine, a major component of cigarettes. Although the majority of users express a desire to reduce their use or stop entirely, overcoming the addiction is difficult and may require both pharmacologic and behavioral treatments. Recent research has clarified the addictive nature of nicotine, and it appears to be similar to that of the opiates, cocaine, or other illicit drugs [6, 7]. Environmental factors likely also contribute to the increased use of cigarettes. For many, the behavior of smoking is not simply a matter of addiction, nor one of poor self-image, but also occasionally to underlying mental illness [8]. mailto:jatoi@uthscsa.edu 2 Journal of Oncology 2. Tobacco-Associated Cancers The association between tobacco and lung cancer was initially demonstrated by Doll and Hill in the 1950s in the UK [9]. Since then, additional case-control studies [10] and prospective cohort studies [11] have all affirmed the association between tobacco and the development of lung cancer. Indeed, lung cancer was rare in the early decades of the 20th century, but with the increase in smoking tobacco, it has become an alarming epidemic. The tobacco hazard, although clearly linked to the development of lung cancer, also causes an increased risk of several other cancers, notably oral, larynx, pharynx, esophagus, stomach, liver, pancreas, kidney, bladder, uterine cervix cancers, and myeloid leukemia [12]. There is a clear dose-response relationship between cancer risk and tobacco use. A lifetime smoker has a risk 20–30 times greater than of a nonsmoker [13]. More than 4,000 chemicals have been identified in tobacco smoke, and some 60 are known or suspected carcinogens [14]. Each cigarette brings approximately 10 mg of soot, tar, ash, phenols, benzpyrene, hydrogen cyanide, formaldehyde, and radioactive polonium 210 into the lungs of the smokers [5]. 3. The Global Problem Worldwide, cancer is responsible for 1 out of every 8 deaths (more than HIV/AIDS, tuberculosis and malaria combined [15]), and tobacco use is responsible for one-third of all cancer-related deaths [16]. The International Agency for Research on Cancer (IARC) estimates that there were approximately 12.7 million new cases of cancer diagnosed in the world in 2008, and 7.6 million deaths attributed to it [17]. Furthermore, tobacco is responsible for 87% of all deaths attributable to lung cancer [18], now the single most common cancer in the world. It is estimated that by 2030 lung cancer will be the sixth most common cause of death in the world, compared with its current ranking of ninth [19]. Tobacco smoking-attributable illness extends beyond cancer and includes stroke, heart attack, and COPD. Indeed, total tobacco-attributable deaths are projected to rise from 5.4 million in 2005 to 6.4 million in 2015 and to 8.3 million in 2030 [19], with an estimated 600,000 deaths attributable to second-hand smoke [20]. These projections are based on models that show a three- to four-decade lag between the rise in smoking prevalence and the increase in smoking- attributable mortality that results from it [21]. Yet, if appropriate measures to control tobacco were implemented, a large proportion of these deaths could be averted. A number of indirect methods to estimate the mortality attributable to tobacco use have been developed; however, limitations related to specific countries and age population groups have been noted in the literature [22–25]. Unless there is widespread cessation of smoking, approxi- mately 450 million deaths will occur as a result of smoking by 2050, and most of these will occur in current smokers [26]. For instance, the global burden of lung cancer has shifted significantly from approximately 31% of cases occurring in developing countries, to now up to 55% occurring in these countries [27]. This makes the widening disparities in cancer-related mortality between developed and developing countries even more tragic. Indeed, the World Health Orga- nization (WHO) estimates that 40% of all cancers diagnosed today could have been prevented, partly by maintaining healthy diet, promoting physical activity, and preventing infections that may cause cancer, but largely through tobacco control [28]. Although the contribution of tobacco use to disease and death is well known, less attention has been given to the ways in which tobacco increases poverty and broadens social inequalities [29]. For example, in Vietnam, the amount spent on cigarettes ($US 416.7 million) is enough to feed 10.6– 11.9 million people per year [30]. Furthermore, it has been reported that in China, poor individuals may spend up to 60% of their income on cigarettes, taking away money from food and children education [31]. Serious environmental problems are also associated with tobacco production, which requires the greater use of fertilizers and pesticides and massive deforestation for curing tobacco leaves. One tree is wasted for every three hundred cigarettes produced, and it is estimated that land used for tobacco cultivation worldwide could potentially be used to feed about 10 to 12 million people [32]. As in other agricultural sectors, child labor is prevalent in the tobacco farms, particularly in the poorer areas, where up to 80% of children are missing school and/or undertaking hazardous tasks due to farm work [33]. Currently, smoking imposes a huge economic burden in developed countries, responsible for 15% of the total healthcare costs [34]. Developing countries, with higher population growth rates, are not prepared to cope with such increases in their healthcare expenditures. 4. Tobacco Industry In many industrialized countries, tobacco use appears to be declining, largely due to the diligent efforts of public health officials. In response to these declines, the tobacco industry is now targeting third world markets, not only to expand their markets, but also as a source of less expensive tobacco. The tobacco industry includes some of the most powerful transnational companies in the world. These companies sell about six trillion cigarettes each year, which accounts for the largest share of manufactured tobacco products, comprising 96% of the total value sales [35]. The industry is highly concentrated within a handful of firms. The global tobacco market, valued at US$ 378 billion, grew by 4.6% in 2007 and by the year 2012 is expected to increase another 23%, reaching US$ 464.4 billion [36]. China is the biggest tobacco market, based on total cigarettes consumed. There are some 350 million smokers in China who consume around 2,200 billion cigarettes a year, or about 41% of the global total. However, the industry in China is state owned. Outside of China, the four largest publicly- listed international tobacco companies account for about 46% of the global market. Although the tobacco compa- nies have experienced declines in profits in industrialized Journal of Oncology 3 countries, their overall profits are increasing, driven by world population growth, particularly in Asia. The tobacco companies have reacted to stagnating demand on their traditional markets in basically three ways: consolidation (dominating the business by few but very influential com- panies), diversification (by producing low- and high-quality cigarettes and geographic diversification), and increasing productivity [37]. Worldwide, even if the prevalence of tobacco use falls, the absolute number of smokers will increase due to the huge population of the developing world [38]. The giant multinational cigarette companies generally find that the political and social climate in the developing world is conducive to their business [39]. Governments in these countries use tobacco taxation as a source of much needed revenue and, therefore, do very little to discourage tobacco use. Furthermore, people in the developing world are generally much less knowledgeable about the health risks associated with cigarettes, and there exist very few anti- smoking campaigns, with tobacco products often carrying no health warnings [40]. In Pakistan, for example, health warnings, even if available, tend to be very vague and poorly understood [41]. High-tar cigarettes, banned in developed countries, continue to be sold in the developing world. For example, nicotine contents for Indonesian kreteks or clove cigarettes are between 1.7 and 2.5 mg per stick compared with <0.05 and 1.4 mg per stick for cigarettes sold in the USA [42]. Yet, the tobacco companies are continuing their market- ing efforts in the industrialized countries as well. Although no other consumer product is more dangerous or kills as many people as does tobacco, it still remains the most advertised product in the USA, with estimated advertising expenditures in the tens of billions of US dollars every year [35]. Facing global antitobacco forces, the tobacco industry is already moving beyond what they refer to as “light” and “mild” cigarettes to a new generation of tobacco prod- ucts referred to as “potential-reduced exposure products” (PREPs) [43]. These products, which have been in develop- ment for decades, are the next step after filters and low- delivery “light” and “mild” cigarettes. The essential idea behind PREPs is that they will deliver the levels of nicotine required for a smoker’s addiction with less (but some) of the toxins associated with smoking [44]. Yet, these products clearly are associated with alarming health risks, downplayed by the tobacco industry. In May, 1999, researchers of the World Bank’s Health, Nutrition and Population sector published a paper entitled “Curbing the Epidemic: Governments and the Economics of Tobacco Control.” This document concluded that tobacco control is not only good for health, but also good for the economy. Yet, multinational tobacco companies have attempted to use their own “economic impact studies” to convince governments that, contrary to the World Bank’s conclusion, tobacco use benefits the economy. Thus, the tobacco industry continues its diligent efforts to undermine any threat to its profits. There are several investigators who have argued that the tobacco industry propagates disinformation, manipulates research, and generates faulty information concerning the effects of tobacco use and second-hand smoke [7, 45]. 5. The Growing Problem in the Developing World Worldwide, cigarette consumption is increasing at a rate of about 3% annually. In Asia, Southern and Eastern Europe, and developing countries, tobacco use is increasing at about 8% per year. Yet, in some industrialized countries, smoking rates are decreasing at about 1% a year, largely due to the implementation of significant anti-tobacco programs. As with all other epidemics involving a major behavioral component, the exact timing, duration, and magnitude of the smoking epidemic will vary significantly from one country to another. In China and many other developing countries, the rate of tobacco-related deaths is rising rapidly. China is now beginning to face the detrimental consequences of tobacco use, as many millions of individuals who began smoking in adolescence are now aging. Yet, it will be around 2030 before the epidemic of tobacco-related deaths peaks in China at the level achieved in the United States in 1990 [46]. Indeed, lung cancer rates in China have already been increasing about 4.5% a year. These trends reflect significant policy deficiencies towards tobacco use in developing countries. Most cigarettes are now consumed and produced in Asia. China alone produces close to 40 percent of world total, followed by India, Brazil, and USA (Figure 1). Neither tobacco nor cigarettes are a homogeneous product. Different conditions in the tobacco growing areas, (type of soil, rainfall, irrigation, and climate) handling and processing, ultimately will influence the quality of the leaf and the smoking product. Most manufacturers use a blend of different tobaccos in their product. However, the tobacco’s leaf quality and additive contents will affect the particular taste of a cigarette brand and certainly the price [47]. The increasing incidence of cancer in developing coun- tries reflects a transition in the global burden of disease away from one previously dominated by infectious diseases. This shift is also partly due to the ageing of the population and public health interventions such as vaccinations and the provision of clean water and sanitation in the developing world, all of which have served to reduce the burden of infectious diseases. Also some of the environmental, social, and structural changes linked to the transformation of a country from agrarian to industrial and then to a postindustrial state may lead to increased longevity in the population. As cancer is more common in the older age groups, cancer rates are expected to increase accordingly. Yet, public health interventions can effectively lower the cancer rates. Low- and middle-income countries, faced with the tobacco epidemic, can learn from the tobacco-control successes in high-income countries by enacting cost-effective tobacco-control policies. Such policies can effectively reduce the burden of cancer. 4 Journal of Oncology 10,000–99,999 1,000–4,999 Less than 1,000 No tobacco grown No data Land devoted to growing tobacco Area in hectares, 2004–2007 100,000 or more 5,000–9,999 Tobacco grown on more than 0.25% of agricultural land, 2005 Figure 1: World land devoted to growing tobacco. The Tobacco Atlas, third edition. “Reprinted by the permission of the American Cancer Society, Inc., The Tobacco Atlas, 3rd Edition. American Cancer Society 2009, http://www.cancer.org/. All rights reserved.” 6. Global Approaches to an Escalating Cancer Burden Many interventions (public health advertising campaigns, warning labels on tobacco products, etc.) that were devel- oped in the industrial world to curb tobacco use should be urgently implemented in the developing world. Interventions to reduce tobacco use may not only avert a large burden of unnecessary deaths, but also save governments huge health care costs. To prevent death or morbidity from cancer, interventions should target behaviors or risk factors that are responsible for tobacco use, and these interventions should be cost effective [48]. The Disease Control Priorities Project (DCPP), a joint effort of the Fogarty International Center of the US National Institutes of Health (NIH), World Health Organization (WHO), and The World Bank, was launched in 2001. This project aims to assist decision makers in developing countries find affordable, effective interventions to improve the health and welfare of their populations [49]. The spirit of international cooperation is exemplified in The Tobacco Control Country Profiles database, a data collection initiative led by the American Cancer Society, the World Health Organization (WHO), and the Centers for Disease Control and Prevention. It represents a worldwide information system to support global tobacco control efforts [50]. The World Health Organization (WHO) has led interna- tional strategies to eradicate tobacco use. The WHO Frame- work Convention on Tobacco Control (FCTC), the first global treaty in response to the tobacco epidemic, adopted in 2003, sets the foundation for price and nonprice population- based control interventions to reduce both demand for and supply of tobacco products and provides a comprehensive direction for tobacco control policy at all levels (Table 1). As of October 2010, 172 countries have ratified the treaty, representing 87.3% of the world’s population. Up to a 21% reduction in smoking prevalence can potentially be achieved by implementing important interventions, such as increased taxes on tobacco products, enforcement of smoke-free workplaces, controls on packaging and labeling of tobacco products, and a ban on tobacco advertising, promotion, and sponsorship [51]. The Tobacco Control Program of the WHO was devel- oped in response to the globalization of tobacco use. It is based on the principles of the FCTC, provides data- supported effective measures for tobacco control at all levels, and launches an annual global report summarizing the most current status of the application of those strategies. In 2008, WHO introduced a package of principles under the acronym of MPOWER intended to assist in the country-level implementation of effective measures to reduce the demand for tobacco. Table 2 summarizes those key points. There are dozens of more national and international nongovernmental organizations which address tobacco con- trol as part of their activities and numerous additional partner organizations that promote tobacco control among their initiatives [35]. Despite significant improvements worldwide in cancer diagnosis and treatment, much still remains to be done [52]. Cancer is a global challenge. Health-oriented resources should be allocated to collect accurate cancer data [53]. In http://www.cancer.org/ Journal of Oncology 5 Table 1: Key policy provisions of the WHO framework convention on tobacco control [8]. FCTC article no. Policy 6 Price and tax measures to reduce demand. 8 Protection from exposure to tobacco smoke. 9 Regulation of the contents of tobacco products. 10 Regulation of tobacco product disclosures. 11 Controls on packaging and labeling of tobacco products. 12 Programs of education, communication, training, and public awareness. 13 Bans on tobacco advertising, promotion, and sponsorship. 14 Programs to promote and assist tobacco cessation, and prevent and treat tobacco dependence 15 Elimination of illicit trade in tobacco products. 16 Measures to prevent the sale and promotion of tobacco to young people. 17 Provision for support for alternative crops to tobacco. 20 Provision for an epidemiologic monitoring system. 22 Cooperation among the parties to promote the transfer of technical and scientific expertise on surveillance and evaluation. Table 2: World Health Organization MPOWER key points [1]. Monitor tobacco use and prevention policies. Protect people from tobacco smoke. Offer help to quit tobacco use. Warn about the dangers of tobacco. Enforce bans on tobacco advertising, promotion, and sponsorship. Raise taxes on tobacco. developing countries, cancer registries are perceived as a luxury and rarely provided sufficient resources. International scientific societies have defined standards for cancer data collection, starting with a hospital-based registry which can be the first step towards the formation of a population- based cancer registry. The major aim of a cancer registry is to produce and interpret data to develop country-specific research protocols and cancer control plans [54]. In high-income countries, comprehensive bans on all advertising, promotion, and sponsorship protect people from industry marketing tactics and decrease tobacco con- sumption by approximately 7%. It has been suggested that these preventive measures might be twice as effective in low and middle-income countries potentially reducing global cancer mortality rates [55, 56]. The Family Smoking Preven- tion and Tobacco Control Act, a United States federal law that gives the Food and Drug Administration (FDA) the power to regulate the tobacco industry, was signed into law on June 22, 2009 by President Barack Obama. The Tobacco Control Act requires that cigarette packages and advertisements have larger and more visible graphic health warnings (including nine new textual warning statements and color graphics depicting the negative health consequences of smoking) and a prohibition on the manufacture of products that use the terms “light,” “low,” “mild”, and similar descriptors [57]. Tax policies that raise the price of tobacco products are the single most effective approach for reducing demand, since consumption is highly influenced by the extent to which smokers can afford to purchase cigarettes [58]. Price increases are especially effective against the initiation of smoking in youth and motivating addicted smokers to quit [59]. A 10% price increase may cause a 4% drop in tobacco consumption in high-income countries and an 8% drop in low- and middle-income countries, in addition to increasing tobacco tax revenue [60]. Additional price cap regulations (wherein a cap is placed on the pretax cigarette manufacturers’ price) limits excess profits for the tobacco industry and increases government revenue [61]. The magnitude of the price increase is one of the most important predictors of an intention to quit/smoke compared with the average cigarette price. However, the availability of alternative (cheaper) cigarette sources may reduce but would not eliminate the impact of higher prices/taxes on the expected intention to stop smoking [62]. Illegally sold cigarettes evade taxes, and indeed, smugglers put cheap cigarettes into the hands of those most vulnerable, the developing countries, where those activities have been rising exponentially. Tobacco has now become the world’s most widely smuggled legal substance. The World Health Organization estimates that as many as 25% of all cigarettes sold in the world are smuggled. For the international gangs that organize the traffic, it is even more profitable than drug smuggling [63]. Cessation programs have been shown to provide benefits to certain populations [64]. Cessation programs have a role at all levels of the health workforce, including primary care, health specialists, and smoking cessation specialists. Adoption of smoke-free laws, included in the article 8 guidelines of the FCTC, has been shown to reduce hospital admission for heart attacks and results in an overall decrease in acute coronary events [65]. Multiple successful examples of countries and cities around the world that have implemented smoke-free laws support the fact that with adequate planning and resources, tobacco-free enforcement protect health and profits the economy [66]. Latin America remains at the forefront of global progress with Colombia, Guatemala, Paraguay, Peru, and Honduras recently added to that growing list [67]. The European Union is proposing a full-scale ban on branded cigarettes, forcing tobacco companies across the continent to sell their products in generic, plain packaging. Worldwide, 25 countries already switched from text to graphic health warnings [68]. International organizations and governments have found certain constraints and barriers to succeed in the war against tobacco: lack of adequate technical and financial resources and capacities for tobacco control; weakness or lack of effective national legislation on tobacco control; lack of public and media awareness of the harmful effects of tobacco use; tactics of the tobacco industry in hindering 6 Journal of Oncology effective implementation of already adopted legislation or interference in the development of such legislation; lack of or insufficient political will or intersectoral cooperation in tobacco control [69]. Tobacco control policies implemented in high-income countries may not necessarily have a similar effect in low- and middle-income countries, and public health officials should consider this possibility when planning appropriate interventions [70]. In summary, the definitive results in public health improvement will depend on how aggressive a particular government is on implementing the elements of the WHO’s FCTC. 7. Clinician and Academic Institution-Based Initiatives Many of the cancers that pose the greatest threat to developing countries are directly linked to tobacco use. In developed countries, most patients have access to a full range of healthcare resources, including smoking cessation programs, but this is not the case in the developing world. In the developing world, primary care physicians and health workers will need to be more involved in cancer control through health promotion programs that emphasize the hazards of tobacco use and prioritize tobacco cessation. Moreover, many low- and middle-income countries will likely see greater increases in quality-adjusted life years (QALYs) through implementation of smoking cessation interventions, tax policies, bans of promotion and adver- tisement, and adoption of smoke-free laws, mainly because tobacco-related cancers are preventable, and specialty cancer care is often limited in these countries [15]. The role of the health professionals is critical in tobacco control. At the local level, brief clinical interventions should be implemented based on patient’s willingness to quit. Strategies should be implemented to advise patients to quit, to reinforce their decision to quit, and identify those who are at risk for relapse to smoking, providing such individuals with counseling, pharmacotherapy, or both [71]. Unfortunately, in many countries, the prevalence of health professional smokers is similar to that of the general population. To set an example, health professionals should be urged to stop smoking [72]. Thus, the eradication of tobacco should become a priority for not only governments, but also medical schools and physicians. Multiple studies have shown that there are differences in patient approach, assistance [73], and educational role between smoking versus nonsmoking physicians [74]. Smok- ing physicians benefit from practical assistance in quitting themselves and providing support to their patients [75]. In 2008, the U.S. Department of Health and Human Services launched a Clinical Practice Guideline, which summarizes the most updated recommendations in clinical treatments for tobacco dependence based on systematic review of evidence-based research that should be implemented by every physician [64]. Along the effective strategies available, clinicians also must be committed to follow a code of professional ethics regarding tobacco. Those should include (1) physicians not smoking, (2) make tobacco cessation assistance a routine part of oncology care, (3) establish all medical facilities to be 100% smoke-free, (4) teaching physicians should lead their students to never become smokers and train them in the prin- ciples of smoking cessation, (5) reject any involvement of the tobacco industry in financing research, training programs, or treatment services for patients, Several international societies have trained medical and surgical oncologists as part of their effort to address the bur- den of cancer in developing countries. Available educational resources for clinicians in developing countries include the European School of Oncology (ESO), the International Cam- paign for the Establishment and Development of Oncology Centres (ICEDOC), the Global Core Curriculum in Clinical Oncology developed by the European Society for Medical Oncology (ESMO), and the American Society for Clinical Oncology (ASCO), among several others [76, 77]. Unfortunately, some academic institutions have received funds from the tobacco industry to support biomedical research. Universities and researchers must understand the motivation underlying such offers of support. By legitimizing the tobacco industry, universities risk their integrity, values, and public trust [78]. Academic institutions should therefore reject offers of funding from the tobacco industry. 8. Conclusion The reduction of cancer-related morbidity and mortality in developing countries should now become an urgent global priority. 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Brandt, A Not-So-Slippery Slope, American Association of University Professors, 2010. http://www.reportingproject.net/underground/ http://www.reportingproject.net/underground/ http://www.globalsmokefreepartnership.org/ http://www.globalsmokefreepartnership.org/ http://www.tobaccolabels.ca/ http://www.tobaccolabels.ca/ Introduction Tobacco-Associated Cancers The Global Problem Tobacco Industry The Growing Problem inthe Developing World Global Approaches to an Escalating Cancer Burden Clinician and AcademicInstitution-Based Initiatives Conclusion References work_4cdcrpwiqvbudkrna2nonphsbu ---- Nature vol 138-n3493.indd © 1936 Nature Publishing Group 608 NATURE OCTOBER 10, 1936 Dr. P. Eggleton's paper dealt with some aspects of this very difficult subject. If a dead muscle is suspended in Ringer's solu- tion, dissolved substances can diffuse freely into the whole of the water of the tissue. When the muscle is alive, most electrolytes can diffuse into one third only of the water it contains ; the remaining two thirds are inaccessible to them. Glucose also has access to one third only, but urea can diffuse freely throughout. Histidine can diffuse throughout, but not its derivative carnosine. It is impossible at present to understand the partitioning mechanism underlying these facts, but some mechanism there must be. The electrical potentials that are developed at cell surfaces are generally believed to be due to unequal concentrations of electrolytes on the two sides. The frog's skin develops such a potential between its two surfaces, but only so long as oxidative chemical reactions are going on, pre- sumably to provide energy for maintaining a con- centration gradient. Mr. 0. Ga.tty has found that specific types of chemical reaction are necessary for this purpose, and is endeavouring to work out their course in detail. Mr. J. S. Mitchell's experiments have been con- cerned with a rather special problem, the chemical changes in proteins brought about by ultra-violet light ; but the method used is one of very general interest and great importance. It is to study the process in monomolecular films spread on a water surface. In such films the molecules can be definitely orientated and molecular structures and transformations may be studied directly. Many important cell constituents and other substances of biological interest can form monomolecular films, so that this very powerful method can be applied to them. A. D. R. Obituary Dr. J. B. Charcot T HE wreck of the polar yacht Pourquoi Pas 'I in a furious gale on the coast of Iceland on September 16, with the loss of all on board but one, was a tragic but not an inglorious end to a famous ship and to the life of the brilliant explorer whose career was so closely bound up with her for nearly thirty years. Jean Baptiste Charcot was born in 1867, the son of a famous physician and neurologist, Prof. J. M. Charcot. He studied medicine in Paris and was for a time an assistant in the Pasteur Institute. Although he published several papers on medical subjects which were not without merit, circumstances deter- mined that his reputation was to rest not on his professional achievements but on the outcome of his devotion to the sport of yachting. Charcot's love of the sea brought him under the influence of the revival of polar exploration at the beginning of the present century and fired him to take a part. He raised funds for the purchase and equipment of a small ship, renamed the Franr;ais, for an arctic voyage, but changed the scene of his exploration to the Antarctic and sailed in 1903 with the intention of searching for the missing expedition of Otto Nordenskjold in the Weddell Sea. When in South America he heard of Nordenskjold's relief, and took the Franr;ais to the west side of Graham Land, there to continue the work begun by Gerlacbe in the Belgica. He reported the existence of Loubet Land south of Graham Land, and pushed on within sight of Alexander I Land ; but the main value of the expedition lay in the physical observations and natural history collections made with the aid of his efficient scientific staff during two years. On his return, Charcot secured Government support for a second expedition, and after a close study of the British, German and Norwegian polar ships, he had the Pourquoi Pas? designed to unite the best features of them all. In her he cruised for two years, 1908-10, to the west and south of Graham Land, giving precision to the somewhat nebulous lands seen from the Franr;ais. He explored the coast of a large island south of the Antarctic Circle to which be gave the name of Adelaide Island, believing it to be an ex- tension of the small island so named by Biscoe in 1832. South of Adelaide Island he discovered a large inlet which he named Marguerite Bay and a new land south of Alexander I Land to which he gave the name of his father. These lands he could not approach, and he believed them to be islands lying off the Antarctic continent. As on the previous expedition, the main value of the researches on the Pourquoi Pas ? came from the very extensive series of magnetic, meteorological and oceanographical observations and the collections of geological and zoological specimens. After completing the publication of his results, Charcot continued to make oceanographical summer cruises in the Pourquoi Pas?, especially in the Green· land Sea and along the west of Scotland. He was one of the very small number of sailors to effect a landing on the remote islet of Rockall, 185 miles west of St. Kilda, and he acquired an intimate know- ledge of the complex coMts of the Outer Hebrides. At the beginning of the Great War his Government insisted on placing him in the Army medical service, but he succeeded in proving that he was a better sailor than a surgeon, and received a commission in the French Navy. Later he was given command of © 1936 Nature Publishing Group OCTOBER 10, 1936 NATURE 609 a British vessel with a combined French and British crew, and in her he rendered valuable service by preventing the establishment of enemy submarine bases in the desolate harbours of the west of Scotland which he knew so well. After the War, Charcot continued to visit East Greenland on summer training cruises with young French sailors. He made a trip to Scoresby Sound in 1931 to select a site for the French station for the Polar Year observations of 1932-33, and afterwards transported the party of French physicists to and from the Sound. He rendered willing and efficient help to many of the recent Greenland expeditions. To young explorers Charcot was always a generous friend and a wise counsellor, and he gave the full benefit of his experience to Mr. Rymill of the British Graham Land expedition which is now in the field. Charcot was a man of great personal charm and high culture. His literary style was clear and graceful, and his speeches on his many visits to England Wl'lre always bright and to the point, for he had a perfect command of the English language and a gift for making enduring friendships. Apart from his scientific writings and his polar narratives, he was the author of a very attractive book on Christopher Columbus in which historical critics recognized the value of the interpretation of Columbus's voyages by a scientific man with a practical knowledge of seafaring. Charcot's genius won for him full recognition as a leading man of science both at home and abroad. He was a member of the Institut de France and of the Academies of Sciences and Marine, received the gold medals and honorary membership of all the chief geographical societies of the world, and at the time of his death was president of the Paris Geographical Society. HuGH RoBERT MILL. Dr. A. Anderson DR . .ALEXANDER ANDERSON, whose death at the age of seventy-eight years occurred on September 5, was a physicist and mathematician of note. He was professor of experimental and mathematical physics at University College, Galway, for almost fifty years. He was one of the last holders of the joint chairs of experimental and mathematical physics, a distinction shared with Prof. Morton of Belfast, who paid a graceful tribute to him in The Times of September 10. Dr. Anderson was born in 1858. He studied in Queen's College, Galway (as it was then called), and graduated in 1880. He won an entrance scholarship to Sidney Sussex College, Cambridge, in 1881. He was sixth wrangler in 1884. After a short period in the Cavendish Laboratory under Sir J. J. Thomson, he was appointed professor at Galway in 1885. He became president there in 1899 and held both offices until his resignation in 1934. Anderson is perhaps best known for his method of measuring self-inductance, which is in general use in laboratories of physics and electrical engineering. Two other of his methods have become standard practice, namely, his method of mea.'luring surface tension and his method of measuring the viscosity of a gas. From 1890 onwards he published many papers in experimental and mathem11.tical physics on optics, electrostatics, electromagnetics and relativity. Of his researches in experimental physics, possibly the most important is his contribution to the theory of contact differences of potentiaL In mathematical physics his papers mainly deal with new methods of approach to older theory. The remarkable thing about Anderson was his really wide knowledge of experimental and mathe- matical physics and his continuous keenness as a teacher, especially of advanced students. I remember hearing the late Prof. McClelland, his most dis- tinguished student, state many years ago that it was usual for his advanced lectures on mathematical physics to go on continuously for three hours, and this was his practice almost up to his retirement. He simply revelled in physical and mathematical problems. Personally Dr. Anderson was a most kindly man with a marked sense of humour. M. P. Prof. Antoine Meillet WE regret to record the death of M. Antoine Maillet, professor of philology at the College de France, and president of the Historical and Philo- logical Faculties at the Ecole des Hautes Etudes, Paris, which took place at Chateaumeillant (Cher) on September 22, at the age of seventy years. Prof. Meillet was born at Moulins (Allier) on November 11, 1866. He became a lecturer in the Ecole des Hautes Etudes in 1891. From 1904 until 1906 he was a professor of the Ecole des Langues Orientales Vivantes and in the latter year was appointed to the chair of comparative philology in the Ecole de France. M. Maillet was regarded as one of the most eminent philologists of the day, his researches ex- tending over the whole field of the Indo-European and Iranian languages. His "Introduction a !'Etude Comparative des Langues Europeennes", first pub- lished in 1897, has been through many editions, the last appearing in 1934. WE regret to announce the following deaths : Prof. Henry Le Chatelier, For. Mem. R.S., and honorary fellow of the Chemical Society, on September 17, aged eighty-five years. Brig.-General Sir Brodie Haldane Henderson, K.C.M.G., C.B., president in 1928-29 of the Institution of Civil Engineers, who designed the Lower Zambezi Bridge, on September 28, aged sixty-seven years. Lieut-Colonel R. Knowles, C.I.E., acting director of the Calcutta School of Tropical Medicine, known for his work on medical protozoology, on August 3, aged fifty-two years. Dr. A. H. Mackenzie, C.S.I., C.I.E., pro-Vice- Chancellor of the Osmania University, Hyderabad, who was a member of the recent Quinquennial Reviewing Committee of the Indian Institute of Science, Bangalore, on September 26, aged fifty-six years. Obituary work_4e6xauvjorcy5o7ytcdwagx3ta ---- RESEARCH Open Access Dialogic meaning construction and emergent reading domains among four young English language learners in second-language reading Deoksoon Kim Correspondence: deoksoonk@usf. edu Foreign Language Education and Second Language Acquisition/ Instructional Technology (SLA/IT), Secondary Education Department, 4202 East Fowler Ave, EDU 105, Tampa, FL 33620, USA Abstract Rapid growth of English language learner populations has challenged teachers, particularly because English language learners’ academic success and second- language literacy are closely linked. Using qualitative research methods and verbal protocols, this study pursued two goals, namely examining English language learners’ meaning-making processes as they engage in reading activities and how they construct meaning within particular contexts. Results document that dialogic responsive reading offers English language learners the zone of meaning construction for apprehending and mastering within and about domains. These English language learners adopted dialogic-responsive reading, relying on five domains: cultural, aesthetic, efferent, dialogic, and critical. These domains offer English language learners an evolving responsive reading strategy to develop second- language literacy. These five domains are interwoven with the cultural knowledge, prior experiences, and performance styles of diverse learners to render the learning process more meaningful and effective. English language learners position themselves centrally, retaining their cultures’ values, experiences, and perspectives while embracing new content and knowledge in the reading process. Keywords: English language learner, Dialogic meaning making, Second-language literacy, Cultural knowledge Background Literacy is crucial to English language learners’ (ELLs’) academic success: It enables them to become active learners and social beings in an English-speaking culture (Cum- mins 1992). The rapid growth of the ELL population over the past decade (Peregoy and Boyle 2008) has demanded teachers’ and administrators’ attention and challenged them pedagogically. As the number of ELLs continues to rise, researchers continue to describe the challenges of learning to read in a first language (L1) and a second lan- guage (L2). ELL refers to learners who are learning English as their second language after learning a first language other than English (Stern 1983). Given the complex pro- cess of L2 reading, exploring L2 reading processes is demanding (Fitzgerald 1995; Koda 2007). Researchers agree that these processes are closely linked to academic suc- cess (August and Shanahan 2006; Cummins 1992). Over the past decade, a convergence of state and federal policies has emphasized and institutionalized the teaching of reading and reading skills and subskills (e.g., phonemic Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 © 2011 Kim; licensee Springer. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. mailto:deoksoonk@usf.edu mailto:deoksoonk@usf.edu http://creativecommons.org/licenses/by/2.0 awareness, phonics, vocabulary; Pacheco 2010). Whereas some reading researchers argue that these skills and subskills are essential aspects of the reading processes (National Institute of Child and Health and Human Development [NICHD] 2000), others have strong concerns about teaching narrow skills-based reading approaches to ELLs (Olson 2007). Furthermore the main trend moves quickly to whole texts, empathizing reading fluency to enhance reading comprehension, whereas a more balanced approach may be more helpful to some students (Alexander and Fox 2004). L2 reading appears to be a more complex process than L1 reading (Fitzgerald 1995): In their report on the National Literacy Panel, August and Shanahan (2006) demon- strated an urgent need to support ELLs ( language-minority students) in their rapid growth. They addressed ELLs’ challenges in reading and writing well in English and indicated that the nation’s K-12 schools, should urgently address the close link between ELLs’ English proficiency and their empowerment and future success. They identified six key elements for ELLs’ literacy development: (1) Key components of read- ing consist of phonemic awareness, phonics, fluency, vocabulary, and text comprehen- sion (NICHD 2000). (2) High-quality instruction in the key components of reading boosts oral proficiency. (3) Oral proficiency and literacy in L1 facilitate literacy devel- opment in English. (4) There are important individual differences in L2 learning (i.e. general language proficiency, age, English oral proficiency, cognitive abilities, previous learning, and the similarities and differences between the first language and English). (5) Due to the challenges, better assessments for ELLs must be developed. (6) Finally, home language experiences have a positive impact on literacy achievement. Initially, however, August and Shanahan (2006) stated that there little evidence of the impact of sociocultural variables in literacy achievement or development based on the panel’s summary. In contrast, Cummins (2009) argued that sociocultural factors are significant in L2 learning in his review of August and Shanahan (2006), and Pray and Jimenez (2009) accepted Cummins’ claim, which interestingly was against the Panel’s recommendation. This important debate lead me to explore the involvement of social factors in L2 literacy and further discuss the uniqueness of ELLs’ L2 reading. It evolves from both the first and second languages and other factors such as linguis- tic differences between L1 and L2, cultural differences, and the particular context. His- torically, the cognitive processes involved in L2 reading have been discussed with various foci. Studies have examined ELLs’ language acquisition (Ellis 2008) and focused on textual components such as L2 vocabulary acquisition, grammatical structures, and the appreciation of L1 linguistic knowledge for L2 reading (Koda 2007; McElvain 2010). Some researchers have also focused on the interrelationship between L1 and L2, such as L1 positive transfer to L2 learning and how L2 reading skills transfer to L2 reading proficiency (Koda 2007; McElvain 2010; Yamashita 2002). Few studies, how- ever, address L2 reading processes and dialogic meaning construction, critical areas for understanding L2 reading processes and vital for providing appropriate pedagogical recommendations. As Freire observed in 1970, ELLs are historical, cultural, social, and political beings, and L2 reading is a sociocultural practice (Perez 1998). L2 reading pro- cesses for English, however, have not yet been fully discussed and there is an urgent need to discuss ELLs’ L2 reading processes in situated contexts (boundaries of dialogue in social contexts according to Bakhtin 1986). From a sociocultural perspective, reading is a vital system for communication and interaction (Perez 1998). Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 2 of 21 The definition of literacy has evolved to encompass the entire process of thinking and meaning-making (Goodman 1987), which is how readers make sense of texts. Au (1993) extended the definition of literacy from mere reading and writing to include “the ability and the willingness to use reading and writing to construct meaning from printed text, in ways which meet the requirements of a particular social context” (p. 20). She emphasized the importance of the readers’ willingness or feelings about read- ing and writing on the process, suggesting the reader plays a central role in the con- struction of meaning. Goodman (1987) defined L1 reading traditionally as “meaning construction.” Morti- mer and Scott (2003) described the meaning-making process (interchangeable with meaning construction in this paper) as “dialogic in nature as the students try to make sense of what is being said by laying down a set of their ‘own answering words’ to the words of the teacher” (p. 122). Based on Dewey’s (1933) philosophy, Krauss (2005) observed, “human beings have a natural inclination to understand and make meaning out of their lives and experiences” (p. 762), and reading (meaning making) occurs in “dialogic” ways (Bakhtin 1986). Reading is the purposeful construction of meaning within or about the situated context called dialogue (Bakhtin 1986), also known as communication or a semiotic exchange (Gee 2008). Johnson (2004) stressed that L2 learning can be explored socioculturally when the dialogic perspective of L2 reading is emphasized. Furthermore, the U.S. “National Reading Panel Report: Teaching Children to Read” suggested effective reading instruction for children. Particularly, this document recom- mended the importance not only of practicing reading aloud, but also of teaching stra- tegies to improve reading comprehension (International Reading Association 2002). The report’s summary highlighted the effective instructional strategies of vocabulary and text comprehension (International Reading Association 2006). This study investigated the L2 reading processes of four elementary ELLs, focusing on the interactions between the learners and various texts in situated contexts. Using qualitative and verbal protocols, I sought to elicit and examine ELLs’ meaning-making processes. This study pursued two goals: the examination of (a) ELLs’ meaning-making processes as they engage in reading activities focusing on learner’s internal cognitive reading process and (b) how they construct meaning within the particular contexts (including such social factors as cultural background, personal experience, L1 and L2 literacy skills, and oral language proficiency). To answer these questions, I reviewed the available contemporary literature on L2 reading, including the cognitive and social aspects of L2 reading. Next, I expanded the discussion to include the dialogic reading process. L2 Reading Research ELLs have various L2 proficiencies, cultural orientations, and cognitions, all closely related to age differences (Koda 2007; Stern 1983). Koda (2007) documented three major components of reading: (a) decoding (extracting linguistic information directly from print); (b) text-information building (integrating the extracted information into written form); and (c) reader-model construction (synthesizing the incorporated text information with prior knowledge p. 4). L2 reading obviously involves two languages. According to McElvain (2010), linguistic knowledge and prior knowledge help ELLs to Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 3 of 21 construct meaning while engaging in reading events. ELLs’ language proficiency (Koda 2007) and their L1 skills are directly linked to their L2 reading abilities (McElvain 2010). Cummins’ (1992) exploration of the cross-linguistic relationship in reading skills demonstrated that L2 reading success depends primarily on L1 literacy competence. Related studies discussed the relationships between L1 literacy skills and L2 reading (McElvain 2010), L2 language proficiency and L2 reading (Koda 2007; Yamashita 2002), and L1 literacy skill and L2 proficiency’s influence on L2 reading (Nassaji 2007). Likewise, prior learning experiences can be considered a reservoir of knowledge, skills, and abilities to be employed when learning a language and literacy skills (Koda 2007; McElvain 2010). L2 reading is the product of word decoding, vocabulary knowledge, grammatical skills, and oral text comprehension (McElvain 2010). L2 proficiency with vocabulary and grammatical skills, however, appears closely linked to reading fluency and compre- hension (McElvain 2010). Koda (2007) discussed the role of linguistic knowledge in text-information building, emphasizing syntactic awareness and text-structure knowl- edge. Word-recognition and decoding-skill studies showed that these skills cannot cover the full process of reading (Avalos 2003). Researchers have documented contemporary L2 reading theory and reading strate- gies, but have not yet focused on the dialogic responsive reading process. Johnson (2004) emphasized that dialogic responsive reading is comparable to the sociocultural perspective in L2 learning. ELLs are at the centre of meaning construction, struggling to make meaning out of strange and foreign words, and their dialogic meaning con- struction must be closely observed and addressed. Dialogic Responsive Reading Dialogue is described as a, “give-and-take exchange of language between two indivi- duals” (Uebel 2007, p. 331). Bakhtin (1986) saw the individual utterances in a dialogue as the junction between a speaker’s specific speech intent and the listener’s responsive- ness; these two elements are constant and stable and create original meaningful lin- kages within the given boundaries. These two entities, speaker and active listener, create the true essence of meaning through purposeful exchanges. Bakhtin (1986) described dialogue as “The life of the text ... always develops on the boundary between two consciousnesses, two subjects” (p. 107), the author and the reader. Reading is an utterance within the given boundary, a kind of literacy work (Bakhtin 1986). The boundary can be a “rejoinder, letters, diaries, inner speech, and so forth” (p. 115). Bakhtin referred to reading as “an utterance” that creates brand new innovative mean- ings, claiming that the possibilities in the written word are utterly boundless. The ELL who reads is as important as the author and is always central to meaning making, either obtaining knowledge, connecting to culture, engaging in lived-through experience (Rosenblatt 1978) reaching that deeper level of connection that generates readers’ reading pleasure, dialoguing, or creating entirely new meanings from the read- ing (Bakhtin 1986; Freire 1970). Within the L2-reading focus, responsive reading has been referred to under various names, for example, (Rosenblatt’s 1978; 1986) efferent and aesthetic reading; Perez’s (1998) literacy as a cultural practice, which means literacy makes sense within the given context; Bakhtin’s (1986) reading as a dialogue; and Paulo Freire’s (1970) critical Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 4 of 21 literacy. These responsive readings demonstrate different foci of meaning making, but all represent a dialogue between the reader and the text in the situated context. Rosenblatt’s (1978) reader-response theory sees the reader as either gaining a lived- through experience (interchangeably aesthetic) or obtaining information from the text (interchangeably efferent), which is how the ELL creates a dialogic relationship with the text. This relation could be efferent (informative) or aesthetic–transactions occur- ring with the text through the reader’s lived experience, based on the reader’s engage- ment with the text, which will reflect the reader’s level of direct attention. Our individual experience is the sum of these transactions, and the continuous processing of these transactions is the ever-increasing enlargement of experience. Dialogue, an invitation to think and produce meaning, is frequently referred to as dialogic thinking (Bakhtin 1986; Wells 2007). Dialogic thinking goes well beyond two people talking, essentially including any form of two-way semantic interchange between speakers, building a mosaic of new meaning among various texts (Hartman 1995), as well as between readers and texts (Rosenblatt 1978). When literacy is viewed as culturally and politically embedded cross-cultural communication (Freire 1970), the ELLs’ cultural and political contexts become inseparable from utterances, content, style, and arrangement (Bakhtin 1986). ELLs’ cultural and political contexts may differ from those of the text. L2 reading is also “a set of cultural practices and a product of cultural activity” (Perez 1998, p. 252). ELLs identify with words based on their under- standing of the texts (Koda 2007), relying on their historical, cultural, and social back- grounds to understand the words. Creative and critical thinking (Freire 2000) helps language learners develop aware- ness of others and value and appreciate differences. Such thinking also fosters con- structive analytical skills, sensitivity to others, cultural and critical awareness of the self and others, and an evolving worldview (Freire 1970). L2 reading praxis, reflective and active meaning creation through reading texts (Freire 2000), engages learners in learning language and in reading, analysing events and situations from various perspectives to understand how these perspectives position readers in the world. In this instance, reading is a core force of literacy and active learning; reading becomes a basic medium for evoking one’s power in life (Freire 1970, 2000). Freire (2000) pointed to the re-creator concept of reading through the dialogic relationship between the author and reader: The ELL who reads becomes a rewriter, composing a new story while making meaning within the author’s authority. L2 read- ing entails a critical perception of the world and the transformation of the world through practical action and reflection (Freire 2000). While reading, ELLs act as both reader and writer to create comprehension (Bakhtin 1986; Freire 2000). These theories all clearly demonstrate the degree of dialogue and interrelationship among the reader, the text, and the context. Reading is a dialogic responsive process of meaning construction, with the reader responding to the text by creating a unique transactional moment in a particular time and space, the situated context (Rosenblatt 1978). All reading processes are closely linked to the boundary of dialogue and to the vital essence of dialogue. ELLs construct meaning by creating dialoguing with their past experiences and social interactions with others (Windschitl 2000). Learning to read and write are constituted as acts of knowing, reflected as values, or situated as discourse within a given cultural and social context (Gee 1996; Perez 1998). When Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 5 of 21 considered as a dialogue focusing on the reflective process and meaning production, reading becomes a powerful, essential method of transformation whenever the reader encounters a new concept or constructs meaning from the word. Dialogic reading occurs in situated contexts in suitable domains. Domains as Peripheries of Situated Meaning Dialogue or reading requires a “boundary” with the text to make sense of it in a situ- ated context (Bakhtin 1986; Gee 2008). Language and reading have particular meanings in any particular context (Rosenblatt 1978), a concept very similar to Gee’s (2008) ideas on domains. Gee defined authentic learning in a domain as learning that “leads to growing mastery of the semiotic domain’s design grammar and growing member- ship in its associated affinity group” (p. 139). For Gee (2008), design grammar is a set of principles or patterns that legitimate materials in the domain. The domain situates authentic learning (Lave and Wenger 1991), which is situated meaning (Perez 1998), as learners make sense of semiotic domains within the given contexts. Thus, within a domain, multimodalities (i.e., words, symbols) have meanings and combine together (Gee 2008). Gee also emphasized that learning is a trajectory for developing mastery status in the semiotic domains. By learning semiotic domains, learners can associate certain rules and content with affinity groups–groups of people associated within a semiotic domain. These individuals share a community of practices, a set of common goals, and subscribe to common values and norms (Lave and Wenger 1991). Methods This fifteen-month qualitative research involved four second- and third-grade ELLs in the same classroom at an middle-class, urban public elementary school in the south- western United States. As a participant observer (Merriam 1998), I examined how ELLs constructed meaning. Using qualitative research (Lincoln and Guba 1985) as a general method, I inductively analysed the verbal protocol tasks and the interview data. Verbal protocols captured the moments when thinking processes occurred (Ericsson and Simon 1993; Pressley and Afflerbach 1995). The main question of the protocols was based on a fundamental question–"What’s on your mind?"–while the students were reading stories. Verbal protocols include think aloud (verbalized concurrently), introspection (verbalized with explanations of the readers’ thoughts) and retrospection (verbalized immediately after the task; Ericsson and Simon 1993). Verbal protocols provide a window into ELLs’ thinking process. The modified research method for this study sought a verbal report, but sought it in a method focused on comfort, a safe set- ting, in an open, friendly atmosphere for the young readers to vocalize their thoughts, minimizing any discrepancies between the ELLs’ thinking process, vocalization, and language ability. The study’s verbal protocols consisted of think-aloud and retrospec- tive protocols. Setting and Nature of the Instruction Two language arts/literature classes provided the social context for this study: Ms. Green’s language-arts and literature classroom for 10 months and Ms. Lopez’s class- room for 5 months (all names are pseudonyms). Both were certified ESOL teachers and promoted interaction among students using small-group activities. Ms. Green, Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 6 of 21 monolingual, always with a smile, promoted collaborative learning and scaffolding, encouraging students to work in groups and to help one another with questions. Her classroom was equipped with bilingual texts, dictionaries, and other hands-on materials for ELLs. Ms. Lopez, bilingual (Spanish and English), promoted bilingualism and var- ious approaches and learning, while clearly recognizing that ELLs have many strengths. For example, her classroom had many Spanish vocabulary cards on its walls. Participants Using purposive sampling (Merriam 1998), I selected four second-grade ELLs, Hiroki, Jaewon, Maria, and Evert as participants for this study. The four ELLs had different first languages and cultures and had been learning English for under three years. These four ELLs lived near their school in lower-middle-class neighbourhoods. Hiroki, a seven-year-old Japanese American, identified his main hobby as “doing chess.” Ms. Green told me that Hiroki was an excellent problem solver and excited about creating new ideas. Hiroki spoke Japanese at home and had eighteen months of English experience, giving him an intermediate command of English. He was learning Kanji through a correspondence course at home with his mother. Jaewon, a seven-year-old Korean American, was an exemplary second grader with a positive attitude toward his teacher, his peers, and his class. Though born in the Uni- ted States, Jaewon spoke Korean fluently at home, so English was his L2 with three years of English education. His home environment contained various Korean books, songs, and decorations depicting “little Korea.” When I tried to speak with his mother in English, she was not able to respond to me. Her English proficiency was that of a total beginner. I only spoke with her in Korean, and, throughout her interview, she expressed her concern about her poor English proficiency affecting Jaewon’s academic progress. Maria, an eight-year-old Mexican American, learned Spanish as her first lan- guage. She had lived in the United States for 10 months when my research began. Flu- ent in Spanish, she was a beginner in English. Maria’s mother was a competent bilingual who was born in the U.S. and came to Mexico at her age of 18. She had lived for 16 years in Mexico. Maria’s mother reported that L1 knowledge supported her learning English as an L2, as Maria understood how to use language and language structures (Bigelow and Tarone 2004). She spoke Spanish at home and often used Spanish while reading stories and when she became excited. Evert, a nine-year-old Swede, had come to the United States with his family just one week before I met him. A third grader in his school, Evert joined this second-grade classroom for the language arts and literature as a pull-out because the teachers were ESOL-certified. He was a total beginner in English. With his advanced L1 literacy skills, Evert’s L2 English developed remarkably swiftly. In four months, he was able to read a first-grade book with only minor help. I assessed each ELL’s English proficiency based on the teacher’s evaluations, their standard test scores (school diagnostic report, STAR reading, APS word-recognition placement inventory), various documents (spelling tests, math tests, quarterly tests, reading scores), and my own observations. I also assessed their L1 proficiency based on their parents’ evaluations and my own 15 months of observations. L2 reading profi- ciency was measured by spelling tests and the school diagnostic report. Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 7 of 21 Materials The materials included culturally related and culturally unrelated content; I chose the selections for each ELL relative to his or her specific L1 cultural orientation, cognition, level of task, reading level, and English proficiency based on Bishop’s (1993) cultural- relevance guidelines. The stories I defined as culturally related included the ELL’s cul- tural concepts, ethnicity, cultural heritage, L1, events, and experiences. Although each ELL used various texts, this study’s focus was not the ELLs’ reading performance or on comparing the children’s reading abilities. Rather, this study explored the children’s dialogic responsive meaning construction. The culturally related stories included Passage to Freedom for Hiroki, Woodcutter and Tiger Brother for Jaewon, I Hate English (related because the story involves com- ing to the United States) for Evert and Maria, Pettson and Findus for Evert, and Family Pictures for Maria. The culturally unrelated material included two depictions of Chris- topher Columbus (Follow the Dream and Encounter) and Hiroko Makes the Team for Hiroki and Jaewon, and Wilfrid Gordon McDonald Partridge for Evert and Maria. Per- sonal experience, such as arrival in the United States, was classified as culturally related material for the ELLs. Since the ELLs were all from different countries and at various stages of English proficiency, it was not possible to use the same texts; instead, I chose the texts to fit each ELL, based on cultural criteria (Bishop 1993) and consultation with each teacher. Data Collection Multiple case studies and verbal protocols helped ensure the trustworthiness of the study’s findings. I drew upon four sources of data concerning the ELLs’ reading pro- cesses: 1. Observation: As a participant-observer, I visited the participants’ classrooms once or twice a week for three or four hours each visit and collected field notes. 2. Interviews: During the research period, I conducted two interviews with each participant, their parents, and their teachers. Evert’s mother participated as a trans- lator in Evert’s first interview and verbal protocol. After that, Evert was able to par- ticipate in other activities with minimal assistance from his mother. 3. Verbal-protocol reports: Each student conducted three verbal protocols, based on cultural orientation and English proficiency. 4. Documents: I reviewed the ELLs’ classroom documents (reading responses, jour- nals, and test scores). The verbal-protocol sessions were conducted under my guidance. Verbal-protocol sessions included one training session and three protocols held in the classroom and home settings. The prompts provided after each session followed the retrospective-pro- tocol guidelines. The prompts consisted of questions related to meaning construction ("Can you retell the story?”) and dialogue and interaction between the story and the reader ("How do you feel after reading the story?”). In a typical think-aloud session, data gathered were the ELLs’ reported immediate responses while reading (Davis and Bistodeau 1993) and their responses to the given prompts. Verbal reports demon- strated how each of these ELLs perceived their thought processes. Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 8 of 21 Data Analysis A systematic and rigorous analysis of the data followed a qualitative case-study data analysis. The twelve verbal reports were tape-recorded, transcribed, and analysed fol- lowing the qualitative research analysis method (Lincoln and Guba 1985). Based on Creswell’s (1998) data-analysis spiral, my analysis involved four stages: data manage- ment, reading and memorizing, describing and classifying, and representing and visua- lizing. In data management, I organized files and units of verbal reports manually, using index cards including protocol title, ELL’s name, etc. Then I started making sense of the data, reflecting and writing notes. I read and reread the data, carefully coding it. After coding the data, I constructed categories while linking codes (e.g., cul- turally related, obtaining information; Corbin and Strauss 2007). While categorizing codes and discovering themes, I also reflected on my research questions in relation to the main focus of study–dialogic responsive reading. Themes and categories emerged inductively from the data. For description and classification, I described the context, classifying and interpreting data using comparison. Finally, I visualized and represented the newly evolved themes (e.g., similar responses to culturally relevant texts: Maria and Evert responses after reading I Hate English). I also compared and contrasted the four participants’ findings for the two beginners (Maria and Evert) and the intermediate and fluent ELLs (Jaewon and Hiroki). I also analysed other qualitative data, including transcribed interview data, observation notes, and reflective journals using the same procedure. To ensure the trustworthiness of the study, I confirmed the answers with participants throughout the study. I also carried out peer debriefing and maintained a reflective journal (Lincoln and Guba 1985). Qualitative research is limited to specific cases and contexts. Participants’ emic voices and thick descriptions from the cases, however, pro- vided a detailed, rich account of the study’s observations and insights (Lincoln & Guba, 1985). Multiple data sets and analyses allowed triangulation to enhance trust- worthiness and will allow the transfer of this study into various contexts of teaching and learning. Results As I focused on ELLs’ meaning construction, several themes emerged from the data: (a) ELLs’ cultural perspective; (b) ELLs’ lived-through experiences; (c) ELLs’ efferent reading; (d) ELLs’ dialogic meaning construction; and (e) ELLs’ critical reading to learn. To understand how ELLs make meaning while reading stories, it is vital to understand when, why, and how they work within or about these various domains. ELLs’ Cultural Perspective Each ELL had a different first language, a different level of English proficiency, a differ- ent cultural background, and different prior knowledge–all reflected in their rich and diverse course-reading processes. The cultural perspective is derived from Lederach’s (1995) definition of culture: “Culture is the shared knowledge and schemes created by a set of people for perceiving, interpreting, expressing, and responding to the social realities around them” (p. 9). Maria’s case most clearly represented how beginner ELLs link their new learning to cultural knowledge and prior cultural experiences. Her cul- tural knowledge motivated her to read Family Pictures (Protocol 11). She identified Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 9 of 21 closely with her culture and cultural experiences while reading Family Pictures, exem- plifying how beginner ELLs refer to themselves while making meaning. While reading the “Birthday” chapter in Family Pictures, Maria spontaneously spoke and sang in Spanish: They put you a little thing and they turn you around three times and they sing a little song that’s kind of, ‘Dale, dale, dale, pégale asina, porque si no le das pierdes el camino.’ It’s like ‘hit it, hit it.’ It’s kind of hard to translate it. (Protocol 11) Maria’s cultural experiences motivated her to engage in this culturally related literacy event. Singing a song about the piñata, Maria evinced a high degree of transaction with these stories, and the transactional moment enriched her emotional connection to her father (in Mexico), saying “I missed him” with tears in her eyes. Her prior experi- ences gave her an emotional connection to the piece, helping her build context with her reading. All ELLs were very responsive in their reading when the contents are cul- turally related to them. ELLs’ Lived-Through Experiences As beginning learners, Maria and Evert’s cases revealed their lived-through experiences while reading I Hate English. Lived-through experience, derived from Rosenblatt’s “aes- thetic” reading, is related to how ELLs experienced their reading as a way of obtaining their pleasure. Thus, ELLs found “transactional” moment, which seems themselves in the story while reading (Rosenblatt, 1978). This aesthetic stance of reading enabled the ELLs to speak with strong voices. For example, Maria identified deeply with Mei Mei in I Hate English: Because it’s from another place. Hong Kong is another place from New York, so she wants to speak Chinese, and they want her to speak English, so she [Mei Mei] came here and [she] doesn’t want to speak English, only wants to speak Chinese. (Protocol 10) Maria used her personal opinions, culture, and experiences to identify the story’s main ideas and to determine what was important in the text. She identified with Mei Mei’s resistance to learning English and compared it to her own situation. Placing her- self in Mei Mei’s situation, Maria agreed with Mei Mei: “No. Mei Mei doesn’t speak English because she wants to speak Chinese. But everybody is bugging her because they want her to speak English. And she wishes she was in Hong Kong” (Protocol 10). Maria understood why Mei Mei did not want to speak English: “Because it’s not her main language.” Evert also dialogically connected to himself, using his L1 literacy skills, asking ques- tions and monitoring his comprehension while reading I Hate English and Pettson and Findus. His most used skills were his connection to self and rhetorical strategies, which transferred well from his L1 (Bigelow and Tarone 2004). Like Maria, Evert also identified with Mei Mei’s struggles, and frustration. He stated, “Yeah, I know how she feels. I felt the same thing as her when I came to a new country” (Protocol 6). Dialo- guing with Mei Mei, Evert became part of the story with her, connecting his cultural Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 10 of 21 experiences to hers. Evert understood Mei Mei’s situation through his own situation, by reflecting on his lived experience (Rosenblatt 1978). He also recommended building the community and demonstrated his aesthetic stance by proposing that a friend read the story: “I want to ask a friend to read this book. So they can understand how I feel” (Protocol 6). Evert connected deeply with Mei Mei’s personality and experience as an English beginner in the United States, demonstrating total transaction with Mei Mei through her language struggles and reflecting on his own experience. Having time to under- stand the context with the other (Mei Mei in this instance) was very important for Evert. He felt safer, not so alone, having shared Mei Mei’s experiences through the reading process. Reflecting his engagement, he evaluated the story with “She [the author] has done a good book” (Evert’s interview). Evert clearly believed that sharing this story with his friends would show them his situation in his new country. ELLs’ Efferent Reading The four ELLs developed their vocabularies, syntax, and concepts through reading. For all ELLs, the reading process provides new information and knowledge. For example, Hiroki attained the new word visa in the context of Passage to the Freedom. He under- stood the word as “And he has to, like, sign everybody’s–I don’t know how to read that word [visa]” (Protocol 1). Hiroki did not know how to read the word, but understood a meaning in context: “I kind of figured out. It was, like, this piece of paper that he [ambassador] would sign. Like, the part, like, he signs those pieces of papers that help those other people from, like, getting killed and stuff” (Protocol 1). Hiroki discovered the meaning of the word “visa” from the context of the story. Maria tried to grasp the main ideas, as well as the main words of the stories by using simple words such as the race, Chinese and Hong Kong, and fair and piñata to point out the main ideas and significance of the story. Evert identified a memory as “Some- thing very sad or something happy,” adding his own perspective after reading Wilfrid Gordon McDonald Partridge (Protocol 12). Defining complicated or key words (e.g., memory) appeared to be an important step in obtaining new information. Evert said he knew the word “memory” in Swedish, so he comprehended the word in English without any effort. Similarly, the learners derived lessons from the stories. For example, after reading Hiroko Makes the Team, Jaewon observed, “The important part is, be nice to each other–Never make fun of other people when they couldn’t. You just need a lot of prac- tice [to win swimming race.] That’s all” (Protocol 3). As they reflected on the stories, new ideas emerged. Hiroki identified the main ideas, figured out the significance of the story, and related the text to his own beliefs. Hiroki’s schema from the content and format of the text was clear. Hiroki also obtained new information by identifying main ideas such as “Friendship” in Encounter (Protocol 5), “I think when the dad [ambassa- dor] starts to help people” in Passage to Freedom (Protocol 1), and “So you can read maps to go somewhere” in Follow the Dream (Protocol 8). ELLs’ Dialogic Meaning Construction ELLs constructed meaning as they read. Jaewon’s case is a good example of this dialo- gic reading process. I observed his strong links to personal preferences, experiences, Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 11 of 21 intertextuality, and cultural orientation (Hartman 1995). Jaewon’s intertextuality devel- oped a mosaic of the text, using his cultural background knowledge, textual knowledge, and world knowledge. His inferential skills also supported using his cognition and knowledge processing while reading, invoking his dialogic thinking experiences. Jaewon often summarized and synthesized the story to evoke dialogic responses and to centre himself in the reading event. For example, Jaewon used O for positive and × for negative to evaluate the story: “This [Encounter] might be also O or X, and this one [Follow the Dream] would be O ‘cause this has landing information, and this just has traveling information, and it’s just different.” He continued, “Like moving, so if you combine these two books [Encounter and Follow the Dream] together, like this [show- ing me the two books overlapped], they would know that it’s Christopher” (Protocol 9). As a synthesizer, Jaewon addressed Columbus’s identity by combining both perspec- tives (Encounter was based on the Native American perspective while Follow the Dream was based on a European perspective). These verbal reports exhibited Jaewon’s dialogic response to the two conflicting characterizations of Christopher Columbus. Jaewon continually created critical points of view based on his theory building, socio- cultural values, and prior knowledge. He dialogued with texts and became a rewriter when reading stories, creating new viewpoints on the story following the author’s spirit. For example, Jaewon represented the two authors’ intentions and purposes after reading the two versions of the Christopher Columbus story by stating, “These are dif- ferent! Are they same? No!” (Protocol 4). ELLs’ Critical Reading to Learn To construct meaning from reading through a critical lens, Hiroki and Jaewon were constantly questioning and evaluating the stories. Hiroki frequently identified impor- tant ideas, determining significance and evaluating the content of the stories. Having determined the important ideas, Hiroki admired Columbus’s adventurous personality while reading the European perspective on Columbus in Follow the Dream: I thought that he was pretty brave to go see–to go around the world. To the other side of–This book [Follow the Dream] is more informative and this more data or– this [Encounter] is part of a different story about this event. (Protocol 8) As examples of Hiroki’s explorations, these two different perspectives on the same story are particularly valuable. After reading Follow the Dream (Protocol 8) and seeing Columbus as the “hero” who discovered America, Hiroki said, “I learned that [Colum- bus] discovered the–he, like, helped the world, because they all thought that the world was flat and they thought–they didn’t know America.” While reading Encounter (Pro- tocol 5), written from the Native American perspective, however, Hiroki considered the concept of invader. Hiroki’s response shifted to the opposite stance while reading the Native American perspective in Encounter. “Different. [Encounter] doesn’t say any- thing about–Christopher Columbus [depicted as an “explorer” in this story] It doesn’t say the word anywhere. I think [Christopher Columbus] shouldn’t. Not the land, just the [Native] American people” (Protocol 5), expressing his objection to Christopher Columbus’s landing in the Western Hemisphere as an invader. Hiroki stated, “They shouldn’t come to America without [Native American’s] permission” (Protocol 5). Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 12 of 21 Through on-going dialogue, Hiroki discovered the main ideas of the stories and further developed critical thinking skills. He dialogued with himself to understand the two dif- ferent perspectives and developed his own understanding of Columbus. Evaluating the historical event, Hiroki comprehended the story Follow the Dream (Protocol 8) from an efferent domain, and he developed empathy as he read Encounter (Protocol 5). Hir- oki proposed that his friends read both books to know Christopher Columbus thoroughly. Discussion All the findings revealed ELLs’ responsive reading processes and meaning construction. ELLs’ responses to the text were highlighted as particular or multiple domains. It’s vital to understand how domains are relevant to the research context and to the results. Based on the findings from the study, three discussions follow: (a) L2 respon- sive reading domains; (b) L2 meaning construction through emergent domains; and (c) pedagogical implications. L2 Responsive Reading Domains These ELLs identified with the stories closest to their cultural schema, experiences, and social values. They tended to evaluate stories as deeply interwoven into their cultural heri- tage, first language, values, and beliefs. The beginner ELLs, Maria and Evert, favoured cultu- rally related texts, while the intermediate and fluent ELLs, Jaewon and Hiroki, connected to culturally unrelated texts through responsive reading processes (Kim 2009a, b). Maria and Evert seemed to feel safe and empowered while reading stories related to their cultural backgrounds and personal experiences. For example, Maria, a mostly quiet student, sang a song with enthusiasm. Evert appeared to be empowered after having read I Hate English, recommending that his classmates also read the text. “They [classmates] will understand me better.” Domains provide ELLs with precursors to support their learning and to engage in the learning process. L2 dialogic reading responses were connected to the readers themselves and to the texts. Maria and Evert made strong connections with their cul- tural knowledge and experiences, making sense of the text by taking a cultural domain that elicited empathy with the text. They invited friends to read cultural-experience stories (I Hate English), whereas Hiroki and Jaewon promoted Encounter and Follow the Dream. Jaewon and Hiroki, more advanced ELLs, were more connected to both culturally and not culturally related stories. Critical reading also stimulated their thinking skills as a bridge to critical and dialo- gic thinking (Bakhtin 1986; Wells 2007). Jaewon and Hiroki not only understood how they thought and used strategies while reading, but also how they demonstrated their dialogical thinking skills (Bakhtin 1986) with the not culturally related texts. Hiroki and Jaewon’s complex set of cognitive structures clarified information about events and the contents of the story, drawing upon their cultural knowledge and prior experi- ences (Anderson 1994). Jaewon and Hiroki comprehended the story’s content, compar- ing and contrasting their pre-existing knowledge to acquire new information. Further, English proficiency seemed an important means for connecting with not culturally relevant texts: as the readers tried to connect to what they were reading, they found themselves having to become more proficient with English. Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 13 of 21 L2 Responsive Reading Through Emergent Domains Results showed ELLs to be active knowledge builders and critical thinkers. In terms of reading as a form of dialogue, culturally related texts empower ELLs, allowing them to establish strong connections to social values evident in the texts, whereas not culturally related texts offer dynamic discourse and creation through the reading process. Dialogic talk is the key to embedding and expanding these experiences (Rosenblatt 1978). Thus, learning always requires domains in situated contexts. While ELLs make meaning from text within the domains or about domains, the reader actively responds to the text, and these processes motivate ELLs’ meaning construction while reading; this transactional process impacts the readers. The domain provides the zone for learners willing to participate and who have the motivation to engage in extended practice within the domain and who are willing to experience “a way that they take on and grow into a new socially-situated identity, an identity that they can see as a fruitful extension of their core sense of self” (Gee 2008, p 147). Within the domains or about the domains, ELLs retain a “core sense of self,” which means that ELLs transform their sense of their own unique individual traits and history. Their identity reflects their ways of acting, interacting, symbols, and so forth. This event becomes a certain means of understanding, constructing meaning, and dia- loguing with the text (Kim 2011). Based on the results, five domains emerged. ELLs situate themselves in five domains–(a) cultural, (b) lived-through (interchangeably aesthetic), (c) efferent, (d) dia- logic, and (e) critical–to construct meaning and to enhance their experience while engaging in reading activities. Apparently the five major semiotic domains for the responsive reading process discussed here are related to such prior theories as Carrell’s (1988) schema theory, Rosenblatt’s (1978, 1993) reader-response theory, and, especially, Bakhtin’s (1986) dialogue and Freire’s (1970) critical consciousness, because all the domains are grounded in the dialogic principle. The study’s results showed how ELLs master certain reading texts, associate with cultural norms and values by affinity group, and successfully construct meaning within multiple domains. The five domains emerging through the study are: the cultural domain, which ELLs connect to their cultural background knowledge and traditions; the efferent domain, through which ELLs obtain information; the aesthetic domain, in which ELLs transact with the story through emotional associations; the dialogic domain, in which ELLs query and dialogue with the story as readers such as through questions to earlier and later selves and to the author (Bakhtin 1986); and the critical domain, where ELLs think critically and become rewriters of the story as readers (Table 1). These domains can be useful for enhancing educators’ awareness of L2 responsive reading processes. All domains offer ELLs rich dialogic opportunities. These five dialogic domains emerging from the data emphasize the role of the ELL in reading processes. Rosenblatt defines stance as a continuum-private, public, or mixed (Rosenblatt 1986). A stance determines “whether selective attention will focus predo- minantly on the public, lexical aspects of meaning, or whether the focus will broaden to permit attention to the matrix of personal overtones, kinaesthetic states, intellectual or emotional associations” (Rosenblatt 1986, p. 124). Specifically, each domain allows the reader’s selective attention to identify and transact with the text in private, public, or mixed stances. Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 14 of 21 These dialogic responsive domains embrace the stances, which are sometimes com- bined. As previously stated, domains provide a zone for the ELL’s active participation and engagement, ultimately creating situated meanings and gaining a membership in affinity groups. Authentic learning occurs while ELLs simulate the perspectives in order to attain situated meanings of semiotic domains within the context of their reading. Alternatively, the domains may stand alone while reading and focus the reader’s attention. This selective attention and situated meaning determine the results of read- ing comprehension and further develop agency of reading and learning. Gee (2008) pointed out that “each of them is associated with a group of people who have differen- tially mastered the domain, but who share norms, values, and knowledge about what constitutes degrees of mastery in the domain” (p. 138). The reader may work in all five domains simultaneously, or in a particular domain at a particular time, with a particu- lar text, or within certain contexts. Through reading, the reader chooses “a selective attention” which means readers are constantly choosing this particular attention in order to master a set of practices, com- mon goals, endeavours, values, and norms by moment-to-moment transaction with the text (Rosenblatt 1978). Examples from this study are Hiroki’s and Jaewon’s responses while reading the two depictions of Christopher Columbus. To evaluate and synthesize the two stories, both boys primarily used the critical and dialogic domains, or a mix- ture of the two. The four ELLs embedded comprehension, sensations, images, feelings, and emotional and intellectual associations. All readers reflect, interpret, find main ideas and details of stories if necessary, evaluating, questioning, and criticizing by choosing and mixing among various domains. ELLs were interacting with the cultural, efferent, aesthetic, cri- tical, and dialogic domains. Cultural domain A cultural domain offers the reader self-recognition as well as a connection to cultural knowledge, experiences, and beliefs while reading stories. All ELLs embrace the values, experiences, and perspectives of their own cultures and cultural experiences even as they expand into others. The cultural domain facilitates comprehension and transac- tion with the text. Maria and Evert, for example, worked extensively in this domain. After reading the Birthday chapter in Family Pictures, Maria burst into song while Table 1 Emerging Dialogic Reading Domains: Cultural, Efferent, Aesthetic, Critical, and Dialogic Domain Stance Example Cultural Private aspect of meaning Maria’s evocation while reading Family pictures. She sings the song about the piñata. Efferent Public aspect of meaning Hiroki’s and Jaewon are gaining information about Christopher Columbus’s adventure story and Evert’s new vocabulary. Aesthetic Private aspect of meaning Evert’s and Maria’s reading processes while reading I Hate English. Dialogic Private and public aspect of meaning Hiroki’s and Jaewon’s responses while reading Follow the Dream and Encounter: The two different depictions of Christopher Columbus drive from the authors’ different intention. Critical Private and public aspect of meaning Jaewon’s and Hiroki’s exploration of the two versions of Christopher Columbus (Encounter and Follow the Dream). Hiroki said Christopher Columbus should not invade the Native Americans. Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 15 of 21 explaining the piñata, fondly recalling her father who was absent. Maria’s spontaneous singing demonstrated her engagement with the story and her ownership of learning (Cummins 1992). Maria and Evert used their cultural domain while reading I Hate English and further developed the agency of reading. They recommended that their classmates read this text to build their learning community. All ELLs used cultural domain frequently and spontaneously. Beginner ELLs such as Maria and Evert engaged in the reading event and related to the culturally related text effortlessly and with enthusiasm. Efferent domain The efferent domain facilitates obtaining new knowledge and is primarily involved with analysing, abstracting, and accumulating what will be retained after the reading. This domain seemed to relate to L1 reading ability closely to L2 reading (Koda 2007; Yama- shita 2002). For example, Evert, a total beginner, was able to identify the main idea and key words (e.g., memory) of Wilfrid Gordon McDonald using his L1 literacy skill. He already knew the word for “memory” in Swedish. This information helped him to comprehend the story easily. Despite of his low L2 proficiency, he readily identified the genre and plot of the story. All four ELLs sought information within this domain, implicitly acknowledging the power of knowledge, from simple vocabulary to complex information. Aesthetic domain In the aesthetic domain, the reader’s attention is focused primarily on experiencing what is being evoked, the lived-through experience, with private aspects of meaning attended to during the reading (Rosenblatt 1978). This domain is closely associated with emotion, sensation, and feelings. For example, Maria and Evert transposed Mei Mei’s feelings with their own while reading I Hate English. They temporarily became Mei Mei. Dialogic domain Bakhtin (1986) insisted that meaning comes into existence only when two or more voices interact: When the voice of a listener (reader) responds to the voice of a speaker (author). Reading is an on-going process; readers not only comprehend, question, and evaluate the text, but also create new meaning from the text and create and share their new knowledge with others. During L2 literacy acquisition, readers dialogue in various ways: between their social values and prior experiences, between L1 skills and L2 profi- ciency, by themselves, between texts (intertextuality), and in the social world (Koda 2007; McElvain 2010). Dialogic also involves dialogue between an L1 and an L2 self, a process that helps ELLs to recognize themselves, to co-construct meaning while read- ing, and to become social beings in their new culture (Bakhtin 1986). Bakhtin’s (1986) dialogic discourse was embedded in the study as I analysed the data and reconstructed the participants’ voices. Jaewon and Hiroki dialogued by them- selves–between an earlier and a later self (Bakhtin 1986)–and with the text in their active understanding of two different perspectives of the same historical event. Jaewon and Hiroki used dialogic thinking skills as bridges to culturally unrelated texts. Within this domain, they played active roles in meaning-making processes. Dialogic domains appeared to provide praxis of action and reflection (Freire 1970). Critical domain Literacy enables one to read the world and build critical consciousness; to perceive social, political, and economic oppression; and to take action against the oppressive Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 16 of 21 elements of society (Freire 1970). Hiroki and Jaewon co-constructed meaning while reading without violating the spirit of the work. This domain is the creation of mean- ing with the reader co-constructing public and private aspects of meaning from the text. ELLs, as historical, social, cultural, and political beings, create their critical con- sciousness to read and understand the text in its context (Freire 1970). While reading Follow the Dream, Hiroki considered two concrete facts: Christopher Columbus discovered America from the European perspective, but from the Native American perspective, Columbus was an invader who came to America without per- mission. Hiroki’s dialogue indicated that he associated with Follow the Dream, empha- sizing Columbus’s discovery, but he also acknowledged the concept of invader, realizing that Christopher Columbus was not an expected or “invited” guest, reflecting Encounter. Conclusion and Pedagogical Implications ELLs make meaning while reading stories within the domains or about the particular domains, depending on the texts at hand. While ELLs make meaning of the situated contexts (Gee 2008), these domains embrace these four ELLs’ ethnic and cultural heri- tages, L1 literacy, and real-life experiences, acknowledging them as active knowledge- generators who co-construct meaning from the text (Bakhtin 1986; Freire 1970). Employing certain domains also increases the critical thinking skills and degree of dia- logue among ELLs, with the texts and within social contexts, appropriately implement- ing proper domains under each circumstance (Bakhtin 1986; Freire 1970; Perez 1998; Wells 2007). ELLs are situated in a learning community (Lave and Wenger 1991), play- ing the “role” of a “certain kind of person”, shifting their “socially situated identity” through the construction of meaning (Gee 2008; Kim 2009b). In line with Koda’s (2007) explanation of ELLs’ uniqueness, the ELLs in my study apparently used two languages and cultures to construct meaning while reading. It is vital to apply these factors in our daily teaching. The uniqueness of ELLs’ comprehen- sion of texts appeared in the four examples. First of all, ELLs use both of their lan- guages and their reading processes developed from intertwined knowledge and experiences from the two languages and cultures. As August and Shanahan (2006) indicated that ELLs, “take advantage of cognate relationships between their first lan- guage and English to understand English words, an important precursor to compre- hension” (p. 5). Maria’s case clearly demonstrated how she used her knowledge of the Spanish piñata to explain to me in English. Evert also used his Swedish skill to under- stand memory. Secondly, ELLs also extend their meaning construction further to develop their critical thinking as interweaving and testing these two languages (e.g., Jaewon’s and Hiroki’s cases). Third, ELLs developed their ownership of learning as connecting to their L1 culture and personal experience of arriving in the new country (e.g., Maria’s and Evert’s cases). Fourth, their oral proficiency (e.g., Maria’s case) seems also crucial to developing their L2 practice. It is very important to understand these processes; teachers need to encourage ELLs to use their first and second languages as well as both cultures as part of their L2 practice. Teaching ELLs to practice and use these domains will maximize the benefit the reader derives from the reading process. Rosenblatt (1993) stated, “for a historical work or a political speech that uses many so-called literary devices, it will be especially Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 17 of 21 important to decide what major stance to adopt” (p. 383). There is not a single “cor- rect interpretation,” but the open-minded admission of several points of view. The 2002 conclusion from the International Reading Association clearly stated that “when readers are given cognitive-strategies instruction, they make significant gains on mea- sure of reading comprehension over students trained with conventional instruction” (p. 13). The panel also emphasized that teaching a variety of reading-comprehension stra- tegies in contexts and content areas leads to increased learning of these strategies. It is vitally important for teachers to understand these domains to teach various reading strategies. Teachers need to understand how ELLs connect to the text and comprehend it using various strategies within the domains (Park and Kim 2011). Providing and practicing these domains is crucial. By being familiar with these domains, ELLs will be ready to comprehend the texts. As the panel recommended, more intensive instruction and modelling, employing effective instruction, and transactional practices derived from research are more suc- cessful in improving reading and connecting ELLs to the texts and lead them to be academically successful (August and Shanahan 2006; Kim 2009b). Within the domains or about the domains, students develop ownership of learning and develop their dynamic identities (Kim 2009a). These dialogic responsive reading domains will be helpful in obtaining content knowledge in all the subjects and skills routinely taught in schools and in enabling students to create their own ownership of learning and willing- ness to learn (Au 1993), reflecting the power of literacy (Freire 1970). Using think aloud protocol, we practice these domains with ELLs. I provided simple samples of questions while stimulating the ELL’s reading processes. As the summary of International Reading Association (2002) concluded, teachers are encouraged to explain specific strategies to enhance each domain and model them for students. These strategies improve students’ reading comprehension. Teachers were encouraged to model their own thinking processes and to stimulate students to ask questions and discuss possible answers among themselves. These responsive domains keep students engaged in their tasks and demand active involvements, as well as ongoing thinking. Practicing these responsive reading domains is fundamental for adopting them. According to Gee (2008), ELLs learn better when they use and develop precursors (interchangeably necessary skills, knowledge, and/or social languages), which facilitate becoming a member of the affinity group. For example, ELLs drew upon their own cul- tural knowledge to make sense of a cultural domain. Using culturally meaningful or familiar reading materials that provide strong precursors also appeared to facilitate reading comprehension (August and Shanahan 2006). Consequently, ELLs apprehend and master this domain without difficulty, since they have a well-developed precursor. To master critical and dialogic domains, ELLs need to practice several precursors such as cultural domain, critical thinking, and so forth. This networking is crucial for schooling and language learning. Practicing these domains using think-aloud teaching protocols (Weaver 2002) must be embedded in daily teaching, fostering cultural conti- nuity and critical consciousness (Freire 2000). Situating meanings requires personalized experience of a domain and the ability to situate meaning in the terms of that experi- ence (Gee 2008). Praxis is crucial to mastering content and concepts, and becoming members in or about the domains. Domain praxis is based on genuine dialogue with learners, accepting and valuing their own voices, sharing their cultural and historical Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 18 of 21 knowledge and experiences, and inquiring into their reading of the word and the world, recognizing that the readers are rewriters (Bakhtin 1986). Rewriting the text as a ELL entails a critical perception of the word and the transformation of the world through practical action and reflection (Freire 1970; 2000). Cultural, aesthetic, and efferent domains empower ELLs and will expand their own learning, as they become competent and confident learners. Critical and dialogic domains transform knowledge so that ELLs can read any text (culturally or not cultu- rally related) by forging a connection with it. By scaffolding their knowledge with cap- able peer support, ELLs can grow into cooperative partners (Vygotsky 1978). Educators are cultural workers promoting dialogic thinking to create bridges to critical thinking (Freire 1970; 2000). Educators should encourage ELLs to share their cultural strengths with others in the mainstream classroom. With this guidance, ELLs will be empowered to read words and competently to read the world. Endnotes This is a part of the larger study. This study used only eight protocols: Protocol 1 (Jae- won reading Woodcutter and Tiger Brother), Protocol 4 (Jaewon reading Encounter), Protocol 5 (Hiroki reading Encounter), Protocol 8 (Hiroko reading Follow the Dream), Protocol 9 (Jaewon reading Follow the Dream), Protocol 10 (Maria reading I Hate Eng- lish), Protocol 11 (Maria reading Family Pictures), and Protocol 12 (Evert reading Wil- frid Gordon McDonald Partridge). Abbreviations ELL: English Language Learner; L1: First Language; L2: Second Language Acknowledgements I am thankful to Dr. Suresh Canagarajah at Pennsylvania State University for his thorough review of my first draft. I am also deeply grateful to Dr. Jane Applegate at the University of South Florida for her steadfast support throughout the writing process. All errors and omission are my own. Author's information Deoksoon Kim is an Assistant Professor of Foreign Language Education and Second Language Acquisition and Instructional Technology at the University of South Florida and an iTeach Fellow at USF. Her research involves second language and bilingual processes from a sociocultural-constructivist perspective, L2 reading and literacy, integrating instructional technology in teacher education, and ethnic minority students. She has published in Computers and Education, English Leadership Quarterly, TESOL Journal, Journal of Reading Education, TESOL publications, a Research Anthology chapter sponsored by AERA, and elsewhere. She delivered keynote speeches at the International Qualitative Research Conference in 2007 and 2010. Competing interests The author declares that they have no competing interests. Received: 7 June 2011 Accepted: 16 December 2011 Published: 16 December 2011 References Alexander, PA, and E Fox. 2004. 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Submit your manuscript to a journal and benefi t from: 7 Convenient online submission 7 Rigorous peer review 7 Immediate publication on acceptance 7 Open access: articles freely available online 7 High visibility within the fi eld 7 Retaining the copyright to your article Submit your next manuscript at 7 springeropen.com Kim Multilingual Education 2011, 1:2 http://www.multilingual-education.com/1/1/2 Page 21 of 21 http://www.springeropen.com/ http://www.springeropen.com/ Abstract Background L2 Reading Research Dialogic Responsive Reading Domains as Peripheries of Situated Meaning Methods Setting and Nature of the Instruction Participants Materials Data Collection Data Analysis Results ELLs’ Cultural Perspective ELLs’ Lived-Through Experiences ELLs’ Efferent Reading ELLs’ Dialogic Meaning Construction ELLs’ Critical Reading to Learn Discussion L2 Responsive Reading Domains L2 Responsive Reading Through Emergent Domains Cultural domain Efferent domain Aesthetic domain Dialogic domain Critical domain Conclusion and Pedagogical Implications Endnotes Acknowledgements Authors' information Competing interests References work_4fqbto43arfzpdzbvwdqglv5de ---- PII: 0010-0285(76)90010-4 COGNITIVE PSYCHOLOGY 8, 311-335 (1976) Interference with Real World Knowledge CLAYTON H. LEWISANDJOHN R. ANDERSON The Univrrsiry of Michigan Two experiments are described in which subjects studied made-up, fantasy facts about well-known persons and then were asked to verify actual facts about these persons. Reaction time to the actual facts was longer the more fantasy propositions studied about a person. Reaction time was also longer when the verification test involved a mixture of actual and fantasy facts rather than just actual facts. A mathematical version of the ACT model (Anderson, 1976) was fit to the data. It provides a satisfactory fit, better than an alternate model. However, some’of the parameter values estimated for the ACT model seemed unreasonable. A number of recent studies have supported the idea that the more propositions a subject knows about a concept the slower he is to verify any one of them. (See Anderson & Bower, 1973; Anderson, 1974; Thorndyke & Bower, 1974.) Anderson (1976) has developed the ACT model to account for these findings. These studies have employed artificial “facts” learned by subjects in an experimental situation. Intuitively, it seems unlikely that these results would generalize to the verification of propositions which are part of a subject’s stock of actual facts. If these results did generalize it would seem to imply that the more one knows about a concept, the slower he would be to verify any particular fact about that concept. In the experiments reported below we explored this matter by having subjects learn varying numbers of artificial facts about well-known people. We then examined the effect of the number of artificial facts learned about a person on the time to verify actual facts about him. Since these experiments involve possible interference of propositions learned in an experimental situation with retrieval of actual knowledge they are also of interest in considering whether memory is so structured that information learned under different conditions can be scanned independently if task demands warrant. These experiments are concerned with whether experimentally learned material will interfere with pre-experimental material. A similar question This research was supported by Grant GB-40298 from NSF. We would like to thank the reviewers of this article for their helpful suggestions. The ordering of the authors is arbitrary. Address correspondence to Clayton Lewis at Human Performance Center, 330 Packard Road, Ann Arbor, MI 48104, and to John Anderson at Department of Psychology, Yale University, New Haven, CT 06520. Reprint requests should be sent to John Anderson. 311 Copyright 0 I976 hy Academic Prew Inc. All rights of reproduction in any form reserved. 312 LEWIS AND ANDERSON has been subject to extensive experimental analysis-the question of extraexperimental sources of interference (e.g., Postman, 1962; Under- wood & Ekstrand, 1966; Underwood & Postman, 1960). It had been hy- pothesized that high frequency words would be subject to more rapid for- getting because of greater interference due to more competing extra- experimental associations. The initial results in this investigation were largely negative. However, these experiments tended to confound factors such as form class and imagery rating with frequency. There is a recent set of experiments which seem more favorable to the hypothesis of extraex- perimental sources of interference. These have controlled for form class and imagibility. M. Fehling (personal communication) has found poorer re- tention for high frequency paired associates. Kieras (1974) has found poorer recall for sentences composed of high frequency words. Perlmutter, Harsip, & Meyers (1976) also report longer recognition latencies to pairs composed of high frequency pairs. An experiment by Slamecka (1966) is very similar in intent to the experiments to be reported here. He looked at the effect of learning interfering experimental responses on subject’s ability to recall free associations to a stimulus item. There was no effect of these experimental associations, whether measured by frequency of recall or by response latency. The experiments to be reported here will rely on a more accurate and sensitive latency measure than in Slamecka’s research. However, his results clearly do not favor the prospects of getting an effect of experimentally acquired facts on pre-experimental facts. TABLE 1 EXAMPLES OF MATERIAL USED IN THE EXPERIMENT Examples of artificial facts studied George Washington wrote Tom Sawyer. Napoleon Bonaparte was from India. Napoleon Bonaparte was a singer. Napoleon Bonaparte is a liberal senator. Napoleon Bonaparte had a ranch. Examples of test probes Actual facts 0 Fidel Castro is Cuban. 1 George Washington crossed the Delaware. 4 Napoleon Bonaparte was an emperor. Fantasy facts 1 George Washington wrote Tom Sawyer. 4 Napoleon Bonaparte was from India. False 0 Fidel Castro was a Texan politician. 1 George Washington is a swimmer. 4 Napoleon Bonaparte was a humorist. INTERFERENCE WITH ACTUAL KNOWLEDGE 313 FIG. I. A schematic ACT representation of some of the information attached to George Washington. Table 1 illustrates the materials used in these experiments. A number of fantasy facts, not actually true, were studied about various well-known public figures. After learning these facts, subjects had to respond true or false to test probes that were either actual facts, fantasy facts, or false sentences (neither true in the real world nor learned during the experi- ment). Subjects were instructed to respond true to fantasy facts as well as to actual facts. The digits in Table 1, not shown to the subject, in- dicate how many fantasy facts were studied about the individual. The major question is whether the number of fantasy facts studied about a person would influence the speed with which an actual fact about that person can be verified. According to the ACT model the subject’s knowledge about a person in the experiment can be represented schematically as in Fig. 1. Figure 1 illustrates a very simple network in which the subject, George Wushing- ton, is connected to a number of predicates. Figure 1 is a simplification of the ACT representation which is similar to the HAM model of Ander- son and Bower (1973). We are using this simplification to ease the task of exposition. If a given proposition is to be verified, nodes representing its subject and predicate are identified in memory, and search processes are started from both nodes. These searches spread outward along all arcs from these nodes until they intersect, at which time a check is performed to determine whether the connection between subject and predicate matches the proposition to be verified. If it does, the appropriate response is made. This search mechanism is similar to that proposed by Collins and Loftus (1975). The spread of search processes from a node is assumed to be a limited-capacity parallel process (see Townsend, 1974). This means that the more arcs are encountered at a node the slower will be the progress of the search along each arc. Referring to Fig. 1 it will be seen that the process of verifying an actual fact about George Washington will accordingly be slowed down by the presence of the fantasy fact about him. If additional propositions with the same predicate as an actual fact were studied, verification of the actual fact would be slowed for the same reason, since search also proceeds from the predicate node. 314 LEWIS AND ANDERSON EXPERIMENT I Experiment I allows a test of these predictions. The number of arti- ficial facts studied about a person was varied from zero to four. So that the effect of extra arcs at the predicate node could be assessed, predicates from actual facts to be tested were used in two fantasy facts or were not used at all in the fantasy facts. Method Materials. A list of 40 well-known actual facts about public figures was prepared, two facts for each of 20 individuals (see Appendix). Each fact was of the form NAME PREDICATE, the 40 predicates being all different. From these 40 facts materials were constructed for a learning phase and for a later reaction time test phase. One of the two actual predicates associated with each name was randomly designated a study predicate, the other being reserved. Reserved predicates were not used in constructing fantasy facts for study. A total of 40 fantasy facts was constructed by repairing names and study predicates, four fantasy facts being produced for each name in treatment 4, three for each in treatment 3, and so on for treatments 2, 1, and 0. These 40 propositions, together with six filler propositions constructed from similar materials, formed the study materials for the subject. To form the test materials the original 40 actual facts were added to the 40 fantasy facts, and 80 new false propositions to be used as foils were constructed by repairing names and predicates in such a way that among the test materials each name and each predicate appeared equally often in real or fantasy facts as in foils. Note that all fantasy facts and all false facts used predicates that came from actually true facts. One motivation for this was to assure that the predicates used for the false facts and the fantasy facts had credibility as the sort of thing that might be said of a public figure. Building fantasy facts in this way has the disadvantage that their predicates were connected to other individuals in a nonsystematic way; for example, in the fantasy fact “ George Washington wrote Tom Sawyer” the predicate is strongly associated with another individual, while this is not true of “George Washington was a scientist.” Randomizing the use of predicates and individuals was intended to deal with this problem. Another point to note about the fantasy facts is that many were inconsistent with known facts. This gave the fantasy facts a different character from obscure actual facts that subjects had not seen before. It is not clear how results might differ if such true but not known facts were used. It was intended that each subject have his own randomly constructed set of materials. However, through an oversight only nine different sets of materials were used. Subjects. Twenty-six female subjects from the Human Performance Center paid subject pool participated in the experiment in groups of one to four. Of these, three failed to perform sufficiently accurately in the test phase of the experiment and were eliminated. Subjects were paid $2.00 per hour for their services. Procedure. Study and test materials were presented and responses and response times collected by an IBM 1800 computer with four cathode ray tube terminals, each in a semi-isolated booth. The GEPS II programming system (Kieras, 1973) was used, allowing up to four subjects to be run independently at one time. A subject was first given a list of the 20 names used in the materials, plus those appearing in filler items, and asked to mark any which were unfamiliar. The names were well known to the subjects: the mean number marked was .2. No aid was given to subjects’ recognition beyond mentioning a common nickname if one existed. The subject then entered the study phase of the experiment. The study propositions were presented one at a time on the CRT screen. The subject was told to regard these INTERFERENCE WITH ACTUAL KNOWLEDGE 315 propositions as describing a fantasy world peopled by the individuals described. She was asked to write a short continuation of each proposition on a numbered sheet, then press a button to see the next proposition. The nature of the continuation was not prescribed beyond the requirement that it relate in some way to the subjects’ understanding of the proposition. Examples given in the instructions included adding embellishing detail and providing a reconciliation of the proposition with actually known facts. The 40 study propositions were presented in three random orders, preceded and followed each time by three filler items. The subject was asked not to consult her previous written continuations when seeing a proposition again but was free to use the same continuation again if she chose. To decrease the likelihood that the subject might try to memorize the study materials verbatim, she was told that the continuations would be used to assess her handling of fantasy materials and was not told that she would be tested for retention of propositions or continuations. The study procedure was self-paced and took about 50 min. On completing the study phase the subject entered the test phase of the experiment. Test propositions were presented one at a time on the CRT and the subject was told to press a true or false button as quickly as was consistent with reasonable accuracy. In particular, she was to respond true to any proposition which was an actual fact or which was one of the fantasy facts seen during study, and false to other propositions. To be sure the subject understood this requirement she was asked to write out in her own words the relevant part of the instructions and get the experimenter’s approval or clarification before beginning the test phase. The subject was free to choose which hand to use for true responses and which forfalse. After each response the subject was told whether she was correct or incorrect and the next item was presented after a delay of 1 sec. The test items were presented in three random orders to each subject, each order preceded and followed by six filler items and separated by rest periods. The test phase lasted about 50 min, in- cluding two rest periods. After the test phase the subject was given a list of the actual facts used in the experiment including fillers, and asked to mark any which had been unfamiliar when first encountered in the test or which the subject felt were untrue. The materials were reasonably familiar: the mean number of facts marked was S. Results For each subject, response times for correct responses for each type of test item were averaged, times longer than 5 set being treated as 5 set and times shorter than 200 msec being classed as errors. The sub- ject means were then averaged, and are shown in Fig. 2. The abscissa in Fig. 2 is fun: the number of fantasy propositions studied about the name in the test item. False test propositions and actual facts are broken down according to whether the predicate in the item was a study predi- cate or a reserved predicate; that is, whether the predicate in the test item was seen during the study phase or not. The subjects x conditions interaction mean square was used to estimate the standard error of a condition mean, which was 49.6 msec. This esti- mate may be too low given that a large number of conditions was used in a within-subjects design, but except where noted it is used below to give some idea of the reliability of differences in the data. The first aspect of the results to note is the increasing trend of time to verify actual facts with reserved predicates as fan increases. Because of 316 LEWIS AND ANDERSON em.-.* FALSE A.-.--A . . . . . . . . . . . . . FANTASY FACT - cNAL FACT - STUDY RESERVED PREMC*TE PREDICATE FIG. 2. Reaction times and accuracy in Experiment 1. the importance of this trend its reliability was assessed by calculating the value of a linear trend contrast for each subject and estimating the variability of this contrast directly rather than using the overall estimate of standard error. This computation indicates that the trend is quite sig- nificant (fz2 = 4.0, p < .OOl). Time to verify fantasy facts also increases with fan, (fSW = 2.8, p < .Ol) and verification of artificial facts takes longer than verification of actual facts of the same fan (t,% = 14.0, p < .OOl). On the average, actual facts with study predicates take longer to verify than those with reserved predicates (tgos = 2.0, p < .05), and the inter- action with fan is significant (t 508 = 2.3, p < .025). That is, the effect of fan is significantly less for those actual facts with study predicates. Time to reject false propositions increases with fan (f5,,6 = 5.5, p < .Ol). Propositions with reserved predicates can be rejected faster than those with study predicates (tSo6 = 10.1, p < .OOS). INTERFERENCE WITH ACTUAL KNOWLEDGE 317 Proportions correct for the various types of test items are also shown in Fig. 2. Errors tend to increase with fan. Discussion The basic predictions of the ACT model are borne out: Studying fantasy facts about a person slows down the verification of actual or fantasy facts about that person. Studying extra occurrences of a predicate slows down verification of facts using that predicate. The interaction be- tween prior use of predicate and fan was not expected. The higher the fan associated with a name, the greater the probability that the name would occur close to its study predicate during the study phase. Thus, there is a greater probability that the subject may notice and implicitly rehearse the relation between the name and its actual predicate. This might pro- duce decreased reaction time to the name-predicate combination thus causing the interaction between fan and prior use of the predicate. To account for the overall speed advantage of actual facts over fantasy facts one more feature of the ACT model must be described. Memory connections can have different strengths, and search energy is divided among connections in proportion to strength. It is reasonable to assume that connections making up fantasy facts are weaker than those making up actual facts, so that it takes longer to find a fantasy fact if it is present. The principle means for rejecting false propositions in the ACT model is by means of a process that waits a certain period of time for an intersection to occur. If an intersection does not occur in that period of time, a false response is generated. This waiting process is attuned to the various variables, such as fan, which can delay the occurrence of an inter- section for true probes. That is, the process waits longer for probes con- sisting of elements with greater fan. This accounts for at least the qualitative features of the rejection data: Rejection is slowed by fan and by extra use of predicate. The accuracy data in Fig. 2 are not accounted for directly by the ACT model. One may speculate that imperfect original learning is responsible for the misses in verifying fantasy facts, with the proviso that some sort of interference accounts for poorer learning of facts about names with higher fan. Another possibility is that guesses are produced after allowing processing to go on for some interval, so that items taking longer to process will get more guesses and hence more errors. This could account for the trend in errors for fantasy facts and false test items with study predicates. This sort of guessing model has been developed and tested by King and Anderson (in preparation) and Mohs, Westcourt, and Atkinson (1975). Note that while large differences in accuracy occur among the condi- tions the principle differences in latency cannot be attributed to differ- 318 LEWIS AND ANDERSON ences in speed accuracy tradeoff: Slower conditions are less accurate. It is possible that the accuracy differences do reflect differences in under- lying processing which would make comparison of latencies problematical, but we will argue below that the sort of model proposed by Mohs et al. can account for the accuracy data in a way that does not require serious reinterpretation of the latencies. While the ACT model is fairly well supported by these results, there is another kind of model which can also explain them. In the ACT model the interfering effect of fantasy facts occurs during search: Fantasy and actual facts are stored together in memory, and fantasy facts tie up search capacity when actual facts are being sought. In the other kind of model interference occurs because of a decision problem: Fantasy and actual facts can be searched independently, but the subject does not know in advance where to search for a test item. If the test item is an actual fact, but the subject searches first among his store of fantasy facts, a penalty is incurred which increases with fan. The simplest form of decision-interference model assumes that fantasy and actual facts are searched serially. If m fantasy facts can be searched in time d + me, d being a constant overhead and e the time to check one fact, and all actual facts can be searched in time A, and if actual facts are searched first with probability p , then the average search time for an actual fact with a name of fan m will take A/2 + (l-p) (d + me). The factor A/2 in this expression reflects the assumption that the correct proposition will be uncovered halfway through the test of actual proposi- tions. This formula accounts for the increase in verification time attendant upon fan. The main effect of predicate type on verification could be captured in this model at the expense of another parameter: The probability of starting search with actual or artificial facts could be allowed to vary according to the number of times the elements of the test item were seen during study. This is plausible, since if a subject could be certain that he had not seen a predicate during study he should never search his artificial facts at all. EXPERIMENT II Both search-interference and decision-interference models can account for the Experiment 1 data reasonably well. Experiment II was carried out in an attempt to separate these two models. Experiment II was very similar to Experiment I, the major change in procedure being that subjects were tested on actual and fantasy facts separately to minimize the decision problem that they may have faced in the Experiment I test in which these items were mixed. According to the decision-interference model there should be no effect INTERFERENCE WITH ACTUAL KNOWLEDGE 319 of fantasy facts on verification of actual facts if subjects know they are being tested only on actual facts. In the ACT model, interference should be just as great whether test items are mixed or not. A mixed test was also given to Experiment II subjects to provide a check on the compar- ability of the procedures, Another change in Experiment II was that some fantasy facts were presented more often than others during the study phase. According to the ACT model this should have the effect of in- creasing the strength of these propositions, and hence allowing faster re- sponses to these but also increasing the interference they cause. Because of the interaction of fan with prior use of predicates found in Experiment I and the possibility it suggested of implicit rehearsal occurring during study, it was decided to reserve in Experiment II all predicates associated with actual facts to be tested. Finally, only fans of 0, 1, and 4 were used, as it was felt these gave an adequate picture of fan effects. Method Maferids. The set of 40 facts about 20 names was used again, but the makeup of study and test materials was different from Experiment I. For each subject one of two groups of 10 names was selected at random and called the test group. Two names from this group were assigned randomly to each of the treatments 0, 1, lr, 4, and 4r. These treatment designations indicate the number of fantasy facts to be studied about the individual, and whether the fantasy facts will be repeated during study. Thus an individual in treatment 4r will have four fantasy facts each presented twice as often during study as the four fantasy facts about an individual in treatment 4. The predicates associated with the other group of names, the nontest group, were used to construct the fantasy facts. Altogether there were 20 fantasy facts. These 20 facts, together with six filler items, formed the study materials for the subject. In preparing the study materials for presentation each fantasy fact with a name in treatments Ir or 4r was repeated, so that these items were seen twice as often during study as items with names in treatments 1 and 4. There were three types of reaction time test blocks-pure tests of actual facts, pure tests of fantasy facts, and mixed tests of actual and fantasy facts. In each of these blocks there were an equal number of true and false probes. The false probes were constructed so that each name and each predicate appeared equally often in true and false probes. This was to prevent the names or the predicates from acquiring a response bias. To achieve this balance it was necessary to use some filler actual trues (constructed from the nontest group) and some filler falses. Subjects. Thirty female subjects from the Human Performance Center paid subject pool participated in the experiment. They were paid $2.00 per hour. Procedure. The procedure used in Experiment II was very similar to that used in Experi- ment I. Since a smaller number of fantasy facts was used subjects spent less time on the study phase, about 40 min. On completing the study phase the subject was given instructions describing three different types of tests she would encounter during the next part of the experiment. In each test, propositions were presented, responses collected, and feedback given exactly as in Experiment I, but the subject’s rule for responding was different for the three types of tests. In apurefantasy test the subject was to respond rrue only to items she remembered from the study phase, and false to all others. No actual facts were in- cluded in the materials presented in this kind of test. In apure acfual test the subject was to respond true only to actual facts. No fantasy facts were presented here. In a mixed test the 320 LEWIS AND ANDERSON subject was to respond true to actual or fantasy facts as in Experiment I. To ensure that subjects understood the types of tests they were required to paraphrase versions of the relevent parts of the instructions as in Experiment I before starting the test phase. Each subject received a series of six tests, two of each type, arranged in such a way that each type appeared once among the first three tests, with the last three being simply the first three in reverse order. These test orders were counterbalanced over subjects. Each test was preceded by a summary of the rules for responding, and the subject was told to consult her instruction sheet before proceeding. The test series took about 40 minutes. The familiarity of the materials was checked exactly as in Experiment I. An average of 0.9 names and 1.3 facts were marked as not known. Results Data for Experiment II were treated as described in Experiment I. The mean reaction time for correct responses are shown in Fig. 3 and the accuracy data is shown in Fig. 4. Test results are shown broken down by fan, the number of fantasy facts studied about the individual in a test item. They are also broken down according to which test type they come from- e-m.---* FALSE &-.-.A * . . . . . . . . . . . l FANTASY FACT A . . . . . . . . . . . A - ACWAL FAIZT - NOT RPEATED REPEATED I 1 I 1 I 1 FAN: 0 1 4 1 4 0 I 1 WXED TEST PURE FANTASY TEST PUR ACTUAL TEST FIG. 3. Reaction times in Experiment II. INTERFERENCE WITH ACTUAL KNOWLEDGE 321 mixed test, pure fantasy, or pure actual. Points designated repeated show results for those items for which the fantasy facts were shown twice as often during study. Thus items about individuals in treatment 4r appear as fan 4, repeated. The standard error of the 32 reaction time means in Fig. 3, estimated from the interaction mean square in a conditions x subjects analysis of variance, is 56 msec. Considering first the results for the mixed test, one can note a pattern of times similar to that found in Experiment I, with verification of actual facts being more rapid than verification of fantasy (tsss = 10.2, p < .005). Repetition makes verification of fantasy facts faster (tsss = 2.52, p < .Ol) and reaction time increases with fan (tsss = 3.59, p < .005). There is no interaction between the effect of fan and repetition on fantasy facts i: 899 = .71). Time to reject a false fact is also increased by fan 999 = 3.36, p < .005). Effects of fan and repetition on verification of actual facts are less clear. Their effect was investigated by computing a fan 4-fan 0 contrast for each subject and calculating its variability. The difference is marginally significant (tess = 1.47, p < . 1). There is no apparent effect of repetition on actual facts (tsss = .18). In the pure fantasy test the same effects of fan found in the mixed test appears for verification (t,,, = 4.86,~ < .OOS). The effect ofrepetition on verification is also significant (tsss = 2.44, p < .025). The effect of fan on rejection is marginally significant (tsss = 1.33, p < . 1). The fan x repetition interaction for rejection is not significant (tBss = .94, p < .2). 1 L I 1 I I FAN: 0 1 4 1 4 0 1 4 MlXED TESI PURE FANTASV TEST PURE ACTUAL TEST FIG. 4. Accuracy in Experiment Il. 322 LEWIS AND ANDERSON 95 _ , I I L I I I I I 1300 1400 1500 1600 1700 IS00 1900 2000 2100 REACTION TIME (MSECI FIG. 5. Speed-accuracy plot for Experiment II. The lines are intended simply to indicate test type. In the pure actual tests the effect of fan and repetition on verification was investigated as for the mixed test by computing a fan 4-fan 0 con- trast for each subject. The contrast is positive (tz9 = 1.97, p < .05); 21 of 30 subjects showed positive contrast, (p < .05 by sign test). The effect of fan on rejection time is marginally significant (tag9 = 1.55, p < .Ol). There is not a significant effect of repetition on either time to accept an actual fact (tss9 = .lO) or time to reject a false (t899 = .96). Comparison of the times for the three tests show that verification is faster in the pure tests than for corresponding items in the mixed test; actual facts are faster in the pure actual test (teg9 = 2.91, p < .OOS), and fantasy facts are faster in the pure fantasy test (rsg9 = 6.42,~ < .005). Similarly rejections are faster in the pure actual test than in the mixed test (tsss = 11.7, p < .005), faster in the pure fantasy test than in the mixed test (tsg9 = 2.77,~ < .005), and faster in the pure actual test than in the pure fantasy @SW = 8.08, p < .005). With respect to the accuracy data, the mixed test results in Fig. 4 are quite comparable to the Experiment I results in Fig. 2; in particular, accuracy for fantasy facts is poor and gets worse as fan increases. In the pure fantasy test, accuracy for fantasy facts is much better, but still decreases with fan. Figure 5 provides a plot of the accuracy in the 32 conditions of Experiment II against reaction time. As can be seen there is a general trend such that longer latencies are associated with lower reaction times. An analysis of Experiment I reveals a similar trend. Discussion Returning to the models proposed to account for the results of Experi- ment I, how do they fare now? The most important new facts to be TA BL E 2 PR ED IC TI O NS O F TH E DE CI SI O N- IN TE RF ER EN CE M O DE L FO R EX PE RI M EN T II FA N 0 1 4 z M ix ed te st Fa ls e, n ot r ep ea te d Fa ls e, r ep ea te d Fa nt as y fa ct , no t re pe at ed Fa nt as y fa ct , re pe at ed A ct ua l fa ct , no t re pe at ed A ct ua l fa ct . re pe at ed K, +A +d - - K, + A/ 2 + (I - P, ,,) d K, +A +d ie K ,iA +d ie , K, +d +d iP ,A K, +d +e ,+ P, A K, + A/ 2 + (I - P, ,,) (d + e) K, + A/ 2 + (I - P, ,)( d + e, ) P ur e fa nt as y te st Fa ls e, n ot r ep ea te d Fa ls e, r ep ea te d Fa nt as y fa ct , no t re pe at ed Fa nt as y fa ct , re pe at ed Pu re ac tu al te st Fa ls e, n ot r ep ea te d Fa ls e, r ep ea te d A ct ua l fa ct , no t re pe at ed A ct ua l fa ct , re pe at ed K, +A +( l -P ,,) d - K, + A/ 2 + (I - PJ d - K, id ie +P ,A K, +d ie ,.i P, A K, + d + e + P, A K, +d +e ,+ P, A K, +A +( l-P ,)( d+ e) K, +A +( l-P ,)( d+ e, ) K, + A/ 2 + (1 - P, ,)( d + e) K, +A /2 +( 1 -P ,)( d+ e, ) 2 K, +A +d +4 e K, +A +d +4 e, z K, + d + 2. k + P, A c? 2 K, + d + 2S e, + P, A E K ,+ A /2 +( l -P ,,) (d +4 e) 2 K, + A/ 2 + (I - P, ,)( d + 4e ,) $ 2 K, +d +& +P ,A F K, +d i4 e, .+ P, A G K, + d + 2. 5e + P, A z Kt + d + 2. 5e , + Pf A G E K, + A + (I - PJ (d + 4e ) Kf + A + ( 1 - P, ,)( d + 4e ,) Kt + A/ 2 + (1 - P, )(d + 4e ) Kt + A/ 2 + (I - P, )(d + 4e ,) E .W 324 LEWIS AND ANDERSON accommodated are, first, that fantasy facts have an effect on verification time even in the pure actual test; second, that verification is faster in the pure tests than in the mixed; and finally, that repetition speeds veri- fication of fantasy propositions. On first thought the first of these findings might seem to rule out the decision-interference model, since subjects should never examine any fantasy facts in the pure actual test. If one allows some degree of con- fusion on the subject’s part on this point, however, some decision-inter- ference is still expected. This hedge is made attractive by the fact that pure tests are faster. This lends some support to the decision-interference model, since it is a direct prediction from the smaller difficulty in deciding which facts to search in verifying an item. The effect of repetition on verification can be accounted for by assuming that the artificial facts studied more often can be scanned more rapidly. To provide a rigorous test of the decision-interference model we de- cided to test a mathematical expression of it. This involved trying to pre- dict the 32 reaction times displayed in Fig. 3. For the time being we are ignoring the large differences in accuracy across conditions; how these may be accounted for is considered below. The model involved the fol- lowing parameters: There is a time d to access the fantasy facts. It is assumed that the time to search the fantasy facts increases by an amount e, if not repeated, and e,, if repeated, for every fantasy fact searched. The difference between repeated and nonrepeated facts was to accommo- date the fact that subjects are faster to verify repeated fantasy facts. The fourth parameter was A, the time to access and search the actual facts. Then there were three probabilities of accessing the actual facts first: P,, for the pure fantasy test; P, for the mixed test; and P, for the pure actual test. Presumably, P, < P, < P,. Finally there are two param- eters K, and Kf which represent the encoding time, response time, and TABLE 3 PARAMETER ESTIMATES FOR THE DECISION-INTERFERENCE MODEL Description Parameter Estimate Time to access the fantasy fact Time to search a fantasy fact Time to search a repeated fantasy fact Time to access and search actual facts Probability of searching actuals in fantasy test Probability of searching actuals first in mixed test Probability of searching actuals first in actual test Encoding, response, etc. for true response Encoding, response, etc. for false response d e e, A p, PItI p, K, Kf 324 msec 73.5 msec 53.5 msec 181 msec 0 .78 .96 1310 msec 1391 msec INTERFERENCE WITH ACTUAL KNOWLEDGE 325 .I. fl ./ /’ ./ /’ / /’ i ./’ /’ .’ d’.’ . . . , d / /. /‘. *.A . ..* . . . . . *... .;;I . . . . . . . W’ FAN: 0 1 4 1 4 0 1 4 MlXED TEST PURE FANTASY TEST PURE ACTUAL TEST FIG. 6. Predictions of the Decision-Interference Model-to be compared with Fig. 3. other processes not associated with the search of memory for true and false probes. The equations giving the predictions of this model for the 32 condi- tions of this experiment are displayed in Table 2. The parameters of the model were estimated using the STEPIT program (Chandler, 1965), minimizing the squared deviation. These parameters are given in Table 3. Figure 6 displays the predictions of the model. It is to be compared with Fig. 3 which displays the actual data. The model does account for 91% of the variance among conditions, but the variance not accounted for is significant [F(23,844) = 2.137,~ < .005]. A source of difficulty for the model is the effect of repetition. The model predicts that repeated fantasy facts, since they are searched more rapidly, should interfere less with actual verification. Also, since more facts must be scanned in verifying actual or fantasy facts at fan 4 than at 326 LEWIS AND ANDERSON fan 1 the effect of repetition should be greater at fan 4 than at fan 1, but this does not appear in the data. These problems with repetition appear in extreme form in the predicted rejection times. Another difficulty is that the effect of fan on latency to an actual fact is predicted to be smaller in the pure actual test than in the mixed. Still another difficulty is that the model predicts the effect of fan to be twice as great for rejecting falses as accepting trues-because of the self-terminating nature of the search process. A further problem for the model is its failure to predict the change in relative speed of processing of fantasy facts vs false facts between the pure fantasy test and the mixed test. These defects could of course be alleviated by elaborating the model. One way to do this would be to abandon the serial search assumption of the present decision- interference model in favor of separate ACT-like searches of fantasy and actual facts. But the fit of the model as it stands is good enough to make the limited point that the data in hand do not rule out a decision-inter- ference model of some kind. Next we attempted to fit the ACT model as described by Anderson (1976) to the data. The actual equations used in fitting the ACT model are given in Table 4 using parameters described in Table 5. The reader may wish to refer to these tables while following the exposition below. The ACT model assumes that a subject responds true by finding an inter- section of search processes among the concepts in the probe and then checking the pattern of intersecting search paths to see if a true response is justified. In developing the predictions of the model we will consider separately the processes of finding an intersection and checking it. In the ACT model, search is carried out by an activation of memory nodes that spreads out from all concepts mentioned in a sentence. If the sentence is true, after a certain time has passed activation from all these sources will intersect. The time to respond to a sentence thus de- pends in part on how slowly or quickly intersection occurs. As an approx- imation we will assume that a sentence like George Washington crossed the Delaware has just two sources of activation-one for the subject, George Washington, and one for the predicate, crossed the Delaware. The time needed for an intersection to appear will depend on the rate of spread of activation from these sources along the path leading to the intersection. As an approximation, the time is given by where a sets the time scale, and R, and R, are the rates of spread from the subject and predicate, respectively. This approximation is used through- out Table 4 to yield predicted times for true probes. INTERFERENCE WITH ACTUAL KNOWLEDGE TABLE 4 PREDICTIONS OF THE ACT MODEL FOR EXPERIMENT II 327 FAN 0 I 4 Mixed test False, not repeated False, repeated Fantasy fact, not repeated Fantasy fact, repeated Actual fact, not repeated Actual fact, repeated Pure fantasy test False, not repeated False, repeated Fantasy fact, not repeated Fantasy fact, repeated Pure actual test False, not repeated False. repeated Actual fact, not repeated Actual fact, repeated K,+ Pm -!-- K, + Pm I 1, L L.’ f I”+1 f+l f+1 I - K,+ Pm - ‘+ 1 f+l fli Km +a(1 -i-p) - K, +a(1 +p/r) K,+Lp K,,+&p +.5) x x - K,, + h(, + ,519 x 1 K/+/S ____ I_+- I j-+1 f+l 1 &+P, ~ 1 1 -+ - f+l f+l K,+a(l +P) K,+a(l+p/r) Kr+Pm 1 L.’ f+4 f+I I Kr+Pm - L, i_ f+4 f-+1 K, +n(2.5 +plr) K,+&p+2) x K,+&p+2r) x K/+& 1 L.’ f+4 f-+1 I K,+& ~ ‘+ - 1 j-+4 j-+1 K,+a(2.5tp) K,+a(23+p/r) 1 K,+& - I 1 ‘+ -!- K,+Po ~ L.’ K/t&, ~ L.1 f f+l f+l f+l f‘+4 f+l K,+& I - L.' f+l ft1 K,+& K, + -I,(, + .5) x .x K, + iu @ t .5r) x 1 K,+P. ~ ‘+’ f+4 f+1 K,+ia(p+2) x K,+&t2r) x 328 LEWIS AND ANDERSON TABLE 5 PARAMETER ESTIMATES FOR THE ACT MODEL Description Parameter Estimate Strength of repeated artificial fact Strength of actual fact tested Total strength of actual facts Search rate Average number of actual facts Falsification rate, mixed test Falsification rate, fantasy test Falsification rate, actual test True constant, mixed test True constant, fantasy test True constant, actual test False constant 1.3 2.4 4.8 120 msec 3.9 235 msec 197 msec 76 msec 1212 msec 951 msec 1112 msec 1383 msec The rates R, and R, depend on the strength of the links leading toward intersection, (that is, the links making up the proposition being sought) relative to the total strength of all links attached to the source subject and predicate. For example, if the strength of links making up the target proposition is s, and the subject has links connected to it whose strengths total D,, then R, = s/D,. We calculate the relevant strengths as follows. The strength of links making up a nonrepeated fantasy proposition is arbitrarily set to 1 to establish scale. A repeated fantasy proposition has links of strength Y, and any actual fact has links of strength x. A parameter p was estimated as the total strength of all links, other than those representing fantasy facts, attached to a predicate or individual. We can now calculate times for intersection to occur for various kinds of probes in terms of these parameters. For example, consider a fan- four, repeated fantasy fact. The strength of links connected to the subject is 4r for the links representing the four repeated fantasy facts plus p for all other links, for a total of p + 4r. The link that leads toward inter- section is part of one of the repeated fantasy facts, and so has strength Y. So R, = rl(4r + p). There is only one fantasy fact attached to the pre- dicate, so similarly R, = r/(r + p). Plugging these rates into our approxi- mation of time to intersection gives a t .54r+p+ 5r+P - .-) r r 1 which simplifies to ~(2.5 + p/r). Times for other kinds of probes are computed in the same manner. We now must consider the time taken to check an intersection to see if the response true is appropriate. One thing this checking process must INTERFERENCE WITH ACTUAL KNOWLEDGE 329 make sure of is that any modifier connected to a candidate path in memory does not conflict with the proposition being sought. For example, in verifying the proposition “George Washington was a woman” one would not wish to respond true if a structure representing “It is false that George Washington is a woman” were found. We will assume that the time required to perform checking varies according to the conditions of test; this is a plausible assumption since there are presumably fewer possi- bilities that need to be checked in a pure test than in a mixed. In this way we will account for the speed differences between tests, given that the time for an intersection to be found, as computed above, depends only on the kind of item being verified and not on test type. Three separate “intercept” parameters were used, K,, K,, and K,, representing the time required for encoding, checking, and responding true in the mixed, pure fantasy, and pure actual tests, respectively. We can now calculate the total response time for a true sentence by adding time to find an intersection to the lumped estimate for encoding, checking, and responding. For example, if the fan-four, repeated fantasy fact considered above appears in the pure fantasy test, the total response time is calculated to be K, + 42.5 + p/r). The ACT model for falsification is not as well developed as for verification. It is assumed that a waiting process is set up and if there is not an intersection of activation after a certain period, a false response is initiated. It is further postulated that this waiting process is sensitive to variables like fan which affect the time for activation to intersect. So for probes of higher fan, the process will wait longer before initiating the false response. Let fi be the fan associated with the subject, and fi the fan associated with the predicate. Then, in Table 4 we assumed that the waiting time would be: (Il(l/fi + l/fi))p, where /3 establishes the time scale. This is the waiting time one would get if the waiting time were determined by the fastest of two exponential waiting processes- one associated with the subject and with mean time fiP and the other associated with the predicate with mean time f2p. The HAM model (Anderson & Bower, 1973) proposed that the falsification times were de- termined by a race between processes with independent exponential time distributions. However, we do not mean to endorse an exponential distribution of waiting times. We regard this equation as somewhat arbitrary and chose it because it had been used in fitting earlier fact- retrieval experiments (e.g., Anderson, 1974; Thorndyke & Bower, 1974). Many expressions relating reaction time to the fan of subject and predicate would have done as well. For instance, we might have used PcfI +f2>- To derive predictions for the false probes required that four additional parameters be estimated. We needed to know f, the mean number of pre-experimental links or number of actual facts. Also we estimated three 330 LEWIS AND ANDERSON values of /3 for the three test types; &, for the mixed test, Pe for the pure fantasy test, and Pa for the pure actual test. It seemed reasonable to estimate a different parameter for each test because the mean proces- sing time for true probes would be different in each test. The waiting process should adjust the amount of time it waited to reflect this fact. To see how predictions for rejection time were computed, consider a fan-four, repeated item occurring in the mixed test. The fan from the subject isf + 4 and from the predicatef + 1. Note that only the number of links enters here, not their strength, so the fact that the subject occurred in repeated facts does not matter. The waiting time is now given by Pm t 1 l 1 > -- f+4 Tf+ 1 i and the total response time is given by adding Kf, the time to respond false. The ACT model requires the estimation of 12 parameters, in contrast to the nine parameters for the decision interference model. The parameters estimated by the STEPIT program are given in Table 5. The predictions of the ACT model are shown in Fig. 7. As can be seen by comparison with Fig. 3, ACT does a good job of fitting the data. The predictions account for 98% of the variance. The variance not accounted for is not significant [F(20,899) = SOO]. Although the fit of the model is quite good some of the parameters estimated are a bit bizarre. Note that the total strength of links other than those in fantasy factsp, is 4.8 which is just twice the strength of one of the actual facts tested (x = 2.4). Given that there were two actual facts tested about each individual this means that these facts took up all the pre-experimental strength. Actually, the STEPIT program wanted to esti- mate a value ofp less than 4.8, but we constrained the value ofp to be at least 2x. Second, the value off, the number of actual facts, is 3.9. To avoid an out-and-out contradiction one could imagine that the actual facts tested were so salient, particularly over the course of repeated testing, that they accounted for nearly all the pre-experimental strength. It is also possible that more sensible values of X, p, and f could have been estimated without much changing the goodness of the fit. That is, with 12 parameters it is difficult to know how sensitive the estimation procedure is to each parameter value. Another possibility is that the adequacy of the simplified representation in Fig. 1 as an approximation is being strained, and that more complex network structures must be considered. For instance, Anderson (1976, Section 8.3) proposed an hierarchical INTERFERENCE WITH ACTUAL KNOWLEDGE 331 1-j :“:““” AU”yy m, , , , FAN: 0 1 4 1 4 0 1 1 MMED T E S T PURE PANTAS” T E S T PURE ACTUAL T E S T FIG. 7. Predictions of the ACT Model-to be compared with Figure 3. structure in which a separate node would be set up to collect experi- mental facts about George Washington. Such a model begins to look like a mixture of the ACT model described here and the decision inference model. As noted above we have so far ignored accuracy data: We have concentrated on establishing that these models are able to capture some of the principle latency effects. We will now consider how the models might be elaborated to account for accuracy effects as well. In discussing the Experiment I results the suggestion was made that failures in learning might account for some of the misses in verifying fantasy facts. This is apparently not an important factor, in the light of the Experiment II results, since accuracy for fantasy facts in the pure fantasy test is quite high. So what does account for the low accuracy in the mixed condition? A look at Fig. 5 reveals an orderly relation between accuracy and processing time: longer latencies go with lower accuracy. As with the Experiment I results this suggests a race model for errors, such as that proposed by Mohs et al., in which errors occur when a 332 LEWIS AND ANDERSON guessing process finishes before normal handling of an item is completed. Conditions in which normal processing takes longer will therefore show more errors. The effect of the race with a guess process is to systematically change the observed distribution of reaction times from the “true” distribution of reaction times that would have been obtained were it not for the guess process. Under reasonable assumptions about the dis- tributions of processing and guessing times the racing guess process tends to truncate the distribution of latencies since trials for which normal processing takes a long time tend to be turned into errors by the prior completion of the guess process. Thus the observed mean reaction times are less than the “true” mean reaction times. However, the ordinal rela- tions among the mean reaction times for the various conditions are preserved. The differences among conditions are also reduced because of this guess factor. The ordinal relation among the differences are not always preserved. The differences among longer reaction times tend to be more greatly reduced. Thus, the effect of this guess process is to produce a “shrinkage” of the true graph of reaction times into an ob- served graph like Fig. 3. This shrinkage is greater for longer reaction times. Despite this shrinkage, it seems likely that either the ACT or decision inference models could have been fit to the true times about as well as the observed times. This is because the shrinkage preserves all ordinal relations among means and does not wildly alter ordinal relations among differences. The fit of the models to the observed times gives a good indication of the fit to the true times, could that have been obtained. The decision interference model might have given a somewhat improved fit to the true data since it did overpredict the size of some of the observed differences at long reaction times. More thorough investigation (such as actual model fitting) of the effects of extending the ACT and decision interference models to include a racing guess process would re- quire consideration of a number of further points including biasing of guesses, possible changes in the guess processes under different test conditions, and the portion of normal processing with which the guess process is to race. We believe more evidence would be required to adequately motivate choices about these matters. SUMMARY AND CONCLUSIONS These two experiments have uncovered two facts which we feel have important implications for the retrieval of information from memory. First, it was shown the more new facts learned about an individual the slower subjects were to retrieve facts already well learned about the in- dividual. Second, it was shown that subjects were slower when the range INTERFERENCE WITH ACTUAL KNOWLEDGE 333 of possible facts they must verify was larger. That is, they took longer in the mixed than the pure fantasy test. Thus, we have found evidence for two distinct types of interference to the retrieval process. Two models were presented to account for this pattern of data. The decision interference model proposed that the well established preexperi- mental facts were stored in one location and the fantasy facts were stored in another. The effect of number of fantasy facts on actual facts was due to subjects sometimes searching the fantasy facts before the pre-experimental. The advantage of the pure testing context arose because subjects would more often search the correct location first. The ACT model proposed that the information was stored together. The effect of fantasy facts on pre-experimental was due to a slowing down of the activation rate. The advantage of a pure testing context was attributed to the greater efficiency of the process that checked the path of intersection. Neither of the two models gave totally satisfactory quantitative fits. The decision-interference model mispredicted some important quantitative relations while some of the parameters of the ACT model took on somewhat bizarre values. We suspect the deficiencies of both models could be remedied with further complications, but such complica- tions did not seem justified. Each model accounts naturally for one of the main two interference effects, but had to be modified to accommodate the other. This serves to indicate the importance of these two effects to a theory about the retrieval’,, of real-world knowledge from long-term memory. APPENDIX Facts Used as Materials GEORGE WASHINGTON CROSSED THE DELAWARE. GEORGE WASHINGTON CHOPPED DOWN A CHERRY TREE. NAPOLEON BONAPARTE WAS FRENCH. NAPOLEON BONAPARTE WAS AN EMPEROR. JULIUS CAESAR WAS A ROMAN LEADER. JULIUS CAESAR WAS ASSASSINATED. FIDEL CASTRO IS CUBAN. FIDEL CASTRO IS A COMMUNIST. CHRISTOPHER COLUMBUS SAILED TO THE NEW WORLD. CHRISTOPHER COLUMBUS WAS AN EXPLORER. ABRAHAM LINCOLN FREED THE SLAVES. ABRAHAM LINCOLN GAVE THE GETTYSBURG ADDRESS. JOSEF STALIN WAS A RUSSIAN. JOSEF STALIN WAS A DICTATOR. 334 LEWIS AND ANDERSON HENRY AARON PLAYS BASEBALL. HENRY AARON BROKE A SPORTS RECORD. GALILEO GALILEI WAS A SCIENTIST. GALILEO GALILEI WAS ITALIAN. BEBE REBOZO LIVES IN FLORIDA. BEBE REBOZO IS NIXON’S RICH FRIEND. WALT DISNEY MADE MOVIES. WALT DISNEY CREATED MICKEY MOUSE. GOLDA MEIR IS ISRAELI. GOLDA MEIR IS A WOMAN. SPIRO AGNEW WAS VICE PRESIDENT. SPIRO AGNEW RESIGNED HIS OFFICE. ELIZABETH TAYLOR IS AN ACTRESS. ELIZABETH TAYLOR MARRIED RICHARD BURTON. LYNDON JOHNSON HAD A RANCH. LYNDON JOHNSON WAS A TEXAN POLITICIAN. JOHN LENNON IS ENGLISH. JOHN LENNON IS A SINGER. MARK SPITZ IS A SWIMMER. MARK SPITZ WON OLYMPIC MEDALS. MARK TWAIN WROTE TOM SAWYER. MARK TWAIN WAS A HUMORIST. TEDDY KENNEDY IS A LIBERAL SENATOR. TEDDY KENNEDY IS FROM MASSACHUSETTS. MAHATMA GANDHI WAS FROM INDIA. MAHATMA GANDHI WAS A NONVIOLENT LEADER. REFERENCES Anderson, J. R. Language, memory, and thought. Hillsdale. NJ: Erlbaum Associates, 1976, in press. Anderson, J. R. Retrieval of propositional information from long-term memory. Cognitive Psychology, 1974, 5, 451-474. Anderson, J. R., & Bower, G. H. Human associati\te memory. Washington: Winston, 1973. Chandler, J. P. STEPIT. Program 9OPE66, Quantum Chemistry Program Exchange, Indiana University, Bloomington, IN, 1%5. Collins, A. M., & Loftus, E. F. A spreading-activation theory of semantic pro- cessing. Psychological Review, 1975, 82, 407-428. Kieras, D. E. Analysis of the effects of word properties and limited reading time in a sentence comprehension and veri’cation task. Unpublished doctoral dissertation. University of Michigan, 1974. King, D. R. W., & Anderson, J. R. Long-term memory search: An intersecting activation model. In preparation. Mohs, R. C., Westcourt, K. R. & Atkinson, R. C. Search processes for associative structures in long-term memory. Journal of Experimental Psychology: Genera/, 1975, 103-121. Perlmutter, J., Harsip, J., & Myers, J. L. The role of semantic knowledge in retrieval INTERFERENCE WITH ACTUAL KNOWLEDGE 335 from episodic long-term memories: Implications for a model of retrieval. Memory & Cognition, 1976, in press. Postman, L. Extra-experimental interference and the retention of words. Journal of Experimental Psychology, 1%1,61, 97- 110. Slamecka, N. J. Differentiation versus unlearning of verbal associations. Journal of Ex- perimental Psychology, 1%6, 71,822-828. Thomdyke, P., & Bower, G. Storage and retrieval processes in sentence memory. Cog- nitive Psychology, 1974, 5, 515-543. Townsend, J. T. Issues and models concerning the processing of a finite number of inputs. In B. H. Kantowitz (Ed.), Human information processing: Tutorials in performance and cognition. Hillsdale, NJ: Lawrence Erlbaum Associates, 1974. Underwood, B. J., & Ekstrand, B. R. An analysis of some shortcomings in the interference theory of forgetting. Psychological Review, 1966, 73, 540-549. Underwood, B. J., & Postman, L. Extraexperimental sources of interference in for- getting. Psychological Review, l%O. 67, 73-95. (Accepted February 23, 1976) work_4ixr6muftzgwjioesvt5mkuzjm ---- SYMPOSIUM open access: nothing much new (or very little, anyway) terrell carver School of Sociology, Politics & International Studies, University of Bristol, 11 Priory Road, Bristol BS8 1TU, UK E-mail: t.carver@bristol.ac.uk doi:10.1057/eps.2015.86; published online 15 January 2016 Abstract Open Access has been around for many years. The only new developments of pressing interest are primarily related to UK university and research management bureaucracies. It is unlikely that the laws of copyright – which protect academic and other authors in various ways – will disappear, and certainly not overnight. Commercial publishers will find a business model that sustains them, and experimentation in novel forms of information dissemination will continue. Current rights in intellectual property are of course subject to critique and change, but internet access to information has not and will not suddenly dissolve the basic economics of information production and consumption. Keywords open access; publishing; copyright The online version of this article is available Open Access I t is of course important to get on board with the latest, and be up to date with the new. It is even impor- tant of course to anticipate change, and get ahead of the game. Being behind the curve is nowhere to be, of course. Hence the flurry of meetings, papers, day-long (even two-day) workshops, open fora, seminars, roundtables, brief- ings, draft procedures, proposed mech- anisms, information sources, blogs and posts, publicity, news stories and gen- eral twitter-storms of interest in – ‘Open Access’ (OA). However, it might just be a good idea to step back (600 years, if necessary) and get a grip on this. It might also be a good idea to turn on a cold shower and get under it. The reason for this counter- move is political in the broad sense. While there may not (or perhaps may) be con- spiracies ‘out there’, there are certainly vested interests at work, and most prob- ably unholy alliances and strange bedfel- lows. But people, such as ourselves in political science, are ‘coming from’ differ- ent places, because they are located dif- ferently. They have different ambitions, european political science: 15 2016 (183–190) & 2016 European Consortium for Political Research. 1680-4333/16 www.palgrave-journals.com/eps 183 http://www.palgrave-journals.com/eps perceptions and reactions. It is not ‘one world’, and we are not ‘all in it together’. The UK is not – as was hyped – going to lead the world in an OA crusade. Sometimes, like Christopher Columbus, you can get lucky by sailing in the wrong direction. But it does not happen often, and – given the two-years or so since the publication of the ‘Finch Report’ (Working Group on Expanding Access, 2012) – we can afford a backward glance and then consider the way forward, which, in the case of the UK, is something of a U-turn. We in global political science now have the benefit of hindsight, and would do well to get an overview. But where do we start? Even to mention the (now dreaded) words ‘Finch Report’ is to contextualise Open Access to very particular aspects of UK politics, very particular ministerial (and other) projects, and very particular responses and ramifications. The over- view analysis below argues that there are, possibly, opportunities and signifi- cant changes arising through Open Access for the world at large, but that threats (to various more or less valuable interests and practices, particularly in academia) are so far confined to the UK (and indeed possibly to some sections and sectors of it), and rather unlikely to leak out else- where. If you are a UK-based academic, you should be on your guard, even if you are also pro-OA – and on your charger. If you are otherwise or elsewhere, chill out and put it on the backburner. The world is always changing. IN THE BEGINNING … Instead of starting with Project Guten- berg, let’s start with the guy himself and his press. This is the model of self-pub- lication in the machine-age, that is, say what you want, get a medium, get it out there. Maybe you make money if you want, but anyway you have incurred some costs, if only your time, opportunity costs, and maybe some overheads (you have to eat and live, after all). Since then ‘we’ (now mostly the whole world population) have been living in various zones of legal and other authoritative modes of restric- tion on ‘speech’, but also various protec- tions of authorship rights and intellectual property. The latter of course may be disregarded by you; if you don’t care who uses your work for whatever purpose, then no one else does, either. Where there is ‘free speech’, there is ‘free publication’, in the sense that you can say what you like in a medium you can afford (even ‘Jesus saves’ on the street corner costs some- body something), provided that you stay within the criminal law and don’t incur civil liabilities (or pose a security threat). Posting anything on the internet isn’t really any different, provided you can get a digital device and some server-space, and others can find your words, pictures, songs, verses, videos, animations and the like. It’s easy to say that your materials are ‘freely’ accessed, and of course your readers and viewers may not be paying- per-view, but they have their own costs and overheads associated with enjoying your labours. You could ask them for donations, if you wanted; this is surpris- ingly effective (and also works for ‘Jesus saves’ on the street corner). If you care about the use, re-use and attribution of authorship to your work, don’t worry. It’s still yours, because you’ve tacitly asserted your rights (as they may be locally defined), and if you want to get a lawyer to chase infringers and miscreants, then that’s just fine if you pay their bill, so ‘good night and good luck’. However, if you want to cover your costs and maybe make a profit, then you can set up a shop (of some sort), find paying customers, and attempt to collect the ‘It might also be a good idea to turn on a cold shower and get under it’. european political science: 15 2016 open access184 money safe from banditry. You can try to do all this yourself, or use your capital (or day-job) to hire others to help. (And you’ll need an accountant and lots of time to do paperwork.) But don’t worry, there are any number of publishers – and pub- lisher-type outfits – who are there to help, quite freely, but probably not ‘for free’, that is, gratis. And they will probably want to stay in business by making more money than you do. So let’s be clear. If you want to self- publish and self-market, with or without payment or profit, then go right ahead. However, if you want to get some help with producing and marketing your work, then it is there to be had. If you can get good help for nothing, then great! But famously you get what you pay for, and your only redress if you don’t like a gratis service is moral suasion and going else- where. However, if you sign a contract with a publisher (even religious ones, as a rule, miracles being past their sell-by dates), then there will be rights and duties on either side. You can judge the terms, and then sign or not, maybe go else- where, or revert to self-publication and see how you do. You may or may not like any given publisher’s terms, personnel, business model, tax arrangements, loca- tion, work practices or balance sheet. But there are lots to choose from. Publishers are not all the same, and you can always get an agent (for a cut) and see how you do ‘out there’ on the market as an author. Academic work is no excep- tion. Anyone who thinks that universities, their employees and products are in a ‘zone of exception’ away from commercial relations should look again. Learned societies, charitable foundations and the like – the same applies. Many govern- ments in recent years have created ‘hived off’ agencies which make things (e.g., maps), publish things (e.g., guidebooks), and do things (e.g., maintain roads and run railway stations), and these are ‘outfits’ which, shall we say, operate in something like a profit-and-loss environ- ment and reporting structure, even sometimes to taxpayer-shareholders. I mention this because the word ‘taxpayer’ arises in the discussion below, and there are considerable anti-commer- cial sentiments in (what remains of) the public sector and academia generally (however it is organised). Being anti- commercial is fine, maybe noble; but being in a zone of illusion is dangerous. I find it intriguing that the previously commonplace and banal concept ‘price’ has – in propaganda-speak – suddenly become a ‘paywall’. WHAT IS THE ‘OPEN’ IN OPEN ACCESS? The overview above has sketched out a very broad picture of where ‘we’ (globally) are, and has left aside any instant critique or defence relating to the various interest- ing boundary lines involved: public/pri- vate, academic/commercial, production/ consumption, author/reader, gratis/priced and the like. Continuing the binary theme, I contend that OA as a political project has two very broad strands: ● An anarchist/libertarian argument for freedom to access and use ‘information’ independent of authorial property rights, particularly as licensed to publishers; this ‘free’ access is made visible in var- ious internet repository arrangements where there is no charge per view or restriction on use. ● A public accountability argument relat- ing to academic research and taxpayer funding for universities and the like, but ‘If you want to self- publish and self-market, with or without payment or profit, then go right ahead’. terrell carver european political science: 15 2016 185 also to taxpayer funding of libraries which make major subscription pay- ments to publishers, particularly for research journals. There is no reason why these political projects cannot exist (or co-exist) most anywhere. However, in relation to the second strand, there are very particular circumstances that many UK-based aca- demics see as a major change, and some perceive as a threat or inversely as an opportunity. Hence it is important to rea- lise that the situation of academics – and their perceptions as well as those of their managers and policy-setters – will vary, and outside the UK will very likely be at variance with UK fears and hopes. The first – anarchist/libertarian – pro- ject arises as out-of-copyright materials are made accessible gratis for those with internet connections, hardware, software, skills and interests. It is of course an interesting question how this productive activity is funded, who is paying, and where this enterprise is headed. Your ‘free’ access will probably be subject to advertising pop-ups, commercial infor- mation aggregation and no doubt security surveillance of certain kinds, legal, consti- tutional or otherwise. It is important to note, however, that there is a something of an illusion at work here – perhaps ‘the illusion of the epoch’, as Marx and Engels put it – that the internet is a ‘realm of freedom’ where you get what you want as a consumer for nothing, but then leave aside the more difficult questions – often deliberately obscured – as to who is pay- ing for the services and products involved in the first place. The second – public accountability/tax- payer funding – is somewhat more com- plicated and less easily generalisable. But it relies on even more powerful ideological sloganising (rather than just an illusion that the internet tells us that goods and services are produced for free and con- sumed for free – which as a reality even Marx and Engels thought was some way off). Amidst the commissioned reports, ministerial statements, press releases, consultative documents, parlia- mentary testimony and the like, I discern the following three contentions: 1. Information should be freely available. 2. Publishers make too much profit. 3. Taxpayers should not pay twice. Politicians can be forgiven (well perhaps, anyway it’s their job) for sloganising with sound-bytes and half-truths, headline- grabbers and crowd-pleasers, crypto-prin- ciples and claims that do not stand up to scrutiny and reason. However, academics – and their manager and paymasters – possibly have less excuse. I take these three slogans in turn: SLOGAN 1. INFORMATION SHOULD BE FREELY AVAILABLE Information (whatever that is) is some- times available gratis (e.g., ‘Jesus saves’, free newspapers, flysheets, advertising ‘alerts’ etc.), but – as explained at the outset – there are costs associated with its production. Cost of production, of course, is not a sure guide to value – whether of exchange or use (another nod to Marx). Nonetheless goods and services may arrive ‘freely’, but their production is anything but. The perception that produc- tion happens ‘freely’ is related to the illusion of the internet, mentioned above. Often debates in this area evolve into ‘geeky’, alphabetical disputations on licensing issues (CC-BY-NC-ND) and ‘Creative Commons’ use and abuse, aspiration and enforcement. While undoubtedly interesting and germane, this kind of discussion turns on accepting OA premises in the first place, and buying into the idea that content-producers just make things and ‘put them up’ for nothing, and that’s that. european political science: 15 2016 open access186 SLOGAN 2. PUBLISHERS MAKE TOO MUCH PROFIT Excessive profit and tax avoidance are both in the news, the latter on a rather firmer legal and political basis than the former, but even so, there are issues. Quite how much profit is excessive, though, is hard to deter- mine against even political criteria. Most parties defend commercial success as essential to national interests in the first instance, or at least economic success is acknowledged as a hugely important resi- dual. Market regulation works – as well as it does – against the tendency of markets to monopoly, so, in so far as ‘excessive’ profits arise from an unwarranted monopoly, then we know what to do (or say we do). Other- wise profits ‘go to town’ unless and until competitors challenge this position and consumers get a better deal (or that’s the theory, anyway). Starbucks was not allowed to monopolise espresso coffee, and competitors arose. McDonald’s never monopolised hamburgers – so end of story. So where are the excessive profits in publishing, and who has an unwarranted monopoly? Academic journal publishers have proliferated journals, and publishers themselves have proliferated. Global mar- kets for research journals have expanded even more. Possibly there is a problem with monopoly here, but it is only one that academic ‘journal ranking’ creates (and for which certain publishers are doubtless grateful). But then academics have only themselves to blame. Journal publishing is an international industry, and many of its product-provi- ders work for them for nothing (or nearly nothing), for example, authors, reviewers, editors (who might get expenses), and the like. We academics could demand pay- ment and withdraw our labour if payment were not forthcoming. We could put the publishers out of business (or that sector of their business, anyway), and do all the production work ourselves! Well, fine, though it will be a lot of extra work for no pay at all. As with any competitive, commercial and commoditised set of arrangements, there is a huge amount of room for negotiation and ‘wiggling’ in all directions, particularly push-pull. That is what markets (more or less) allow. But then we are back to the difficulties and hazards of self-publishing. What is largely missing from this situa- tion so far is consumer-resistance, for example, from those who manage library budgets and simply pay up what publish- ers ask. Thus they fail to negotiate (or fail to negotiate hard enough) with suppliers to get a better deal. Suppliers understand this language; that is what sales depart- ments do. But – to my knowledge – not that many librarians, individually or col- lectively, ring them up and threaten to cancel. Instead, they go back to univer- sity and similar institutional managers with cuts and cancellations. There are of course notable exceptions to this, and some good results, including joint action to get economies of scale (and clout). But anecdotally I am also told that within academic institutions the monitoring of duplicate and inefficient subscription pat- terns can leave much to be desired. Aca- demics may of course be fairly happy with this, given that they want secure (if dimin- ishing) supplies, or demand trade-off cuts elsewhere from others – or possibly engage in income generation through entrepreneurial activities (which takes us into other areas). Perhaps the major international journal publishers are exemplars of greedy capi- talist indifference to human needs and talents, and perhaps they should be taken down for that reason. But then if that is the project, I would respectfully ‘So where are the excessive profits in publishing, and who has an unwarranted monopoly?’ terrell carver european political science: 15 2016 187 suggest starting elsewhere (maybe arms dealers?). SLOGAN 3. TAXPAYERS SHOULD NOT PAY TWICE Taxpayers paying once or twice is the easiest illogicality to dispose of. Many citi- zens are not taxpayers. Many taxpayers pay for things they will never have access to, gratis or otherwise (e.g., nuclear weap- ons, defence installations, security agen- cies etc.). Many taxpayers pay for things that they might use, but never do (e.g., railways, airports, motorways etc.). Many taxpayers pay again for things they have paid for once already (e.g., railway jour- neys, national monument visits, road and bridge tolls etc.). Many taxpayers pay further taxes to use things that they have already been taxed for (e.g., airport usage taxes per flight). It is of course interesting – if tedious – to unpick the connec- tions between, say, UK taxation, univer- sity funding, academic teaching/research, journal subscriptions, research grants and the like. But let’s simply leave that aside as a conundrum. BACK IN THE UK Here is where the very particular mix of UK threats and opportunities kicks in. UK research, done by academics at uni- versities (and the like), is regularly assessed for ‘quality’, and the relevant agency has announced plans to require OA (in some form or other) as a condition of eligibility for peer-review of a ‘pub- lished’ item. This is hugely significant to UK-based academics and to their career- concerns (and to the similar concerns of their research managers). It is of zero concern to those outside this system. There are other national university sys- tems of research quality assessment operating in other countries, where so far the kind of stringency announced initially in the UK isn’t really taking off. It might, but it isn’t. In any case, the UK agency involved is backpedalling somewhat from its original position (and hence the politi- cal ambitions involved seem to be moder- ating, i.e., the minister has moved on). Possibly someone noticed that a blanket- restriction on what can be submitted for quality-assessment would diminish – rather than enhance – the reputation of the whole exercise within and outside the UK. If you are not surveying a sample of all ‘published’ research, but only a rather arbitrarily filtered slice of it, then the comprehensiveness of the whole exercise is cast into doubt. Moreover the UK research councils have announced a policy that OA (in some form) would be required in the ‘outputs’ of the research projects that they fund (and the funds are largely derived from public sources). And some private or charitable funders have for some time had similar requirements. Thus UK researchers can be hit both ways, via research quality assessment, and via con- ditions attached to grants that affect how and where their work is disseminated. Were the publishers upset by these moves? Oddly not. A requirement that articles from UK-based (or prospective UK-based) authors will only go into a journal, only to go out again gratis, seems to work against their subscription model. Why should university or other librarians pay a subscription for research informa- tion that anyone anywhere (academic, taxpayer or otherwise) can access gratis (given appropriate equipment and human capital)? Actually many publishers have had OA in place for years, and contrac- tually it was always a potential, anyway. If you license your work for a publisher to exploit (and protect), and they produce the intellectual product (at a cost to them), then if you want out of the deal, and wish to make the product available gratis to the world, make the publisher an offer. Or if you don’t like their price to buy european political science: 15 2016 open access188 the rights back, complain and say you’ll go elsewhere next time. Or don’t sign in the first place. If your funder requires OA in this way, then make sure you get it funded by them in your grant. And complain if they renege by cutting your budget. It may not be nice, but that’s how it works. Publishers were rather unworried because – in general – UK authors and income are significant, but not deter- mining for their business models. They sell journals all over the world, including a number of all-OA ones now. These all- OA journals do not have a free-produc- tion/free-consumption business model – no one does. For an OA journal (so- called) someone pays production costs (usually the author), so that you the consumer can access the content gratis. Moreover, publishers have responded to the OA-threat (really a publicity threat, rather than an economic threat) by mak- ing all kinds of content free-to-view – old content, special content, ancillary con- tent, database content – and they are constantly working on pricing, packages and global sales. Free offers/limited period, buy-one-get-one-free, whatever. And – for those who have followed this logic closely – since funded OA has come in the UK, publishers have had an oppor- tunity to collect twice for the same work! Journal cancellations are not cascading in because of OA in the UK; payments by authors, funders and universities (via the funding agency) are flowing into publish- ers’ coffers as well. Maybe this is unstable and unsustainable, but then so is every- thing (or nearly everything) in a competi- tive market situation. However, so far OA has produced a situation that benefits publishers, who are doing better than ever. A SPECTRE IS HAUNTING ACADEMIA In sum, what is threatening and shocking is not OA, even in the UK. What is threa- tening and shocking is the reaction in UK- academia to a plausible-sounding – but really not very important – ministerial ‘initiative’. Too many people in the UK were far too willing to jump on board a bureaucratically piloted ship, for the sheer joy of being on such an exciting cruise, advertised with such exciting slogans. However, two years on, even the propo- nents – both bureaucratic and overtly political – have turned the ship around somewhat, and in any case the party- streamers have wilted. More people in the UK should have kept their feet on the ground, and stood their ground, painful as it might have been at the time. The authoritarians have backed off, but prob- ably not because they encountered that much resistance. Probably they are find- ing other areas of interest … so watch out, UK academics! What is particular about the UK is the interlocking system of public university funding (and nearly all universities are ‘in the system’), and its susceptibility to ministerial initiatives and bureaucratic control by fiat. Sadly, complicity, gullibility and misplaced enthusiasm are probably everywhere. That is the spectre haunting global academia – not OA. Reference Working Group on Expanding Access. (2012) ‘Accessibility, sustainability, excellence: how to expand access to research publications: Report of the Working Group on Expanding Access’, 18 June 2012, available at: http://www.researchinfonet.org/wp-content/uploads/2012/06/Finch- Group-report-FINAL-VERSION.pdf, accessed 17 November 2014. terrell carver european political science: 15 2016 189 http://www.researchinfonet.org/wp-content/uploads/2012/06/Finch-Group-report-FINAL-VERSION.pdf http://www.researchinfonet.org/wp-content/uploads/2012/06/Finch-Group-report-FINAL-VERSION.pdf About the Author Terrell Carver is Professor of Political Theory at the University of Bristol, UK, and a Fellow of the Academy of Social Sciences, publishing widely on Marx, Engels and Marxism, and sex, gender and sexuality. He has held academic appointments in the UK since 1974 and served on the executive committees of the Political Studies Association of the UK and the International Political Science Association, where he is currently Vice-President for Europe. This work is licensed under a Creative Commons Attribution 3.0 Unported License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/ european political science: 15 2016 open access190 http://creativecommons.org/licenses/by/3.0/ open access: nothing much new (or very little, anyway) IN THE BEGINNING … WHAT IS THE ‘OPEN’ IN OPEN ACCESS? SLOGAN 1. INFORMATION SHOULD BE FREELY AVAILABLE SLOGAN 2. PUBLISHERS MAKE TOO MUCH PROFIT SLOGAN 3. TAXPAYERS SHOULD NOT PAY TWICE BACK IN THE UK A SPECTRE IS HAUNTING ACADEMIA Note References work_4kply5tgsnc3hnlybqw6mdzrxu ---- M any people skip over the fact that, from early April 1911 to late July 1912, Albert Einstein lived in Prague. “It was, after all, such a short time, and quite early in the physicist’s career,” Michael Gordin explains at the start of Einstein in Bohemia. Historians have variously dismissed those 16 months as an interlude, a sojourn and a detour. So did I — before I read this improbably good book. Multiple biographies of Einstein agree that the Prague period is notable for one main rea- son. Free of the heavy teaching load that had burdened him as an associate professor at the University of Zurich in Switzerland, he focused A fresh look at Einstein’s Prague period Michael Gordin’s elegant prose uses 16 months to build a panoramic view of a century. By Pedro Ferreira. on developing his general theory of relativity. It was in Prague that Einstein came up with the idea of gravitational lensing, the concept that the pull of stars, planets and other astronomi- cal objects would distort light rays. That idea — tool — is now central to modern astronomy, used to determine, for example, how much dark matter is hovering around clusters of gal- axies. Although Einstein had yet to conjure up a dynamical theory of space-time, it was his prediction of gravitational lensing that would demonstrate the theory’s chops in 1919, when physicist Arthur Eddington and his colleagues measured how light from stars in the Hyades cluster was deflected by the gravitational pull of the Sun during a solar eclipse. Personal impact At a personal level, gaining the position of professor of theoretical physics at the German University in Prague pushed Einstein into the senior echelons of academia. Just three years before, he had been a patent clerk in Bern. Interestingly, Gordin tells us, he was not the first person to be offered the job: first refusal went to one Gustav Jaumann at the German Technical University in Brno (who remembers him?), who turned it down. It was also in Prague that Einstein’s marriage to fellow physicist Mileva Marić began to fall apart. She was miserable there: snubbed as a Serbian and resentful at being dragged around for her husband’s career, then left sitting at home while he travelled elsewhere to give talks and collaborate. It was during a trip to Berlin that he began an affair with his cousin Elsa Löwenthal, who eventually became his second wife. But that is about it. Slim pickings on which to base a whole book, I feared. Yet Gordin does something ingenious. He uses Einstein as a MacGuffin, a device that propels the plot but has little significance to the story he wants to tell. He explodes the narrative out of what he calls the “spacetime interval” of 1911–12 to follow a host of figures who were involved with Einstein in Prague, in some cases very tangentially. In so doing, he careers through the history of ideas as well as the political Albert Einstein worked at a university in Prague in 1911–12. Einstein in Bohemia Michael D. Gordin Princeton Univ. Press (2020) H IS T O R Y A N D A R T C O L L E C T IO N /A L A M Y Nature | Vol 579 | 5 March 2020 | 23 Science in culture Books & arts © 2020 Springer Nature Limited. All rights reserved. The Incredible Journey of Plants Stefano Mancuso (transl. Gregory Conti) Other Press (2020) About 400 metres from ground zero in Hiroshima, a weeping willow and other plants regrew from their roots. Revered, they are labelled hibakujumoku, “trees that suffered an atomic explosion”, an elderly Japanese diplomat translates in flawless Italian for visiting plant neurobiologist Stefano Mancuso. Later, he confesses he is a hibakusha: he survived the strike because his classroom was protected by a curtain of trees. Such anecdotes enliven Mancuso’s quirky little global history, which argues that plants “are more sensitive than animals”. The Story of More Hope Jahren Vintage (2020) In 2009, palaeobiologist Hope Jahren was required to teach climate change. Initially reluctant, she soon conceived a vocation. Her compelling book uses statistics brilliantly to provoke self-examination. In sections on ‘Life’, ‘Food’, ‘Energy’ and ‘Earth’, it illuminates subjects from population growth to melting glaciers. If the whole planet consumed resources on the US scale, carbon dioxide emissions would be more than four times higher, she observes: “Using less and sharing more is the biggest challenge our generation will ever face.” Footprints: In Search of Future Fossils David Farrier Farrar, Straus and Giroux (2020) Fossil footprints unmasked by a 2013 storm on the English coast revealed that hominins walked beside an estuary 850,000 years ago. Although quickly erased by the tide, they inspired David Farrier to consider modern civilization’s future footprints, including Neil Armstrong’s marks on the Moon and the nuclear footprint: a geological repository for Finland’s spent fuel. This is designed to be forgotten — unlike its US equivalent, which proposes to use warning signs modelled on Edvard Munch’s 1893 painting The Scream. The Future of Brain Repair Jack Price MIT Press (2020) In 1996, neurobiologist Jack Price, then at a major pharmaceutical company, was invited to fund academic research into stem-cell therapies. He declined. Now an academic himself, he is more hopeful. In 2006, Shinya Yamanaka discovered how to make ‘pluripotent’ stem cells, enabling brain-like tissue to be generated in a dish — “albeit small, misshapen and underdeveloped”, as Price notes in his clear, honest but intellectually challenging account. Today, several therapies have entered clinical trials. But how to make them affordable? Radical Uncertainty John Kay and Mervyn King Bridge Street (2020) When Christopher Columbus sought a westerly route to the Indies, “whatever counted as cost–benefit analysis in the Spanish court took no account of the possibility of a New World”, say economists John Kay and Mervyn King. They refreshingly criticize their discipline for not recognizing that its use of ‘risk’, ‘uncertainty’ and ‘rationality’ doesn’t match that of lay people. Odd, then, that their far-ranging book on “radical uncertainty” mentions Max Planck’s dalliance with economics but not Werner Heisenberg’s uncertainty principle. Andrew Robinson turmoil of Bohemia (now part of the Czech Republic) during most of the twentieth century, touching on physics, philosophy, nationhood, anti-Semitism and the rise of Prague as a centre of intellectual life. There are quirky observations, almost worthy of playwright Tom Stoppard. For example, Einstein and writer Franz Kafka prob- ably met at a 1911 cultural soirée in the house of Berta Fanta, a “philosophically ambitious” socialite who held a salon above her husband’s pharmacy in Prague’s Old Town Square. Social circle But what really grips are the people. Take Oskar Kraus, a philosopher at the German University. Originally trained in law, he took against Einstein, writing countless articles in philosophy journals unpicking what he saw as egregious internal inconsistencies in rel- ativity. His writing and stance foreshadowed the anti-relativity strand of the Deutsche Physik movement, an eviscerating force in German academia during the rise of the Third Reich. Kraus, who had been born into a Jewish family but converted to Protestantism, was arrested by the Gestapo and ultimately fled to Oxford, UK. Inevitably, Gordin takes in Ernst Mach, who had been in a post similar to Einstein’s at the German University’s forerunner from 1867 to 1895. Mach had been “the most successful physicist in the university’s history” and played an important role as rector for part of his ten- ure. But, like Einstein, he had been the second choice for the post. Mach’s ideas shaped the work of important relativists after Einstein, such as Dennis Sciama and Robert Dicke. Another pen portrait is of Einstein’s successor in the post, physicist and philoso- pher Philipp Frank. His journey through the turbulent Prague of the 1930s serves as spot- light on a place battered by historical forces. During the late 1920s and early 1930s, Frank was part of the Vienna Circle, a hugely influen- tial group of scientists and philosophers that also included philosopher Rudolf Carnap and mathematician Kurt Gödel. In Prague, Frank did much to carry the flame of both Einstein and Mach’s ideas through books and journal articles, publicly sparring with Kraus when- ever necessary. In 1938, he had to flee to the United States, where he ended up at Harvard University in Cambridge, Massachusetts, and wrote one of Einstein’s first and most notable biographies. This is a panoramic view of twentieth-century Bohemia, with a sprinkling of Einstein. But what really carries it through is the beauty and force of Gordin’s prose. Pedro Ferreira is professor of astrophysics at the University of Oxford, UK, and author of The Perfect Theory. e-mail: pedro.ferreira@physics.ox.ac.uk 24 | Nature | Vol 579 | 5 March 2020 Books & arts Books in brief © 2020 Springer Nature Limited. All rights reserved. work_4nvwqpya3fgnfcatzd2ctzu6ee ---- Microsoft Word - 10th Jan fictional Drawings.doc O'Donnell, Lucy (2018) The magnified glass of liberation: A review of fictional drawings. Drawing, research, theory, practice, 3 (1). pp. 47-62. Downloaded from: http://ray.yorksj.ac.uk/id/eprint/2940/ The version presented here may differ from the published version or version of record. If you intend to cite from the work you are advised to consult the publisher's version: https://doi.org/10.1386/drtp.3.1.47_1 Research at York St John (RaY) is an institutional repository. It supports the principles of open access by making the research outputs of the University available in digital form. Copyright of the items stored in RaY reside with the authors and/or other copyright owners. Users may access full text items free of charge, and may download a copy for private study or non-commercial research. For further reuse terms, see licence terms governing individual outputs. Institutional Repository Policy Statement RaY Research at the University of York St John For more information please contact RaY at ray@yorksj.ac.uk https://www.yorksj.ac.uk/ils/repository-policies/ mailto:ray@yorksj.ac.uk 1 Abstract: The article uses an inactive creative period to consider drawing as a type of fiction. The writing style adheres to academic conventions, however the author’s autobiographical experiences and wonderings are critical in exploring drawings fictions. It revisits making and thinking to explore drawing and philosophizing as speculative commutable passages of exploration and inquiry. The article chronicles the preparation of fictional drawings for a Fictional Museum of Drawing created by Phil Sawdon. This article reworks Sawdons site of fictional drawing, advocating drawings fictions as twofold, as rooted in foresight where predisposed thinking is navigated and anticipation reigns. The other recognition of fiction focuses upon the material illusions of thought. It plays on the autobiographical disposition of drawing/writing redrafting spatial origination of words to become diverse and contradictory graphics of language that displace the blank page. The fictions of the drawings/writings reviewed in the paper pressure syntactical devices and worded conventions, where the works reorganize conventions from both drawing and writing using illusion and paradox to unsteady their material. 2 The magnified glass of liberation: A review of fictional drawings Lucy O’Donnell York St John University This paper reflects upon the paradoxical process of making drawings for Phil Sawdon’s ‘Fictional Museum of Drawing’ published by Fukt Magazine 13 (2014).1 It chronicles the creation of fictional drawings for a fictional museum to foreground drawings material and speculative activities that perform on the parameters of fiction. The drawings employ words and can be thought of as hybrid drawings/writings. This brings debates from drawing/writing to the project, particularly with regard to revisiting material possibilities. The dilemma of making drawings for a space that does not exist is used to reflect upon how predisposed thinking is navigated by drawing by interweaving foresight and hindsight. The writing style of this article adheres to academic conventions, however the voice is heard wondering and could, at times, be thought of as poetic and playful, thereby teasing out the fictions embedded in the project. This deliberate reference to the author recalls a period of difficulty in making drawings and its emotional effects. This method crucially draws on/out the parameters of fiction embedded in both processes of thinking and making. It makes links between the methods of drawings and philosophizing as critical modes of thought, exploration, and expression to propose that material thinking and speculative hesitations are types of fiction. The accounts of making fictional drawings for a fictional museum are presented in this paper through a fundamentally contradictory practice that privileges fiction. This acknowledges Alan Badiou’s (2006) notion of drawing as a constructive deconstruction in order to 1 The ‘Fictional Museum of Drawing’ is ongoing, Phil Sawdon describes himself as keeper, and his undertakings can be viewed here http://philsawdon.tumblr.com. Accessed November 2016. His ‘Fictional Museum of Drawing’ can be understood as a repository of articles and a conceptual space for much of his creative and research work and an account was published by Fukt Magazine in 2014 where words, readymade propositions, parlance, bricolage and other marks join together. Although their composition utilized the organizational features of Microsoft Word, it also demonstrated/signified/employed a break from linear syntactical modes. Here the drawing is presented within the words, their meaning and placement composed and interwoven with other markings. The term Fictional Museum of Drawing is used in this article to represent a fictional space, one that does not physically exist. 3 understand its methods, which are bound between foresight and hindsight, become an ultimately speculative act. This article goes on to propose possibilities for harvesting drawings, review particular works (The Prison Drawing Project, Travelling, flickering and re- framing and This page has intentionally been left blank, parts 1 & 2) and concludes with a summary of how such an absurd project reopened the irregular territories of drawing. Procrastination Research Organization: anxious and unknown This week the PRO (Procrastination Research Organization) postponed the monthly meeting in order for its members to mull over other significances. The PRO is an invented group, used here to make reference to the pandemic that affects academics, where forecasting obscures research production. The preparations for my show at the ‘Fictional Museum of Drawing’ were ever increasingly inactive, so for me, this took precedence. There were two pressing concerns, both needing attention. Firstly, it was important for the practice to reflect and convey its critical concerns: to perform in the parameters of fiction. The drawings proposed for the ‘Fictional Museum of Drawing’ aspired to be equipped with imagined, fictitious, story bound and false propositions; they were to play amongst one of contemporary drawings’ frequent preoccupations: expanded fields and the pleasures of illusion. These fictional drawings were to defer material, physical and actual junk, softening the pressures of site, composition, reading and interpretation. Preparing for the show was proving complex. The drawings often remained in my head and wouldn’t come out; they were hosted by aspirations. The drawings were afraid of the white paper, anxious of the unknown and indefinite, frigid and afraid of being wrong, afraid of laying bare witness for others to make judgment. But paradoxically, I wondered if they were not tied by materiality but, instead, hosted by aspirations, could these be the most glorious fictional drawings of them all? These drawings nestle naked as they day they were not born, miscarriages; material of conception that stay so close to the mother it becomes synonymous with her. Ideas of matter and mattering had been consistent in my reflections of drawing. Catherine de Zegher (2006) makes associations between drawing gestures and the bond between mother and child by identifying particular parallels between the extended arm moving 4 away from the body as an equivalent behavior made by children when reaching out for a departing mother: ‘In the act of drawing, the extended arm and hand away from the bodily axis seems to correspond to the very gesture involved in the first separation (and exploration) where the child reaches out to the departing mother[…] Informed at once by rupture and reciprocity, drawing constitutes a space of relation in which the thrown-out gesture conjures up a trace seemingly tied to this movement used to the retrieve the thought that has been cast out’. (de Zegher 2006: 214-15) These thoughts around the relationships between child and mother resonate with experiences of personal loss, where the body unexpectedly casts away a pregnancy. Here the ‘thrown out gesture’ is the first and final separation; the casting away is absolute and the thrown out gesture is permanently contained, never to retrieve thought or aspirations. My experience of listening to a doctor change their language from baby to ‘material of conception’, has led me to return to the phrase in order to also deliberate drawings’ fictions. Here, in a singular moment the understanding of my unborn child had broken down. This become a catalyst for me to revisit the absurdity of syntactical devices and worded conventions. I was influenced by this language paradox, where the autobiographical investment in drawing was to override permanence and revisit the relationship between making and thinking. The miscarried pregnancies wilted ambitions and the drawings lingered in misty aspirations. This indistinct place muted any warning bells that ring to alert caution of the perils of predisposed thinking/making activities, where actualizing is ultimately delayed. It seemed irregular drawing territories were being unveiled, where act lingers in ambition, seizing upon Alan Badiou’s ‘constructed deconstruction’. Through fraternizing with foresight and hindsight, the collaboration between the known and the cautious places in between became a reflective space that could project knowledge onto a foresight suspended by anticipation, sagacity, and shrewdness. This openness gave the drawings permission to enter unpatrolled terrains, where rules are inadequate and anticipation reigns. This undefended drawings had no resistance to marksmen or mutiny; without the predisposed thinking it was an unprotected space 5 exposed to the elements once again, where line, tone, texture, form/mass, colour and perspective can be reconsidered. Harvesting the false: Preparing for the show These drawings for the show were not necessarily ‘drawn’ and are, instead, better described as ‘harvested’, as this gives precedence to condition and preparation, where a formula is reliable enough to reap crops. So in initial perpetrations for the show I looked back to bubbling thoughts and discarded possibilities bound in sketchbooks. These trace back and forth from idea to execution, from head to hand, from sound to site, from pondering to bemused (and more bemused); marks, ideas, propositions and notes meddled together posing as paths to follow, possibilizing upon, opening up the maybes, and giving respiratory relief to the taxidermy of fixed needs. In a bid to examine dialogues between theory and practice Nicolas Davy (2006) described the dangers of philosophy as taxidermy: where nothing can escape alive. This mode of thinking is bound up in its course of scrutiny, which prejudices its direction and leaves it suspended in its material articulation. The graphic works on paper lay bare the seen and propose the unseen, which is narrated by the gesture of the hand: its speed and pressure recounting the process of marking thought. My drawing practice often used words, letters and punctuations in fragments in order to wonder about drawings syntax. By bringing drawing/writing together, a constructed deconstruction of both took place, questioning foundations of how we think and communicate. Recently for ‘The Prison Drawing Project’ I focused upon the parallel roles of the paper drawing support and the enclosed prison cell as jointly restricted spaces where activities are conscious of their boundaries. This project was held at The Old Borough of Scarborough Jail in February 2016, and the drawings were exhibited within the individual cells. This restricted space allowed a certain type of curatorial approach, where the boundaries of the space and the methods, materials and subjects employed by the artists were all compounded in order to interrogate contemporary drawing practices as paradoxically open-ended. The interrogation of these borders outline drawings’ critical edges as places ‘with play’, which licenses constant change. Here the drawing/writing inscriptions and their wondering navigation(s) become the focus of the work by repeatedly redrafting the pages of my PhD thesis. The paper became a type of constituent where thoughts are caught, overlaid and replayed, making 6 reference to the confined spaces of the page and cell as a limited place to play out thinking. This redrafting process sustained ambiguity by creating a blended mass of information that obliterated the typed text and drawings; instead drawing out an alternative marked semiosis that was performed in the cell as rephrased gestures (see figures 1–5). Molded by the process, these paper worlds allowed opportunities to reveal themselves where possibilities to unfold and the syntax, or fiction, of the drawing evolves within the doing; seizing the descriptive currency of the material, the word play creates a knowing distance between conventional syntactical devices and becomes open-ended and speculative. The drawings for the ‘Fictional Museum of Drawing’ were ideal at adopting a speculative sovereignty. They had to be prepared and harvested in a sprit that reveled in the theater of illusion, mystery and, of course, ambiguity I thought of Avis Newman in 2003 positioning drawing as a communication device beyond or before language. For the drawings in the ‘Fictional Museum’ these ideas redirected any primitive critique, and, instead, speculated upon the embryonic and emergent fictions. Possibilities unfolded within their acts and speaking took forms unbound to syntactical structures; like the Re-Aligning Vision of León Ferrari’s drawings, or silent handwritten words that tell things that word’s cannot say, the drawings evolved in worlds particular to themselves. But how do you harvest a drawing that evolves within the doing, without ‘doing’ it? The drawings for the show needed to perform in the parameters of fiction, and I wondered about the elasticity of this position. Could all drawing be fictitious? When a pencil comes in contact with paper, the gestures generate marks onto a paper surface, creating illusions that reference something other (form, subject, gesture, or manner). Our principles of conjuring up volume, form, matter, and subject are manufactured and manipulated. 7 Figure 1: Drawing Vignettes. 2016 8 Figure 2: Drawing Vignettes. 2016 9 Figure 3: Drawing Vignettes. 2016 10 Figure 4: Drawing Vignettes. 2016 11 Figure 5: Drawing Vignettes. 2016 12 The speculative fictional drawings were taking place ubiquitously as I moved from place to place between work, studio, and home playing with words in my thoughts and on paper. At the annual Society of Artistic Research 2016 conference, I listened to Alva Noë proposing philosophy as a reorganizational practice that needed to ‘fuck things up’ in order to question and review. This proposition intensified my word play as mirroring reflections of uncertainty that could displace marking activities and reflect thought as dwelling in speculation. This speculation was unsteady or flickering, as it was neither ‘on nor off’ or ‘thing or thought’ in between material ‘junk’ and in transit. Alan Badiou (2006) describes drawing as a fragile ‘movable reciprocity between existence and inexistence’. Here drawing is a place that dis(places) all things in it, likened to performance or happenings, with ‘vanishing succession of gestures, pictures and voices’, as a ‘constructive deconstruction’ that is ‘more real’ than the stimuli. Drawing as a description without place, certainly appeared to ‘fuck things up’ in the sprit of Alva Noë. Whilst on my train commute home my body in its immobile mobility struck cords with Michel de Certeau in his Practices of Everyday Life (1998) where with nothing to do one is in a state of reason. And this static speculative experience of the world, where the sensation of static mobility is heightened, became my place to draw. The expanded ‘composition’ was ubiquitous; where, as the commuter, I took ‘thoughtful workouts’ gazing out of the window speculating about unfeasible drawings. My journeys from A to B, pause, stop and move through fleeting territories: jointly commuting and speculating. This displacement within space heightened these embodied senses and I wondered if drawing with words were like silent stories, souvenirs of the commuter. The initial drawing travelling, flickering and reframing combined compositional fictions with the imaginary, fuse the peripatetic thinking making being wondering (See Fig 6, embedded in the text page). 13 travelling, flickering and re- framing ‘Fucking it up’ with Alva Noë: employing his notion of philosophy as a reorganizational practice to make these notes and keynotes from ‘WRITING’ The SAR International Conference of Writing, 2016. I’m training (on a train) […] (budumbudum) exercising & traveling (budumbudum) tacking a thoughtful workout (budumbudum) work ings out (and in) (and out)… (budumbudum) flickering drawing into writing . . . (budumbudum) flickering on off over back on off over back on off over back (on a train) (budumbudum) flickering… (and travelling) between drawing & writing (on a train) words: wording words telling of language denoting self … Henri Michaux drawing on in over (through) self and language or self/language (drawing & writing) (in out) (budumbudum) (in out) (budumbudum) (in and out) (budumbudum) (in/out) (budumbudum) Hit …the ‘picture’ and the self. (i propose this) hard. Narrative or (i propose me) Typing to proposition peek into ice cream vans that play songs of flat Dutch spaces and opened out spaces, postulating. Seeing drawing thinking writing (seeing/drawing/thinking/writing) Dwelling in out over Flickering on Flickering The trains training (and Kate Liston) Flickering Whose body builders erect Dasein & mnemonic symbols Flickering fused with protein supplement Casein Flickering Flickering f I’m Flickering l training Flickering i […] Flickering c exercising & traveling Flickering k as a thoughtful workout Flickering e work ings out (and in) (and out)… Flickering r 14 Figure 6: Travelling, Flickering and Reframing 2016. Travelling, flickering and reframing played with words as drawing materials and displaced conventional written compositions. By using the words as drawing materials, it was important to alter any stabilized meaning and to open up syntactical structures. The authority, or trust, we invest in words is probably upheld by a conviction to a stabilized communicative system underpinned by pre-determined meaning. However, this malfunctions within The Oxford Dictionary of Modern Slang, which confirms the contrary: language evolves and its denotation is recycled. A conversation I once had with John Court rang in my mind when he asserted, ‘you can’t trust words’.2 Revisiting and reposting words and notations reclaimed conventions and alternative fictions for the line and paragraph. The possible play of conventions embedded within the written order of lines drew thoughts back to poet bpNichol, whose practice is arguably underpinned by an appreciation of and fascination with lines of all types. Paul Dutton describes this as poetic play as lines, prose lines, narrative lines, plot lines, typed lines and lines of type, voice lines, drawn lines, solid lines, broken lines, train lines, and all the fine lines of and in communication, especially lines of questing, and lines of thought. 3 This preoccupation emerged strongly in bpNichol’s work, ‘Of Lines: Some Drawings’, featuring thirteen textured pages, each with a single silver line drawing, and underlined with titles such as ‘ Line #1’, ‘Drawing of Line #1’, ‘ Line #4(drawn whilst thinking of previous lines)’, and ‘Line Drawn as Response To An Inner Pressure to Drawn Another Line While Resisting The Urge To Call it Line#5’ (1981). When drawing with words, the ‘silent image’ is challenged and the silent picture of picture poesies is liberated. Equally, the conventions of speaking, silence, interpretation, and subject are all unsteadied. In Signs (1964), Merleau-Ponty suggests language as partly silent, as it does not directly voice an original ‘thing’. This emphasizes the allusive and oblique characteristics of language, and instead Merleau- Ponty advocates meaning lying in the movement of speech with its embodied gestures, silences, and responses created by location and acts. Drawing with words 2 John Court discussed his performance practice when he was visiting speaker at York St John University on 28th November 2016. His output includes performance, sculpture and video and he considers his work to be fundamentally concerned with drawing, in that drawing connects the elements of line, movement, space and time. See http://www.johncourtnow.com Accessed October 2016 3 See http://www.thing.net/~grist/ld/DTTN-BPV.HTM. Accessed July 2014 15 removes the stability of worded meaning redirecting the possibilities of ‘subject’ once suspended in its worded format. The reorganization jointly displaces expectations of the letters, page, subject, and certainty and so instead, words utilized as material for drawing can speculate and possibilize alternative fictions of both the paper, page, and its subjects. In 2013 The Drawing Room, London and The Drawing Center, New York curated Drawing Language. These works expose the union of drawing/writing as a mode to evoke multiple meanings by separating language from a linear narrative, breaking the presentation of words and phrases, incorporating multiple and contradictory graphic language forms, and creating forms from phonetic words and expressions. The drawings for the ‘Fictional Museum of Drawing’ had to be prepared and harvested in a spirit that reveled in the theater of illusion, mystery and, of course, ambiguity.4 It was here in the theater of illusion the sign and signified, Perian symbols and the indexical could be dispersed through new and irregular territories created within the unfolding drawing. In these territories, the paper margins regenerate fixed syntactical constructions, where the untrustworthy word deviates from structured customs conjuring illusion and paradox and becoming fiction drawing. I enjoyed words ‘untrustworthy nature’ and reflected upon their displacement while making This page has intentionally been left blank (part 1) 4 Phil Sawdons: A Drawing Parlay (2011) accounts for ‘The Fictional Museum of Drawing’: ‘The accumulative and ekphrastic guide to a fallacious building: A heuristic architecture of found words … readymade propositions, parlance and bricolage for no such place in the middle, the furthest place from fixed points of view.’ http://www.soanyway.org.uk/philsawdondrawingparlay.htm Accessed November 2016 16 This page has intentionally been left blank 17 Figure 7: This page has intentionally been left blank (part 1) 2017. Paradoxically the words inhabit the white page comforting the possible anxiety of its blankness. This work magnified the fictions of the page, inhabiting a halfway house, where the words are asked to inform the reader of absent words inciting absurd tensions. This page has intentionally been left blank (part 2) followed on from part 1. Here I scanned part 1 as a Jpeg and, by doing so, reframed and reinserted the boundary back onto the page. Here the size of the text was reduced and a thin gray line ran down the right hand side of the work subtly making reference to the edge of the paper. Figure 8: This page has intentionally been left blank (part 2). 2017 18 In these drawings, the blank page is a provocation to disturb the interplay between hindsight and foresight. The whiteness and the words heightened the anxiety of possibilities creating a momentum of possibilities and fictions. The gaps magnify the placement and displacement of subject and are crucial for fictional drawings. For Merleau-Ponty, worded meaning equally lies in what is unsaid, and the gaps between the words. These occurrences pose tensions for both speakers and listeners, while reinforcing the reliance of language upon its placement and displacement. The process of encountering the blank paper directs attention to both the boundary and the void: the space which is yet to be actualized. Jose Rabassa (1993) and Yves Bonnefoy (1994) identify opportunities to build space in the blank paper. Rabassa reflects upon the journal of Christopher Columbus, identifying parallels between writing/drawing and navigation, as the pen navigates the ‘fiction’ of the blank page the writer/explorer claims ownership of text and territory. The ‘fiction’ of the blank page suggests it already has chronicles, which leads to the anticipation of making discoveries by entering it. ‘…the white page is the unknowing which surpasses his ability to know…venturing into that white-ness and discovering there the precarity of all that has been acquired, the vanity of wants, and thus drawing near to that reality-unity that language robs us of. In this way, the drawing, the ‘great’ drawing, will be poetry’. Bonnefoy (1994: 15) The poetry of drawing breaks the whiteness, invites precarity, and its fictions can jointly construct and deconstruct, as Alan Badiou describes the fragile ‘movable reciprocity between existence and inexistence’. The paper support and its conventional whiteness becomes a place to wonder, as much as the unfolding activities that occupy it. The blank sheet of paper is a field for projection, for discovery and innovation. This concept forms part of a discussion between Avis Newman and Catherine de Zegher, where the blank sheet is described as ‘an undifferentiated space’ and ‘the entity of possibility’ (2003: 247). There is also a described and felt fear connected with this space, related by Bonnefoy (1994: 15) as an ‘unknowing’. And here Newman talks of the white page as a place of action: ‘ ...the fascination and the fear of the white page is the site in which one enacts differentiation as soon as a mark or sign is made It changes 19 the non-ness and establishes a place of action. As soon as that act occurs the paper becomes something’ Newman (2003: 247) Conclusion: Fictional Drawing A method to unsteady material junk The drawings for the ‘Fictional Museum of Drawing’ enjoyed the possibilities of playing in illusion and contradiction. The inactivities or fictions of making reconsidered words and their paper support become plausible tools that enable speculation to be seized as a method in conjuring illusion and paradox. Here, material conventions assertively promotes unknowing in a bid to allow alternative possibilities unfold. New Materialism, according to Stacy Alaimo and Susan Hekman (2008), stresses the importance of a review of language structures to reframe the ontological translation of experiences. Language structures are designated as a means to apprehend the ontological without constituting it. Matter is analytical currency for ‘reorganizing’ ontological and phenomenological experiences and borrowing notions from New Materialism where the body as a site of mattering, rather than matter, associates the becoming, interplay, and critical dialogue between foresight and hindsight. Placing and displacing are critical to fictional drawings where poetic freedom and flexible interpretation need speculative investment. These poetics permit the reframing of words into alternative spatial organizations legitimatizing open- ended spaces for graphic thoughts to dwell. Once removed from a dictionary, words are movable raw materials, unstable, untrustworthy and become something unexpected when time and place repositions them. The word play of fictional drawing opens irregular territories by breaking borders, operating in margins, and displacing activities and material; it becomes multiple or contradictory graphics of language. Here in the ‘Fictional Museum of Drawing’ speculation is associated with fiction through the supposed, and the imagined is conjured up from prospect and possibilizing. The employment of speculation as principal method reorganizes the spaces of thinking/drawing through revisiting their conventions and extending any dependence upon assumed material processes. This gives license to transient unstable activities that are so deeply embedded in speculation; their fiction can use the blanks and gaps to override conventional construction methods. The notion of drawing as a 20 constructive deconstruction can be related to the paper’s nothingness, which is apprehended by its boundary edges that pose anticipation. This is where Alva Noë’s philosophy as a reorganizational practice sets the metronome ticking between foresight and hindsight, unsteadying material junk to assume poetic wonder for drawing/writing within the ‘Fictional Museum of Drawing’. These works are driven by wonder to revisit what is known and assumed, where by avoiding material limits agreed, assumed rules can be broken and reshaped.5 The fictions of drawing are twofold: the first rooted in foresight where anticipation overshadows, the other performs in illusion where the communication of thought is material. Drawings’ analytical agency as a conduit of thought is probably conceded within its material, and for the fictional drawings the physical stuff can hover between what we know and possiblize something other. This interaction with physical ‘stuff’ enabled this article to review of language structures appraising material by making stuff matter. By drawing with words, or making hybrid drawing/writings, the language structures of each are by default, deconstructed through the activity of analysis. The doing of drawing becomes a thoughtful workout, where the marking out unites words and speculations carry on independent of material and within a speculative state. This revisited the routine of drawing as a way of thinking that could become freed from material, rerouted through speculation and uncertainty. The periods of not making or the gaps, the spaces between, became opportunity to revisit possibilities, reorganize, and deconstruct in order to construct a new. These gaps are home to anxieties and 5 The blank space, its void, erasure of ‘stuff’ or bareness all point back to the subject of nothing, where construction methods or subjects utilize the possibilities of absence or ‘nothing’ playing into ideas of something. Examples of these undoubtedly include Robert Rauschenberg’s erased De Kooning drawing, or his White paintings. Tom Friedman’s ‘Erased Playboy’ (1992) makes a nod to the erased De Kooning, re-questioning the efficacy of absence as an artistic trope. Other noteworthy examples that question the drawn, written or space of the page include, Gianni Motti's invisible ink drawings (1989): drawings made with invisible ink, visible only for a brief instant before vanishing. David Shrigley’s (2002) ‘Then There is Something’ from Human Achievement, whose hand-written words notate nothing by repeating the words ‘there is nothing’ down the page, which is interrupted by then there is something for a brief moment, then there is nothing again. Or ‘This Book is Intentionally Blank’, exhibited at the ‘Nothing’ exhibition (2001) at Cameraworks Gallery, made from recycled National Curriculum paper collected after it became defunct in 1989. Over 4 tons was first exhibited as waste, then later recycled and turned into white paper that was returned to the schools as blank drawing-paper; these politicized white pages make way for the new. An empty volume called ‘The Nothing Book’, published in 1974 & 1976 acts as an invitation to write your own book, posing the possibility as open that it can be whatever we want it to be. ‘The Book of Nothing’ (2000) by mathematician and cosmologist, John Barrow, drew from mathematics, theology, philosophy, literature, particle physics, and cosmology to explore our fascination and imagination around vacuity, or the absence of matter. 21 discoveries where drawings precarity takes over. The quiet gestures of unseen drawings that buzz in the head were let out for this project, manoeuvring anxieties to discoveries to speculations. This unorthodox actualizing reviewed predetermined propositions, escorted between foresight and hindsight that bounced in rhythm reviewing and reconsidering descriptions of thought. These embryonic and emergent fictions where possibilities unfold within their act, moving words and worlds around in alternative formats can became the ultimate speculative act. The fictions of drawing create an alterative access for thought: always ajar, always speculating. References Alaimo, S. and Hekman, S. (2008) Material Feminisms, Bloomington and Indianopolis: Indiana University. Badiou, A. (2006) Drawing, Lacanian Ink. Bonnefoy, Y. (1994) Overture: The Narrow Path Toward the Whole, (eds) Martine Reid Boundaries: Writing and Drawing, Yale French Studies. Cixous, H. (2005) Without End, No, State of Drawingness, No, Rather: The Executioner's Taking Off (trans, by .C. A. F. MacGillivray), in Stigmata: escaping texts; with a foreword by Jacques Derrida, London: Routledge. Davey, N. (2006) Art in theoria in L. Holdridge and K. Macleod (eds.), Thinking Through Art: reflections on art as research, Abingdon and New York: Routledge. De Certeau, M. (1998) Practices of Everyday Life, Berkeley and London: University of California Press. De Zegher, C. (2006) The Inside is the Outside: The Relational as the (Feminine) Space, in C. Armstrong and C. de Zegher, Women Artists at the Millennium, MIT Press. De Zegher, C. (2010) A Century under the Sign of the Line: Drawing and its Extension (1910-2010), in On Line: Drawing Through the Twentieth Century, Museum of Modern Art, New York. Merleau-Ponty. M. (1964), Signs, Northwestern University Press. Newman, A. & De Zegher, (2003) C. Conversation. In DE ZEGHER, C. ed. The Stage of Drawing: Gesture and Act, Selected from the Tate Collection. London. New York: Tate Publishing & The Drawing Center. 22 O’Donnell, L. (2016) Drawing Vignettes : ... perpetual becoming(s), PhD Thesis Loughborough: Loughborough University. Rabassa, J. (1993) Inventing A-M-E-R-I-C-A: Spanish Historiography and the Formation of Eurocentrism, Norman: University of Oklahoma Press. Reid Boundaries: Writing and Drawing, Yale French Studies. Ramirez, M. C. (1997), Re-Aligning Vision - Alternative currents in South American Drawing, The University of Texas at Austin. Sawdon, P. (2011), A Drawing Parlay, Soanyway. work_4oaus2gvfjejvcxy5fbs56sbt4 ---- Elvira Vilches. New World Gold: Cultural Anxiety and Monetary Disorder in Early Modern Spain. Elvira Vilches. New World Gold: Cultural Anxiety and Monetary Disorder in Early Modern Spain. New World Gold: Cultural Anxiety and Monetary Disorder in Early Modern Spain by Elvira Vilches Review by: J. H. Elliott The American Historical Review, Vol. 116, No. 4 (October 2011), p. 1200 Published by: The University of Chicago Press on behalf of the American Historical Association Stable URL: http://www.jstor.org/stable/10.1086/ahr.116.4.1200 . Accessed: 19/11/2011 17:11 Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at . http://www.jstor.org/page/info/about/policies/terms.jsp JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact support@jstor.org. The University of Chicago Press and American Historical Association are collaborating with JSTOR to digitize, preserve and extend access to The American Historical Review. http://www.jstor.org http://www.jstor.org/action/showPublisher?publisherCode=ucpress http://www.jstor.org/action/showPublisher?publisherCode=aha http://www.jstor.org/stable/10.1086/ahr.116.4.1200?origin=JSTOR-pdf http://www.jstor.org/page/info/about/policies/terms.jsp ELVIRA VILCHES. New World Gold: Cultural Anxiety and Monetary Disorder in Early Modern Spain. Chicago: Uni- versity of Chicago Press. 2010. Pp. xi, 361. $45.00. Elvira Vilches’s study of early modern Spanish eco- nomic theory and practice could hardly have been pub- lished at a more opportune moment. At a time when markets are in turmoil, and when the astronomical profits and bonuses enjoyed by bankers have aroused widespread suspicion, it is salutary to look back to a by no means incomparable situation in sixteenth and sev- enteenth-century Spain. This book explores with acu- men the responses of a society gripped by anxiety over the machinations of financiers. Vilches’s study is essentially of a society—primarily that of Castile—that was still imbued, like other Eu- ropean societies of the fifteenth and sixteenth centu- ries, with medieval ideals of a moral economy based on notions of a just price, but that found itself having to come to terms with the growing sophistication of bank- ing and the development of complex credit instruments like letters of exchange. The first trickle of American gold into Europe came with Christopher Columbus and was followed by a massive influx of both gold and silver that destabilized prices and helped provoke an inflation that contemporaries struggled to explain. Vilches be- gins by examining Columbus’s attitude toward gold and what she calls his “economy of the marvellous.” Then she goes on to explore “the new world of money” and the question of debt by means of a close reading of con- temporary texts, some of them the expressions of the neo-scholastic thought of the famous School of Sala- manca, and others by writers with practical experience of the money markets. Finally, moving into the seven- teenth century, she explores the links made both in imaginative literature and in the writings of the eco- nomic projectors, the so-called arbitristas, between Spanish decline and the gold and silver of the Indies. The story is by no means a new one. Spanish eco- nomic historians have done an enormous amount over the past few decades to illuminate not only the causes and consequences of the sixteenth-century price rise but also the workings of crown finance and the oper- ation of the fairs of exchange, like that of Medina del Campo. Many of the texts discussed by Vilches have been previously explored by Marjorie Grice-Hutchin- son (1952), but Vilches examines them in greater detail and goes beyond Grice-Hutchinson in discussing the work of writers with a close knowledge of contemporary business practice, notably Cristóbal de Villalón. The ar- bitristas, too, have received a great deal of attention in recent years, as has the equation made by contempo- raries between the influx of precious metals from Amer- ica and the decline of Spain. Vilches, however, retells the story well, and her book will be particularly welcomed by those readers who want a reliable and up-to-date account of early modern Spanish economic theory and practice but are unable to consult literature available in Spanish. It is perhaps un- fortunate that she places so much emphasis on gold at the expense of silver, not only in the title of her book but also in the body of the text. While it is true that gold remained the supreme metal and index of wealth, read- ers may not fully appreciate that from the middle years of the sixteenth century onward the influx of silver into Seville far outpaced that of gold, both in volume and in value. More unfortunate is the misdating of one of the authors she discusses. Francisco Martı́nez de la Mata wrote between 1650 and 1660 and does not belong to the group of early seventeenth-century writers among whom she places him. This is an ambitious book, in that it attempts to link a close reading of Spanish economic theory with the imaginative literature of the period. Vilches produces a picture of a society beleaguered by cultural and in- tellectual anxiety over what was happening to its tra- ditional values. Some readers may feel that the author tends, at times, to overinterpret her texts, and her book would have benefited from a deeper knowledge of both the general and the specific historical context of the works she discusses. Anxiety about credit and prices was not confined to sixteenth-century Spain, and the obsession with precious metals needs to be closely re- lated to problems of state expenditure as well as to the practices of money markets. Distinguished, however, by its impressive analytical grasp, this book provides valu- able insights into a world with disturbing parallels to our own. J. H. ELLIOTT Oriel College, University of Oxford DAVID GONZÁLEZ CRUZ. Propaganda e información en tiempos de guerra: España y América (1700–1714). (Sı́lex Universidad.) Madrid: Sı́lex. 2009. Pp. 304. $21.00. In this engaging book, David González Cruz brings to- gether two subfields seldom brought into conversation, at least in the historiography of early modern Spain. He seeks to merge perspectives and methods from military and cultural history in order to shed fresh light on the War of Spanish Succession. He focuses on the role of propaganda, though the book is at its most innovative in its discussion of techniques of misinformation, modes of censorship, and the painstaking construction of the public image of the two protagonists in the con- flict: Carlos of Austria and Philip V. The breadth and depth of González Cruz’s research is impressive. Be- sides consulting myriad collections in Spain, he has ob- tained valuable material from the archives of France, Argentina, Portugal, Mexico, Peru, and Bolivia. Such archival range proves indispensable to González Cruz’s story, for he seeks to portray the War of Spanish Suc- cession as a global conflict whose repercussions for the Spanish Atlantic monarchy were varied and multifari- ous. He largely succeeds in using the methods of cul- tural, social, and intellectual history to reconstruct a se- ries of episodes and practices neglected by traditional military historians. The book concerns propaganda only in the broadest, 1200 Reviews of Books AMERICAN HISTORICAL REVIEW OCTOBER 2011 work_4sl452zjhjfbnaranjisvfog3i ---- Microsoft Word - p399.docx International Journal of English Linguistics; Vol. 9, No. 4; 2019 ISSN 1923-869X E-ISSN 1923-8703 Published by Canadian Center of Science and Education 399 Reader-Response Theory and Dialogic Analysis of Gerald Vizenor’s The Heirs of Columbus Ghazala Rashid1 & Ali Ahmed Kharal1 1 Department of English, National University of Modern Languages, H-9 Islamabad, Pakistan Correspondence: Ghazala Rashid, Department of English, National University of Modern Languages, H-9 Islamabad, Pakistan. Tel: 92-320-858-0540. E-mail: ghazalarashidalam@gmail.com Received: June 17, 2019 Accepted: July 10, 2019 Online Published: July 23, 2019 doi:10.5539/ijel.v9n4p399 URL: https://doi.org/10.5539/ijel.v9n4p399 Abstract This article has employed the theory of Bakhtin’s (1895–1975) dialogism, and Wolfgang Iser’s (1926–2007) reader-response theory to examine the socio-political, and historical implications of Gerald Vizenor’s The Heirs of Columbus. The Heirs of Columbus (Heirs) was written to dismantle the historical oppression of Native Americans (NA) throughout the post Columbian era. Dialogism is an umbrella term that creates difference between historical and Native American discourse, providing new passages to comprehend the marginalized silenced other; in other words, it helps create a voice for the vanishing Indian. We have systematically identified the use of dialogic techniques like subversion, carnival, polyphony and heteroglossia in Heirs while, at the same time, analyzing his text through the framework of Iser’s reader-response theory. We have come to the conclusion that Iser’s theory is not enough to analyze Vizenor’s revolutionary text since Vizenor provokes his readers to draw their own conclusions rather than conforming to set of fixed ideals of author. Keywords: dialogism, hybridization, heteroglossia, reader’s response, discourse 1. Introduction Vizenor’s (1934–) Heirs is a subverted, mythical account of the discovery of America by Christopher Columbus that revolves around the themes of NA discrimination and oppression by the western world, re-connecting with tribal ethnic identity, and survivance (Vizenor & Vizenor, 1991). It presents the NA heirs i.e., Binn Columbus, Stone Columbus, Felipa, and Miigis flowers who are interested in recovering the human remains of Pocahontas, and their father Christopher Columbus. In his work, “The Dialogic Imagination: Four Essays”, Bakhtin (2010) emphasizes the importance of dialogue in language and text. According to him, we must open up to the possibility of dialogue, and alternative perspectives to break away from the tyranny of authoritative or monologic discourse. The purpose of a dialogic text is not only to create freedom of speech in the text, giving its readers a more realistic experience, it also provides and opens up the possibility of a better understanding of the text itself. It gives hope to the oppressed and misinterpreted voices that were otherwise, left unheard or overlooked in the realm of monologism (Baron, 2016). Therefore, the Native American (NA) literature is an ideal genre to be analyzed using the theoretical framework of dialogism and reader’s response theory since the writers of Native American literature are the proponents of the world of periphery, and also because these writers have to face issues like dual nationality, and are victims of stereotypical identity even though, they are an integral part of American historical landscape (Carmack, Gasco, & Gossen, 2016). Native Americans are the indigenous people who have a rich and vast historic connection with America; however, they have been subjected to centuries of displacement, relocation, and subjugation by the Eurocentric ‘White’ nation. The entire history of Native Americans is filled with power tussle with western invaders over the land. The strategic methods of oppression included forced conversions to Christianity, condemning tribal rituals, and the construction of reservations on the least desirable parts of land for natives (Mielke, 2018). Misinterpreting and molding the NA identity to benefit Western agenda is, however, the greatest mark of injustice done by western invaders. The work created by the Native American writers, in general, is symbolic of a hybridized ethnic identity, inculcated with primitive oral traditions that are still celebrated in the Native American world today (Barry, 2002). Gerald Vizenor is mixed blood, White Earth, Native American writer whose work strives to recreate and regenerate NA identity that can withstand and counterbalance the falsifications created by western dominated ijel.ccsenet.org International Journal of English Linguistics Vol. 9, No. 4; 2019 400 contemporary world. He has used subversion, heterogeneity and agnostic humor in his novels to describe the ethnic identity of the Native Americans. Therefore, these narratives provide us diverse, and vibrant accounts of NA culture while accomplishing the deconstruction of the Eurocentric literary canons (monologism). Speaking specifically about The Heirs of Columbus, Vizenor’s work has been identified in this study to possess dialogic aspects, to shatter the monologic frame of thought, and in the process, change the readers’ opinion by providing alternative perspectives to them. 1.1 Familiarizing with the Problem The novel under scrutiny, The Heirs of Columbus is a true representative of Gerald Vizenor’s work as a struggling Native American, and it also enlightens the readers about the subversive and carnivalesque nature of NA literature. Although Rebecca M. Lush (2012) has examined the role of sexuality and language games in Heirs, we have not found a single work that focuses on encompassing all the dialogic aspects present in Vizenor’s selected novel (a thorough Literature Review is presented in section 2). As discussed earlier, the true identity of Native Americans has been subjected to stereotypical representation by the Western literary society, and Vizenor’s work mainly aims to restore the NA identity to its original grandeur. We have linked the dialogic aspects in Vizenor’s work with the socio-political scenario of Native American history of subjugation which has not been done as yet. Vizenor has used ambivalence, carnival, polyphony, and heteroglossia in his text and left intentional gaps in the story to provoke his readers’ curiosity and set them free from the monologic literary catacombs embedded in their minds. Consequently, we have used Iser’s reader-response theory, to understand the link between Vizenor’s dialogic text, and its impact on readers; how far has he succeeded in shattering monologic frame of thought. We have picked a relatively old novel and analyzed it through a collaborative research approach that provides a fresh perspective on how dialogism has aided Vizenor in restoring NA identity to its former glory in literature. 1.2 Significance of the Problem This paper has highlighted dialogic aspects present in Vizenor’s Heirs, in light of NA socio-political, and cultural backdrop, employing reader-response theory. Dialogism is ubiquitous in approach and it is not just limited to literature; according to the theorist Bakhtin (2010), all language and thought processes are dialogic. Everything that is ever uttered or communicated in these languages by anyone, in reaction or in anticipation of things vice versa is interrelated and dynamic. These views are, as Bakhtin considers, persistently involved in the re-description and evolution of the literary world. Additionally, the process of redefinition or re-description of the world is very crucial to the Native American writers and novelists to restore their NA identity. The aim of Native American writers is not just to create a dialogic discourse, instead, they have to create a text that reinforces an identity that is vibrant, dynamic and can survive the harshness of the contemporary world. In Heirs, Vizenor (1991) has subverted the stereotypical, monologic accounts by using grotesque humor and imaginative metaphors while replacing the real entries from the journal, written and kept by Christopher Columbus, with the ambivalent, parodist encounters with natives. Thereby forcing the reader to examine and re-examine the text to grasp its true meaning and establish a dialogic perspective towards the history of America. 2. Literature Review Most of the research done on Heirs is based on postmodernist theory and trickster discourse. The work by Barry (2002) has analyzed the literary works of Gerald Vizenor from the postmodernist context. She has proposed that the symbolic representation of Bears in Chippewa traditions and religions holds key importance in Vizenor’s works. Similarly, Hockbruck (1992) has emphasized that Vizenor’s work tends to ‘breakaway’ from the established norms of language and literary works that were previously deemed characteristic to Native American narratives by critics. Russo (2017) contends that Vizenor has employed techniques code-switching technique and multi-voiced narrative to archive linguistic transmotion in The Heirs of Columbus. Therefore, none of the above-cited works have shed light on either dialogic content or the socio-political perspectives behind The Heirs of Columbus. We aim to enlighten the reader with the dialogic aspects of The Heirs of Columbus and also provide the socio-political background of Native American history that has driven Vizenor into writing the said narrative. The circle of Native American literature is ever expansive and requires constant pruning since it is still undergoing the developmental stages. Early attempts of writing by the Native American writers were mainly done to oppose or negate their established monologic ‘stagnant’ identity and explain the stance of Native Americans in the history of Eurocentric literature. Bleaser (1996) writes that the NA community has been deeply aggrieved by misinterpretation of their personality in literary works; their mischievous, humorous, and playful identity has been replaced with serious, authoritative, and hardcore traits. Therefore, stereotyping of Native ijel.ccsenet.org International Journal of English Linguistics Vol. 9, No. 4; 2019 401 identity has been strongly addressed by NA writers and often replaced with revolutionary ideals. Michael Fischer (1986) states, “Ethnicity is not something that is simply passed on from generation to generation, taught and learned; it is something dynamic, often unsuccessfully repressed or avoided”. Contemplating the dynamics of such an identity is, therefore, crucial to develop a proper understanding of the Native American perspective in literature. Native literature, as Fischer (1986) explains, can initiate for readers, “a dialectical or two-sided journey examining the realities of both sides of cultural differences so that they may mutually question each other, and thereby generate a realistic image of human possibilities and self-confidence for the explorer grounded in comparative understanding rather than ethnocentrism”. Gerald Vizenor is motivated to bring forth a body of text that is dependent on concepts like ethnicity, victimization, hybridization, social, and political persecution; he aims to bring forth a voice that can bridge the gap between the western world and the Native American indigenous world. Gerald Vizenor has also applied the postmodernist paradigms in his literary works; he differs from other writers of his era in his mediational approach towards NA oppression and his use of carnivalesque discourse to counter the grave realities of NA history. He deliberately creates a text that will be difficult to grasp by the reader in order to make them look for alternative approaches to understand the content and context behind it. The creation of a sovereign state in Heirs, one that celebrates tribal heritage and heals the wounded, abused children using genes of Christopher Columbus, at the end of the novel leaves the reader on a positive note. He sympathizes with Columbus in epilogue and believes that “Christopher Columbus, no doubt, would rather be remembered as an obscure healer in the humor of a novel and crossblood stories than a simulated quiver in national politics” (Vizenor, 1991). This paper aims are to identify the dialogic elements in Heirs, helpful in dealing with the issues related to hybridity and multiple ethnicities that have not been scrutinized by previous research to the best of our knowledge. 2.1 Theoretical Foundation The discerning factor about the NA literature is that it is deeply rooted with the issues concerning ethnic identity, nationalism; it also includes various literary theories like dialogism and reader-response theory of Wolfgang Iser. Therefore, the theoretical framework employed in this paper to critically analyze the selected novel involves a collaborative approach. By collaborative approach, we refer to combining the individual theories of Bakhtin’s dialogism and Iser’s reader-response criticism into a single theoretical framework for the investigation of selected work. Let us briefly elaborate on the collaborative approach before delving towards the dialogical aspects of the selected novel. 2.2 Why a Collaborative Approach? In our society we are often challenged with binaries; opposition coexists in specific forms; provoking questions like yes or no, right or wrong, men or women, up and down, good or evil, and civilization versus barbarianism. Due to these binaries, we are inclined towards only two-sided opinions however, Vizenor transgresses “… they don’t really absorb each other, do they? We hold them as opposites … force them to continue the dialectic” (Bleaser, 1996). Therefore, the problem lies with the dichotomous way of thinking that incites boundaries in the consciousness like good versus evil, black versus white, and right versus wrong etc., providing a Manichean ideology. However, the text provided by Gerald Vizenor is free from such constraints since such Manichean ideology only incites binary opposites in the society. According to him, a dialogic text has more potential to create multiple interpretations as he states that, “Any ‘living event’ must to a greater or lesser degree remain open”; this makes the text prone to generate multiple opinions and alternative perspectives, thereby making the text ambiguous, pre-suggestive, and open to limitless stylistic possibilities and engenders active participation on the part of the readers. These alternative perspectives provoke reader’s response which is purely based on his experiences, context and mental filter, restraining him from being conclusive about the interpretation of the text. Kimberly Bleaser writes about Vizenor’s intentional use of ambiguous and discursive language in his writing by quoting his words in one of his interviews: “literature ought to confront the comfortable values of authority. What other good is there for literature but to heal ourselves?” (Bleaser, 1996). According to her, at a certain juncture, Vizenor purposely writes in ambiguous style, creating confusion and indefiniteness in the minds of readers, forcing them to look for hidden meaning behind the text. Therefore, reading his novels is an interactive process that involves the readers in a literary process. The text created by Vizenor is labyrinthine, the subject matter, content, historic references and diction; everything is over complicated and deeply meaningful; the deconstruction of form and content is also part of his ambiguous text. Kimberley Bleaser states that his difficult style resists what he calls the “consumer mentality of the arts”, and he is perpetually trying to challenge the ijel.ccsenet.org International Journal of English Linguistics Vol. 9, No. 4; 2019 402 authority and the “terminal creeds” (a term coined by Vizenor to describe static ideologies of the society). He wants to question every comfortable niche of our consciousness to liberate ourselves from the stereotyping and to “push the consciousness” of the reader (Bleaser, 1996). Vizenor relies heavily on his active readers’ imagination to fill the gaps in his stories with their own perception of the truth and in doing so liberate themselves from monologic contingencies. Therefore, single theory is not sufficient to fully comprehend Vizenor’s work since it is multiple voiced discourse encompassing heterogeneity, polyphony, carnival, and heteroglossia. This is the reason that Bakhtin’s dialogism along with Wolfgang Iser’s reader-response theory has been employed to perform analysis of Vizenor’s selected work. 2.3 Bakhtin’s Interpretation of Dialogue Mikhail Bakhtin, having faced the oppressive rule of Stalin (1878–1953), gave birth to the concept of dialogism in the novel to celebrate freedom of thought by introducing dialogue in text. In Bakhtin’s dialogic novel, the readers “are to be led step by step from the popular view … to the truth which is merely and purely theoretical, guided by certain obtrusively enigmatic features in the presentation of the popular teaching—obscurity of the plan, contradictions, pseudonyms, inexact repetitions of earlier statements, strange expressions, etc.” (Strauss, 1941). Bakhtin used his analysis of Rabelais and Dostoevsky to contend that dialogue is inevitable in everyday life, generating ambivalence, contradictory perspectives, and inconsistent narratives and must form an integral part of the text, language, and thought. He shunned the monologic authority of the author in designing the fixed and unquestionable interpretation of the text and proposed the use of multiple-voiced discourse to provoke his readers’ interest and force them repeatedly read the text to reaffirm its implied meaning. Through the dialogic techniques of carnival, polyphony, and heteroglossia, he imagined his reader to transgress the monochromatic ideologies, liberating himself to form fresh, unique and imaginative alternative perspectives. Bakhtin’s dialogism has been accepted posthumously in NA literature since it aims to liberate its’ readers from the trite accounts of melodramatic history, and acts as a tool to invigorate their minds with multiple interpretations of verbal and non-verbal discourse. 2.4 Iser’s Interpretation of Implied Readers Wolfgang Iser’s stance on readers’ contribution in the literary process is attributed to his two major works i.e., The Implied Reader (1974), and The Act of Reading (1979). In these books, the text is interpreted as a collection of incomplete instructions that are completed by the reader, through his imagination and previous experiences. Iser’s reader employs the strategy of “wandering viewpoint” to process the text, familiarize with competing perspectives (not necessarily synchronous with his beliefs), and predict outcomes or fill in gaps, based on his enlightened apprehension, and past experiences. He constantly moves back and forth through the text, to confirm and reaffirm the contradicting ideas in the text and is open to revision in his initial opinions. Iser’s reader aims to achieve a holistic response from the text and is well aware of the limitations of his pre-mature beliefs that are harnessed before the reading process (Beach, 1993). Iser’s (1979) reader “combines all that he sees within his memory and establishes a pattern of consistency, the nature, and reliability of which will depend partly on the degree of attention he has paid during each phase of the journey. At no time, however, can he have a total view of that journey”. Steven Mailloux (2018) in his book Interpretive Conventions criticizes Iser’s reader by questioning the ultimate authority given to the author. Although Iser proclaims to give the reader primary importance in the reading process, he instructs the reader to choose from a predefined set of perspectives propagated by the author, ultimately favoring the author’s grand plan for the intended meaning of the text. Mailloux (2018) describes the gap-filling act of Iser’s reader as a predefined set of instructions, and professes that “… perspectives, blanks, and theme-and-horizon structure constitute the constraints that Iser’s account places on the reader’s interpretation of the whole text.” Similarly, Elizabeth Freund (2013) contends that Iser’s theory “presumes both an actively engaged reader employing cognitive strategies to create coherence, while, at the same time, the text’s schemata is also considered to be independent of the readers’ meaning-making”. It seems that Iser’s interpretation of the reader’s role is similar to the situation of students in academia who are instructed to bring out alternative interpretations of the text and then forced to adopt a particular perspective. Therefore, we can conclude that Iser’s reader isn’t as free to exercise his part as a reader and is dependent on the author’s projection of potential intended meanings, to arrive at a particular conclusion. Let us examine Vizenor’s work in this light and determine how far Iser’s implied reader succeeds in achieving closure from Vizenor’s Heirs. ijel.ccsenet.org International Journal of English Linguistics Vol. 9, No. 4; 2019 403 3. Methodology The above mentioned theoretical framework is employed by the authors in this paper to perform a compact analysis of Vizenor’s Heirs. Using the collaborative approach, by combining dialogism, and reader-response theory, our claim of dialogic as well as socio-political linkages in the selected work is further intensified and helps the reader in better deciphering the dialogical connotations buried in the text of the selected novel; these linkages also aid in understanding the stance of writer. We have incorporated adequate textual evidence in line of supporting the basic assumptions and make credible claims. Although incorporation of textual evidence is the tool used more often than not, we have also included citations of sources that concur with our claim in order to further validate our findings. 4. Analysis The Heirs was written in communion with the 500th anniversary of the first arrival of Columbus in America. The time of history mentioned in the novel creates a superior presence of White Nation (Eurocentric) in NA World which led to the inevitable loss of life, land, and NA identity. Vizenor has used language games and postmodernist discourse to create subversion of the stereotypes in the history of America. He rejects the idea of America being discovered, instead, he has weaved an imaginary account of Columbus being the descendant of the Native American origin, and the discovery of America is depicted merely as an act of coming back home of Christopher Columbus to his native homeland. Columbus is depicted as “an obscure cross blood who bore the tribal signature of survivance and ascended the culture of death in the Old World” (p. 3). He is mixed blood, as imagined by the writer, and a descendant of both Mayan (Indigenous origin) and Jewish origin. The roots of Columbus’ genealogy, therefore, go back to the lost tribes of Israel who traveled further than others towards Europe. 4.1 Polyphony and Its Intended Meaning By giving Columbus a tribal heritage, Vizenor has rendered European claim of discovery of America void, as he writes in the epilogue of the novel that it was never Columbus’ intention to settle on Native land and his decision was biased by the destruction of two out of three ships, under his command, at sea. The text is multiple voiced and dialogism is created by combining the historical facts recorded in the Eurocentric books with the NA oral traditions; multiple narrators take hold of the storytelling process and present their versions where each version is unique and never conforms to a single storyline. Dialogic narrative is created by discursive voices of Christopher Columbus and his heirs namely Binn Columbus (mother of Stone Columbus), Stone, Felipa (Stone’s partner) and Miigis flowers (Felipa and Stone’s daughter); the end of one narrative transcends the beginning of the second narrative giving rise to polyphony of voices. Stone Columbus’s narration of Christopher Columbus’ stories is often carried on by Christopher Columbus himself, as stories in the blood are common to all heirs of Mayan descent. In this bizarre New World, these descendants of Columbus are setting out to look for the remains of Columbus and Pocahontas; Felipa is a poacher, in addition to being a lawyer, who “repatriates tribal remains and sacred pouches from museums” (p. 8). Felipa and Stone’s character represents the notion of modern Native American as thriving and re-harmonizing individuals who can withstand the criticisms of the western dominated contemporary world; flexibility in their adherence to a particular school of thought, is the quality that Vizenor wants to endow upon his readers. He teaches his readers to adopt mediation as their ally in working through problems of their lives. Vizenor’s use of dialogism is the opposite of the established binary oppositions in the society and it is reflected in the novel when the concept of pure blood is deconstructed. Vizenor was strongly against the racial discrimination and he revisits this theme when Stone’s sovereign state is threatened by “tribal fascists who would abolish the heirs, their bingo, humor and certain words, such as crossblood, and the genes of survivance” (p. 131). Similarly, the western epistemology rejects the mixed-blood descent of mongrels since they prefer pure blood ties. But the mongrels are presented as the best race, in Hiers, that walks the face of this planet. Vizenor even went the extent to claim that “the best humans” are mongrels: Columbus, Jesus, Mayans, Jews, and Moors. He identifies with Bakhtin’s aversion to the hierarchical system of society and believes that through dialogic deconstruction of societal norms, one can achieve multiple perspectives and invoke freedom of expression to its’ fullest. 4.2 NA Oral Tradition, the Reader’s Response The ambiguity created by Vizenor provokes the reader to cultivate alternative perspectives and the intentional gaps left in the storyline are the source of imaginative response for the reader. The text itself invokes the reader’s mind to misinterpret the meaning intended behind it, all the while, creating confusion and chaos throughout the novel. In Heirs, Vizenor’s method of storytelling borders on incoherent narration; intentionally creating ijel.ccsenet.org International Journal of English Linguistics Vol. 9, No. 4; 2019 404 ambiguity with no hint of closure for the reader. Bleaser (1996) on the emersion of ideals from the work of Vizenor asserts in his book Gerald Vizenor: Writing in the Oral Tradition, that, “Vizenor’s immersion of events, ideas, and characters in a critical context (are) … Sometimes factual, sometimes fictional, sometimes both together, scenes and quotations fill Vizenor’s work as he juxtaposes the words or ideas of one writer or theorist against those of another, letting the context itself support, incriminate, or interrogate the ideas presented.” For example, Stone Columbus is never consistent about his historical account of C. Columbus and changes the details every time; when talking about his link with C. Columbus, he says “Samana … touched his soul and set the wounded adventurer free on October 28, 1492, at Bahia de Bariay” … “spell it out in your own words,” said Admiral White. “October 29, 1492, at Rio de la Luna.” “You changed the date.” “Columbus is ever on the move in our stories,” said Stone. So far, the Iser’s theory is coherent with the Vizenor’s expectation from his readers. The intentional gaps and theme-horizon structure has helped the researcher in comprehending the author’s as well as reader’s role in Heirs. In the first chapter, Vizenor channels his oral ancestral heritage and tells about Naanabozho as an earth diver trickster who has to climb a high mountain and use his own defecation to create a new world. From the dialogic perspective, this entire story of creation of the new world transgresses the story of creation of earth in Christianity, bridging the gaps in NA oral tribal stories and western epistemology. The satirical and a parodist twist are introduced into the novel to combine humor and pain altogether. The new world created by the trickster Naanabozho, mainly depicts Vizenor’s deep yearning for freedom of expression, void of racial, religious and cultural critique; this quest for freedom is transgressing the term ‘New World’, coined with the discovery of America as land of riches, hope and gold rush for the earlier settlers in America. This New World, established on the foundation of capitalism and racism is open to fresh beginnings and renowned as a land of opportunities. However, this entire concept is subverted by Vizenor in his novel when he mentions Naanabozho to create this world with piles of shit collected by him (p. 5). 4.3 Carnivalesque Discourse Vizenor uses humor to dismantle the established canons of the society. Bakhtin names this phenomenon as carnival and associates it with dialogism. Carnival is perceived as an ongoing social process that provokes laughter by subverting the establishment and traditional constructs of society. Vizenor is using this concept to amalgamate comic laughter emerging from joy and sorrow at the same time. For example, the character of Doric Mitchѐd is the physical personification of “tribal fascist” who “pretended to be tribal when his timeworn cross-blood heirs served his economic and political interests” (p. 47); His power tussle with Felipa over medicine pouches takes them to the court, however, fortunately Felipa in not indicted. Nevertheless, Doric succeeds in murdering Felipa to avenge his ego, reclaim his financial loss, and recover Christopher Columbus’ remains. Evidently, Vizenor combines the tragic with the comic in Heirs, therefore, the comic effect can never make us forget the underlying painful and violent history of colonization; the noxious gravity of Native American dialogue is never forgotten. Felipa is senselessly murdered while she is trying to restore ashes of Pocahontas. The cold corpse of Felipa was left unaccounted for by the Scotland Yard in the graveyard reminding us the brutal history of Native massacre of the past and “Binn held the moccasins to her ear and said that two men tied her down in a room, one man touched her breasts, the other man with the blood on his check watched and then he injected a poison into her thigh. Felipa dreamed that she was a mistle thrush in the tree over the church, she flew into a wicked storm and never returned …” (p. 175). Her killers are never convicted; in fact, Scotland Yard closes her case irresponsibly. The entire account is filled with the elements of subversion, humor and satire, often, overshadowing the melancholy and disheartening truths about NA oppression. After the establishment of sovereign state, the heirs use tribal stories, trickster humor and gene therapy to heal the “wounded and the lonesome”. “Panda and three robots were trained to heal with humor; their memories held the best trickster stories, and modern variations, that would liberate the mind and heal the bodies of children” (p. 158) who were subjected to abuse on the reservations. Therefore, the darkness of Native American history is clearly visible in the text of the novel and reminds the reader to re-think the stereotypical account of the events that have been presented by the Western World for centuries. Instead of highlighting NA oppression, the aim of Vizenor’s text is to bridge the gap between NA culture and western epistemology, is to create survivance literature; a literature that recreates and resists the historic facts to be the final truth and insists on NA ability to overcome the miseries of the past and move on, with hope on their side. Vizenor sympathizes with Columbus and contends that he was a survivalist who “escaped the culture of death and carried [his] tribal genes back to the New World” (p. 9). The interesting part of this narrative is that Columbus arrival at the Islands of America is the result of Columbus’ hearing stories carried “in the blood” that provoke him come back to reclaim his ancestry. “The Admiral of the Ocean Sea” has a clubbed penis and has ijel.ccsenet.org International Journal of English Linguistics Vol. 9, No. 4; 2019 405 suffered throughout his life, tormented by his deformity. Grotesque humor is, like Columbus’ genital dilemma, used to subdue the harshness of post-Columbian era and manifests the Vizenor’s ability to use humor in a unique and subverted manner. Ironically, Columbus meets tribal trickster Samana on the night of his arrival and is liberated by their sexual union thereby fathering the heirs. Examples of grotesque humor and sexuality are prevalent in the text as Columbus remembers his encounter with Samana, stating in a secret letter at sea, “his wild pleasures and liberation with a hand talker … she was the “first woman who moved me from the curse of my secret pain” (p. 31). 4.4 Heteroglossia Vizenor’s use of oral literature brings forth heteroglossia in his novel. Bakhtin defines heteroglossia as use of multiple speech genres, different signs and their hidden tensions governed by social, political and cultural backdrop at the time of creation of dialogue. For example, heteroglossia can represent different dialects as in Dickens works; use of oral literature as in Vizenor’s work. Now the “hidden tensions” part requires elaboration through an example. The conversation between Doric and Felipa while they argue over the rightful place of medicine pouches containing Columbus’ remains is marked with heteroglot text. “Stolen, is the right word,” whispered Felipa. “Discover is more accurate,” said Doric. “How much are your discoveries?” asked Felipa. (p. 50). Although argument is about medicine pouches but it points to the NA history and “discovery” of the New World in reality. Similarly, the word “stolen” in the argument, points to the western confiscation of native lands. Vizenor’s use of language games adds another dimension to the said heteroglot text and renders it more ambivalent, requiring its readers to revisit the history of America with suspicious attitude and question the documented facts rather than accepting them blindly. Here we see that Vizenor diverges from Iser’s viewpoint because he requires his readers to derive their own conclusions rather than relying on author’s intended interpretation of text. The narrative of this novel also sets out to criticize the history of colonization that included the wide spread massacre of the natives and that also involves centuries of relocation, persecution, subjugation and victimization of these people. The entire concept of discovering America, according to Vizenor, is demeaning and detrimental to the identity of the Native Americans. Vizenor believes that the word ‘Indian’ bears no identification, since it is nothing more than a mere misinterpretation created by the white people. Upon first contact the natives are not seen as the humans, instead their inability to understand the foreign language was associated with their poor intellect, Columbus was authorized by the king to take slaves therefore he saw potential for taking the natives as slaves; as mentioned in the novel he writes that, “They ought to make good and skilled servants, for they repeat very quickly whatever we say to them” (p. 4). These lines signify the stereotypical mentality of Columbus as the colonizer who construed a single-minded judgment about the livelihood and purpose of the natives. The above mentioned first entry of Columbus sealed the fate of the Native Americans who were seen nothing more than slaves. Kirkpatrick Sale believes that Columbus in the novel is not depicted as character, instead he is “an idea, manipulated by the author” (Sale, 1991). The second way to present Columbus is through the character of Stone Columbus who emulates Christopher Columbus. The mixed blood heirs are earth-divers: their objective is to submerge into the past and the present contemporary society, by jumping back and forth into the time so much so that they want to regenerate their origins and oppose colonization. Dialogically speaking, there is a constant overlapping of boundaries and time frames of the past and present are comingling to create ambiguity in the text. This ambiguity is provoking active response on behalf of its readers. According to Iser, by selection of single event for subversion in history, author opens up the numerous possibilities of conscientious awareness for reader, insinuating a perpetual dialogue, questioning the un-subverted facets of history. Iser differs from Vizenor’s point of view in that he relies on partial authority of author to achieve closure whereas Vizenor celebrates ambivalence and contends that closure is overrated in real life and the reader can change his perspective at any point in reading process. In Trickster of Liberty, Vizenor (2005) shares this point of view by saying that “… words are ambiguous.” “The word never has only one use,” he said at the seminar. “Every word always has a beyond, sustains several meanings. Behind what discourse says, there is what it means … and behind what it wants to say there is another meaning, and the process will never be exhausted.” 5. Discussion After performing the above mentioned analyses based on the hermeneutic theoretical framework, Vizenor’s The Heirs of Columbus has been identified to contain dialogic techniques of carnival, polyphony and heteroglossia. The oppression throughout history and its resulting anger seems to resonate in the hearts of Native Americans and even transcends the lapse of centuries, still igniting the hearts of younger generations. The stereotypical imagery of the Natives which had been honed in by the Western literature is unacceptable to the modern readers and writers. Vizenor’s use of dialogism has opened up the concept of alternative perspectives with regard to the ijel.ccsenet.org International Journal of English Linguistics Vol. 9, No. 4; 2019 406 true identity of Native Americans. Although Vizenor tries not to focus on the victimization of natives, he grieves the massacre of his native brothers by insinuating the death of one of the heirs i.e., Felipa Flowers. Nonetheless, the novel ends on an optimistic note of creation of a sovereign state by Stone Columbus which shelters the broken-hearted children and where tricksters heal their abused bodies and soul with their humor. The art of storytelling by tricksters is what saves the children and “Their best memories held the best trickster stories, and modern variations that would liberate the mind and heal the bodies of children” (p. 158). During our study we have identified that Iser’s reader-response is not enough to understand Vizenor’s text since he aims to transcend the realm of conventional norms of text and create ambivalent, subverted, multiple-voiced discourse that celebrates heteroglot thought processes and provokes contradiction and confusion, rather than proving closure. 6. Conclusion Text within The Heirs of Columbus is resonating with Vizenor’s use of dialogic techniques to bring forth alternative perspectives in the reader’s minds. Vizenor tries to discuss the ideals of native sovereignty by stating that the judge, at the hearing of Stone Columbus case in the novel, says that entire concept of tribal sovereignty “is imaginative … an idea that is more than metes and bounds in treaties” (p. 7). The idea of the novelist is to create a fresh perspective towards the Native American identity. He disregards viewing the Native Americans only as victims or savages. Ambivalence of responses is necessary to powerfully nurture the power of imagination. This novel perspective of carnival humor provides us with something new and it can also affect the native people to think differently about history and the horrible encounters between them and the colonizers. Vizenor, it seems, wants nothing more than to re-imagine alternative viewpoints, rejecting the imposition of stereotypes of society. This alternative and less intense way of thinking, in our view will, allow Native Americans to assimilate with the contemporary world and open up new pathways for their future while sustaining a healthy perspective towards past, present and future. We also contend that the basic techniques of dialogism in Heirs abide by Iser’s interpretation of reader’s response whereas heteroglossia demands its readers to take active part in interpreting the meaning of text rather than relying on author’s accepted set of responses. Conclusively our analysis reveals that there are clear differences in Iser’s implied reader and Vizenor’s active reader, the former is conformist while the latter is revolutionist in his approach. References Baron, R. (2016). Public folklore dialogism and critical heritage studies. International Journal of Heritage Studies, 22(8), 588–606. https://doi.org/10.1080/13527258.2016.1150320 Barry, N. B. (2002). Postmodern bears in the texts of Gerald Vizenor. 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American Indian Quarterly, 277–287. https://doi.org/10.2307/1185655 Vizenor, G., & Vizenor, G. R. (1991). The heirs of Columbus. Wesleyan University Press. Copyrights Copyright for this article is retained by the author, with first publication rights granted to the journal. This is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). work_4slasxjxwngzljbctg3npcchoa ---- ORIGINAL ARTICLES AAEM Ann Agric Environ Med 2000, 7, 119–123 Received: 8 November 2000 Accepted: 4 December 2000 PEPTIC ULCER AMONG POLISH RURAL POPULATION AND THE NICOTINIC INDEX Janusz Schabowski Clinic for Internal and Occupational Diseases, Institute of Agricultural Medicine, Lublin, Poland Schabowski J: Peptic ulcer among Polish rural population and the nicotinic index. Ann Agric Environ Med 2000, 7, 119–123. Abstract: The paper presents the results of observations concerning the effect of cigarette smoking on the prevalence of peptic ulcer among 6,512 rural inhabitants aged 20-64, selected by two-stage sampling. Of these, 2,506 (38.6%) were regular smokers. In order to determine precisely the negative effect of smoking on the human body the nicotinic index was used (N.I.), calculated by multiplying the number of cigarettes smoked daily by the period of smoking (years). The three-stage scale of the nicotinic index was applied: I° - N.I. < 100, II° - N.I. = 100-300, III° - N.I. > 300. The mean value of the nicotinic index calculated for the total number of smokers in the study was 290.3. A statistically significant higher N.I. was observed in patients with peptic ulcer - 432.5, compared to patients with other diseases - 337.2, and healthy individuals - 203.3. Among patients with peptic ulcer the highest percentage of people with N.I. > 300 was noted (59.0%), compared to patients with other diseases (42.9%) and those who were healthy (22.6%). The differences observed between patients with peptic ulcer and those of the remaining groups were highly statistically significant (p < 0.001). The percentage of people with the lowest value of the nicotinic index (N.I. < 100) in individual groups was: in patients with peptic ulcer - 13.5% (the lowest), among patients with other diseases - 25.0%, in the group of healthy individuals - 38.5% (the highest). An increase was noted in the incidence of peptic ulcer with the value of the nicotinic index. Peptic ulcer occurred in 3.8% of patients with N.I. < 100, in 6.4% of those with N.I. = 100- 300, and in 13.2% of patients with N.I. > 300. An increase in the percentage of patients with the nicotinic index was observed irrespective of the site of ulcer. It became most evident among patients who underwent surgical treatment due to peptic ulcer, where the highest value of the nicotinic index (N.I. > 300) was noted in 79.5%, in patients with gastric and duodenal ulcer - 66.7% and those with gastric ulcer - 59.6%. A positive correlation was observed between peptic ulcer incidence rates, complications of the disease and the value of the nicotinic index. The relationship between state of health and the value of the nicotinic index was confirmed. The results of the study showed that the nicotinic index was useful for determining the negative effect of cigarette smoking on the human body. Address for correspondence: Doc. dr hab. med. Janusz Schabowski, Clinic for Internal and Occupational Diseases, Institute of Agricultural Medicine, Jaczewskiego 2, P.O.Box 185, 20-950 Lublin, Poland. E-mail: schabow@galen.imw.lublin.pl Key words: Polish rural population, gastric ulcer, duodenal ulcer, peptic ulcer, surgical treatment, epidemiology, tobacco smoking, nicotinic index. INTRODUCTION Tobacco, a native plant of America, was brought to Europe at the time of Christopher Columbus’ expeditions. Initially, it was believed that this plant had therapeutic properties. Jean Nicot, a French ambassador to Portugal who contributed to the spread of tobacco cultivation, used tobacco leaves as a medical agent against migraine. The term nicotinism was derived from his surname and denotes the habit of tobacco smoking which in the second 120 Schabowski J half of the 20th century was considered as one of the greatest ‘killers’ of mankind. It has been discovered that tobacco smoking contributes to the occurrence of diseases of the respiratory and cardiovascular systems, alimentary tract, and also causes cancer. Based on the literature concerning etiopathogenesis of the peptic ulcer, tobacco smoking is one of the factors predisposing to this disease [5, 11, 14, 17, 18, 26]. Everyday medical practice provides substantial evidence confirming this hypothesis, e.g. longer healing time of ulcers among smokers, more frequent relapses of the disease and a greater number of complications. In addition, epidemiological observations suggest that there exists a relationship between cigarette smoking and the occurrence of peptic ulcer [1, 11, 13, 21, 22, 23, 27], although some reports also cast doubt on this theory [28]. It was observed that peptic ulcer patients who were smokers were twice as prone to relapses of the disease, and that sickness absenteeism was three times higher [5]. The results of treatment with the antagonists of H2 histamine receptor were similar to those obtained among non-smokers who were administered a placebo. A greater number of peptic ulcer complications was observed among smokers [4, 26]. In addition, higher mortality rates due to peptic ulcer were noted among smokers [4, 18]. The role of tobacco smoking in the pathogenesis of peptic ulcer has not been fully recognized. A considerable prevalence of this habit in Poland, as well as the lack of observations with the use of the nicotinic index, were the essential premises for conducting studies of this problem among rural population. MATERIALS AND METHODS The study was based on the results of the all-Polish comprehensive survey of the state of health of adult rural inhabitants conducted in 1990 by researchers from the Institute of Agricultural Medicine in Lublin, with the consideration of somatic, mental and social aspects of health [6, 25]. The analysis covered a representative group of rural population selected by the method of two-stage sampling. Records from all rural health centres in Poland (3,286), which are kept and annually updated by the Institute of Agricultural Medicine in Lublin, containing 34 parameters, were used for first-stage sampling. At the first stage of the study all health centres were divided into 150 groups according to their location, type of centre, distance to Health Unit (hospital), number of population in the region, percentage of farming population and deviation from the recommended model of employment. In each group two prevention-treatment regions were selected by means of stratified sampling and a sample of a required number of 300 first-stage units was obtained. The second- stage samples were selected based on communes where the selected health centres were located, and covered the population aged 18-64. According to the region and sampling probability the size of the sample ranged from 10 - 120 people from one health centre. A total number of 8,091 rural inhabitants were selected for the study, and 7,006 respondents, i.e. 86.6% were classified for the study (the remaining people did not report for examinations). The two youngest age groups (18-19) were considered as not sufficiently representative for further analysis. These deviations most probably resulted from the inadequacy of the 1988 electoral rolls (people who reached the age of 18 were not always enrolled on the lists). 6,846 people were classified for statistical calculations, including 6,512 rural inhabitants aged 20–64 with a correctly completed Medical Examinations Chart. The latter sample was analysed in the present paper. The study was conducted by trained rural health centre physicians and covered: a specially designed questionnaire, a detailed physical examination, and necessary laboratory tests. The results obtained were registered in a questionnaire, which also contained questions concerning detailed demographic and social data, hazardous agents present at the workplace, as well as data pertaining to housing conditions, mode of nutrition and habits. In order to determine the relationship between cigarette smoking and the occurrence of peptic ulcer the following parameters were analysed: prevalence of smoking, age at starting smoking, number of cigarettes smoked a day, and the period of smoking. Nicotinic index (N.I.) was analysed to determine the relationship between smoking and the occurrence of peptic ulcer. This index was calculated by multiplying the number of cigarettes smoked daily by the smoking period (years). The nicotinic index which covered two parameters - the number of cigarettes smoked a day and the period of smoking, should allow us to determine precisely the unfavourable effect of smoking on the human body. A three-degree scale of the nicotinic index was applied: I° - N.I. < 100, II° - N.I. from 100 to 300, III° - N.I. > 300. Chi2 test was used for analysis. Percentages were compared by means of a test of significance of differences between fractions. The level of p < 0.05 was adopted as significant. RESULTS At the time of study, the Polish rural population constituted 38.6% of the total number of Polish population, i.e. 14,623,000 people [21]. Among the total number of 6,512 rural inhabitants examined - 3,107 males and 3,405 females - 2,506 people (38.6%) were regular smokers, including 1,808 males (58.3%) and 690 females (20.6%); 678 (10.4%) - were ex-smokers, including 473 males (15.2%) and 205 females (6.0%); 3,314 (51.0%) were non-smokers, including 821 males (26.5%) and 2,493 females (73.4%). The mean value of the nicotinic index calculated for the total number of respondents was 290.3: for patients with peptic ulcer - 432.5, for patients with other diseases - Peptic ulcer among Polish rural population and the nicotinic index 121 337.2, and for healthy individuals - 203.3. The differences between the mean N.I. in patients with peptic ulcer and those with other diseases, as well as healthy individuals, were statistically significant (p < 0.001). The nicotinic index below 100 was noted among 29.6% of regular smokers in the study, N.I. = 100 to 300 - in 34%, and N.I. >300 - in 35.9%. Table 1 presents the compilation of patients with peptic ulcer, respondents with other diseases, and those who were healthy according to the nicotinic index. In individual groups, the percentage of people for whom the nicotinic index reached the highest value (N.I. > 300) was as follows: among patients with peptic ulcer - 59.0% (the highest); among patients with other diseases - 42.9%, whereas among healthy individuals - 22.6% (the lowest). The differences between patients with peptic ulcer and the remaining groups in the study were statistically significant (p < 0.001). The percentage of respondents for whom the value of the nicotinic index was the lowest (N.I. < 100) was as follows in individual groups: among patients with peptic ulcer - 13.5% (the lowest); among those with other diseases - 25.0%, and in healthy individuals - 38.5% (the highest). The differences observed between patients with peptic ulcer and the remaining groups were highly statistically significant (p < 0.001). It was observed that the percentage of patients with peptic ulcer considerably Table 1. Compilation of patients with peptic ulcer, those with other diseases, and healthy individuals according to the nicotinic index. Nicotinic index Patients with peptic ulcer (A) Patients with other diseases (B) Healthy individuals (C) Chi2 test value (DF = 1) n % n % n % A - B A - C < 100 33 13.5 387 25.0 475 38.5 15.4*** 56.3*** 100–300 67 27.5 497 32.1 480 38.9 2.1 11.9*** > 300 144 59.0 665 42.9 279 22.6 22.0*** 130.4*** Total 244 100 1,549 100 1,234 100 *** p < 0.001 Table 2. Prevalence of peptic ulcer among smokers according to the value of the nicotinic index. Groups in the study Nicotinic index < 100 100–300 > 300 n % n % n % Gastric ulcer 8 0.9 13 1.2 31 2.8 Duodenal ulcer 22 2.6 45 4.3 74 6.8 Gastric and duodenal ulcer 0 0 4 0.4 8 0,7 Patients who underwent surgical treatment due to peptic ulcer 3 0.3 5 0.5 31 2.8 Total 33 3.8 67 6.4 144 13.2 General number of respondents 895 100 1,044 100 1,088 100 Table 3. Site of ulcer among smokers by the value of the nicotinic index. Site of ulcer Nicotinic index Gastric ulcer (A) Duodenal ulcer (B) Gastric and duodenal ulcer (C) Patients who underwent surgical treatment due to peptic ulcer (D) Chi2 test value (DF =1) n % n % n % n % A - B A - C A - D < 100 8 15.4 22 15.6 0 0 3 7.7 0.02 - 0.52 100–300 13 25.0 45 31.9 4 33.3 5 12.8 0.09 0.05 2.08 > 300 31 59.6 74 52.5 8 66.7 31 79.5 0.78 0.02 4.05* Total 52 100 141 100 12 100 39 100 * p < 0.05 122 Schabowski J increased with the value of the nicotinic index. In this group, the percentage of patients with the highest value of the nicotinic index was significantly greater, compared to that noted for respondents with the lowest N.I. value. Table 2 presents the prevalence of peptic ulcer among smokers according to the value of the nicotinic index. It was noted that the incidence of peptic ulcer increased with the value of the nicotinic index. Peptic ulcer occurred in 3.8% of respondents with N.I. < 100; among 6.4% of those with N.I. = 100 to 300, and in 13.2% of people with N.I. > 300. Table 3 presents the compilation of sites of ulcer among smokers by the value of the nicotinic index. Considering each site of the ulcer, the percentage of patients increased with the nicotinic index. This was most clearly observed among patients who underwent surgical procedures due to peptic ulcer, where the highest value of the nicotinic index (N.I. > 300) was noted in 79.5% of respondents; while among patients with gastric and duodenal ulcer this percentage was 66.7%; and in those with gastric ulcer - 59.6%. The difference between patients who underwent surgical procedures due to peptic ulcer and those with gastric ulcer was statistically significant at p < 0.05. DISCUSSION Among the total number of 6,512 rural inhabitants in the study 38.6% were regular smokers (58.3% of males and 20.6% of females), 10.4% - were ex-smokers and 51.0% were non-smokers. Based on the results of the study conducted in 1987 it was estimated that 30.3% of rural inhabitants aged over 16 were regular smokers - 48.9% of males and 11.7% of females [19]. The greater percentage of smokers noted among the population under study may be due to both the age of respondents (over 20) and an increased prevalence of the smoking habit observed in Poland at that time. The application for the first time of the nicotinic index in order to evaluate the effect of smoking on the prevalence of peptic ulcer enabled us to prove statistically significant differences (p < 0.001) between the mean value of the nicotinic index among peptic ulcer patients (432.5), those who had other diseases (337.2) and healthy individuals (203.3). A significantly higher percentage of respondents with the highest values of the nicotinic index (p < 0.001) was noted among patients with peptic ulcer, compared with patients who had other diseases and healthy rural inhabitants; while the percentage of respondents with the lowest values of the nicotinic index was significantly lower (p < 0.001). Among people with the highest values of the nicotinic index (>300) the highest percentage of patients with peptic ulcer was observed (13.2%), while among people with the lowest N.I. values the number of peptic ulcer patients was 3.5 times lower. A considerably higher morbidity rates due to peptic ulcer were observed among smokers by Anda et al. >�@��- GU\FKRZVNL�et al. [11], Kato et al. [13], Sablich et al. >��@��6FKDERZVNL�DQG�6NU]\GáR- 5DGRPD�VND�>��@� Among patients who underwent surgical procedures due to peptic ulcer, the number of people with the highest nicotinic index was the greatest, compared to other sites of ulcer (p < 0.05). This confirmed the relationship between cigarette smoking and the occurrence of peptic ulcer complications which, in a large number of cases, lead to surgical treatment [4, 26]. Experimental studies, as well as the results of studies on humans, did not explicitly confirm the direct ulcer- inducing effect of nicotine. The widely - known effect of nicotine - a decrease in the production of bicarbonates by the pancreas - could be the only explanation for an increased probability of the occurrence of duodenal ulcer among smokers [14]. Reports concerning the unfavourable effect of smoking on gastric and pancreas secretion, as well as on the motor activity of the upper section of the alimentary tract, considerably expanded the knowledge of pathomechanisms associated with smoking [9, 14, 17, 26]. The last decade has brought to light many new data which confirm that smoking may possibly contribute to the pathogenesis of peptic ulcer. Ogle et al. [17] in their experiment conducted on rats observed an ulcer-inducing effect of nicotine. Cryer et al. [8] and Lindel et al. [16] showed a smaller level of prostaglandin in the mucous membrane of the stomach and duodenum in smokers, compared to non-smokers. Endoh and Leung [9] observed a decreased blood flow in the gastric mucosa due to nicotine. Jones et al. [12] indicated a decrease in the secretion of an epidermal growth factor (EGF) by the salivary glands in smokers with peptic ulcer, compared to non-smokers. The discovery of Helicobacter pylori (Hp) bacterium in the gastric mucosa essentially changed attitudes concerning the pathogenesis of peptic ulcer. It was found that this bacterium is an etiologic factor in about 90% of cases of duodenal ulcer and about 70% of cases of gastric ulcer. An effective eradication of Helicobacter pylori bacteria results in the complete recovery in the majority of peptic ulcer cases. It became evident that Hp infection is very prevalent - it concerns over 50% of the world population, males and females equally; peptic ulcer, however, is observed only in about 10–15% of the population infected, and is considerably more frequently among males [23, 24]. The studies showed that apart from an unfavourable effect on the defence mechanism of the gastric mucosa [8, 9, 14, 15, 16] cigarette smoking increases the risk of Helicobacter pylori infection and may contribute to the pathogenic effect of this bacterium. Bateson [2] observed that Helicobacter pylori infection concerns 49.6% of smokers and only 35.5% of non- smokers and ex-smokers. Bateson [2, 3] and Tursi et al. [29] noted that smoking decreases the immunologic resistance of the mucous membrane and increases Peptic ulcer among Polish rural population and the nicotinic index 123 Helicobacter pylori cytotoxic effect. Nicotinism is also associated with an increasing resistance to antibiotics [7] and poorer results of Hp eradication [10]. A more than three-fold increase in the incidence of peptic ulcer with the growing value of the nicotinic index, as well as a significantly higher percentage of people with high nicotinic index among peptic ulcer patients, compared to patients with other diseases and healthy individuals, confirm the role of smoking in the pathogenesis of peptic ulcer. The results of the study confirmed the usefulness of the nicotinic index for epidemiological assessment of the hazardous effect of cigarette smoking on the prevalence of peptic ulcer disease. CONCLUSIONS The studies conducted based on a representative group of 6,512 rural inhabitants aged 20-64 allowed us to draw the following conclusions: 1. A positive correlation was observed between peptic ulcer incidence rates and the value of the nicotinic index; among smokers with the highest index (>300) peptic ulcer was diagnosed in 13.2% of respondents, while in the group with the lowest N.I. value (<100) only in 3.8%. 2. Peptic ulcer complications leading to surgical procedure are associated with the growth in the nicotinic index. 3. Nicotinic index seems to be a good measure in the evaluation of the negative effect of cigarette smoking on the human body. REFERENCES 1. Anda RF, Williamson DF, Escobedo LG, Remington PL: Smoking and the risk of peptic ulcer disease among women in the United States. Arch Intern Med 1990, 150, 1437-1441. 2. Bateson MC: Cigarette smoking and Helicobacter pylori infection. Postgrad Med J 1993, 69, 41-44. 3. Bateson MC: Assessment of Helicobacter pylori infection. J R Soc Med 1994, 87, 125-126. 4. 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Watanabe Y, Kurata JH, Kawamoto K, Kawai K: Epidemiological study of peptic ulcer disease among Japanese and Koreans in Japan. J Clin Gastroenterol 1992, 15, 68-74. 28. :GRZLDN� /�� %URGDONR� %�� 5]HSHFND� %�� &KRU]\� QD� FKRURE � ZU]RGRZ�� L� LFK� ZLHG]D� QD� WHPDW� F]\QQLNyZ� ZSá\ZDM�F\FK� QD� MHM� powstanie i przebieg. (Patients with peptic ulcer and their knowledge concerning factors affecting its pathogenesis and course). Wiad Lek 1994, 47, 8-12 (in Polish). 29. Tursi A, Cammarota G, Papa A, Cianci R, Cuoco L, Fedeli G, Gasbarini G: Effect of adequate alcohol intake, with and without cigarette smoking, on the risk of Helicobacter pylori infection. Hepatogastroenterology 1998, 45, 1892-1895. work_4sydkzbb5vdtvave4pkubcbyxa ---- Various Types of Earth Buildings Procedia - Social and Behavioral Sciences 89 ( 2013 ) 226 – 230 1877-0428 © 2013 The Authors. Published by Elsevier Ltd. Selection and/or peer-review under responsibility of Prof. Dr. Huseyin Uzunboylu, Near East University, Faculty of Education, Cyprus doi: 10.1016/j.sbspro.2013.08.839 2nd Cyprus International Conference on Educational Research, (CY-ICER 2013) Various Types of Earth Buildings Hamed Niroumanda*, M.F.M Zainb, Maslina Jamilc a,b,cDepartment of architecture, Faculty of engineering and built environment, National University of Malaysia (UKM), Malaysia Abstract Earth architecture is a vernacular architecture. Earth architecture is included various types of buildings. This paper is described various types of earth buildings in the world. Rammed earth buildings, Cob, Adobe, Wattle and Daub, Poured earth are various types of earth buildings. The paper has shown the significant of earth buildings and earth architecture in vernacular architecture. Earth Architecture is a study devoted to the architectural uses of earth in shaping the environment of humankind, a subject closely related to human ecology. Earth Architecture includes contemporary as well as historical and vernacular examples drawn from many cultures and periods. Structural built of earth presently house an estimated 1.5 billion people about 30 percent of the world’s population (Keefe 2005). Archaeologists have found evidence of mud brick buildings constructed as early as ten thousand years ago in the Middle East and North Africa, where impressive buildings up to ten stories high have been recorded in an unbroken architectural tradition that continuous today. © 2013 Published by Elsevier Ltd. Selection and or peer-review under responsibility of Assoc. Prof. Dr. Zehra Özçınar, Ataturk Teacher Training Academy, North Cyprus Keywords: Adobe, Rammed earth, Wattle and Daub, Poured earth, Cob, Vernacular architecture; 1. Adobe Brick Building For wall construction, there has always been a comparison between adobe bricks and rammed earth. One of the major requirements for adobe bricks is climate. Some regular periods of dry weather is essential for the could to dry and the bricks to be structured firmly. This supports the common belief that adobe bricks are limited to arid lands only; however, this is not correct. Any area where climate supports a full week without rain is suitable. Adobe bricks (Figure 1) have also offered simple structural solutions for structures such as vaults, arches and domes, which are impossible to construct with rammed earth. A variety of soil can be used to manufacture adobe bricks. Based on the quality of bricks needed and the capital available for investment in the manufacturing tools, the manufacturing operation is established with different levels. Stabilizing agents such as bricks, mud and mortar are used for manufacturing adobe bricks. The factors on which the type of stabilizing agent is decided are cost and effectiveness. Other additives like asphalt emulsion, lime and Portland cement have also been used in mud bricks and walls. Vernacular builders in some cultures have also used many organic compounds that involve manure, straw, blood and plant juices. The number of advantages in using adobe brick walls is far more than the number of disadvantages associated with it. Some major advantages are low sound-transmission levels Available online at www.sciencedirect.com © 2013 The Authors. Published by Elsevier Ltd. Selection and/or peer-review under responsibility of Prof. Dr. Huseyin Uzunboylu, Near East University, Faculty of Education, Cyprus ScienceDirect Open access under CC BY-NC-ND license. Open access under CC BY-NC-ND license. http://creativecommons.org/licenses/by-nc-nd/3.0/ http://creativecommons.org/licenses/by-nc-nd/3.0/ 227 Hamed Niroumand et al. / Procedia - Social and Behavioral Sciences 89 ( 2013 ) 226 – 230 through walls, solidity and security. Such walls are also considered in selecting the heating, ventilating and cooling systems. Adobe bricks are found to be fireproof and the investment of energy in basic materials is also very low. The major disadvantage of using adobe bricks; however, is their extra wall thickness that considerably decreases the ratio between the total building space and the usable interior space. 2. Rammed Earth Building The man-made equivalent for sedimentary rocks is rammed earth. For more than many thousand years, builders are making use of simple tools to compact soil in order to produce rock-hard structures. This has created some very beautiful and well-known wonders in the construction industry. Examples of such great architectures include the Alhambra in Spain, the great Kasbahs of Morocco and the long stretches of the Great Wall of China. China has evidences of some of the most previous works built from rammed earth, where archaeologists discovered walls made of rammed earth back from the Longshan Culture of the Late Neolithic period (between 2600 and 1900 B.C.E), the period between the Stone Age and the Bronze Age, a period when many cities in China were established. This technology of building structures using rammed earth later spread throughout the Middle East. The Phoenician trading empire was the one that introduced the technology in Europe and helped in laying the foundations of the rammed earth city of Carthage. A famous Roman historian called Gaius Plinius Secundus stated that Carthaginians taught this technology to Romans, and Romans disseminated the technology throughout other territories. He also provided evidences of a fortification built out of rammed earth by Hannibal 250 years ago and also mentioned rammed earth walls in Spain in his studies. The Romans spread the technology to southern France through the Rhone River valley, where they built the capital city, Gaul, which is called Lyon today. In the city of Lyon, substantial evidences of agricultural buildings and houses made of rammed earth are still visible today. Native Americans were practicing the technology much before the arrival of Europeans in America. Another notable rammed earth structure that began construction in 100 C.E., in Teotihuacan, Mexico, is the famous Pyramid of the Sun. This structure was built using 2 million tons of rammed earth along with stone and rises to an impressive height of 207 feet. The first time rammed earth European traditions arrived in Americas was from Spain. The oldest remains of a European structure in America are a restructured earth house belonging to the first formal European settlement and the city of La Isabella in the Dominican Republic. Christopher Columbus founded this on his second voyage to America in the year 1493. The technology of rammed earth further spread into the southern United States and South America with the Spanish conquest. In the mid-19th century, Chinese immigrants that had arrived to participate in the gold rush in California brought this technology to the western coast of the United States. In Dutch flat in California, a small store that was constructed of rammed earth in the year 1877 by Chinese immigrants still remains. During the same time as the gold rush was raging in the West, French immigrants that arrived in the southern United States were constructing plantation houses, churches, slave quarters and schools out of rammed earth. Other notable examples of rammed earth construction are the historic campus of the Southwest School of Art and Craft in Sumter, South Carolina built in 1850. While rammed earth was building its emphasis in the United States, Australians, on the other hand, were beginning to establish towns by compacting the soil of the Central Australian desert. Many French-making countries renamed rammed earth walls “Pise”. Although when the rammed earth technology began is still not clear, researches conclude that it evolved from “puffed” mud wall construction. This is defined as a prehistoric mud type wall that was developed separately worldwide but is still currently used. Rammed earth walls that are placed with forms are similar to the construction using adobe bricks; however, the concept is totally different. 228 Hamed Niroumand et al. / Procedia - Social and Behavioral Sciences 89 ( 2013 ) 226 – 230 Rammed earth walls, in comparison to adobe bricks, are built in more damp, humid climates where building adobe bricks are practically impossible. In countries like North Africa and Australia, rammed earth has been considered a viable option although using adobe bricks in these arid-climate countries is not ruled out. Rammed earth is also widely used in France, Eastern Seaboard of the United States during the 19th Century, especially at the time of the unavailability of manufactured materials. E. Gilman wrote an early manual on constructing rammed earth walls in 1839; the manual was called “The Economical Euilder”. The manual mentioned the construction of rammed earth walls as highly sound and economical. The construction of rammed earth walls includes aggregate portions of silt, sand and clay and adding this mixture to the soil. This makes use of forms, usually of wood, that are placed and secured into damp earth. After drying for few days, the forms are removed and the wall structure is complete, except for curing. Once at this stage, the wall requires no further building except for furnishing it and performing some cosmetic treatments, etc. this is perhaps the most notable feature of rammed earth construction. Forms used can range from very simple small, wooden slip forms, secured with rope or wire, to patented manufactured forming systems used in concrete. The soil used is the same as that used in building adobe brick walls. The most suitable soil type; however, is the one that has small gravel aggregate, sand, silt and clay. Some qualities of the wall such as durability and waterproof qualities are based on the content of the clay in it, which is approximate 15-18%. For soils sued for rammed earth walls, higher clay content is preferred, while adobe bricks that are built using high clay content have a tendency to crack on drying. The moisture content in rammed earth initially is much lower and therefore, rammed earth walls are less subject to shrinkage on drying. A different form of rammed earth wall (Figure 2) construction that does not make use of forms is in Iran, called “chine” construction. This method makes use of damp mud and shapes it with hand. The wall comprises many successive layers, each 18-24 in. in thickness and 18-24 in. in height. The lower level has to dry completely before another layer can be placed on top of it. This technique is similar to the one used in “coil” pottery. However, this construction method is believed to not construct more strengthened wall structures like in case of adobe bricks and rammed earth using forms. In Iran, this type of wall is most often used for garden walls rather than structural building walls. Perhaps this indicates their lack of confidence in the structural qualities of this type of wall design. Other examples of such architecture can also be found in the Western Hemisphere at Casa Grande, Arizona and Casa Grandes, Chihuahua, Mexico, dating back almost a thousand years. 3. Cob The simplest of all earth-building technologies is called Cob. This technology makes use of very few tools and no formwork or internal structure and consists of piling and molding mud to create walls. The cob mix is similar to that of mud brick, however, it is stiffer and has higher straw content, which helps the mud hold its form as it is piled. Mud is shaped using trowel or hand and is placed directly in top of a structure at a height of approximately 18 inches around the perimeter of the building footprint. This is done by using a cob fork or a pitchfork - a traditional tool found in the United Kingdom – that are specifically designed for use in cob construction. Each layer in this construction is called a lift and must be dried completely for the next layer to be placed on top of it. Windows and doors are made as the wall grows and to increase the openings, wood or stone lintels are added after the wall is built completely. Because of the processes involved in building them, cob structures are highly sculptural. Openings in cob construction can be aligned using a pairing iron that helps in creating cleaner walls and edges. Because of its simple nature, cob construction has become very common in the whole world. Native Americans piled mud to create large multi-story dwellings. The ruins of Casa Grande, built using cob construction between 1200 and 1450 by the Hohokam culture near 229 Hamed Niroumand et al. / Procedia - Social and Behavioral Sciences 89 ( 2013 ) 226 – 230 Phoenix, Arizona, became the first prehistoric cultural site to be protected in the United States. The multi- story Taos Pueblo in New Mexico that was constructed using cob construction between 1000 and 1450 is the oldest continuously occupied dwelling in North America and still even today a thriving village. In northern Yemen, Zabur, as cob is called there, is a sophisticated tradition; multi-story dwelling and fortifications of piled mud flourished from the thirteenth to the nineteenth century. In Ireland, Scotland, Wales, Northern Ireland and England, many typologies from humble farmhouses to stately manors, as well as the birthplace of sixteenth century writer and explorer Sir Walter Raleigh were constructed of cob. With British colonization the use of cob spread to Australia, New Zealand, and North America. In New Zealand, English colonists constructed more than 8000 cob houses. 4. Wattle and Daub All this has made cob construction to be part of the present world in which we live. In the United Kingdom the long, curving cob wall in Associated Architects’ Cabtun House demonstrates how well suited this seismological design. In Heringer and Roswag’s design for a children’s school in Bangladesh, the sculptural potential of cob is explored in the caves carved out of the wall where students can study, play, or sleep. Wattle and daub is perhaps the oldest earth-building technologies in the world. Even before humankind had started to create societies based on farming, hunter-gatherer societies seemed shelter that could be made with ready materials that were available to a nomadic lifestyle. Tree branches were the most common construction material at that time to build the structural framework and mud plastered into the nest of interwoven branches to ensure protection from sun and other unfavorable weather conditions. In excavations of the oldest known settlements, such as Jericho and Catalhoyul, wattle and daub structures overpower the more permanent structures constructed using mud brick or rammed earth. The Wattle and daub technique consists of two parts. A wattle is a woven structure of small plant elements held together in a stiff frame. Common materials used to create wattle are reeds, bamboo, branches and twigs. Daub or mud adheres to the irregularities and overhangs of the organic matrix. This mud mixture is similar to the one used for mud brick but with smaller aggregate, and dung is often the organic binder. The daub in then smeared on to the wattle by hand until the entire surface is covered. When dry, either the finish surface can be a smooth final coat of daub, or it can be whitewashed with lime. Unlike other earth building systems, wattle and daub is very thin; however, it lacks the thermal mass properties rendered to the structure by rammed earth or adobe brick. However, the woven structure is highly earthquake resistant because it is extremely flexible. This is the reason why wattle and daub is used in seismic zones throughout the world such as South America and Indonesia. In addition to this, many Native American cultures of North America also employ wattle and daub as the primary construction method, and the United Kingdom is still home to a sophisticated array of examples of the technique. Indigenous and European Australian too used wattle and daub and it also flourishes throughout Europe and Asia. 5. Poured Earth Each of the four earth construction techniques mentioned here comprise pouring earth into frameworks and allowing it to dry. In case of wattle used for an exterior or an interior wall, the resulting gap is filled with mud. However, rammed earth construction requires laborious tamping where the resulting shape is achieved when the mud is completely dry. Based on the traditions prevalent in a region, the framework can serve as the primary structural support to the building. The Juana Briones Houses, built in 1845 near San Francisco, California, is a unique example of this construction type that is also called encajonado. This term is Spanish in origin that describes the process of stuffing mud into a framework of the lath. In the United Kingdom, many houses were built during the late eighteenth and early nineteenth centuries by using a mixture of chalk, straw and soil and pouring the mix into formwork. Once the material dried, the 230 Hamed Niroumand et al. / Procedia - Social and Behavioral Sciences 89 ( 2013 ) 226 – 230 formwork was removed to expose the brilliant white walls. This is similar to Marwan Al-Sayed’s use of gypsum in a poured earth wall in Phoenix, Arizona; the color renders the quality of lightness to the massive poured earth walls while reflecting the desert sun. Nader Khalili’s super adobe, in which flexible sacks of earth are stacked to create quick, low-cost disaster housing, is a radical take on poured earth traditions. 6. Conclusion The current paper is shown a review on various types of earth buildings. According to information, rammed earth houses are high performance buildings in earth buildings that they are developed in various countries. References Middleton, G. F. (1975). Build your own house of earth compendium Pty Ltd. Mentone, Victoria, Australia. Frank, R. Walker, Ed. (1954). The building estimator’s reference book, 12th ed., Frank R. Walker, Publisher Chicago. McHenry, P. G. (1984). Adobe and rammed earth buildings, John Wiley and Sons. Rael, R. (2009). Earth Architecture, Princeton Architectural Press, New York, USA. Morgan, W. N. (2008). Earth architecture from ancient to modern, University Press of Florida, USA. Niroumand, H., Zain, M.F.M., Jamil, M. (2011), Hill development by Earth architecture. 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C H E M I S T R Y Product Protection Chemical transformations often pose the dilemma that a desirable product may prove unstable under the reaction conditions. In certain cases, such intermediate products may be sufficiently volatile to be removed evaporatively from the reaction mixture as they are generated, but many compounds are not amenable to this mode of sep- aration. A particularly insidious challenge arises in the partial alkylation of amines. Adding an alkyl group renders an amine more nucleophilic than before, and so more likely to attract yet another alkyl group; therefore, simply mixing equivalent amounts of amines and alkyl electrophiles tends to afford a mixture of unreacted and polyalkylated products. Yebeutchou and Dalcanale skirt the 20 FEBRUARY 2009 VOL 323 SCIENCE www.sciencemag.org984 C R E D IT S ( T O P T O B O T T O M ): O L IV IE R W E IK E N /E P A /C O R B IS ; D ’A N G E L O E T A L ., C E L L 1 3 6 , 2 8 4 ( 2 0 0 9 ) EDITORS’CHOICE C E L L B I O L O G Y Aging Disgracefully As we age, all too many aspects of our physique deteriorate—not just at the macroscopic scale of our limbs and organs, but also at the single- cell level. Nuclear pores allow for the transport of proteins and nucleic acids across the nuclear envelope, both from the cytoplasm to the nucleus and in the reverse direction, and are essential in normal trafficking processes involved in gene expression, cellular homeostasis, and growth. Nuclear pores are complexes of many individual protein components, some of which are extraordi- narily long-lived. D’Angelo et al. have examined the characteris- tics of these complexes in aging postmitotic cells from Caenorhabditis elegans and from rodents, and find that as cells grow old, the lack of problem by adding molecular sequestering agents that selectively capture amines after their preliminary reaction step, thereby protecting them from further interaction with a methylating agent (iodomethane). The optimized protectors were tetra(arylphosphonate)-based cavitands that attracted monomethylated alkyl ammonium cations through ion-dipole forces, hydrogen bonding at the rim, and C-H–pi interactions deep in the cavity. In their presence, a range of alkyl and aryl primary amines could be selectively methylated in good yield. The authors verified preferential encapsulation of the secondary ammonium ions in solution using nuclear mag- netic resonance spectroscopy. — JSY J. Am. Chem. Soc. 131, 10.1021/ja809614y (2009). N E U R O S C I E N C E Opioids and Drink Substance abusers score higher on measures of cognitive and motor impulsivity. Cognitive impul- sivity refers to the inability to delay gratification, whereas motor impulsivity, or disinhibition, describes the inability to withhold a pre-potent response. Animal studies confirm that impulsivity EDITED BY GILBERT CHIN AND JAKE YESTON P S Y C H O L O G Y Cycling Between Worlds During the run-up to the first round of the 2007 presidential election in France, boundaries blurred as the usual mix of campaign rhetoric and dirty tricks spilled over into the virtual world of Second Life. Whether these skirmishes influenced the real-world electorate is unclear, and McCabe et al. have begun to investigate whether associa- tions learned within the confines of a computer- based contest might affect participants’ behavior in real-world situations. They conditioned partici- pants to chase or avoid cyclists who overtook them by linking one type of jersey logo to fruit juice and the other to salty tea, respectively. Several days later and in a different building, approximately two-thirds of the participants, while waiting for their turn in the brain scanner, elected to sit in a chair on which was draped a towel embroidered with the positively associated logo. Furthermore, neural activity of the insula region of the brain (a measure of motivational salience) reflected the previous conditioning of appetitive and aversive stimuli, hinting at a carryover from the virtual reality cycling competition. — GJC J. Neurosci. 29, 1046 (2009). Normally cyto- solic protein tubulin (green) inside an old nucleus. Published by AAAS o n A p ril 5 , 2 0 2 1 h ttp ://scie n ce .scie n ce m a g .o rg / D o w n lo a d e d fro m http://science.sciencemag.org/ www.sciencemag.org SCIENCE VOL 323 20 FEBRUARY 2009 C R E D IT : J U P IT E R I M A G E S correlates with drug intake, although nearly all of these studies have examined impulsivity in rela- tionship to psychostimulant drugs. Olmstead et al. have investigated whether deletion of the �- or �-opioid receptor genes alters motor impulsivity in mice. They tested the behavior of these mutant animals in an operant- based behavioral task that assesses the ability of mice to withhold a well-learned pre-potent response (a nose poke used to gain a sucrose reward); the reward can be obtained only when nose-poke responses are made during a brief light stimulus. Mice lacking �-opioid receptors exhib- ited decreased motor impulsivity, whereas those lacking �-opioid receptors showed increased motor impulsivity. Additionally, mice lacking �-opioid receptors were insensitive to the effects of alco- hol, which increases impulsivity and decreases conditioned responding in wild- type mice, and the behavior of mice lack- ing �-opioid receptors was completely disrupted by alcohol. Taken all together, these results indicate a link between opiate receptors in the brain, impulsive behavior, and behavior directed toward ingesting alcohol. — PRS PLoS ONE 4, e4410 (2009). M O L E C U L A R B I O L O G Y Finely Balanced Registers Many genes are interrupted by noncoding introns that must be precisely excised from the RNA molecules transcribed from the gene. In the first step of the splicing reaction, a large RNA- protein splicing machine recognizes the 5’ end of most introns via the complementarity of this region to one of the spliceosome components, the U1 RNA. Yet other 5’ splice sites show little complementarity to the canonical U1 sequence and are nonetheless efficiently and accurately spliced by the very same machine. In puzzling over this conundrum, Roca and Krainer noticed that a subset of these atypical 5’ splice sites did have a sequence that could form a base-paired region with the U1 sequence, but only if shifted one base downstream of the nor- mal 5’ splice site (the +1 register). Mutating one of these atypical 5’ splice sites to improve its complementarity to the U1 RNA in the canonical register resulted in aberrant, rather than improved, splicing. Furthermore, mutations in the +1, but not canonical, register of the U1 RNA that restored base pairing with the mutated atypical 5’ splice sites could rescue the splicing defects. Understanding that the U1 RNA can rec- ognize two subsets of 5’ splice sites in two regis- ters accounts for the splicing of atypical 5’ splice sites and also explains the deleterious effect of a mutation in the intron of the gene RARS2, which is associated with pontocerebellar hypoplasia. EDITORS’CHOICE 17050 Montebello Road Cupertino, California 95014 Email:AAASInfo@betchartexpeditions.com For a detailed brochure, please call (800) 252-4910 PERU June7-17,2009 Explore extraordinary cultural and archaeological wonders of Peru. Tour Lima and visit Huaca Pucclana archaeological site. See the heart of the Inca Empire at Cuzco and spec- tacular landscapes in the Andes. Visit Machu Picchu, Ollantaitambo, and Sacsayhuaman. $3,695 + air. Spitsbergen July14-26, 2009 Explore the Arctic and better understand global warming. Travel on board the M/V Antarctic Dream and see glaciers, wild- flowers, polar bears, walrus, Arctic fox, great whales, and much more! From $4,995 + air. Azores &Atlantic Crossing June 1-14, 2009 Cruise to the Azores on board the CleliaIIwith lectures at sea en route to Santa Maria where Christopher Columbus made landfall on his return from America. On the island of Sao Miguel, explore Ponta Delgada and breathtaking Sete Cidades, where two lakes fill a volcanic crater. Visit the islands of Terceira, Pico, and Faial. From $5,995 + air. China’s 2009 Eclipse July13-24, 2009 Visit three of China’s important cultural sites—Beijing, Xi’an, and Hangzhou—before seeing the Total Solar Eclipse, July 22, 2009 at the mouth of the Qiantang River near Hangzhou. $3,695 + air. Travel with AAAS Although the 5’ splice site mutation improves complementarity with the canonical U1 register, it weakens base pairing in the +1 register, and it is this imbalance that probably causes the exon skipping seen in the disease. — GR Nat. Struct. Molec. Biol. 16, 176 (2009). E N G I N E E R I N G Keeping Chips Cool The heat that is generated by silicon chips in the integrated circuits at the heart of modern elec- tronic devices must be efficiently removed, because the performance of field-effect transistors degrades at higher temperatures. One approach for providing active cooling next to a chip is to use thermo- electric materials, which effectively transport heat via current flow. Chowd- hury et al. fabricated a material with a high coeffi- cient of thermoelectric perform- ance and sandwiched it between the chip and a thermal sink layer. Specifically, the thermoelectric mate- rial comprised superlattices of p-type Bi 2 Te 3 /Sb 2 Te 3 and n-type Bi 2 Te 3 /Bi 2 Te 2.83 Se 0.17 grown on GaAs substrates by metal-organic chemical vapor depo- sition. The assembled devices could cool a targeted region on a silicon chip with a high heat flux (1300 W/cm2) by 15°C. — PDS Nat. Nanotechnol. 4, 10.1038/ NNANO.2008.417 (2009). A P P L I E D P H Y S I C S Sensing the Vibes Remotely Vibrations in machinery can lead to excessive wear, and, in the worst case, to catastrophic failure. Mon- itoring unwanted vibration is therefore an impor- tant safety issue. Probing the response of materials to vibrations at ultrasonic frequencies can provide a diagnostic test for defects and cracks in materials that may appear before the device breaks down. It is not always possible, or feasible, to use mechani- cally attached sensors, and so optical sensors may allow for nonintrusive monitoring. Bouncing laser light off a textured surface (such as a wall, a can, or paper) produces a speckle pattern. Bessette et al. introduce a photoconductive sensor that probes the movement of the speckle pattern as the sam- ple, in this case a metal surface cut from a can, is vibrated at high frequency. Using a simple silicon- based photoconductive element, which can be shrunk to micrometer size, they can look at the movement of a single speckle, thereby giving them the ability to monitor vibrations at ultrasonic fre- quencies remotely. — ISO Appl. Phys. Lett. 94, 41121 (2009). Published by AAAS o n A p ril 5 , 2 0 2 1 h ttp ://scie n ce .scie n ce m a g .o rg / D o w n lo a d e d fro m http://science.sciencemag.org/ Opioids and Drink Peter Stern DOI: 10.1126/science.323.5917.984d (5917), 984-985.323Science ARTICLE TOOLS http://science.sciencemag.org/content/323/5917/984.4 CONTENT RELATED file:/content/sci/323/5917/twil.full PERMISSIONS http://www.sciencemag.org/help/reprints-and-permissions Terms of ServiceUse of this article is subject to the is a registered trademark of AAAS.ScienceScience, 1200 New York Avenue NW, Washington, DC 20005. 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Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_4wkyvysyonhebi4vrn2zhz7xxq ---- Clinical Study Ingestion of Lycosome L-tug Formulation of Dark Chocolate Ameliorates Postprandial Hyperlipidemia and Hyperglycemia in Healthy Volunteers Ivan M. Petyaev ,1 Natalia E. Chalyk,2 Victor A. Klochkov,2 Dmitry V. Pristenskiy,1 Marina P. Chernyshova,1 and Nigel H. Kyle1 1Lycotec Ltd, Granta Park, Cambridge, CB21 6GP, UK 2Institute of Cardiology, 12 Chernyshevskogo Str, 410028 Saratov, Russia Correspondence should be addressed to Ivan M. Petyaev; ykb75035@aol.com Received 21 January 2019; Accepted 26 March 2019; Published 16 May 2019 Academic Editor: Gerardo E. Guillén Nieto Copyright © 2019 Ivan M. Petyaev et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Twenty-eight healthy middle-aged volunteers (40-60 years old) with equal gender representation were randomized into 3 study groups to investigate the changes in postprandial glucose and lipids after ingestion of different formulations of dark chocolate (DC). The volunteers from the first group were requested to ingest 100 g of regular DC whereas the individuals from the third group were given 100 g of highly bioavailable lycosome formulated L-tug formulation of DC containing 23.3 mg of lycopene. A second group received a 23.3 mg lycopene capsule, a tomato-derived antioxidant carotenoid as a matching control. Serum specimens were obtained following 30 minutes as well as 1, 2, and 3 hours after study products intake. Ingestion of L-tug DC was accompanied by the reduced postprandial hyperglycemia with maximum difference seen at3rd hour of the study and reduction of average AUCGluc values by 20% (P<0.05) as compared to regular DC. Moreover, ingestion of L-tug DC was accompanied by a statistically significantly reduced median concentrationfor postprandial triglycerides (to 390.7 mg∗hr/dL; 5/95%% CIs: 363.2/405.7 versus regular DC value of 439.5mg∗hr/dL and a lower range of confidence intervals - 5/95%CIs: 394.0/475.1). A similar tendency was observed in changes of total cholesterol concentration. Ingestion of L-tug DC completely abolished total cholesterol increase seen in volunteers at3rd hour of postprandial period following intake of the control DC. Ingestion of lycopene alone did not cause any changes in postprandial changes of glucose or serum lipids. The observed postprandial changes can be related to the 56.2 % increase in serum lycopene level which was observed after ingestion of L-tug DC only. Higher serum lycopene levels following the ingestion of L-tug DC resulted in a corresponding increase in serum antioxidant capacity and reduction of oxidized LDL as well as a decline in malonic dialdehyde concentration in the serum of volunteers. 1. Introduction The medicinal properties of dark chocolate (DC) and other foodstuffs derived from �eobroma cacao were first noted centuries ago dating back to the time of Christopher Colum- bus whose expeditions first brought cocoa to Europe and introduced DC into European culinary culture [1, 2]. Amelio- ration of fatigue, indigestion, and other gastrointestinal disor- ders were attributed to the potential medicinal benefits asso- ciated with regular consumption of DC [1]. Current nutri- tional science and numerous in vitro and in vivo studies sug- gest that DC intake may have a measurable effect on cardio- vascular health, the central nervous system, and intermediate metabolism [3]. DC contains nearly 300 identifiable chemical substances with conceivable biological activity. However, the medicinal effects of DC seem to be mediated largely by cocoa polyphenols, methylxanthines (caffeine, theobromine), and certain minerals: magnesium, zinc, and iron [1, 4]. The molecular interplay of these biologically active compounds and their individual role in the effects of DC are yet to be fully explored. However, it has been demonstrated that some of the physiological changes attributed to DC ingestion occur with the participation of a nitric oxide-mediated pathway, resulting in nitric oxide production via Ca2+-independent activation/phosphorylation of eNOS [3, 5]. Yet, there are legitimate concerns related to the consumption of DC by individuals with compromised health status. Currently, there Hindawi Advances in Preventive Medicine Volume 2019, Article ID 1659384, 8 pages https://doi.org/10.1155/2019/1659384 http://orcid.org/0000-0001-8201-6863 https://creativecommons.org/licenses/by/4.0/ https://doi.org/10.1155/2019/1659384 2 Advances in Preventive Medicine are no dietary guidelines and/or clear recommendations regarding daily intake of DC. Confectionery brands of DC contain more than 50g of fat, 20g of carbohydrates, half of which is sugar, with a total of 600 calories per 100 g [1]. Consequently, regular consumption of large amounts of DC may affect the outcomes of hyperlipidemia and type 2 diabetes mellitus. Therefore, there is a need to develop a new nutraceutical formulation of DC with limited impact on lipid and carbohydrate homeostasis. As we reported recently [6, 7], lycosome formulation of DC containing carotenoids embedded into DC matrix (L- tug DC) has a number of beneficial features including greater bioavailability of cocoa polyphenols and the ability to reduce the concentration of oxidized low density lipoproteins (ox- LDL) as well as other markers of biological oxidation and systemic blood pressure. In the present study we evaluate the effect of L-tug DC on postprandial lipids and glucose levels following acute ingestion as this had not been addressed previously. 2. Material and Methods 2.1. Study Objectives. The study was conducted by Lycotec Ltd (Cambridge, UK) and the Institute of Cardiology (Sara- tov State University, Russian Federation). The study was conducted as part of larger clinical trial under a protocol approved by the local Ethical Committee and registered (ACTRN12613000966796). The study was designed as a pilot, double-blind, interventional, randomized clinical study involving healthy middle-aged volunteers. The main objective of the study was to compare postpran- dial changes in serum lipids and glucose levels after single ingestion of 100 g of L-tug DC in comparison with the same amount of control DC over the first three-hour time window. The secondary objectives of the study included assessment of postprandial changes in markers of inflammatory and oxidative damage, which appear in the blood as a response to the transient challenge to the liver by postprandial lipids. In addition, total antioxidant capacity of the serum and serum lycopene levels were measured following ingestion of L-tug DC and DC. Since the former contained embedded lycopene, a separate group of volunteers was assigned to ingest the same dose of lycopene in capsule form without the intake of DC. All volunteers were aware of the purpose of the study and signed a written consent form regarding their partic- ipation. All volunteers underwent physical and laboratory examination and their medical history was evaluated during the enrolment period. 2.2. Subjects and Inclusion/Exclusion Criteria. Healthy Cau- casian male and female subjects 40–60 years old were enrolled in the study. Major inclusion criteria were assessed at the screening visit and were as follows: Caucasian individuals of both genders, aged 40-60 years, absence of any current disease, normal vital signs (blood pressure, body temper- ature, pulse, and respiration rate), and normal body mass index (BMI 18.5-24.9), as well as normal blood cell count and liver function parameters, no current intake of lipid- lowering, or any antidiabetic drugs. The exclusion criteria were inability to comply with the study protocol, concurrent medical conditions (hepatitis, pancreatitis, diabetes, cancer, recent cardiovascular events, tuberculosis, etc.), smoking (> 10 cigarettes per day), and intolerance to cocoa and tomato products. 2.3. Study Products 2.3.1. Dark Chocolate. Dark chocolate bars (100 g) with 85% cocoa from Green & Black's Organic (Uxbridge, UK) were used in the study. Nutritional characteristics per 100 g were as follows: calories - 630 kcal; protein – 9.2 g; fat – 53.5 g; and carbohydrates – 22.2 g, of which sugar was 13.8 g. The chocolate was melted, treated, and tempered in exactly the same way for all groups of the study regardless of the addition of lycopene. 2.3.2. L-tug� Formulation of Dark Chocolate. Modification of cocoa butter triglycerides by lycopene embedment into DC is accompanied by changes in the DC crystallization [6, 7]. This enhances bioavailability of cocoa flavanol compounds by protecting them from oxidative modification during the digestive process [6, 7]. The concentration of lycopene in the L-tug chocolate was 23.3 mg per 100 g bar. The lycopene used was in the form of tomato oleoresin from Lycored Inc. (New Jersey, NJ, USA) and contained 97% trans-isomers and 3% cis-isomers. 2.3.3. Lycopene. Lycopene control capsules containing 23.3 mg of lycopene were made from the same batch of tomato oleoresin that was used for the preparation of the L-tug DC. 2.4. Study Protocol. The volunteers were asked to refrain from consumption of cocoa- and tomato-based products for 10 days before beginning the study. The study participants were also asked to make no changes to their diet and lifestyle and to avoid vigorous physical activity and excessive alcohol consumption before the test procedure. The volunteers were asked to arrive at the study site fol- lowing overnight fasting (10-12 hours) and blood specimens were obtained within 30 minutes of arrival. The test products (100 g of DC with or without lycopene or 23.3 mg lycopene capsule) were given at the “0” time point of the study after obtaining fasting blood specimens. Volunteers were asked to consume the products within 5 minutes. From this time point a 3-hour observational period began. Volunteers were asked to remain in a sitting position and were allowed to consume 250 ml of regular drinking water with no food served before or after ingestion of the study products. Blood sampling was conducted at the “0” time point as well as after 30, 60, 120, and 180 minutes following consumption of study products. Neither the volunteers nor the study personnel was informed of the specification of the dark chocolate bars (presence or absence of lycopene in the DC matrix) during the interventional period or serum specimen processing/analysis. The lycopene alone ingestion group was unblinded for both the study personnel and the volunteers. An independent statistician and the principal investigator conducted the decoding of the results. All volunteers and https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=364779 Advances in Preventive Medicine 3 study personnel were informed of the study aims and objec- tives and had signed written consent for participation in the study. 2.5. Blood Sampling. Blood specimens were taken at the time points indicated above by qualified personnel. The specimens were allowed to clot at 37∘C for 30 minutes and were then centrifuged immediately in a refrigerated centrifuge (4∘C) at 3000 rpm for 10 minutes. The serum was separated and aliquots dispensed prior freezing at -80∘C. All quantification assays were performed at the same time in side-by-side assays with identical standards and reagents. 2.6. Biochemical Analysis. Total cholesterol (TC), triglyc- erides (TAG), HDL/LDL cholesterol, glucose, C-reactive protein (CRP), and alanine/aspartate aminotransferases (AST/ALT) were measured using a Biosystem A25 automated analyzer (Applied Biosystems, Grand Island, NY) using BioSys kits and calibrators. Total antioxidant capacity (TAC): frozen serum speci- mens were analyzed within 10 days of collection using Biorex reagents according to the manufacturer's instructions (Biorex Diagnostics, Antrim, UK). Results were expressed as mmol of Trolox equivalent (TE) per liter (mM TE/L). Oxidized LDL and malonic dialdehyde values were mea- sured in serum specimens as previously described in our work [5, 6]. Serum lycopene analysis was performed as recently described [8]. Briefly, 400 𝜇l of serum was mixed with 400 𝜇l of ethanol and was extracted twice with 2 ml hexane. The combined hexane layers were evaporated to dryness in a vacuum (Scan Speed 32 centrifuge) and the residue recon- stituted to a volume of 100 𝜇l in sample solution (absolute ethanol—methylene chloride, 5:1, v/v). The specimens were centrifuged again (15 min at 10,000 g) and clear supernatant was transferred to HPLC vials. Five microliters of the extract was injected into an Acquity HSS T3 75 x 2.1 mm 1.8𝜇m col- umn (Waters, MA, USA) preceded by an Acquity HSS T3 1.8 𝜇m VanGuard precolumn (Waters) and eluted isocratically at 45∘C with the mobile phase (acetonitrile—0.08% phosphoric acid solution—tert-butyl methyl ether, 70:5:25, v/v/v) at a flow rate of 0.5 ml/min. The lycopene peak was detected by a photodiode array detector (Waters) at 474 nm. The peak area was measured using Empower 3 software (Waters). The lycopene concentration in serum samples was calculated by reference to an analytical standard (lycopene from tomato, L9879; Sigma, USA). 2.7. Statistical Analysis. The results are shown as averages with standard deviation. For the assessment of normally distributed parameters, the Shapiro–Wilk method was used. Student's t-test was then applied for both paired and unpaired samples. Between-group differences at one time point were evaluated by the Wilcoxon–Mann–Whitney test (continu- ous variables) and Fisher's exact test (categorical variables). Serum levels of glucose and TAG were analyzed additionally using median values and 5% and 95% confidence intervals with box and whisker plot analysis. The 3-hour area under curve (AUC) was calculated using one-way ANOVA with further analysis using Tukey HSD test. Data analysis was performed using Stata SE (College Station, TX), version 12.1. All statistical tests were two-sided and statistical significance level alpha was set at 0.05 for the analysis. 3. Results 3.1. Baseline Parameters. Table 1 shows the variations of major baseline values in the volunteers enrolled in the study. As can be seen from Table 1, all participants enrolled in the study had normal BMI values and were normoglycemic and normolipidemic under conditions of overnight fast- ing. Moreover, normal serum AST and ALT levels suggest uncompromised liver function. No statistically significant variations were seen in gender representation and other baseline physiological values among the three groups of volunteers enrolled in the study. 3.2. Glucose Concentration. Figure 1 shows the dynamics of changes in serum glucose level after ingestion of control and L-tug dark chocolate. Both DC formulations gave a modest but statistically significant increase (p<0.05) in serum glucose values over the postabsorption period with a maximum peak registered 30 minutes after DC intake. However, the serum glucose levels were noticeably higher following ingestion of the regular formulation of dark chocolate at all-time points studied (Figure 1(a)) which was reflected by a higher mean AUC value as compared to L-tug DC (Figure 1(b)). In particular, ingestion of regular DC gave an increase in average serum glucose concentration by 52.2, 34.0, 23.8, and 17.0 % after 30 minutes or 1, 2, and 3 hours, respectively, of the postingestion period, whereas the corresponding increases in serum glucose after L-tug DC ingestion were distinctly less significant (40.2; 9.1; 2.09; and -3.6% accordingly). This muted glycemic response resulted in lower AUC values (Figure 1(b)) in the L-tug DC group (reduction of average AUC values by 20.0%). Ingestion of lycopene alone in capsule form did not give any measurable changes in serum glucose levels (results not plotted). 3.3. Triglyceride Levels. Regardless of the study group, an increase in average TAG values in serum took place over the course of 1 hour following DC ingestion with no statistically significant differences at the 30-minute time point or at the first hour following ingestion of DC for either group. However, after the second hour and especially after the third hour of the observational period the serum triglyceride level was higher in volunteers ingesting regular DC (p<0.05). This resulted in reduction of TAGAUC shown in Figure 2. The ingestion of L-tug DC was accompanied by a lower median for AUCTAG (390.7 mg∗hr/dl) and a lower range of confidence intervals (5/95%CIs: 394.0/475.1)) as compared to regular formulation of DC (median - 439.5mg∗hr/dl; 5/95% CIs: 363.2/405.7). This difference was statistically significant with a p value of 0.034. The analysis of statistical differences in paired variables (“0” time point versus third hour of the postprandial period) revealed that ingestion of L-tug DC leads to a statistically 4 Advances in Preventive Medicine Table 1: Baseline values of fasting study participants (averages±SD). Parameter Study Groups Regular DC Lycopene L-tug DC Age 49.3±4.1 54.3±3.7 51.6±5.3 Men/Women 4/5 4/4 5/5 BMI 22.3±1.1 21.5±1.4 23.0±1.2 Serum Glucose mg/dl 85.3±5.6 81.3±6.3 79.4±4.9 Serum Triglycerides mg/dl 130.6±7.3 121.4±4.2 129.9±5.3 Total Cholesterol mg/dl 167.5±8.3 174.6±14.5 181.5±12.3 LDL Cholesterol mg/dl 112.8±8.3 127.5±12.5 105.6±10.3 HDL Cholesterol mg/dl 37.2±3.1 41.4±2.9 39.4±3.3 AST IU/ml 34.3±6.3 27.2±7.4 35.9±4.2 ALT IU/ml 44.6±3.5 37.8±6.9 45.6±5.5 CRP mg/l 2.1±0.6 1.7±0.8 2.3±0.4 TAC 1.76±0.09 1.79±0.09 1.74±0.10 Pulse Rate beats/min 74.3±4.22 71.8±3.99 76.5±4.76 Blood Pressure mm Hg Systolic: 108.3±6.2 110.1±4.1 111.7±4.5 Diastolic: 78.3±5.3 75.3±5.8 74.6±4.1 0 h 0.5 h 1 h 2 h 3 h DC L-tug DC 0 20 40 60 80 100 120 140 160 G lu co se (m g/ dl ) (a) Reguar DC L-tug DC p<0.05 0 50 100 150 200 250 300 350 400 G lu co se A U C (m g∗ hr /d l) (b) Figure 1: Changes in serum glucose (a) and area under the curve (AUC, (b)) for serum glucose concentration after ingestion of regular and L-tug dark chocolate (DC). Regular DC L-tug DC p=0.034 300 320 340 360 380 400 420 440 460 480 500 Tr ig ly ce ri de A U C (m g∗ h/ dl ) Figure 2: Changes in area under the curve (AUC) values for serum triglyceride concentration after ingestion of regular and L-tug DC. Advances in Preventive Medicine 5 "0" hour 3rd hour "0" hour 3rd hour p<0.05 p>0.05 Regular DC L-tug DC 150 160 170 180 190 200 210 220 To ta l C ho le st er ol (m g/ dl ) Figure 3: Changes in serum total cholesterol concentration after ingestion of regular and L-tug DC. (“p” reflects the statistical difference between initial and final values). significant reduction in medians reflecting serum TAG con- centration as compared to regular DC. The net increase in the postprandial serum TAG content after ingestion of regular DC was +18.0 mg/dl (5/95% CIs:4.8/31.2) whereas the value for L-tug DC was +5.0 mg/dl (5/95% CIs: 1.4/8.6, p<0.05) suggesting altogether a 2.6-fold difference between the groups. Once again, ingestion of lycopene alone did not result in any significant changes to triglyceride concentration at any of the time points studied (results not plotted). 3.4. Total Cholesterol (TC). Changes in TC concentration developed in a manner similar to the triglyceride dynamics described above. The variations in TC content were statisti- cally insignificant at early time points of the observational period. However, at the third hour of the postprandial period there was a noticeable difference between the groups (Figure 3). There was an increase in TC concentration for the regular DC group in both medians (from 173.5 mg/dl to 193.5 mg/dl) as well as confidence intervals (from 5/95% CIs: 163.1/183.5 to 186.2/206.4, p<0.05). On the other hand, there were no changes in serum TC content for the L-tug DC group at the third hour of the postprandial period (p>0.05). Ingestion of lycopene alone did not result in changes to TC concentrations (results not plotted). 3.5. Serum Lycopene Values. As can be seen from Table 2, ingestion of regular DC did not affect postprandial value of serum lycopene concentration at the end point of the observational period. No immediate effect of ingestion of lycopene alone was seen on serum lycopene level in the 3-hour time window following ingestion either. However, there was a statistically significant increase in serum lycopene concentration (Table 2) in volunteers ingesting L-tug DC at the end of the third hour following intake. Figure 4 provides a better insight into variations of lycopene concentration at the end point of the observational period in the study groups. Serum levels of lycopene were almost equal in the volunteers ingesting either regular DC or lycopene alone (median values of 0.156 and 0.147 𝜇g/ml, respectively). However, ingestion of L-tug DC resulted in much higher values for lycopene concentration at the end of the observational period (median - 0.244𝜇g/ml, 5/95% CIs: 0.164/0.406). 3.6. Serum Total Antioxidant Capacity (TAC). There was a different pattern of changes for TAC parameters at the end point of the observational period. As can be seen from Figure 5, ingestion of regular DC was accompanied by a small postprandial increase in TAC medians-up to 1.96 mM TE/L (5/95% Cis: 1.86/2.02) as compared to time “0” (1.75 mM TE/L, 5/95% Cis:1.66/0.40). Ingestion of lycopene alone did not give any changes in TAC (p>0.05), which is consistent with the unchanged serum lycopene level for this group shown in Table 2. However, the most significant increase in TAC values took place in the serum of volunteers who ingested L-tug DC (2.05 mM TE/L; 5/95% Cis: 1.94/2.14) versus time “0” – median 1.74 mM TE/L (5/95%Cis:1.61/1.86). 3.7. Oxidized LDL (ox-LDL) and Malonic Dialdehyde (MDA). Table 3 shows between group differences in ox-LDL and malonic dialdehyde concentrations at the end of the obser- vational period. As can be seen, volunteers ingesting regular DC or lycopene alone showed no statistically significant difference in ox-LDL or MDA concentration. However, there was a postprandial reduction in average ox-LDL and MDA levels following the ingestion of L-tug DC (by 22.7% and 36.8 %, respectively). 4. Discussion Postprandial increases in serum triglyceride, cholesterol, and glucose levels are a normal physiological response to fat and carbohydrate containing meals which depend on health status, age, composition of meals, and time following intake. Recently these increases have gained particular attention as new discoveries reveal their key significance for human health. Repeated episodes of postprandial hyperglycemia (>140 mg/dl) are associated with a two-fold increase in risk of death from cardiovascular disease in healthy normoglycemic individuals with HB1c<6.1 [9, 10]. Similarly, increased post- prandial TAG responses are now considered as an indepen- dent risk factor for atherosclerosis. An increase of 1 mmol/l in fasting TAG level increases risk of the cardiovascular disease by 14% [11]. As shown, ingestion of L-tug formulation of DC blunts postprandial increases in triglycerides, cholesterol, and serum glucose as compared to control DC without lycopene. The decline in postprandial lipids observed in volunteers ingesting L-tug DC is consistent with our previously reported observation that ingestion of L-tug DC resulted in reduction of the fasting level of these lipids [6]. Incorporation of lycopene, a highly lipophilic compound, into cocoa butter triglycerides enlarges the size of their globular / crystal structures in the chocolate matrix which results in reduction of their digestibility. In addition, lycosome particles are relatively stable in the gastrointestinal environment and are known to penetrate the intestinal epithelium at least partially in native form [12]. Presence of lycopene, a powerful ligand for hepatic carotenoid receptors, in the outer layer of lyco- some particles may promote faster and more efficient clear- ance from the bloodstream via hepatic scavenger receptors and ameliorate thereby postprandial hypertriglyceridemia and hypercholesterolemia. 6 Advances in Preventive Medicine Table 2: Serum lycopene concentration (𝜇g/ml) in volunteers at3rd hour after ingestion L-tug DC (averages±SD). Time Point Study Groups Regular DC Lycopene L-tug DC “0” hour 0.14±0.04 0.13±0.04 0.15±0.03 “3”hour 0.16±0.03 0.15±0.03 0.25±0.07∗ (∗) – p<0.05 Table 3: Serum oxidized LDL (ox-LDL) and malonic dialdehyde (MDA) levels in volunteers 3 hours after ingestion of dc formulations (averages±SD). Study Groups “0” Hour “3rd” hour Ox-LDL (ELISA UNITS x 10−3) Regular DC 631.58±16.21 611.56±14.11 Lycopene 644.65±12.95 669.43±15.33 L-tug DC 674.78±12.32 521.23±18.21∗ MDA (𝜇M) Regular DC 123.67±8.31 141.21±11.21 Lycopene 131.25±9.94 118.25±10.41 L-tug DC 119.25±8.66 75.34±12.33∗ (∗) – p<0.05 Regular DC Lycopene Lycosome DC Study Groups p<0.05 p>0.05 0 0.05 0.1 0.15 0.2 0.25 0.3 0.35 0.4 0.45 0.5 Ly co pe ne ( g/ m l) Figure 4: Box-and-whisker analysis. Serum lycopene level after 3 hours following ingestion of L-tug DC (“p” value reflects statistical difference in lycopene concentration among study groups as compared to regular DC group). 3 h0 h3 h0 h3 h0 h Regular DC L-tug DCLycopene Study Groups p<0.05 p>0.05 p<0.05 1.5 1.6 1.7 1.8 1.9 2 2.1 2.2 TA C m M T E/ L Figure 5: Box-and-whisker analysis. Postprandial changes in total antioxidant capacity of serum in volunteers following ingestion of L-tug DC. “p” values reflect intragroup differences between initial and final values. Advances in Preventive Medicine 7 Serum lycopene changes observed in our study and possible relation to postprandial responses require careful consideration. Lycopene is highly hydrophobic and poorly absorbed from the gastrointestinal lumen [13, 14]. Even long- term consumption of lycopene-containing foodstuffs and / or lycopene supplements may not lead to significant increase in serum concentration, especially in elderly individuals [14]. Thus, the unchanged lycopene levels seen in volunteers ingesting lycopene alone correlate well with reports reveal- ing low bioavailability of lycopene [13–15]. Coingestion of lycopene with fat-containing products promotes its intestinal absorption [16], explaining the increase in lycopene level with L-tug DC. A combination of two possible mechanisms, reduction in digestibility of cocoa butter, and formation of lycosome structures, which provide increased bioavailability for both lycopene and cocoa bioactives [17], seems the most likely explanation for the beneficial effects of L-tug DC. It was surprising and encouraging to observe a reduction in postprandial hyperglycemia following ingestion of L-tug DC. There is no well-documented link between dietary lycopene and frequency of type 2 diabetes mellitus [18]. How- ever, recent results show that lycopene may increase insulin sensitivity and prevent hyperglycemia through inhibition of the STAT-3/SREBP-1c pathway [19]. Moreover, cocoa fla- vanols seem to affect glucose turnover, reportedly enhancing insulin secretion and sensitivity reducing thereby glucose lev- els [20]. Therefore, potentiated effect of lycopene and cocoa polyphenols on glucose hemostasis may reduce postprandial hyperglycemia as observed with L-tug DC. This is in good agreement with changes in total antioxidant capacity (TAC), which mirrored increase in serum lycopene concentration. As shown above, ingestion of regular DC and especially L- tug DC gives statistically significant postprandial increases in TAC values accompanied in the last group of the study by reduction in postprandial concentration of ox-LDL and malonic dialdehyde. This reveals that postprandial increase in serum lycopene content following the ingestion of L-tug DC is essential for amelioration of oxidative stress markers even in healthy individuals. Elucidation of a potential link between serum antioxidant levels, postprandial hyperglycemia, and markers of oxidative stress requires further thorough inves- tigation. Our study has some limitations: ingestion of 100g of DC is not a recommendable dietary option and was only used for testing purposes. Future studies should verify if smaller amounts of DC with higher amounts of lycopene would help maintain glucose and TAG levels, especially in subjects with metabolic syndrome and type 2 diabetes patients. A higher number of volunteers would obviously be required for further evaluation. Data Availability The supporting results will be displayed on the publicly avail- able website Lycotec.com. Moreover, the data that support the findings of this study are available from the corresponding author, Dr. Ivan M Petyaev, upon reasonable request. Conflicts of Interest The authors declare no conflicts of interest involved. Acknowledgments The study was funded by equal contributions of Lycotec Ltd. (Cambridge, United Kingdom) and Institute of Cardiology (Saratov State Medical University, Saratov, Russia). References [1] I. M. Petyaev and Y. K. Bashmakov, “Dark chocolate: oppor- tunity for an alliance between medical science and the food industry?” Frontiers in Nutrition, vol. 4, no. 43, 2017. 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Petyaev, “Lycopene deficiency in ageing and cardiovas- cular disease,” Oxidative Medicine and Cellular Longevity, vol. 2016, Article ID 3218605, 6 pages, 2016. [15] R. K. Saini, S. H. Nile, and S. W. Park, “Carotenoids from fruits and vegetables: Chemistry, analysis occurrence, bioavailability and biological activities,” Food Research International, vol. 76 (Pt 3), pp. 735–750, 2015. [16] L. Mutsokoti, A. Panozzo, A. Pallares Pallares et al., “Carotenoid bioaccessibility and the relation to lipid digestion: a kinetic study,” Food Chemistry, vol. 232, pp. 124–134, 2017. [17] I. M. Petyaev, D. Pristenskiy, T. Bandaletova et al., “Lycosome formulation of dark chocolate increases absorption cocoa cat- echins and augments their anti-inflammatory and antioxidant properties,” American Journal of Food Science and Nutrition, vol. 3, no. 3, pp. 37–44, 2016. [18] M. A. Valero, A. Vidal, R. Burgos et al., “Meta-analysis on the role of lycopene in type 2 diabetes mellitus,” Nutricion Hospitalaria, vol. 26, no. 6, pp. 1236–1241, 2011. [19] Z. Zeng, W. He, Z. Jia, and S. Hao, “Lycopene improves insulin sensitivity through inhibition of STAT3/Srebp-1c-mediated lipid Accumulation and inflammation in mice fed a high-fat diet,” Experimental and Clinical Endocrinology & Diabetes, vol. 125, no. 9, pp. 610–617, 2017. [20] M. Á. Martin, L. Goya, and S. Ramos, “Antidiabetic actions of cocoa flavanols,” Molecular Nutrition & Food Research, vol. 60, no. 8, pp. 1756–1769, 2016. 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Message ID: 218193205 (wp-p1m-39.ebi.ac.uk) Time: 2021/04/06 02:09:17 If you need further help, please send an email to PMC. Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_4zn3w52fgbahzbxgijrwkfkxem ---- 12 | P a g e HOAX LANGUAGE RHETORIC AND HATE SPEECH AS A PRINCIPLE REPRESENTATION OF DEMOCRATIC RIGHTS Author: Max Allan, Tony Williams, Shapier Moonches Published: Journal of Media Information and Science (2020) Vol. 22, Issue. 2 (pp. 12-22) Abstract: On the Internet, when you search for deceptive rhetoric or rhetoric hoax, you'll get more than two million hits for either one. That volume of hits is an echo of what we've heard all our lives---that Rhetoric is associated with deception and trickery, even though the college experts try to reassure us that the discipline of Rhetoric is really neutral. Fact is, though, most of what the public knows about Rhetoric is a hoax, especially as regards the origins, the history, and the confusion over Rhetoric in academic circles. Keyword: Hoax, Hate Speech, Democracy, Language, Pop Culture, Introduction The Origins of Rhetoric Most people, even school teachers, think the history of Rhetoric began in Greece with Aristotle but it didn't. In 427 A.D., sixty-year-old Gorgias, a sophist from the Greek colony of Leontini, in Sicily, brought Rhetoric to Athens. He settled in Athens and popularized rhetoric by offering public demonstrations of his skill in public speaking, which was his way of marketing his trade to anyone who wanted to learn to speak as he did. One of his most apt students, Isocrates, learned the trade and became "the most influential teacher of rhetoric in Aristotle's time" (On Rhetoric, Kennedy, George A., New York: Oxford University Press, 2006, p. 13). Why wasn't Aristotle "the most influential teacher of rhetoric" in his own time? Because he had his own personal brand of Rhetoric, and he taught it only to students in his small, private school in Athens, called the Lyceum. And his Rhetoric, really more of a collection of notes gathered over the years than anything else, was not 13 | P a g e published in his lifetime (384-322 B.C.) and was basically unknown outside his small, private school. In fact, not only was Aristotle's Rhetoric unknown in his own time, it was largely unknown and untaught throughout the ages. According to George A. Kennedy---a universally praised scholar of ancient Greek culture and a highly esteemed translator of Aristotle's Rhetoric---Aristotle's Rhetoric was "obsolete as a school text" throughout most of history (On Rhetoric, p. 308). Discussion The History of Rhetoric Aristotle's Rhetoric became obsolete because, first of all, it was lost in Asia Minor for about 200 years after his death in 322 B.C. out of circulation, out of usage, out of sight, out of mind. During that time, probably because it had no real competition, the Rhetoric of Isocrates flourished and became established as the major well-spring for progress in the art of Rhetoric. Also during that lost time, three very popular major features were added to Isocrates's Rhetoric that were never developed in Aristotle's version: · stasis (contributed to Rhetoric by Hermagoras of Temnos around 150 B.C.; a systematic series of questions used to develop the central issue in court cases) · tropes (one of two major divisions in figures of speech, see below; using words in a way that their normal meaning is replaced with something else, such as, "today the White House issued a statement"---as we know, the White House building did not issue the statement; irony is another example, such as when a sarcastic students says, "Yeah, I just loooove grammar") · figures of speech (the Stoic philosophers of Athens added these to Rhetoric somewhere between 250 and 100 B.C.; figures of speech are divided into two main categories: schemes and tropes; schemes change the ordinary or expected pattern of words, 14 | P a g e such as, "My voice teacher, a real looker," which uses the scheme of apposition or renaming; and tropes change the general meaning of words, as discussed in the entry just above). Scholars throughout history considered these three Rhetorical features as extremely important and studied and discussed them extensively. So they paid little attention to Aristotle's Rhetoric, which did not have them, after it was found and 'published' around 80 B.C. Then, around 190 A.D., Alexander of Aphrodesias published a commentary on Aristotle's Rhetoric, and scholarly interest revived a bit. However, throughout the Middle Ages and the Renaissance, the principal texts on Rhetoric were not Aristotle's, but two books that were based largely on the Rhetoric of Isocrates and its accompanying three supplementary features discussed above. These two books were Rhetorica ad Herrenium (Rhetoric for Herrenium), of unknown authorship, and De Inventione (On Invention), written by Cicero (106-43 B.C.), the great Roman philosopher, politician, and rhetorician. The modern academic and philosophic interest in Aristotle's approach to Rhetoric is often traced to the publication of philosopher Kenneth Burke's book, A Rhetoric of Motives, which was published in 1950. Since then, many other books have investigated and expounded upon Aristotle's Rhetoric, and more people today are reading and studying it than did so in all the rest of history combined. So the public perception that Aristotle's Rhetoric is the Rhetoric that was handed down and taught widely in schools throughout the ages is quite wrong. This hoax has been perpetuated by well-meaning but poorly educated textbook writers. The Confusion Over Rhetoric in Academic Circles Now, wouldn't you think that the actual bedrock principles of Rhetoric, the fundamental principles, would be pretty well-known and established after 2,500 years? And you would also think that an encyclopedia dedicated to collecting and explaining all the important parts, patterns, processes, purposes, and perspectives of Rhetoric would clearly identify and discuss them, right? Well, take a look at what the Preface says in the Encyclopedia of Rhetoric (New York: Oxford Press, 2001): 15 | P a g e [this is] our effort to abstract rhetoric as far as we could... and to endeavor to search for its principles. "Search for its principles"? Immediately following that eye-opener is this: We recognize the paradox, in view of what we take rhetoric to be. It is nearly impossible either to abstract a temporal cause from its effects or to look anew at a subject anchored in but not confined to an ancient tradition. But the attempt to do so, we believe, sets this work apart from other recent publications such as the Encyclopedia of Rhetoric and Composition.... [my bolding] I'm not even going to attempt to work out the "paradox" reasoning. But I wonder: Am I reading too much into this? Is Rhetoric as hard to define, is it as unstable and as unclear in what its old principles are and in what its new principles are, as this encyclopedia makes out? Let's try another encyclopedia dedicated to Rhetoric---there's only one other. Looking at the Preface to the Encyclopedia of Rhetoric and Composition (New York: Garland, 1996), we find: ... [this encyclopedia] provides an introduction to rhetoric, including the major periods and personages, concepts and applications. Rhetoric... is becoming ever more difficult to locate in a conceptual framework... many theorists are reconceptualizing rhetoric in its own terms. [my bolding] This encyclopedia of rhetoric "provides an introduction to Rhetoric"? Only an introduction? It doesn't go beyond identifying the very basic parts, pieces, and patterns of Rhetoric? Plainly, this encyclopedia is not claiming to be thorough and comprehensive, claiming that it covers only the basics, "an introduction." After 2,500 years of discussions and arguments about what Rhetoric is and what it is not, surely there should be more than just "an introduction" to Rhetoric in an encyclopedia dedicated to it! Is a more comprehensive version, which goes beyond this "introduction," in the works or being planned? No mention of that. Furthermore, "Rhetoric... is becoming ever more difficult to locate in a conceptual framework...." What?!!! There's that "paradox" sort of difficulty, again, as confessed by the first encyclopedia we discussed. Maybe it would have been helpful to explain what "conceptual framework" means. Perhaps it has something to do with identifying an overall pattern that organizes all the concepts of Rhetoric---"ever more difficult to locate," even now? 16 | P a g e The fact that "many theorists are reconceptualizing Rhetoric "in its own terms" clearly implies that theorists have not been conceptualizing Rhetoric in its own terms, for some reason. Why might that be? Let me take a shot at it---Perhaps it is because Rhetoric has so very many disorganized parts and pieces, without a clear hierarchical pattern of connections, that it's literally impossible to pin it all down into an organized pattern. In short, "rhetoric can mean nearly anything" (Professor George Pullman of Georgia State University; conference, What is the New Rhetoric? in Sydney, Australia, 2005) that an 'expert' wants it to be and says it is. Given what I've shown, here, that seems a decent interpretation of what was said in the prefaces to those two encyclopedias. So Rhetoric is definitely fair game for being compared to the saying, "You can't see the forest for the trees." Rhetoric has so many hundreds of devices and isolated concepts ("trees"), yet it has no clear, overriding principle ("forest") to hold them all together in a plainly recognizable pattern. Way back in 1663, the poet and satirist Samuel Butler said what many had said for centuries in more general ways and captured the spirit of this perennial confusion and uncertainty about Rhetoric with his famous, oft-quoted criticism: For all a rhetorician's rules teach nothing but to name his tools. Cute little saying, but Samuel Butler was serious. And so was Herbert Spencer (a very influential English philosopher of the Nineteenth Century, in Europe and America, in both literature and Rhetoric) when he said in his 1852 essay, "The Philosophy of Style," The maxims contained in works on composition and rhetoric are presented in an unorganized form. Standing as isolated dogmas---as empirical generalizations, they are neither so clearly apprehended, nor so much respected, as they would be were they deduced from some simple first principle. My take on what Spencer was saying is this: The many rules for writing and public speaking are not organized. If they were organized under a single, simple, powerfully unifying principle, then the rules of composition and rhetoric could be clearly understood, taught, and learned. 17 | P a g e A much more modern Rhetoric authority, the late Professor Wayne C. Booth of the University of Chicago, plainly agreed but went a little further than Spencer when he said, Where is the theory, where are the practical rules for ensuring that this talk will not only grab you, as the Madison Avenue rhetoricians say, but keep you grabbed and send you away determined to behave differently? (The Essential Wayne Booth, Wayne C. Booth & Walter Jost, University of Chicago Press: 2007, p. 69) Booth's point was that modern writing texts don't provide a comprehensive theory or practical rules for writing or speaking to a specific audience (neither did Aristotle's), and that Aristotle's Rhetoric couldn't fulfill our modern needs for "a rhetoric of the symposium, of the conference room," or of other modern situations that were not even imaginable in ancient Greece. Furthermore, there's been a whole host of Rhetoric authorities over the last one hundred and fifty years who have been simply clamoring for a "New Rhetoric"---because, like Booth, Spencer, and Butler, they see that Rhetoric simply can't handle the diversity, depth, breadth, and uniqueness of modern times. These authorities include a number of academic heavyweights: I. A. Richards, Kenneth Burke, Wayne C. Booth, W. R. Winterowd, Francis Christensen, James L. Kinneavy, E. D. Hirsch Jr., Andrea Lunsford, Lisa Ede, Richard Lanham, Reed Way Dasenbrock, C. H. Knoblauch, and Lil Brannon. So confusion reigns among modern encyclopedias dedicated to Rhetoric, and academic authorities have been complaining about the failings of Rhetoric for hundreds, if not thousands, of years. And they are all clamoring for something new-------because the old Rhetoric just isn't good enough anymore. The Hate Speech Manifesto The Western societies we live in today are socially, ethnically, and culturally diverse. Like most people, I believe the only way such a society can maintain its diverse nature is by being more tolerant and inclusive in regards to people from different backgrounds, cultures and also free speech and freedom of expression. In fact, the legal system protects the fundamental rights of each individual and also against any kind of hateful content that causes harm to us. 18 | P a g e Keeping these assertions in consideration, the willful dissemination of hatred - of what today's issues going on in the world definitely fall under - is untenable under our current understanding of hate speech and what is considered unjust. My central argument is not focused on censoring public discussion but on censoring hate and offering equal respect and avenues for all marginalized, stigmatized, and oppressed groups and what is best for our society. Thus, open hateful content not only causes dissemination of hate but the destruction of an inclusive society. There is no doubt that freedom of expression is the foundation of democracy. In fact, an individual's imagination and ability to express ideas and opinions makes us come closer to the truth and ensure a democratic society. However, certain limits need to be placed because with freedom of expression comes responsibility. Generally, hate speech is destructive not because of it being offensive, but because it silences the members of the minority group. For instance, when all Muslims are generalized as "terrorists," they feel damaged and threatened because they no longer feel a sense of belonging and part of a public debate. Another example is of how there are stereotypes attached to Black people being "criminals" or Indigenous women being a victim of rape, sexual abuse, and violence because according to our so-called "hero" Christopher Columbus, " they are barbaric or inhumane." This kind of hate speech convinces not only members of the larger community on how to view the target group but how the target group should view themselves. Therefore, the concern is not how such hateful content and speech on the Media or elsewhere harms an individual, but how the entire community and society is affected with a climate and aura of pure hatred. The logic and understanding behind hate speech and hatred content being problematic is that having the right to insult or offend certain religious beliefs and certain cultures inhibits the right to practice religion, inhibits the right to "blend in" a multicultural society, and inhibits the opportunity to create an inclusive society. If we can consider free speech and freedom of expression as core fundamental rights, shouldn't we consider freedom of religion, conscience, and thought as fundamental rights too? To ensure a democratic society? For a brief moment, let us assume that freedom of speech includes the right to offend. Yet, we should wonder if our 19 | P a g e compliance to celebrate "the right to offend" also extends to us reaching out in compassion to those who are offended or marginalized. Although it may not seem offensive to an outsider, they still give rise to understandable fear and insecurity. Hate speech and content against a particular group of people or race gives rise to consequences such as retaliation and violence. A thought-provoking point, therefore, is that the freedom to offend is not applied equally, but targets again and again communities that are already ostracized. It is important to understand that when we talk about fairness and equality, we should keep in mind that with fairness comes the idea of being sensitive to other people's differences. These differences play an essential role in shaping an individual's identity. Differences include culture, language, and religion. When it comes to free speech, equality, and expression, majority and the ones in power have the privilege to practice it. I believe that free speech should also be used as a tool by the minorities to shed light on injustice and that equality is the right way for them to augment their freedom and privilege they deserve. However, the notion of free speech and freedom of expression is violated when it comes to a certain group of people. This double-standard nature of freedom of expression and speech is visible when controversies and global issues arise. When we talk about the concept of co-existence we should inherit and meet halfway when a conflict is seen arising, not add fuel to the fire that already burns bright. We should not forget the purpose: which is focused on what is best for our society. By applying the difference approach (which is accepting and respecting people's culture, religion, and other differences), we are helping to understand why a particular practice or value is essential to a group's identity. Instead of asking the question of whether or not a particular group of people or individual has a right to practice a particular right or not and whether or not those practices violates a right or not, the difference approach weighs the history and scrutinizes the significance of a particular tradition or cultural/religious practice. It is important for the public to keep their biases and cultural misinterpretations aside about a particular group or race and expose problems by focusing their attention on how to understand, interpret, and assess identity-related claims. The main concern should be about 20 | P a g e fairness, justice, and equality - which each and every single individual/group is entitled to (freedom of speech, freedom of expression, and freedom of religion, conscience, and thought). Conclusion Add to all that, the 2002 report from the National Education Association that only one in five high school seniors can write well enough to do college work. No wonder the National Commission on Writing (NCW) declared in 2003 that there's a crisis in teaching writing in America! But what did the NCW recommend? The NCW practically demanded more time, more people, and more money be poured into the same old, ineffective writing instruction, without any basic changes to the fundamental principles that determine how writing is taught! (And, of course, what is taught in writing textbooks and writing classes across America is all based on Rhetoric. Rhetoricians are proud to point this out, by the way.) They want to spend a whole lot more money, time, and people on the same old thing that isn't working? As they say on Sesame Street, "What's wrong with this picture?" One last very telling point---Is there a final test that would either prove or disqualify Rhetoric as the basis for teaching writing? Yes, there is. It's called the What if test, and here it is: What if an essay or some other written work has all the pertinent forms of Rhetoric used perfectly in it? And what if it isn't new to the readers? If the reading audience DOES already know the ideas and is familiar with the presentation, then what's the point of that writing? Without being new, it has no audience. At the very least, it will be oppressively boring to readers. If it's a book intended for public distribution, it won't see the light of publishing day--- people don't put out good money for old news, and publishers know that very well. Ditto for poetry, short stories, essays, and especially journalistic articles, opinions, and editorials. 21 | P a g e And the Rhetoric of Isocrates, the Rhetoric of Aristotle, the Rhetoric of Cicero, the Rhetoric of Quintilian, the Rhetorica ad Herennium, James L. Kinneavy's Theory of Discourse--- not one of them develops a step-by-step process for generating the astonishingly simple but amazing ignored concept of What's new to the reader We don't need a New Rhetoric. We need a Rhetoric of Newness. In conclusion, I believe that the values of free speech and freedom of expression are misunderstood. They are regarded as intrinsic and instrumental in nature because of our individualistic understanding of them as opposed to a collective understanding. By adapting to the difference approach and also the idea of social consensus, we will be enhancing an inclusive environment. By including the people who are the subject of the debate (whether they are Muslims, Non-Muslims, Jews, Christians, etc) we aim for respectful tackling of controversy - an approach in which we do not make enemies. Therefore, it is important to note that public discourse is not just about what is fair and what is true, it is also helps us develop our preferences and choices. These preferences are not prosaic and dominant in nature but dependent on public debate which is inclusive of all majority and minority. As a result, we should be able to observe how hate, in its pure form, does nothing but disintegrate the vulnerable member's of the society's dignity and does not serve to further the ambitions of freedom of expression and speech. References Aldyan, R. A., Warto, W., & Marimin, M. (2019). " Ngalab Berkah" on the Tradition to Open Luwur the Sunan Kudus Tomb. International Journal of Multicultural and Multireligious Understanding, 6(4), 156-165. Alisa, F., & Ridho, Z. (2020). Sustainable Cultural Tourism Development: A Strategic For Revenue Generation in Local Communities. Journal of Economic and Tropical Life Science , 4(2). https://doi.org/10.21428/e61c265e.f512dbd8 Brown, A., & Sinclair, A. (2019). The politics of hate speech laws. Routledge. Bossaller, J., Bernier, A., McQueen, S., & Peterson, M. (2019). The hoax and the president: Historical perspectives on politics, truth, and academia. Political economy of the information society. https://doi.org/10.21428/e61c265e.f512dbd8 22 | P a g e Carr, P. R., Sanchez, S. L. C., & Daros, M. A. (2020). Citizen Engagement in the Contemporary Era of Fake News: Hegemonic Distraction or Control of the Social Media Context?. Postdigital Science and Education, 2(1), 39-60. Crane, J., Barthow, C., Kang, J., Hood, F., Stanley, T., & Wickens, K. (2019). Probiotics for humans: hoax, hype, hope, or help. Journal of the Royal Society of New Zealand, 1-14. Denton Jr, R. E., Trent, J. S., & Friedenberg, R. V. (2019). Political campaign communication: Principles and practices. Rowman & Littlefield. Diepeveen, L. (2019). Modernist Fraud: Hoax, Parody, Deception. Oxford University Press. Dewi, E. W., Drajati, N. A., & Yunus, M. M. (2019). Exploring Intonations in Sesame Street’s Puppet Shows: A Phonological Perspective. Issues in Language Studies, 8(2), 32-47. Farkas, J., & Schou, J. (2019). Post-truth, Fake News and Democracy: Mapping the Politics of Falsehood. Routledge. Fish, S. (2019). The First: How to Think About Hate Speech, Campus Speech, Religious Speech, Fake News, Post-Truth, and Donald Trump. Simon and Schuster. Habibi, H. (2018). Protecting National Identity Based On The Value Of Nation Local Wisdom. International Journal of Malay-Nusantara Studies, 1(2), 24-40. Heinze, E. (2019). An Anti-Liberal Defense of Free Speech: Foundations of Democracy in the Western Philosophical Canon. Howell, A. R. (2019). Politics, Memes, and Culture Jamming: Meme Culture’s Potential to Engage Youth in Politics. Littlewood, K. (2019). The Big Estrogen Hoax. Endocrinology. Maerz, S. F. (2019). Simulating pluralism: the language of democracy in hegemonic authoritarianism. Political Research Exchange, 1(1), 1605834. McManus, M. (2020). Post-modernism as Philosophy and Post-modernism as Culture. In The Rise of Post-Modern Conservatism (pp. 19-44). Palgrave Macmillan, Cham. Nusbaum, H. C. (2019). The Breakdown of Civic Virtues and the Problem of Hate Speech: Is There Wisdom in Freedom of Speech?. In Applying Wisdom to Contemporary World Problems (pp. 111-142). Palgrave Macmillan, Cham. Poole, A. (2019). Democracy, Rights and Rhetoric in Southeast Asia. Springer. Sellnow, T. L., Parrish, A., & Semenas, L. (2019). From Hoax as Crisis to Crisis as Hoax: Fake News and Information Disorder as Disruptions to the Discourse of Renewal. Journal of International Crisis and Risk Communication Research, 2(1), 6. Stengrim, L. A., & Knight, G. B. (2019). Rhetorics of Resistance in a World of Fake News. Alternative Media Meets Mainstream Politics: Activist Nation Rising, 199. Sparke, M., & Bessner, D. (2019). Reaction, Resilience, and the Trumpist Behemoth: Environmental Risk Management from “Hoax” to Technique of Domination. Annals of the American Association of Geographers, 109(2), 533-544. work_57vzqqf6ujgthk2bpwleymetby ---- Iperstoria – Testi Letterature Linguaggi www.iperstoria.it Rivista semestrale ISSN 2281-4582 Saggi/Essays Issue 6 – Fall 2015 299 Stefano Bosco 1 MARITIME RESERVATIONS: HARBORING INDIGENOUS AMERICA IN GERALD VIZENOR’S THE HEIRS OF COLUMBUS 2 Written and published in concomitance with the 500 th anniversary of Columbus’ arrival in America, The Heirs of Columbus is a prime example of Vizenor’s ability to reinvent history using humor and imagination. For those not very much familiar with him and his works, a few introductory notes may help. Of mixed Swedish- American and Ojibway/Anishinaabe ancestry, Vizenor is one of the major figures in contemporary Native American literature and intellectual life: novelist, poet, essayist, university professor, he is also an enrolled member of the Minnesota Chippewa Tribe on the White Earth Reservation. He is probably the writer that has most actively engaged the language and politics of postmodernism to put it at the service of indigenous people’s cultural expression, starting with his first novel Darkness in St Louis Bearheart (1978). He is the inventor of neologisms and concepts that have become common currency in Native American Studies, such as for example the idea of survivance (a sort of proactive, anti-victimizing approach to survival) or the notion of postindian (which he adopted to contrast the simulation and falsification embodied by the signifier Indian, seen as a heritage of the colonial domination of indigenous America). Rejecting a static and fixed notion of Indian identity, he has elaborated a cross-blood (mixed-blood) aesthetics based on the liberating potential of trickster discourse—the trickster being the destabilizing and shapeshifting half-human, half-animal figure so crucial in Native American and particularly Ojibway mythology and folklore. All of these aspects have a part in The Heirs of Columbus, and my exploration of the harbor theme cannot do without a consideration of the larger implications of this novel for the development of contemporary Native American literature. A first element to highlight is the work’s intertextual dimension: the novel is full of references to real and imaginary texts belonging not only to the Euro-American tradition (think of the numerous quotes from Columbus’ logbooks) but also to the Native American (Anishinaabe in particular) oral and written traditions—which can be seen for instance in the choice of character names that sometimes recall those of Native and non-Native fictional or real-life figures. As James Cox pointed out, such contextualization of the novel within the American Indian cultural tradition “helps liberate characters, and Vizenor’s readers, from non-Native traditions that present a single colonial plot of Eurowestern superiority and inevitable violence and conquest” (125). Overall, Heirs is a satirical re-writing of the Columbian master narrative that counters the historical concept of discovery and the consequent subjugation of indigenous people, by transforming it into a return to indigenous sources of knowledge and existence, inspired by the healing power of stories and aimed at a continuation of Indian sovereignty on the American continent. 3 Columbus is imagined by Vizenor as a man of mixed Mayan and Jewish ancestry; such genealogy weaves together the historical (though unfounded) belief that American Indians descended from the lost tribes of Israel with the imaginary notion that the Mayans had actually travelled to Europe long before the time when Europeans encountered their civilization in central America (right in the wake of Columbus’ arrival in the 1 Stefano Bosco (stefano.bosco@univr.it) received his MA at the University of Padua and is now completing a PhD in American Studies at the University of Verona. His dissertation project focuses on Native American literature and in particular on early-20th-century fiction by native authors. Among his other research interests are 19th-century classic American literature, the memory of slavery in literature and film, American cinema and its distinctive genres, literary and film theory and criticism. He has published essays and reviews both in English and in Italian on topics such as Native American literature, the American Western, 19th-century American authors. 2 This piece constitutes a slightly longer version of a talk I gave at the latest AISNA Biennial Conference, which took place in Naples, 24-26 September 2015. The theme of the conference revolved around the idea of ‘harbor’ with its various declinations and connections (e.g. the issue of immigration) across the various fields of American Studies—including primarily literature, history, and visual culture. 3 Taiwanese scholar Iping Liang has provided an interesting analysis of the novel by discussing Vizenor’s technique of “oppositional play,” which articulates a tribal-centered “discourse of encounter in the comic and communal sign of the trickster figure of Admiral Columbus” (124), as a form of tribal resistance against the tragic consequences of the real history of encounter. Iperstoria – Testi Letterature Linguaggi www.iperstoria.it Rivista semestrale ISSN 2281-4582 Saggi/Essays Issue 6 – Fall 2015 300 continent). Columbus’ voyage is thus reconfigured as a return to a homeland distant in time more than in space. The historical motivations behind the expedition are here replaced by Columbus’ hearing of stories carried “in the blood” which inexorably attract him to a world that is actually older than Europe and contributed to establish its supposedly superior ‘civilization.’ According to Vizenor’s narrative, upon his arrival in the Bahamas islands, Columbus meets and copulates with Samana, a shaman figure alternatively described as a “hand talker,” a “silent tribal wanderer,” a “golden healer,” and a “cross-blood black bear” (4, 10, 12): from that “primal union” (20), the heirs of Columbus start spreading across the New World, and Samana continues to re-appear among the heirs to heal with the stories and with a blue radiance as she first did with the great explorer. Of course, the heirs of the title are the present-day (1990s) descendants of Columbus and Samana; they constitute a sort of enlarged, bizarre family, where the confines between animal and human, natural and supernatural, are often unclear, in line with Vizenor’s trickster universe. At the beginning of the novel, they reside at the headwaters of the Mississippi, along the shores of Lake of the Woods in the Northwest Angle exclave between the United States and Canada; here, they have anchored a pleasure barge named after Columbus’ main caravel, The Santa María Casino, where they play bingo and other games of chance that guarantee them economic prosperity and constitute the economical basis of their sovereigntist claims. Right beside the Santa María there’s also the Niña, a barge-restaurant, and the Pinta, a tax-free market. Through this ironical re-imagining of the famous Columbus’ caravels, Vizenor re-appropriates “a master symbol of Euroamerican history” (Owens 101) from a Native American perspective, and transforms the epic of European discovery into an affirmation of Indian sovereignty in the contemporary scene. To do so, Vizenor has to engage with the authority of legal discourse that has characterized the relations between the US government and Indian tribes for centuries, and that has almost always relegated indigenous people into a subordinate position as subjects incapable of ruling themselves. At the beginning of the novel, for example, we are told that Stone Columbus, the oldest of the heirs and host of the bingo barge, had been arrested for violating state tax and gambling laws, but was subsequently released when a sympathetic federal judge ruled that “the Santa Maria and the other caravels are limited sovereign states at sea, the first maritime reservations in international waters” (7-8). Court hearings like this occupy center stage throughout the novel, especially when the heirs set out to repatriate the remains of Christopher Columbus and Pocahontas back to the newly-established Indian nation, and encounter the resistance of white museum directors and other obscure forces—a point I will briefly refer to later on. It is clear that the water element is not inconsequential to Vizenor’s elaboration of the harbor-as-sovereign- reservation metaphor. As the same judge who ruled in favor of Stone Columbus proclaims, “the notion of tribal sovereignty is not confiscable, or earth bound; it is neither fence nor feathers. The essence of sovereignty is imaginative, an original tribal trope, communal and spiritual, an idea that is more than metes and bounds in treaties” (7). 4 This quote articulates in highly imaginative terms what is Vizenor’s creed regarding the highly debated idea of Indian sovereignty: not a fixed, static reality that can be appropriated and usurped, and even less something that can be appraised or measured according to a western-centered anthropological or legalistic discourse, but something that, water-like, continually flows through the spirit and body of the community without being easily separated or isolated from it, and that is continually nurtured by the power of the imagination. In particular, imagination is what allows Native people (and human beings in general) to think differently of history and its traumatic events, and to produce alternative scenarios that reject the imposed narratives of European conquest and white superiority, in order to better sustain native communities in their dealing with past, present, and future challenges. This is exactly the kind of operation Vizenor pursues through The Heirs of Columbus, i.e. a liberating narrative that runs counter to the official histories of Euroamerican discovery and possession of indigenous land (and sea), and that at the same time, by means of scathing humor and satire, may heal indigenous people from the malady generated by a century-long colonial oppression. As Kathryn Hume has argued, “another function of the imagination is to guard us against a fatal attraction of terminal creeds” (131), an expression that Vizenor coined to describe, 4 In another passage of the novel, a character proclaims that “the notion of sovereignty is not tied to the earth, sovereignty is neither fence nor feathers,” and that “the very essence of sovereignty is a communal laser” (62). Iperstoria – Testi Letterature Linguaggi www.iperstoria.it Rivista semestrale ISSN 2281-4582 Saggi/Essays Issue 6 – Fall 2015 301 using James Cox’s terms, “the systems of belief that oppress the human imagination and justify the many manifestations of colonial violence” (137). I would argue that it is precisely the peculiar topography of the harbor what allows Vizenor to resist the kind of colonial discourse that the heirs are so dedicated to overturning. Envisioning a sovereign Indian nation on a land reservation would not have sounded equally subversive, and perhaps it would have risked reiterating the masterful image of confinement with “fence and feathers” that is historically sanctioned by the federal establishment of the reservation system. Imagining a sort of unhistorical, or anti-historical maritime reservation, instead, Vizenor circumvents the disempowering limitations of official history while playing at the same time with the aquatic imagery of the Columbian discovery. The tribal nation established by the heirs, however, is not what one would be tempted to describe as a utopian formation: on the contrary, the maritime reservations/nations Vizenor describes occupy specific geographical locations, whose geopolitical nature bespeaks the senselessness of Euro-American partitioning of the continent but also the Indians’ ability to carve out a space of resistance and to promptly claim their territorial rights on the land of the ancestors. I just used the plural ‘reservations’ since I have not specified yet that in the novel the heirs move from one maritime reservation to another, with the latter being a more solid continuation of the former: when the Santa Maria Casino sinks due to a violent storm on Lake of the Woods, the heirs travel westward to establish another, even more impressive sovereign harbor at Point Roberts in Washington State, which they rename Point Assinika, the “place of stones.” 5 Similarly to the Northwest Angle exclave, Point Roberts too has a peculiar characteristic: it rests on a strip of land that is physically separated from the United States, since it borders Canada and the waters of Boundary Bay, but belongs to the US given that its latitude is below the 49 th parallel (the Northwest Angle, instead, is the only place outside Alaska lying north of the parallel). By choosing such peculiarly-situated areas as the headquarters of the heirs’ tribal nations, Vizenor playfully evokes the tragic history of Euro-American encroachment on Native land and its splitting among colonialist national powers (the US and Canada) by means of treaties that flagrantly ignore the presence of indigenous people on the continent. But the power of his invention goes farther than that: in a sense, what is here being challenged is the Euro-American arrogant certainty that Native tribes have been definitely confined to enclosed spaces and that they can no longer constitute a menace for the territorial wholeness of either the United States or Canada. Inhabiting such interstitial, border-line spaces that are generally overlooked by the big Anglo-American nation states, the heirs pose themselves as a subversive and destabilizing presence, though their main commitment now is not to violent conquest but to the act of healing with storytelling, games of chance, genetic research. In addition, the fact that in both cases (at the Mississippi headwaters in Minnesota and at Point Roberts in Washington) the heirs’ sovereign nations are essentially harbor/marine terminals, occupying inter-national waters between land and sea (or lake), is instrumental to Vizenor’s creative elaboration of the Columbian myth: after all, upon his arrival in the Caribbean sea, the great admiral was indeed crossing what we may term ‘inter-national’ waters, if we think retrospectively (but coherently with the present-day struggle of indigenous people) of pre-Columbian America as peopled by sovereign native nations. In addition, the water element suggests the fluidity of indigenous notions of place, which is not a static figuration on a map but a presence living in tribal memories and tribal stories. As Vizenor stated in an interview included in his book Postindian Conversations, referring specifically to his imagining of Point Assinika, “the creation of a native place is in the memory of the story;” places are remembered and continued through stories that engender their creation as if “out of water,” since for Vizenor “we are water, and there is no presence without water and trickster stories of that creation” (135). Besides turning the Genoese explorer into a cross-blood tribal trickster and the trope of discovery into a much-awaited homecoming, the novel also provides, more specifically, a revision of the mythology of US freedom and exceptionalism from a tribal perspective. Namely, what the heirs accomplish throughout the narrative can be seen as a re-staging of the Slotkinian idea of ‘regeneration through violence’ in the form of a ‘re-generation through healing,’ whereby the very word ‘regeneration’ assumes an additional value by merging the act of generating with the idea of descent from a common ancestor (i.e., Columbus). And once again, the harbor imagery is very effective in illustrating this point. The sinking of the Santa Maria Casino in a thunderstorm at Lake of the Woods, for example, clearly recalls the running ashore of the real Santa Maria 5 Stones and stone-related images recur throughout the novel to symbolize ideas of birth and regeneration according to a specific tribal (Ojibway) account of creation stories. See Liang 134-135. Iperstoria – Testi Letterature Linguaggi www.iperstoria.it Rivista semestrale ISSN 2281-4582 Saggi/Essays Issue 6 – Fall 2015 302 caravel in late December 1492—an event which gave origin to the first European settlement in the Americas, La Navidad. But in the context of Vizenor’s satirical revision of the Columbian myth, the casino’s shipwreck may also stand as a reprimand against the danger of reiterating the European greed for the New World riches. As James Cox argued, the activities taking place in the casino barge (which he defines as “gambling on maritime explorations in search for treasures,” 131) figuratively associate Stone Columbus’ tourists and casino attenders with Christopher Columbus’s sailors and the Spanish monarchs funding his expedition. However, when later in the novels the heirs decide to establish another maritime reservation at Point Roberts, equipped with yet another casino, they ground it more decidedly on healing and communal liberation rather than, as the shipwrecked Santa Maria sailors did, on the personal accumulation of riches and the search for gold. In addition, once settled at Point Roberts, the heirs place a giant copper statue on the shore near the marina and name it “the Trickster of Liberty.” Higher than the Statue of Liberty and facing west instead of east, the statue also bears an inscription that promises “to heal the tired tribes and huddled masses yearning to breathe free” (122): as is well-known to American readers, these words are an almost exact replica of those found on the pedestal of the Statue of Liberty in New York harbor, taken from Emma Lazarus’s sonnet. But rather than being presented as a protective, maternal figure for the (generally white) immigrants seeking refuge in the New World, the heirs’ statue stands out as a tribute to the healing power of American Indian tribal humor, visually reinforced by the attributes of the trickster figure, as the numerous references to its being “crotch high” testify. Moreover, differently from the kind of imagery usually evoked by the Statue of Liberty, the trickster monument announces the entrance into a nation that rejects the regulatory and disciplinary practices of the western nation states: Point Assinika is indeed described as a “free state with no prisons, no passports, no public schools, no missionaries, no television, and no public taxation” (124), whose primary commitment is healing through “genetic therapies, natural medicine, bingo cards, and entertainment.” The commitment to healing and trickster stories runs counter to the arrogance and violence of what Vizenor terms a “monotheistic chemical civilization” (Vizenor and Lee 129) that has been poisoning and ravaging the American continent since the time of Columbus’s first landing. 6 As several scholars have noted, moreover, the establishment of Point Assinika as a sovereign nation is interwoven with the Ojibway creation myths, lying outside the exclusively legal-political framework through which a Euro-centered perspective may read that accomplishment. Besides liberating Native people from the entrapping narratives of European emigration and discovery (Cox 139), then, the novel successfully commits itself to write history anew in a way that is respectful to native presence and informed by native beliefs in the American continent. A few words need to be said about another crucial subplot in the novel, i.e. that revolving around the repatriation of the Christopher Columbus and Pocahontas remains. Their ashes need to be protected from the greedy hands of what Vizenor calls “bone barons,” i.e. white anthropologists, scientists, or collectors that steal tribal remains for purely scientific purposes or, even worse, for profit and exhibition: in their hands, the stories of the dead are turned into “academic chattel” inside museums or other sites that symbolize white exploitation of indigenous history. The ashes are also important to the heirs in that they carry the “genetic signature of survivance” (33), the phrase Vizenor employs to indicate the regenerative power of tribal memories and knowledge for the survival of future generations. In the novel, it is Stone’s wife Felipa Flowers that is especially committed to the repatriation of the bones: Vizenor describes her as “a tribal liberator who poached tribal remains from museums to atone for the moral corruption of missionaries, anthropologists, archaeo-necromancers” (50). First, she manages to steal the Columbus remains along with other sacred medicine pouches from a New York museum thanks to the aid of a teleporting trickster shaman, and subsequently wins the lawsuit filed against her by the cunning museum manager. Then, to recover the 6 Examining the crucial fact of Vizenor’s battle against harmful colonial representations through other representations (though in the interest of indigenous people), Stuart Christie points out the novel’s regrettable overlooking of extant tribal survival and resilience: “Vizenor’s rewriting of Assinikan cultural and geographic space, as it so happens, is also an overwriting of the oral, trickster tradition of the coastal Salish peoples who have historically inhabited not ‘Assinika’ (…) but Chelh-ten-em, translated from coastal Salish as ‘the place where one hangs salmon to dry’” (113). For Christie, such failure to account for the existing tribal presence in the area “across which Vizenor maps his liberated Assinikan nation, casts a long shadow across his powerful articulation of trickster potential.” Iperstoria – Testi Letterature Linguaggi www.iperstoria.it Rivista semestrale ISSN 2281-4582 Saggi/Essays Issue 6 – Fall 2015 303 Pocahontas ashes she has to travel overseas in England, where a book collector helps her locate them in the cemetery of an old parish church near London; however, before she can grab the ash casket, she is killed by a mysterious murderer who will turn out to be the director of the New York museum. By the end of the novel, after the arrest of the villain, the remains of Pocahontas will eventually be delivered by the London antiquarian at the new nation at Point Assinika, where they join those of Columbus in order to be “sealed in vaults at the House of Life near the base of the Trickster of Liberty” (174). 7 With the sealing of Columbus and Pocahontas ashes in a sort of “trickster shrine,” the heirs have completed their mission of turning these two cultural icons from emblems of the epic of discovery and the submission of indigenous people by Euro-American powers into living tribal ancestors to be treasured by the entire community. By playing humorously with both history and myth, Vizenor’s novel has revised the master narrative of domination and exploitation that shaped for centuries the dominant understanding of American history, and that still characterized prominently the 1992 Columbian Quincentenary celebrations. In James Cox’s words, “the political currency of the novel derives from the liberatory humor, not from the possibility that the story itself will become a new master narrative of dominance” (129). While The Heirs of Columbus is a comical attack against the ways those official accounts of history have perpetuated the oppression of indigenous people, it is also a serious invitation to use the liberating power of imagination and trickster humor to dismantle the authority of those narratives and envision a brighter future for indigenous people and their communities. Works Cited Christie, Stuart. Plural Sovereignties and Contemporary Indigenous Literature. New York: Palgrave Macmillan, 2009. Cox, James. Muting White Noise: Native American and European American Novel Traditions. Norman: University of Oklahoma Press, 2006. Hume, Kathryn. “Gerald Vizenor on Imagination.” The Native American Renaissance: Literary Imagination and Achievement. Eds. Alan R. Velie and A. Robert Lee. Norman: University of Oklahoma Press, 2013. 129-143. Liang, Iping. “Opposition Play: Trans-Atlantic Trickstering in Gerald Vizenor’s The Heirs of Columbus.” Concentric: Studies in English Literature and Linguistics 29.1 (2003): 121-141. Owens, Louis. Review of The Heirs of Columbus, by Gerald Vizenor. American Indian Quarterly 17.1 (1993): 101-102. Vizenor, Gerald. The Heirs of Columbus. Middletown: Wesleyan University Press, 1991. Vizenor, Gerald, and A. Robert Lee. Postindian Conversations. Lincoln: University of Nebraska Press, 2003. Weaver, Jace. The Red Atlantic: American Indigenes and the Making of the Modern World, 1000-1927. Chapel Hill: The University of North Carolina Press, 2014. 7 Liang has interestingly discussed the trans-Atlantic exchanges that characterize the novel, and that are visible not just in the obvious ‘detective-story’ subplot, but also in the re-figuring of the Great Admiral as a Sephardic Jew (136-137). From this perspective, The Heirs of Columbus is a work that perfectly fits Jace Weaver’s paradigm of a ‘Red Atlantic’ (literary) imaginary spanning more than five centuries, from the accounts of Columbus and his contemporaries to the postmodern revisions of American Indian history and experience by writers like Vizenor (see Weaver, especially chapters 1 and 5). work_5dyh2nqtjnhs7hdu3hrydy7ctm ---- wp-p1m-38.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-38.ebi.ac.uk no 218202157 Params is empty 218202157 exception Params is empty 2021/04/06-02:09:28 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. Message ID: 218202157 (wp-p1m-38.ebi.ac.uk) Time: 2021/04/06 02:09:28 If you need further help, please send an email to PMC. Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_5fyixhflgje2zpmxjlca4e2eki ---- Obituaries 69 Obituaries Colin Bertram, British polar explorer, biologist, and former director of the Scott Polar Research Institute, died at his home in Graffham, Sussex, on 11 January 2001, aged 89. Born on 27 April 1911, George Colin Lawder Bertram showed early interest in natural history. In 1932, while reading zoology at St John's College, Cambridge, he and fellow undergraduate David Lack organised the Cam- bridge expedition to Bj0rn0ya, undertaking ornithological studies and collections. The next year, as a member of the three-man Cambridge expedition to Scoresby Sound, he was transported to East Greenland by the celebrated French explorer J.-B. Charcot, in his equally celebrated expedi- tion ship Pourquoi-Pas?, a remarkable experience for an aspiring polar biologist. After a brief spell studying coral reefs in the Red Sea, in 1934 Bertram joined the British Graham Land Expedi- tion, initially as a marine biologist with the ship's party, later replacing Brian Roberts in the shore party. One of a series of non-governmental, low-budget, but strikingly efficient expeditions that characterised post-'Heroic Age' British polar exploration, the BGLE gave Bertram many opportunities to learn polar craft, including sailing, dog- sledging, and surveying, from friendly experts only a little older than himself. There were also opportunities for a young biologist to make his mark. The 16 men and 80-100 sledge dogs relied heavily on seals for food: Bertram studied the seals as they were killed, writing his conclu- sions in a scientific report and a thesis that earned him a Cambridge PhD. He was awarded also the Polar Medal and the Bruce Memorial Medal of the Royal Scottish Geographical Society. Bertram later told his experiences in 'Antarctica sixty years ago: a re-appraisal of the British Graham Land Expedition 1934—1937,' which was pub- lished as a complete edition of Polar Record (32 (181): 9 8 - 183 (April 1996)). In 1939 Bertram married Kate Ricardo, a fellow gradu- ate in zoology. In the same year he wrote Arctic & Antarctic: the technique of polar travel. During the early months of World War II, he was involved in War Office research on Arctic clothing, which included designing and testing early versions of the string vest. From 1940 he joined the Colonial Office, becoming chief fisheries ad- viser in Palestine, later fisheries adviser to the Middle East Supply Centre in Cairo. After the war Bertram returned to Cambridge, taking up a fellowship and tutorship at St John's and immersing himself in college administration and raising four sons. From 1949 he held the part-time appointment of director of the Scott Polar Research Institute, a prestigious but chroni- cally under-funded institution that made little use of his polar knowledge and skills. Before retiring on 31 Decem- ber 1956, he was instrumental in ensuring that his succes- Fig. 1. Colin Bertram when he was director of the Scott Polar Research Institute. sor would hold a full-time directorship. In the following year Bertram was awarded the Murchison Grant of the Royal Geographical Society and held a visiting professorship at the University of Otago, New Zealand. In 1965 he became senior tutor atStJohn's, an appointment he held until 1972. College life, research on a diversity of practical ecological issues from tropical fisheries and manatee conservation to fur seals of the Pribilof Islands, coupled with long-term involvement in the affairs of the Royal Geographical Society and the Eugenics Society, kept his life busy well beyond formal retirement. Apart from research papers, Bertram wrote Adam's brood: hopes and fears of a biologist (1959), In search of mermaids: the manatees of Guyana (1963), Antarctica, Cambridge, conservation and population: a biologist's story (1987), and Memories and musings of an octogenar- ian biologist (1992). Kate Bertram, who from 1970 to 1979 was president of Lucy Cavendish College, Cam- bridge, died in 1999. Bernard Stonehouse 70 OBITUARIES Helge Ingstad, Norwegian scholar, sailor, adventurer, and writer, died at his home in Oslo on 29 March 2001, aged 101, ending a life spanning three centuries. He discovered the only authenticated Norse ruins in North America. His study of the Icelandic sagas and of other medieval documents, and his knowledge of weather, sea- ice conditions, and early navigation techniques had guided him in his long quest in the wake of Eric the Red and the Norse explorers of a thousand years ago. In 1953 Ingstad and his wife Anne-Stine (Moe), an archaeologist, had examined ruins of Norse settlements in West Greenland. As a result, they recognized the need to search for further Norse remains along the Labrador and Newfoundland coasts. In the summer of 1960, after sailing from Norway in his own ship Halten with a crew of six, Ingstad made a preliminary survey of these coasts from ship and light aircraft. In the following spring, sailing out of Montreal and accompanied by his wife, he followed the north shore of the St Lawrence River, and then the coast- line northeastwards, examining likely locations for Norse settlements. Finally, near the northern tip of Newfound- land and on its eastern side at L'Anse aux Meadows, his attention was drawn by a local man, George Decker, to some grassy mounds that Ingstad recognized as possible remnants of Scandinavian sod houses. His hunch was proved correct from excavations directed by his wife in the 1961 summer and in seven subsequent summers. Her archaeological finds included the foundations of eight buildings, including a large house almost identical to Leif Ericsson's 'great hall' in Greenland; an area used for smelting bog iron; and artifacts such as a soapstone spin- dle-whorl and a bronze tunic pin of Norse design. The radiocarbon method gave the date of the site as about 1000 AD, according with that indicated in the sagas for the main winterings in Vinland. The Ingstads thought it more than probable that L'Anse aux Meadows was the place referred to in the sagas as 'Leifsbudir.' After 1968 the Ingstads left further excavations to Parks Canada, but kept a close eye on L' Anse aux Meadows, which, in 1980 to their delight, was named by UNESCO as an official World Heritage Site. Historical tourism at the site has helped to offset the severe damage to the economy of the region caused by the ban on cod-fishing in Newfoundland's coastal waters, imposed by the Canadian government in 1992. Helge Marcus Ingstad was born on 30 December 1899 at Meraker, near Trondheim, where he enjoyed a hardy upbringing among the mountains. After taking a law degree in 1922, he worked for four years as a lawyer, before embarking on a life of adventure and research. In 1926-30, he worked as a fur-trapper in northern Canada, and there acquired a lifelong interest in the Arctic, which he was able to indulge in a series of privately organized expeditions, with the emphasis on ethnography and archaeology. He wrote up his travels and research in a long series of popular books and scholarly papers. His Canadian experience is recorded in Land of feast and famine (1933), dealing with the region of Great Slave Lake and the upper Thelon River. His expedition to East Greenland, 1932-34, isdescribed'm East of the great glacier(\937). From 1936 to 1938, he served as a district judge in Svalbard, and became an authority on the history and development of those Arctic islands. After the war, Ingstad resumed his travels with an expedition to northern Alaska, 1949-50, to study the Nunamuit Inuit of the Brooks Range, of whom he published an account in Nunamuit (1952). His visits to Norse sites in West Greenland in the 1950s were described in Land under the pole star (1966), and a popular account of his great discovery in Newfoundland is contained in Westward to Vinland (1969). Finally, Ingstad and his wife set the seal on their work in Newfoundland with the publication by the Oslo University Press of The Norse discovery of North America (1986, two volumes), containing a full report on the excavations at L'Anse aux Meadows. Ingstad was recognized in his own country as a Knight of St Olav, Honorary Doctor of Oslo University, and Fridtjof Nansen Medalist. Other honours came to him, including the Andree Medal of the Royal Swedish Geographical Society, and honorary doctorates from the University of Calgary, McGill University, and Memorial University in Canada. Finally, in 1991, jointly with his wife, he received the Founder's Gold Medal of the Royal Geographical Society, a belated award but one that he greatly prized. He must have been the oldest recipient of a Royal medal from that Society; in his quiet and modest way, he took a wry pleasure in receiving it in the year before the quincentennial celebrations of the official discovery of North America by Christopher Columbus. Anne-Stine, for 56 years his devoted wife and co- worker in the field, died in 1997, aged 79 (Polar Record34 (190): 273 (1998), and Ingstad is survived by their daughter and grandchildren. Geoffrey Hattersley-Smith Pyotr 'Peter' Typykhkak, chairman of the Association of Traditional Marine Mammal Hunters of Chukotka (for- merly known as the Union of Marine Mammal Hunters), died of complications associated with stomach cancer on 9 December 2000 in the village of Sireniki, Provideniya Region, Chukotka Autonomous District, Russia. Typykhkak was born in 1933 in Imtuk, a settlement near Sireniki. His Eskimo name was Typykhkak. Typykhkak spent most of his life in Sireniki. When he was 15 years old he was already an assistant marine mammal hunter on the schooner Oktober. He spent his entire career at sea, and, in addition to being a leading traditional marine mammal hunter, he also worked in the Soviet state system, working his way up from shooter, to motor-man, and then to brigadier (whaling crew captain). Although partially blind in one eye, he was a good shot. He was widely considered one of the most respected elders, and he spent much time teaching young hunters in Chukotka. Typykhkak was active in civic life and served as a deputy OBITUARIES 71 (legislator) in village, regional, and district government. He was a member of the Magadan Regional Party Commit- tee. Typykhkak particularly showed his wisdom and talent as a leader after the collapse of the Soviet Union. As the old restrictions melted away, he became extremely active in bringing his people and his organization in close contact with the people of St Lawrence Island, and of northwest and northern Alaska. He forged very close alliances with the Alaska Eskimo Whaling Commission, the North Slope Borough, the Alaska Nanuuq (polar bear) Commission, the Eskimo Walrus Commission, and other native hunting organizations. He was committed to renew the traditional bowhead whale hunt for the Chukotka native people. Typykhkak had been on the last bowhead whale hunt allowed by the Soviet government in 1972. He related that on his wife's deathbed she asked to taste, one last time, some bowhead wha\e muktuk, which he was not able to give her. In 1996, standing on the beach in front of his village, he pressed a delegation from the Alaska Eskimo Whaling Commission and the North Slope Borough about what he could do to renew the traditional bowhead whale hunt. His persistence led to a long process that involved securing the cooperation of the Russian and US governments and ended with an aboriginal quota for bowhead whales for the Russian Federation from the International Whaling Commission. Typykhkak assisted his younger son's crew to harvest a bowhead whale in 1998, after a more than a 25-year hiatus of the tradition. In 1997, Typykhkak helped form and was elected the president of the Union of Marine Mammal Hunters, and was able to employ his skills and knowledge protecting traditional subsistence. Under his leadership, the Union of Marine Mammal Hunters became well-known in Russia and internationally as a native organization interested in protecting the traditional lifestyle of the native people while being actively involved in the management of ma- rine resources. Typykhkak represented the organization at the 2000 meeting of the International Whaling Commis- sion in Australia. He is greatly mourned by his Russian colleagues. In his obituary in the Russian press it was written that 'Peter was one of the most reliable protectors of the traditional marine mammal hunt and the spirit of the Eskimo people, and he prepared an entire generation of talented hunters, sailors, and Arctic naturalists. He was especially known for his wisdom, his love of people, his drive, his integrity, and his honesty.' Typykhkak was also well liked by Alaskans. He often visited Alaska representing the native people of Chukotka. Early in 2000, the US National Park Service and employ- ees of the North Slope Borough arranged for a Fairbanks ophthalmologist, Dr Zamber, to volunteer his time to operate on Typykhkak's cataracts, which had made him almost blind. People from all over Alaska contributed money to the operation, which was a success. Sponsored by Roman Abramovich, Typykhkak returned for medical attention to Anchorage in October 2000. Unfortunately, he was diagnosed with terminal stomach cancer and returned to his native village in November. He is survived by three sons and two daughters. Vladimir Etylin John Tichotsky work_5gjo6qhoejdxlcutcyd7nerwo4 ---- In This Issue The five articles published in this issue of the Law and History Review examine fundamental questions of legal history and historiography. In our first article, Ian Holloway addresses the resurgence in Australia, including among the courts, of fascination with Australian and colonial legal histo- ry. But he notes an important absence in this resurgence: with respect to public law, there has been little, if any, interest in how English traditions of judicial control of the executive took root in Australia, and what impact this may have had on the development of the present-day system of public law. Holloway's article responds to that gap in scholarship by exploring and analyzing the earliest cases of record, in which the Supreme Court of New South Wales began to enforce the rule of law against public authorities. As Holloway points out, access to these cases has been made possible for the first time by Bruce Kercher's internet-based project to publish annotated copies of the earliest records of the Supreme Courts of New South Wales and Van Diemen's Land (Tasmania), described by Kercher in "Recovering and Reporting Australia's Early Colonial Case Law: The Macquarie Project," Law and History Review 18.3 (Fall 2000): 659-65. Readers who access Holloway's article in our electronic edition will be able to view the cases he discusses through live links to the Macquarie project database. Our second article, by Ernest Metzger, has important implications both for the contemporary study of Roman law and for understanding how Roman law has, in the past, been studied. As such it is simultaneously an exercise in writing legal history and an examination of the production of legal history, particularly in the research of the nineteenth century's Ger- man Historical School. As Metzger notes, Roman law has been admired for a long time. But its admirers, in their enthusiasm, have sometimes bor- rowed ideas from their own time and attributed them to the Romans, thereby filling some gap or fixing some anomaly. Roman private law is a well- known victim of this. Roman civil procedure has been a victim as well, and the way Roman judges are treated in the older literature provides an ex- ample. For a long time it has been accepted, and rightly so, that the deci- sion of a Roman judge did not make law. But the related, empirical ques- tion, whether Roman judges ever relied on the decisions of other judges, has been largely ignored. The common opinion, which today correctly re- jects "case law," passes over "precedent" without comment. It does so because for many years an anachronistic view of the Roman judge was in fashion. According to this, a Roman judge's decision expressed the peo- Cambridge Core terms of use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0738248000015273 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:28, subject to the https://www.cambridge.org/core/terms https://doi.org/10.1017/S0738248000015273 https://www.cambridge.org/core pie's sense of right about a specific set of facts. Thus, a decision is simply a piece of information for an expert to examine; it has no value to another judge. With the passing of this view, however, the common opinion could accept the existence of precedent in Roman law. In our third article, by Bruce Kimball, we move even more explicitly to the question of how central tropes of legal history—in this case U.S. legal history—emerge. Since his death in 1906, Christopher Columbus Langdell—arguably the most influential figure in the history of legal edu- cation in the United States—has been the subject of ceaseless examination by members of the legal profession and academe. Despite the enormous influence of his reforms, this discussion has generally presented a depreci- ating, even disparaging, view of Langdell. Moreover, this has prevailed even though the majority of Langdell's writings have never been studied. These two paradoxes constitute the "Langdell Problem" in the historiography of the last century. Kimball's article addresses and explains the Langdell prob- lem by demonstrating that commentary on Langdell throughout the twen- tieth century has drawn primarily from published studies without consider- ing whether these are validated by evidence from original sources. The result has been the accumulation of an imposing, deeply sedimented, mound of scholarship obscuring the neglect of original sources. This sedimentation has grown because the received view of Langdell has, in a variety of ways over the past century, served the purposes of legal scholars. By historicizing the historiography, Kimball discloses the irony that the law professor who taught his profession to scrutinize every general propo- sition in light of the original sources about specific cases has had his story told and his legacy shaped by many who flouted his most fundamental prin- ciple. He concludes that the received view of Langdell rests on a relatively insubstantial evidentiary base and that a fuller, more complex understand- ing of Langdell and his legacy to modern legal education is needed. Our fourth article continues this issue's historiographical theme and is the subject of its forum. Alejandro de la Fuente reviews literature focusing on slavery and the law in Spanish America and analyzes the use made by slaves of traditional Spanish law and legal customs to claim rights before author- ities and the courts. Using Cuba as a case study, de la Fuente argues that slaves who became familiar with the dominant culture—typically through their participation in urban market relations—learned that under Spanish law they had some rights, including the right to appeal to authorities. Even in the nineteenth century, when Cuba became a prosperous slave-based plan- tation society and a leading producer of sugar, urban slaves continued to invoke these laws to ameliorate their position. De la Fuente notes that the importance of this legal order was recognized by Frank Tannenbaum in his influential 1946 essay Slave and Citizen. But unlike Tannenbaum, who as- sumed that positive laws endowed slaves with a "moral" personality, de la Cambridge Core terms of use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0738248000015273 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:28, subject to the https://www.cambridge.org/core/terms https://doi.org/10.1017/S0738248000015273 https://www.cambridge.org/core Fuente argues that it was the slaves themselves who gave concrete social meaning to the abstract rights regulated in the positive laws by making claims and pressing for benefits. Tannebaum, however, was correct to note the persistent relevance of the traditional statutes of Castile in the colonies, for as late as the nineteenth century Cuban courts continued to invoke the thirteenth-century code Siete Partidas in their verdicts concerning slaves. De la Fuente's position is debated by Maria Elena Diaz and Christopher Schmidt-Nowara. The forum concludes with de la Fuente's response. This issue of the Law and History Review is unique in that, in addition to the forum just described, it also presents the first part of a two-part fo- rum that will conclude in our next, Fall 2004, issue. Here we present the opening of Michael Lobban's treatment of the reform of the English Court of Chancery. By the early nineteenth century, Lobban tells us, the Court of Chancery was perceived to be in crisis: slow and costly, it bore all the hallmarks of a corrupt ancien regime institution. His two-part article ex- amines the process of reforming the court in the sixty years before the Judicature Acts of 1873-75. Debates over reform before 1852 were dom- inated by two issues. The first (explored here) was the question of wheth- er the court's allotment of judicial personnel was adequate to cope with the demands of litigation. Although this question attracted the most political attention—notably in Lord Eldon's era—it was not satisfactorily resolved, for politicians remained uncertain about the nature of Chancery's arrears and cautious about appointing new judges or altering the functions of the Chancellor. The second issue (explored in Part II) was the technical ques- tion of how to simplify Chancery's complex procedures and reform its inefficient offices. The legal profession was the driving force behind ma- jor reforms in these areas, which were achieved by 1852. With many of the old faults of the Chancery addressed, after the mid-nineteenth century, reformers turned their minds toward a larger question of principle—the fusion of the courts of law and equity into a single judicature. Comments on Lobban's article, with his response, will appear in the next issue. As always, the issue concludes with a comprehensive selection of book reviews. As always, too, we encourage readers to explore and contribute to the American Society for Legal History's electronic discussion list, H-Law. Readers are also encouraged to investigate the LHR on the web, at www.historycooperative.org, where they may read and search every issue published since January 1999 (Volume 17, No.l), including this one. In ad- dition, the LHR's own web site, at www.press.uillinois.edu/journals/lhr.html, enables readers to browse the contents of forthcoming issues, including ab- stracts and, in almost all cases, full-text PDF "pre-prints" of articles. Christopher Tomlins American Bar Foundation Cambridge Core terms of use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0738248000015273 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:28, subject to the https://www.cambridge.org/core/terms https://doi.org/10.1017/S0738248000015273 https://www.cambridge.org/core work_5ib2dsz6gzgpdl4lwbfds7ivey ---- The Doctrine of Discovery: The International Law of Colonialism UCLA The Indigenous Peoples’ Journal of Law, Culture & Resistance Title The Doctrine of Discovery: The International Law of Colonialism Permalink https://escholarship.org/uc/item/3cj6w4mj Journal The Indigenous Peoples’ Journal of Law, Culture & Resistance, 5(1) Author Miller, Robert J. Publication Date 2019 Peer reviewed eScholarship.org Powered by the California Digital Library University of California https://escholarship.org/uc/item/3cj6w4mj https://escholarship.org http://www.cdlib.org/ 35 © 2019 Robert J. Miller. All rights reserved. THE DOCTRINE OF DISCOVERY: The International Law of Colonialism Robert J. Miller* Indigenous Peoples around the world have been seriously and negatively impacted by the international law of colonialism, which is known today as the Doctrine of Discovery.1 The Doctrine was developed primarily in the fifteenth century by Spain, Portugal, England, and the Church.2 The Doctrine is not just an interesting relic of world history but instead remains an applicable principle in many countries and also continues to limit the human, sovereign, commercial, and property rights of Indigenous Peoples and their governments. The Doctrine was used by European nations to justify their desires to acquire riches and empires around the world. The European powers primarily justified these acqui- sitions and their ambitions by ethnocentric allegations of cultural, racial, governmental, and religious superiority over the rest of the world. Indigenous Nations and Peoples, and everyone for that matter, need to understand how this international law of colonialism was de- veloped, how it was justified, how it was used to subjugate Indigenous Peoples, how it was used to steal Indigenous lands, assets, and rights, and how it has impacted Indigenous Peoples from the onset of colonization to the present day. * Professor, Sandra Day O’Connor College of Law, Arizona State University; Facul- ty Director, Rosette LLP American Indian Economic Development Program; Navajo Nation Council of Economic Advisors; Justice, Court of Appeals, Grand Ronde Tribe; Citizen, Eastern Shawnee Tribe. 1 See Robert J. Miller, The International Law of Colonialism: A Comparative Anal- ysis, 15 Lewis & Clark L. Rev. 847 (2011); Robert J. Miller & Micheline D’Angelis, Brazil, Indigenous Peoples, and the International Law of Discovery, 37 Brook. J. Int’l L. 1 (2011); Robert J. Miller, Lisa LeSage & Sebastián López Escarcena, The Inter- national Law of Discovery, Indigenous Peoples, and Chile, 89 Neb. L. Rev. 819 (2011); Robert J. Miller, Jacinta Ruru, Larissa Behrendt & Tracey Lindberg, Discovering Indigenous Lands: The Doctrine of Discovery in the English Colonies (2010). 2 Robert J. Miller, Native America, Discovered and Conquered: Thomas Jeffer- son, Lewis & Clark, and Manifest Destiny 9–33 (2006). 36 2019:35I P J L C R Similarly, one must understand another principle of international law to fully appreciate the modern-day importance of the fifteenth centu- ry Doctrine of Discovery. According to the principle of “intertemporal” law, modern-day territorial boundaries and land titles “are to be judged by the law in force at the time the title was first asserted and not by the law of today.”3 Consequently, how European countries and their colonies divided up the lands and assets of Indigenous Peoples and Nations in the distant past still determines national boundaries today and thus is highly relevant to Indigenous Peoples. The international law that regulated nearly six hundred years of European colonization can be traced in church law and world history to at least the Crusades to reclaim the Holy Lands in 1096–1271.4 The modern day version of this legal principle started to emerge in the 1430s due to Spanish and Portuguese claims to control and colonize the Canary Islands.5 In 1436, Portugal finally convinced Pope Eugenius IV to issue a papal bull granting Portugal exclusive control of the Islands to civilize and convert the Canary Islanders to the “one true religion” and “for the salvation of the souls of the pagans of the islands.”6 As Portugal expand- ed its explorations and claims down the west coast of Africa, it convinced Pope Nicholas to issue another bull. On January 8, 1455, the Pope grant- ed Portugal the power: to invade, search out, capture, vanquish, and subdue all Saracens [Muslims] and pagans whatsoever, and other enemies of Christ wheresoever placed, and the kingdoms, dukedoms, principalities, dominions, possessions, and all movable and immovable goods what- soever held and possessed by them and to reduce their persons to perpetual slavery, and to apply and appropriate to himself and his successors the kingdoms, dukedoms, counties, principalities, domin- ions, possessions, and goods, and to convert them to his . . . use and profit . . . [and to] possess, these islands, lands, harbors, and seas, and they do of right belong and pertain to the said King Alfonso and his successors . . . .”7 Not surprisingly, in 1493 Spain also sought papal approval for the discoveries Columbus made in the New World. According to the develop- ing international law, Pope Alexander VI issued three bulls and ordered that the lands Columbus discovered, which were “not hitherto discovered 3 John Dugard, International Law: A South African Perspective 113–14 (2d ed. 2000). 4 See, e.g., Robert A. Williams, Jr., The American Indian in Western Legal Thought: The Discourses of Conquest 14 (1990); The Expansion of Europe: The First Phase (James Muldoon ed., 1977); Carl Erdmann, The Origin of the Idea of Crusade (Marshall W. Baldwin & Walter Goffart trans., Princeton Univ. Press 1977) (1935). 5 Miller, Native America, supra note 2, at 13–14. 6 Williams, supra note 4, at 71. 7 European Treaties Bearing on the History of the United States and its De- pendencies to 1648 23 (Frances Gardiner Davenport ed., 1917). 37Doctrine of Discovery by others,” belonged to Spain.8 The Pope further granted Spain lands it would discover in the future if they were not “in the actual posses- sion of any Christian king.”9 The Pope then drew a line of demarcation from the North to the South Poles, 300 miles west of the Azores Islands, granting Spain title to the lands “discovered and to be discovered” west of that line, and granting Portugal the same rights east of the line.10 In 1494, Spain and Portugal signed the treaty of Tordesillas moving the line further west to give Portugal part of the New World, today’s Brazil.11 In 1529, in the Treaty of Zaragosa, the countries extended the line around the globe and divided up the Pacific Ocean and its islands and lands.12 Thereafter, Spain and Portugal applied the Doctrine of Discovery in Africa, Asia, and the Americas.13 Jealous to acquire empires and riches themselves, England, Holland, and France also used this international law to claim rights in North America and elsewhere.14 The colonial- settler so- cieties that resulted from European colonization of much of the world, including the United States, continue to apply the Doctrine of Discovery against Indigenous Nations today.15 A correct understanding of the Doctrine of Discovery and its world- wide application can be gained by studying the world’s leading court 8 Id. at 9–13, 23, 53–56. 9 Id. 10 The Spanish Tradition in America 38 (Charles Gibson ed., 1968); Church and State Through the Centuries 156 (Sidney Z. Ehler & John B. Morrall trans. & eds., 1967); Samuel Eliot Morison, Admiral of the Ocean Sea: A Life of Christopher Columbus 368–73 (1942). 11 Foundations of Colonial America: A Documentary History 1684 (W. Keith Ka- venagh ed., 1973); The Spanish Tradition, supra note 10, at 42–51. 12 Samuel Eliot Morison, The European Discovery of America: The Southern Voyages A.D. 1492–1616 476–77, 490–91, 498 (1974). 13 Miller, Native America, supra note 2, at 13–17; Robert J. Miller, The International Law of Discovery: Acts of Possession on the Northwest Coast of North America, in Arctic Ambitions: Captain Cook and the Northwest Passage (James K. Barnett & David L. Nicandri eds., 2015); Manuel Servin, Religious Aspects of Symbolic Acts of Sovereignty, 13 The Americas 255 (Jan. 1957); Manuel Servin, The Act of Sovereignty in the Age of Discovery (Jan. 1959) (unpublished Ph.D. dissertation, University of Southern California). 14 Miller, Ruru, Behrendt & Lindberg, supra note 1; Miller, Native America, su- pra note 2, at 17–21, 25–33; Miller, The International Law of Discovery, supra note 13; Servin, The Act of Sovereignty, supra note 13. 15 See supra notes 13–14. Scandinavian countries have also applied aspects of the Doctrine of Discovery against the Sami people. See Landowners and right-holders in Manndalen, et al v. The Norwegian State, Serial No. 5B/2001, No. 340/1999 (2001) (Supreme Court of Norway); Riast/Hylling Sami v. Kjell Bendixvold et al, Frostat- ing Lagmannsrett LF-1995-00034 A, Supreme Court HR-1997-00061 A, No. 96/1996 (1997) (Norway); North Frostviken Sami Village v. State, S.Ct. Decision No. DT 2, Case No. 324/76 (1981) (Supreme Court of Sweden); Veli-Pekka Lehtola, The Sami Siida and the Nordic States From the Middle Ages to the Beginning of the 1900s, in Conflict and Cooperation in the North 183–94 (Kristina Karppi & Johan Eriksson eds., 2000). European countries also used aspects of the Doctrine to claim and divide Africa in 1885. See M.E. Chamberlain, The Scramble for Africa 28–83 (2d ed. 1999); S.E. Crowe, The Berlin West African Conference 1884–1885 3, 95–191 (1942). 38 2019:35I P J L C R case on Discovery: the United States Supreme Court case of Johnson v. McIntosh.16 The Johnson case has heavily influenced how colonial-settler societies have defined Discovery and their “rights,” and how they have diminished the rights of Indigenous Nations and Peoples. Johnson has been relied on by many countries to decide issues regarding colonization and the rights of Indigenous Nations. The case has been cited scores of times by courts in Australia,17 Canada,18 New Zealand,19 and the United States.20 The English Privy Council cited Johnson three times in cases regarding colonization in Africa and Canada.21 In Johnson v. McIntosh, non-Indians sued each other over who was the legal owner of lands formerly owned by Indian Nations in what is now the state of Illinois. The plaintiffs claimed their rights through corpora- tions that had allegedly bought the lands in question from Indians in 1773 and 1775.22 In contrast, the defendant, McIntosh, had purchased his land in 1818 from the United States, which had acquired it via treaties with the Piankeshaw and Illinois Indian Nations.23 The U.S. Supreme Court decided that McIntosh was the owner because Indian Nations were not considered to be the full owners of their lands after Euro-Americans ar- rived and claimed a property interest in Indian lands.24 Thus, the Court held that, under the Doctrine, Indian Nations could only sell their lands to the Euro-American government that claimed the Discovery power over them, and therefore that the purported sales to the corporations were invalid.25 The U.S. Supreme Court repeatedly stated in Johnson that the Doctrine and the loss of rights suffered by Indian Nations were based on the justifications of Christianity and civilization. The Court stated for example: “the character and religion of its inhabitants afforded an 16 21 U.S. (8 Wheat.) 543 (1823). For a brief description of the case see Miller, Na- tive America, supra note 2, at 50–56. 17 Ten or more Australian cases have cited Johnson. See, e.g., Western Australia v Ward (2000) 99 FCR 316, 170 ALR 159; Mabo v Queensland [No. 2] (1992) 175 CLR 1, 107 ALR 1. 18 At least forty-four Canadian cases have cited Johnson. See, e.g., R. v. Sparrow, [1990] 70 D.L.R. (4th) 385, 1 S.C.R. 1075 (Supreme Court of Canada); Kwicksutaineuk/Ah- Kwa-Mish First Nation v. British Columbia, [2011] 55 C.E.L.R. (3d) 165, 15 B.C.L.R. (5th) 322 (British Columbia Supreme Court). 19 See, e.g., Attorney-General v. Ngati Apa [2003] 3 NZLR 643; Wi Parata v. Bishop of Wellington (1877) 3 NZ Jur (NS) 72 (SC); R. v. Symonds (1847) NZPCC 387. 20 Johnson has been cited hundreds of times by federal and state courts in the United States. See, e.g., Attorney’s Process v. Sac & Fox Tribe, 609 F.3d 927 (8th Cir. 2010). See also City of Sherrill v. Oneida Indian Nation of N.Y., 544 U.S. 197, 203 n.1 (2005). 21 Amodu Tijani v. Secretary, Southern Nigeria, [1921] 2 A.C. 399 (Privy Council); In re Southern Rhodesia, [1919] A.C. 211 (Privy Council); Canada v. Ontario, [1910] A.C. 637 (Privy Council); St. Catherine’s Milling and Lumber Co. v. The Queen, (1889) L.R. 14 App. Cas. 46 (Privy Council). 22 Johnson v. M’Intosh, 21 U.S. (8 Wheat.) 543, 550–51, 555, 571 (1823). 23 Id. at 560; Miller, Native America, supra note 2, at 51. 24 Johnson, 21 U.S. at 604–05. 25 Id. at 574, 587. 39Doctrine of Discovery apology for considering them as a people over whom the superior genius of Europe might claim an ascendency.  .  .  .  [A]mple compensation [was made] . . . by bestowing on them civilization and Christianity, in exchange for unlimited independence.”26 The Court also claimed “some excuse, if not justification, [for the loss of Indigenous rights] in the character and habits of the people whose rights have been wrested from them.”27 The international law principle that Indigenous Peoples and Na- tions around the world did not and do not own the full title to their lands is still the law in most countries today.28 An effective method to understand and analyze the Doctrine, and to compare how Euro-Americans applied it throughout the world, is to delineate the constituent elements that make up Discovery. These ele- ments are easy to discern from a close reading of Johnson v. McIntosh. The elements are clearly reflected in the laws, treaties, court cases, pol- icies, and histories of almost all European settler societies around the world. I define the ten elements of Discovery in the following manner.29 1. Christianity. Religion was a very significant aspect of Discovery. Start- ing with the Crusades and then the papal bulls of the 1400s, Christians claimed that Indigenous Nations and Peoples did not have the same rights to land, sovereignty, self-determination, and human rights as did Christians. Furthermore, Europeans claimed a right and duty to convert non-Christians. 2. Civilization. European cultures and civilizations were presumed to be superior to Indigenous Peoples and their civilizations. European countries claimed that the Christian God had directed them to civilize Indigenous Peoples and to exercise paternal and guardian powers over them. 3. First discovery. The first European country that discovered lands un- known to other Europeans claimed property, commercial, and sovereign rights over the lands and the Indigenous Nations and Peoples. Conse- quently, the Doctrine created a race among European powers to discover and claim the non-European world. 4. Actual occupancy and possession. To turn a first discovery into a full title of ownership that would be recognized by other European countries, England developed in the 1570s the element that a European country had to actually occupy and possess the lands it claimed via a first dis- covery. Occupancy was usually proved by building forts or settlements. The physical occupancy and possession had to be accomplished within a reasonable amount of time after making a first discovery.30 26 Id. at 573 (emphasis added). 27 Id. at 589 (emphasis added). 28 See, e.g., Miller, The International Law of Colonialism, supra note 1; Miller & D’An- gelis, supra note 1; Miller, LeSage & Escarcena, supra note 1; Miller, Ruru, Beh- rendt & Lindberg, supra note 1. 29 Miller, Native America, supra note 2, at 3–5. 30 Island of Palmas Case (Neth. v. U.S.), 2 R.I.A.A. 829, 845 (Perm. Ct. Arb. 1928) 40 2019:35I P J L C R 5. Preemption. Euro-American countries that claimed the rights of first discovery also claimed the power of preemption, that is, an exclusive right to buy the lands of Indigenous Nations and Peoples. This is a valu- able property right similar to the modern-day real estate principle called a right of first refusal, which is the right to be the first person allowed to purchase another’s land when they choose to sell. Under Discovery, the Euro-American government that held the preemption right could pre- vent, or preempt, any other Euro-American government or individual from buying land from Native Nations. Most colonial-settler societies still claim this property right over Indigenous Nations and Peoples today. 6. Indian/Native title. After a first discovery, Euro-American legal systems claimed that Indigenous Nations automatically lost the full own- ership of their lands and only retained what is called the “Indian title” or “native title,” a property right to occupy and use the lands. These rights could last forever if Indigenous Nations never consented to sell to the Euro-American country that claimed first discovery and preemption. But if Indigenous Nations did choose to sell, they were to sell only to the Euro-American government that held the preemption right. 7. Limited Indigenous sovereign and commercial rights. Euro-Ameri- cans claimed that Indigenous Nations and Peoples lost other aspects of their sovereignty and their rights to engage in international trade and treatymaking after a first discovery. Euro-Americans claimed that Indig- enous Nations could only interact politically and commercially with the Euro-American government that had discovered them. 8. Contiguity. Euro-Americans claimed a significant amount of land contiguous to and surrounding their actual discoveries and colonial settlements. For example, when European countries had settlements somewhat close together, each country claimed rights over the unoccu- pied lands between their settlements to a point half way between their settlements.31 Contiguity provided, for example, that the discovery of the mouth of a river created a claim over all the lands drained by that river.32 (holding that “symbolical . . . possession . . . completed eventually by an actual and du- rable taking of possession within a reasonable time” created a complete title); Miller, Native America, supra note 2, at 72–76, 133–44 (President Jefferson and others were concerned that the United States quickly settle the Pacific Northwest so that actual possession would solidify the United States’ claim to title based on first discovery); Mark A. Smith, Jr., Sovereignty Over Unoccupied Territories—The Western Sahara De- cision, 9 Case W. Res. J. Int’l L. 135, 135 n.2 (1977). 31 Miller, Native America, supra note 2, at 69–70 (President Thomas Jefferson dis- cussed the idea of contiguity as part of European Discovery claims), 138 (House of Representatives 1821 report discussed principles of contiguity as establishing Europe- an Discovery claims). 32 Id. at 67, 70 (Secretary of State Jefferson in 1792 and President Jefferson in 1804), 138 (House of Representatives 1821 report), 147 (Congressman speech 1838). Com- pare the boundaries of the Louisiana Territory and the Oregon Country. U.S. Terri- torial Map 1810, http://xroads.virginia.edu/~MAP/TERRITORY/1810map.html (last visited Nov. 15, 2018). 41Doctrine of Discovery 9. Terra nullius. This Latin phrase means a land that is vacant or empty. Under this element of the Doctrine, if lands were not occupied by any person or nation, or even if they were occupied but they were not being used in a manner that Euro-American legal systems approved, then the lands were considered empty, vacant, and available for Discovery claims.33 Euro-Americans often considered lands that were actually owned, occu- pied, and being used by Indigenous Nations to be terra nullius. 10. Conquest. Euro-Americans claimed they could acquire through mil- itary victories the absolute title and ownership of the lands of Indigenous Nations. Conquest was also used as a term of art to describe the property and sovereign rights Euro-Americans claimed to acquire automatically over Indigenous Nations and Peoples just by making a first discovery. These ten elements are plainly evident in the histories and modern-day laws and policies of all settler societies. These elements were used, and are still being used, to justify limitations on the sovereign- ty, property, and human rights of Indigenous Nations. What can Indigenous Nations and Peoples and their supporters do today to oppose the existence of the Doctrine of Discovery and to repeal its pernicious effects? Several suggestions have been put forward by In- digenous Nations, scholars, and activists.34 First, many people have called on the international community, and the United Nations in particular, to study and truly understand the Doctrine and to begin a process of repudiating and reversing this six hundred-year-old ethnocentric, racist, and feudal legal doctrine. Second, Indigenous scholars and advocates have suggested that all governments review their laws, regulations, and policies that impact Indigenous Peoples and repeal those that are based on the prejudices and fallacies of the Doctrine.35 Furthermore, these governments should undertake such reviews in full consultation with Indigenous Nations and Peoples.36 33 Miller, Native America, supra note 2, at 21–22, 24, 26–28, 56. See also Johnson, 21 U.S. at 595–97 (discussing the Crown’s ownership of, and right to grant titles to, the vacant lands in America); Martin v. Waddell, 41 U.S. 367, 409 (1842) (“[T]he territory [] occupied was disposed of by the governments of Europe at their pleasure, as if it had been found without inhabitants.”); United States v. Rogers, 45 U.S. 567, 572 (1846) (“the whole continent was divided and [parceled out], and granted by the govern- ments of Europe as if it had been vacant and unoccupied land”). 34 See, e.g., The Doctrine of Discovery: The International Law of Colonialism, Con- ference Room Paper, U.N. Permanent Forum on Indigenous Issues, Eleventh Session (May 7–18, 2012) (hard copy on file with author); ‘Doctrine of Discovery’, Used for Centuries to Justify Seizure of Indigenous Land, Subjugate Peoples, Must Be Repudiat- ed by United Nations, Permanent Forum Told, U.N. Permanent Forum on Indigenous Issues, Eleventh Session (May 8, 2012), available at https://www.un.org/press/en/2012/ hr5088.doc.htm. 35 See, e.g., Miller, Native America, supra note 2, at 175–78. 36 Robert J. Miller, Consultation or Consent; The United States’ Duty to Confer with American Indian Governments, 91 N.D. L. Rev. 37 (2015); Colette Routel & Jeffrey 42 2019:35I P J L C R Third, Indigenous Nations and Peoples have called on all gov- ernments to educate their citizens, incorporate at all levels of formal education the true and complete history of their countries, and include the impact and application of colonization and the Doctrine of Discovery on their Indigenous citizens.37 Finally, Indigenous Nations and Peoples have been working with many churches to join them in repudiating the Doctrine of Discovery. Many churches and church organizations have already done so; for ex- ample, the Episcopal Church in 2009, the Anglican Church of Canada in 2010, the World Council of Churches Executive Committee in 2012, the Unitarian Universalists, individual Quaker congregations, the Unit- ed Church of Christ, the United Methodist Church, the Community of Christ, and in June 2016 the General Assembly of the Presbyterian Church USA. How much longer can modern-day societies and churches continue to tolerate the kind of ignorance, and non-Christian principles of death, domination, prejudice, inequity, and violation of sovereign and human rights that the Doctrine of Discovery represents? Clearly, all settler so- cieties need to learn how to repudiate and repeal this Doctrine because it is based on ethnocentric, racist, religious, and feudal ideas that have no place in the modern-day world. Holth, Toward Genuine Tribal Consultation in the 21st Century, 46 U. Mich. J.L. Re- form 417 (2013). 37 See Miller, Native America, supra note 2, at 175–78. https://www.pcusa.org/ https://www.pcusa.org/ work_5lh2r6b3f5gorck3llr3wf7afy ---- wp-p1m-38.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-38.ebi.ac.uk no 218194697 Params is empty 218194697 exception Params is empty 2021/04/06-02:09:19 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. Message ID: 218194697 (wp-p1m-38.ebi.ac.uk) Time: 2021/04/06 02:09:19 If you need further help, please send an email to PMC. Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_5mlsctddbbg4tmsaeakv2lhham ---- In This Issue As 1999 winds to a close, and with it (give or take a year) both the twen- tieth century and the second millennium, it is perhaps appropriate that in this issue of the Law and History Review we pay our respects to the roots of our discipline, with articles and essays that explore issues of fundamental importance in the broad continuum of Anglo-American legal history, reach- ing from the nineteenth century back to the ninth. Our first article, by Howard Schweber, reexamines the conception of science and scientific method to which nineteenth-century American legal educators had resort in developing their own idea of law as a science. Far from modern ideas of scientific method, Schweber argues, the conception of science that was appropriated by antebellum legal educators was that dominant in contemporaneous public discussion of natural science, as ev- idenced in lyceums, surveys, and journals. Public scientific discourse em- ployed a language grounded in the same religious commitments and the same normative conception of nature that drove the ideology of laissez- faire. Legal scientific writers from the 1820s onward used that discourse to replace the historical jurisprudence of Hale and Blackstone and the moral legal science of Kent and Story, treating "law" as a species of natural ob- ject. Described here as "Protestant Baconianism," the approach was char- acterized by commitments to four elements: natural theology; a constrained version of Baconian inductivism; a belief in grand synthesis and proof by analogy; and claims of moral improvement. In the natural sciences, respect for the Protestant Baconian conception of science did not survive the Civ- il War. In law, Schweber argues, the story is a little different. Attempting to continue to invoke the powerful idea of "legal science," Christopher Co- lumbus Langdell assembled the remnants of the Protestant Baconian ap- proach into his case method. In the 1870s, that is, crucial elements of the discredited antebellum approach to natural science were given new life in Langdell's "new" model of legal science. These surviving elements of an earlier natural scientific tradition have continued to influence legal educa- tion to this day. In our second article, Martin Wiener undertakes a close inspection of English trial and post-trial proceedings in cases of murder during the nine- teenth century, resulting in an elucidation of several developments of con- siderable importance to the history of English criminal law. Wiener finds significant tension between judges increasingly determined to repress in- Core terms of use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0738248000011615 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:22, subject to the Cambridge https://www.cambridge.org/core/terms https://doi.org/10.1017/S0738248000011615 https://www.cambridge.org/core terpersonal violence and juries increasingly receptive to defense arguments for mitigation. He further finds that, in conjunction with a wider contem- poraneous reconception of notions of personhood and responsibility in the general culture, this tension had an impact upon the law of criminal respon- sibility. Judge-jury conflict both exhibited and contributed to movement in the effective meanings of legal terms such as provocation, intention, and insanity. Judges propagated, and juries gradually accepted, the idea of the "ordinary reasonable man," who was expected not to be easily provoked, nor to become dangerously intoxicated. On the other hand, juries (and the home office) were increasingly receptive to insanity defenses scorned by judges. By 1900, Wiener shows, the scope of provocation and lack of in- tention defenses had narrowed, while that of insanity had broadened. Our third article, by Norma Landau, maintains our focus on English court proceedings while removing us from the nineteenth century to the eigh- teenth, and from murder trials to the more prosaic stuff of Quarter Sessions. Based on research on the general releases in the papers of Middlesex's Quarter Sessions, Landau argues that the overwhelming majority of eigh- teenth-century indictments at Quarter Sessions for such offenses as assault, riot, and other nonfelonious offenses against the person were actually brought by prosecutors using indictment as a means to extract compensa- tion in some form from defendants. Releases, she tells us, have not been analyzed in discussions of early modern English courts. Research on the Middlesex releases shows that, for a very large proportion of indictments found at Quarter Sessions, defendants satisfied their prosecutors, who then signed releases that rendered them unable to prosecute the indicted defen- dants. The court of Quarter Sessions facilitated such settlements and even adopted procedures designed to encourage defendants to satisfy their pros- ecutors. This finding raises important questions about the assumptions defining categories basic to current discussion of early modern crime and the courts. Quarter Sessions has been categorized as a "criminal" court, indictments as "criminal procedures," and defendants to these indictments as putative "criminals." But in these indictments both the court's procedures and the protagonists' behavior actually bear considerable resemblance to proceedings on civil suits. Our fourth article, by Mike Macnair, also offers a remarkably interest- ing reassessment of an institution fundamental to received notions of the meaning of legal proceedings, and provides us with our "forum" for this issue. In his article, Macnair lays out a new approach to the venerable question of the origins of trial by jury. The traditional approach, Macnair tells us, investigated the character of the jury as a system of lay judgment. In contrast the "Brunner thesis," dominant until recently, focused on early juries as forms of royal inquiry. In recent years scholars have favored ap- Core terms of use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0738248000011615 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:22, subject to the Cambridge https://www.cambridge.org/core/terms https://doi.org/10.1017/S0738248000011615 https://www.cambridge.org/core preaching the jury as a survival of early medieval practices in which col- lective testimony and judgment were indistinct. Macnair departs from all three of these tendencies, concentrating on the requirement that the jury come "de visneto," that is, from the locality. The use of groups of "vicini" to establish local reputation to prove "local" facts, he argues, had anteced- ents in late Roman and early medieval normative sources; the uses of spe- cial panels of locals in Anglo-Norman England are most consistent with the ideas of these sources. Local reputation was probably an acceptable form of evidence at least in these "local" matters in eleventh-century can- non law. The extension of the use of panels of locals under Henry II may therefore represent a compromise solution to conflicts of jurisdiction and procedure between the royal and church courts. This would explain the tendency to see jurors as a type of witnesses that persisted in later medi- eval common law doctrine; and this, in turn, in its own politico-legal con- text, may help explain the persistence of jury trial in the common law. Charles Donahue and Patrick Wormald comment on the significance of Macnair's argument and conclusions. The forum concludes with Macnair's response. As usual the issue is rounded off by our book reviews and by another in our continuing series of electronic resource pages. In this issue's page, Terence Halliday of the National Institute for Social Science Information (NISSI) describes the potential of the Internet as a site for the dynamic organization of knowledge. As always, readers of the Law and History Review are encouraged to explore and contribute to the American Society for Legal History's electronic discussion list, H-Law, which offers a con- venient forum for, among other matters, discussion of the scholarship on display in the Review. Readers will also find the address of the Review's own web page displayed on the issue's contents page. Christopher Tomlins American Bar Foundation Core terms of use, available at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S0738248000011615 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:22, subject to the Cambridge https://www.cambridge.org/core/terms https://doi.org/10.1017/S0738248000011615 https://www.cambridge.org/core work_5mklkx74kfbjnmlnuv476crjke ---- INVITED DISCOURSES at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S1539299600004950 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:25, subject to the Cambridge Core terms of use, available https://www.cambridge.org/core/terms https://doi.org/10.1017/S1539299600004950 https://www.cambridge.org/core ASTRONOMY IN ANCIENT GREECE Michael Hoskin University of Cambridge Abstract: Science has spread from western Europe where it developed into recognisably-modern form in the seventeenth century, stimulated by Copernicus's claim that the Earth is a planet. Copernicus however was an astronomer in the Greek tradition, whose task was to reproduce the planetary paths by geometrical constructions using uniform circular motions. Eudoxus's attempt to do this with nests of concentric spheres had been superseded by the use of the more flexible techniques necessary to meet the observational standards of the Hellenistic era. Ptolemy's Almagest synthesised the Greek achievement but its shortcomings led Copernicus to make the Earth a planet. Our purpose this evening is to travel back in time for two thousand years and more, and to try to enter the minds of those men of the period who worked to understand the heavens and to explain and predict the motions of the stars and planets, and who communicated their conclusions to their fellow-men in the Greek language. And I shall outline reasons why their achievement was of decisive importance, not only for the history of astronomy but for the development of modern science as we know it. First, some general comments by way of orientation. Those like myself who spent most of their school years studying Latin and Greek were encouraged to think that Greek culture came to an end with the death of Alexander the Great in 323 BC and that of Aristotle the follow- ing year. But by then Greek astronomy was still in its infancy, and Claudius Ptolemy, the dominating figure in our story, died around 170 AD, some five centuries later. That is to say, major astronomers wrote in Greek for at least five hundred years after the decline of Athenian culture, and for our purpose the years after Christ are as important as those before. Nor, for the most part, was astronomy written on the main land of what is now Greece. Of where the great astronomers lived and worked we know extraordinarily little, but the places mentioned are mostly in 3 Richard M. West (ed.j. Highlights of Astronomy, Vol. 6,3-14. Copyright © 1983 by the IAU. at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S1539299600004950 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:25, subject to the Cambridge Core terms of use, available https://www.cambridge.org/core/terms https://doi.org/10.1017/S1539299600004950 https://www.cambridge.org/core H - CO 3 o r t O H H - 0 0 H - 3 CO 1— ' a o o c 3 fD 3 r t CO O O 3 r t fD 3 1 3 0 i- i to i- i •< i S3 H - r t 3 * r t 3 * fD So C r t c r 0 i- i <* c r c r t r> o -a H - fD cn o H i CO O P l- i o fD 3 S " r t fD i- i H - (U 1— ' • S3 H - r t 3 * H i n> S3 fD * O fD 1 3 r t H - O 3 cn V ?3 3 * fu r t s: fD 3 * (U < fD O H i O i- i fD fD ? r p i CO r t i- i O 3 o 3 ^ i- i (D O O i- i D - CO r t 3 " P> r t S3 fD 3 - (B O tf p r t O C CD v ( B 3 C u S3 fD s c cn r t 9 p i N 4 fD r t 3 * ro 3 o CO r t O 3 r t H - ,n P H - r t ^ - rt 3 * fD cn H - r t C (B r t H - O 3 H - CO r t 3 * fD < fD l- i ^ 0 T J H i X ) r t 3 * fD H i i- i SB 0 0 3 fD 3 r t (B i- i >< J O CO H " r t fD • < fD l- l ^ 1— ' H - r t r t H 1 (D (B 3 O u r t 3 * fD i- i fD r t O H - I— 1 h -1 c cn r t i- i So r t fD 3 " H - cn 0 0 fD 3 fD i- i (B I— 1 r t 3 * fD O l- i ^ • O < fD i- i « 3 " fD H 1 3 H » 3 0 0 H - 3 3 C 3 c r fD i- i V (B 3 C u r t 3 " fD 3 - H - CO r t O i- i H - B » 3 CO H - 3 W 0 0 c r t S3 3 * fD 3 S fD r t C i- i 3 r t O r t P 1 fD 1— ' fD CO o C r t (B 3 H - 3 o H - (X ro 3 r t 3 " fD l- i fD 1 3 O CO cn H - c r i— • fD • M < (D 3 CO o y H - 3 r t P * fD 3 0 fa - ro rt 3 1 3 ro i- i H - o C u r t C T ro CO c l- i 3 r t CO O H i S3 3 * H - n 3 " P o l- i fD O o i- i C u CO CO P i- i 0 H - < ro V (B P C u p * ro 3 P CO r t (B O O fD 1 3 r t r t P * (B r t S3 P * ro 3 C T fD 3 * (B C O H i 1 3 O i- i c r i- i (D (B ? r H i (B cn r t r t O I- 1 (B O fD | 1 S3 H - I- 1 1— ' (B P C u V ! 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Carnegie Mellon University, on 06 Apr 2021 at 01:09:25, subject to the Cambridge Core terms of use, available https://www.cambridge.org/core/terms https://doi.org/10.1017/S1539299600004950 https://www.cambridge.org/core ASTRONOMY IN ANCIENT GREECE 5 copies of copies, laboriously and expensively made, and perhaps involv- ing one or even several translators. In most cases a work was never widely in demand, or if it was then the demand fell off with time, so that no copy has come down to us and the work is lost. This can apply even to works of the first importance, if their content is assimilated into a later and even more successful work. For then there is no longer any purpose in the potential reader's paying good money to recopy the earlier work, which therefore vanishes. This happened in Greek mathematics when Euclid's Elements synthesised the achievements of his mathematical predecessors: the writings of these predecessors thereupon vanished. But the historian of mathematics is lucky, in that Euclid wrote about 300 BC, when some of the greatest mathematicians of Antiquity were still to come. Ptolemy wrote his Almagest in the middle of the second century AD; he drew extensively on the work of his great predecessor Hipparchus, and so of the writings of Hipparchus we possess only one minor example. The very success of Ptolemy as a synthesiser, coming at the end of the high period of Greek astronomy, brought about the destruction of the works of even his greatest predecessors; and this apparent dearth of predecessors in turn enhanced Ptolemy's own stature in the eyes of later civilisations. With these preliminaries, let us quickly travel back in time from the present, beginning with a word about science and scientists in the modern world. We have at this General Assembly astronomers from every nation on earth, sharing in a common enterprise. There is world-wide agreement about what it is to be a scientist — what a scientist does, the questions he asks, the kind of answer that is acceptable, and the methods for arriving at such an answer and communicating it to other scientists. These agreements are inculcated in our education, and enforced by appointments committees to posts for teaching or research, by referees who control access to scientific journals, and by the electors to membership of scientific societies. Today this agreement is worldwide. But if we travel back in time to the year 1700, say, we find modern science only in western Europe. In England and France there are major scientific societies — the Royal Society and the Academie des Sciences — and scientific journals; scientific teaching posts in universities, and research institutions such as the Greenwich and Paris Observatories. Most important of all, there is the Principia of Isaac Newton which the eighteenth century would take as a model of a mature science. But the rest of the world has yet to learn from western Europe what science is. If we go back another hundred years, to 1600, we find no major scientific societies, no scientific journals, and only here and there a post where an astronomer or mathematician might make a career. But two men are at work whose achievements would set physical science on the path to Newton's Principia. Galileo would soon use the telescope to extend the range of the human senses, something no Greek would have envisaged, and he would become the first human being to see mountains on the Moon, and phases of Venus, the satellites of Jupiter, and so forth. Armed with this evidence against the old world-picture of at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S1539299600004950 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:25, subject to the Cambridge Core terms of use, available https://www.cambridge.org/core/terms https://doi.org/10.1017/S1539299600004950 https://www.cambridge.org/core 6 M. HOSKIN Aristotle and Ptolemy, he became a militant Copernican and set himself to create a physics in which it made sense for the Earth to be in motion about the Sun while we passengers on Earth are totally unaware of it. Kepler was a convinced Copernican from his youth, and he would soon use the accurate observations of Tycho Brahe to develope a profoundly new, dynamical astronomy within which each planet would orbit the Sun in a single curve, the ellipse studied by the mathematicians of Antiquity. In the work of Galileo and Kepler we find powerful new elements marking a fundamental advance beyond anything present in Copernicus only a few decades earlier. Copernicus's De revolutionibus (1543) is thoroughly Greek in spirit and method; it is very obviously modelled in layout on Ptolemy's Almagest, addressing the same problems and offering the same kind of answer by means of similar techniques. Indeed, in some ways it was more faithful to the totality of Greek natural philosophy and astronomy than was Ptolemy's Almagest. Copernicus was not the first of the moderns but the last of the medievals, and last of the astronomers in the Greek tradition; yet his claim that the Earth is a planet convinced both Kepler and Galileo and helped spark off the Scientific Revolution that taught first western Europe and then the whole world what science is. This, in brief, is why Greek astronomy is fundament- ally important in the whole history of science. The basic aim of Copernicus's De revolutionibus is to use combina- tions of uniform circular motions to provide geometrical constructions that would accurately reproduce the observed motion of each planet across the sky. He was, in fact, answering the challenge said to have been thrown down by Plato in the first half of the fourth century BC: "By the assumption of what uniform and orderly motions can the apparent motions of the planets be accounted for?" The assumptions underlying Plato's question are very remarkable indeed. First of all, the universe is assumed to be a cosmos. Today we do not link the astronomical term 'cosmos' with the cosmetics that a lady uses to perfect the beauty and harmony and symmetry of her appear- ance, but the root word is the same. A cosmos is first of all a rational universe, one that the human intellect can penetrate. It is not the domain of the gods with their whims and fancies, their play- things and their enemies, gods whose behaviour a mortal man can neither control nor predict. There can be a science of the universe because the universe is a cosmos. But a cosmos is not merely rational; it has beauty and harmony and symmetry. Copernicus found Ptolemy's treatment of the planets one by one unsatisfactory because there was no perception of the unity of the universe; the result of assembling the various independent bits would be, he said, "monster rather than man". Kepler, in his first publication, believed he had penetrated the mind of the divine geometer who created the universe, when he found that the planet- ary orbits were spaced out on the pattern of a nest of regular solids and spheres. The cosmos had a long and important history, and the conviction on the part of the early Greeks that the universe is a cosmos set the scene for the science of astronomy. at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S1539299600004950 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:25, subject to the Cambridge Core terms of use, available https://www.cambridge.org/core/terms https://doi.org/10.1017/S1539299600004950 https://www.cambridge.org/core ASTRONOMY IN ANCIENT GREECE 7 At the outside of the cosmos was the sphere of the heavens. We are so used to working with spherical geometry that we think it self-evident that the heavens appear spherical to the observer, but a study of other early civilisations shows that this is far from being the case. Curiously, at the other extreme, many people today are convinced that the spherical shape of the Earth is an early modern discovery and that explorers like Christopher Columbus feared they would sail off the edge of a flat Earth. In fact, the spherical shape of the Earth was known to Pythagoreans long before Plato, and in the writings of Plato's pupil, Aristotle, which were so central to medieval education, we have several proofs of this: that the shadow of the Earth during an eclipse of the Moon is always circular in outline, and that the stars are seen differently as we travel north and south. Indeed Aristotle quotes a value for the circumference of the Earth that is too large, but only by a factor of less than two. The Greek sense of symmetry demanded that the spherical Earth be at the centre of the spherical heavens, and there was nothing about the appearances to contradict this. Plato's challenge, therefore, assumed a cosmos that was lawlike, and comprised a spherical Earth at the centre of a spherical heavens. Now the stars goes round us every day, and since the Greeks were the boldest, not to say the most irresponsible of speculative thinkers, a number of early philosophers suggested that the Earth itself might be spinning or otherwise in motion. Since Aristotle's method of exposition is to give the views of others before giving his own, he sets out these theories, thereby ensuring that every medieval and Renaissance student of astronomy considered them too. But Aristotle, like other Greek writers, has one especially decisive argument against the motion of the Earth; and although it is not the custom in Invited Discourses to perform experiments, I would like to reproduce the Aristotelian test, and prove to you experimentally that the Earth is indeed at rest. I take this heavy stone, and I throw it straight up in the air. You will see that it falls back into my hand, and this proves that my hand did not move during the time that the stone was rising and falling. If the Earth had been in motion, and I and my hand with it, then my hand would have moved on in the second or two that it took the stone to rise and fall back again to the place from which it had been thrown. Instead, when it arrived back again, there was my hand, ready to catch it. To quote Aristotle: "heavy bodies forcibly thrown quite straight upward return to the point from which they started" (De caelo, 296b). (It goes without saying that post-Newtonian science provides a theoretical frame- work within which the experiment by no means proves that the Earth is at rest. Modern theory benefits from the heroic efforts of Galileo and others to make dynamical sense of Copernicus's claim. But as historians we have to see the experiment through Greek eyes, and interpret it within the context of their theory, not ours. Within that context, the experi- ment decisively proves the Earth is at rest.) Aristotle, even more than Plato, emphasises for us the contrast between Earth and heavens. On Earth there is coming to be and passing away, life and death, and this is reflected in the fact that natural at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S1539299600004950 Downloaded from https://www.cambridge.org/core. Carnegie Mellon University, on 06 Apr 2021 at 01:09:25, subject to the Cambridge Core terms of use, available https://www.cambridge.org/core/terms https://doi.org/10.1017/S1539299600004950 https://www.cambridge.org/core 8 M. HOSKIN movements (a stone in falling, smoke in rising) take place in a straight line, towards or away from the centre of the Earth, which is also the centre of the universe. And such movements are temporary: the stone stops falling when it has fallen as far as it can. By contrast, in the heavens everything is eternal, stars never appear or disappear, and this is expressed in their movements, regular uniform cyclic movements that of their nature continue endlessly without change. Mainstream Greek astronomy, then, accepted a spherical Earth at rest in the centre of a spherical sky, with almost all the stars rotating daily about the Earth with a common and unchanging cyclic motion. Almost all the stars, but not quite all. Seven stars seemed irregular, whimsical, lawless in their movements: namely, the Sun, the Moon, Mercury, Venus, Mars, Jupiter and Saturn. These were the 'wandering stars', in Greek planetes, 'planet'. These seven planets seemed exceptions to the otherwise regular and lawlike cosmos. Plato's challenge was to show that the seven wanderers are not true exceptions but are equally lawlike and geometrical and regular in their motions - in other words, that the regularity is there, though it is more complex than with the fixed stars. What kind of answer is Plato prepared to accept? The "uniform and orderly motions" he requires must in fact be combinations of uniform circular motions. Just as some recent cosmologists have insisted that a theory of the history of the universe must be without any special moment in time, because this is the way things must be, so Greek geometers and astronomers had a profound conviction that the heavens move with uniform circular motions: the cosmos simply is that kind of realm, and eternal, unchanging circular motions are the only motions so fundamental, so basic that of them no further questions can be asked. The challenge posed by Plato shows a mature attitude to astronomy as an intellectual enquiry: an apparent anomaly in an otherwise satisfactory theory is- to be resolved along agreed lines. The solution proposed by Plato's contemporary, the great mathematician Eudoxus, and preserved for us by Aristotle, is a brilliant mathematical tour de force; in that, although proceeding along what we know to be quite the wrong lines, Eudoxus generates the observed movements of each planet in qualitative outline by means of an elegant and simple geometrical construction. Each of the seven planets is thought of as attached to the equator of a sphere centred on the Earth and spinning about its poles with a uniform angular velocity. These poles are thought of as attached to a second sphere, outside the first and concentric with it, and spinning about different poles with a uniform angular velocity. The motion of the planet will of course be compounded from the motions of the two spheres. Outside the seoond sphere is a third, again centred on the Earth. The poles round which the second sphere spins are attached to the third sphere, which spins about yet another axis, and again with a uniform angular velocity. This completes the geometrical model for the Sun and at https://www.cambridge.org/core/terms. https://doi.org/10.1017/S1539299600004950 Downloaded from https://www.cambridge.org/core. 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E • H 4 -1 E o u 4 -4 C U X J CO S -l 6 0 0 S-l 4-1 0 1 S-4 o 4-1 4-1 • M 6 0 fi • H C O 3 CO C J CO CO i-4 i-H CU Es CO CO C U X J 3 4-1 • M 4-1 CO C X r-l E o C J C J • M 4-1 ex • H > -, r H CO en C J C U c • M c o • H 4-J O E cO S -i cu X I 4-1 o cu X I 4 -1 S -l o C M X I C J CO 0 ) S -l 3 o 4 -1 *. fi o o g X ) fi C O c 3 C O cu X I 4-1 S -l o 4 -1 en 0 1 S -l 0 1 X I C X C O cu cu S -l X i 4-1 X 4-1 • 1-1 3 • cu E • H 4-1 C M o i-4 CO 4-1 o 4-1 CO X I C U X I cu C U c CO 3 X o X I 3 w A en S-4 C O 4-1 en X I C U X • M C M cu X 4-1 S -l o 4 -1 C U c o X ) fi CO ». 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X i fi CX r-l en CO • e n 4 -1 4-1 O C U fi 4 J CO X I r-4 6 0 C X 3 o 0 ) X I X i 4 J 4-1 cu 4 -4 X o o en 4-J fi O en •r-l CU J J S -i o cu B x i ex C U en X I 4-1 CU en 6 0 C U C X I • M 4 -1 c S-l X I 0) fi > CU O 4-1 6 0 C • M en E $ 4-1 CO O r H . fi • en c cu > CO cu X I C U X 4-1 4 H o 01 S H 3 4-1 C J 3 S H 4-1 en r-4 cO • H S H C U 4-1 s E CU X 4-1 4-1 3 o X CO 6 0 c • H C O • M S H o cu X I 4-1 4-J o fi en CO Es >, r— 1 r H CO C J •r4 en > > X I C X CO cu u cu X I C X en 4 H o 4-1 C O cu fi X I C J CO C U 6 0 c • H r * CO E r. en •rH X 4J 0 X I 0 4-1 c 0 0 CO C O 9 Es C U r— 1 4-J 0 4-1 CO •rH S H < C U c o c cu 0 1 Es 4-1 C U X i en CU !H 0 1 X ex CO r 4-1 3 o 1 6 0 fi • M r H r H cu C J c CO o r. rH cfl c 0 •iH 4 J • H X ) X I C O 6 0 c •rH C J 3 X ) 0 S H 4 -1 c •rH X I c CO r— 1 CO cu SH g o X ) X ) cu 4-1 4-J • H s CO c CO S H 4 J C U X 4-> o c X ) r— 1 3 o Es CO fi o • M 4-1 o E X ) C U 4-1 c CO £ c 3 4-J cfl X 4-1 o en 4-1 X C U c CU X I 4-1 X I G CO 4-1 CO 0 1 G C O 0 1 S H cu X CX CO a • H S H 4-1 G C U C J c o C J C U en C U X I 4-J «l SH C U X I • • en o E CO o C J C U X 4-1 C M o G o • H 4-J cfl G cfl r-H C X X C U 0 1 exx: o CO o r H •rH X CX r— 1 CO SH 3 4-1 cfl G cu X I 4-1 o H • E cu 4-1 en 4 -1 SH o 4 H en •rH CO cfl X i cfl C O CO C U > •rH 4 J a cfl S H 4 -1 4-1 cfl >> > ^ r H CO C U X 4-1 X I 6 0 3 o M X I 4-1 X I G 3 0 C M o S H C X cu SH 0 1 Es s>» r-H S H cfl 0 1 r-H C J cu Es CO C O <*v X 4J SH cfl w . r H CO S H 4-1 c cu C J C U X I 4-1 4 J 3 0 X C fl r S r— 1 E S H o 4 H • H c 3 60 c • H G G • H S H cu X I 4-1 S H 3 4 H X I 0 1 X ) 0 1 C U fi i>. r-H X ) S H cO X i * c • H ex CO 0 4-J CO S -i cfl 4-1 en X I CU X •rH C M cu X I 4-1 4 H o 0 1 V 4 cu X CX en C U exx; C O en 0 ) S J CU X 4-1 O l > S H cu CO ex x CO o C M o M CO cu S H cu X 4-1 J3 4-1 •rH Es 0 1 X I 3 s en s s CU CO SH cu > •rH c 3 cfl X i C J 3 C O > . 4-1 c Q E u cfl X I c • H >, cu X I 4-1 0 1 S H S! 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P • a P p . ii 3 o CD CD P 1 3 < 3 li CD O P . en ft , CD 3 P CD O 3 - C D •< : ft , H c r 3 P O ft . p - " d o O CD X 3 3 O Q O en H i a s C C r t p CD C C en en CD CD O O 3 P > C C p - cn H i 3 CD 3 CD ii 3 en < O , • CD p O , 3 CD M 3 3 3 O r t ft , r t P CD p - P CD O P J ft . 3 ^ ^ en r t S3 O C T CD H i CD 1 3 P - c r 3 o cr cn CD O 1 3 r t cr p . CD 3 ii - cn CD n o 1 3 CD ii 3 p . o 3 p . en CD " P P p H 3 < < ft . p p - r t 3 CD r t p c r cn CD CD P - « 3 r t CD C C P , < P CD 3 3 •- r~'" th; tcmptation of Jes us. Luthcr·~ ~uffering in his cxilc, King Davi d's v,.inJcr in g. nnd, are parallel to the desire of the first-generation Plymouth colonists to have their children follow in their doctrinal footsteps , to define their identity not as colonists of a fertile land but as custodians of a legacy of persecution and suffering. Columbus's and Bradford's respective emphases on the exilie and nomadic condition of their pursuits result as much from the authority of the biblical intertext of Exodus as they do from the realization that the as-yet unclaimed American territoties in which they landed opened up a whole new horizon of possibilities for the economic and social a:melioration of their families and their churches. 18. For a detailed rcading of thi s passage that emphasizes Bradford's sensc of personal loss and bctrayal, see Franklin 168-69. 19. Jn a well-argued cssay on the various strands of Puritan utopianism, Peñalba García provides an apt summary of thc diluúon of Plymouth's ideals into those of Massachusetts Bay (130-35). Exiles andArrivals in Christopher Columbus and William Bradford 25 WORKSCITED Bercovitch, Sacvan. «Puritan New England Rhetoric and the Jewish Question.» Early American Literature 5 (1970): 63-73. - . The Rites of Assent: Transformations in the Symbolic Construction of America. New York: Routledge, 1993. Bradford, William. Of Plymouth Plantation, 1620-1647. Ed. Samuel Eliot Morrison. New York: Knopf, 1952. Cartelli, Thomas. «Transplanting Disorder: The Construction of Misrule in Morton 's New English Canaan and Bradford's Of Plymouth Plantation.» English Literal}' Renaissance 27 ( 1997): 258-80. Cummins, JOHN, ed. The Vóyage of Christopher Columbus: Columbus' Own Joumal Newly Restored and Translated. New York: St. Martin's, 1992. Fernández-Armesto, Felipe. Columbus. New York: Oxford UP, 1991. Franklin, Wayne. Discoverers, Explorers, Settlers: The Diligent Writers of Early America. Chicago: U of Chicago P, 1979. Gay, Peter. «William Bradford: Caesar in the Wildemess.» A Loss of Mastery: Puritan Historians in America. New York: Vintage, 1968. Hovey, Kenneth alan. «The Theology of History in Of Plymouth Plantation and lts Predecessors». Early American Literature 10 ( 1975): 47-66. Jehlen, Myra. The Literature of Colonization. The Cambridge History of American Literature. Volume One: 1590-1820. Gen. ed. Sacvan Bercovitch. New York: Cambridge UP. 1994. 11-168. Kadir. Djelal. Columbus and the Ends of the Earth: Europe 's Prophetic Rhetoric as Conquering ldeology. Berkeley: U of California P, 1992. Liss, Peggy K. Isabel the Queen: Lije and Times. New York Oxford UP, 1992. Meinig, D.W. Atlantic Ame rica, 1492-1800. The Shaping of America: A Geographical Perspective on 500 Hundred Years uf History. Vol. 1. New Haven: Yale UP, 1986. Nader. Helen. The Mendoza Family in the Spanish Renaissance, 1350-1550. New Brunswick: Rutgers UP, 1979. Pagden, Anthony. Spanish lmperialism and the Political lmagination. New Haven: Yale UP. 1990. Peñalba García, Mercedes. «Visiones eutópicas de América en la identidad colonial puritana.» RevistaAlicantina de Estudios Ingleses 2 (1989) : 127-42. Pérez, J oseph. La España de los Reyes Ca tólicos. 1986. Madrid: Información y Revistas, 1992. Rodríguez García, José María. «From the Communal "We" to the Individual 'T': The Rhetoric of Self-Legitimation in Berna! Díaz's Historia.» Revista de Estudios Hispánicos 31 (1997): 475-503. Varela, Consuelo, ed. Cristóbal Colón . Textos y documentos completos. Madrid: Alianza, 1982. Wenska, Walter P. «Bradford's Two Histories: Pattem and Paradigm in Of Plymouth Plantation». EarlyAmerican Litemture 13 (1978): 151-64. 26 José María Rodríguez García West, Dclno C. & August Kling, eds. The Libro de las profecías of Christopher Co/111nb11s: A11 en face Edition . Trans. and commcntary by West and Kling. Gainesville: U of Florida P, 1991 . Zagorin , Pérez. Societies. States, and Early Modem Revolutions: Agrarüm and Urban Rehelliom. Vol. l of Re beis and Rulers. 1500-1660. New York: Cambridge UP, 1982. Zamora, Margarita. «El prólogo al Diario de Cristóbal Colón ». Ínsula 522 (June 1990): 16-17. - . Readi11g Columhus. Berkeley: U of California P. 1993. work_6zqmg3eoezf4zllpqp7ght2lae ---- The ethics of innovation: Columbus and others try something new IA L McKneally Editorials D IT O R The ethics of innovation: Columbus and others try something new E Martin F. McKneally, MD, PhD When is it ethically acceptable to embark on an innovation that involves the life and health of human subjects? Our au- thors regularly submit new operations, devices, and man- agement techniques for publication in the Journal. Because professional journals and organizations are held accountable for their implicit endorsement of off-label and novel practices that prove to be dangerous or harmful, Editor Larry Cohn asked me to comment on the ethics of in- novation. I’ll begin and end with a case, describe an ethics framework for innovation, and recommend a practical approach that has served us well. THE CASE Christopher Columbus hypothesized that he could de- velop a shorter trade route to India by sailing straight west across the Atlantic. He was an experienced captain who had exceptional knowledge of ocean currents and celestial navigation. He had sailed as far west as the Canary Islands, 100 km off the west coast of Africa. During these innovative excursions, he did not fall off the edge of the world or en- counter the dragons depicted on maps of that era. The cur- rents off the Canaries, where he was alleged to have kept a mistress, ran westward toward an uncharted new world. Should Columbus have told the sailors he recruited that he was not planning to follow the navigational convention of sailing down the coast of Africa and around the Cape of Good Hope in constant sight of land? His seasoned col- league Pinchon, the captain of the Ni~na, advised recruiting seamen with the usual inducements—a good ship, good captain, rum, and the prospect of shared treasure—without mentioning the innovation of sailing an uncharted course. If Columbus insisted on full disclosure, Pinchon recommen- ded recruiting convicted prisoners with the promise of a royal pardon if they survived. Columbus retired to a mon- astery to seek consultation with the monks, pray for guid- ance, and make a decision. What should Columbus do? ETHICS FRAMEWORK Ethics is a plural noun. An ethic is a set of values, princi- ples, beliefs, and standards of conduct that guide the behav- ior of a specified group, such as journalists, lawyers, or From the Department of Surgery and Joint Centre for Bioethics, University of Toronto, Toronto, Ontario, Canada. Received for publication Dec 14, 2010; revisions received Dec 14, 2010; accepted for publication Jan 3, 2011. Address for reprints: Martin F. McKneally, MD, PhD, University of Toronto, 77 For- est Grove Dr, Toronto, ON M2K1Z4, Canada (E-mail: martin.mckneally@ utoronto.ca). J Thorac Cardiovasc Surg 2011;141:863-6 0022-5223/$36.00 Copyright � 2011 by The American Association for Thoracic Surgery doi:10.1016/j.jtcvs.2011.01.003 The Journal of Thoracic and Ca doctors. The ethic of surgery, with its foundational values of competence and commitment, is a singularly intense ver- sion of the ethic of medicine. The magnitude of the viola- tions of physical integrity and dignitary rights of surgical patients 1 and the immediacy of the surgeon’s personal en- gagement and responsibility contribute to this singularity. Surgeons take pains to explain in detail the goals, conse- quences, and expected outcomes of the surgical interven- tions they plan to perform. The variability of the terrain in which we practice leads to inevitable unplanned innovation: ‘‘We couldn’t remove the tumor, but we were able to bypass it,’’ or ‘‘We had only one donor lung, so we did a contralat- eral volume reduction on the recipient to maximize func- tion.’’ 2 Such innovations are morally justified in the court of professional opinion by their reasonableness, the lack of better alternatives, and their congruence with the values and principles of the surgical community. Planned innovations, like Columbus’ voyage, require definition and forethought. Innovation is a notional concept. There are many notions of its meaning, and no widely ac- cepted definition. To distinguish innovation from the minor incremental changes that surgeons introduce in the course of everyday practice, we have defined surgical innovation as ‘‘a new evolving intervention whose effects, side- effects, safety, reliability and complications are not widely known.’’ 3 This definition is intended to encompass transfor- mative rather than incremental changes. Although the boundary between minor incremental improvements and major transformative innovations is difficult to define, it is easy to recognize. McBurney’s decision to remove the ap- pendix through a small, muscle-splitting incision trans- formed the treatment of appendicitis. Prestigious advocates of traditional management, including William Osler, were adamantly opposed to his approach. McBurney thought that the conventional treatment—hot packs to the abdomen, morphine analgesia, turpentine enemas, rectal in- sufflation of tobacco smoke, and eventual drainage of the periappendicial abscess—was inadequate. Against the pre- vailing beliefs of medical and surgical colleagues, he devel- oped a bold new transformative treatment. The guidance documents on the ethics of innovation are reasonable but insufficient. For example, the Declaration of Helsinki 4 is the Journal’s reference standard; it autho- rizes us to try unproven treatments when nothing else works, to save life, re-establish health, or alleviate suffer- ing. ‘‘In the treatment of a patient, where proven interven- tions do not exist or have been ineffective, the physician, after seeking expert advice, with informed consent from the patient or a legally authorized representative, may use an unproven intervention if in the physician’s judgment it rdiovascular Surgery c Volume 141, Number 4 863 mailto:martin.mckneally@utoronto.ca mailto:martin.mckneally@utoronto.ca http://dx.doi.org/10.1016/j.jtcvs.2011.01.003 Editorials McKneally E D IT O R IA L offers hope of saving life, re-establishing health or alleviat- ing suffering. Where possible, this intervention should be made the object of research designed to evaluate its safety and efficacy. In all cases, new information should be re- corded and, where appropriate, made publicly available.’’4 The problem with this principle is that it allows innovation only where proven interventions do not exist or are ineffec- tive. Innovations in areas that might make the treatment cheaper, quicker, less debilitating, or easier to teach are ig- nored. We innovate to improve interventions that are al- ready in existence and effective but may be too expensive, slow, uncomfortable, or inconvenient. A thoughtful book, Ethical Guidelines for Innovative Surgery, 5 summarizing 5 years of study and 2 conferences on surgical innovation, addresses some of these issues. It will reward careful reading and provides a basis for further research. ETHICAL ISSUES SPECIFIC TO INNOVATIVE SURGERY An issue is an important social question to which there is often more than one reasonable answer. The important issues confronting innovators and those accountable for innovations are consent, validity, competence, conflict of interest, cost, and oversight. Consent The issue of consent is particularly sensitive and easily mismanaged. In a progressive society, procedures that are described as new are often presumed to be improvements relative to those that are older. Patients subjected to un- proven interventions should be explicitly informed about the innovation’s novelty and lack of a proven record of ef- fectiveness. Consent for the first patient to undergo heart surgery with cross-circulation is well described in G. Wayne Miller’s excellent book King of Hearts: The True Story of the Maverick Who Pioneered Open Heart Surgery. 6 ‘‘The Gliddens remembered their daughter LaDonnah, who had been born with the same [ventricular septal] defect.. They were willing to try almost anything to spare their baby Gregory their daughter’s fate.’’6 In obtaining their con- sent for a landmark innovative operation, ‘‘[Walt] Lillehei told the Gliddens that his ‘‘artificial heart’’ was actually an- other person—in fact, one of them. [He] drew a diagram of cross-circulation and talked of his experimental success with dogs.’’ 6 In contrast, many innovators are tempted to take the easy and less transparent approach, saying simply, ‘‘We have a new [and, by implication, better] way to do your operation.’’ Participants undergoing innovative interven- tions should be informed of the novelty of the undertaking. Validity The issue of validity is less settled with innovation than with accepted standard procedures, although many of the 864 The Journal of Thoracic and Cardiovascular Surg latter remain unvalidated. Valid interventions are effective, well-founded, and able to produce the desired result. The word valid derives from the Latin validus, meaning strong. An innovation may be presumed to be valid if it is founded on reasonable evidence of feasibility and effectiveness. This evidence may come from unplanned successful experience in an emergency, studies in animals, or demonstrations in the anatomy or pathology laboratory. Further support may come from the experience and endorsement of peers work- ing with similar frontier technologies and techniques. Intro- duction of an innovation is ethically justified on the grounds of probable validity, as judged by competent professionals. This remains a claim until validating evidence has been de- veloped with the help of well-informed, willing patients. Successful application in their care provides the basis for eventual recognition of the innovation as a validated com- ponent of the surgical armamentarium. Competence A foundational element of the surgical ethic is compe- tence to perform the appropriate surgical intervention with a high probability of success and a low risk of compli- cations. Many innovations challenge the competence of the surgical team. The learning curve—the progression in knowledge and skill in performance of innovative procedures—should be managed collaboratively with col- leagues under professional oversight. 7 There is an addi- tional issue of the impact on training. As teachers work on mastering new techniques, such as robotic cardiac sur- gery or video-assisted thoracic surgery, the operative expe- rience of their residents and fellows is inhibited. In some instances, gaining sufficient confidence to teach new proce- dures can take a year or longer. Conflicts of Interest Conflicts of interest arise in ‘‘situation(s) in which an in- terest (financial, personal, political) can interfere with a duty.’’ 8 The financial, personal, or reputational interests of innovative surgeons can compete with their fiduciary duty to put patients’ interests first. The temptation to in- crease market share, academic credit, or personal notoriety may lead to overuse or less attention to the cost of new tech- nology. Professional oversight can help to manage this risk. Cost The issue of cost arises because innovations in health care have been linked to the rapid rise in the cost of health care, potentially disadvantaging such other priorities as educa- tion and highway safety. Technologic innovation is believed to be responsible for the rise of the cost of health care at 2 to 3 times the rate of inflation. At hospitals emphasizing fron- tier technologies, the rate may be substantially higher. This conflict is an issue in societal justice, not simply a hospital management problem. ery c April 2011 McKneally Editorials E D IT O R IA L Oversight The issue of oversight requires special consideration. Re- sponsibility for ensuring that consent, validity, conflicts of in- terest, and cost are managed correctly is a professional issue. The chief of service and the institutional trustees are held publicly accountable when innovations go awry. Although some institutions delegate responsibility for oversight to in- stitutional [ethics] review boards or research ethics boards, innovation is not research. There is a family resemblance between them, arising from their experimental nature. Research is designed to produce generalizable knowl- edge, with carefully controlled methods for patient selec- tion and treatment assignment and with specified uniform techniques and outcome measures. The conduct of research is specified in predetermined, agreed, approved protocols to minimize the effects of chance variables. In contrast, the methods, patient selection, technical steps, and manage- ment are constantly evolving during the development of an innovative surgical procedure (Table 1). The innovators’ question is, ‘‘How can we make this work?’’ With time, pa- tient selection, management approaches, instrument modifi- cations, and techniques evolve. When all these have been settled, formal research can be undertaken to test hypothe- ses about the innovation, to answer the question, ‘‘Is this better than the standard approach?’’. Almost every major advance in medicine and surgery has been introduced through the pathway of innovation. Anes- thesia, antibiotics, arthroscopy, aneurysmectomy, and aortic valve replacement exemplify only a few of the a’s. Innova- tions can be hypothesis generating, but formal research to compare the outcomes with conventional treatment follows relatively rarely. THE CASE REVISITED Columbus did disclose his novel plan to the men he re- cruited. Unlike Pinchon, he reasoned that they should not all be thought of as identical members of a single category, with identical attitudes toward risk. This wise decision gave more risk-averse candidates, or those with pregnant wives or aging parents, the opportunity to opt out of a heroic ad- venture with unknown risks. Rejection of Pinchon’s prisoner proposal may have saved Columbus’s life. When the voyage stretched longer and lon- TABLE 1. Innovation versus research Innovation Research Techniques Evolving Defined Outcome measures Evolving Defined Patient selection Evolving Defined Conclusions Tentative, particular Generalizable Oversight Professional Societal (institutional review board, research ethics board) The Journal of Thoracic and Ca ger and the crew became restless, some turned against the captain, considering mutiny. If he had chosen criminals, with their ingrained distrust of authority and advanced edu- cation in violence, he might not have lived to celebrate his discovery of Hispaniola and the new world. HOW WE INTRODUCE SURGICAL INTERVENTIONS At several of the teaching hospitals at the University of Toronto, a helpful ‘‘Enabling Innovation’’ protocol has been in place for several years. 9 1. The surgeon initiates an ‘‘Enabling Innovation Let- ter’’ to the Surgeon-In-Chief (SIC), describing the in- novative procedure or device, the rationale for the request (including expected benefits, risks, and costs), and the names of 2 informed colleagues who endorse the validity of the proposal. These may be internal or external advisors whom the SIC can consult if needed. 2. The surgeon pledges to add the ‘‘Columbus Clause’’ to the standard consent form: ‘‘Iunderstandthatthistreat- ment is new to this hospital. I will be one of the first [x] patients to receive it here. I have been offered the stan- dard treatment. My doctors and nurses are working to find the best way to perform the new treatment and learn which patients will benefit most from it.’’ 3. If needed, the SIC consults members of an unconv- ened innovation task force of nursing, anesthesia, en- gineering, ethics, and legal personnel who are familiar with the Enabling Innovation pathway. 4. The SIC shows the letter and consent form to the chair of the research ethics board, who accepts or advises full review. This step proved useful in the early adop- tion phase of the policy. The research ethics boards no longer consider this necessary unless the SIC decides it is appropriate. 5. The innovator reports the outcomes of the first patients treatedtotheSIC,withhelpfromhospitaldatamanagers and cost estimates from the operating room manager. 6. Formal research is initiated if and when appropriate. Like Columbus’ sailors, patients are not identical mem- bers of a single category with identical attitudes toward risk. Some are intensely risk averse, some are foolishly ad- venturous, and some are heroes who are well suited to partic- ipate in advancing the frontier of medical science. Because the risks and outcomes of innovative surgical procedures are not always predictable, it seems fair and responsible to use more thorough procedures for disclosing the uncer- tainties associated with innovative surgical interventions. In summary, surgical innovations should be able to meet ethical standards of appropriate consent (including disclo- sure of their novelty), validity, competence, management of the conflicts of interest that might encourage their over- use, assessment of the impact of their cost on institutional or rdiovascular Surgery c Volume 141, Number 4 865 Editorials McKneally E D IT O R IA L societal resources, and oversight to ensure that the consent, validity, conflict of interest, and cost criteria are managed correctly. Bryce Taylor, Jacob Langer, John Wedge, and Randi Zlotnik- Shaul contributed to the development of the Enabling Innovation policy. Deborah McKneally made helpful revisions to the manuscript. References 1. McKneally MF. Managing expectations and fear: invited commentary on ‘‘Inde- cency in cardiac surgery: a memoir of my education at a super-esteemed medical place (SEMP),’’ by Dr. Edmund Erde. J Card Surg. 2007;22:49-50. 2. Todd TR, Perron J, Winton TL, Keshavjee SH. Simultaneous single-lung trans- plantation and lung volume reduction. Ann Thorac Surg. 1997;63:1468-70. 866 The Journal of Thoracic and Cardiovascular Surg 3. McKneally MF, Daar A. Introducing new technologies: protecting subjects of sur- gical innovation and research. World J Surg. 2003;27:930-5. 4. World Medical Association. WMA declaration of Helsinki ethical principles for medical research involving human subjects [Internet]. Ferney-Voltaire, France; 2008. Available at: http://www.wma.net/en/30publications/10policies/b3/index. html. Accessed January 30, 2011. 5. Reitsma AM, Moreno JD. Ethical guidelines for innovative surgery. Hagerstown, MD: University Publishing Group; 2006. 6. Miller GW. King of Hearts: the true story of the maverick who pioneered open heart surgery. New York, NY: Random House; 2000:4-6, 107. 7. McKneally MF. Video-assisted thoracic surgery: standards and guidelines. Chest Surg Clin North Am. 1993;3:345-51. 8. Khushf G, Gifford R. Understanding, assessing, and managing conflicts of interest. In: McCullough LB, Jones JW, Brody BA, eds. Surgical ethics. New York, NY: Oxford University Press; 1998:342-66. 9. McKneally MF. Editor’s column: enabling innovation. Univ Toronto Surg Spotlight [Internet]. Winter 2005-2006:15. Available at: http://www.surgicalspotlight.ca/ Shared/PDF/Winter06.pdf. Accessed January 30, 2011. ery c April 2011 http://www.wma.net/en/30publications/10policies/b3/index.html http://www.wma.net/en/30publications/10policies/b3/index.html http://www.surgicalspotlight.ca/Shared/PDF/Winter06.pdf http://www.surgicalspotlight.ca/Shared/PDF/Winter06.pdf Outline placeholder The case Ethics framework Ethical issues specific to innovative surgery Consent Validity Competence Conflicts of Interest Cost Oversight The case revisited How we introduce surgical interventions References work_73mz2gwtyrehxbaljpxgm5h3ne ---- Brit. 7. vener. Dis. (1974) 50, 169 Changing patterns of treponemal disease R. R. WILLCOX* St. Mary's Hospital, London, and King Edward VII Hospital, Windsor It has been postulated that T. pallidum of syphilis arose originally from free-living treponemes in mud, of which T. zuelzerae still remains representative (Veldkamp, 1960). These organisms then came to be carried commensally by man, as are the dental treponemes today. Disease syndromes then developed as natural selection ensured the optimal survival of mutants most likely to produce the lesions best suited for onward transmission from host to host in the prevailing environment (Willcox, 1972). The three treponemes which are pathogenic to man are T. pallidum, the cause of venereal and non- venereal syphilis, T. pertenue of yaws, and T. carateum of pinta, all of which have a similar morphology and evoke so-far indistinguishable antibodies in infected persons. In animals, T. cuniculi has evolved sep- arately in the rabbit in which it is responsible for a naturally occurring venereal disease (cuniculosis), while a more recently discovered member of the group, T. Fribourg-Blanc, has been isolated from monkeys in yaws areas (Fribourg-Blanc, Niel, and Mollaret, 1963). Of the treponematoses affecting man, venereal syphilis is ubiquitous, yaws is a disease of the tropical belt, endemic syphilis is encountered in adjacent dry areas, while pinta is confined to the Central and South Americas. Evolution of pinta It has been postulated (Cockburn, 1961; Hackett, 1963) that pinta was the first treponematosis to evolve within the Afro-Asian land mass, from which it gained world-wide distribution, finally persisting amongst underprivileged peoples in the remoter areas of the Central Americas and the Northern part of the South American continent-being most prevalent today in Mexico, Colombia, Peru, Ecuador, and Venezuela. Some i million cases of pinta were Received for publication October 15, 1973 Presented at the II Venezuelan Congress of Dermatology, Caracas, Venezuela, in September, 1973 *Member of the W.H.O. Expert Panel on Venereal Infections and Treponematoses believed to exist 20 years ago (Guthe and Willcox, 1954). The understanding of this disease owes much to the pioneering work of Herrejon (1938) and later of Varela and others in Mexico (Rein, Kitchen, Marquez, and Varela, 1952); Guimaraes, Rodriquez, Costa, Silva, and Padilha Goncalves in Brazil; Leon Blanco in Cuba; and Sainz in Ecuador. In Venezuela it has been studied by Iriate, Rossi, and others but particularly by Dr. Martin Vegas, Honorary President of this Congress, and its Co- ordinating Secretary, Dr. Rafael Medina. Dr. Medina has been described (Smith and 14 others, 1971) as 'the world authority on the non-venereal treponematoses having had more experience with clinical yaws and pinta than virtually any other living physician'. He has contributed much to our knowledge of cross-immunity between the tre- ponematoses (Medina, 1967), and with Dr. Kuhn and colleagues in Atlanta has successfully established the disease in the chimpanzee (Kuhn, Medina, Cohen, and Vegas, 1970). The lesions of pinta virtually only affect the skin (apart from the odd juxta-articular node) although a case with co-existing interstitial keratitis has been described (Smith and others, 1971). It starts with an initial lesion, and subsequently satellite or more remote skin lesions (pintides) of various hues develop, which may be pink, brown, blue, and black, finally becoming white or achromic. It is spread by direct skin contact amongst poor peoples, particularly in the lower age groups. Half of the series of Rein and others (1952) comprised persons below 15 years of age. Evolution of yaws It has been considered that yaws evolved from pita as a humid warm environment developed in Afro- Asia. The new climate, resulting in much local moisture from sweating, favoured the production of exuberant skin lesions containing vast numbers of treponemes such as are found in the papillomata, nd other infective manifestations characteristic of fram- boesia or yaws (Hackett, 1957). The surface lesions of o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://sti.b m j.co m / B r J V e n e r D is: first p u b lish e d a s 1 0 .1 1 3 6 /sti.5 0 .3 .1 6 9 o n 1 Ju n e 1 9 7 4 . D o w n lo a d e d fro m http://sti.bmj.com/ 170 British Journal of Venereal Diseases yaws, like those of pinta, may remain infective for long periods of time. The absence of clothes with resultant liability to trauma, which facilitates the entry of the organism, and person-to-person contact of sweaty skins in a tropical environment, facilitated its rapid spread amongst primitive communities and its very contagiousness ensured that it was mainly a disease of childhood. Through the centuries yaws has been one of the world's most prevalent infections, which for practical purposes had been contained between the Tropics of Cancer and Capricorn although with modern travel the occasional case may be encountered in temperate zones (Fig. 1). Before the WHO-assisted mass campaigns were extensively mounted, it was esti- mated that some 50 million cases existed, half of them in Africa (Guthe and Willcox, 1954). In these campaigns against the endemic treponematoses organized by WHO in 46 countries, the prodigious total of 160 million people has been examined and 50 million treated with penicillin as clinical cases of yaws or endemic syphilis, or as latent cases or contacts (Guthe, Ridet, Vorst, D'Costa, and Grab, 1972). The incidence of the disease has been reduced to extremely low levels in many areas (e.g. from 2-95 to 0 005 per cent. of clinically active cases in Western Samoa), although continued seroreactivity to tests with treponemal antigens has suggested that the disease continues to be transmitted in the community, possibly at a subclinical level. It is stated that early infectious cases are now virtually eliminated from Venezuela. Yaws, unlike pinta, can have more serious compli- cations remote from the skin, such as early osseous involvement and late gummatous manifestations. Although not thought to have cardiovascular or neurological complications, or to be transmitted to the fetus, in the so-called Caracas project, Smith and others (1971) found ocular abnormalities, raised immunoglobulin levels in the cerebrospinal fluid, and treponemes in the aqueous humour of some patients with late yaws. Evolution of endemic syphilis A further development followed in the more arid regions bordering on the yaws areas where the still very warm but now dry climate, frequently cold at night, necessitated the wearing of clothes, thus preventing skin-to-skin transmission. Only organisms producing lesions of the mucous membranes could now survive by means of direct transmission by kissing, or indirectly through the intermediary of common eating or drinking vessels (Grin, 1953) or fingers (Guthe and Luger, 1957), although condy- lomata lata and skin lesions are encountered, parti- cularly in moist areas. Because infection tended to occur before puberty, sexual spread was seldom noted as by the time the children were old enough for sexual intercourse they had already acquired the disease. In all of the endemic treponematoses, there is the vicious circle of poverty creating disease and disease creating poverty (Fig. 2). Endemic syphilis acquired prominence when it was described usually in desert or near-desert regions in a number of Middle-Eastern countries under the name bejel (Hudson, 1928; Csonka, 1952) or balash. It is also found today in Africa in countries FIG. 1 Primary dark-field positive yaw on ankle of West Indian child who had been resident in Londonfor only a few months o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://sti.b m j.co m / B r J V e n e r D is: first p u b lish e d a s 1 0 .1 1 3 6 /sti.5 0 .3 .1 6 9 o n 1 Ju n e 1 9 7 4 . D o w n lo a d e d fro m http://sti.bmj.com/ Changing patterns of treponemal disease 171 only at the end of the 15th century, when Christopher Columbus and parts of the Americas were unfairly incriminated. Like other sexually-transmitted diseases the inci- dence of venereal syphilis has been high in times of war, and the period during and immediately after the second war was no exception. The more settled conditions of peace and the introduction of effective treatment with penicillin led to a dramatic fall, but in the past 10 to 15 years numbers have again risen in many countries although in most they remain at less than one-tenth of the wartime peak. F IG. 2 Vicious circles of endemic treponematoses bordering on the Sahara desert in the North (Basset and Boiron, 1965), and it has also been found in the South adjacent to the Kalahari desert in present-day Rhodesia-where under the name njovera it was observed by the author when making a survey (Willcox, 1951a, b), and in adjacent Botswana (Murray, Merriweather, Freidman, and de Villiers, 1956). It also still exists in the Karoo in the Transvaal (Du Toit, 1969) and in the North-Western Cape areas, and has recently been observed around Bloemfontein (Scott and Lups, 1973). In these areas gangosa-like lesions and other late complications may be encountered. The 'give-away' sign of its existence is the finding of a nipple chancre in a mother caused by her infected child. Foci of endemic syphilis were present in Europe, in Bosnia, Yugoslavia, even after the second world war, but have since been successfully eradicated by mass campaigns (Grin and Guthe, 1973). Between the wars it extended over wide areas of the Southern U.S.S.R., Turkey, and the then Palestine. There are also many historical examples, including the sibbens of Scotland, the button scurvy of Ireland and the radesyge of Norway (Lancereux, 1868). Emergence of venereal syphilis Venereal syphilis develops from endemic syphilis as social advance limits transmission between children; as the children grow up they are then susceptible to its sexual transmission (Willcox, 1960). With this trend some unhygienic habits still persist (e.g. sharing of pipes and toothpicks, widespread mouth- to-mouth kissing, wet nurse practices, etc.), and both venereal and non-venereal syphilis exist together, the former being found in the older age groups in those who have not experienced the childhood infection. It is considered probable that endemic syphilis was once widespread in non-tropical regions including Europe, where it was recognized as a venereal disease Continuing evolution of syphilis EFFECTS OF DETERIORATING ENVIRONMENT Changes in the distribution, severity, clinical ap- pearances, and other features of syphilis still continue as man's habits and environment alter for the better or worse, particularly since the introduction of penicillin and other antibiotics. The gradually extending process of urbanization has itself contri- buted to the waning of pinta, yaws, and endemic syphilis in many areas, but a reversal of this process is possible and is reported from time to time when social conditions deteriorate and infections once again occur among children. Such a reversal from venereal to non-venereal syphilis has been recorded from a number of coun- tries even in the penicillin era (Murrell and Gray, 1947; Fejer, 1948; Eisenberg, Plotke, and Baker, 1949; Rajam and Rangiah, 1952; Rees, 1954; Taylor, 1954). A more recent experience was described by Luger (1972); three children were infected in a crowded ex-barrack building in Vienna, although the room occupied by the family of nine also contained the luxury items of a refrigerator, television set, record-player, and two transistor radios. With the present population explosion and increasing accommodation difficulties, including the unwelcome growth of shanty towns near to modem cities in many parts of the world, such small-scale reversals of treponemal evolution are to be expected from time to time. EFFECTS OF PENICILLIN Action of penicillin This antibiotic acts during the growth and division of T. pallidum and related treponemes when the cross-linked chains of N. acetyl glucosamine and N. acetyl muramic acid, which form a matrix in the outer cell wall to contain the inner protoplast like o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://sti.b m j.co m / B r J V e n e r D is: first p u b lish e d a s 1 0 .1 1 3 6 /sti.5 0 .3 .1 6 9 o n 1 Ju n e 1 9 7 4 . D o w n lo a d e d fro m http://sti.bmj.com/ 172 British J7ournal of Venereal Diseases the outer skin of a football (Fig. 3), are breached by the hydrolytic action of a lysozyme manufactured by the organism (Fig. 4). The enlarging gap is restored |Transpeptidasel Mureine precursors INN* / 00; l ITranspeptidasel fZAP FIG. 5 Cell wall biosynthesis. Stage two a N-acetyl-muramic acid ( N-acetyl.glucosamine FIG. 3 Mureine structure of T. pallidum cell wall after Pelzer (1967), Kern (1972), and Luger (1973) FIG. 6 Cell wall biosynthesis. Stage two M FIG. 4 Cell wall biosynthesis. Stage one (after Luger (1973) andKern (1972)) by means of mureine precursors, which pass through the cytoplasmic membrane of the protoplast to be reconstituted through the action of several enzymes including carboxypeptidases and particularly trans- peptidase (Fig. 5). These enzymes affect the strength- ening cross-bondings between the adjacent reforming chains (Pelzer, 1967; Kern, 1972; Luger, 1973) (Fig. 6). By the affinity of penicillin for these enzymes, particularly transpeptidase (Fig. 7), and by inter- fering with the proper assembly and production of the mureine precursors, the antibiotic prevents their effective peformance, thereby allowing the un- affected lysozyme to continue to breach the cell wall more quickly than it is being renewed. Internal osmotic pressure will then cause the protoplast to bulge through the rent in the outer casing and this may ultimately burst or destroy the organism (Fig. 8). Effectiveness of penicillin Penicillin has been shown to be effective in the treatment of early infections with pinta, yaws, and syphilis, both endemic and venereal, even in single injections of the right preparation, notably procaine penicillin in oil with aluminium monostearate (PAM) and benzathine penicillin. There are no signs that T. pallidum is becoming resistant to penicillin, although the inability to culture the virulent organism in vivo makes precise assessment of this point impossible (Schamberg, 1963). The antibiotic has proved virtually 100 per cent. successful in the incubation period, when it is widely used for epidemiological treatment, and in seronega- tive primary syphilis; in serpositive primary and in secondary syphilis the clinical results are excellent, with re-treatment rates around 3 to 10 per cent., and even then many such recurrences are probably re-infections (Idsoe, Guthe, and Willcox, 1972). Seroreversal of reagin tests is the rule, although the treponemal immobilization and FTA-ABS tests may continue to show reactivity which may or may not be associated with persistence of the organism. In the late infection gummata quickly heal and good results are also obtained in neurosyphilis with o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://sti.b m j.co m / B r J V e n e r D is: first p u b lish e d a s 1 0 .1 1 3 6 /sti.5 0 .3 .1 6 9 o n 1 Ju n e 1 9 7 4 . D o w n lo a d e d fro m http://sti.bmj.com/ Changing patterns of treponemal disease 173 ,-Lactam ring l (3NH-CH-CH/ \Co3I-CLH C7- N CH-COO-( |Transpeptidase I + HOH -CH-CH- O=C7 N- |Transpeptidase | FIG. 7 Action of penicillin Lysozyme 'dose s Penicillin Penicillin - Tra nspeptidase FIG. 8 Action of penicillin meningeal involvement. The outcome is less striking in parenchymatous neurosyphilis, in cardiovascular syphilis, and in complicated late congenital syphilis. In late latent syphilis, and indeed in late syphilis as a whole, seropositivity usually persists, although future complications are largely prevented. Changes in the clinical pattern There have been striking changes in the clinical manifestations of syphilis since the introduction of penicillin. Exuberant secondary lesions of skin and mucous membranes are now rare in many areas as are ulcerative skin lesions, and syphilis seems to be becoming a milder disease. This may be partly due to better nutrition and to better standards of hygiene which may well explain the decline in the prevalence of condylomata lata. However, it would not be unreasonable to suppose that the disease would become milder under 'antibiotic bombardment', as those strains of the organism which did not draw attention to themselves by provoking a marked host response would be those more likely to survive. In the untreated disease approximately one- quarter of the patients used to undergo secondary infectious relapse (Gjestland, 1955) but today this is seldom seen. Likewise the total incidence of late complications are observed to fall wherever figures are compiled (Kiraly and Causse, 1973). Gummata, which were at one time rife-especially when the incidence of early infection was high (Grin, 1953)- have virtually disappeared in many places; at St. Mary's, where around 10 per cent. of the annual total of cases of early syphilis in England and Wales are encountered, a year or more may pass without a gumma being seen. Early congenital syphilis has also become very rare, infection in the child having been prevented pre-natally or cured by penicillin while still in utero. On the other hand, as penicillin is so quickly effective, re-infections with syphilis, at one time seldom encountered, are now common. In 1972, of 165 patients with early infectious syphilis seen at St. Mary's, 22 (13 3 per cent.) had experienced 26 earlier attacks of the disease, in eighteen instances 3 o 11 years previously. Persistence of treponemal forms After very painstaking examinations Collart, Borel, and Durel (1962), in France, found treponemal forms in the lymph glands and cerebrospinal fluid of both penicillin-treated rabbits and humans who had not been treated early in the disease. They were later found in the cerebrospinal fluid of patients with untreated and treated late syphilis (Rice, Dunlop, Jones, Hare, King, Rodin, Mushin, and Wilkinson, 1970) and also in the aqueous humour (Smith and Israel, 1967) and more recently in Venezuela in patients with yaws (Smith and others, 1971). In only a few instances have these organisms been passaged in rabbits (Turner, Hardy, and Newman, 1969), but animals which have received passaged material may develop positive serological reactions to trepo- nemal antigens and some of these have later been shown to carry treponemes (Yobs, Clark, Mothershed, Bullard, and Artley, 1968). This phenomenon could be related to the occurrence of such reactions amongst apparently normal children in yaws areas where near-eradication of the early clinical disease has apparently been achieved by mass treatment (Guthe and others, 1972). While some doubt exists as to the significance of these organisms, e.g. whether they are derived from the mouth or other sources, the possibility remains that they are T. pallidum which have not been over- come by the low levels of penicillin commonly encountered in the fluids in which they are found or which may have survived as 'L' forms. These have been observed for some years with cultured tre- ponemes in an unfavourable penicillin environment, and have also been observed in syphilitic tissues o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://sti.b m j.co m / B r J V e n e r D is: first p u b lish e d a s 1 0 .1 1 3 6 /sti.5 0 .3 .1 6 9 o n 1 Ju n e 1 9 7 4 . D o w n lo a d e d fro m http://sti.bmj.com/ 174 British Journal of Venereal Diseases under the electron microscope (Ovcinnikov and Delektorskij, 1971). Collart, Franceschini, and Durel (1971) believe that, if penicillin treatment is given during the first 3 months of a syphilitic infection, the treponemes disappear and there is no persistent reactivity to the TPI test. In infections of 2 or more years' duration, treponemes are still found after penicillin therapy. Lymph node transfer tests are positive in about 5 per cent. of such cases and cortisone therapy can activate some infections to produce clinical lesions. It is postulated that, in the latent period, the untreated host develops resistance so that the parasites vegetate in a commensal state, but the possibility cannot be excluded that under unknown biological conditions they may recover their virulence. Venereal syphilis fills treponemal disease vacuum In areas where near-eradication of yaws has been achieved by mass campaigns or by advancing civilization resulting in urbanization and the wearing of clothes, the herd immunity to syphilis due to past yaws is now removed and venereal syphilis tends to take its place. Such an event has been reported in Tahiti (Van der Sluis, 1969), Western Samoa (Guthe and others, 1972), and in New Guinea (Rhodes and Anderson, 1970; Bell, 1971). The writer has had the good fortune to witness the situation in New Guinea. Here venereal syphilis has spread through the centre of the country along the new highway, in some parts a rough winding mountainous road, which extends from the port of Lae in the east to Mount Hagen in the Western Highlands. Syphilis did not exist in this area up to 3 years or so ago, although gonorrhoea was prevalent, as was yaws until a mass campaign was undertaken in 1957. Today syphilis is being carried by the truck-drivers and the so-called 'passenger-meris', who prostitute themselves in the villages along the route and with the drivers in their journeys to and from more prolonged prostitutional activities in Lae. The dissemination of the disease amongst the local population is in proportion to the prevailing sexual freedom, the spread being most extensive amongst the promiscuous Chimbu. In the male, primary chancres are encountered in half the clinical cases, although many are atypical. Most of the remainder of clinically affected males show condylomata lata, sometimes in the axillae (Fig. 9). In the female, secondary condylomatous lesions are usual but primary lesions are sometimes observed. Secondary rashes are only occasionally encountered but maybe these by themselves do not FIG. 9 Condylomata lata in the axilla (Courtesy of Bell, 1971) prompt patients to seek treatment. The same applies to oral mucous patches. Treponemes resembling T. pallidum can be found in the lesions. Donovanosis (granuloma inguinale), of which the number of reported cases exceeds 40 per cent. of the reported cases of syphilis in adjacent Papua, need cause no confusion when the lesions are extensive, and can be confirmed by appropriate pathological tests, but may well do so when no darkfield tests for treponemes or smears for Donovan bodies are made. Thus, even now, towards the end of the 20th century, an opportunity still exists of observing the rapid 'syphilization' of a susceptible community. EFFECTS OF MAN'S BEHAVIOUR Population movement All the treponematoses have been distributed during mass migrations (Hudson, 1965), including religious pilgrimages (Hudson, 1963), and the African slave trade (Hudson, 1964). The role of the seaman and soldier in the spread of syphilis and other sexually- transmitted diseases is traditional. In modern times, of no less importance are migrations in search of work or fleeing from oppression, and latterly the 'travel explosion' of tourists (Guthe and Willcox, 1971). It is estimated that there are now more than six million migrant workers in Europe alone, 20 to 30 per cent. of whom return to their countries each year to be replaced by more recruits. The world figure for tourists in 1971 was around 170 million, approxi- mately three-quarters involving Europe (WHO, o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://sti.b m j.co m / B r J V e n e r D is: first p u b lish e d a s 1 0 .1 1 3 6 /sti.5 0 .3 .1 6 9 o n 1 Ju n e 1 9 7 4 . D o w n lo a d e d fro m http://sti.bmj.com/ Changing patterns of treponemal disease 175 1972). These movements, and the accompanying social circumstances, make possible a far greater international exchange of syphilis and other venereal diseases than ever before and, in the case of the tourist, the diseases may be brought home to the smallest towns and villages. Increased promiscuity With greater opportunity for the two sexes to meet without supervision and with the removal of pre- viously inhibitory influences, there has been an increase in promiscuity, both heterosexual and homosexual. Quite small increases in promiscuity can have alarming effects in closed groups. In any 'closed' group of any size, it only needs one additional outside sexual link to introduce venereal disease, possibly to all. This can happen in groups in which half or even two-thirds have only one sexual partner (Willcox, 1973) (Fig. 10). 2/3 of this qroup have only one consort yet one outside link could result in all infected It is presumed that the numbers of different contacts per unit of time has increased, although there are no firm data to support or refute this. Certainly anal chancres are a more commonly recognized presentation of early syphilis today, although it might be argued that previously they were frequently missed. Although many individual physicians have presen- ted data concerning the incidence of homosexual infections, there are few nation-wide data. One such study has been recently undertaken in the United Kingdom (British Cooperative Clinical Group, 1973), in which 176 clinics in 153 towns and cities participated and the cases included comprised 90 per cent. of the reported national totals of primary and secondary syphilis treated during the year, and 86-1 per cent. for gonorrhoea. Of the total of 924 male infections treated, 532 penile infections were believed to have been hetero- sexually acquired and 172 homosexually; 220 infections were anorectal. Thus homosexuals were responsible for 42-4 per cent. The percentage was highest (45 -9 per cent.) in England, those for Scotland and Wales being 13-5 and 9 5 per cent. respectively. In England, outside London, the percentage of known homosexuals with early syphilis was 25-1, but reached 62-1 in the twenty participating clinics in the capital. In London four out of five of the homo- sexuals with syphilis were treated in but five clinics in the West End, where they comprised no less than 73-3 per cent. of infections compared with 37 2 per cent. in the other fifteen clinics. (Fig. 11). 80 FIG. 10 Diagram to show how a slight extra degree of promiscuity may cause a large increase in venereal disease Male homosexuality A noteworthy feature has been the much more frequently recognized association of early syphilis in males with homosexuality, particularly in the larger cities where homosexuals may be responsible for the bulk of infections. Although this would appear fundamentally to be a problem of the more permissive society and greater promiscuity amongst homosexuals, the observed increase is also due at least in part to the fact that such persons now feel freer to discuss their behaviour. Homosexuality involves about 4 per cent. of adult males and a moderately active homosexual man may have contact with 100 different males each year (Gebhard, 1971). 70 c .2_ tU60 u 0r- 20 20- 37.2 London 25.1 except England West 13.5 except End9.5 Scotland London I Wales 73.3 London West End FIG. 1 1 Percentage of homosexually acquired infections with primary and secondary syphilis in males A similar pattern was seen in gonococcal infections (Fig. 12); homosexuals represented 9-8 per cent. of the total and 27-6 per cent. in the five clinics in the o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://sti.b m j.co m / B r J V e n e r D is: first p u b lish e d a s 1 0 .1 1 3 6 /sti.5 0 .3 .1 6 9 o n 1 Ju n e 1 9 7 4 . D o w n lo a d e d fro m http://sti.bmj.com/ 176 British Journal of Venereal Diseases 30- 2- 20- 0 .0- 1 0 7.7 4.0 4.1 4.6 London I Wnl . IQntnlln9!.nt W.,t End 27.6 London West End 01 I Yvies la u w IL mdcp l -- I - FIG. 12 Percentage of homosexually acquired infections with gonorrhoea in males West End of London. However, as approximately forty times as much gonorrhoea as primary and secondary syphilis occurred in males, gonorrhoea represents the greater numerical problem (Fig. 13). EJ Heterosexual 0 Penile homosexual E Ano-rectal homosexual Syphilis Gonorrhoea F I G. 13 Relative importance of homosexual infections with syphilis and gonorrhoea in males It is difficult to explain why syphilis has lurked more commonly in the homosexual male than in the heterosexual female (where the chancre may also be concealed, e.g. on the cervix), unless it is agreed that greater promiscuity in terms of sexual partners over a period of time has occurred in homosexuals now that previously strong taboos have been removed from such behaviour in many countries. Oral sexual contact The influence of oral sex in relation to venereal disease has recently been highlighted by Bro- Jorgensen and Jensen (1971), who found gonococci in the throat of 6 per cent. of Danish men and 9 per cent. of Danish women, and by Hellgren (1971) who noted that fifty of 200 Swedish patients with uro- genital gonorrhoea admitted to oral sex at their last intercourse. Oral infections with syphilis remain relatively uncommon. Those which are found today are more likely to be associated with oral intercourse than with kissing, which was regarded as the usual method of contraction 25 years ago. It has been thought likely that, possibly following the greater dissemination of pornographic and near pornographic films, the practice of oral intercourse is increasing in Western Society. In a recent series of 105 female gonorrhoea contacts seen at St. Mary's, 41 0 per cent. admitted to oral sex with the partner or partners recently involved. (Rectal intercourse had also occurred in 18-1 per cent. of patients- Cornthwaite, Savage, and Willcox, 1974). But here again it must be noted that 20 years ago Kinsey, Pomeroy, Martin, and Gebhard (1953) found that, of younger females who had had some but not extensive coital experience, 16 per cent. had indulged in oral stimulation of the male genitalia as had 43 per cent. of those with more extensive experience. The latter figure (which reached 62 per cent. amongst the more educated) varied little from the 38 per cent. noted in those born before 1900. In view of the success of a recent film in the U.S.A., the report is awaited of the first case of a chancre at the lower end of the oesophagus! Other behavioural factors Other changes in the presentation of syphilis have been brought about by new industrial and other practices. No longer do oral chancres occur in glassblowers, although these were once not so uncommon (Royal Commission on Venereal Diseases, 1916). An interesting recent presentation is that of double chancre arising in the vasectomy scars of a patient who had cooperated in the Indian steriliza- tion programme and who had had a night 'on the town' shortly afterwards (Bai, 1973) (Fig. 14). Summary and conclusions (1) The evolutionary patterns of the treponematoses, occasioned by environmental circumstances, from pinta and yaws through endemic to venereal syphilis are outlined. A reversal from venereal to endemic syphilis may occur should social conditions deterio- rate. (2) Changes are still occurring today in the patterns of venereal syphilis, particularly as a result of the introduction of penicillin and of human behaviour. (3) The mode of action of penicillin and its effects in the various stages of syphilis are outlined. The significance of the treponemal forms found in cases of treated late disease is considered, but notwith- standing these the practical results obtained by penicillin treatment remain excellent. o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://sti.b m j.co m / B r J V e n e r D is: first p u b lish e d a s 1 0 .1 1 3 6 /sti.5 0 .3 .1 6 9 o n 1 Ju n e 1 9 7 4 . D o w n lo a d e d fro m http://sti.bmj.com/ Changing patterns of treponemal disease 177 F I G. 14 Chancres arising in vasectomy scars (Courtesy of Bai, 1973) (4) In developed countries today, syphilis is ap- parently becoming a milder disease with fewer exuberant lesions, a low incidence of previously common secondary relapses and gummata, and a much reduced incidence of other late manifestations. On the other hand, re-infections and ano-rectal infections have become more common. For this a number of factors are responsible, including better nutrition, better hygiene, and above all the discovery of penicillin, treatment with which would be expected to tend towards the removal of the more virulent strains leaving the more insidious. (5) Behavioural patterns have also contributed, especially in relation to ano-rectal infections. Data concerning homosexual infections and oral inter- course are presented. (6) Doubtless, as long as human behaviour changes and the environment evolves, these alterations will be reflected also in the patterns of treponemal disease. References BAI, K. V. (1973) Personal comnmunication BASSET, A., and BOIRON, H. (1965) Bull. Mem. Fac. mixte Mid. Pharm. (Dakar), 13, 308 BELL, C. 0. (1971) Personal communication BRITISH COOPERATIVE CLINICAL GROUP (1973) Brit. J7. vener. Dis., 49, 329 BRO-J0RGENSEN, A., and JENSEN, T. (1971) Brit. med. J7., 4, 660 COCKBURN, T. A. (1961) Bull. Wld Hlth Org., 24, 221 COLLART, P., BOREL, L.-J., and DUREL, P. (1962) Ann. Inst. Pasteur, 102, 596 , FRANCESCHINI, P., and DUREL, P. (1971) Brit. J. vener. Dis., 47, 389 CORNTHWAITE, S. A., SAVAGE, W. D., and WILLCOX, R. R. (1974) Brit. J. clin. Pract. in press CSONKA, G. W. (1952) Med. Illustr., 6, 401 Du TOIT, J. A. (1969) S. Afr. med. 7., 43, 355 EISENBERG, H., PLOTKE, F., and BAKER, A. H. (1949) J. vener. Dis. Inform., 30, 7 FEJER, E. (1948) Orv. Lapja, 4, 616 FRIBOURG-BLANC, A., NIEL, G., and MOLLARET, H. H. (1963) Bull. Soc. Path. exot., 56, 474 GEBHARD, P. H. (1971) In 'The VD Crisis', pp. 60-62. Amer. Soc. Hlth Ass. and Pfizer Laboratories, N.Y. GJESTLAND, T. (1955) Acta derm.-venereol. (Stockh.), 35, Suppl. 34 GRIN, E. I (1953) 'Epidemiology and Control of Endemic Syphilis'. WHO Molograph Series No. 11, W.H.O., Geneva - and GUTHE, T. (1973) Brit. J7. vener. Dis., 49, 1 GUTHE, T., and LUGER, A. (1957) Dermatologica (Basel), 115, 248 -- RIDET, J., VORST, F., D'COSTA, J., and GRAB, B. (1972) Bull. Wld Hlth Org., 46, 1 and WILLCOX, R. R. (1954) Chron. Wld Hlth Org., Special Number 8, p. 33 - - (1971) J. roy. Soc. Hlth, 91, 122 HACKETT, C. J. (1957) J. trop. Med. Hyg., 29, 7 - (1963) Bull. Wld Hlth Org., 29, 7 HELLGREN, L. (1971) Lakartidningen, 68, 569 HERREJON, S. G. (1938) 'El Mal Del Pinto' Revista de Informacion Terapeutica Leverkusen (Alemania) HUDSON, E. H. (1928) U.S. naval med. Bull., 26, 817 (1963) Amer. J. med. Sci., 246, 645 (1964) Brit. J3. vener. Dis., 40, 43 (1965) Amer. Anthropol., 67, 885 IDS0E, I., GUTHE, T., and WILLCOX, R. R. (1972) Bull. Wld Hlth Org., 47, Suppl. 'Pencillin in the Treatment of Syphilis' KERN, A. (1972) Medicamentum, No. 25, p. 6 KINSEY, A. C., POMEROY, W. B., MARTIN, C. E., and GE}B- HARD, P. H. (1953) 'Sexual Behaviour in the Human Female'. Saunders. Philadelphia KIRALY, K., and CAUSSE, G. (1973) Tribuna Medica, Madrid, No. 484, p. 16 o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://sti.b m j.co m / B r J V e n e r D is: first p u b lish e d a s 1 0 .1 1 3 6 /sti.5 0 .3 .1 6 9 o n 1 Ju n e 1 9 7 4 . D o w n lo a d e d fro m http://sti.bmj.com/ 178 British Journal of Venereal Diseases KUHN, U. S. G., MEDINA, R., COHEN, P. G., and VEGAS, M. (1970) Brit. J. vener. Dis., 46, 311 LANCEREUX, E. (1868) 'A Treatise on Syphilis', vol. 1. New Sydenham Society, London LUGER, A. (1972) Brit. J. vener. Dis., 48, 356 (1973) WHO Document VDT/RES/73. 297 MEDINA, R. (1967) Dermatologia Ibero Latino Amer., Eng. Ed., vol. 121 MURRAY, J. F., MERRIWEATHER, A. M., FREIDMAN, M. L., and DE VILLIERS, D. J. (1956) Bull. Wld Hlth Org., 15, 975 MURRELL, M., and GRAY, M. S. (1947) Brit. med. J., 2, 206 OVtINNIKOV, N. M., and DELEKTORSKIJ, V. V. (1971) Brit. J. vener. Dis., 47, 315 PELZER, H. (1967) In 'Molekularbiologie', ed. T. Wieland and G. Pfleiderer. Umschau-Verlag, Frankfurt on Main RAJAM, R. V., and RANGIAH, F. N. (1952) WHO Working Document, VDT 79 REES, E. (1954) Brit. J. vener. Dis., 30, 19 REIN, C. R., KITCHEN, D. K., MARQUEZ, F., and VARELA, G. (1952) J. invest. Derm., 18, 137 RHODES, F., and ANDERSON, S. E. (1970) Papua and New Guinea med. J., 13, 49 ROYAL COMMISSION ON VENEREAL DISEASES (1916) 'Final Report ofthe Commissioners'. H.M. Stationery Office, London SCHAMBERG, I. L. (1963) Brit. J. vener. Dis., 39, 87 SMITH, J. LAWTON, DAVID, N. J., INDGIN, S., ISRAEL, C. W., LEVINE, B. M., JUSTICE, J., McCRARY, J. A., SCHATZ, N. J., SPITZER, M. L., SPITZER, W. O., and WALTER, E. K. (1971) Ibid., 47, 226 - and ISRAEL, C. W. (1967) J. Amer. med. Ass., 199, 980 TAYLOR, W. N. (1954) S. Afr. med. J., 28, 176 TURNER, T. B., HARDY, P. H., and NEWMAN, B. (1969) Brit. J. vener. Dis., 45, 183 VAN DER SLUIS, I. (1969) 'The Treponematosis of Tahiti, its Origin and Evolution. A Study of the Sources'. Amsterdam B.M., Israel, N.V. VELDKAMP, H. (1960) Antonie van Leeuwenhoek, 26, 103 WILLCOX, R. R. (1951a) Lancet, 1, 558 (1951b) S. Afr. med. J., 25, 501 (1953) 'Progress in Venereology', p. 171. Heinemann, London (1960) Brit. J. vener. Dis., 36, 78 - (1972) Trans. St. John's Hosp. derm. Soc., 58, 21 (1973) Sandorama, No. 1, 4-8 WORLD HEALTH ORGANIZATION (1972) 'The Inter- country Spread of Venereal Diseases', Report on a Working Group, Copenhagen, 7-10 December 1971. Regional Office for Europe, Copenhagen YOBs, A. R., CLARK, J. W., MOTHERSHED, S. E., BULLARD, J. C., and ARTLEY, C. W. (1968) Brit. J. vener. Dis., 44, 116 Modifications des aspects des tr6pon6matoses SOMMAIRE (1) On decrit 1'evolution des aspects des treponematoses due aux circonstances de 1'environnement, menant de la pinta et du pian a la syphilis v6n6rienne en passant par la syphilis endemique. De venerienne, la syphilis peut prendre le type endemique si les conditions sociales se deteriorent. (2) Les aspects se modifient aujourd'hui encore pour la syphilis venerienne, ceci resultant particulierement de l'introduction de la penicilline et du comportement humain. (3) On examine le mode d'action de la penicilline et ses effets aux divers stades de la syphilis. On examine la signification des formes treponemiques trouvees dans des cas traites tardivement mais, quoi qu'il en soit, les resultats pratiques obtenus par le traitement par la penicilline restent excellents. (4) De nos jours, dans les pays developpes, la syphilis parait devenir plus benigne, avec moins de lesions exuberantes, une faible incidence des reprises secondaires et des gommes, faits communs anterieurement, et une forte diminution de l'incidence des autres manifestations tardives. Par contre, les reinfections et les atteintes ano- rectales sont devenues plus frequentes. Un certain nombre de facteurs en sont responsables, dont une meilleure nutrition, une meilleure hygiene et, par dessus tout, la decouverte de la p6nicilline, traitement dont on peut penser qu'il tend a supprimer les souches les plus virulentes, laissant subsister les souches les plus insidi- euses. (5) Les types de comportement ont aussi joue un role, specialement en ce qui concerne les infections ano- rectales. On presente des informations sur les infections homosexuelles et celles dues aux rapports oraux. (6) I1 n'est pas douteux qu'aussi longtemps que le comportement humain changera et que l'environnement evoluera, ceci influencera les aspects de la maladie treponemique. o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://sti.b m j.co m / B r J V e n e r D is: first p u b lish e d a s 1 0 .1 1 3 6 /sti.5 0 .3 .1 6 9 o n 1 Ju n e 1 9 7 4 . D o w n lo a d e d fro m http://sti.bmj.com/ work_74hlkir2vbezfelaytu37ejiki ---- 1430003 1..14 UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl) UvA-DARE (Digital Academic Repository) Citation analysis of the scientific publications of Britton Chance in ISI citation indexes Li, L.Z.; Leydesdorff, L.; Nioka, S.; Sun, N.; Garfield, E. DOI 10.1142/S1793545814300031 Publication date 2014 Document Version Final published version Published in Journal of Innovative Optical Health Sciences Link to publication Citation for published version (APA): Li, L. Z., Leydesdorff, L., Nioka, S., Sun, N., & Garfield, E. (2014). Citation analysis of the scientific publications of Britton Chance in ISI citation indexes. Journal of Innovative Optical Health Sciences, 7(2), 1430003. https://doi.org/10.1142/S1793545814300031 General rights It is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons). Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: https://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. Download date:06 Apr 2021 https://doi.org/10.1142/S1793545814300031 https://dare.uva.nl/personal/pure/en/publications/citation-analysis-of-the-scientific-publications-of-britton-chance-in-isi-citation-indexes(bf03b40b-d2f1-4484-b3a0-fe942b73c1f3).html https://doi.org/10.1142/S1793545814300031 Citation analysis of the scienti¯c publications of Britton Chance in ISI citation indexes Lin Z. Li*,†,||, Loet Leydesdor®‡, Shoko Nioka†, Nannan Sun*,†, § and Eugene Gar¯eld¶ *Department of Radiology, Perelman School of Medicine University of Pennsylvania, Philadelphia, PA 19104, USA †Britton Chance Laboratory of Redox Imaging, Johnson Research Foundation Department of Biochemistry and Biophysics, Perelman School of Medicine University of Pennsylvania, Philadelphia, PA 19104, USA ‡University of Amsterdam Amsterdam School of Communications Research (ASCoR), Netherlands § Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Wuhan 430074, P. R. China ¶Institute for Scienti¯c Information — Thomson Reuters Philadelphia, PA 19130, USA ||linli@mail.med.upenn.edu Received 4 March 2014 Accepted 4 March 2014 Published 2 April 2014 Britton Chance was a pioneer in many scienti¯c ¯elds such as enzymatic reaction kinetics, bioenergetics, metabolism, in vivo NMR, and biophotonics. As an engineer, physical chemist, physicist, physiologist, biophysicist, biochemist, innovator and educator, he had worked in diversi¯ed ¯elds over extended periods between 1926 until his death in 2010, at the age of 97. In order to illustrate his scienti¯c career and great impact on research from a new perspective, we employ scientometric analysis tools to analyze the publications of Britton Chance with data downloaded from the ISI Citation Indexes in April 2013. We included articles, reviews and proceeding papers but excluded meeting abstracts. In total, we obtained 1023 publication records with 1236 authors in 266 journals with 17,114 citations from 1945 to 2013. We show the annual publications and citations that Britton Chance received from 1945 to 2013, and generate HistCite maps on the basis of the global citations (GCS) and local (self) citations (LCS) to show the citation relationships among the top-30 publications of Britton Chance. Metabolism and the This is an Open Access article published by World Scienti¯c Publishing Company. It is distributed under the terms of the Creative Commons Attribution 3.0 (CC-BY) License. Further distribution of this work is permitted, provided the original work is properly cited. Journal of Innovative Optical Health Sciences Vol. 7, No. 2 (2014) 1430003 (14 pages) #.c The Authors DOI: 10.1142/S1793545814300031 1430003-1 J. I nn ov . O pt . H ea lt h S ci . 2 01 4. 07 . D ow nl oa de d fr om w w w .w or ld sc ie nt if ic .c om by U N IV E R S IT Y O F A M S T E R D A M o n 12 /1 6/ 14 . F or p er so na l us e on ly . http://dx.doi.org/10.1142/S1793545814300031 development of physical methods to probe it appear to be the connecting thread of the lifelong research of Britton Chance. Furthermore, we generate the journal map and co-authorship map to show the broad scope of research topics and collaborators and the high impacts of the scienti¯c oeuvre of Britton Chance ranging from physics, engineering, chemistry and biology to medicine. Keywords: Scientometric analysis; impact; HistCite; citation tree; metabolism; mitochondria. 1. Introduction to Britton Chance Britton Chance (1913–2010), one of the most out- standing scientists in the world in the 20th century, had been a legendary ¯gure in the history of science. He was famous for his enthusiasm in sailing due to his family tradition, which brought him the rare experience of catching a big, over 400 lb blue marlin in Caribbean Sea, an Olympic Gold Medal for 5.5 m boat sailing in 1952, and a couple of world cham- pionships of sailing in 1960s. However, his talent, enthusiasm and fame were far more distinguished in science. As a teenager, he invented an optoelectric device for ship autosteering, which was later tested satisfactorily for large commercial ships such as the Texas Sun and New England Star in 1930s. Along with these testing trips, he was admitted to the Trinity College of Cambridge University in late 1930s under the mentorship of Glenn Millikan, the son of the Nobel Laureate Robert A. Millikan, who measured the charge of the electron. Eventually, he graduated with two PhDs, one in Physical Chem- istry from the University of Pennsylvania in 1940, and one in Physiology from the University of Cambridge in 1942. His PhD thesis was on devel- oping a fast mini stop-°ow device for measuring the kinetics of enzymatic reactions. With such a device, he achieved the ¯rst experimental, quantitative demonstration of the existence of Michaelis-Menten enzyme–substrate complex in early 1940s. He was also highly skillful with circuits and electronics. From 1941–1946, he was recruited to the Radiation Lab in MIT for developing advanced radar systems including anti-aircraft radar SCR584 and airborne radar bomber sight used for ¯ghting against Nazi during World War II. He quickly rose to be a member of Steering Committee of the Radiation Lab, leading a large group of physicists with over 200 people. His group taught Presper Eckert how to make key circuits and overcome some technical problems for ENIAC, the world 1st general purpose electronic digital computer at the University of Pennsylvania in 1946. From 1940s till 2010 except a couple of short term leaves, he stayed in the Johnson Research Foundation, Department of Biochemistry and Biophysics at the University of Pennsylvania for seven decades. From 2006 to 2010, he spent half a year annually in research institutions in Asian countries and regions such as Singapore, Mainland China and Taiwan to conduct research and education, helping the development of biopho- tonics in those places. His eight decades of scienti¯c research (1926– 2010) culminated into numerous scienti¯c dis- coveries and technological inventions. He had advanced many frontier research ¯elds at the time with both the development of new methods/devices and their applications to key biological questions. Apart from the aforementioned enzyme kinetics studies with his mini stop-°ow device, in 1950s, Chance invented the dual-wavelength spectropho- tometer which has been widely used for studying turbid biological samples around the world until today. He applied this instrument to extensive in- vestigations on the electron transport in mitochon- drial respiration, redox cofactors and metabolic control mechanisms. In 1960s, he ¯rst discovered the electronic tunneling process in biological sys- tems. In 1970s, he identi¯ed hydrogen peroxide released by the respiratory chain in mitochondria. From 1970s to early 1980s, he developed the 3D cryogenic redox scanner for imaging tissue redox state and its heterogeneity at submillimeter resol- ution. In the 1970–1980s, he was also a key player in developing in vivo31 P-NMR spectroscopy for bioe- nergetics studies and using X-ray spectroscopy to elucidate the structure–function relation of biomo- lecules. Since late 1980s, Prof Chance and his col- laborators had founded the ¯eld of biophotonics by developing in vivo NIR spectroscopy and imaging methods, mainly based on hemoglobin absorption, time-resolved spectroscopy, photon di®usion, etc. These methods have been widely applied in both laboratory and clinic studies for the measurement of blood oxygenation, volume, and °ow, brain activi- ties, muscle functions and cancer detections and diagnosis. The new research directions he developed L. Z. Li et al. 1430003-2 J. I nn ov . O pt . H ea lt h S ci . 2 01 4. 07 . D ow nl oa de d fr om w w w .w or ld sc ie nt if ic .c om by U N IV E R S IT Y O F A M S T E R D A M o n 12 /1 6/ 14 . F or p er so na l us e on ly . during the last decade of his life includes developing novel molecular beacons for cancer diagnosis and therapy, predicting cancer aggressiveness by redox scanning, and developing an oral optical metabol- ometer to detect nutritional status in human sub- jects. The latter two directions completed the circle of his scienti¯c research since 1950s by utilizing intrinsic optical signals from mitochondria. Among many honors and awards1 he has received are the memberships of national academies of sci- ences from six countries including United States, Italy, United Kingdom, Sweden, Germany and Argentina; over 10 honorary PhD and MD degrees; US National Medal of Sciences (1974); The Gold Medal for Distinguished Service to Medicine, College of Physicians, USA (1987); The Gold Medal of the Society of Magnetic Resonance in Medicine, USA (1988); The Benjamin Franklin Medal for Dis- tinguished Achievement in the Sciences, American Philosophical Society (1990); The Christopher Columbus Discovery Award in Biomedical Research, National Institutes of Health, USA (1992); The In- ternational Society for Optical Engineering (SPIE) Lifetime Achievement Award (2005); The Gold Medal of American Roentgen Ray Society (2006); Distinguished Achievement Award of American Aging Association (2006). Due to his tireless e®ort in promoting scienti¯c exchange and collaboration between the East and the West, Chance received the Friendship Award from the State Administration of Foreign Experts A®airs of China in 2008. He was further recognized in 2009 with the International Science and Technology Cooperation Award, which is China's highest national honor given to foreign scientists. In 2013, Chance was inducted into the Innovators Walk of Fame at the University City Science Center, Philadelphia. 2. Scientometric Analysis To commemorate a great scholar and carry on his/ her legacy to future generations, scientometric analysis can be used in addition to anecdotal stories. Scientometric analyses have been utilized to evalu- ate the achievements of scholars,2 and usually these scholars have a focus within a speci¯c ¯eld. Here we employed several tools to evaluate the scienti¯c contribution of Britton Chance whose career span- ning multiple disciplines. Our analysis was based on a dataset downloaded from the ISI Citation Indexes in April, 2013. Articles, reviews and proceeding papers were included with no meeting abstracts. We obtained 1023 publication records in total from 1945 to 2013 including 1236 authors in 266 journals with 17,114 citations. Publication periods. We try to correlate the annual publication pro¯le of Chance with his research activities. In these 67 years between 1945 and 2012 (age 32–97), average of 15.3 papers were published with 255 citations annually. Note that these numbers underestimate his published manu- scripts, because many of his manuscripts were published in places not indexed by ISI Citation Indexes yet. His publications during his graduate studies were not covered by ISI. Moreover, during the time before World War II ended in 1945, he worked in the area of electronic engineering in a secret mission at Radiation Laboratory, thus, most of his works were not published in academic journals. Figure 1 shows the annual number of published manuscripts from 1945–2012. At a glance, there are seven periods of Gaussian distributions over the whole time, and each one seems to represent roughly main subjects of his works. The publi- cations of these periods went up and down, and we found that, for quite a few occasions, the publi- cations of new ideas changed the research direction of Chance and boosted his publication records. The ¯rst Gaussian period (1945–1956, peak at 1952) includes a number of applications of the micro stop-°ow method to enzyme–substrate kinetics3–5 and the development of dual beam spectrometer6 enabling the study of turbid biological samples. With those apparatuses, Chance was active himself in several areas as well as he helped many other research works in various ¯elds of physiology, chemistry, biochemistry, enzymology, etc. In 1947, Chance was the ¯rst to identify catalase compound I as an intermediate in the reaction of hydrogen peroxide and catalase.7 In 1955, he published a landmark paper series with G.R. Williams on res- piratory enzymes in oxidative phosphorylation.8–11 Chance ¯nally set his life work into the mitochon- drial biochemistry. The second period (1957–1968) contains a peak at 1959 with the key publications of Chance's life- long work on metabolic control mechanisms.12–17 The function of mitochondrial energy metabolism was well understood by the kinetic experiments of substrate and products relationships using the Citation analysis of the scienti¯c publications of Britton Chance 1430003-3 J. I nn ov . O pt . H ea lt h S ci . 2 01 4. 07 . D ow nl oa de d fr om w w w .w or ld sc ie nt if ic .c om by U N IV E R S IT Y O F A M S T E R D A M o n 12 /1 6/ 14 . F or p er so na l us e on ly . double beam spectrometer. The peak at 1959 also came after the ¯rst observation of mitochondrial NADH °uorescence18 by him and Baltsche®sky in 1958 and coincided with the ¯rst observation of tissue NADH °uorescence19 by Chance and Jobsis in 1959. Chance et al. published in 1962 the ¯rst in vivo observation of NAD(P)H °uorescence and redox state from the brain and kidney.20–22 As we can see with his work on NADH °uorescence, Chance started with mitochondria followed by tis- sue and in vivo studies. This group of papers laid down a milestone for bioenergetics research and Chance's later work on the translational and clinical studies. From 1962–1968, Chance continued mito- chondrial bioenergetics research on Complex I to IV with optical spectrometers and °uorometers of cytochromes and NADH. His publication peaked again in 1966 coinciding with another landmark discovery by him and DeVoult on the ¯rst exper- imental observation of quantum mechanical electron tunneling in biological system.23 The importance of this work was recognized later on by a conference of the Royal Society on quantum catalysis in enzymes in 2005.24 During the valley of 1967–1968, Chance and coworkers identi¯ed oxidized °avoproteins (Fp including FAD) as another source of intrinsic °uor- escence from mitochondria,25–27 which contributed to another rebound of publications in the following years. The 3rd broad period of Chance publication curve from 1969–1977 appears to have the 2nd largest publication peak with studies ranging from NADH, °avoproteins, cytochoromes, calcium uptake to hydrogen peroxide generation. The use of oxidized °avoproteins together with NADH makes the in vivo measurement of redox status (Fp/NADH or Fp/ (FpþNADH)) possible by the °uorescence spec- troscopy and imaging. Therefore Chance et al. developed this idea and technologies into transla- tional researches by inventing NADH °uorometery, °ying spot technology and cryogenic NADH/Fp redox scanning, etc. Still now, these are the only °uorescence signals used clinically, mainly for can- cer detection. Chance wrote in his unpublished autobiography regarding the importance of his dis- covery of the °uorescence of NADH and Fp from mitochondria both in vivo and ex vivo: \. . .This was perhaps the most important discovery of my career because, for the ¯rst time, we could obtain optical signals from living mitochondrial tissues. A series of papers, exploring this discovery in the liver, kidney, adrenal gland, and brain, opened a new ¯eld of metabolic research. . .." Indeed, since 1950s Chance kept publishing on NADH and Fig. 1. The annual number of publications of Britton Chance from 1945–2012. Graph reproduced from ISI Citation Indexes (accessed in April, 2013 excluding meeting abstracts) with modi¯cations. There were seven periods I–VII as described in the text. L. Z. Li et al. 1430003-4 J. I nn ov . O pt . H ea lt h S ci . 2 01 4. 07 . D ow nl oa de d fr om w w w .w or ld sc ie nt if ic .c om by U N IV E R S IT Y O F A M S T E R D A M o n 12 /1 6/ 14 . F or p er so na l us e on ly . °avoproteins throughout the rest of his life. The work on NADH and °avoproteins, along with his other research work including the studies on cyto- chromes,28–30 discovery of the calcium uptake by mitochondria and its e®ects on bioenergetics,31 discovery of hydrogen peroxide generation by mitochondria,32 etc., really drove the publication of Chance onto a new level in the subsequent years until late 1970s, with about 20 papers annually. The 4th period in 1978–1981 is only 4 years, and it is the beginning of three important new directions of publications. The ¯rst direction of new publi- cations marked the beginning of Chance's e®ort in developing 31P-NMR techniques for bioenergetics studies in organs and human body.33–36 Chance funded himself to make an NMR machine for studying phosphorous energetics in human subjects including his own leg in vivo.33,37 The second new direction of publications was about the chemilumi- nescence38–40 emitted by the lipid peroxidation process in biological systems, which was the con- tinuation of the interest of Chance on metabolism, redox reactions and free radicals. Chance published his studies on chemiluminescence from late 1970s to mid 1990s. He and coworkers probably provided one of the early experimental evidences for the generation of singlet oxygen in biological pro- cesses.41–43 The third source of new publications was the studies44–48 by Chance and Power et al. using synchrotron radiation X-ray spectroscopy to illustrate structure–function relation for biomole- cules including cytochrome oxidase, myoglobin, glyoxalase, etc. The 5th period of Chance publication (1982– 1989) has the highest peak in 1987 with an annual publication of 32 papers. That was on average two papers per three week at the age of 74. That was the period when Chance and Leigh et al. had made signi¯cant progress in developing in vivo NMR for bioenergetics and applying it to diseases. From 1984 to 1987, every year Chance and Leigh coauthored 10–15 papers according to the ISI Science Citation indexes. Other sources of contributions include the chemiluminescence studies and the synchrotron radiation studies aforementioned. After the peak in 1987, Chance publication lowered to 15 in 1990. In 1988, Chance and Leigh et al. initiated time- resolved measurements on hemoglobin and myo- globin in tissues.49,50 Chance then published with M. S. Patterson and B. C. Wilson the work on time- resolved optical spectroscopy,51 which made it possible to measure scattering and absorption coe±cients in biological tissue. This paper was revolutionary for optical ¯elds because it gave birth to the di®usive biomedical photonics. The last two Gaussian periods of Chance publi- cation (1990–1999 and 2000–2010) are truly optical and more translational periods of Chance's work. Chance, as a founding father of modern biopho- tonics, had collaborated with A. Yodh and a num- ber of researchers since 1990s to develop NIR spectroscopy and imaging, including time resolved spectroscopy, photon di®usion tomography (PDT), phased array and their biomedical applications to study brain (fNIR), muscle and various diseases such as breast cancer.52–63 Chance et al. also inte- grated NIR spectroscopy/imaging with magnetic resonance imaging.58,64 Since 2002, Chance had publications with Zheng and Glickson et al. on molecular beacons, nanoparticles and photo- dynamic therapy.65–69 His publication rebounded in 1991 and maintained an average publication of about 18 papers annually for 15 years until 2005. In 2006, Chance ran out of his research funding and since then he was invited to teach and conduct research in Singapore, Mainland China and Taiwan half of the time each year, while Li and Xu were maintaining his redox scanning lab at the Univer- sity of Pennsylvania. His publication went down but was still maintained at about eight papers on average per year until 2010. During this period of time, he and his coworkers investigated on the development of optical imaging biomarkers for cancer diagnosis and tumor metastatic poten- tial,70–73 stem cell stemness74 and a metabol- ometer75 for monitoring human nutritional status. Chance worked on research till the last few days of his life. Li et al. remembered discussing research data with him in the hospital room three days before his passing away. Citation trends. The annual citations of the Chance publications shown in Fig. 2 exhibited 4 rising (R) phases and 2 leveling (L) phases. The 1st rising phase (R1) from 1947 till 1958, increasing with about 20 citations per year, is presumably based on his studies on enzyme kinetics and pio- neering work on oxidative phosphorylation. The phase R2 from 1959 to 1972 has the steepest slope (� 60 citations per year) among the four R phases, indicating his scienti¯c in°uence expanded at the fastest pace during these years. This expansion of fame should be signi¯cantly contributed by his Citation analysis of the scienti¯c publications of Britton Chance 1430003-5 J. I nn ov . O pt . H ea lt h S ci . 2 01 4. 07 . D ow nl oa de d fr om w w w .w or ld sc ie nt if ic .c om by U N IV E R S IT Y O F A M S T E R D A M o n 12 /1 6/ 14 . F or p er so na l us e on ly . previous work on the stop-°ow measurement of enzyme–substrate kinetics. Indeed, \when Manfred Eigen won the [Nobel] prize in 1967 for his tem- perature jump method that could dissect chemical reactions even more ¯nely than Brit's stopped °ow approach, he publicly regretted not being able to share the honor with Britton Chance" (Gottfried Schatz, 2011 http://www.med.upenn.edu/biocbiop/ chance/symposium/schatz/schatz talk.html). For Britton Chance, this was also a period with im- portant new discoveries that were nothing short of importance compared to his ¯rst experimental demonstration of the existence of Michaelis-Menten enzyme–substrate complex. He and his coworkers developed the dual-beam spectrometer for biological studies and characterized theelectron-transport chain and bioenergetic process in mitochondrial oxidative phosphorylation. They discovered the °uorescence of NADH and °avoproteins from mitochondria and translated these methods to tissue in vivo with many clinical applications. They also discovered the electron-tunneling in biological systems, and ident- i¯ed the calcium uptake and hydrogen peroxide generation by mitochondria. In 1974, Britton Chance was awarded the US National Medal of Sciences. The ¯rst leveling phase L1 corresponds to 1973–1976. The third rising R3 phase from 1976 to 1996 includes the original development of phos- phorous NMR and di®usive optical spectroscopy and imaging methods, with a slope similar to that of ¯rst phase, followed by the leveling phase L2 from 1997–2001 with over 1500 citations per year on average. The rising phase R4 is from 2002 to 2012 with a slope of 30 citations per year higher than that of R1 and R3. HistCite analysis. Figures 3 and 4 show the citation analysis results from HistCiteTM for top 30 papers with the highest global citations and local citations, respectively. The local citations refer to the citations only by the papers published by Chance himself. The citation relationships among these papers are displayed in these two ¯gures. The detailed paper information and the number of citations are also listed in the order of publication years from the oldest to the latest. For global citation analysis, there are six papers cited by over 1000 times. The No. 1 highest cited paper76 is a review by Chance et al. in 1979 on hydrogen peroxide metabolism in mammalian organs, with nearly 4000 citations. The fourth highest cited paper77 is also about hydrogen per- oxide, i.e., its generation by mitochondria, general Fig. 2. The annual citations of publications of Britton Chance from 1947–2013. Graph reproduced from ISI Citation Indexes (accessed in April, 2013 excluding meeting abstracts) with modi¯cations. R: rising phase; L: leveling phase as described in the text. L. Z. Li et al. 1430003-6 J. I nn ov . O pt . H ea lt h S ci . 2 01 4. 07 . D ow nl oa de d fr om w w w .w or ld sc ie nt if ic .c om by U N IV E R S IT Y O F A M S T E R D A M o n 12 /1 6/ 14 . F or p er so na l us e on ly . F ig . 3 . C it a ti o n tr ee a n d ta b le fr o m th e g lo b a l ci ta ti o n a n a ly si s o n th e p u b li ca ti o n s o f B ri tt o n C h a n ce b y H is tC it e. T h e a rr o w fr o m A to B in d ic a te s A ci ti n g B . Citation analysis of the scienti¯c publications of Britton Chance 1430003-7 J. I nn ov . O pt . H ea lt h S ci . 2 01 4. 07 . D ow nl oa de d fr om w w w .w or ld sc ie nt if ic .c om by U N IV E R S IT Y O F A M S T E R D A M o n 12 /1 6/ 14 . F or p er so na l us e on ly . F ig . 4 . C it a ti o n tr ee a n d ta b le fr o m th e lo ca l ci ta ti o n a n a ly si s o n th e p u b li ca ti o n s o f B ri tt o n C h a n ce b y H is tC it e. T h e a rr o w fr o m A to B in d ic a te s A ci ti n g B . L. Z. Li et al. 1430003-8 J. I nn ov . O pt . H ea lt h S ci . 2 01 4. 07 . D ow nl oa de d fr om w w w .w or ld sc ie nt if ic .c om by U N IV E R S IT Y O F A M S T E R D A M o n 12 /1 6/ 14 . F or p er so na l us e on ly . Fig. 5. Journal maps of Britton Chance publications. The size of sphere is proportional to number of publications. Fig. 6. Top journals with most publications from Britton Chance. Citation analysis of the scienti¯c publications of Britton Chance 1430003-9 J. I nn ov . O pt . H ea lt h S ci . 2 01 4. 07 . D ow nl oa de d fr om w w w .w or ld sc ie nt if ic .c om by U N IV E R S IT Y O F A M S T E R D A M o n 12 /1 6/ 14 . F or p er so na l us e on ly . properties and e®ects. The second78 and ¯fth8 highest cited papers are both about mitochondrial respirat- ory chain and oxidative phosphorylation. The third highest cited paper79 is about assays of catalases and peroxidases. The sixth highest cited paper51 is about the time-resolved optical spectroscopy marking the beginning of photon-di®usion spec- troscopy and imaging. Among the top 30 globally most cited papers, 4 are about enzyme assay and kinetic studies, 1 about dual beam spectrometer, 13 about mitochondrial oxidative phosphorylation, 5 about NIR imaging and spectroscopy (biophotonics), 1 about in vivo 31P-NMR, 1 about electron tunneling, 1 about calcium ion uptake by mitochondrion, 5 about hydrogen peroxide. For local citation analysis, three of the top six highest globally cited papers remain in the top six. They are two papers on respiratory chain/oxidative phosphorylation8,78 and one on time-resolved opti- cal spectroscopy.51 The other three ranked within Fig. 7. Coauthor maps. All coauthors with more than 1 publication with Britton Chance. The size of sphere is proportional to the number of papers. L. Z. Li et al. 1430003-10 J. I nn ov . O pt . H ea lt h S ci . 2 01 4. 07 . D ow nl oa de d fr om w w w .w or ld sc ie nt if ic .c om by U N IV E R S IT Y O F A M S T E R D A M o n 12 /1 6/ 14 . F or p er so na l us e on ly . the top six locally cited are all on respiratory chain/ oxidative phosphorylation.10,80,81 Among the top 30 locally most cited papers, 4 papers are about enzyme assay and kinetic studies, 1 about dual beam spec- trometer, 16 about mitochondrial respiration and redox state, 1 about calcium ion uptake by mito- chondrion, 5 about NIR imaging and spectroscopy (biophotonics), 4 about in vivo 31P-NMR. It appears that the studies on mitochondrial metabolism and the related development of optical techniques are most-often cited by Chance himself. From the LCS map (Fig. 4) we can see that these work form the center of the citation tree, with biophotonics and NMR bioenergetics as side lobes linked to the center. This relationship indicates mitochondrial metab- olism as a central basis of Chance research rationale and a long-term pursued research goal. During the last 20 years of his life, Chance appeared to have diversi¯ed his research and moved away from this research focus by developing new techniques such as in vivo NIR spectroscopy and imaging. Nevertheless, these new methods, although with many novel ap- plications beyond mitochondrial metabolism, are important for probing and understanding about tis- sue metabolism. Diversity of research ¯elds and collaborators. Figure 5 shows the journal maps of Chance publi- cations. The size of sphere is proportional to the logarithm of the number of publications. Among the 266 journals, Chance has published in this ISI database, the leading journals include Journal of Biological Chemistry, Proceedings of National Academy of Sciences (PNAS), Nature, Review of Scienti¯c Instrumentation, Journal Biomedical Optics, Science, Journal of Applied Physiology, Analytical Biochemistry, New England Journal of Medicine, Physics in Medicine and Biology, Brain Research, Medicine & Science in Sports & Exercise, NMR in Biomedicine, and so on. From these journal titles (only a portion of journal titles shown in Fig. 5), we can see that the research of Chance covered multiple disciplines ranging from physics, engineering, biology to medicine. Figure 6 provides more detailed information about the top 19 journals with most publications from Chance. Impressively there are 92 papers in Journal of Biological Chem- istry, 37 in PNAS, 27 in Nature and 16 in Science. Figure 7 is the coauthor map showing all coauthors with more than 1 publication with Chance. The size of sphere is proportional to the number of papers. We can see S. Nioka, J. S. Leigh, A. Yodh as the top 3 coauthors with the most coauthored papers with Britton Chance. 3. Discussion and Summary Note that all the above analysis and discussion are based on the 1023 records collected by ISI citation database in April, 2013. Our own collection of Brit- ton Chance's publication record, which is still an ongoing process, showed over 1500 manuscripts. We may perform additional analysis on this database once it is complete. This may provide a more com- plete picture about his research activity. Further- more, considering the tremendously diversi¯ed multi-disciplinary research conducted by Britton Chance, we can only cover some major research topics we are familiar with. The scientometric methods we used have a limited number of angles of perspectives. It is highly possible we fail to disclose many interesting or meaningful connections among the research publications by Chance and his research activities. In summary, we have presented the ¯rst scien- tometric analysis on a world preeminent scholar Britton Chance, whose research spanned multiple disciplines from physics, engineering, biology to medicine. We try to understand the pro¯les of his annual publications and citations by correlating them with his research activities. We have also summarized some key research areas that Britton Chance had focused and exerted great impact on. Among the diversi¯ed research studies Chance had conducted, metabolism and the development of physical methods to probe it appeared to be the central thread that connected all the dots. We also note that Chance had many excellent collaborators from very diversi¯ed ¯elds of science throughout his life, and that had enabled him to make such a great amount of publications with tremendous impact on science. References 1. L. Z. Li, S. Nioka, K. A. Kang, \Dedication: Britton Chance, M.D., Ph.D., D.Sc.," Adv. Exp. Med. Biol. 765, v–xiv (2013). 2. L. Leydesdor®, \Eugene Gar¯eld and algorithmic historiography: Co-words, co-authors, and journal names," Ann Library Inform. Stud. 57, 248–260 (2010). Citation analysis of the scienti¯c publications of Britton Chance 1430003-11 J. I nn ov . O pt . H ea lt h S ci . 2 01 4. 07 . D ow nl oa de d fr om w w w .w or ld sc ie nt if ic .c om by U N IV E R S IT Y O F A M S T E R D A M o n 12 /1 6/ 14 . F or p er so na l us e on ly . 3. B. Chance, J. Brainerd, F. Cajori, G. Millikan, \The kinetics of the enzyme-substrate compound of per- oxidase and their relation to the Michaelis theory," Science 92, 455 (1940). 4. B. Chance, \The kinteics of the enzyme-substrate compound of peroxidase," J. Biol. Chem. 151, 553– 577 (1943). 5. H. Theorell, B. Chance, \Studies on liver alcohol dehydrogenase. II. The kinetics of the compound of horse liver alcohol dehydrogenase and reduced diphosphopyridine nucleotide," Acta Chem. Scand. 5, 1127–1144 (1951). 6. B. Chance, \Rapid and sensitive spectropho- tometry. III. A double beam apparatus," Rev. Sci. Instrum. 22, 634–638 (1951). 7. B. Chance, \An intermediate compound in the catalase-hydrogen peroxide reaction," Acta Chem. Scand. 1, 236–267 (1947). 8. B. Chance, G. R. Williams, \Respiratory enzymes in oxidative phosphorylation. I. Kinetics of oxygen utilization," J. Biol. Chem. 217, 383–393 (1955). 9. B. Chance, G. R. Williams, \Respiratory enzymes in oxidative phosphorylation. II. Di®erence spectra," J. Biol. Chem. 217, 395–407 (1955). 10. B. Chance, G. R. Williams, \Respiratory enzymes in oxidative phosphorylation. III. The steady state," J. Biol. Chem. 217, 409–427 (1955). 11. B. Chance, G. R. Williams, \Respiratory enzymes in oxidative phosphorylation. IV. The respiratory chain," J. Biol. Chem. 217, 429–438 (1955). 12. B. Chance, B. Hess, \Metabolic control mechanisms. IV. The e®ect of glucose upon the steady state of respiratory enzymes in the ascites cell," J. Biol. Chem. 234, 2421–2427 (1959). 13. B. Chance, B. Hess, \Metabolic control mechanisms. III. Kinetics of oxygen utilization in ascites tumor cells," J. Biol. Chem. 234, 2416–2420 (1959). 14. B. Chance, B. Hess, \Metabolic control mechanisms. II. Crossover phenomena in mitochondria of ascites tumor cells," J. Biol. Chem. 234, 2413–2415 (1959). 15. B. Chance, B. Hess, \Metabolic control mechanisms. I. Electron transfer in the mammalian cell," J. Biol. Chem. 234, 2404–2412 (1959). 16. B. Chance, D. Gar¯nkel, J. Higgins, B. Hess, \Metabolic control mechanisms. V. A solution for the equations representing interaction between gly- colysis and respiration in ascites tumor cells," J. Biol. Chem. 235, 2426–2439 (1960). 17. B. Hess, B. Chance, \Metabolic control mechanisms. VI. chemical events after glucose addition to ascites tumor cells," J. Biol. Chem. 236, 239–246 (1961). 18. B. Chance, H. Baltsche®sky, \Respiratory enzymes in oxidative phosphorylation. VII. Binding of intramitochondrial reduced pyridine nucleotide," J. Biol. Chem. 233, 736–739 (1958). 19. B. Chance, F. Jobsis, \Changes in °uorescence in a frog sartorius muscle following a twitch," Nature 184, 195–196 (1959). 20. B. Chance, B. Schoener, P. Cohen, F. Jobsis, \Localized °uorometry of oxidation-reduction states of intracellular pyridine nucleotide in brain and kidney cortex of anesthetized rat," Science 136, 325 (1962). 21. B. Chance, P. Cohen, F. Jobsis, B. Schoener, \Intracellular oxidation-reduction states in vivo," Science 137, 499–508 (1962). 22. B. Chance, B. Schoener, \Correlation of oxidation- reduction changes of intracellular reduced pyridine nucleotide and changes in electroencephalogram of the rat in anoxia," Nature 195, 956–958 (1962). 23. D. DeVault, B. Chance, \Studies of photosynthesis using a pulsed laser. I. Temperature dependence of cytochrome oxidation rate in chromatium. Evidence for tunneling," Biophys. J. 6, 825–847 (1966). 24. N. S. Scrutton, M. J. Sutcli®e, P. Leslie Dutton, \Quantum catalysis in enzymes: Beyond the tran- sition state theory paradigm. A Discussion Meeting held at the Royal Society on 14 and 15 November 2005," J. R. Soc. Interface / the R. Soc. 3, 465–469 (2006). 25. B. Chance, L. Ernster, P. B. Garland, C. P. Lee, P. A. Light, T. Ohnishi, C. I. Ragan, D. Wong, \Flavoproteins of the mitochondrial respiratory chain," Proc. Natl. Acad. Sci. USA 57, 1498–1505 (1967). 26. P. B. Garland, B. Chance, L. Ernster, C. P. Lee, D. Wong, \Flavoproteins of mitochondrial fatty acid oxidation," Proc. Natl. Acad. Sci. USA 58, 1696– 1702 (1967). 27. I. Hassinen, B. Chance, \Oxidation-reduction prop- erties of the mitochondrial °avoprotein chain," Bio- chem. Biophys. Res. Commun. 31, 895–900 (1968). 28. M. V. Gilmour, M. R. Lemberg, B. Chance, \Cytochrome oxidase and its derivatives. IX. Spec- trophotometric studies on the rapid reaction of fer- rous cytochrome c oxidase with molecular oxygen under conditions of complete and partial oxy- genation," BBA — Bioenergetics 172, 37–51 (1969). 29. B. Chance, \Cytochromes: Chemical and structural aspects," Science 159, 654–658 (1968). 30. B. Chance, C. Saronio, J. S. Leigh Jr, \Functional intermediates in the reaction of membrane bound cytochrome oxidase with oxygen," J. Biol. Chem. 250, 9226–9237 (1975). 31. B. Chance, \The energy-linked reaction of calcium with mitochondria," J. Biol. Chem. 240, 2729–2748 (1965). 32. G. Loschen, L. Floh�e, B. Chance, \Respiratory chain linked H2O2 production in pigeon heart mitochondria," FEBS Lett. 18, 261–264 (1971). L. Z. Li et al. 1430003-12 J. I nn ov . O pt . H ea lt h S ci . 2 01 4. 07 . D ow nl oa de d fr om w w w .w or ld sc ie nt if ic .c om by U N IV E R S IT Y O F A M S T E R D A M o n 12 /1 6/ 14 . F or p er so na l us e on ly . 33. B. Chance, S. Ele®, J. S. Leigh, Jr., \Noninvasive, nondestructive approaches to cell bioenergetics," Proc. Natl. Acad. Sci. USA 77, 7430–7434 (1980). 34. P. B. Garlick, G. K. Radda, P. J. Seeley, B. Chance, \Phosphorus NMR studies on perfused heart," Biochem. Biophy. Res. Commun. 74, 1256–1262 (1977). 35. B. Chance, G. Radda, P. J. Seeley, I. Silver, Y. Nakase, M. Bond, G. McDonald, \31P NMR of excised and in situ brain tissues," in NMR and Biochemistry: A Symposium Honoring Mildred Cohn, S. Opella & P. Lu, Eds., pp. 269–281, Marcel Dekker, Inc., New York (1979). 36. A. C. McLaughlin, H. Takeda, B. Chance, \Rapid ATP assays in perfused mouse liver by 31P NMR," Proc. Natl. Acad. Sci. USA 76, 5445–5449 (1979). 37. J. Cohen, \Scientists who fund themselves," Science 279, 178–181 (1998). 38. A. Boveris, B. Chance et al., \Enhancement of the chemiluminescence of perfused rat liver and of iso- lated mitochondria and microsomes by hydro- peroxides," Adv. Exp. Med. Biol. 2, 975–984 (1978). 39. A. Boveris, E. Cadenas, R. Reiter, M. Filipkowski, Y. Nakase, B. Chance, \Organ chemiluminescence: Noninvasive assay for oxidative radical reactions," Proc. Natl. Acad. Sci. USA 77, 347–351 (1980). 40. E. Cadenas, A. I. Varsavsky, A. Boveris, B. Chance, \Low level chemiluminescence of the cytochrome c-catalyzed decomposition of hydrogen peroxide," FEBS Lett. 113, 141–144 (1980). 41. E. Cadenas, R. P. Daniele, B. Chance, \Low level chemiluminescence of alveolar macrophages: Spec- tral evidence for singlet oxygen generation," FEBS Lett. 123, 225–228 (1981). 42. A. Greer, \Christopher Foote's discovery of the role of singlet oxygen [ 1O2 ( 1�g)] in photosensitized oxidation reactions," Acc. Chem. Res. 39, 797–804 (2006). 43. M. J. Thomas, P. S. Shirley, C. C. Hedrick, L. R. DeChatelet, \Role of free radical processes in stimulated human polymorphonuclear leukocytes", Biochemistry 25, 8042–8048 (1986). 44. L. Powers, W. E. Blumberg, B. Chance, C. H. Barlow, J. Leigh, J. S., J. Smith, T. Yonetani, S. Vik, \Structure and function of copper atoms in cytochrome oxidase," Adv. Exp. Med. Biol. 2, 863– 871 (1978). 45. L. Powers, W. E. Blumberg, B. Chance, C. H. Barlow, J. S. Leigh, Jr., J. Smith, T. Yonetani, S. Vik, J. Peisach, \The nature of the copper atoms of cytochrome c oxidase as studied by optical and x-ray absorption edge spectroscopy," Biochim. Biophys. Acta 546, 520–538 (1979). 46. J. Peisach, L. Powers, W. E. Blumberg, B. Chance, \Stellacyanin. Studies of the metal-binding site using x-ray absorption spectroscopy," Biophys. J. 38, 277–285 (1982). 47. B. Chance, R. Fischetti, L. Powers, \Structure and kinetics of the photoproduct of carboxymyoglobin at low temperatures: An X-ray absorption study," Biochemistry 22, 3820–3829 (1983). 48. L. Garcia-Iniguez, L. Powers, B. Chance, S. Sellin, B. Mannervik, A. S. Mildvan, \X-ray absorption studies of the Zn 2þ site of glyoxalase I," Biochem- istry 23, 685–689 (1984). 49. B. Chance, J. S. Leigh, H. Miyake, D. S. Smith, S. Nioka, R. Greenfeld, M. Finander, K. Kaufmann, W. Levy, M. Young, \Comparison of time-resolved and -unresolved measurements of deoxyhemoglobin in brain," Proc. Natl. Acad. Sci. USA 85, 4971–4975 (1988). 50. B. Chance, S. Nioka, J. Kent, K. McCully, M. Fountain, R. Greenfeld, G. Holtom, \Time-resolved spectroscopy of hemoglobin and myoglobin in rest- ing and ischemic muscle," Anal. Biochem. 174, 698– 707 (1988). 51. M. S. Patterson, B. Chance, B. C. Wilson, \Time resolved re°ectance and transmittance for the non- invasive measurement of tissue optical properties," Appl. Opt. 28, 2331–2336 (1989). 52. M. A. O'Leary, D. A. Boas, B. Chance, A. G. Yodh, \Refraction of di®use photon density waves," Phys. Rev. Lett. 69, 2658–2661 (1992). 53. D. A. Boas, M. A. O'Leary, B. Chance, A. G. Yodh, \Scattering of di®use photon density waves by spherical inhomogeneities within turbid media: Analytic solution and applications," Proc. Natl. Acad. Sci. USA 91, 4887–4891 (1994). 54. X. Li, B. Beauvoit, R. White, S. Nioka, B. Chance, A. G. Yodh, Optical Tomography, Photon Mi- gration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumenta- tion Tumor Localization Using Fluorescence of Indocyanine Green(ICG) in Rat Models, Vol. 789 SPIE, San Jose, CA, USA (1995). 55. A. Yodh, B. Chance, \Spectroscopy and imaging with di®using light," Phys. Today 48, 34–40 (1995). 56. X. D. Li, T. Durduran, A. G. Yodh, B. Chance, D. N. Pattanayak, \Di®raction tomography for bio- chemical imaging with di®use-photon density waves," Opt. Lett. 22, 573–575 (1997). 57. V. Ntziachristos, X. Ma, A. G. Yodh, B. Chance, OSA Trends in Optics and Photonics, E. M. Sevick- Muraca, J. A. Izatt, M. N. Ediger, Eds., Quanti- tation of Functional Motor Cortex Activity using Time-Resolved Spatially Localized NIR Spec- troscopy, pp. 200–204, Optical Society of America, Washington, DC (1998). 58. V. Ntziachristos, A. G. Yodh, M. D. Schnall, B. Chance, \MRI-guided di®use optical spectroscopy Citation analysis of the scienti¯c publications of Britton Chance 1430003-13 J. I nn ov . O pt . H ea lt h S ci . 2 01 4. 07 . D ow nl oa de d fr om w w w .w or ld sc ie nt if ic .c om by U N IV E R S IT Y O F A M S T E R D A M o n 12 /1 6/ 14 . F or p er so na l us e on ly . of malignant and benign breast lesions," Neoplasia 4, 347–354 (2002). 59. G. Yu, T. Durduran, G. Lech, C. Zhou, B. Chance, E. R. Mohler, 3rd, A. G. Yodh, \Time-dependent blood °ow and oxygenation in human skeletal muscles measured with noninvasive near-infrared di®use optical spectroscopies," J. Biomed. Opt. 10, 024027 (2005). 60. X. Intes, B. Chance, M. J. Holboke, A. G. Yodh, \Interfering di®usive photon-density waves with an absorbing-°uorescent inhomogeneity," Opt. Express 8, 223–231 (2001). 61. A. Villringer, B. Chance, \Non-invasive optical spectroscopy and imaging of human brain function," Trends Neurosci. 20, 435–442 (1997). 62. D. M. Mancini, L. Bolinger, H. Li, K. Kendrick, B. Chance, J. R. Wilson, \Validation of near-infrared spectroscopy in humans," J. Appl. Physiol. 77, 2740–2747 (1994). 63. E. M. Sevick, B. Chance, J. Leigh, S. Nioka, M. Maris, \Quantitation of time- and frequency-resolved opti- cal spectra for the determination of tissue oxy- genation," Anal. Biochem. 195, 330–351 (1991). 64. V. Ntziachristos, A. G. Yodh, M. Schnall, B. Chance, \Concurrent MRI and di®use optical tom- ography of breast after indocyanine green enhancement," Proc. Natl. Acad. Sci. USA 97, 2767–2772 (2000). 65. G. Zheng, H. Li, K. Yang, D. Blessington, K. Licha, S. Lund-Katz, B. Chance, J. D. Glickson, \Tricarbocyanine cholesteryl laurates labeled LDL: New near infrared °uorescent probes (NIRFs) for monitoring tumors and gene therapy of familial hypercholesterolemia," Bioorg. Med. Chem. Lett. 12, 1485–1488 (2002). 66. M. Zhang, Z. Zhang, D. Blessington, H. Li, T. M. Busch, V. Madrak, J. Miles, B. Chance, J. D. Glickson, G. Zheng, \Pyropheophorbide 2-deox- yglucosamide: A new photosensitizer targeting glu- cose transporters," Bioconjug. Chem. 14, 709–714 (2003). 67. J. Chen, K. Ste®lova, M. J. Niedre, B. C. Wilson, B. Chance, J. D. Glickson, G. Zheng, \Protease-trig- gered photosensitizing beacon based on singlet oxygen quenching and activation," J. Am. Chem. Soc. 126, 11450–11451 (2004). 68. Z. Zhang, D. Blessington, H. Li, T. M. Busch, J. Glickson, Q. Luo, B. Chance, G. Zheng, \Redox ratio of mitochondria as an indicator for the re- sponse of photodynamic therapy," J. Biomed. Opt. 9, 772–778 (2004). 69. Z. Zhang, H. Li, Q. Liu, L. Zhou, M. Zhang, Q. Luo, J. Glickson, B. Chance, G. Zheng, \Metabolic imaging of tumors using intrinsic and extrinsic °u- orescent markers," Biosens. Bioelectron. 20, 643– 650 (2004). 70. L. Z. Li, R. Zhou, H. N. Xu, L. Moon, T. Zhong, E. J. Kim, H. Qiao, R. Reddy, D. Leeper, B. Chance, J. D. Glickson, \Quantitative magnetic resonance and optical imaging biomarkers of melanoma metastatic potential," Proc. Natl. Acad. Sci. USA 106, 6608– 6613 (2009). 71. L. Z. J. Li, R. Zhou, T. Zhong, L. Moon, E. J. Kim, H. Qiao, S. Pickup, M. J. Hendrix, D. Leeper, B. Chance, J. D. Glickson, \Predicting melanoma metastatic potential by optical and magnetic res- onance imaging," Adv. Exp. Med. Biol. 599, 67–78 (2007). 72. H. N. Xu, S. Nioka, J. D. Glickson, B. Chance, L. Z. Li, \Quantitative mitochondrial redox imaging of breast cancer metastatic potential," J. Biomed. Opt. 15, 036010 (2010). 73. H. N. Xu, J. Tchou, B. Chance, L. Z. Li, \Imaging the redox states of human breast cancer core biopsies," Adv. Exp. Med. Biol. 765, 343–349 (2013). 74. H. N. Xu, R. C. Addis, D. F. Goings, S. Nioka, B. Chance, J. D. Gearhart, L. Z. Li, \Imaging redox state heterogeneity within individual embryonic stem cell colonies," J. Innov. Opt. Health Sci. 4, 279–288 (2011). 75. J.-R. Horng, S. Nioka, A. Quo, B. Chance, \A novel time-shared °uorometer gives the mitochondrial redox state as the ratio of two components of the respiratory chain of the animal and human buccal cavity with quantitative measures of the redox energy state," J. Innov. Opt. Health Sci. 3, 235–245 (2010). 76. B. Chance, H. Sies, A. Boveris, \Hydroperoxide metabolism in mammalian organs," Physiol. Rev. 59, 527–605 (1979). 77. A. Boveris, B. Chance, \The mitochondrial gener- ation of hydrogen peroxide. General properties and e®ect of hyperbaric oxygen," Biochem. J. 134, 707– 716 (1973). 78. B. Chance, G. R. Williams, \The respiratory chain and oxidative phosphorylation," Adv. Enzymol. Relat. Subj. Biochem. 17, 65–134 (1956). 79. B. Chance, A. C. Maehly, \Assay of catalases and peroxidases," Methods Enzymol. 2, 764–775 (1955). 80. B. Chance, \Spectra and reaction kinetics of res- piratory pigments of homogenized and intact cells," Nature 169, 215–221 (1952). 81. B. Chance, \Spectrophotometry of intracellular res- piratory pigments," Science 120, 767–775 (1954). L. Z. Li et al. 1430003-14 J. I nn ov . O pt . H ea lt h S ci . 2 01 4. 07 . D ow nl oa de d fr om w w w .w or ld sc ie nt if ic .c om by U N IV E R S IT Y O F A M S T E R D A M o n 12 /1 6/ 14 . F or p er so na l us e on ly . Citation analysis of the scientific publications of Britton Chance in ISI citation indexes 1. Introduction to Britton Chance 2. Scientometric Analysis 3. Discussion and Summary References work_76d3vxwg7nasxhrl7arzxzfovm ---- wp-p1m-39.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-39.ebi.ac.uk no 218196983 Params is empty 218196983 exception Params is empty 2021/04/06-02:09:22 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. Message ID: 218196983 (wp-p1m-39.ebi.ac.uk) Time: 2021/04/06 02:09:22 If you need further help, please send an email to PMC. Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_76vd3ckiprc5reccwb3bxo2wti ---- 60 1 1 July 1970 Leading Articles REDICAL JOURNAL pericarditis is active. Sometimes the pericarditis is present without any E.C.G. changes.5 About half the patients reported on by Kirk and Cosh also had rheumatoid lung or pleural lesions.5 Pleural effusion is common, but pericardial effusion is rare. In the few cases in which pericardial effusion occurs the fluid closely resembles the straw-coloured non-viscous fluid found in the pleural cavity; typically it is high in protein but low in sugar. L.E. cells are found in the blood in a minority of patients,6 but even then the diagnosis of rheumatoid arthritis as opposed to systemic lupus erythematosus is usually clear. To assess the incidence of rheumatoid pericarditis Kirk and Cosh made a prospective study of 100 inpatients with severe rheumatoid arthritis selected at random. They found it was 10%. But their patients had sufficiently severe disease to warrant admission to hospital, and so high an incidence would not be expected in patients outside hospital. The prognosis of rheumatoid pericarditis is generally good. The condition appears to run a benign course, usually with rapid spontaneous resolution. Specific therapy does not prevent its onset or shorten its course once established. If pericardial effusion occurs, early aspiration is advised to prevent tamponade and to reduce the risk of later pericardial constriction. B. P. Harrold7 reviewed 17 reported patients with rheumatoid pericarditis who had undergone pericardi- ectomy for constriction and noted that in only three did the interval between onset of arthritis and operation exceed five years. This suggests that if constriction is going to occur it is unlikely to do so in patients with arthritis of long duration. Rarely, heart failure may be the presenting symptom of rheumatoid pericarditis, and the onset of oedema in a patient with rheumatoid arthritis should prompt the doctor to consider this possibility. Children's Eyes Errors of refraction are almost universal, and few of us attain old age without recourse to spectacles. Yet, though the refractive state of the eye is simply the product of physical variations in the eye's anatomy which admit an exact measurement, our knowledge of these measurements in sub- stantial numbers of the population at different ages has been very incomplete. A recent comprehensive report by Arnold Sorsby and G. A. Leary' is welcome not only because of the information it provides on the patterns of refractive changes in growing children but also because it helps to clear away some of the myths that are still being reported about the prophylaxis and "treatment" of short-sightedness. The infant's eye is normally hypermetropic (long-sighted), and as the eyeball grows in length the hypermetropia decreases. The eye thus becomes more normal-sighted or even short- sighted until growth comes to an end by the age of 14. Between the ages of 3 and 14 the eye becomes about 1*2 mm. larger. But some 60% of the potential decrease in hyper- metropia (or increase in myopia) that this elongation could be expected to produce is eliminated by a simultaneous reduction in the converging power of the cornea and lens, so Sorsby, A., and Leary, G. A., Medical Research Council. Special Report Series, 1970, No. 309. 2 Sorsby, A., Sheridan, M., and Leary, G. A., Medical Research Council. Special Report Series, 1962, No. 303. 3 Morgan, O., British Medical_Journal, 1970, 1, 175. 4 Gilkes, M. J., British MedicalJournal, 1970, 1, 758. that the resultant change in refraction is little more than 1 dioptre. And, as most infants are more than 1 dioptre hyper- metropic, only exceptionally does this trend produce a frank myopia, and that of quite a low order. In about 28% of children a greater elongation of the eyeball during this growth period does cause a further shift towards myopia than can be compensated for by a slight additional decrease of the power of the cornea and lens. The change in cornea and lens is in part the direct sequel to this elongation and would itself tend to neutralize some of this adventitious myopia. The authors of the report found that bodily heights and weights were unrelated to the refraction at the beginning and end of the period ofobservation, and there were no obvious sex differences in these developments. As the authors had shown in an earlier report,2 the refraction and its components are genetically determined. And this, they state, must be assumed to apply also to the anomalous axial elongation and paradoxical changes in the cornea and lens. The provision of correct spectacles will thus have no influence on this predetermined refractive change3 4 any more than on other organic disorders of the eyeball. Caribbean Food and Nutrition Institute Christopher Columbus made his first landfall in the Caribbean in October 1492 at an island in the Bahamas which he piously named San Salvador. Believing he had reached Asia, he imposed on posterity the confusing practice of calling the people of the New World "Indians" and the Caribbean islands the "West Indies." The area was at that time inhabited by the gentle Arawaks and the fierce Caribs, who gave us the word "cannibal." The Arawaks were soon exterminated by the Europeans who followed Columbus; the Caribs held out somewhat longer, and a few thousand survive today. In the sixteenth and seventeenth centuries the islands were appropriated by European powers-the English, French, Dutch, and Spanish. They became sugar islands, devoted to sugar plantations worked by negro slaves captured in West Africa and carried across the Atlantic in the dreadful circum- stances of the middle passage. After emancipation in the nineteenth century the sugar industry declined because the ex-slaves hated the sight of the sugar cane, which was being grown in increasing quantities in other parts of the tropics, and the sugar beet, efficiently cultivated in the temperate zone, began to rival the cane as a source of sucrose. During a long period of economic depression the Caribbean territories faded out of history, becoming of little importance to their European owners. Partial economic recovery came only recently, with the development of new industries such as bauxite manufac- ture, and the discovery, by wealthy Canadians and Americans, that the Caribbean offers an escape from winter blizzards and has lovely scenery. The tourist industry has boomed. During the last decade many of the Caribbean territories have become independent members of the United Nations. This, roughly, is the setting of the Caribbean Food and Nutrition Institute, established in 1967. The institute has centres in Jamaica and Trinidad, each located in the campus of the University of the West Indies. At present its activities I'Journal of Tropical Pediatrics, 1968, 14, 52. 2 Waterlow, J. C., Cravioto, J., and Stephen, J. M. L., Advances in Protein Chemistry, 1969, 15, 131. o n 5 A p ril 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://w w w .b m j.co m / B r M e d J: first p u b lish e d a s 1 0 .1 1 3 6 /b m j.3 .5 7 1 4 .6 0 o n 1 1 Ju ly 1 9 7 0 . D o w n lo a d e d fro m http://www.bmj.com/ work_7agtj4z7w5eorbwbfedwhzlxbq ---- wp-p1m-38.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-38.ebi.ac.uk no 218193178 Params is empty 218193178 exception Params is empty 2021/04/06-02:09:17 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. Message ID: 218193178 (wp-p1m-38.ebi.ac.uk) Time: 2021/04/06 02:09:17 If you need further help, please send an email to PMC. Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_7g5pcnv7mfcvlgobmwsz223qge ---- Nonlinear Physics of Ecosystems Physics Today Nonlinear Physics of Ecosystems Hugo Fort Citation: Physics Today 68(10), 46 (2015); doi: 10.1063/PT.3.2949 View online: http://dx.doi.org/10.1063/PT.3.2949 View Table of Contents: http://scitation.aip.org/content/aip/magazine/physicstoday/68/10?ver=pdfcov Published by the AIP Publishing This article is copyrighted as indicated in the article. Reuse of AIP content is subject to the terms at: http://scitation.aip.org/termsconditions. Downloaded to IP: 164.73.83.101 On: Thu, 01 Oct 2015 22:06:59 http://oasc12039.247realmedia.com/RealMedia/ads/click_lx.ads/www.aip.org/pt/adcenter/pdfcover_test/L-37/452059625/x01/AIP-PT/KNF_ArticleDL_092315/PhysicsToday_DD_pumps_1640x440_banner-2.jpg/6c527a6a713149424c326b414477302f?x http://scitation.aip.org/content/aip/magazine/physicstoday?ver=pdfcov http://scitation.aip.org/search?value1=Hugo+Fort&option1=author http://scitation.aip.org/content/aip/magazine/physicstoday?ver=pdfcov http://dx.doi.org/10.1063/PT.3.2949 http://scitation.aip.org/content/aip/magazine/physicstoday/68/10?ver=pdfcov http://scitation.aip.org/content/aip?ver=pdfcov 46 October 2015 Physics Today www.physicstoday.org books A Beautiful Question Finding Nature’s Deep Design Frank Wilczek Penguin Press, 2015. $29.95 (430 pp.). ISBN 978-1-59420-526-2 Reviewed by Sabine Hossenfelder My four-year-old daughter recently dis- covered that equilateral triangles com- bine to form larger equilateral triangles. When I caught a distracted glimpse of her artwork, I thought she had drawn the baryon decuplet, an often-used dia- gram to depict relations between some of the particles composed of three quarks. The baryon decuplet doesn’t come easy to humans, but the beauty of sym- metry does. And how amazing it is that physicists have found symmetry tightly woven into the fabric of nature itself: Both the standard model of particle physics and general relativity, currently our most fundamental theories, are in essence mathematically precise imple- mentations of symmetry requirements. Next to being instrumental for the accurate description of nature, symme- tries are also universally appealing to humans, as reflected in art and design across cultures. For the physicist, it is second nature to see the equations be- hind the art. Indeed, having that ability may be considered either a curse or a blessing. To Frank Wilczek, it clearly is a bless- ing. In A Beautiful Question: Finding Nature’s Deep Design he highlights the success of symmetries in physics and goes on to answer the question of whether “the world embodies beautiful ideas” with an emphatic “Yes.” Wilczek starts from the discovery of basic math- ematical relationships like Pythagoras’s theorem (and doesn’t shy away from proving it!) and proceeds through the history of physics, stopping to consider such milestone topics as musical har- monies, the nature of light and the basics of optics, Newtonian gravity and its extension to general relativ- ity, quantum mechanics, and ultimately the standard model of particle physics. He touches briefly on condensed-matter physics—graphene in particu- lar—and takes an interesting detour into the human eye’s limited ability to decode visual information. In the last chapters of the book, Wilczek goes into quite some detail about the particle content of the stan- dard model and how, it seems, the model is not as beautiful as one may have hoped. He introduces the reader to extended theories such as grand unification and also supersymmetry, which was invented to remedy some of the supposed shortcomings of the standard model. The reader unfamiliar with the quantum numbers used to classify elementary particles will likely find some parts of that section a bit demanding. But whether or not one makes the effort to follow the details, Wilczek gets his message across clearly: Striving for beauty in natural law has been a useful guide, and he expects it to remain one. He is, however, careful to note that relying on beauty has, on various occa- sions, led to plainly wrong theories, such as an explanation of planetary orbits in terms of Platonic solids or a theory of atoms based on the mathe- matics of knots. A Beautiful Question is a skillfully written reflection, or “meditation,” as Wilczek puts it. It is well structured and accompanied by many figures, includ- ing two inserts with color prints. The book also contains an extensive glos- sary, recommendations for further reading, and a timeline of discoveries mentioned in the text. The content of the book is unique in the genre of popular works. Dave Goldberg’s The Universe in the Rearview Mirror: How Hidden Symmetries Shape Reality (Dutton, 2013), for example, also discusses the role of symmetries in fun- damental physics, but Wilczek gives more space to the connection between aesthetics in art and science. A Beautiful Question picks up and expands on the theme of Steven Weinberg’s book, Dreams of a Final Theory (Pantheon, 1992), which also expounds on the rel- evance of beauty in the development of physical theories. More than 20 years have passed since Weinberg wrote his book, but the dream is still as elusive today as it was back then. For all its elaboration on the beauty of symmetry, Wilczek’s book falls short of spelling out a conundrum physicists face today: We have no reason to be confi- dent that the laws of nature yet to be discovered will conform to the human sense of beauty. Nor does Wilczek spend many words on aspects of beauty beyond symmetry; he only briefly touches on fractals, and never goes into the rich appeal of chaos and complexity. My mother used to say that “sym- metry is the art of the dumb,” a criticism perhaps too harsh to level at the stan- dard model. But seeing that reliance on beauty has not helped us in the past two decades, maybe it is time to consider that a beautiful answer might not reveal itself as effortlessly as does the appeal of plane tilings to a four-year-old. Maybe the inevitable subjectivity in our sense of aesthetic appeal will turn out to be a curse, misleading us as to where the answers lie. Wilczek’s book contains something for every reader, from the physicist who wants to learn how a Nobel Prize win- ner thinks of the connection between ideas and reality to the layman who wants to know more about the structure of fundamental laws. A Beautiful Ques- tion reminds us of the many ways that science connects to the arts, and it in- vites us to marvel at the success our species has had in unraveling the mys- teries of nature. Nonlinear Physics of Ecosystems Ehud Meron CRC Press, 2015. $89.95 (344 pp.). ISBN 978-1-4398-2631-7 Many concepts and methods from non- linear physics have proved to be useful for addressing important problems in ecology. Indeed, a growing number of physicists are working with ecologists and are making significant contribu- tions to ecology. Pattern formation and spatial ecology—how those patterns are related to ecological phenomena—are particular research areas that benefit The allure of the aesthetic Sabine Hossenfelder is an assistant professor of high-energy physics at Nordita, the Nordic Institute for Theoretical Physics, in Stockholm. She works on physics beyond the standard model and on quantum- gravity phenomenology, and she blogs at http://backreaction.blogspot.com. This article is copyrighted as indicated in the article. Reuse of AIP content is subject to the terms at: http://scitation.aip.org/termsconditions. Downloaded to IP: 164.73.83.101 On: Thu, 01 Oct 2015 22:06:59 October 2015 Physics Today 49 from the interdisciplinary inter- actions. For example, field ob- servations of vegetation pat- terns in arid and semiarid regions have revealed patterns similar to ones found in fluid dynamics and nonlinear optics. Any book that attempts to bridge ecology and nonlinear physics would be welcomed by scien- tists who work at the intersection of both fields. In my own work, I have col- laborated with ecologists to develop quantitative methods and models to address biodiversity dynamics and spatiotemporal early warning signals of catastrophic shifts in ecosystems. I have also taught courses for mixed audiences of agronomists, ecologists, and physicists. I was greatly impressed by the vari- ety of topics covered in Ehud Meron’s Nonlinear Physics of Ecosystems and by the depth in which they are discussed. The author’s introduction to each topic is clear, and the book’s overall organiza- tion makes it easily readable. At the be- ginning of each chapter is an outline of the major points treated, and at the end, a summary of the key ideas that were developed. The bibliography is exten- sive and comprehensive. I found few omissions. The most significant one would be James Murray’s classic text Mathematical Biology II: Spatial Models and Biomedical Applications (Springer, 2003), which, although it does not focus on spatial ecology, has substantial over- lap with this book. Nonlinear Physics of Ecosystems also contains many figures and photos that help readers to visual- ize spatial patterns in real eco systems. All that makes Meron’s book an im - portant reference, particularly for re- searchers of spatial self-organization and spatial ecology. The book is divided into three parts. The first begins with a quite standard presentation of the basics of self- organization in nonequilibrium sys- tems. It then offers a qualitative review of spatial ecology and presents out- standing problems such as desertifi - cation and biodiversity loss. The con- cluding chapter for that section raises important and broadly relevant ques- tions about ecosystem modeling: Why model? How should a model be set up? What is the significance of qualitative information? Such questions should be considered by anyone who conducts scientific research and uses models. The second part is devoted to pat- tern formation theory, which, according to Meron, is a missing link in ecological research. In fact, the book’s main pur- pose is to fill that gap; in essence, part two is the book’s nucleus. The author presents basic and advanced methods related to the main types of pattern formation mechanisms. Among the plethora of struc- tures are stripe and hexagonal patterns, scale-free patterns, and spiral waves. The third part considers different applications of pattern formation the- ory to spatial ecology. The author ex- plains the significance of self- organized vegetation patchiness to paramount ecological problems presented in the first part, including desertification and biodiversity loss in changing environ- ments. I enjoyed reading the two final chapters—11 and 12—which cover topics I have been working on, namely, regime shifts, desertification, and species coexistence and diversity in plant communities. Particularly well done were the discussions on different early warning signals of regime shifts and their spatial aspects. I enjoyed the explanation of species coexistence in- duced by plants that act as ecosystem engineers by modifying their physical 20+ years serving the scientific & engineering community NEW VERSION Over 100 new features & improvements in Origin 2015! FOR A FREE 60-DAY EVALUATION, GO TO ORIGINLAB.COM/DEMO AND ENTER CODE: 2876 Over 500,000 registered users worldwide in: ◾ 6,000+ Companies including 120+ Fortune Global 500 ◾ 6,500+ Colleges & Universities ◾ 3,000+ Government Agencies & Research Labs This article is copyrighted as indicated in the article. Reuse of AIP content is subject to the terms at: http://scitation.aip.org/termsconditions. Downloaded to IP: 164.73.83.101 On: Thu, 01 Oct 2015 22:06:59 50 October 2015 Physics Today www.physicstoday.org books environment and in certain circum- stances facilitating the growth of other species. Nonlinear Physics of Ecosystems surely will contribute to the development of a newly emerging interdisciplinary re- search field at the interface of ecology and pattern formation. I would recom- mend it to graduate students who want to conduct research in mathematical ecology or physics applied to spatial- ecology problems. A minor caveat: I wish the book had included exercises to help students reinforce and test their understanding; maybe it will in the next edition. Nonetheless, it could be used either as a main or supporting textbook in a one-semester course for advanced un- dergraduate or graduate students in physics or ecology or in a course with a mixed audience of students from both disciplines. I also warmly recommend the book for nonlinear physicists, ap- plied mathematicians, and theoretical ecologists working on those cutting- edge environmental interdisciplinary problems. Hugo Fort University of the Republic Montevideo, Uruguay Particle Accelerators From Big Bang Physics to Hadron Therapy Ugo Amaldi Springer, 2015. $34.99 (284 pp.). ISBN 978-3-319-08869-3 Particle Accelerators: From Big Bang Physics to Hadron Therapy takes us on a fascinating odyssey of accelerator history and applications. Author and prominent CERN scientist Ugo Amaldi’s principal aim is to highlight and praise the role of the machine builders. In doing so, he borrows a comparison made by particle theorist Victor Weiss - kopf, CERN director general from 1961 to 1965. Weisskopf likens accelerator builders to the creators and captains of the ships that brought Christopher Columbus and his crew to the Ameri- cas; experimentalists to those who set foot on the new lands and described them; and, somewhat self-mockingly, theorists to those who stayed behind in Europe and made the prediction that Columbus would arrive at India. Amaldi’s book also confirms the view that developments in science are driven by the achievements of many people across many generations, and that we are indeed standing on the shoulders of giants. The first version of Particle Accelerators was published in 2012 and written in Italian. In 2013 it won a science communi- cation award from the Italian Book Association. Following that success, the author consid- erably expanded his text, add - ing many useful details. In its present form, the book contains many recollections of CERN; it would defi- nitely warm the heart of anyone who worked and lived in that wonderful sci- entific mecca. Particle Accelerators, which is aimed at the general public, is filled with intrigu- ing analogies, metaphors, and humor. For example, the author describes the uncertainty principle as the process of taking a “loan of energy” from the “Heisenberg bank,” with the unusual twist that the greater the loan amount, the earlier it matures. He compares the Bevatron at Lawrence Berkeley National Laboratory to a 10 000-ton “cracker of invisible nuts” and electron–positron annihilation to the disappearance of two colliding strawberries giving rise to a flood of bananas or apples. And he suggests what he considers a compact and more meaningful nomenclature for the three neutrinos: neutrino for the electron neutrino, neutretto for the muon neutrino, and neutrotto (or fatter neutrino) for the tau neutrino. After telling the story of the early ac- celerator builders, the book goes on to particle physics, the field that has most benefited from the technology. Topics covered include the standard model and its extensions; dark matter; dark energy; supersymmetry; and string the- ory, which the author believes provides the most likely explanation for symme- try breaking. If a subsequent edition is written, I hope it includes brief and sim- ple descriptions of the many phenom- ena and methods that are mentioned but never explained—for example, syn- chrotron radiation and the supernova standard candles that led to the idea of an accelerating universe. Medical applications are featured in the book’s concluding section, which de- scribes in popular terms the basics of x-ray and particle imaging and tumor treatment. Readers will learn about many technical details and enjoy some intriguing stories along the way. For instance, the first—and for a long time, the only—interest in an early article outlining computerized tomography came from a Swiss center for avalanche research, which wanted to use the technology to find objects—like lost skiers—trapped in snow. Amaldi captures the roman- tic spirit of the early days of par- ticle physics experiments. He also touches on the cooperation and competition between the continents. Surprisingly, at least at the time this edition was pub- lished, all bosons since 1948 had been discovered in Europe and all fermions in America—a peculiar sort of symmetry breaking. The author also occasionally makes what some readers may consider as frank and provocative remarks. For example, he states that the Large Electron–Positron Collider could have discovered the Higgs more than a decade ago had he and his colleagues convinced the CERN directorate to invest substantially in upgrading the superconducting RF cavities. Amaldi also laments that Bruno Touschek and Gersh Budker were not rewarded with the Nobel Prize for their role in the de- velopment of electron–positron collid- ers; he suggests that had the scientists been working in the US—where the main action was—they would have re- ceived the honor. In any case, such com- ments are nicely balanced by wonderful stories of cooperation, such as between Brookhaven National Laboratory and CERN during the building of the CERN Proton Synchrotron. Particle Accelerators culminates with an inspiring story of the development and creation of the Italian National Center for Oncological Hadron Ther- apy, a great achievement for Amaldi, who put an enormous amount of effort and energy into its creation. He is now working to develop a novel linac for proton therapy. These initiatives prove the author’s own maxim that “physics is beautiful and useful.” Andrei Seryi University of Oxford Oxford, UK Gravity Newtonian, Post-Newtonian, Relativistic Eric Poisson and Clifford M. Will Cambridge U. Press, 2014. $80.00 (780 pp.). ISBN 978-1-107-03286-6 Gravity: Newtonian, Post-Newtonian, Rel- ativistic is not the usual relativity text. But it’s the one you need if you actually want to calculate something astrophysi- cal without a supercomputer. I know of no other text that compares with this compendium of tricks for calculating ob- servables in the large fraction of the uni- verse that is not near an event horizon. This article is copyrighted as indicated in the article. Reuse of AIP content is subject to the terms at: http://scitation.aip.org/termsconditions. Downloaded to IP: 164.73.83.101 On: Thu, 01 Oct 2015 22:06:59 work_7hnewwn6azekhkgoshqkaafjr4 ---- An attempt to correlate cattle breed origins and diseases associated with or transmitted by the tick Amblyomma variegatum in the French West Indies J.C. Maillard l S.J. Kemp * M. Naves 3 C. Palin 4 C. Demangel l A. Accipe 5 N. Maillard 6 A. Bensaid 7 STVM-93 I An attempt to correlate cattle breed origins and diseases associated with or transmitted by the tick Amblyomma variegatuh in the French West Indies MAILLARD (J.C.), KEMP, (S.J.), NAVES (M.), PALIN (C.), DEMANGEL (C.), ACCIPE (A.), MAILLARD (N.), BENSAID (A.). Tentative de corrélation de l’origine des races bovines et des maladies associées à ou transmises par la tique Amblyomma vnriegntum dans les Antilles françaises. Revue Eh. Méd. vét. Pays trop., 1993, 46 (l-2) : 283-290 A l’aide de données biologiques et de la recherche historique, on a essayé d’expliquer la différence, en ce qui concerne la résistance et la sensibilité aux maladies transmises par (cowdriose) ou associées à (dermatophilose) la tique AmbZyomma variegatum, entre deux races bovines des Antilles françaises : la race Créole hybride de la Guadeloupe et le zébu Brahman de la Martinique. Les polymor- phismes de 5 systèmes génétiques indépendants (hémoglobine éry- throcytaire, albumine et transferrine du sérum, la région classe 1 du complexe BoLA et le gène gamma S cristallin) ont été étudiés chez différentes races, à savoir des Bos faurus d’Europe et d’Afrique, des Bos indicus d’Afrique de l’Ouest et de l’Est, le Brahman de la Martinique et le Créole de la Guadeloupe. Par comparaison des fré- quences de différents allèles de ces 5 loti polymorphiques non liés et à l’aide de deux matrices mathématiques différentes de NE1 et de CAVALLI-SFORZA, on a établi les distances génétiques entre ces races. Il apparaît clairement que le bovin Créole de la Guadeloupe est dans une position intermédiaire entre le Bos turcrus N’Dama de l’Afrique de l’Ouest et deux races de zébu, Bos indicus, le zébu souda- nais de l’Afrique de l’Ouest et le Brahman. Grace aux études d’archives différentes dans les Caraibes et en Europe, des preuves historiques ont pu être accumulées sur les origines géographiques et sur la chronologie de l’établissement des bovins Créole et Brahman dans les Antilles françaises. La résistance élevée des bovins Créole de la Guadeloupe aux maladies associées à ou transmises par la “tique sénégalaise”, Amblyomma variegatum, semble due à l’héritage d’un lot de gènes de bovins de l’Afrique occidentale, en particulier de la race N’Dama. En effet, la tique A. variegatum, implantée dans toute l’Afrique de l’Ouest, a été introduite dans la région caraïbe avec des bovins ouest-africains. Cette tique a certainement continué à exercer une pression parasitaire, ce qui explique la capacité innée des bov-ins Créole à maîtriser ces maladies spontanément. Mots clés : Bovin - Bovin Créole Bovin N’Dama Zébu Brahman Zébu soudanais - Cowdriose Dermatophilose Tique - Amblyomrnn variegatum - Résistance aux maladies - Antilles françaises Guadeloupe - Martinique. 1. CIRAD-EMVT, Guadeloupe. 2. ILRAD, Nairobi, Kenya. 3. INRA-CRAAG, Guadeloupe. 4. Veterinary Service of Martinique. 5. Veterinary Service of Guadeloupe. 6. Historian, Guadeloupe. 7. CIRAD-EMVT Maisons Alfort, France. INTRODUCTION The Brahman zebu cattle of Martinique is a crossbred population coming from a stabilized mix of different Indian zebu breeds (Gir, Nelore, Gujera) selected in the South of the USA (27, 32) and introduced in this island around 1952. These cattle are very well adapted to the tropical breeding conditions but it is to some extent sus- ceptible to dermatophilosis (5, 11, 12, 26). As a matter of fact, before its introduction in Martinique, this cattle population had never been in contact with the tick Amblyomma variegatum. Also, imported “exotic” European breeds are fully susceptible to dermatophilo- sis and cowdriosis and are in addition not adapted to the tropical conditions. The Creole cattle of Guadeloupe are a population high- ly resistant to dermatophilosis and to cowdriosis (5, Il, 43). Phenotypically, they show a more or less important hump but also several taurine features. This capability to resist diseases associated or transmitted by the “Senegalese” bont tick Amblyomma variegatum is an innate genetic character which is inheritable and proba- bly maintained by a constant parasitic pressure (1, 12, 22, 29, 37, 44). It is known for a long time that these cattle are a cross- bred between 130s taurus and 130s indicus breeds, but this fact presumed by zootechnical and phenotypical observations (5) has never been proved by biological data. Furthermore the ancestral breeds of the Creole cattle have never been clearly identified. We have tried to answer several questions. On the one hand, is the Bos taurus type coming from European breeds, first introduced during the colonization of the West Indies (27), and/or from African taurines introduced later during trade shipping exchanges (16, 41) ? Does the Bos irtdicus type corne from African and/or Indian zebu breeds ? It is evident that if we could answer these questions, we could explain many breeding traits ‘of this Creole popula- tion. Furthermore, it would be possible to include these breeds in comparative studies on genetic research on the improvement of disease resistance and/or zootechnical characters. Revue Élev. Méd. vét. Pays trop., 1993, 46 (l-2) : 283-290 283 Retour au menuRetour au menu J.C. Maillard S.J. Kemp M. Naves C. Palin C. Demangel A. Accipe N. Maillard A. Bensaid MATERIAL AND METHODS Animals The polymorphism of 5 genetic systems in the 9 following breeds have been compared (table 1): - 2 European taurine breeds : 139 Friesian and 212 Jersey ; - 2 African taurine breeds, living in the West African tro- pical area infested by the tick Amblyomma variegatum, and well known to be resistant to several diseases, especially trypanosomosis. These are 1 ,016 shorthorn Baoule of Burkina Faso and 220 longhorn N’Dama of Guinea ; - 167 Creole cattle of Guadeloupe ; - 3 African zebu breeds : 106 Sudan zebus living in the Sahelian area of West Africa, 218 Boran and 393 Kapiti zebus of Kenya in East Africa ; - 121 Brahman zebus from Martinique. TABLEZ Species, geographical origins and numbers of ani- mals sampled in each population of the different breeds studied. L AFRICA West Crossbreed 60s t. indicus GUADELOUPE West AFRICA ~ East MARTINIQUE ! 139 Friesian 212 Jersey 1016 Baoule (shorthorn) 220 N’Dama (longhorn) 167 Creole 106 Sudan 393 Kapiti 218 Boran 121 Brahman Techniques The 5 genetic systems studied were: - the B chain of haemoglobin which is an erythrocytic pro- tein showing 10 electrophoretic variants. The authors have considered the 2 main alleles A and B detected by electrophoresis on a cellulose acetate support, and well known to be good markers of differentiation in the 50s genus between the taurus and indicus species (4, 6, 8, 30, 31, 33,35) ; 284 - the serum albumin displaying 7 variants by polyacryla: mide gel electrophoresis (PAGE). As for haemoglobin, the authors have considered the 2 main alleles ; the F (fast) rather characteristic of Bos taurus breeds, and the S (slow) more frequent in Bas indicus breeds (3, 6, 7, 1.51 19, 33, 36, 38) ; ) - the serum transferrin also analysed by PAGE showing 6 electrophoretic variants : 2 of them (B and F) are known to be specific for Bos indicus zebu breeds (3, 6, 8, 33: 34). The Brahman population of Martinique was not typed for this system ; - the Bovine Major Histocompatibility Complex : BoLA, highly polymorphie, shows in cattle about 50 allo speci- ficities in the class I region (2, 9, 14, 39). These are serologically detected by the standard method of lym- phocytotoxicity. Some antigens of this BoLA class 1, ; region are known to be associated with resistance or susceptibility to several diseases but also 2 of them are ~ ~ specific breed markers (25, 40) when considering ove- rall breed populations. * The KN8 specificity, isolated in Kenya, is a good i3os indicus breed marker (17, 25) . * The KN18 specificity is more interesting because it is, not only a Bos taurus marker but is above all specific for African taurines (17, 25, 42). Its frequency in European taurines and in zebu breeds is low ; - the gamma S crystallin gene, investigated by molecular analysis (18) and showing a bi-allelic polymorphism due to a punctual G/C substitution detected at base number 1754. Indeed, after amplification by the PCR technique and separation by agarose gel electrophoresis, two DNA fragments of 128 and/or 149 bp cari be detected, each’ DNA fragment being representative of one of the two alleles. Mathematical models By using the frequency differences of these 5 polymor- phic loti situated on 5 different chromosomes in the bovi- i ne genome, we have established the genetic distances ) (21) between the 9 breeds. Calculation was based on the ~ two mathematical matrices of NEI (28) and CAVALLI-1 SFORZA (10). Historical research We have studied different historical and commercial’ archives in the two French West Indies islands of, Guadeloupe and Martinique and we have tried to summa- rize numerous specialized books and bibliographical refe- rentes (16, 20, 41). Retour au menuRetour au menu STVM-93 RESULTS AND CONCLUSIONS In the B haemoglobin system, where the A allele is a marker of 130s taurus breeds (frequency always higher than 90 % whereas in /~OS indicus it rarely exceeds 50 %), it was noticed (figure 1) that the Brahman frequency (55 %) is closer to the zebu average while the Creole one (71 %) indicates clearly an intermediate value between Bas taurus and ~?OS indicus. In the serum albumin system, where the F allele is also a marker of Bos taurus breeds, it is observed here again (figure 2), an intermediate frequency of 52 % for the Creole breed whereas the Brahman value is closer to the The results obtained from these two systems of hae- moglobin and albumin show evidence for the presence of taurine features in the Creole population of Guadeloupe. Concerning the transferrin system :, - for the B allele, (figure 3) the Creole displays a frequen- cy which is very similar to that of zebu breeds, whereas for the taurine breeds the allele B is completely absent ; - for the F allele, the same phenomenon cari be observed (figure 4) suggesting also the presence of 130s indicus blood in the Creole breed. other zebu breeds. Percent. 0,06 _’ : .’ 0,05 .’ .’ .’ : 0,04 f ,’ .’ : .’ 0,03 .’ : :. ,: 0,02 ,,: : 1 Percent. /l , >>, .̂ ̂ \ :t..<:.o:,..r;.. , 1 1.00 030 0,60 0,40 0,20 0.00 . . . . . . . . . . . . . . . . . . . . . . . . ..A 0 HBI3 type B n HBB type A F J B N’D CG SZ KZ F J B N’D CG SZ KZ BZ SM BE Breeds Figure 3 :Transferrin B type polymorphism : Allele frequencies (in percen- tage) in different cattle breeds (seefigure 1) (nd = not determined). The Creole frequency is very similar to those of zebu breeds, wherens this allele is completeh absent in the taurine breeds. (Data sources : CIRAD- EMVT, CRTA, ILRAD, AFRUABRO) Figure 1 : Haemoglobin B type polymorphism : Allele frequencies (in per- centage) in different cattle breeds : F = Friesian, J = Jersey, B = Baoule, N’D = N’Dama, CG = Creole Guadeloupe, SZ = West African Sudan Zebu, KZ = East African Kapiti Zebu, BZ = East African Boran Zebu, BM = Brahman Martinique. The frequency of the A allele which is a taurine marker indicates in the Creole of Guadeloupe, an intermediate value (71 %) between Bas taurus and Bos indicus, whereas the Brahman frequency (55 %) is closer to the zebu average. (Data sources : CIRAD-EMVT, INRA, ILRAD, AFRUABRO) Percent. a’ 0,50 : : : 0,40 .. .’ _’ I i : 0,30 .. ) _ ; : : 0,20 .- . : : :.. . . 0,lO .. , Percent. 1,20 :’ 0.60 0,oo F J B N’D CG SZ KZ BZ BM Breeds 0 ALB type S 1 HALBtype F j 0,oo F J B N’D CG SZ KZ BZ BM Breeds Figure 2 : Albumin type polymorphism : Allele frequencies (in percentage) in dtjferent cattle breeds (see figure 1). The frequency of the F allele which is also a taurine marker indicates in the Creole of Guadeloupe, an intermediate value (55 %) between Bos taurus and Bos indicus, whereas the Brahman frequency is 12 % (Data sources : CIRAD-EMVT, INRA, ILRAD, AFRUABRO) Figure 4 : Transferrin F type polymorphisrn : Allele frequencies (in per- centage) in dtrerent cattle breeds (seejlgure 1) (nd = not determined). The Creole frequency irrdicates an intennediate value between Bos indicus and Bos taurus breeds where this allele is absent. (Data sources : CIRAD- EMVT CRTA. ILRAD, AFRUABRO) 285 Retour au menuRetour au menu J.C. Maillard S.J. Kemp M. Naves C. Palin C. Demangel A. Accipe N. Maillard A. Bensaid In the BoLA Complex: - the frequencies of the KN8 specificity (figure 5) confirm the previous results shown with the transferrin polymor- phisms, that the Creole breed possesses this zebu mar- ker, as expected for the Brahman zebu ; - high frequencies of the KN18 specificity (figure 6) are characteristic of West African Bos taurus populations whereas this specificity has only been found in a very low Gene - : - !i / o.oov ’ ’ ’ ’ ’ ’ ’ ’ ,-- F J 6 N’D CG SZ KZ BZ BM Breeds Figure 5 : Polymorphism of the KN8 specificity in the BoLA Complex : Gene freguencies in different cattle breeds (see figure 1). The Creole frequency of this specifkity is closer to those of Bos indicus breeds including Bruhman. (Data sources : CIRAD-EMVT, ILRAD) Gene Frequencies F J B N’D CG SZ KZ BZ BM Breeds Figure 6 : Polymorphism of the KN18 specificity in the BoLA Complex: Gene frequencies in dtflerent cnttle breeds (see figure 1). The Creole frequency of this specificity is closer to those of the 2 African Bos taurus breeds : N’Damn and Bnoule, indicnting its Africnn taurine ori- gin. Indeed, this KN18 antigen is specific to African taurine being nlmost absent in European taurine breeds. The frequency of’the Brahmnn populo- tion is normnlly closer to those of other Bos indicus breeds. (Data sources : CIRAD-EMVT, ILRAD) level in cattle from Northern Europe. For this reason, a KN18 frequency of 15 % in the Creole population is highly significative in determining the partial West African 90s taurus origin of the Creole breed. This result strongly sug- gests that Creole cattle have acquired their taurine fea- tures not only from European Bos taurus but also from African Bos taurus . For the gamma S crystallin gene polymorphism, it is found (figure 7) that the allele represented by the 128 bp fragment is monomorphic at 100 % in the Creole popula- tion. The most similar frequency of this allele is encounte- red in the African N’Dama (85 %). This result confirms the previous hypothesis obtained with MHC-BoLA typing, viz. that some of the Creole taurine features have been inheri- ted from an N’Dama ancestor. The two dendrograms obtained by the calculations of genetic distance indicate clearly (figure 8) the intermedia- te position of the Creole, breed of Guadeloupe between the N’Dama Bos faurus breed of West Africa and two zebu breeds, the Sudan zebu of West Africa and the Brahman. In the NEI dendrogram the Creole is closer to the African taurine group and far from the European tauri- ne breeds. In the CAVALLI-SFORZA dendrogram the Creole is closer to the zebu group but the N’Dama remains the nearest taurine breed. This slight difference could be explained by the existence of a close equilibrium between Bos taurus and Bos indicus types. Regarding the historical approach, evidence have been accumulated suggesting the following *chronology of the establishment of cattle in the French West Indies. When Christopher Columbus discovered the Caribbean islands in 1492, there was no domestic livestock. i,20 0,60 F N’D CG 5 10 10 SZ BZ BM Breeds 5 5 9 Nb. Of mImals Figure 7 : G/C Bi-Allelic polymorphism of the Gamma S Crystctllin gene in different cattle breeds (seefigure 1). The allele represented by a 128 bp fragment is monomorphic ut 100 % in the Creole population and the most similnr frequency of this allele is the one of the African N’Dnma with 85 %. This indicntes once agnin the African Bos taurus N’Dnmn origin of the Creole crossbred. (Data sources : CIRAD-EMVT, ILRAD) 286 Retour au menuRetour au menu STVM-93 T Z 1 T Z KZ - BZ - CAVALLI-SFORZA Figure 8 : Dendrograms of genetic distance are obtained by using the two different mathematical matrices of NEI and CAVALLI-SFORZA in difSe- rent cattle breeds (see figure 1). It cari be seen clearly in the two dendrograms the intermediate position of the Creole breed of Guadeloupe between the N’Dama Bas taurus breed of West Africa and two zebu breeds, the West African zebu and the BI-ahman In the NEI dendrogram the Creole is closer to the African taurirle groap and far from the European taurine breeds. In the CAVALLI-SFORZA den- drogram the Creole is closer to the zebu group but the N’dama rernains the nearest taurine breed. This slight difference could be explained by the existence of a close equilibrium between Bos taurus and Bos indicus types. All during the colonization period from the XVlth to the XVlllth Century, the cattle which populated these islands were imported from Europe, mainly from Spain and Portugal, but a few from France. At the same time, African cattle were probably also imported from the Spanish, Portuguese and French colonial establishments of Africa, which were located essentially all along the Guinea Gulf Coast (map 1). These dwarf, humpless and shorthorn Bas taurus cattle have been established for 7,000 years (13) in this area infested by the tick Amblyomma variegatum. It was well adapted to the tropi- cal environment and was resistant to certain tropical diseases. In this way it is possible that these cattle could be responsible for the introduction of Amblyomma varie- gatum into the Caribbean islands, since the XVlth centu- ry. Its survival during some weeks of shipping was proba- bly possible by completing its development cycle on different hosts during the journey. Arriving in the tropical environment of the Caribbean islands, this tick was able to acclimatize. Map 1 : Map of .4frica showing the foci of origin and tirne of subse- quent spread in indigenous breeds of &rican cattle. Data are based on PAYNE (1964) and EPSTEIN (1971). The distribution area of .4fricarz Bos taurus either longhorn or shorthortl lies ail along the Guinea Gulf Coast and is included in the distribution area of the tick Amblyomma variegatum. The Spanish, Portuguese and French colonial establish- ments were mainly based in these areas between the South of Senegal and Angola. This tick could have existed in small numbers, without visible pathologie consequences on cattle, before 1828 when its introduction is presumed to have occurred with zebu cattle of Senegal. These cattle of African origin might have resisted diseases associated or with trans- mitted by Amblyomma variegatum, whereas the cattle of European origin might have disappeared progressi- vely. During the XIXth Century, African cattle were imported again : mainly zebus from Senegal to improve the pheno- typic aspects necessary for cart traction in sugar cane cultivation, and pure or crossbred N’Dama cattle from the Gambia (24). This African zebu al,so originated from an area infested with Amblyomma variegatum, and was accustomed to the environmental conditions. It was crossbred with the taurine cattle of African origin (such as the Senepol breed of the Virgin Islands which is a cross- bred population between 2 60s taurus breeds: African N’Dama of Senegal and European Red Poll). The hetero- sis effect could improve the resistance phenomenon in the areas infested by Amblyomma variegatum where the constant parasitic pressure maintained this genetic pre- disposition. 287 Retour au menuRetour au menu J.C. Maillard S.J. Kemp M. Naves C. Palin C. Demangel A. Accipe N. Maillard A. Bensaid All during the XXth Century, the African zebu type was gradually replaced by Indian zebu breeds imported since, from the French establishments of India and from Venezuela. At the present time, this crossbreeding is continuing with Brahman zebu selected in the USA. Also, different attempts at crossbreeding with European breeds for zootechnical improvements were severe failures because of disease. At present, have been studied 5 distinct polymorphie loti situated in 5 distinct chromosomes out of the 26 autoso- mal chromosomes constituting the bovine genome. It is therefore impossible to conclude with certainty on the exact phylogeny of the French West Indies cattle popu- lations. Contribution of Spanish and Portuguese cattle to the taurine features of the Creole breed needs to be assessed because these cattle are the ancestors of the Criollo Bas taurus breed widely distributed in South America and in the Spanish Caribbean islands. Origin and genetic characteristics of European breeds have been recently studied in relation to Indian and African cattle (23, 24)). These studies performed by using mole- cular techniques have revealed new molecular markers, one of them associated with the Y chromosome, allo- wing to distinguish Bas taurus from i3o.s indicus geno- types. In the light of these results, the authors plan to further investigate the genetics of the French West Indian cattle by including Spanish and Portuguese breeds in our pre- sent panel. The rationale of these studies is to define gene pools in different breeds known to be resistant or susceptible to diseases in order to preserve these gene pools in future breeding programs. The authors also think that it could be very interesting and useful to pursue their historical investigations by studies of other archives in several countries. These could be the formerly colonized countries like Trinidad, St Domingo, Cuba and Puerto Rico in the Caribbean, and the formerly colonizing countries like Spain, Portugal and France. ACKNOWLEDGMENTS This work is financially supported by the European Economie Communities (TS3-CT91-0012) and the department of Elevage et médecine vétérinaire of CIRAD. We thank Drs R. QUEVAL and G. DUVALLET (CRTA Bobo-Dioulasso, Burkina Faso), Dr. A. TEALE (ILRAD, Nairobi, Kenya), Dr. R.L SPOONER (ABRO Edinburgh, Scotland), Dr. H. LEVEZIEL (INRA, Jouy-en-Josas, France), Drs D. BRADLEY and D. MACHUGH (University of Dublin, Ireland), Dr. P. ZARAGOZA (University of Saragossa, Spain), for their cooperation in providing samples, reagents or data. 288 REFERENCES 1. ADAMS (T.E.), BRANDON (M.R.). Genetic aspects of disease resistan- ce in cattle. In : BUTLER (J.E.), Ed. The Ruminant system. New York, London, Plenum Press, 1981. P. 451.473. 2. AMORENA (B.), STONE (W.H.). Bovine lymphocyte antigens (BoLA) : a serologic, genetic and histocompatibility analysis. Tiss~e Antigens, 1982, 16(3):212-225. 3. ASHTON (G.C.), LAMPKIN (G.H.). 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CALDWELL (J.). Polymorphism of BoLA system. T&ue Antigens, 1979, 13 : 319-326. 10. CAVALLI-SFORZA (L.L.), EDWARDS (A.W.F.). Phylogenetic ana- lysis: Models and Estimation Procedures. Evol., 1967,121: 550-570. 11. Cowdriosis and dermatophilosis of livestock in the Caribbean region. Proceedings of the CARDI-CTA Seminar, held in St John, Antigua, 12-14 Nov. 1990. 12. DUMAS (R.), LHOSTE (P.), CHABEUF (N.), BLANCOU (J.). Note sur la sensibilité heréditaire des bovins à la streptothricose. Revue Élev. Méd. vét. Pays trop., 1971,24 : 349-353. 13. EPSTEIN (H.). The origin of domestic animais of Africa. New York, Africana Publishing Corp., 1971. 14. Fifth International BoLA Workshop Meeting, held in Aug. 1992. Interlaken (Suisse). Anim. Genetics, Special Issue (in press). 15. GAHNE (B.), JUNEJA (R.K.), GROLMUS (J.). Horizontal polyacryla- mide gradient gel electrophoresis for the simultaneous phenotyping of transferrin, albumin and post albumin in the blood plasma of cattle. Anim. Blood Grps. 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The resistance to dermatophilosis of Dinka cattle breed, Dinka crossbred and Boran, Friesian, Jersey, Sahiwal crossbreds. Ann. Rech. vet., 1987,lS : 107-109. 23. LOFTUS (R.), MacHUGH (D.), BRADLEY (D.), SHARP (P.), CUN- NINGHAM (P.). Mitochondrial genetic distances among European, African and Indian cattle. In : UILENBERG (G.), HAMERS (R.), Eds. Resistance or Tolerance of Animals to Disease and Veterinary Epidemiology and Diagnostic Methods. Proceedings of EEC contractant Workshops, Rethymno (Crete), 2-6 nov. 1992. Maisons-Alfort, CIRAD-EMVT, 1993. P. 72. 24. MacHUGH (D.), BRADLEY (D.), LOFTUS (R.), MEGHAN (C.), SHARP (P.), CUNNINGHAM (P). Molecular biogeography of West African cattle breeds. In : UILENBERG (G.), HAMERS (R.), Eds. Resistance or Tolerance of Animais to Disease and Veterinary Euidemiologv and Diagnostic Methods. Proceedings of EEC contractant Workshops,%ethymno-(Crete), 2-6 nov, 1992. M&ons-Alfort, CIRAD- EMVT, 1993. P. 17. 25. MAILLARD (JC.), KEMP (S.J.), LEVEZIEL (H.), TEALE (A.J.), QUEVAL (R.). Le complexe majeur d’histocompatibilité de bovins ouest-africains. Typages d’antigenes lymphocytaires (BoLA) de taurins Baoulé (Bas tanrus) et de, zébus soudaniens (Bas indicus) du Burkina Faso (Af. Occid.). Revue Elev. Méd. vét. Pays trop., 1989, 42 (2) : 275. 281. 26. MAILLARD (J.C.), PALIN (C.), TRAP (I.), BENSAID (A.). An attempt to identify genetic markers of resistance or susceptibility to derma- tophilosis in the zebu Brahman population of Martinique. Revue Elev. M&l. véf. Pays trop., 1993,46 (l-2) : 291-295. 27. MAULE (J.P.) The Cattle of the Tropics. Univ. of Edinburgh, CTVM. Melksham, Wilts, Eds Redwood Press Ltd, 1990. 225 p, 28. NE1 (M.). Genetic distance between populations, An?. Nnturnlisr, 1972, 106:283-292. 29. OPPONG (E.N.W.). Epizootiology of dermatophilosis infection in catt- le in the Accra plains of Ghana. In : LLYOD (D.H.), SELLERS (K.C). Eds. Dermatophilus Infection in Animals and Man. London. Academic Press. 1976. P. 17-32. 30. OSTERHOF (D.R.). Haemoglobin types in African cattle. .Z. Stll. Afi-. Vet. A~S., 1975,46 (2) : 185-189. 3 1. PETIT (J.P.). Haemoglobin polymorphism studies in West African tr) - panotolerant taurine breeds. Zn : ISAG Meeting, Dublin. Ireland, 12-l 7 Juil. 1976. 32. PHILLIPS (R.W.). World distribution of the major types of cattle. J. Hered, 1961, 52 : 207-213. 33. QUEVAL (R.). Genetic markers of West ‘African cattle breeds. Zrz : Proceedings of a Workshop on Trypanotolerance and Animal Production; held 10-14 May 1982, Avetonou, Togo. Eschborn, GTZ, 1982. P. 207- 216. 34. QUEVAL (R.). Polymorphisme de la transferrine chez les bovins trypa- nosensibles et trypanorésistants de l’Afrique de l’Ouest. Répartition et fré-~ quence de leurs allèles. Revrrr Élev. Méd. vét. Pays trop., 1982, 35 (4) : 373.380. 35. QUEVAL (R.), PETIT (J.P.). Polymorphisme biochimique de l’hémo- globine de populations bovines trypanosensibles,et trypanotolérantes et de leurs croisements dans l’Ouest africain. Revue Elev. Méd. vét. Pqs frop., 1982, 35.(2) : 137.146. 36. QUEVAL (R.), BAMBARA (L.). Polymorphisme de l’albumine dans la race Baoulé et une population de zébus de type soudanien. Revue Elev. ,!4&/. vét. Pays trop., 1984, 37 (N” spécial) : 288-296. 37. SPOONER (R.L.). Genetics of resistance to disease in domestic animals. In : UILENBERG (G.), HAMERS (R.), Eds. Resistance or’ Tolerance of Animals to Disease and Veterinary Epidemiology and Diagnostic Methods. Proceedings of EEC contractant Workshops, Rethymno (Crete), 2-6 nov. 1992. Maisons-Alfort, CIRAD-EMVT, 1993. P.I.5. 38. SPOONER (R.L.), OLIVIER (R.A.). Albumin polymorphism in British cattle. Anim. Prod., 1969,ll : 59-63. 39. SPOONER (R.L.), LEVEZIEL (H.), GROSCLAUDE (F.), OLIVIER (R.A.), VAIMAN (M.). Evidence for a possible major histocompatibility complex (BoLA) in cattle. .Z. Zmmunogen., 1978, 5 :335-346. 40. STEAR (M.J.), BROWN (SC.), DIMMOCK (C.K.). DUFTY (J.H.), HETZEL (D.J.S.), MACKIE (J.T.), NICHOLAS (F.W.), TIERNEY (T.J.), WETHERALL (J.D.). Breed differences in the’frequency of bovine lym phocyte antigens. Exp. C/irt. In?ntunoger?et.,l987. 4 : 27-36. 41. TAILLEMITE (E.). Inventaire de la correspondance à l’arrivée des gou- vernements de Martinique. Paris, SEVPEN, Séries C8A, 197 1. 42. TEALE (A.J.), KEMP (S.J). BoLA typing applications in the Gambia. 111 : Abstracts of African Trypanotolerant Livestock Network Meeting, Nairobi, Kenya, 1987. 43. UILENBERG (G.), BARRÉ (N.), CAMUS (E.), BURRIDGE (M.J.), GARRIS (GI.). Heartwater in the Caribbean. In : RIEMANN (H.P.), BURRIDGE (M.J.), Eds. Impact of livestock diseases on livestock pro- duction in the tropics. Amsterdam. Elsevier Sciences Publishers, 1984. P. 255-268. -14. WAKELIN (D.). Genetic control of susceptibility and resistance to parasitic infection. :lrh.. Pnr-crsitol. 1978. 16 : 2 19-308. 289 Retour au menuRetour au menu J.C. Maillard S.J. Kemp M. Naves C. Palin C. Demangel A. Accipe N. Maillard A. Bensaid MAILLARD (J.C.), KEMP (S.J.), NAVES (M.), PALIN (C.), DEMANGEL (C.), ACCIPE (A.), MAILLARD (N.), BENSAID (A.). An attempt to correlate cattle breed origins and diseases associated with or trans,mitted by the tick Amblyommn varie@um in French West Indies. Revue Elev. Méd. vét. Puys trop., 1993,46 (l-2) : 283-290 By using biological data and historical research, we have tried to explain the difference hetween resistance and susceptibility to the diseases transmitted (cowdriosis) or associated (dermatophilosis) with the tick Amblyomma variegatum, in two cattle breeds of the French West Indies: the Creole crossbred cattle of Guadeloupe and the Brahman zebu cattle of Martinique. Have been studied the polymor- phisms of 5 independent genetic systems (erythrocytic haemoglobin, serum albumin and transferrin, the class 1 region of the BoLA com- plex and the gamma S crystallin gene) in different breeds comprising Bas taurus cattle of Europe and Africa, Bos indicus of West and East Africa, as well as the Brahman of Martinique and the Creole cross- bred of Guadeloupe. By comparing the different allele frequencies of these 5 non related polymorphie loti and by using the two different mathematical matrices of NE1 and of CAVALLI-SFORZA, have been estahlished the genetic distances hetween these breeds. It appears clearly that the Creole cattle of Guadeloupe are in an intermediate position between the Bos taurus N’Dama breed of West Africa and two Bos indicus zebu breeds, namely the West African Sudan zebu and the Brahman. Thanks to studies of different archives in the Caribbean and in Europe, historical evidence have been accumulated on the geographical origins and on the chronology of the establish- ment of Creole and Brahman cattle in the French West Indies. The high resistance of the Creole cattle of Guadeloupe to diseases associa- ted with or transmitted by the “Senegalese” tick Amblyomma variega- tum seems to he due to the inheritance of a pool of genes from West African cattle and more particularly from the N’Dama hreed. Indeed, the tick AmbZyomma variegatum, endemic in all West Africa, was introduced in the Caribhean with West African cattle. Most certainly, this tick maintained a parasitic pressure, hence the innate capability of the Creole cattle to naturally control these diseases. Key words : Cattle - Creole cattle N’Dama cattle Brahman zebu cattle Sudan zebu cattle Heartwater Dermatophilosis - Tick - Amblyomma varie- gntum - Disease resistance - French West Indies - Guadeloupe - Martinique. MAILLARD (J.C.), KEMP, (S.J.), NAVES (M.), PALIN (C.), DEMANGEL (C.), ACCIPE (A.), MAILLARD (N.), BENSAID (A.). Intento de correlacion entre las razas bovinas y las enfermedades relacio-; nadas o transmitidas por,la garrapata Amblyommn vaviegatum en las Antillas francesas. Revue Eh. Méd. vét. Pays trop., 1993, 46 (l-2) : 283-’ 290 Mediante el uso de datos biologicos e historicos, se trata de explicar la; diferencia entre la resistencia y la susceptibilidad a las enfermedades transmitidas (por ejemplo la cowdriosis) o asociadas (por ejemplo la dermatofïlosis) con el acaro Amblyomma variegutum, en dos razas de ganado de las Antillas Francesas : cruce autoctono (Criollo) de Guadalupe y ganado Brahman de Martinica. Se estudiaron Los poli- morfismos de cinco sistemas genéticos independientes (hemoglobina eritrocitica, albumina sérica y transferrina, complejo de clase 1 de BoLA y gen cristalino gama S),,en diferentes razas de ganado Bas; taurus europeo y Bos indicus de Africa del Este y del Oeste, incluyen- do el cruce autoctono (Criollo) de Guadalupe y el ganado Brahman de Martinica. Las distancias genéticas de estas razas, se establecieron mediante la comparacion de las frecuencias alélicas de estos 5 Ioci polimorficos e independientes y el uso de dos matrices matematicas diferentes, de NE1 y CAVALLI-SFORZA. Parece claro que el ganado Criollo de Guadalupe se encuentra en una position intermedia entre el Bos tuurus N’Dama de Africa del Oeste y dos razas cebuinas de Bos indicus, el cebu Sudanés de Africa del Oeste y el Brahman. Gracias a 10s estudios de diferentes archives, tanto en el Caribe como en Europa, logramos acumular la evidencia historica sobre 10s origenes geograficos y cronologicos del estahlecimiento del ganado Criollo y Brahman en las Antillas Francesas. La alta resistencia del ganado Criollo de Guadalupe a las enfermedades asociadas o transmitidas por la garrapata “senegalesa” Amblyomma variegatum, parece ser debida a la carga hereditaria de un “pool” de genes de ganado de Africa del Oeste y particularmente de la raza N’Dama. De hechoi Amblyomma vuriegutum, endémica en Africa del Oeste, fue introduci- da en el Caribe junto con el ganado del oeste africano. Aparentemente, este acaro ha mantenido una presion parasitaria suficiente para la conservation de la capacidad natural del ganado Criollo para el control de este tipo de enfermedades. Palabras claves : Bovino - Bovino Criollo - Bovino N’Dama - Cebu Brahman - Cebti Sudanés - Cowdriosis - Dermatofilosis - Garrapata - Amblyomma variegntum - Resistancia a las enfermedades - Antillas fran- cesas - Guadalupe - (La) Martinica. 290 Retour au menuRetour au menu work_7inntoilrvaz5lc4exys4ckesu ---- 19 Journal of Intercollegiate Sport, 2012, 5, 19-21 © 2012 Human Kinetics, Inc. Michael Oriard on NCAA Academic Reform: Academics Over Dollars Kenneth L. Shropshire University of Pennsylvania The purpose of this paper is to provide a response to Michael Oriard’s keynote address. The paper highlights the link between monies generated through intercol- legiate athletics and calls for academic reforms. There is also need for examination of how increased participant diversity coincided and influenced these dynamics—a connection frequently overlooked. Professor Oriard’s (2012) presentation provides us all with a reminder of the priori- ties in collegiate sports absent from the conversations delivered most recently by American public intellectuals: academics over dollars. He also makes clear that the most prominent recent pieces by Taylor Branch in The Atlantic (2011) and Joe Nocera in the New York Times Magazine (2011) represent the works of a modern- day Christopher Columbus; they were not the first to find the issues, but they have certainly garnered them broader attention. The academic-reform and compensation issues were with us even before the Knight Commission of the past few decades or even the Carnegie Commission in 1929 (Savage, 1929). Oriard’s paper (2012) provides an impressive time line of the history of the National Collegiate Athletic Association (NCAA) and the academic-reform issue. He takes us back to the Teddy Roosevelt trope with college presidents convening to address the sports safety issue of the day—not steroids, but deaths due to the violent nature of the game. He further takes us back to historic crew events featur- ing compensation and “tramp” athletes. What Oriard leaves out is the proximity in time to the creation of the modern Olympiad by Baron Pierre de Coubertin.1 I have always wondered if there was any connection between the two events. Were there any conversations between the originators? What is clear, intended or not, is that the Olympics and the NCAA begin in the same era, and they both evolve as huge enterprises in which labor participates without being compensated in a traditional manner. Labor participates for free because of a mythically created concept of amateurism. Why is amateurism seemingly the fulcrum of all reform issues? How did we get into this mess? It is an understanding of that foundational amateurism background that allows us to move to the real issues Oriard (2012) is focusing us upon and away from the popular focus of the day: money. I advise those interested in the most Shropshire is with the Wharton School, University of Pennsylvania, Philadelphia, PA. 20 Shropshire in-depth analysis to read David C. Young’s The Ancient Myth of Greek Amateur Athletics (1985). He clearly conveys amateurism is both a word and a concept that did not even exist for the ancient Greeks. He points us squarely to Victorian Eng- land and then later to the modern Olympiad, which bumps up against the creation of organized collegiate sports in the United States. The short answer is there is no glamorous history of amateurism. There is certainly, for many, a philosophical basis for the current professional/amateur dichotomy, but looking back, we should also at least contemplate the economic foundations of amateurism: a sporting event or any activity with free labor is likely to be more profitable for the organizers than one for which the labor is paid. But I contend, and as Oriard highlights, this money issue is much less important for society than the issues related to the quality of education received by student athletes. Oriard notes that when we think about academic reform, we are thinking pri- marily about basketball and football. I agree, and I also similarly think, that blended with that thought process, we must reflect on race and other diversity issues. Oriard (2012) alludes, but does not state explicitly, that college sport was predominantly conceived for able-bodied White men. What would we learn from a fully integrated historical discussion of the path of reform incorporating people of color, persons with disabilities, and women? I am not sure. But if we do not take that approach at every juncture when we review reform issues, we risk running afoul of that adage regarding repeating history. Is there a diversity trail one should follow when con- templating academic reform issues? Do we unconsciously insert any biases into our thinking due to the composition of student athletes in a given era? Oriard (2012) does examine to an extent the racial implications in the later years. Deeper exploration should definitely take place regarding the impact of increased diversity on academic performance. I suggest this, not so much so that we can find a culprit on which to place the blame for academic decline, but rather I do so more to examine society’s poor record of education in these communities and contemplate the sad state of educational inequity simply becomes incorporated into the frame of college sport, where such diversity has not always existed. The other issue that I find curious—related to money again—is that the increased revenues in sport have come with increased diversity. There is no real reason to find that one has driven the other. But what is curious is the focus on money in public discourse over academic performance. This relates squarely to my previ- ous point. Is there a diversity connection that we should contemplate more deeply? There have certainly been times when the academic side dominated. As Oriard (2012) highlights, discussions of initial eligibility rules were almost full focused on the academic side, with money rarely raised in the debates of past decades. The challenge, as Oriard (2012) raises, is finding the academic reform “fix.” Even amongst those who agree that there is a need to reform collegiate sports so a better academic deliverable is produced, there is no agreement on how to accomplish this end. Unfortunately, and not surprisingly, neither his paper nor my response provides us with the definitive answer. As in the past, money is a distraction. It is a sexier topic. If granted Oriard’s (2012) “system restore” on this academic performance issue, what would we do differently? The Atlantic and the New York Times Maga- zine are barometers of how the most important issue is not the most focused upon issue. Branch (2011) gives us the free-market solution. Nocera (2011) suggests Academics over Dollars 21 a pay scale. I have mentioned before that the problem has gotten so large, one big solution is not going to be feasible. The White Man’s Burden (Easterly, 2007) focused on solving global issues related to poverty; the argument of finding the multiple successful approaches that are out there and supporting those is the way to go. What are the various academic-support programs around the country that work? Can they be replicated? Can they be tweaked? That is the path we should take, one program at a time. The mind-exploding path of a singular solution, like ending world poverty, is not likely to be found and is, in fact, a distraction on where our resources should be focused. That single focused remedy distraction coupled with the amateurism distraction, doubly deters us from implementing academic reform strategies that work. At a minimum, academic-reform issues, in terms of academic accomplishment, must be separated from issues related to increased compensation, in whatever form. The key to me in any system restore is to restore, maintain, and support the pos- sibility of academic success by the greatest number of student athletes. Note 1. The modern Olympics returned in 1896; the NCAA, as we know it now, is formed in 1905. References Branch, T. (2011, October). The shame of college sports. The Atlantic. Retrieved from http:// www.theatlantic.com/magazine/archive/2011/10/the-shame-of-college-sports/8643/ Easterly, W. (2007). The White man’s burden: Why the West’s efforts to aid the rest have done so much ill and so little good. New York: Penguin. Nocera, J. (2011, December 30). Let’s start paying college athletes. New York Times Maga- zine. Retrieved from http://www.nytimes.com/2012/01/01/magazine/lets-start-paying- collegeathletes.html?pagewanted=all Oriard, M. (2012). NCAA academic reform: History, context, and challenges. Journal of Intercollegiate Sport, 5, 4-18. Savage, H. J. (1929). American college athletics. New York: Carnegie Foundation for the Advancement of Teaching. Young, D. C. (1985). The Olympic myth of Greek amateur athletics. Chicago: Ares. 1. work_7qgontc4pfev3g72otjnh7lz2i ---- Cyberspace 2 This is a preprint of an article whose final and definitive form has been published in Critical Studies in Media Communication Vol. 26, No. 2, June 2009, pp. 104-127. CSMC is available online at http://journalsonline.tandf.co.uk/ Terra Nova 2.0—The New World of MMORPGs David J. Gunkel & Ann Hetzel Gunkel The dominant metaphor used to describe and situate MMORPGs, or massively multiplayer online role playing games (e.g. Ultima Online, EverQuest, World of Warcraft, Second Life, etc.), has been "new world" and "new frontier." By deploying this powerful imagery, game developers, players, the popular media, and academic researchers draw explicit connections between the technology of MMORPGs and the European encounter with the Americas and the western expansion of the United States. Although providing a compelling and often recognizable explanation of the innovations and opportunities of this new technology, the use of this terminology comes with a considerable price, one that had been demonstrated and examined by scholars of the Internet, cyberspace, and virtual reality over a decade ago. This essay explores the impact and significance of the terms "new world" and "frontier" as they have been deployed to explain and describe MMORPGs. Keywords: Computer Games, Ethics, Information Technology, Cultural Studies, New Media MMORPG is not only difficult to pronounce but identifies a technology that is perhaps even more difficult to define. And expanding the acronym, massively multiplayer online role playing game, does not necessarily provide much help. Although these things are routinely called "games," research has demonstrated that they are much more than fun and games. As Edward Castronova (2001) pointed out in his seminal paper "Virtual Worlds: A First-Hand Account of Market and Society on the Cyberian Frontier," a MMORPG, like Sony Online Entertainment's David J. Gunkel is Presidential Teaching Professor of Communication at Northern Illinois University. He is the author of Hacking Cyberspace (Westview, 2001) and Thinking Otherwise: Philosophy, Communication, Technology (Purdue University Press, 2007). Ann Hetzel Gunkel is Director of Cultural Studies at Columbia College Chicago. As Associate Professor of Cultural Studies & Humanities at Columbia, she teaches and publishes in Ethnic Studies, Media Criticism, Feminism, Postmodernism, and Popular Cultural Studies. Correspondence to: David J. Gunkel, Northern Illinois University, DeKalb, IL 60115, USA. Email: dgunkel@niu.edu 1 EverQuest, constitutes a "new world" or "frontier" that is, at least in terms of its social structure and economy, a very real and viable alternative to the terrestrial world we currently inhabit. This conceptualization of the MMORPG as a kind of terra nova, is not something that is unique to Castronova's essay; it is evident in much of the current popular, scholarly, and technical literature on the subject. It appears, for example, in the work of Wagner James Au (2007), the official embedded journalist of Linden Lab's Second Life. Au, who reports on in- world events and activities, publishes his stories on a blog he calls New World Notes, many of which have been collected in the book, The Making of Second Life: Notes from the New World (2008). Likewise the terms "new world" and "frontier" have been employed by "real world" journalists in articles covering MMORPGs, like the Guardian's "Braving a new 'world'" (Pauli, 2006), IT Times's "Is Second Life a brave new world?" (Tebbutt, 2007), The Stanford Daily's "A whole new 'World'" (Ford, 2004), Frankfurter Allgemeine's "World of Warcraft: Die Neue Welt" (Rosenfelder, 2007), and Mother Jones's "Even Better Than the Real Thing: Sweatshop Gamers, Virtual Terrorists, Avatar Porn, and Other Tales from the Digital Frontier" (Gilson, 2007). They are also evident in recent scholarly literature with T. L. Taylor's (2006) Play Between Worlds: Exploring Online Game Culture, the first chapter of which is titled "Finding New Worlds," Cory Ondrejka's (2006) "Finding Common Ground in New Worlds," and Rich Vogel's (2007) "Utlima Online—The Last Great Frontier." The terms are also frequently employed in MMORPG titles, e.g. Atlantis III: Le Nouveau Monde and Frontier 1895, and in entries and comments posted on gaming blogs, e.g. Greg Lastowka's (2003) "New Worlds/Old World" posted on the aptly named weblog Terra Nova, Ninemoon Family's (2007) "Granado Espada: Dispatches from the New World," and Duckling Kwak's (2007) comment on the Second Life blog, "SL is a new frontier; by definition, we are all pioneers." We could go on. If all of this sounds vaguely familiar, there is a good reason for it. It turns out the same discursive maneuvers accompanied the introduction of cyberspace and first generation network applications—chat rooms, LISTSERV, MUDs/MOOs, USENET, BBS, email, and the World Wide Web. As David Gunkel (2001) describes it: immediately after its introduction in 1984, cyberspace was proclaimed the "electronic frontier" and a "new world." Terminology like this currently saturates the technical, theoretical, and popular understandings of cyberspace. From the "console cowboys" of Gibson's Neuromancer to the exciting "new worlds" announced by John Walker of AutoDesk and from the pioneering work of Ivan Sutherland and Tom Furness to John Perry Barlow and Mitch Kapor's Electronic Frontier Foundation, the spirit of frontierism has infused the rhetoric and logic of cyberspace. (p. 14) 2 The examination and critique of this "new world rhetoric" was initiated over a decade ago with Chris Chesher's "Colonizing Virtual Reality" (1993), Mary Fuller and Henry Jenkins's "Nintendo® and New World Travel Writing: A Dialogue" (1995), Ziauddin Sardar's "alt.civilization.faq: Cyberspace as the Darker Side of the West" (1996), and our own "Virtual Geographies: The New Worlds of Cyberspace" (Gunkel and Gunkel, 1997). These publications tracked, investigated, and critiqued the seemingly innocent circulation of this discursive material, demonstrating that the deployment of phrases like "new world" and "electronic frontier" come with a considerable price, one that has potentially devastating consequences. Now this terminology returns and, judging from its popularity, seems to be deployed with little hesitation or even acknowledgement of the critical investigations that were introduced over a decade ago. So what if anything has changed? Or is there something about this particular technology that makes it different this time around, that allows us to redeploy the rhetoric and logic of terra nova without its attendant problems and complications? The following investigates these questions and is divided into three sections. The first considers the terms "new world" and "frontier" as they have been employed to explain and describe MMORPGs and their significance. The second critiques the use of this terminology by investigating three related aspects—the forgetting of history that is part and parcel of both technological innovation and new world adventures, the ethnocentrism implicated in and perpetrated by new world exploration and frontier settlement, and the unfortunate consequences these particular actions have for others. The third and final section examines the effect this critique has on our understanding of the MMORPG and its current and future research. New World Redux The term "new world" refers to and designates the European encounter with the continents of North and South America, which began with Christopher Columbus's initial Caribbean landfall in 1492. Although the exact origin of the phrase is still disputed by historians, it is widely recognized that it was initially popularized in Europe by way of a 1502/03 document attributed to Amerigo Vespucci and titled Mundus Novus (Luzzana, 1992; Zamora, 1993). Ten years later, the Latin form, Terra Nova, appeared as the official title applied to the Americas on Martin Waldseemüller's influential 1513 world map, Carta marina (Johnson, 2006). In the European imagination, this "new world" was understood as an alternative to the "old world." It was situated on the other side of the globe, populated with unfamiliar fauna and flora, and inhabited by other, unknown peoples. As Kirkpatrick Sale (2006) points out, "whatever Europe understood 3 the New World to be—and it was many things, not all clearly assimilated yet—it was a new world, another half of the globe not known before, plainly different from Europe and even the Orient, rich and large and mysterious, a place of new peoples, new vistas, new treasures, new species" (p. 234). "New world," then, names not only a specific geographical location but, perhaps more importantly, designates a powerful and seductive idea, that of a different and uncharted territory open to and available for European exploration, exploitation, and eventual settlement. "Frontier" has a similar lineage. Instead of naming the European encounter with the Atlantic coast of the Americas, however, it identified the western movement of white European settlers across the North American continent. Although the word had been used at the time of this migration to identify the receding boundary of the American West, the idea of the frontier was largely a retroactive construct. "The frontier was," as Ziauddin Sardar (1996) reminds us, "an invented concept which recapitulated an experience that had already past" (p. 18). In fact, the concept of the American "frontier," which is attributed to the historian Frederick Jackson Turner, was introduced and theorized only after the announcement of its closure by the US Census Bureau in 1890. Turner formulated what came to be known as the "frontier hypothesis" (Billington, 1965) in a paper that was read at the ninth annual meeting of the American Historical Association, which was convened in Chicago at the same time as the World Columbian Exhibition's celebration of the 400th anniversary of Columbus's discovery of the New World. "Up to our own day," Turner (1894) writes, "American history has been in a large degree the history of the colonization of the Great West. The existence of an area of free land, its continuous recession, and the advance of American settlement westward, explain American development" (p. 199). Conceptualized in this way, the frontier was not just an arbitrary boundary situated some where west of the Mississippi river; it designated a particular understanding of American history, one which, according to Turner, was directly influenced and informed by the Columbian voyages. "Since the days when the fleet of Columbus sailed into the waters of the New World, America has been another name for opportunity, and the people of the United States have taken their tone from the incessant expansion which has not only been open but has even been forced upon them" (p. 227). According to Turner's hypothesis, then, the frontier was understood as more than a geophysical boundary. It constituted something of a national ideology, one which not only narrated the growth and development of the young nation as it expanded westward but explained the formation of a distinct national character—what some have called the "pioneering spirit." 4 Because the terms "new world" and "frontier" were already more than mere geophysical markers, they were easily applied beyond their original context and scope. As Ray Allen Billington (1965) points out in his reconsideration of Turner's hypothesis, "modern technology has created a whole host of new 'frontiers'" (p. 41). In 1901, for example, Charles Horton Cooley, the progenitor of the sociology of communication, employed the term "new world" to explain the social effects of telecommunications technology. "We understand," Cooley (1962) writes, "nothing rightly unless we perceive the manner in which the revolution in communication has made a new world for us" (p. 65). Echoes of this "new world metaphor," as Gunkel (2001) and Fuller and Jenkins (1995) call it, can also be detected in the early writings addressing cyberspace and the Internet. Cyber-enthusiasts like John Perry Barlow (1990 and 1994) and Timothy Leary (1999), for instance, often mobilized the figure of Columbus and his discovery of the new world as a way to characterize the impact and importance of information and communication technology (ICT). And this "impact" is, at this early stage, characterized as overwhelmingly positive and full of wild optimism. As Nicole Stenger (1992) describes it, "cyberspace, though born of a war technology, opens up a space for collective restoration, and for peace. As screens are dissolving, our future can only take on a luminous dimension! Welcome to the New World" (p. 58). "Frontier" is employed in a similar fashion. In 1996, for example, the conservative think tank The Progress and Freedom Foundation published a white paper that drew explicit connections between the Columbian voyages, the expansion of the American frontier, and the new opportunities introduced by ICTs: "The bioelectric frontier is an appropriate metaphor for what is happening in cyberspace, calling to mind as it does the spirit of invention and discovery that led ancient mariners to explore the world, generations of pioneers to tame the American continent, and, more recently, to man's first explorations of outer space" (Dyson, et al., p. 297). Similar comparisons can be found in both the name and rhetoric of the Electronic Frontier Foundation, which was founded by Mitch Kapor and John Perry Barlow in 1990 to protect the rights of the new cyber-pioneers and homesteaders, Howard Rheingold's The Virtual Community: Homesteading on the Electronic Frontier (1993), and Jeffrey Cooper's "The CyberFrontier and America at the Turn of the 21st Century: Reopening Frederick Jackson Turner's Frontier" (2000). As its title indicates, Cooper not only leverages Turner's "frontier hypothesis" but characterizes cyberspace as reopening the American West. Although he makes brief mention of some of the "costs that settlement imposed in degradation of environment, near- extinction of species and habitat, and displacement of the indigenous populations," Cooper, like most cyber-enthusiasts, provides a rather sanitized and sanguine image: "I suggest that this new 5 cyberfrontier is playing the same role as did 'the West' earlier in American history and, moreover, that it will engender many of the same types of impacts on the nation as a whole" (p. 4). In the discourse of ICT, however, "new world" and "frontier" have always been more than metaphors. This is especially apparent in the considerations of virtual reality technology and computer gaming. "In the rhetoric of the virtual realists," Benjamin Woolley (1992) writes, "this 'nonspace' was not simply a mathematical space nor a fictional metaphor but a new frontier, a very real one that was open to exploration and, ultimately, settlement" (p. 122). According to Woolley, the virtual environments created in the non-space of cyberspace are not to be understood as something like a new frontier; they are, quite literally, a new world—a very real space (albeit one which is entirely virtual) that is open to exploration and colonization. This particular understanding of cyberspace as an another spatial dimension is firmly rooted in William Gibson's Neuromancer (1984), the proto-cyberpunk novel that introduced the neologism, and Neil Stephenson's Snow Crash (1992), which describes something he called "Metaverse," a network accessed, immersive virtual reality environment occupied by and experienced through user controlled avatars. The concept is also evident in video and computer gaming. Although Fuller and Jenkins (1995) trace discursive connections between new world travel writing and the narrative structures of computer gaming, Ziauddin Sardar (1996) finds a more fundamental connection between the two. Many computer games, like "Super Mario Brothers," "Civilization," "Death Gate," "Merchant Colony," and "Big Red Adventure" are little more than updated versions of the great European voyages of discovery. These are not games but worlds, constructed Western Utopias, where all history can be revised and rewritten, all non-Western people forgotten, in the whirl of the spectacle. (p. 17) According to Sardar's argument, computer games not only employ the rhetoric of but actually constitute a new world, and as such provide the space for an exercise of what can only be called "colonization." A similar insight is provided by James Newman (2004), who finds "colonization" to be one of the structuring principles of game play. Typically, videogames create "worlds," "lands" or "environments" for players to explore, traverse, conquer, and even dynamically manipulate and transform in some cases. As we have noted in the discussion of the typical structuring of the videogame into levels or stages, progress through a particular game is frequently presented to the player as progress through the world of the game…videogames may be seen to offer the equivalent of de Certeau's (1984) spatial stories, with gameworlds presenting sites imbued with narrative potential and in which play is 6 at least partly an act of colonization and the enactment of transformations upon the space. (pp. 108-109) A similar lineage and development is present in the evolution of the role-playing game (RPG). It is, for example, evident in MECC's The Oregon Trail. Originally released in 1974, The Oregon Trail was an educational computer game based on and designed to teach school children about the American frontier through first-person role playing. In the game, players assumed the role of a wagon leader with the objective of successfully leading a group of pioneers into the western frontier. The idea of the frontier plays a similar role in the development of multiplayer RPGs. It is, for instance, the organizing principle of TSR's Dungeons and Dragons (D&D). Although a low-tech, tabletop game published in the same year as The Oregon Trail, D&D introduced the basic concepts and structures that inform the text-based, multiplayer online virtual worlds of MUDs/MOOs and their graphical progeny, the MMORPG. According to Gary Gygax, the inventor of the game, D&D plays the role of frontier. Our modern world has few, if any, frontiers. We can no longer escape to the frontier of the West, explore the Darkest Africa, sail to the South Seas. Even Alaska and the Amazon Jungles will soon be lost as wild frontier areas…It is therefore scarcely surprising that a game which directly involves participants in a make-believe world of just such a nature should prove popular. (Gygax, 1979, p. 29; quoted in Fine, 1983, p. 55) Gygax, like Turner (1894), perceived the closing of the geophysical frontier and, like Cooper (2000), situates the RPG as a new frontier—a new world that is open for exploration and adventure. The MMORPG, which is designed and understood as the most recent iteration of RPG technology (Castronova, 2005, p. 9; Lastowka and Hunter, 2006; Taylor, 2006, p. 21), capitalizes on and deploys all these elements. First, MMORPGs are characterized and defined as "new worlds" and "frontiers." This is apparent not only in the marketing literature of games and their coverage in the popular media but also in critical assessments provided by scholars and researchers. As R. V. Kelly (2004) reports: this isn't a game at all, I realized. It's a vast, separate universe with its own rules, constraints, culture, ethos, ethics, economy, politics, and inhabitants. People explore here. They converse. They transact business, form bonds of friendship, swear vows of vengeance, escape from dire circumstances, joke, fight to overcome adversity, and learn here. (p. 9) 7 For Kelly, MMORPGs are not merely an entertaining past-time. They constitute an independent and fully realized world, one which not only offers escape from the restrictions of the "old world" but provides for new and improved opportunities. Engaging with the world of a MMORPG, therefore, is similar to, if not the same as, embarking on a voyage to the New World or the American frontier. "It's the equivalent," Kelly (2004) writes, "of getting on the boat to come to America or piling into the Conestoga wagon to head out west" (p. 63). In this new world, one not only escapes the limitations and trappings of the old world but can begin a new life. The game, like the new world of the Americas and the frontier of the American West, "offers a chance to completely redefine and reinvent yourself" (Kelly, 2004, p. 63). A similar characterization is supplied by Castronova (2005), for whom MMORPGs constitute "synthetic worlds" (p. 4), "an alternative Earth" (p. 6), a "new world" (p. 9), or a "frontier" (p. 8). In fact, it is the latter term that, according to Castronova's (2005) judgment, provides "the simplest answer to the question of what synthetic worlds really are" (p. 8). For Castronova, then, MMORPGs are not analogous or comparable to the frontier; they are quite literally a new territory. This particular formulation is emphasized in a footnote concerning Second Life. "The synthetic world of Second Life," Castronova (2005) writes, "sells server resources to those who want them, and nobody bats an eye when they call it 'land,' for that is what it is. Land. Space. Lebensraum. The New World. Terra Nova" (p. 306). The use of the word "land" by Linden Lab is, on Castronova's account, an entirely appropriate characterization and not simply a clever image or metaphor. This is because Second Life, like other MMORPGs, constitutes another world, a very real world with very real social and economic opportunities for individuals and communities.1 This terra nova, however, is not located somewhere across the Atlantic or on the other side of the Mississippi; it is situated in a computer-generated environment accessed over the Internet. And as with the New World of the Americas and the western frontier of the United States, people have begun migrating to this new land, settling on the frontier, and colonizing this vast, new territory. "Statistics reported in this book," Castronova (2005) writes: will suggest that many people are diving into the new worlds right now, with enthusiasm. Evidently, they find the physical environments crafted by computer game designers much more attractive than Earth. Accordingly, these travelers or colonists have come to maintain a large fraction of their social, economic, and political lives there. (p. 9) 8 Second, understood in this way, MMORPGs participate in the ideology and rhetoric of the European "age of discovery" and American expansionism. This includes, among other things, concepts of individual freedom and egalitarianism that inevitably pull in the direction of utopianism. New worlds, no matter their location or configuration, have always been situated as an alternative to and an improvement over the old world. "During the Renaissance," Carlos Fuentes (1999) writes, "the discovery of America meant, as we have seen, that Europe had found a place for Utopia. Again and again, when the explorers set foot in the new world, they believed that they had regained paradise" (p. 195). And the virtual environments created by various forms of ICT turn out to be the perfect place for relocating and recoding this utopian fantasy. "You might think," Kevin Robins (1995) explains, "of cyberspace as a utopian vision for postmodern times. Utopia is nowhere (outopia) and, at the same time, it is also somewhere good (eutopia). Cyberspace is projected as the same kind of 'nowhere-somewhere'" (p. 135). Despite the fact that both Gibson's and Stephenson's cyberpunk science fiction present distinctly dystopian visions, the first generation of writings on and about cyberspace were unapologetically idealistic and utopian (Sardar, 1996; Gunkel and Gunkel, 1997). This utopian strain, as Gunkel (2001) has pointed out, is not something that is limited to recent innovations in ICT but is part and parcel of virtually every innovation in communication technology (p. 43). Electric telegraphy, for example, was powered by an ideology that deployed the rhetoric of and made explicit connections to Christian eschatology (Carey, 1989, p. 17). Radio had been, at least during the first decades of its dissemination, promoted as a kind of deus ex machina that would repair the deep wounds of industrialized modernity (Spinelli, 1996). Television, as Marshall McLuhan (1995) famously argued, abolished the physical limitations of terrestrial distance, reducing the effective size of the planet to a "global village" (p. 5). And the Internet, as Julian Dibbell (2006) describes it, was supposed to have created a "commerical utopia"—"a realm of atomless digital products traded in frictionless digital environments for paperless digital cash" (p. 23). The new worlds of MMORPGs are no exception—utopian ideas and rhetoric saturate the contemporary discussions, marketing campaigns, and debates. Second Life, for example, is routinely described in terms that evoke such optimism. "Our goal with Second Life," Philip Rosedale, the founder and CEO of Linden Lab, has stated, "is to make it better than real life in a lot of ways" (CBS News, 2006). Even in those circumstances where the assessment is more measured, utopianism is still the operative category. Grey Drane (2007), for instance, is not ready to call Second Life utopia, but he still finds it involved with utopian ideas. "OK, I'm not suggesting that utopia can be achieved in Second Life, but it might be the kind of environment in which you could play around with what the word 'utopia' might actually mean" (p. 1). 9 This utopianism, however, is not something that is limited to the world of Second Life or the popular hype that currently surrounds it. The same is true with other games and their critical assessment. Kelly (2004), for instance, argues that MMORPGs offer alterative worlds that are not just different from but "better than the real world" (p. 9). And in justifying this statement, he mobilizes a frontier mythology that is distinctly American. "A MMORPG, after all, is a completely separate and egalitarian world where energy and resolve determine your fate and where appearance, age, connections, and socioeconomic advantage are all meaningless. In a MMORPG it doesn't matter how young and pretty you are, how svelte you are, what color your skin is, how much money you were born into, how well you did on your SATs, or who you know. The only thing standing between you and success is you" (p. 63). For Kelly, the MMORPG fulfills all the promises of the techno-libertarian idea of utopia—a new world where the limitations of old world traditions and institutions do not matter, and a man (because the rhetoric of this ideology is always masculine) can determine his own life, his own opportunities, and his own success. A similar argument is supplied by Castronova. In his initial paper on the subject of MMORPGs, Castronova (2001) explains the growing popularity of these virtual worlds (VWs) by mobilizing the same mythos: "Unlike Earth, in VWs there is real equality of opportunity, as everybody is born penniless and with the same minimal effectiveness. In a VW, people choose their own abilities, gender, and skin tone instead of having them imposed by accidents of birth. Those who cannot run on Earth can run in a VW. On Earth, reputation sticks to a person; in VWs, an avatar with a bad reputation can be replaced by one who is clean" (p. 15). According to Castronova, the virtual world of a MMORPG provides users with an equal opportunity world, where they are effectively liberated from the inherent baggage of and unfortunate restrictions imposed by terrestrial existence. This is again a reason to be optimistic. "Looking beyond these simple joys of immersive, interactive entertainment, however, it should be stressed that synthetic worlds may eventually make contributions to human well-being that will be judged as extraordinarily significant" (Castronova, 2005, p. 25). In the final analysis, Castronova (2005) goes so far as to risk venturing the "outrageous claim" that "synthetic worlds may save humanity" (p. 278). And if they do not actually achieve what we currently understand by "utopia," they do at least provide the best chance to explore and examine its possibilities. "It may well be the case," Castronova (2005) writes: that no one spends time in worlds constructed as they 'ought' to be; if we build Utopia and no one comes, we need to get serious about revising our notions of Utopia. The point here is that Utopian concepts need to be part of our strategy in making use of this technology. Let's build places that we truly believe are the 10 best possible places to be. The very act of building them is a discussion about the future of humankind. (p. 262) Third, because MMORPGs are understood as new worlds, researchers situate themselves in the position of explorers and their accounts often read like a travel journal, a frontier chronicle, or Columbus's Diario—those writings that Fuller and Jenkins (1995) call "new world travel writing." Frank Schaap (2002), for instance, describes his ethnographic investigation of MUDs and MOOs in terms that evoke new world travels: "The journey is not just about getting to know a strange land and understanding the Other and his culture, it is also, and maybe more importantly, a way to better understand the Self, one's own country and culture" (p. 1). Like Columbus and several generations of European explorers to the new world, Schaap characterizes his research as a voyage to another world, where he confronts the Other and returns home with a new understanding of self and country.2 A similar approach is evident in Kelly's Massively Multiplayer Online Role Playing Games. Kelly (2004) begins his examination with a first- person account of his own adventures in the new world of a MMORPG, and, like many new world adventure tales, he narrates how he is lost and on the verge of death, if not already dead. "Somewhere in the middle of the virtual forest my corpse is rotting away. Its flesh will decay overnight if I don't discover its final resting place, and I'll lose the trinkets that are stored on the cadaver—serious trinkets, important trinkets" (p. 1). And Castronova does something similar. In the "Virtual Worlds" article from 2001, he not only includes entries from his journal but explicitly identifies his own research efforts with that of a new world explorer. In the past, the discovery of new worlds has often been an epochal event for both the new world and the old. The new world typically has a herald, a hapless explorer who has gotten lost and has wandered aimlessly about in strange territory, but has had the wit and good fortune to write down what he has seen, his impressions of the people, and the exciting dangers he has faced, for an audience far away. In similar fashion, I stumbled haplessly into Norrath in April 2001, and then spent four months wandering around there. It took me about six weeks to get my bearings. I began recording data in May. And I assure you, I faced many dangers, and died many, many times, in order to gather impressions and bring them back for you (p. 4). In providing this reflection, Castronova explicitly characterizes his own research efforts in terms that evoke the heroic adventures of the "great" European explorers—Christopher Columbus, Amerigo Vespucci, Walter Raleigh, etc. MMORPGs, like EverQuest, are new, new worlds and, because of this, the researcher plays the role of the hapless explorer who ventures into the 11 unknown, faces unprecedented dangers, and returns home with fantastic tales of exotic peoples, strange lands, and exciting opportunities. The Darker Side of the West Characterizing MMORPGs as a new world or frontier seems innocent enough. In fact, these terms are not without a certain amount of discursive utility, as is immediately evident from their seemingly unrestrained proliferation in the popular press, technical literature, marketing campaigns, scholarly investigations, blogs, etc. By describing MMORPGs in this fashion, one connects this "practical virtual reality" technology, as Castronova (2005, p. 3) calls it, to the history and legacy of European exploration and the westward expansion of the United States, two epoch-defining events that are noteworthy for their socio-political innovations, economic opportunities, and celebrated adventures. At the same time, however, neither term is without considerable controversy and criticism. Although the concept of the "new world" remained relatively unchallenged for several centuries, it gets submitted to significant re-evaluation in the later-half of the twentieth century. As the quincentennial of Columbus's first American landfall approached, scholars and educators, especially in the Americas, engaged in a wholesale reassessment of the Columbian legacy (Brandon, 1986; Fuentes, 1999; Pagden, 1993; Zamora, 1993). The most polemic of these criticisms ventured a fundamentally revised image of the Admiral and subsequent European explorers/colonizers, one in which these events were interpreted not as heroic acts of discovery but as the first steps in what became a violent invasion, bloody conquest, and unfortunate genocide. "The New World," as Carlos Fuentes (1999) argues, "became a nightmare as colonial power spread and its native peoples became the victim of colonialism, deprived of their ancient faith and their ancient lands and forced to accept a new civilization and a new religion. The Renaissance dream of a Christian Utopia in the New World was also destroyed by the harsh realities of colonialism: plunder, enslavement, genocide" (p. 195). Similar criticisms were leveled against the image of the American frontier. Shortly after Turner's death in 1932, a new generation of historians took issue with his "frontier hypothesis," finding, among other things, questionable forms of provincialism, determinism, and ethnocentrism (Billington, 1965, p. 2). Despite these critical insights, however, MMORPG developers, players, and researchers deploy the terms "new world" and "frontier" with little or no evidence of hesitation or critical self-reflection, leaving one to reissue a query initially proposed by Fuller and Jenkins (1995) over a decade ago: "One has to wonder why these heroic metaphors of discovery have been adopted by popularizers of new technologies just as these metaphors are 12 undergoing sustained critique in other areas of culture, a critique that hardly anyone can be unaware of in the year after the quincentennial of Columbus's first American landfall" (p. 59). This lack of consideration is evident, for example, in Kelly's research and the experiences of the gamers he interviewed. "Many of the players I spoke with," Kelly (2004) writes, "mentioned that they owned reprints of the diaries of Christopher Columbus, the ship's logs of Captain Cook, the journals of Lewis and Clark, the travelogues of Marco Polo, or the histories of Magellan, Ibn Battuta, or Zhang He. They were fascinated with exploration. And MMORPG games were the closest they could come to discovering new continents on their own" (p. 72). In reporting this data, Kelly explicitly recognizes a connection between the history and literature of exploration and the experience of MMORPG game play. MMORPGs, on this account, simulate new worlds or uncharted territory, offering players the opportunity to experience the thrill and adventure of discovery. At the same time, however, Kelly's account provides no acknowledgement of the profoundly complicated history that is part and parcel of the age of discovery and that is both recounted and recorded in this literature. This rather selective and arguably superficial reading of history is, however, not without justification. If MMORPG developers, players, and researchers do not explicitly account for the problems and complications that have become historically sedimented in the terms "new world" and "frontier," it is because both computer technology and the concepts of the new world and frontier are presumed to be liberated from the burden of history. Computer technology has often been characterized as radically ahistorical. "New technologies are," Simon Penny (1994) argues, "often heralded by a rhetoric that locates them as futuristic, without history, or at best arising from a scientific-technical lineage quite separate from cultural history" (p. 231). New technology and ICT in particular is often characterized as radically distinct and different from anything that came before, providing for a significant break with tradition that facilitates an easy escape from both cultural context and history. Even though technology is always the product of a specific culture and introduced at a particular time for a particular purpose, the futuristic rhetoric that surrounds technical innovation allows for this context to be set aside, ignored, or simply forgotten. As Ken Hillis (1999) summarizes it, "cyberspace and VR are, respectively, a frontier metaphor and a technology offering both the promise of an escape from history with a capital H, and the encrusted meanings it contains, and an imaginary space whereby to perform, and thereby possibly exorcise or master, difficult real- world historical and material situations" (p. xvii). This tendency to escape from or exorcise history is also one of the integral components of the myth of the new world and the American frontier. "The imagination of Americans after 1800," David Noble (1964) argues: 13 was dominated by the belief that the American West represented a redemptive nature which would provide spiritual salvation for the men who settled upon it. European man, corrupted by civilization, was reborn, made innocent, when he abandoned old world history for new world nature. (p. 419) The new world of the Americas was situated and idealized as a place where Europeans could forget the problems and complications of the old world, exit the burdens imposed upon them by history, and begin anew. Consequently, what allows MMORPG players, developers, and researchers to set aside the complex histories associated with the new world and frontier is the fact that these terms already deploy, validate, and justify a forgetting of history. If the new world was where Europeans came to forget their past and begin anew, MMOPRGs appear to be where one now goes to forget the unfortunate history and legacy of this forgetting. Although the "darker side" of this history appears to have been effectively suppressed by those involved with MMORPGs, their descriptions and characterizations are nevertheless ethnocentric. And to make matters worse, this ethnocentrism is itself a byproduct of the forgetting of history. The concepts of "new world" and "frontier" are not semantically empty or neutral. They have been derived from and are rooted in a distinctly white, European understanding and experience.3 They are, therefore, already involved in a particular set of assumptions and values that are culturally specific and by no means universally accepted or applicable. The characterization of the new world and the frontier as vast open territories, ripe with new economic opportunities to be exploited, and providing the perfect location for potentially utopian communities is a fantasy that is unique to Renaissance Europe and the relatively new nation of the United States. Other populations do not share these values and assumptions nor do they experience frontiers and movement into and through the frontier in the same way. The native peoples of South and North America, for instance, account for the so- called "age of discovery" and the settling of the American West with an entirely different and much less optimistic understanding. This is particularly evident in critical reassessments of the dominant historical narratives as provided by scholars Tzvetan Todorov (1984), Berry Lopez (1992), and Carlos Fuentez (1999), and performance-artists Coco Fusco and Guillermo Gómez- Peña (Fusco, 1995); and efforts to write alternative histories like those introduced by historians Jonathan Hill (1988), Alvin Josephy (1993), and Francis Jennings (1994). Deploying the grand narratives of exploration, colonization, and settlement as if they were somehow beyond reproach and universally applicable has the effect of normalizing a particular culture's experiences and asserting them over and against that of all others. This is not only presumptuous, it is, as Gunkel (2001) points out, the ethnocentric gesture par excellence—one assumes that his/her experience 14 is normative, elevates it to the position of a universal, and imposes it upon others (p. 34). In using the terms "new world" and "frontier," MMORPG developers, players, and researchers, impose a distinctly Euro-American understanding, colonizing both the idea and the technology of the MMORPG.4 This kind of implicit ethnocentrism can, for instance, be found in Castronova's account of migration. Although "migration" sounds considerably less disturbing than "colonization," its formulation is nevertheless dependent upon and informed by ethnocentric bias. Writing in 1998, Michael Vlahos describes the initial migration of people to the "infosphere," another name for the then nascent cyberspaces created and sustained by computer networks, like the Internet (p. 498). "Human migration to the Infosphere," Vlahos (1998) explains: represents an historical shift on several levels of significance. It is a true transhumance—a movement of human society to a new place, much like the colonizing of the New World, while still connected to the old. It is thus a migration away from, as well as toward, the in situ and material patterns of all human relationships to something very different and more complex. This entails a migration from long familiar patterns of culture. Human culture has always adapted to fit new environments, and the change is often as difficult as it is exhilarating. (p. 500) Castronova provides a similar account, when he describes the current migration to MMORPGs as involving a movement of people justified and explained by the promise of better opportunities and experiences. "However we refer to these territories," Castronova (2005) writes the most general causes and effects of any migration into them may not be hard to predict. Human migration is a well-known and fairly well-studied phenomenon. A simplified economic story would say that those doing relative less well in one place face the risks of change and head off to a new place. They stake claims there but retain ties with their former neighbors. If they do well, they stay; if they don't they go back…While this is a happy story in the long run, nonetheless, it is also a story of great change and short-run stress. (p. 11) This account of a potentially significant migration to MMORPG cyberspace, despite what might appear to be a neutral stance, is unfortunately biased and ethnocentric. It privileges the interests and fate of the migrating population, emphasizing their new opportunities, their hardships and stresses, and their connections to the old world they leave behind. What such an account conveniently leaves out is consideration of the effect this mobility has on the indigenous peoples who were historically the unfortunate victims of such movement. Consider, for example, 15 the narrative structure usually employed in the mythology of the American West. The standard story, one told in countless Hollywood westerns, goes like this: At one time a group of brave pioneers left the comforts of home and hearth. They embarked on a long and dangerous journey to a new land west of the Mississippi river. They endured many hardships and had to deal with all kinds of stress. But eventually, through their own hard work and ingenuity, they were successful in domesticating this wild and uncharted territory. This is, no doubt, a good story, and it makes for some compelling and enduring drama. Unfortunately it also effectively excludes consideration of those indigenous peoples that Columbus had originally misidentified as "Indians." Or if there is some consideration, these others are more often than not reduced to one more challenging hardship that needs to be endured and eliminated—what is often called quite pejoratively "those pesky Indians." In organizing the explanation so that it is told from the perspective of the migrating population, those individuals who Castronova calls "travelers" or "colonists," one participates in and perpetuates ethnocentrism.5 Stating this, however, appears to ignore the fact that MMORPGs, like other forms of computer-generated cyberspace, are not inhabited by an indigenous population who would be subject to displacement, enslavement, and colonization. What makes the new, new worlds of the MMORPG different, is that this time around there do not appear to be victims. "I would speculate," Mary Fuller writes: that part of the drive behind the rhetoric of virtual reality as a New World or new frontier is the desire to recreate the Renaissance encounter with America without guilt: this time, if there are others present, they really won't be human (in the case of Nintendo characters), or if they are, they will be other players like ourselves, whose bodies are not jeopardized by the virtual weapons we wield. (Fuller and Jenkins, 1995, p. 59) Understood in this way, computer technology simulates new territories to explore, to conquer, and to settle without the principal problem that has come to be associated with either the European conquest of the Americas or the westward expansion of the United States. Unlike the continents of North and South America, these new worlds are not previously inhabited. "Plenty of humans," Castronova (2007) points out, "lived in the allegedly New World happened upon by Christopher Columbus. Not so with new virtual worlds. On the day of launch, these are truly newly created terrains that no human has yet explored" (p. 63). MMORPGs, then, reengineer or reprogram the concept of the new world, retaining all the heroic aspects of exploration and 16 discovery while stripping away the problems that have historically complicated the picture. As Gunkel (2001) explains it: the terra nova of cyberspace is assumed to be disengaged from and unencumbered by the legacy of European colonialism, because cyberspace is determined to be innocent and guiltless. What distinguishes and differentiates the utopian dreams of cyberspace from that of the new world is that cyberspace, unlike the Americas, is assumed to be victimless. (p. 44) The new worlds of cyberspace are not occupied by others; they are effectively open and empty. They are, therefore, available for frictionless and guilt-free exploration and settlement. Understood in this way, movement into and through MMORPGs is a matter of individual choice, and the decision is ultimately based on what appears to be best for the user. As Castronova (2005) describes it, "those who do well by moving, move; those who do well by staying, stay; and everyone eventually finds the best possible place to be" (p. 11). Although this sounds good, it is insensitive to the very real conditions of others. "Cyberspace," as Sardar (1996) reminds us, "does have real victims" (p. 19). These victims are not situated within the space of the MMORPG world but are those others who cannot, for numerous reasons, participate. Although the encounter with MMORPGs offers "everyone," as Castronova claims, the opportunity to find "the best possible place to be," there are others, the majority of humanity in fact, who do not have a choice in the matter. That is, the place where they find themselves is not something that they actively select or have the ability to change. The decision to migrate to a MMORPG or not, which is often presented as if it were simply a matter of personal preference, is a privilege that only a small percentage of the world's people get to consider. As Olu Oguibe (1995) describes it Despite our enthusiastic efforts to redefine reality, to push the frontiers of experience and existence to the very limits, to overcome our own corporeality, to institute a brave new world of connectivities and digital communities, nature and its structures and demands still constitute the concrete contours of reality for the majority of humanity. (p. 3) Access to computer technology and the opportunity to experience the new worlds and open vistas of a MMORPG is something that is only available to a small fraction of the world's population. The majority of humanity, as Oguibe points out, does not have the luxury to question or contemplate the issue. Consequently these statements about migration and individual choice can only be made from a position of relative privilege that remains effectively blind to the fact that others—most others—do not have the option to participate in such a discussion. "Although this 17 virtual exclusion," as Gunkel (2001) calls it, "is admittedly bloodless and seemingly sanitized of the stigma of colonial conquest, it is no less problematic or hegemonic" (p. 45). For the victims of colonial conquest, then, the MMORPG presents something of a double whammy. Not only do the events of new world conquest and frontier settlement conjure up less than pleasant memories for indigenous and aboriginal peoples, but many of these populations are currently situated on the "information have-nots" side of the digital divide. To put it in rather blunt terms, the message is this: Listen, we understand that what we thought to be a new world and frontier didn't go so well for you folks, and we really regret that whole genocide thing. That was clearly a mistake. But we can just forget about all that. This time we're going to get it right. Because this time we have excluded you people from the very beginning. Conclusions When the history of the 21st century comes to be written, it is possible that the first decade of the new millennium will be remembered alongside the years 1492, the year of Columbus's discovery of the New World, and 1894, the year Frederick Jackson Turner introduced the frontier hypothesis. This is because the 2000's are already being promoted as the decade in which new worlds were discovered and a brand new frontier was first opened to migration, exploitation, and settlement. Although this account sounds promising, it has, as we have seen, a number of important consequences. First, using the terms "new world" and "frontier" to characterize MMORPGs clearly have a way of articulating what is really interesting and compelling about this technology. In fact, by using this terminology, one can immediately and intuitively perceive why so many developers, players, and academics understand MMORPGs as much more than fun and games. When described in terms of "new worlds" or "new frontiers," MMORPGs are framed, to use George Lakoff's (2002) word, as vast new territories that are open to exploration, settlement, and exploitation. As Barlow described it back in 1990, "Columbus was probably the last person to behold so much usable and unclaimed real estate (unreal estate)" (p. 37). Understood in this way, MMORPGs are not just another network application or a new form of entertainment but are, as Castronova (2005), Taylor (2006), Kelly (2004) and many others argue, an important socio-cultural development that needs to be taken seriously. These synthetic new worlds, like the New World of the Americas and the frontier of the American West, offer new economic and social opportunities, provide a location for innovative and unheard of adventures, and even support grand utopian experiments and new forms of community. This is 18 understandably hard to resist, and it is difficult to fault the players, developers, and scholars who leverage this powerful rhetoric and historical precedent. At the same time, however, "new world" and "frontier" have what Sardar calls a "darker side," specifically the forgetting of history, the imposition of colonial power and the exercise of ethnocentrism, and the unfortunate exclusion of others. Colonization, violent conquest, and bloody genocide necessarily haunt the use of this terminology and mitigate against its effectiveness and significance. To make matters worse, the current publications, marketing literature, and academic studies surrounding MMORPGs willfully ignore, unconsciously suppress, or conveniently forget these important complications. And they do so despite the fact that a good number of articles and books were published on this exact subject over a decade ago. Consequently, the current crop of texts addressing and promoting MMORPGs not only perform a highly selective and arguably uninformed reading of history but participate in and even perpetrate the very problems they exclude and leave unarticulated. Second, words matter. When all is said and done, the problems we have identified have to do with language. That is, the critical issue concerns not MMORPGs per se but the words that have, for better or worse, been selected by game developers, promoters, players, and academics to describe, characterize, and frame MMORPGs in contemporary discussions, marketing campaigns, and debates. The problem, then, is not with MMORPGs in general or any particular MMORPG but with the use and circulation of the terms "new world" and "new frontier." These words, however, are not immaterial. As Gunkel (2001) explains, "the words that are employed to describe a technological innovation are never mere reports of the state-of-the-art but constitute sites for the production and struggle over significance" (p. 50). Consequently, what MMORPGs are and, perhaps more importantly, what we understand MMORPGs to be, is as much a result of computer programming and game design practices as it is a product of the discursive decisions made by game developers, marketing firms, journalists, gamers, scholars, educators, bloggers, etc. Addressing this difficulty, however, is not simply a matter of finding a better and less controversial terminology. Whether we call MMORPGs new worlds, new frontiers, games, parallel universes, synthetic worlds, or something else we inevitably inherit etymological baggage that we do not necessarily control or even fully comprehend. The goal, then, is not to identify some pure linguistic signifiers that would be unaffected by these complications and issues. Language, any language, is already shaped by the sediment of its own culture and history. This is simultaneously the source of its explanatory power and a significant liability. The best we can do is to remain critically aware of this fact and to understand how the very words we employ to describe technology already shape, influence, and construct what it is we think we are 19 merely describing. This is, as James Carey (1992) explains it, the "dual capacity of symbolic forms: as 'symbols of' they present reality; as 'symbols for' they create the very reality they present" (p. 29). Consequently, the critical issue is to learn to deploy language self-reflectively, knowing how the very words we use to characterize a technological innovation are themselves part of an on-going struggle over the way we understand the technology and frame its significance. Third, there is a way that all of this bends around and facilitates opportunities for critical self-reflection on the current state of game studies. In the inaugural issue of Game Studies, for example, Espen Aarseth (2001) argued in favor of a distinct academic discipline to address computer games. According to his account, games constitute a new and uncharted field of investigation that is exposed to the pressures of colonization. The greatest challenge to computer game studies will no doubt come from within the academic world. Making room for a new field usually means reducing the resources of the existing ones, and the existing fields will also often respond by trying to contain the new area as a subfield. Games are not a kind of cinema, or literature, but colonizing attempts from both these fields have already happened, and no doubt will happen again. (p. 2) For Aarseth, and others who follow his lead (Douglas, 2002; Eskelinen, 2001 and 2004; Pearce, 2004), the nascent field of game studies is rhetorically situated as virgin territory that has endured and will need to struggle against the colonizing forces of the established, old world disciplines. For this reason, his account deploys many of the discursive tropes that are constitutive of and operative in the narratives of new world exploration and conquest. We all enter this field from somewhere else, from anthropology, sociology, narratology, semiotics, film studies, etc., and the political and ideological baggage we bring from our old field inevitably determines and motivates our approaches. And even more importantly, do we stay or do we go back? Do we want a separate field named computer game studies, or do we want to claim the field for our old discipline? (p. 3) In this way, Aarseth situates scholars of computer games in the position of new world explorers. No one, he argues, is indigenous to this new land; we all come from somewhere else. And in coming from these other places, we all carry a certain amount of baggage—assumptions, methods, and practices that come to be imposed on this new territory in order to make sense of it and to domesticate it. Finally like all new world explorers and adventurers, the big question, the question that really matters for each of us, is whether to make our home in this new world or to 20 claim it for our homeland. Elsewhere Aarseth (2004) reiterates this claim, although in this context he leverages frontier imagery: the great stake-claiming race is on, and academics from neighboring fields, such as literature and film studies, are eagerly grasping 'the chance to begin again, in a golden land of opportunity and adventure' (to quote from the ad in Blade Runner). As with any land rush, the respect for local culture and history is minimal, while the belief in one's own tradition, tools and competence is unfailing. Computer game studies is virgin soil, ready to be plotted and plowed by the machineries of cultural and textual studies. (p. 45) Clearly this language and these metaphors are persuasive, seductive, and powerful. At the same time, however, they deploy the problematic mythology and ideology that we identified and critiqued in the discourse of MMORPGs. Consequently the problem is not whether and to what extent other disciplines might come to "colonize" computer games and game studies or whether we resist the onslaught and support what Celia Pearce (2004), who considers herself an "'indigenous' game person," the "further development of an indigenous theory" (p. 1). The problem is that we have already defined and articulated the main problem for game studies in terms that are themselves already questionable and problematic. Finally, one could, with some justification, end by asking the question, "so what's your solution?" Or as Neil Postman (1993) puts it, "anyone who practices the act of cultural criticism must endure being asked, What is the solution to the problems you describe?" (p. 181). This question, although entirely understandable and seemingly informed by good "common sense," is guided by a rather limited understanding of the role, function, and objective of critique—an understanding of instrumental rationality that, like the deployment of the new world and frontier metaphors, might be seen as particularly American given the legacy of Pragmatism. Colloquially the word "critique" is understood as the process of identifying problems and imperfections that then require some kind of reparation. This is the way that Postman understands and deploys "critique" in his book Technopoly. There is, however, a more precise and nuanced definition rooted in the tradition of critical philosophy. As Barbara Johnson (1981) characterizes it, a critique is not simply an examination of a particular system's flaws and imperfections designed to make that system better. Instead: it is an analysis that focuses on the grounds of that system's possibility. The critique reads backwards from what seems natural, obvious, self-evident, or universal, in order to show that these things have their history, their reasons for being the way they are, their effects on what follows from them, and that the starting point is not a given but a construct, usually blind to itself. (p. xv) 21 Understood in this way, critique is not an effort that simply aims to discern problems in order to fix them. There is, of course, nothing inherently wrong with such a practice. Strictly speaking, however, critique involves more. It consists of an examination that seeks to identify and to expose a particular system's fundamental operations and conditions of possibility, demonstrating how what initially appears to be beyond question and entirely obvious does, in fact, possess a complex history that not only influences what proceeds from it but is itself often not recognized as such. This is the case with the terms "new world" and "frontier." Although the use of this rather powerful terminology seems innocent enough, it proceeds from and entails a rich and equally problematic history. This history not only has a considerable cost but entails an amnesic forgetting of the past that effectively blinds us to its influence. The objective of the critique, therefore, is to distinguish and to expose this particular structure, its operations, and its implications. And we do so, it is important to note, not because we oppose MMORPGs, their current use and future development, or the important research that has been undertaken thus far. Our point rather is that the current excitement about these "new worlds" and "new frontiers" needs to be tempered by an understanding of the history, logics, and ideologies that have been mobilized in the process of deploying this very terminology. Notes [1] Technically speaking Second Life is not exactly a MMORPG; then again it is not something entirely different. The FAQ on Linden Lab's (2008) website explains its ambivalent position in the following way: Is Second Life a MMORPG? Yes and no. While the Second Life interface and display are similar to most popular massively multiplayer online role playing games (or MMORPGs), there are two key, unique differences: 1) Creativity: Second Life provides near unlimited freedom to its Residents. This world really is whatever you make it, and your experience is what you want out of it. If you want to hang out with your friends in a garden or nightclub, you can. If you want to go shopping or fight dragons, you can. If you want to start a business, create a game or build a skyscraper you can. It's up to you. 2) Ownership: Instead of paying a monthly subscription fee, Residents can obtain their first Basic account for FREE. Additional Basic accounts cost a one-time flat fee of just $9.95. If you choose to get land to live, work and 22 build on, you pay a monthly lease fee based on the amount of land you have. You also own anything you create—Residents retain IP rights over their in- world creations. There is an ongoing debate over the essential characteristics of games and what is or is not a game (for more on this debate, see Harrigan and Wardrip-Fruin, 2007). And depending on how you look at it and who provides the explanation, Second Life both is and is not a MMORPG. More importantly, however, when a distinction is advanced, the leadership at Linden Lab has explained the difference by mobilizing the figure and rhetoric of terra nova. "I'm not building a game." Philip Rosedale, the CEO of Linden Lab and "founding father" of Second Life told Wired magazine's Daniel Terdiman in 2004. "I'm building a new country" (p. 2). In providing this explanation, however, Rosedale does not so much distinguish Second Life from other MMORPGs as he grounds their point of contact in a common and problematic ideology. [2] This particular narrative trajectory, which is deployed by and manifest in many of the canonical works of Western literature, is one of the fundamental characteristics of what Edward Said (1979) called "Orientalism." Wendy Chun (2003) has traced explicit connections between the concept of Orientalism and the literary constructions of cyberspace, demonstrating how "the narratives of cyberspace, since their literary inception, have depended on Orientalism for their own disorienting orientation" (p. 4). [3] It should not be forgotten that this particular formulation was also gendered. For this reason, the logic and rhetoric of new world exploration and frontier expansion often exhibits complex patterns of gender bias and inequality. "In the past 15 years," Nora Jaffary (2007) explains, "national and regional histories of the Americas in the era of colonization have increasingly incorporated gender analysis, fulfilling in this intriguing context Joan Scott's call for a history of how 'politics constructs gender and gender constructs politics'" (p. 8). As evidence of this, Jaffary (2007, pp. 8-9) provides a litany of recent scholarship, which includes, among other works, Ann Twinam's (1999) investigation of the gendered aspects of social status as articulated in the Spanish colonies of Central and South America, Kathleen Brown's (1996) examination of the construction of political authority in colonial Virginia by the deliberate manipulation of racial and sexual identities, and Karen Anderson's (1991) considerations of indigenous women's subjugation to French men through marriage contracts and, by extension, the subjugation of the territory of North America to the authority of the French Crown. Although it is beyond the scope of the current essay, it would be both interesting and useful to examine the ways these gendered 23 constructions influence and become expressed in the new worlds and frontiers of computer games and MMORPGs. By way of anticipating this subsequent analysis, we note two points of contact. First, the new world of cyberspace is, from the moment of its introduction, already gendered. According to William Gibson, who coined the neologism in his 1984 cyberpunk novel Neuromancer, cyberspace is identified as "the matrix," a term that not only has a nominal association with mathematics but also anticipates the popular vision of immersive virtual reality as exhibited by the Wachowski brother's trilogy of the same name. Matrix, as Gunkel (2001) points out, is a Latin word that signifies "womb." Consequently, the fictional cyberspace presented in Gibson's Neuromancer is already gendered female. Through this engendering, the novel is presented and functions according to traditional gender stereotypes and biases. Cyberspace, arguably the main female character in the novel, remains for all intents and purposes passive, formless, and receptive, while Case, the cowboy hotshot, is presented as active and is primarily defined by his penetrations into this matrix (pp. 164-165). Second, similar gender constructions are also exposed and examined in many of the initial studies of computer graphics practices and gaming. According to Simon Penny (1995), for example, "computer-graphics production—as seen in commercial cinema, video games, theme park rides, and military simulations—is dominated by a late adolescent Western male psyche and world view" (p. 231). For this reason, the place of female characters within these virtual worlds is often informed by and formed according to gender stereotypes. According to Eugene Provenzo's (1999) analysis of Nintendo, female characters are all too often "cast as individuals who are acted upon rather than as initiators of action" (p. 100). And Shoshana Magnet (2006) traces how these particular gender constructions connect up with the colonial history of the United States, demonstrating the way that players of the video game Tropico are interpellated as heterosexual male colonizers (p. 146). Clearly much more can and should be said about the gendering of game environments, game play, and gamer demographics. We simply want to point out that, insofar as MMORPGs are already wired into the rhetoric and logic of colonial and frontier (mis)adventure, a great deal can be learned from looking at the way gender was constructed and mobilized in the histories and mythologies of the European encounter with the new world of North and South America and the westward expansion of the United States. [4] How and when this took place remains an open question. MMORPGs, for instance, first became popular in south-east Asia, specifically South Korea. Did South Korean game developers, players, and critics conceptualize early MMORPGs, like Lineage I and II and 24 Legend of Mir, as "new worlds" and "frontiers?" Or is the new world metaphor something that comes into play only after MMORPGs become popular in Europe and North America? Although this kind of cross-cultural comparison is beyond the scope of the current essay, such an investigation would not only provide interesting points of comparison but would, insofar as the Korean peninsula has had an entirely different and unfortunate experience with the exercise of colonial power, provide another way to examine the interaction of games and culture. A good place to begin this subsequent investigation would be Dal Yong Jin and Florence Chee's "Age of New Media Empires: A Critical Interpretation of the Korean Online Game Industry" (2008). [5] One interesting and possible exception to this is Frontier 1859. Although still in development, the game's design appears to be sensitive to the complexities of frontier migration: Two worlds collide in the struggle to survive—From the perspective of hope, Emigrants imagined the Frontier as a place to begin a new life. From the perspective of home, Native Americans were here first. Wrong or right, the decisions people made who lived on the Frontier helped them survive the hardships of life. In that process, two lifestyles became extinct, the way of the Native American Indian, and the way of the Wild Frontier. (Frontier 1895, 2007). References Aarseth, E. (July 2001). Computer game studies, year one. Game studies, 1(1), 1-4. Aarseth, E. (2004). Gender trouble: Narrativism and the art of simulation. In N. Wardrip-Fruin and P. Harrigan (Eds.), First person: New media as story, performance, and game (pp. 45- 55). Cambridge, MA: MIT Press. Anderson, K. (1991). 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Hunter (2006). Virtual worlds: A primer. In J. M. Balkin (Ed.), State of play: Law, games, and virtual worlds (pp. 13-28). New York: New York University Press. Leary, T. (1999). The cyberpunk: The individual as reality pilot. In V. Vitanza (Ed.), Cyberreader (pp. 364-372). Boston, MA: Allyn and Bacon. Linden Lab (2008). Secondlife.com. Lopez, B. (1992). The rediscovery of north america. New York: Vintage. Luzzana, C. I. (September 1992). Columbus' otro mundo: The genesis of a geographical concept. Renaissance studies, 6(3-4), 336-351. Magnet, S. (2006). Playing at colonization: Interpreting imaginary landscapes in the video game tropico. Journal of communication inquiry, 30(2), pp. 142-162. Newman, J. (2004). Videogames. New York: Routledge. 28 Ninemoons Family. (15 March 2007). Granado Espada: Dispatches from the New World. Retrieved 4 March 2009 from http://geninemoons.blogspot.com/ Noble, D. W. (Autumn 1964). Cooper, leatherstocking and the death of the american adam. 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Sardar and J. R. Ravetz (Eds.), Cyberfutures: Culture and politics on the information superhighway (pp. 14-41). New York: New York University Press. Schaap, F. (2002). The words that took us there: Ethnography in a virtual reality. Amsterdam: Aksant Academic Publishers. Scott, J. W. (1988). Gender: A useful category of historical analysis. In J. W. Scott (ed.), Gender and the politics of history (pp. 28-50). New York: Columbia University Press. Stenger, N. (1993). Mind is a leaking rainbow. In M. Benedikt (Ed.), Cyberspace: First steps (pp. 49-58). Cambridge, MA: MIT Press. Stephenson, N. (1993). Snow crash. New York: Bantam Spectra. Taylor, T. L. (2006). Play between worlds: Exploring online game culture. Cambridge, MA: MIT Press. Tebbutt, D. (5 March 2007). Is second life a brave new world? IT Week. Retrieved 4 March 2009 from http://www.itweek.co.uk/information-world-review/features/2184795/second-life- brave-worlds Terdiman, D. (8 May 2004). Fun in following the money. Wired. 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First person: New media as story, performance, and game. Cambridge, MA: MIT Press. Woolley, B. (1992). Virtual worlds. New York: Penguin. Zamora, M. (1993). Reading columbus. Berkeley, CA: University of California Press. 30 work_7syilj7unjah5dpq7ojcb4mdlu ---- HOW-SEPTIEMBRE 2010.vp Language Policies in Colombia: The Inherited Disdain for our Native Languages Carmen Helena Guerrero helenaguerreron@gmail.com Universidad Distrital “Francisco José de Caldas” As a contribution to enhance the discussion about the spread of the symbolic power of English in Colombia through a National Bilingual Policy, this paper aims at raising awareness about two main aspects: 1) Colombia has a variety of languages that should be seen as resources and not as problems (Ruíz, 1984) and 2) There is a pattern in our government language policies that tends to favor the elite. The conclusion of this paper is that not much has changed in the linguistic planning in Colombia since the Spanish colonization; privileged groups continue to legislate to favor privileged groups. This approach contributes to enlarge the gap between the haves and the haves not in Colombia. Key words: indigenous, languages, palenquero, creoles, marginalization, language, policy Resumen Como una forma de contribuir a la discusión acerca de la difusión del poder simbólico del inglés en Colombia a través del Plan Nacional de Bilingüismo, este artículo busca despertar la conciencia acerca de dos aspectos fundamentales: 1) Colombia tiene una variedad de idiomas que deberían ser vistos como recursos y no como problemas (Ruiz, 1984) y 2) existe un patrón en relación con las políticas lingüísticas en nuestro gobierno que tienden a favorecer las élites. La gran conclusión es que no ha cambiado mucho en la planeación lingüística en Colombia desde la colonización española donde los grupos privilegiados legislaban para favorecerse a ellos mismos. Este tipo de actitudes contribuye a agrandar la brecha entre quienes lo tienen todo y quienes no tienen nada. Palabras clave: Lenguas, indígenas, Palenquero, Creole, políticas, lingüísticas Introduction The Ministry of Education of Colombia has produced a series of guidelines to establish the national standards for the core areas of the Colombian curriculum which are Spanish, mathematics, social and natural sciences, and citizenship competences. To these series the MEN added the “Estándares básicos de HOW 16, December 2009, ISSN 0120-5927. Bogotá, Colombia. Pages 11-24 11 SEPT 30-HOW-SEPTIEMBRE 2010.prn competencias en lenguas extranjeras: Inglés. Formar en lenguas extranjeras: ¡el reto!” as part of its “Programa Nacional de Bilingüismo (PNB)” (National Bilingualism Program). The production of these standards is inscribed within the government proposal of the current President of Colombia, Álvaro Uribe Vélez, called “La revolución educativa” (Educational revolution). The goal of the educational revolution is to improve the quality of education and extend access to education in order to promote the social and economic development of the country and better the living conditions of Colombians. To reach this objective, the national government set three basic policies: 1) Extend education coverage, 2) Improve the quality of education, and 3) Improve the efficiency of education (Ministerio de Educación Nacional, n/d, p. 8). Despite the fact that, initially, favoring the teaching of English was neither included in any of these policies nor in the “Plan decenal de educación 1996-2005”, a document that established the direction of education for ten years, it was added later as a national policy in the “Plan sectorial 2006-2010”. All of these documents state a deep interest in the improvement of the quality of education in Colombia, and the need to favor less privileged groups; nevertheless, there is a lack of coherence between the sociolinguistic reality in Colombia and the projects undertaken by the Ministry of Education. In the National Constitution of 1991 Colombia is acknowledged as a multicultural and multilingual nation where there is a convergence of indigenous languages, creoles, several foreign languages, and Spanish. In this paper, I would like to bring to the surface the existence of multilinguism in Colombia and relate it to language policies. My main objective here is to raise awareness of the fact that these languages are real, have real speakers and are alive today. It is not new that multilingualism (especially the type that is related to indigenous languages and creoles) has been permanently overshadowed by monolingual ideologies and poor language polices, but the launch of the PNB has affected (and will continue to affect) negatively the value, recognition, use, study, teaching and learning of these and all the other languages different from English that share the Colombian territory. Indigenous Languages According to the National Planning Department (DNP), the official organism in charge of tracing the directions of all national polices, the indigenous population in 12 HOW, A Colombian Journal for Teachers of English Carmen Helena Guerrero SEPT 30-HOW-SEPTIEMBRE 2010.prn Colombia is 1,378,884, which represents 3.3% of the national populace, and these citizens live in the 33 departments of Colombia. Although a small percentage of this population is monolingual in Spanish, the majority of them speak any of the sixty-six languages that are alive today (Landaburu, 2005; Pineda Camacho, 1997). This is a small number of indigenous languages compared to the large number of languages found by the Spaniards when they first arrived in America. The multilinguism found by the Spanish conquistadors provoked a negative impression, so that they referred to the large number of languages spoken by the indigenous peoples as an “illness” that was spread along all the different groups found in the new world. There was such disregard (or ignorance) for our indigenous languages that Christopher Columbus re-named as many things as he could (he re-named the island of Guanahani, the name given it by the Indians, as San Salvador; he re-baptized two Indians he took back to Spain with the names of Don Juan de Castilla and Don Fernando de Aragón) (Patiño Rosselli, 2000; Todorov, 1984). This account of the first encounters of the colonizers with the natives gives evidence that the prevalent ideology of devaluing our indigenous peoples and everything related to them has deep roots in our historic past. The linguistic diversity was a problem for evangelization purposes and for business; the Spaniards’ interest was not in learning indigenous languages but in subjugating the indigenous peoples. To achieve their goal, their policy was to teach Castilian to the children of the indigenous chiefs, as well as Catholicism and government skills (Pineda Camacho, 2000). Soon the Church realized that aborigines were reciting prayers but did not understand their meaning and started to promote the learning of indigenous languages among its missionaries so they could evangelize indigenous peoples in their native languages. The Spanish Crown, headed by Philip II, supported this initiative but only for evangelization purposes while at the same time encouraging the spread of Castilian, which was clearly a policy of transitional bilingualism (De Mejía, 2005; Patiño Rosselli, 2000; Pineda Camacho, 2000). All of this period was characterized by a struggle within the Church; some missionaries, especially “mestizos” (children of Spaniards and Indigenous peoples), wanted to keep the indigenous languages (which they spoke) but the Spanish missionaries wanted to conduct evangelization only in Spanish. The discrepancy in the application of linguistic policies resulted in some aborigines learning Spanish and HOW 16, December 2009, ISSN 0120-5927. Bogotá, Colombia. Pages 11-24 13 Language Policies in Colombia: The Inherited Disdain for our Native Languages SEPT 30-HOW-SEPTIEMBRE 2010.prn some not, a situation which was used by the “Ordenanzas” (people in power in the new Colony) as a means for segregation (Pineda Camacho, 2000) Years later, during the government of Charles III, this policy changed drastically; indigenous languages were prohibited, and Castilian was declared the only acceptable language (Landaburu, 2005; Mar-Molinero, 2000; Patiño Rosselli, 2000). The development of maritime commerce conducted in Spanish, and the insurgency of Tupac Amaru in 1780-1781, triggered the interest of Charles III to forbid the indigenous languages. This policy continued during the rest of the colonization period, and speaking Spanish (Castilian) was required in order to obtain citizenship in the new colonies. The marginalization towards indigenous peoples continued during the era of the republic, when a great number of the population was “Criolla” (Creole, the name given to children of Spaniards born in America) and spoke Spanish. The “Criollos” did not want the indigenous to speak Spanish; they wanted to keep the aborigines marginalized linguistically and culturally due to three main reasons: 1) as a control mechanism; 2) the “Criollos” thought that if the indigenous peoples learned Spanish they would become lazy and corrupted; and 3) the “Criollos” wanted the linguistic difference as a way of discrimination (Pineda Camacho, 2000). Feeling left out from society, the aborigines did not see any purpose for speaking Spanish. Some years after the independence from Spain, in 1886, the new republic, then called “La Gran Colombia”, wrote its first Constitution. In it, Spanish was designated as the official and only language. This Constitution was characterized by a strong sense of cohesion and homogeneity, evidenced by the fact that it did not acknowledge the multiculturalism or multilingualism of the country (Pineda Camacho, 2000); the natural implication for indigenous populations (and Afro-Colombians) was that they should drop their languages (that at the time, and until recently, were not recognized as languages but as “dialects”) and speak Spanish instead. This policy succeeded for more than one hundred years and was strengthened by the fact that the education of indigenous groups was in the hands of Catholic missionaries who conducted it in Spanish (De Mejía, 2005). It has been until very recently (1962) that indigenous peoples have started to claim their linguistic rights which were taken away, first by Spanish conquistadors and later on by their own flesh: the “Criollos”. The early 70s witnessed the emergence of indigenous group organizations whose purpose of reclaiming their lands was 14 HOW, A Colombian Journal for Teachers of English Carmen Helena Guerrero SEPT 30-HOW-SEPTIEMBRE 2010.prn accompanied later by a demand for the acknowledgment of their culture and languages. In 1978, for the first time, the Ministry of Education with the issue of Decree 1142 recognized that indigenous populations had the right to be educated in their own languages and design a curriculum that addressed their contexts and needs (De Mejía, 2005; Jiménez, 1998; Landaburu, 2005). In 1991 with the issue of the new National Constitution, Colombia was acknowledged as a multicultural and multilingual nation with the recognition of indigenous communities and minority groups as legitimate Colombian citizens. Spanish was still designated as the official language of the country, but the indigenous languages were included as official in the indigenous territories, which implied that the state would guarantee bilingual education and respect for their cultural identity (Constitución Política de Colombia, 1991). With the issuance of Law 115 in 1994, the National Government ratified the rights of indigenous groups and recognized the need for ethno-education. Ethno-education in this context means the right to foster the culture and language of the indigenous peoples. To ensure this, their education will be conducted in their mother tongue and in Spanish and teachers should be bilingual and, preferably, members of the same indigenous community. Indigenous languages have gained recognition little by little now 500 years after the discovery of America, but still there is a long way towards the concretization of some of the objectives registered in the Constitution and Law 115. It is still uncertain what will happen with the indigenous languages in the years to come, considering that in the past the competition for prestige and resources was only against Spanish, but now, with the launching of the PNB, English enters as a new and powerful player. What is clear is that more decisive governmental efforts and investment are necessary in order to preserve the language and culture of our indigenous groups in Colombia. Unfortunately, as Omoniyi (2003) states: “Language policies sometimes never rise beyond the page of the document on which they are printed” (p. 16). Afro-Caribbean Languages Besides the more than sixty-six indigenous languages that exist today in Colombia, there are two Afro-Caribbean languages that have developed since the colonial times: “Palenquero”, a Spanish-based creole spoken in San Basilio de Palenque, and an English-based creole spoken on San Andrés Island. It seems that HOW 16, December 2009, ISSN 0120-5927. Bogotá, Colombia. Pages 11-24 15 Language Policies in Colombia: The Inherited Disdain for our Native Languages SEPT 30-HOW-SEPTIEMBRE 2010.prn these creoles developed due to two main reasons: 1) The practice of slavery: Spaniards brought a large number of Africans to work in agriculture, mines, and sugar cane plantations (Holm, 1984; Patiño Rosselli, 1992) and 2) “Cimarronismo” (maroons) (Patiño Rosselli, 1998). Until very recently, these two languages were invisible in Colombia, and very little was known about them. The Ministry of Culture has started a project led by Jon Landaburu to revive and maintain these and the indigenous languages spoken in Colombia. Palenquero During the colonial period, Spain brought over a huge number of Africans to enslave them and send them to work in agriculture and mines, particularly in the Caribbean region. Africans never accepted their condition as slaves and always sought ways to recover their freedom, which motivated them to escape and settle in isolated areas. San Basilio de Palenque is one of more than forty settlements and where “Palenquero” originated. This small village is located about 60 km from Cartagena and 200 km from Barranquilla, on the north coast of the country. It is not clear when exactly San Basilio de Palenque was founded; Morton (2005) and Schwegler and Morton (2003) state that it must have been between 1650 and 1700, but Lipski (1987) places it around 1599 and Megenney (1986) in 1608. Despite the discrepancies in dates, they all agree that it was Domingo Bioho, an African slave who claimed to be King Benkos from an African royal family, who led a rebellion and was followed by thirty other slaves who escaped from Cartagena; together they built a fortified site and founded a community of maroons (cimarrones). They built these fortified settlements with sticks (“palos”), hence the name “Palenqueros”, to resist the attempts of the Spaniards to recapture them and also to keep whatever they had built in their short period of freedom (Morton, 2005; Colombia Aprende, 2008; De Mejía, 2005; Patiño Rosselli, 1992; Pineda Camacho, 2000). By 1603, the official reports warned about the increasing number of “Palenques” near Cartagena (capital city of Bolivar), and this motivated the Governor of Bolivar to sign an agreement with the inhabitants of Palenque de San Basilio in which the former acknowledged the independence of the “Palenqueros” as long as the latter did not encourage “cimarronaje” (marronage) and did not take in more escapees. Despite this agreement, for almost a century the “Palenqueros” had to fight the colonizers to 16 HOW, A Colombian Journal for Teachers of English Carmen Helena Guerrero SEPT 30-HOW-SEPTIEMBRE 2010.prn keep their freedom and their lands until 1691, when the King of Spain agreed to confer on them the lands they had cultivated and where they had built their towns (Patiño Rosselli, 1998; Pineda Camacho, 2000). According to Morton (2005), this type of agreement took place only with Palenque de San Basilio, which in a way determined the unique “linguistic and cultural evolution of this village” (p. 34). These communities of “Palenqueros” communicated in Spanish and their native languages or in a pidgin used on the African coast which spawned the “Palenquero” (Patiño Rosselli, 1991; 1998; Pineda Camacho, 2000; Oceanic linguistics special publication, 1975, p. 125-127), and it has been reported as the only Spanish-based Creole that has survived in the Caribbean (Dieck, 1998; McWhorter, 1995; Patiño Rosselli, 1991, 1992; Pineda Camacho, 2000). Different from indigenous peoples, African slaves were kept marginalized from formal education; their only instruction was aimed towards their conversion to Catholicism. This isolation propitiated their frequent use of their own Creole and of a variety of Spanish that was very different from the norm (Pineda Camacho, 2000). The marginalizing attitude has continued until today in such a way that having black color of skin has been related to poverty, backwardness, and underdevelopment; being perceived in this negative way has granted “Palenqueros” a stigmatization that has affected the interest of new generations to speak their language (Schwegler, 1998; Schwegler & Morton, 2003). During the Republic years, the spread of Castilian (or Spanish) became stronger, and it forced “Palenquero” to be restricted to the area of San Basilio. Since then, the inhabitants of San Basilio de Palenque have been bilingual in “Palenquero” and Spanish, using the former as their first and home language (De Mejía, 2005; Pineda Camacho, 2000), but this is an asymmetrical bilingualism because while everybody understands and speaks Spanish, young people and children understand “Palenquero” but do not speak it fluently or do not speak it at all (Lipski, 1987; Patiño Rosselli, 1992). “Palenquero” was documented for the first time by Ochoa Franco in 1945 and recognized as Creole by Bickerton and Escalante in 1970. (De Mejía, 2005; Oceanic Linguistics Special Publications, 1975, p. 132-133; Schwegler, 1998). Due to its unique characteristics, it has been regarded as a linguistic relic, but it was only until the mid 1980s when the government started to take action to give “Palenquero” official status through the program ‘Education for identity’. Thanks to this initiative, HOW 16, December 2009, ISSN 0120-5927. Bogotá, Colombia. Pages 11-24 17 Language Policies in Colombia: The Inherited Disdain for our Native Languages SEPT 30-HOW-SEPTIEMBRE 2010.prn the language is being used at school, and there are projects running to produce a Palenquero-Spanish bilingual dictionary as well as other printed materials (De Mejía, 2005; Patiño Rosselli, 1992; Pineda Camacho, 2000). In 2005, San Basilio de Palenque was declared a “Masterpiece of the oral and intangible heritage of humanity” by UNESCO, which has triggered more interest from the Colombian national government towards the preservation of the language. San Andrés and Providence Creole English San Andrés and Providence make up the Caribbean archipelago which is the smallest Colombian “departamento”. Its population is approximately 62,000 and about half is of African descent (Decker & Keener, 2001; Morren, 2001). The situation of San Andrés and Providence is the result of the negligence of the State and the role of Church in education. Spain took possession of the islands of San Andrés and Providence in 1641, but by then, a large number of Puritan colonists had arrived in the island (Morren, 2001); in addition, during the early 18th century, immigrants from Jamaica and other English speaking countries settled there and Spain lost control of the island (Decker & Keener, 2001; Forbes, 2005; Holm, 1984; Patiño Rosselli, 1992; Pineda Camacho, 2000). In 1786, a treaty ceded the islands back to Spain, but English inhabitants were allowed to stay as long as they swore allegiance to the Spanish Crown, converted to Catholicism and spoke Spanish (De Mejía, 2005). Despite these requests and due to the presence of a large population of English speaking settlers, most people on the island spoke only English, which led the governor in 1803 to ask the central government to send Irish missioners to evangelize the inhabitants in that language, but it was never granted. After the independence of New Granada from Spain in 1822, the inhabitants of the island adhered to the Colombian republic (Morren, 2001; Pineda Camacho, 2000). In 1845, Philip Beekman Livingston Jr., a Baptist pastor, arrived in the island and started to teach slaves reading and writing in English (this activity was rejected by the white people of the island). Two years later, he founded the Baptist church and established a school. Both the Church and the school used English as the language of instruction, which helped in the spread of both this religious group and English. By 1850, most islanders had converted to the Baptist religion and a significant number of 18 HOW, A Colombian Journal for Teachers of English Carmen Helena Guerrero SEPT 30-HOW-SEPTIEMBRE 2010.prn them could read and write in English in addition to speaking their own languages (Morren, 2001; Patiño Rosselli, 1992; Pineda Camacho, 2000). In 1869 the President of Colombia, Santos Acosta, signed a decree in which San Andrés and Providence’s English was acknowledged as a language. This decree ordered the translation of the National Constitution in effect at that time, “Constitución de Río Negro”, and the appointment of translators for official events. This situation did not last because with the writing of the National Constitution of 1886, which aimed at creating a sense of national identity by homogenizing as much as possible the cultural practices of Colombians, it was declared that Catholicism was the official religion of the country and that education should follow the principles of Catholic dogma. Although Spanish was not explicitly designated as the official language, it was actualized as such in the whole Colombian territory. This Constitution was harmful to San Andrés and Providence’s inhabitants because they were forced to adopt a new religion and a new language. By 1926, due to the pressure of the Catholic Church, many islanders converted to Catholicism; one year later, Law 17 of 1927 prohibited the use of English to designate public places, and some years after, in 1943, the use of the vernacular language was prohibited to designate public places, to be used in schools, or to be used in the official documents of the island (Pineda Camacho, 2000). Nevertheless, islanders continued using Standard English for school and Church and Caribbean Creole English for oral communication (Grimes, 2000). Despite the requests made to the national government in several reports by educational inspectors (from 1912 to 1937) to implement a bilingual program in the island that responded to the sociolinguistic characteristics of the population, the response of the government was to eliminate English from schools and place it as a second language subject in high school, as in the rest of the country. The consequences of this policy were very negative because students did not master Standard English, and this put them in a disadvantageous academic situation (Dittmann, 1992). The Colombian government, led by General Rojas Pinilla, then President, in 1953 declared San Andrés and Providence a free port and promised the construction of an airport, roads, and the arrival of progress. This caused a tremendous change in the economy and demographics of the islands because it attracted the interest of a lot of mainland Colombians. Due to their superior knowledge of Spanish, Colombian laws, and business expertise, they soon owned most businesses on the island. Their HOW 16, December 2009, ISSN 0120-5927. Bogotá, Colombia. Pages 11-24 19 Language Policies in Colombia: The Inherited Disdain for our Native Languages SEPT 30-HOW-SEPTIEMBRE 2010.prn presence also produced a change in language use, and Spanish replaced English and Creole in official events, mass media, business transactions and, of course, Church and education. Since 1954, as part of the national program to “Colombianize” the islanders, Spanish became the official language. However, Baptist churches still prefer English for their services and schools and use both English and Spanish as the medium of instruction (MOI); at home most native islanders use Creole English as well for interaction with friends (Dittman, 1992; Forbes, 2005; Morren, 2001; Patiño Rosselli, 1992). Today in San Andrés and Providence three languages converge: Creole, English and Spanish. At the same time, conflict emerges as each of these languages is perceived and valued differently by various groups. Most religious leaders (who have a strong influence in the island due to their historical presence there) think that Islander English (or Creole) is a legitimate language while Spanish is an imposition that threatens islanders’ native language, culture, and identity. Political leaders have a different opinion and consider that Islander English is broken English or inferior English and should be eradicated (Morren, 2001; Pineda Camacho, 2000). And in a different group, some teachers think that there is a lack of articulation between school and the community and demand the inclusion of English as a MOI probably based on the continuum that exists between Creole English and English (Dittman, 1992; Morren, 2001; Holm, 1984; Patiño Rosselli, 1992). In 1980, the national government issued Decree 2347 whose purpose was to mandate the professionalization of high school bilingual graduates of the island to incorporate them as teachers in an experimental bilingual program that was running in some elementary schools in the archipelago. The project was coordinated by the “Centro Experimental Piloto de las Islas” with the advice of the “Centro Electrónico de Idiomas”, an annex of the Ministry of Education in charge of English teaching in the country at the time, and the British Council (Dittmann, 1992). The project was adopted officially by the Secretary of Education in 1988; seven primary and three secondary schools have been recognized as bilingual schools where Standard Caribbean English and Spanish are used as the MOI; Creole English is, however, marginalized from school and used only for informal interaction (De Mejía, 2005). Although the National Constitution of 1991 acknowledges the right of ethnic groups to conduct education in their own languages, it refers more to indigenous peoples; Afro-Colombians are mentioned only in Article 55 which states that in two 20 HOW, A Colombian Journal for Teachers of English Carmen Helena Guerrero SEPT 30-HOW-SEPTIEMBRE 2010.prn years from 1991, the government will create a special commission to study the situation of black communities who have lived on the Pacific coast and in other areas of the national territory in order to grant them the rights to land, protection of their cultural identity, and support for their economic and social development. In 1993, the national government issued Law 70 to officially acknowledge black communities of the country and establish measures to grant them the rights to land, identity, culture, and social development. Specifically, Chapter VI of this law refers to protection of cultural identity and sets the bases of the autonomy of Afro-Colombian communities to design a curriculum that responds to their particular needs. Despite this, there is no explicit mention of San Andrés Creole English, and Standard Caribbean English. As a consequence of the convergence of different historical events and national policies, today bilingual education is permitted on the island but is not observed completely due to several factors such as lack of instructional materials, lack of teachers’ training in bilingual education, the large number of Spanish monolingual teachers, and the importance of Spanish for the economy of the island (Decker & Keener, 2001). With the National Bilingualism Project, there has been a renewed interest in San Andrés as a potential site for immersion courses (Grimaldo, 2007); the results are still to be seen because the language attitudes of mainland Spanish speakers in Colombia still think of San Andres’ English as broken English, hence a variety of very low prestige. Conclusion Since the Spanish colonization, language policies in Colombia have been marked by a constant asymmetry that values the language of the powerful and disregards the languages of the powerless. More than 500 years after the so-called discovery of America by Christopher Columbus, the situation is not very different. While during the colonial years Spanish was favored and perceived as the language of modernization and progress, English is the language associated with those characteristics today. And yesterday, as today, indigenous languages and creoles are treated as second class languages. Also relevant is the way in which the official discourse, no matter the epoch, has constructed attitudes towards minority languages to the point that mainstream HOW 16, December 2009, ISSN 0120-5927. Bogotá, Colombia. Pages 11-24 21 Language Policies in Colombia: The Inherited Disdain for our Native Languages SEPT 30-HOW-SEPTIEMBRE 2010.prn Colombians do not consider learning one of our languages as a second language. The State has a crucial responsibility in this lack of interest because not only does it not promote the study of our languages but discourages people who speak them from converting them into cultural or linguistic capital. Anecdotal evidence shows that in graduate programs where people need to demonstrate proficiency in a second language, people who speak an indigenous language have had to struggle to get their languages accepted to fulfill that requirement. It is too early to predict the outcomes of the national bilingualism program set by the MEN, but it is worrisome to see how this project is repeating the same patterns of inequality, discrimination, marginalization, and segregation that were used to impose Spanish more than five hundred years ago. It is easy today to associate indigenous peoples and most Afro-Colombians with poverty and backwardness and to blame them for that, but if we look closer and carefully, we can see that the causes of their disadvantaged situation have profound roots embedded in our history and in an ideology of superiority vs. inferiority. References Colombia Aprende (2008) Cimarrones y cimarronajes. Retrieved from: http:// www.colombiaaprende.edu.co/html/etnias/1604/article-82836.html Constitución Política de Colombia (2000) Retrieved from: http://www.banrep.gov.co/ regimen/resoluciones/cp91.pdf De Mejía, A.M. (2005). Bilingual education in Colombia: Towards an integrated perspective. In De Mejia, A.M. (Ed.), Bilingual education in South America (pp. 48-64). Clevedon: Multilingual Matters Ltd. Decker, K. & Keener, A. (2001). A report on the English-based Creole of San Andres and Providence Islands, Colombia. SIL International. Dieck, M. (1998). Criollística Afrocolombiana. In Maya, L.A. (Ed.) Geografía humana de Colombia: Los Afrocolombianos. Tomo VI (pp. 303-338). Bogotá: Instituto Colombiano de Cultura Hispánica. Dittmann, M. (1992). El criollo sanandresano: Lengua y cultura. Cali: Universidad del Valle. Forbes, O. (2005). Creole culture and language in the Colombian Caribbean. Centro de Medios independientes de Colombia. Retrieved from: http://colombia.indymedia.org/news/2005/ 05/25461.php Grimaldo, J.C. (2007). Programa Nacional de Bilingüismo. Colombia 2004-2019. Talk presented in Bogotá during the “Talleres de apropiación de los Estándares”. Grimes, B.F. (2000). Ethnologue: Languages of the world. 14th edition. Dallas: SIL International. Holm, J. (1984). Central American English: Our hemisphere’s best-kept secret. Geolinguistics, 10, 57- 73. 22 HOW, A Colombian Journal for Teachers of English Carmen Helena Guerrero SEPT 30-HOW-SEPTIEMBRE 2010.prn Jiménez, N. (1998). Etnoeducación: Política oficial para la educación en comunidades indígenas. In Trillos, M. (Ed.), Educación endógena frente a educación formal (pp. 59-79). Bogotá, Universidad de los Andes: Centro Colombiano de Estudios de Lenguas Aborígenes. Landaburu, J. (2005). La situación de las lenguas indígenas de Colombia: prolegómenos para una política lingüística viable. En Amérique Latine Histoire et Mémoire, No. 10-2004 - Identités: positionnements des groupes indiens en Amérique latine, Retrieved from: http:// alhim.revues.org/document125.html. Retrieved April 13th 2007. Lipski, J. (1987). On the construction ta + infinitive in Caribbean “Bozal” Spanish. Romance Philology, 40 (4), 431-450. Mar-Molinero, C. (2000). The politics of language in the Spanish-speaking world. London and New York: Routledge. Megenney, W. (1986). El Palenquero. Un lenguaje post-criollo de Colombia. Bogota: Instituto Caro y Cuervo. LXXIV. McWhorter, J. (1995). The scarcity of Spanish-based creoles explained. Language in Society, 24 (2), 213-244. Ministerio de Educación Nacional (n/d) La revolucion educativa. Retrieved from: http://www.mineducacion.gov.co/1621/article-85576.html Morren, R. (2001). Creole-based trilingual education in the Caribbean archipelago of San Andres, Providence and Santa Catalina. Journal of multilingual and multicultural development, 22 (3), 227-241. Morton, T. (2005). Sociolinguistic variation and language change in el Palenque de San Basilio (Colombia). Doctoral Dissertation. Philadelphia, Pennsylvania: University of Pennsylvania. Oceanic Linguistics Special Publications, 14 (1975). A Bibliography of Pidgin and Creole Languages. 132-133. Omoniyi, T. (2003). Language ideology and politics. A critical appraisal of French as a second official language in Nigeria. AILA Review, 16, 13-25. Patiño Rosselli, C. (1991). Español, lenguas indígenas y lenguas criollas en Colombia. Bogotá: Instituto Caro y Cuervo. Patiño Rosselli, C. (1992). La criollistica y las lenguas criollas de Colombia. Thesavrvs. Boletin del Instituto Caro y Cuervo. Tomo XLVII (2) 233-264. Patiño Rosselli, C. (1998). Relaciones de contacto del Criollo palenquero de Colombia. Forma y Función, 11, 77-101. Patiño Rosselli, C. (2000). Apuntes de lingüística colombiana. Forma y Función, 13, 67-84. Pineda Camacho, R. (1997). La Constitución de 1991 y la perspectiva del multiculturalismo en Colombia. Alteridades, 7 (14), 107-129. Pineda Camacho, R. (2000). El derecho a la lengua. Historia de la politica linguistica en Colombia. Estudios Antropologicos No. 4. Bogota: Universidad de los Andes. Ruiz, R. (1984). Orientations in language planning. The Journal for the National Association for Bilingual Education, 8(2) 15-34 Schwegler, A. (1998). El Palenquero. In: M. Perl and A. Schwegler (Eds.), America negra. Panoramica actual de los estudios linguisticos sobre variedades hispanas, portuguesas y criollas, (pp. 220-291). Vervuert: Iboeroamericana. HOW 16, December 2009, ISSN 0120-5927. Bogotá, Colombia. Pages 11-24 23 Language Policies in Colombia: The Inherited Disdain for our Native Languages SEPT 30-HOW-SEPTIEMBRE 2010.prn Schwegler, A. & Morton, T. (2003). Vernacular Spanish in a microcosm: Kayetano in El Palenque de San Basilio (Colombia). Revista internacional de linguistica iberoamericana, 1 (1), 97-159. Todorov, T. (1984). The conquest of America. The question of the other. (Richard Howard [Trans.]) New York: Harper & Row, Publishers. The Author Carmen Helena Guerrero holds a Ph. D. in Second Language Acquisition and Teaching. She also holds an MA in Second Language Acquisition and Teaching and an MA in Applied Linguistics to the teaching of English. Her research interests include Critical Discourse Analysis, Critical Pedagogy, and Educational Policies. She is a faculty member of the Maestria en Comunicacion Educación at Universidad Distrital. SEPT 30-HOW-SEPTIEMBRE 2010.prn work_7vcqd2sywfdvlpfcw7ckv3xgyy ---- wp-p1m-38.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-38.ebi.ac.uk no 218197407 Params is empty 218197407 exception Params is empty 2021/04/06-02:09:22 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. Message ID: 218197407 (wp-p1m-38.ebi.ac.uk) Time: 2021/04/06 02:09:22 If you need further help, please send an email to PMC. Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_7yct5pm5erek7mzoewbsqid3ri ---- Globalization and Religion: The Case of Malacca and the Work of Robert Morrison Religions 2012, 3, 1075–1084; doi:10.3390/rel3041075 religions ISSN 2077-1444 www.mdpi.com/journal/religions Article Globalization and Religion: The Case of Malacca and the Work of Robert Morrison Peter Tze Ming Ng SKH Minghua Theological College, Glenealy, Central, Hong Kong; E-Mail: peterng.cuhk@gmail.com Received: 2 October 2012; in revised form: 6 November 2012 / Accepted: 7 November 2012 / Published: 7 November 2012 Abstract: Religion has long been a significant factor in the process of globalization. In this article, the author attempts to explore and review religious factors involved in the history of Malacca (Melaka) and in the missionary work of Robert Morrison in the early 19 th century. Malacca has long been a meeting place for various religions in their respective processes of globalization. Robert Morrison was the first Protestant Missionary to come to the Chinese Mainland. He arrived in 1807. However, after 10 years of working in Canton and Macau, he made a proposal for setting up a mission school in Malacca, hence the Anglo-Chinese College of 1818. It was found that, indeed, Morrison had learned much from his experiences in China and in Malacca, especially in paying due respect to Chinese culture. Keywords: globalization; religion; Robert Morrison; Anglo-Chinese College; Malacca (Melaka) Introduction Though the term ‗globalization‘ is often thought of as a modern concept, the process of globalization is an old one, especially in regard to the cultural transmission beyond national borders, and can be traced back centuries. Religion has been a vital factor in this process. In his exploration of the relationship between ‗globalization‘ and ‗religion‘, Peter Beyer affirmed that religion as culture had played a significant role in the development, elaboration and problematization of global society ([1], Introduction). Indeed, there has been a growing awareness that ‗globalization‘ and ‗religion‘ are not quite separate entities. Nor should ‗religion‘ be seen as an ‗outside‘ respondent or ‗victim‘ in the process of globalization. Modern scholars began to see religion as an integral part of globalization and OPEN ACCESS Religions 2012, 3 1076 reckon that it is one that was a proactive rather than a regressive force in the development of globalization, being intertwined in a way that influences most of the worldwide political, economic and cultural processes ([2], Introduction). It should also be noted that contemporary globalization is the outcome of a long historical process that includes the historical development of religious movements around the globe, hence the religious factor in the context of globalization ([2], pp. 145–165). The spread of religion should be understood, not simply as a result of migration of religious believers because of political or economic reasons, but that ‗religion‘ in itself is an important moving force in the process of globalization, such as in the Christian movement of ‗the evangelization of the whole world‘. In this paper, I shall use the history of Malacca and the work of Robert Morrison as a case to review the relevant connections between religion and globalization. There are indeed some significant findings we could extract from this lively case of Robert Morrison and Malacca. History of Malacca The history of Malacca revealed the fact that religion has indeed been a significant factor in the development of globalization in the region. As we study Malacca closely, we find that the city has a unique history of its own that could provide some good insight not only in the study of Protestant missionaries, such as Robert Morrison in setting up schools for inter-cultural dialogues, but also in the study of the impact of other religious traditions in the area, such as Hinduism, Buddhism, Confucianism and Islam. Malacca is a typical example of how the great religions have imprinted their many influences on a place. The city has been a busy trading centre in Southeast Asia for centuries, lying on the southern part of the Malay Peninsula and providing a comfortable port of call for all trading vessels in their passage between the Indian Ocean and the South China Sea. It has also been overtaken as a colony by various peoples from East Asia and Europe. Indian traders first came to the peninsula in the first century A.D. The Indian Emperor, Harsha (606–647 A.D.) was a patron of Shaivism and Buddhism. He sent missionaries to the South during his reign, hence starting the spread of Indian cultures and religions, including Hinduism and Buddhism, throughout Southeast Asia. Hinduism became the state religion of many Southeast Asian states, including Malaysia, until the 13 th century. Indian (Hindu) beliefs and culture were regarded as a higher culture of the time and, hence, it was natural that the Malay people had adopted Indian cultures into their own culture. That was why Malay culture used to be foundationally close to Indian and Hindu cultures in many aspects [3]. Then came the Muslims in the 13 th centuries A.D. The movements of the Muslims could be seen in a global context, as it was partly because of their defeats by the Christian Crusaders in Europe in the eleventh and twelve centuries that the Muslims were held back from Europe and began to move from the ‗Near East‘ to the ‗Far East‘, as well as to Southeast Asia. There was a wide spread of Islamic religion especially under the Ottoman Empire in 1300 A.D., which spanned from Asia Minor to India and to Southeast Asia. As a result, there was not only a huge expansion of trade and commerce, but also the spread of Islamic civilization, including all the cultural and social aspects of the Islamic religion ([3], pp. 7–13). When the Muslims came to Malaysia, there was already the existence of Indian cultures, with Hindu and Buddhist temples, beliefs and rituals in the area. The intrusion of Islamic religion furthered another hybrid culture and a syncretised mix of religious traditions ([4], Religions 2012, 3 1077 pp. 69–90). Since 1414, the ruler (sultanate) of Malacca had become a Muslim. Islam then became the state religion of Malacca until the arrival of the Portuguese from Europe in 1511. Since the beginning of the 15 th century, the Chinese came to establish relationships with the Malacca Sultanate. The Chinese Emperor Yongle sent huge naval expeditions under the leadership of Admiral Zheng He (1371–1433) and visited Malacca six times for trade and commerce. As a result, the Sultanate sent tributes to China, and in return, China sent her princess to be married to the Sultan. China also sent out 500 Chinese men to accompany the princess and they had brought with them Chinese beliefs and culture, which were later transformed to become ‗Baba Nyonya Culture‘, another syncretised mixture of Chinese and Malay cultures in Malacca [4,5]. Chinese people settled in Malacca and married Malay ladies down through the centuries. The Baba Nyonya Culture had helped in many ways to preserve the Chinese culture for the younger generations and held them together within the Chinese community in Malacca. Protestant missionaries, like Robert Morrison, found themselves interested in staying in Malacca simply because of this Chinese community. Though they had already been living in Malacca for a few centuries, they had kept the Chinese language and culture in many ways. While the Qing government was enforcing a ―closed-door policy‖ at the beginning of the 19 th century, the Protestant missionaries could still work with this Chinese community in Malacca, as a step towards preparing themselves for the opening of China in later years. That was why Morrison launched his plan for setting up the Anglo-Chinese College at Malacca in 1818, so as to have closer contact with the Chinese community there. Christianity came to Malacca in 1511. This was another wave of cultural globalization. It was the Portuguese who captured Malacca in 1511, in order to seize the control of all trade and commerce through the Straits of Malacca. They ruled over the land for 130 years, till 1641. The coming of the Portuguese at this time signified also the religious situation in Europe. It was the decline of power of Roman Catholicism in Europe that had pushed the kings in Spain and Portugal to extend their support to the explorers of the ‗New World‘, so as to help also for the expansion of both their kingdoms and the Roman Catholic Church by military forces. Hence, both the army and the missionaries were sent out together with the explorers and colonizers such as Christopher Columbus (1451–1506) and Vasco da Gama (1460–1524). It was Alfonso de Albuquerque (1453–1515) who had the support from the king of Portugal and captured Malacca for the king in return. This Portuguese colonization of Malacca opened the door for the spread of Christianity in the Far East and the evangelization work of the Roman Catholics for over a century. The most famous Catholic missionary was St. Francis Xavier (1506–1552) who came to Malacca on 8 th May 1545. St. Francis Xavier, who was well-known as ‗the Apostle of the Indies‘, had been dreaming of setting up a mission station at Malacca and expanded his missionary work to Japan, China and India. Unfortunately, he died on 3 rd February 1552. The St. Francis Xavier Church was built in memory of his work in Malacca ([3], pp. 14–21). Then, in the year 1641, came the Dutch explorers and colonizers. The Dutch Reformed missionaries followed the examples of the Roman Catholics and started their evangelization work in Southeast Asia and the Far East, using Malacca as a missionary base. It is also interesting to note that the Dutch missionaries were more interested in the Chinese community than the Malay people in Malacca, as they were looking beyond the state to the reach of China in the Far East. The missionaries started translating the Bible into Chinese and attempted reaching out to the Chinese community in Malacca. Their work, especially their activities in education and publication, had inspired the two missionaries Religions 2012, 3 1078 from the London Missionary Society, William Milne and Robert Morrison, who came in the early 19 th century. With the rise of her military forces and dynamic sea power, Great Britain took over Malacca during the Napoleonic wars of 1795, and officially signed the Treaty of London with the Dutch colonies in 1824. The capture of Malacca opened the door to Protestant missionaries from the United Kingdom. That was why William Milne and Robert Morrison were sent to the Far East by the London Missionary Society and they arrived in Malacca in the early 1810s. They learned from previous missionaries and especially the Dutch Reformed missionaries‘ approach to the Chinese community in Malacca. That was also why Robert Morrison had made a proposal in his ―Ultra-Ganges Mission Plan‖ to set up a mission school for the Chinese in Malacca. The Anglo-Chinese College was set up in 1818 and was later moved to Hong Kong after it was ceded to Britain by the Treaty of Nanking in 1842. It was during the Second World War that Malacca was overtaken by Japan for some years and it was after the War that Malaya (or ‗Malaysia‘) declared her independence by uniting all the states on the Malay Peninsula in 1957 [3]. Furthermore, in order to unite and get control over this religiously pluralistic country, the new Malaysian government claimed to uphold Islam as its state religion. Hence, Malaysia became an Islamic country. Robert Morrison—The First Protestant Missionary in China Robert Morrison was the first Protestant Missionary who arrived on the Chinese Mainland in 1807. How did he come to know about China? When Morrison was preparing himself for missionary work in London, he came across the text of a Chinese translation of the New Testament Bible in the British Museum Library. He was surprised to find that Chinese characters were so sophisticated and beautifully written. Therefore, amongst other places, he chose China as his missionary field. His request was accepted by the London Missionary Society, but Morrison could not go directly to China. He was rejected by the British merchants. Being well aware of the Chinese (Qing) government‘s ‗closed-door policy‘, which would not allow any foreign missionary to enter the Chinese territories at that time, the British merchants simply refused to take him on board. Therefore, Robert Morrison took the route via New York in America and then boarded a ship, The Trident, from New York to China. This was indeed a global journey for Morrison, travelling from Europe to America, finally arriving at China in Asia on September 4 1807. Upon arrival in China, Morrison discovered that he really could not enter the Chinese Mainland as a missionary, so he worked as a translator for the British East India Company and lived in Canton and Macau on the southern coast of China ([6], pp. 62–136). For the first ten years, Morrison focused his time on learning the Chinese language and culture, and started compiling an English-Chinese dictionary, alongside with his translation work of the New Testament Bible ([7], pp. 38–45). The work as a translator and an interpreter helped not only to guarantee Morrison‘s stay in China, but also to improve a lot his understanding of the Chinese language and culture, which was an essential foundation for his translation of the Bible and his future ministry in China. The work was slow but steady. After ten years, Morrison submitted a report to the London Missionary Society, entitled: ―A Retrospect of the First Ten Years of the Protestant Mission to China‖ (dated 4 th September, 1817) ([6], pp. 243–245). Morrison admitted that the mission in China was not an easy one and that it was very slow progress. There was only one Chinese convert found, Religions 2012, 3 1079 named Tsae A-ko (蔡高), who was employed as a printing helper for Morrison. Tsae had been convinced by the work of Morrison and was finally baptized in October 1815, at the age of twenty-seven ([7], pp. 60–61). In his report, Morrison enclosed a proposal for ―The Ultra-Ganges Mission Plan‖. One of the proposals made was the setting up of a mission school in Malacca, the ―Anglo-Chinese College‖, which aimed at (1) the promotion of a better understanding of European and Chinese literature and culture; (2) the peaceful spread of the Christian faith and the East-Asian civilization throughout the globe ([6], p. 261; [8]). Why did Morrison choose to set up the Anglo- Chinese College at Malacca, awaiting the opening of China? [8] Though Morrison could not preach to the Chinese on the Mainland, he was convinced that since China was a civilized country, the best means of evangelization was through the understanding of Chinese language and culture. After ten years in preparation, Morrison had equipped himself with proper understanding of Chinese language and culture and he now found a Chinese community in Malacca who could read and speak in Chinese. They could be a perfect target group for evangelization of the Chinese people outside China ([6], p. 244). Hence, he started the Anglo-Chinese College there. As he stated, the aim of the College was to promote a better understanding of European and Chinese language and literature, to cultivate mutual dialogues between the two cultures, and to pave ways for the peaceful spread of the Christian faith and the East-Asian civilization around the globe ([6], pp. 222, 261). He had a vision of seeing the college as the ‗school for open minds‘, and Malacca to be not only the ‗Athens of the East‘, but also the ‗Jerusalem of the East‘ ([6], p. 264). It is interesting to note that even in the early 19 th century, Protestant missionaries like Robert Morrison had already entertained such ideas of respecting ‗heathen‘ cultures and working to promote better understanding of different cultures through the study of their languages and literatures. Morrison had made significant contribution in promoting the study of Chinese literature and culture at the Anglo-Chinese College. There were altogether seven Presidents of the College from 1818 on, until the year 1843 when the College was moved to Hong Kong. The seven Presidents were: William Milne (1818–1822) James Humphrey (1822–1824) David Collie (1824–1828) Samuel Kidd (1828–1832) Jacob Tomlin (1832–1834) John Evans (1834–1840) James Legge (1840–1843) Of the seven Presidents, some were so interested in the study of Chinese language and culture that they later became great Professors of Chinese Studies in well-known universities. For instance, David Collie had completed the translation of The Four Books (《四書》) in 1827 while he was still the President. Samuel Kidd was later appointed as the first Professor of Chinese at the University of London in England. He had trained a great number of students as Sinologists while he was a professor in London. One of his students was James Legge who followed his path and became the seventh President of Anglo-Chinese College at Malacca in 1840. James Legge was well-known for his translation and commentary work on The Four Books (《四書》) and The Five Classics (《五經》), which are still reckoned as authoritative commentaries of Chinese Classics nowadays ([9]; [10], p. 21). Religions 2012, 3 1080 James Legge was later appointed as Professor of Chinese Studies at Oxford University, England and had trained a great number of students to be Sinologists in the late 19 th and early 20 th centuries. As for the training of Chinese students, there were two known Chinese preachers, Leung Fat (Liang Fa, 1789–1855) and Ho Fuk Tong (Hoh Fook Tong, 1789–1855) worth to mention here. They were among the first ordained evangelists and pastors who had made significant contribution to the spread of Christianity in 19 th century China. Leung Fat had helped print the first complete Chinese Bible, which was jointly translated by Robert Morrison and William Milne. He had also written a number of Christian books and pamphlets, one of which was Quan Shi Liang Yan (‗The Benevolent Words to Advice the World‘). The pamphlet had inspired a young scholar, Hong Xiu Quan (1814–1864), who eventually established the ‗Tai Ping Heavenly Kingdom‘ (or known as ‗Tai Ping Rebellion‘) in China in 1851 [11]. The other student, Rev. Ho Fuk Tong was the second Chinese minister ordained by the London Missionary Society in China. He was put in charge of the Union Church in Hong Kong, which had played a significant role in society too ([12], pp. 6–13). James Legge had brought four students to United Kingdom and they became the first group of Chinese students to visit Buckingham Palace and were the guests of the Queen ([10], p. 23). There was another school, the Morrison School, which was set up in 1836, to commemorate the death, and continue the work, of Robert Morrison ([10], pp. 24–28). The president, Samuel R. Brown had brought 3 of his students to the United States in 1847—Yung Wing (Rong Hong 1828–1912), Wong Fun (Huang Kuan 1829–1878), and Wong Shing (Huang Xing 1827–1902). Yung Wing became the first Chinese student to graduate from an American university (Yale College) in 1854. Yung became a lifelong supporter of reform in China. He successfully persuaded the Qing government to send young Chinese students to the U.S. to study Western sciences and technology. During 1872–1875, he brought, altogether, 120 young Chinese students to the U.S. and these students made significant contribution to the modernization of China in the early 20 th century. Yung received an honorary Doctor of Laws from Yale University in its bicentenary in 1876 ([13], p. 83; [14], p. 9). The other student, Wong Fun, moved to the United Kingdom after studying for one year at Monson Academy in Massachusetts, and became the first Chinese student to attain a MD qualification as a physician and received a Ph.D. in Medicine from Edinburgh University. Another student, Wong Shing attended Monson Academy for one year and returned to China (Hong Kong) because he had been ill since arriving America. He later became the first Chinese juror in Hong Kong and succeeded Ng Choy as the second senior Chinese member of the Legislative Council in Hong Kong (1884–1890) ([10], pp. 24–28). It was also recorded that in 1823 Malacca‘s Anglo-Chinese College had already stored a collection of 3380 book volumes, of which 2850 were in Chinese and the rest were in European and other Asian languages. Hence, the College would probably be the first Asian Studies research centre in the Far East ([10], p. 18). The Anglo-Chinese College was moved to Hong Kong in 1843 and later continued with a new English name, ‗Ying Wa College‘, while the Chinese name ― 英華書院‖ remained unchanged. The school building has been moved to various places and is presently located at Shum Shiu Po, Kowloon, Hong Kong [15]. Religions 2012, 3 1081 Conclusion: Globalization and Religion In the article, ―The First Globalization: The Internationalization of the Protestant Missionary Movement between the World Wars‖, Dana Robert, an American historian, has reminded us that the Christian missionary movement could be seen as ―the first globalization‖ ([16], pp. 50–67). She argued that Christian missionaries were among the first group of people who had attempted global visions in spreading the Christian gospel and Christian culture to the world, or in their own terminology, ‗the evangelization of the whole world in this generation‘ ([17], p. 504). Indeed, besides Christianity, other religions such as Hinduism, Buddhism and Islam did share similar global visions and spread their religions in similar ways. Hence, they had also contributed greatly to the processes of globalization, especially in the Far East and in Southeast Asia. The history of Malacca and the story of Robert Morrison were really good cases for the study of the significant role of religion in the context of globalization of cultures. In the case of Malacca, religion was indeed a great moving force in such processes of globalization. It was the sending out of missionaries by the Indian Emperors that led to the spread of Hinduism and Buddhism, together with Indian rituals and cultures to the Far East and Southeast Asia. Religion as culture went hand in hand with commerce and politics, and they could not accomplish their work of evangelization so effectively and rapidly without the help of military forces. The coming of the Muslims was found even more vivid when it was seen from a global perspective. It was because of their defeat in Europe by the Christian Crusades that the Muslims were forced to turn to the Far East. The Muslims continued their conquest in Southeast Asia and ruled over Malacca for over a century. The Islamic culture was so imposing that the Malay people had incorporated much of it into their own culture. The religion was even claimed by the Malay Government as its state religion during its independence and Malaysia became an Islamic country. On the other hand, Christianity, whether it was Roman Catholicism, which came in the 16 th and 17 th centuries, or Protestantism, which came in the 19 th and 20 th centuries, had also brought its Christian gospel and Christian cultures to Malacca. However, since they were the ‗late-comers‘ in the state, they became ‗cultural otherness‘ in the non-Christian world in Asia. Peter Beyer, the Canadian sociologist of religion, has suggested this concept of ‗the factor of cultural otherness‘ in his study of globalization and religion ([18], p. 367). When Christian missionaries first came to Malacca as a non-Christian world, they had already identified the local Asian cultures as ‗heresy, heathendom and superstition‘, but very soon they were shocked to find that the Asian cultures—whether they were Indian, Chinese or Malay cultures, or whether they were Hindu, Buddhist or Islamic—were equally civilized and deserved to be respected as ‗cultures‘ too. In the same article, ―De-centering Religious Singularity: the Globalization of Christianity as a Case of Point‖, Beyer raised the issues of authority, orthodoxy, authenticity and legitimacy when Christianity experienced the process of globalization, especially in the 19 th and 20 th centuries. As he saw it, the ‗de-centring of Christianity‘ was expressed in the ‗loss of centralized authority‘ and ‗the separation of religious authority from religious authenticity and legitimacy‘ ([18], p. 369). In other words, global Christianity spawned multiple localizations and particularizations of religion, with the question of religious authority largely divorced from that of authenticity and legitimacy. Hence, Global Christianity had to pay due respect to all local cultures, whether they were European culture, American culture, Asian culture or Chinese culture [19]. Several Religions 2012, 3 1082 of his theses could be found vividly relevant in the case of Robert Morrison and throughout the history of Malacca. For instance, Morrison took a global route to China and arrived in China in 1807. Being a Protestant missionary, he had to learn to move between cultures, not only the crossing between lands and continents, from Europe to North America, then to Asia; or from Great Britain to the United States, then to China. It was also a crossing between cultures, from Western cultures to Asian and Chinese cultures. When Morrison came to Canton, he was not allowed to enter the city as a missionary and he had to respect the local culture. Hence, he worked as an interpreter for the British East India Company and settled to live between Macau and Canton. Morrison began to learn to build bridges between cultures. He started learning Chinese language and Chinese culture, and began to equip himself to be a good interpreter of Chinese culture and a good translator of the Bible into Chinese. He completed The Lord’s Prayer in Chinese Characters (《中文主禱文》) and The Holy Bible (《神天 聖書》). He had written a textbook, A Grammar of the Chinese Language (《中國語文凡例》), together with A Dictionary of the Chinese Language (《華英字典》) [20]. It was in such encounter with Chinese language and culture that Morrison had learned to understand the language and to pay due respect to Chinese culture. He had also found that ‗translation work‘ was not merely a mechanical arrangement of words, but it involved a deeper understanding of cultural and historical contexts, especially when one was dealing with the Chinese language and culture ([21], pp. 1–8; [22], pp. 65–83). Morrison had probably learned it so well that later, when he made a proposal to set up the Anglo-Chinese College in Malacca, he set a dual purpose for the college: ‗Firstly, (it was) to promote two-ways communication between Chinese and European languages and literatures, so that Europeans may be able to learn more about Chinese language and cultures and the Chinese may learn more English and about European cultures; Secondly, to help the peaceful spread of Christianity and East- Asian civilizations‘ ([7], pp. 164–165). In other words, ‗Education‘ was not merely the learning of a language, but also its culture and literature. In addition, ‗Communication‘ must travel two ways, with teachers and students, Europeans and Chinese, both learning from one another at the same time. Hence, what could missionaries do in the process of globalization? It was the building of bridges so that through this ‗two way‘ education, both teachers and students could cross the bridges and enter into communication and dialogue between the two cultures; therefore, they were mutually educated. The term ‗Anglo-Chinese‘ was indeed a great invention. What Robert Morrison attempted to do was the building of bridges, which would link the two cultures together. As a result, the Anglo-Chinese College had produced not only great Chinese scholars who were well-versed with European cultures, but also many great Sinologists for the West, including the two college presidents: Samuel Kidd, who had became the First Professor of Chinese at University of London; and James Legge, who became a Professor of Chinese Studies at Oxford University in England. Both had contributed significantly in the processes of cultural globalization in the past centuries ([10], pp. 18–22; [23], pp. 3–11). In short, the history of Malacca demonstrates clearly the importance of the religious factor in the process of globalization in Southeast Asia, and the missionary work of Robert Morrison has shown how Protestant missionaries learned to respect local cultures, especially Chinese culture in this case, which remained a crucial factor both in the re-thinking of the significant roles played by religion in the process of cultural globalization and also in the conception of the interplay between globalization and religion as we think of it today. Religions 2012, 3 1083 References 1. Beyer, Peter. Religions in Global Society. London: Routledge, 2006. 2. Beyer, Peter, and Lori Beaman, eds. Globalization, Religion and Culture. Leiden, Netherland: Koninklijke Brill, NV, 2007. 3. Batumalai, Sadayandy. A History of Christ Church Melaka of the Diocese of West Malaysia in the Province of S.E. Asia. Melaka, Malaysia: Syarikat Percetakan Muncul Sistem Sdn. Bhd, 2003. 4. Luis Filipe Ferreira Reis Thomaz. ―The Malay Sultanate of Melaka.‖ In Southeast Asia in the Early Modern Era- Trade, Power and Belief, edited by Anthony Reid. Ithaca, N.Y.: Cornell University Press, 1993, chapter 3, pp. 69–90. 5. Lee Su Kim. ―The Peranakan Baba Nyonya Culture: Resurgence or Disappearance?‖ Sari 26 (June 2008): 161–70. 6. Morrison, Eliza Armstrong. Memoirs of the Life and Labours of Robert Morrison, D.D. (1839) Chinese translation by Joe Dunn. Hong Kong: Chinese Christian Literature Council Ltd., 2007. 7. Milne, William. A Retrospect of the First Ten Years of the Protestant Mission to China (1817). Chinese translation by Zhengzhou: Da Xiang Publishing Co. 2008. 8. Brian Harrison, Waiting for China: The Anglo-Chinese College at Malacca, 1818–1843. Hong Kong: Hong Kong University Press, 1979. 9. James Legge. The Chinese Classics (in 5 volumes). Hong Kong: Hong Kong University Press, 1960. 10. Ng, Peter Tze Ming. ―Earliest Protestant Missionary Schools since the 19th Century (In Chinese).‖ In Christianity and University Education in China. Beijing: China Social Sciences Press, 2006, 16–28. 11. Spence, Jonathan D. God's Chinese Son: The Taiping Heavenly Kingdom of Hong Xiuquan. New York: W.W. Norton, 1996. 12. Cha, Shijie. Zhongguo Jidujiao renwu xiaochuan (Biographies of Christian characters in China). Taipei: China Evangelical Seminary Press, 1983. 13. Yung, Wing. My Life in China and America. New York: Henry Holt & Co., 1909, 16–28. 14. Chu, T. K. ―150 Years of Chinese Students in America.‖ Harvard China Review, Spring 2004, 1–9. 15. Lau Siu Lun. Sanctuary of Excellence: The History of Ying Wa College. Hong Kong: The Alumni Association of Ying Wa College Co. Ltd., 2001. 16. Robert, Dana L. ―The First Globalization: The Internationalization of the Protestant Missionary Movement between the World Wars.‖ International Bulletin of Missionary Research 26 (2002): 50–67. 17. See Latourette, K.S. Christianity in a Revolutionary Age: A History of Christianity in the 19 th and 20 th Centuries. Grand Rapid: Zondervan Publishing House, 1962, vol. 5. 18. Beyer, Peter. ―De-centring Religious Singularity: The Globalization of Christianity as a Case in Point.‖ Numen 50 (2003): 357–386. 19. Ng, Peter Tze Ming. Chinese Christianity: An Interplay between Global and Local Perspectives. Leiden & Boston: Brill Publishing Co., 2012. 20. Morrison, Robert. A Dictionary of Chinese Language. Macau: East Indian Company Press, 1815– 1823, 6 volumes. http://en.wikipedia.org/wiki/Jonathan_D._Spence Religions 2012, 3 1084 21. Lamin O. Sanneh. Translating the Message: The Missionary Impact on Culture. New York: Orbis Books, 1989. 22. Zhong, Shao Hua. ―A Study of Morrison‘s Dictionary of Chinese Language: Using the Word ‗Learning‘ as a Case.‖ In East Meets West: Essays Celebrating the Bicentennial of Protestant Christianity in China, edited by Lee Kam Keung et al. Hong Kong: Chinese Christian Literature Council Ltd., 2009, 65–83. 23. Leung, Philip Yuen Sang. ―Crossing Oceans and Building Bridges: A Study of Morrison‘s Experience in China from Cultural Perspectives (In Chinese).‖ In East Meets West: Essays Celebrating the Bicentennial of Protestant Christianity in China, edited by Lee Kam Keung et al. Hong Kong: Chinese Christian Literature Council Ltd., 2009, 3–13. © 2012 by the author; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). work_a4dezi2ql5aphag37jqg5qbqmm ---- 3037 More anthropogenic CO2 in deep ocean than previously thought 3273 Little role for competition in regulating population size 3289 Barley domesticated twice 3663 Isotope analysis details Columbus’ second expedition failure ENVIRONMENTAL SCIENCES More anthropogenic CO2 in deep ocean than previously thought Carbon dioxide (CO2) produced by human activities (anthropo- genic CO2) is a key driver of global climate change. Roughly half of the CO2 generated from the burning of fossil fuels is stored in the oceans, and changing oce- anic carbon concentrations can be indicators of human- generated CO2. Estimating anthropogenic CO2 levels in the oceans has been challenging due to natural variability, the need to estimate preindustrial oce- anic carbon levels, and the different behavior and properties of ‘‘proxies,’’ or indirect indicators of CO2, such as chlorof luorocar- bons. To avoid these problems, Toste Tanhua et al. developed and applied a method to estimate anthropogenic oceanic CO2 in the North Atlantic Ocean, based on measurements of decadal changes in ocean carbon concentrations. The authors determined that an- thropogenic CO2 levels in the deep ocean are higher than previous estimates. These higher CO2 levels could imply a longer-lived ca- pacity of the ocean to act as a carbon sink for the future, but could also show potential for negative impact on calcification by deep-water corals and other organisms. — M.M. ‘‘An estimate of anthropogenic CO2 inventory from decadal changes in oceanic carbon content’’ by Toste Tanhua, Arne Körtzinger, Karsten Friis, Darryn W. Waugh, and Douglas W. R. Wallace (see pages 3037–3042) ECOLOGY Little role for competition in regulating population size Population ecologists have long debated whether population sizes are driven primarily by competition for scarce resources or by en- vironmental factors such as precipitation or temperature. If com- petition is the primary driver of population size, changes in the abundance of one species should be accompanied by compensa- tory changes in the abundance of other species within a commu- nity; that is, there should be a negative covariance. To assess the role of such ‘‘compensatory dynamics’’ on population size, J. Hou- lahan et al. analyzed the amount of covariance in 41 different plant and animal communities throughout the United States and United Kingdom. In these natural communities, species tended to vary positively, contrary to the negative covariance predicted by compensatory dynamics. These results suggest that environmental factors are more important than competition among coexisting species in driving the yearly f luctuations in species abundance within a given community. — M.M. ‘‘Compensatory dynamics are rare in natural ecological communi- ties’’ by J. E. Houlahan, D. J. Currie, K. Cottenie, G. S. Cumming, S. K. M. Ernest, C. S. Findlay, S. D. Fuhlendorf, U. Gaedke, P. Legendre, J. J. Magnuson, B. H. McArdle, E. H. Muldavin, D. Noble, R. Russell, R. D. Stevens, T. J. Willis, I. P. Woiwod, and S. M. Wondzell (see pages 3273–3277) EVOLUTION Barley domesticated twice Since Neolithic times, barley (Hordeum vulgare) has been an important crop, found at human Neolithic sites in Palestine and Syria dating back to 8500 B.C. The grain has also been cultivated for at least 8,000 years in Central Asia, but whether it was domesticated locally or imported from the Middle East remains un- known. Peter Morrell and Michael Clegg show that two independent domestications of barley occurred. The first event occurred within the Fertile Crescent, and the sec- ond occurred 1,500 –3,000 km further east. The authors used DNA sequencing and genetic assignment analysis to examine �60 wild and domesticated barleys. Ten SNPs exclusive to wild and domesticated barley cultivars from east of Iran’s Zagros Mountains were identi- fied, and a number of haplotypes was associated with a ge- netic divide between western barley strains and wild barley found east of the Zagros Mountains. Today, most of the di- versity seen in European and American barley cultivars stemmed from the Fertile Crescent domestication, whereas Concentration of anthropogenic carbon in North Atlantic Ocean. Wild barley in Syria. www.pnas.org�cgi�doi�10.1073�iti0907104 PNAS � February 27, 2007 � vol. 104 � no. 9 � 3017–3018 PNAS Proceedings of the National Academy of Sciences of the United States of America www.pnas.org In This Issue February 27, 2007 � vol. 104 � no. 9 � 3017–3668 D o w n lo a d e d a t C a rn e g ie M e llo n U n iv e rs ity o n A p ri l 5 , 2 0 2 1 most of the diversity seen in barley cultivars from central Asia and the Far East originated from the second domestica- tion event. — B.T. ‘‘Genetic evidence for a second domestication of barley (Hordeum vulgare) east of the Fertile Crescent’’ by Peter L. Morrell and Michael T. Clegg (see pages 3289 –3294) ANTHROPOLOGY Isotope analysis details Columbus’ second expedition failure In 1494, Christopher Columbus established La Isabela, the first European settlement in the New World, on the Domini- can Republic’s north coast, with the aim of discovering and exploiting gold and silver ores. The site was abandoned in 1498, but recent archaeological finds of crucibles, metallurgi- cal slag, and silver-bearing galena seemed to indicate that the expedition had found local sources of precious metals. Alyson Thibodeau et al. report, however, that the lead isotope com- position of La Isabela’s galena does not match any known galena deposits in the Caribbean. Rather, the galena at La Isabela resembles galena de- posits found in Spain. Thi- bodeau et al. infer that these ores were brought over from Spain as a reagent for metal assays during early metal ex- ploration. In addition, most of the slag consists of lead silicate glass, which would be produced if the galena was refined using beach sand instead of the bone ash typi- cally employed in medieval European refining practices. Com- bining these findings with close scrutiny of the archaeological evidence, Thibodeau et al. suggest that La Isabela does not represent some of the first New World mining by Europeans, but rather a desperate attempt by the sur vivors of a failed expedition to extract metals from their own supplies. — N.Z. ‘‘The strange case of the earliest silver extraction by European colonists in the New World’’ by A. M. Thibodeau, D. J. Killick, J. Ruiz, J. T. Chesley, K. Deagan, J. M. Cruxent, and W. Lyman (see pages 3663–3666) Lead silicate glass slag from La Isabela. 3018 � www.pnas.org�cgi�doi�10.1073�iti0907104 D o w n lo a d e d a t C a rn e g ie M e llo n U n iv e rs ity o n A p ri l 5 , 2 0 2 1 work_a4s2yq3tjvevvm44o5ukvljqum ---- UC Santa Barbara UC Santa Barbara Previously Published Works Title The Boy Problem: Educating Boys in Urban America, 1870-1970 Permalink https://escholarship.org/uc/item/33g9c361 Journal AMERICAN HISTORICAL REVIEW, 120(1) ISSN 0002-8762 Author Chavez-Garcia, Miroslava Publication Date 2015-02-01 DOI 10.1093/ahr/120.1.258 Peer reviewed eScholarship.org Powered by the California Digital Library University of California https://escholarship.org/uc/item/33g9c361 https://escholarship.org http://www.cdlib.org/ for their ethnic origins, noting that their assimilation into mainstream American culture remains incomplete. He characterizes their culture as “American Italian.” Many of them still experience persistent prejudice. Some retain allegiance to their homelands by playing soccer and bocce; they take pride in their Italian her- itage, but identify themselves as more American than Italian. Gems observes that despite Italian achieve- ments in the political, economic, and social life of the United States, “Italian-American monuments are no longer dedicated to Christopher Columbus, or even to national leaders, statesmen or -women, or military he- roes, but to athletic heroes in the popular culture” (pp. 214 –215). Sport and the Shaping of Italian-American Identity is a clear and engaging summary of the experiences of the first four generations of Italians in the United States. Those who are familiar with this saga will find little orig- inal material in Gems’s volume, but they will gain new knowledge about how sport enabled newcomers from Italy to gain entry into mainstream American society while preserving the customs and traditions of their home regions and villages. Gems’s book has a few weak- nesses. It is repetitive, and includes too many digres- sions on the Italian experience in the United States. It also lacks depth on the cultural meaning of soccer and bocce for Italian-American players and spectators. But, on the whole it is a major contribution to a subject ne- glected by specialists in immigration history, and it will enlighten readers from the general public who enjoy learning more about Italian-American participation in and contributions to American sports. GEORGE B. KIRSCH Manhattan College JULIA GRANT. The Boy Problem: Educating Boys in Ur- ban America, 1870–1970. Baltimore: Johns Hopkins University Press, 2014. Pp. 230. $45.00. Julia Grant’s The Boy Problem: Educating Boys in Urban America, 1870–1970 came at an opportune moment when I struggled to understand why my eight-year-old son had difficulties in his fourth-grade class. Unable to sit for extended periods and complete his assignments on time, my son interrupted his peers and his teacher. Rather than linking my son’s problems to what Grant calls the current “moral panic” (p. 2) over bad boys of color, I learned that my son’s difficulties were, instead, tied to centuries’ old notions of acceptable and unac- ceptable behavior—in reality, learning styles—in and outside the classroom. Indeed, Grant’s book forces us to reconsider the ineffective and destructive ap- proaches in attempting to mold racially and ethnically diverse, migrant and immigrant, poor, working-class young boys into productive male citizens. She demon- strates that even when many European American boys in the early twentieth century had the opportunity to escape the clutches of poverty, prejudice, and the ghetto, entrenched racism, intimidation, and violence locked out African American boys from those same av- enues of social mobility, forcing them to occupy the cur- rent ranks of the “boy problem.” Today’s boy problem, she says, is a long-term “consequence of inadequate and punitive schools, poverty, race, ethnicity, and cul- tures of masculinity that emerge as an antidote to op- pressive social structures” (p. 1). Using a thematic and chronological approach, Grant’s study begins by exploring the evolution of mis- guided models for the socialization of the poor, immi- grant, ethnic, and working classes that emerged in the nineteenth century with the explosion of urban centers in the North. Spurred by massive immigration, indus- trialization, and urbanization, social reformers worried about the growing “dangerous classes” and illiteracy, lawlessness, and poverty found in the cities (p. 7). Rather than assisting parents, reformers established re- formatories, orphan trains, and public education aimed specifically at containing boys who they viewed as trou- blesome. Similar institutions for girls emerged, too, but on a smaller scale and they focused on containing sex- uality and inculcating domestic values, underscoring the gendered nature of social reform. The rise in anxieties and beliefs about the inherent, savage nature of boys, an ideology that emerged in the early twentieth century, led reformers to organize ath- letic programs and build boys’ clubs and recreation cen- ters, including the Young Men’s Christian Association (YMCA), to tame and channel boys’ energies into use- ful activities. Compulsory and special education also figured prominently in the social reformers’ approach to handle particularly wayward and problematic boys. To control and contain poor, unruly, and unsupervised boys who posed a moral menace to the larger society, reformers invented the crime of truancy, giving school officials the power to police the bodies of school-age boys in public spaces. In the classroom, reformers turned to the accepted practice of measuring intelli- gence to determine boys’ fitness in the standard edu- cational setting. Reformers then sent boys who scored poorly on the intelligence tests to classes for “back- ward” or “subnormal” children or, in extreme cases, to institutions for the defective and uneducable. The rigid and intolerant culture of the schools, Grant demonstrates, contributed to the development of de- structive peer cultures of delinquency in the early and mid-twentieth century. Robbed of opportunities to demonstrate their promise in the classroom, boys re- sisted schooling, performed poorly, and simply stayed away. To affirm their racial, ethnic, and gendered iden- tities, many of these boys joined gangs and devised al- ternative ways of expressing their masculinity. When child welfare workers sought to reorient such youths to the school setting, they misunderstood the larger con- text in which the boys and gangs operated. Focusing on tapping into the boys’ masculinity as a way to transform their behavior, welfare workers ignored the larger so- cial structures that confined them in and outside the classroom and, in the process, re-inscribed the same no- tions they sought to overturn. Finally, Grant focuses on African Americans, detail- 258 Reviews of Books AMERICAN HISTORICAL REVIEW FEBRUARY 2015 by guest on F ebruary 13, 2015 http://ahr.oxfordjournals.org/ D ow nloaded from http://ahr.oxfordjournals.org/ ing their experiences in the educational setting in the twentieth century, particularly in the 1940s and 1950s, when they came to the attention of the school author- ities in the wake of the Great Migration. Grant details how deeply entrenched racism prevented them from gaining a foothold in the educational system and, in- stead, funneled disproportionate numbers of them to special schools and reformatories. When community leaders brought race and the failure of the educational system to national attention, the focus was primarily on girls and not on boys’ poor school performance. In- stead, the gaze shifted to the boys’ participation in gangs. Grant closes her study with an examination of the most significant developments in special education and juvenile justice in the 1960s and 1970s. While new pol- icies and practices were developed to intervene in the lives of some of the most poorly performing school chil- dren, poor and racial and ethnic minorities, they were largely ignored in favor of mainstreaming and, later, inclusion of “special needs” children, not necessarily boys of color. Boys and boys of color, in particular, she concludes, continue to be overrepresented in special education and the juvenile justice systems. Grant’s study is successful for its engaging prose and ability to reach across a broad variety of fields, includ- ing education, juvenile justice, and childhood, youth, and gender studies, to delineate the interlocking his- tories of institutions of social control for young people and reveal the deeply entrenched ideologies of gender, class, ethnicity, and race that shaped their establish- ment and their development in the nineteenth and twentieth centuries. Though not her focus, the inclu- sion of Latino boys in her analysis would have brought new insight to understanding how social reformers’ fixed notions of gender, class, ethnicity, and race in the twentieth century served to disempower many, if not most, boys of color in classrooms throughout the United States today. This reviewer would have also wel- comed the discussion of African American boys’ expe- riences within each chapter rather than in a separate chapter at the end of the book, for it appears as an af- terthought, though this likely was not the intention. Ul- timately, she argues, we must transform how we think about boys’ and girls’ learning styles in the classroom as well as peer cultures of masculinity if we are to enable students of all backgrounds to reach their educational potential. MIROSLAVA CHÁVEZ-GARĆIA University of California, Santa Barbara ROBERT MACDOUGALL. The People’s Network: The Po- litical Economy of the Telephone in the Gilded Age. (American Business, Politics, and Society.) Philadel- phia: University of Pennsylvania Press, 2014. Pp. 332. $55.00. In an increasingly interdependent world, the expansion of transportation and communication networks to cover more territory and connect more people often seems natural and inevitable. As Robert MacDougall reminds us in this insightful comparative history of late- nineteenth and early-twentieth-century telephone net- works in the United States and Canada, however, the introduction of technologies of reach such as the rail- road, telegraph, and telephone has frequently been more contentious and contingent than is commonly perceived. Questions regarding access to and authority over telephone networks produced fierce commercial, political, and cultural battles in both countries. In the United States, they also generated the independent te- lephony movement, a viable alternative to the domi- nance of the American Telephone and Telegraph Com- pany (AT&T) and its predecessor, American Bell. One of MacDougall’s objectives is to uncover the dramatic but forgotten early history of the North Amer- ican telephone networks. The drama of those early years has been neglected, he argues, because AT&T has written or commissioned much of the published history of the telephone. Even independent scholars have re- lied heavily on the records in the AT&T archives. There is also a tendency in the history of technology to treat the most recent device or system as the most logical one and ignore the choices made along the way and possible alternative outcomes. Consequently, the history of the telephone has focused on the gradual expansion of AT&T’s high quality network across the nation. Mac- Dougall has scoured trade journals, the records of AT&T’s early rivals, and municipal archives to shed light on the independent movement and its “vision of ‘a telephone for the people’” (p. 4). The independents favored decentralized, locally owned and locally ori- ented telephone networks that offered less expensive but lower quality service to a broader swath of the pop- ulation. A second objective is to highlight the role of political economy in shaping technological outcomes. According to MacDougall, the key determinants in the develop- ment of the independent telephony movement were the involvement and relative power of municipal govern- ments. In areas where local government actively en- gaged the telephone industry, there was more compe- tition, wider and earlier access to telephone service, and a more frivolous culture of telephone use. In towns and cities without such municipal involvement, there was less competition, better quality but more expensive telephone service, and a more formal telephone cul- ture. MacDougall’s third objective is to compare the de- velopment of the telephone networks in the United States and Canada. In regions of the United States with active municipal governments, such as the Midwest and the West, independent telephony thrived. In 1907, “in- dependents controlled more than half of the six million telephones in the United States” (p. 2). In Canada, where Parliament regarded the telephone as a work for national benefit and cities had much less political power, municipal politicians accepted local monopo- lies. Ironically, the nationalist vision of the telephone in Canada ultimately undermined attempts to create a sin- Canada and the United States 259 AMERICAN HISTORICAL REVIEW FEBRUARY 2015 by guest on F ebruary 13, 2015 http://ahr.oxfordjournals.org/ D ow nloaded from http://ahr.oxfordjournals.org/ work_a7nnjyoqczevtaiauygocekmmi ---- R. Price Caribbean pepper-pot In: New West Indian Guide/ Nieuwe West-Indische Gids 58 (1984), no: 1/2, Leiden, 89-98 This PDF-file was downloaded from http://www.kitlv-journals.nl Downloaded from Brill.com04/06/2021 01:09:21AM via free access REVIEW ARTIGLES CARIBBEAN PEPPER-POT Amerindians of the Lesser Antilles: a bibliography. R O B E R T A. M Y E R S . New Haven CT: Human Relations Area Files, 1981. x + 158 pp. (Paper US$ 15.00) Santo Domingo en los manuscritos de Juan Bautista Munoz- R O B E R T O MARTE (ed.). Serie Documental Vol. I. Santo Domingo, Dominican Republic: Ediciones Fundación Garcia Arévalo (P.O. Box 723, Santo Domingo), 1981. xxxix + 573 pp. (Cloth US$ 15.00) Crónicas francesas de los indios caribes. Edited and translated by MANUEL CARDENAS Ruiz. Rio Piedras, Puerto Rico: Editorial Universidad de Puerto Rico and Centro de Estudios Avanzados de Puerto Rico y el Caribe, 1981. xii + 624 pp. (Paper US$ 20.00) Race and ethnic relations in Latin America and the Caribbean: an historical dictionary and bibliography. ROBERT M. LEVINE. Metuchen NJ: The Scarecrow Press, 1980. viii + 252 pp. (Gloth US$ 14.50) Dictionary of Afro-Latin American civilization. BENJAMIN N U N E Z , with the assistance of the African Bibliographic Center. Westport CT: Greenwood Press, 1980. xxxv + 525 pp. (Cloth US$ 45.00) The Jamaican national bibliography 1964—igj4- INSTITUTE OF JAMAICA, KINGSTON. Millwood NY: Kraus International, 1981. viii + 439 pp. (Cloth US$ 120.00) Downloaded from Brill.com04/06/2021 01:09:21AM via free access g o REVIEW ARTICLES Towards a bibliography of African-Caribbean studies igjo-ig8o. BEVERLEY HALL-ALLEYNE, GARTH WHITE, MICHAEL COOKE (eds.). Kingston, Jamaica: African-Caribbean Institute of Jamaica, 1982. ii + 37 pp. (Paper n.p.) Les migrations antülaises: bibliographie sélective et annotêe. M A R I A N N E KEMPENEERS & RAYMOND MASSÉ. Montréal: Centre de Recherches Caraïbes de l'Université de Montréal, 1981. 53 pp. (Paper n.p.) Latin America: a guide to illustrations. A. CURTIS W I L G U S . Metuchen NJ: The Scarecrow Press, 1981. xxviii + 250 pp. (Cloth US$ 16.00) Encyclopaedie van Nederlandsen West-Indië. H . D. BENJAMINS & J O H . F. SNELLEMAN (eds.) Unchanged reprint of the original edition, The Hague-Leiden, 1914—191 7. Amsterdam, S. Emmering, 1981. xi + 782 pp. (Cloth Dfl. 65.00) Dutch authors on West Indian history: a historiographical selection. M. A. P. MEILINK-ROELOFSZ (ed.), translated by MARIA J. L. VAN YPEREN. Koninklijk Instituut voor Taal-, Land- en Volkenkunde Translatiori Series 21. The Hague: Martinus Nijhoff, 1982. viii + 384 pp. (Paper Dfl. 95.00, US$ 41.50) The Jewish nation in Surinam: historicalessays. R O B E R T C O H E N (ed.). Amsterdam: S. Emmering, 1982. 103 pp. (Paper Dfl. 65.00) Metamorphosis insectorum Sunnamensium of de Verandering der Suri- naamse insecten: metamorphosis of the insects of Surinam. M A R I A SIBYLLA MERIAN. Edited by CHRIS SCHRIKS, with translations by P. A. VAN DER LAAN. Zutphen: De Walburg Pers, 1982. Unpagi- nated. (Cloth Dfl. 69.50) De wisselende gedaante: facetten van Maria Sibylla Merian. J . E. V . D . LAAN. Zutphen: Uitgeverij Terra, 1980. 46 pp. (Paper n.p.) Reis door Suriname: beschrijving van de Nederlandse bezittingen in Guyana. Downloaded from Brill.com04/06/2021 01:09:21AM via free access REVIEW ARTICLES g i P. J. BENOIT. Translated and edited by CHRIS SCHRIKS, with an English summary by SILVIA W. DE GROOT. Zutphen: De Walburg Pers, 1980. 99 pp. + 99 colored plates. (Cloth Dfl. 95.00) Avonturen aan de Wilde Kust: de geschiedenis van Suriname met zijn buurlanden. ALBERT HELMAN. Alphen aan den Rijn: A. W. Sijthoff, 1982. 208 pp. (Cloth Dfl. 52.50) The current sampling of reference tomes — intended to complement those in Price 1980 and 1982 — resembles that pinnacle of aboriginal Caribbean cuisine, the pepper-pot: for it, too, "is a compound of the most heterogeneous description" (Cassidy & Le Page 1967: 346), sometimes "palate-scorching," sometimes "delicate," "a kind of devil's broth" (OED, s.v. Pepper-pot), something to dip into time and again, with a some- what different flavor on each occasion, since new ingredients are added to the pot each day. Recent works devoted to Caribbean Amerindians seem a fitting starting place. Myers' workmanlike bibliography is easily the most comprehensive available guide to its subject, with some 1300 unannotated references by nearly 500 authors (vs. about 200 comparable references in Comitas' Complete Caribbeana). The author, a social anthropologist whose own research has been with the Carib of Dominica, carried out archival and library visits in Jamaica and London as well as in major U.S. repositories, to produce six alphabetical listings, divided into Archaeology and Prehistory; Archives, History, Travel and Description, and Social Science Research; Languages; Biology, Nutrition and Medicine (very brief); and Literature (also very brief). There are both geographical and authors' indexes, as well as a thoughtful Preface. Myers' work provides a focused and selective counterpart to the more ambitious but far spottier pan-Caribbean Amerindian bib- liography compiled by Sued Badillo (1977); that earlier work does, however, include a significant number of items on the Lesser Antilles not in Myers', and the two might usefully be consulted together. Marte's impressive compilation of early manuscripts on Santo Domingo will be welcomed by a broad range of Caribbean his- Downloaded from Brill.com04/06/2021 01:09:21AM via free access g2 REVIEW ARTICLES torians and anthropologists. Drawn from the magnificent Colección Munoz in the Real Academia de la Historia in Madrid — Mufioz: was the eighteenth-century historian who founded the Archivo General de Indias and whom Carlos III designated Cosmógrafo Mayor de Indias — these varied documents (includ- ing maps and other illustrations) span the years from Columbus' second voyage to the mid-sixteenth century. Marte provides a helpful historiographical introduction, careful annotations, a glossary, and indexes. This first volume is a most auspicious beginning for the new documentary series from the Fundación Garcia Arévalo, which has been so active in recent years in publishing archaeological, historical, and ethnographic works on the Dominican Republic. Crónicas francesas, which has a comprehensive ninety-page Introduction by Ricardo Alegria, offers a judicious selection of seventeenth-century French witnesses to the Carib world, with readable Spanish translations and careful notes by Cardenas Ruiz. Samplings from the well-known works of Rochefort, Du Tertre, de la Borde, and Labat are complemented by those of such lesser-known observers as Du Puis, Chevillard, and Coppier, and contemporary engravings are scattered through the text. Overall, this is an attractive book and another significant step in bridging insular and linguistic boundaries; it should be welcomed by stu- dents throughout the hispanophone Caribbean. The two recent "dictionaries" — one on Afro-Latin American civilization, the other on race and ethnic relations — contrast dramatically in quality and potential usefulness. Levine's book is almost an affront to scholars, librarians, and the people whose lives it documents, and should never have been published. The effect of reading its individual definitions is cumulative; the com- bination of errors, misinformation, and idiosyncratic selectivity truly boggled this reader's mind. From its remarkable definition of "Negro": "One of the major races of mankind, characterized by slight body hair, small ears, wooly or frizzed head h a i r . . . , " it goes straight downhill: the interested reader might try, at random, the entries s.v. "Jewish Maroons," "Talkie-Talkie," "FESTAF," "Compadrazgo," "Chichicastenango Drunkenness," or "Racial Endogamy," and decide whether the appropriate response is to Downloaded from Brill.com04/06/2021 01:09:21AM via free access REVIEW ARTICLES 9 3 laugh or to cry. Nufiez' more substantial dictionary (4,500 en- tries) contains a good deal of mainly accurate, if necessarily selective, information. A side-by-side comparison with Levine's work (s.v., for example, Abeng, Beké, Bozal) quickly reveals the contrasting quality of their definitions. Nevertheless, such a dic- tionary — one volume, largely single-authored — must remain so selective that its usefulness seems limited largely to beginning students. Considering the genuine richness of more geographi- cally focused dictionaries such as that by Cassidy & Le Page for Jamaica (1967) or Holm & Shilling on the Bahamas (1982), or of Herdeck's encyclopedie work on Caribbean writers (1979), one might question whether a book that very selectively sprinkles, for example, writers and root crops amidst Afro-Brazilian cults and Jamaican proverbs is ultimately worth the very serious efforts and expense that went into its production. The Jamaican National Bibliography, 1964— igy4 is a somewhat problematical, if handsomely printed and bound, endeavor. For its core is the "Jamaican" portion of the West India Reference Library, Institute of Jamaica, covering items acquired and catalogued between 1964 and 1974. Yet its publisher, Kraus International, brought out in 1980 a six-volume comprehensive catalogue of that same library, explicitly including all items catalogued through 1975. It seems curious that this latest volume not only includes a significant number of items not in the larger set (explicable, in part, because the new one covers the relevant holdings of several additional local repositories) but also lacks many apparently relevant items from the former collection. In any case, the entries in the newer, more specialized publication have been carefully printed and proofread, in contrast to the photo-offset uncorrected card-catalogue approach of the larger work (see Mintz 1982, Price 1982). The idea of an ongoing national bibliography for Jamaica is certainly laudable; the apparent lack of coordination of bibliographical endeavors even within one Caribbean state must, however, be deplored. At the opposite financial end of the reference book production continuüm, the African-Caribbean Institute of Jamaica has issued a modest, mimeographed checklist covering the last decade of African-Caribbean studies. Divided into General Works, Art, Downloaded from Brill.com04/06/2021 01:09:21AM via free access 9 4 REVIEW ARTICLES Family Structure, Religion, and so on, it is a necessarily prelimi- nary compilation that is, nonetheless, guaranteed to add at least a few unknown items to the bibliographic knowledge of even the most knowledgeable Afro-Americanists. May this kind of spe- cialized, labor-intensive bibliographic work continue! Les migrations antillaises is an annotated, very selective biblio- graphy that will prove useful to beginning researchers interested in the geographical movement of Caribbean peoples. Thirty- three references about migration to Canada are followed by twenty-seven on the U.S., thirty-three on Europe and fifty-six on internal and return migration. The academie subject matter, like the social facts it addresses, continues to experience runaway growth, and a fuller bibliographic survey would now be most welcome. The Guide to Latin American (and Caribbean) illustrations, according to its author, "fills a gap in publications in English relating to Latin America by providing an aid for a better under- standing of the rise and development of these countries" (v), and he considers it a supplement to the twenty-three historical diction- aries to which Levine's work belongs. It is, unfortunately, a fitting supplement to that publishing venture. For Wilgus' own dis- claimers about incompleteness and limitations do not begin to signal the volume's fatuousness. What reader — student, scholar, librarian, general reader — would benefit from consulting the pictorial references he chooses to cite? Consider these complete examples, from the Dutch, British, and French Caribbean: the full listing under "Bush Negroes" (surely one of the most photo- graphed of all Caribbean populations) consists of a 1954 Américas article and a single plate from a general book on South America; under "Dominica" one also finds but two sources, the twenty- volume Peoples of the earth encyclopedia and a plate labelled "water fall"; and for the picturesque island of Martinique there are but the following five sources (fully representative of the kinds of sources throughout the volume) — The tropics, Peoples of the earth, The West Indian islands, Christopher Columbus, and the National Geographic. Compiling a successful guide to Latin American il- lustrations would be a massive enterprise, one that new tech- nology could bring within the reach of the team of knowledgeable Downloaded from Brill.com04/06/2021 01:09:21AM via free access REVIEW ARTICLES 9 5 specialists, from different countries, that would be necessary to accomplish it. The present volume, to which the author appar- ently devoted considerable labor, seems a thoroughly misguided effort. The Encyclopaedie van Nederlandsen West-Indië, written more than six decades ago, represents to my mind the pinnacle of Dutch colonial scholarship on the Caribbean. The publication by teams of modern experts of an Encyclopedie van de Nederlandse Antillen in 1969 and an Encyclopedie van Suriname in 1977 in no way detracts from the achievement or continued usefulness of many of the articles in the original volume; it remains a major storehouse of historical, geographical and biographical information. S. Emmering deserves our thanks for continuing to make available once again important historical sources on the history of the Netherlands West Indies and Suriname. Two other volumes make traditional Dutch scholarship on the Caribbean available for the first time to an English-speaking audience. Meilink-Roelofsz provides a forthright, informative guide to Dutch historiography on "the West" during the first half of the twentieth century. The authors — many of whom will be familiar to readers of this journal — include, in addition to the editor, Bijlsma, Unger, van Winter, van Hoboken, van Dillen, van Overeem, Knappert, de Gaay Fortman, Kesler, and van Grol. The historiographical record, as she describes it and as the translated articles clearly attest, is far from overwhelming — Dutch colonial historians gave relatively little attention to their Caribbean possessions until very recent decades, and the selec- tions she had to choose from were in many respects disappointing. But this is an honest and representative sampling, made more useful by the introduction and biographical notes. Cohen's selec- tion of historical essays on the Jews of Suriname vombines more traditional with modern scholarship: four previously published pieces (by van Lier, Bijlsma [the same article that appears in Meilink-Roelofsz], Rens, and Schiltkamp) and three new ones, all presented here in English. Together they constitute a brief, some- what miscellaneous introduction to an important corner of Carib- bean history. There is a faintly hagiographic tone to parts of the book, with more stress on the Enlightenment values and learning Downloaded from Brill.com04/06/2021 01:09:21AM via free access g 6 REVIEW ARTICLES than on the often brutalizing day-to-day activities of eighteenth- centuryjewish planters, but the competent original essays by Van der Meiden, Loker & Cohen, and Cohen do cover new historical ground. Most notable, perhaps, is a lengthy late eighteenth- century prayer written by a local cantor, presented here in both the original Hebrew and in English, which pleads for the Almighty's assistance against "our enemies, the cruel and rebelli- ous Blacks [maroons]," and prays that "terror and dread shall fall upon them." Finally, some recent largely-pictorial perspectives on the his- tory of Suriname. Two new editions of the stunning work of Maria Sibylla Merian bear witness to the continued interest in this pioneer naturalist, whose brief stay in Suriname ended in 1701. The Walburg Pers edition presents the complete Dutch version, reduced in page size from the original, with new English sum- maries facing each of the sixty plates, making a color version of the whole work available for the first time to a wide audience. De wisselende gedaante, in contrast, simply presents eleven of the plates with their original Dutch commentary, interspersed with bio- graphical information about Merian. One curiosity is that the Terra and Walburg Pers editions claim to have used the same Suriname Museum illustrations for reproduction, yet the Terra plates show lightly colored backgrounds and, in most cases, hand- written engraver's signatures, while the Walburg Pers plates — which seem garishly tinted and are printed on a white background — have the signatures dropped out and are all printed reversed. The interests of social scientists, as opposed to natural historians, in Merian's work derives largely from her several references to the uses of local plants by African slaves and Amerindians (e.g., the slaves' use of the seeds of Flos pavonis as an abortifacient) and from her fortuitous residence, during part of her Suriname stay, at the illfated Labadist retreat, Providence Plantation, whence a large number of rebel slaves escaped to become one of the founding clans of the Saramaka Maroons (see Price 1983). De Walburg Pers, with financial support from Suralco, has brought out yet another colored edition of Benoit's Surinam, originally published in French in 1839 and reprinted in a fine facsimile edition by S. Emmering in 1967 — this time in a Downloaded from Brill.com04/06/2021 01:09:21AM via free access REVIEW ARTICLES 9 7 reduced-page-size Dutch translation with an introduction by Chris Schriks and a fairly extensive English summary/com- mentary (originally published to accompany the Emmering fac- simile) by Silvia W. de Groot. This edition, the least expensive currently available, should serve to allow a wider audience, in- cluding many Surinamers, to enjoy for the first time this nineteenth-century classic. Albert Helman's richly illustrated adjosi to Suriname expresses a panoramic yet deeply poetic vision of his native land. From the opening pages of this oversized book, which overwhelm the reader with the geographical vastness and mystery of the rivers and forests of the Wild Coast, to its leisurely meanderings through colonial history, text and illustrations consistently complement each other and delight both eye and mind. In a work of this sort, occasional infelicities can be excused — the uncredited illustration on p. 141 in fact depicts a scène in Dominica, not Suriname; the plantation on p. 91 is Palmeneribo, not Palmenizibo; and so on. This is primarily a work of synthesis, a popular and accessible book that is at once a fine introduction for the general reader, and a provocative vision for the specialist to ponder. Taken together, this pepper-pot of fifteen books certainly con- stitutes a sufficiently "rare Soop," what one seventeenth-century observer (Cassidy and Le Page 1967, s.v. Pepper-pot) called "an excellent Breakfast for a Salamander, or a good preparative for a Mountebanks Agent, who Eats Fire one day, that he may get better Victuals the next." REFERENCES CASSIDY, F. G. & R. B. LE PAGE, 1967. Dictionary of Jamaican English. Cambridge: Cambridge University Press. HERDECK, DONALD E., et al., 1979. Caribbean wnters: a bw-biblwgraphical-critical encyclopedia. Washington, D.C.: Three Continents Press. HOLM, JOHN A. with ALISON W. SHILLING, 1982. Dictionary of Bahamian English. Cold Spring, N.Y.: Lexik House. MINTZ, SIDNEY W., 1982. Review of The Catalogue of the West India Reference Library. Revista Interamericana 12. Downloaded from Brill.com04/06/2021 01:09:21AM via free access 9 8 REVIEW ARTICLES PRICE, RICHARD, 1980. "So many different people in the same device": recent Caribbean bibliography. Nieuwe West-Indische Gids 54: 39—44. — 1982. Opodron: new pathways to Caribbean Knowledge. Nieuwe West-Indische Gids 56: 83-89. — 1983. First-Time: the historical visionqfan Afro-American people. Baltimore and London: Johns Hopkins University Press. S U E D B A D I L L O , J A L I L , 1977. Bibliografia antropológica para el estudio de los pueblos indigenas en el Caribe. Santo Domingo: Fundación Garcia Arévalo. RICHARD PRICE Department of Anthropology The Johns Hopkins University Baltimore MD 21218, U.S.A. Downloaded from Brill.com04/06/2021 01:09:21AM via free access work_acqttxb5ifebzn4remaruop5ae ---- Obituaries 272 Obituaries Drummond Hoyle Matthews, an Antarctic geologist who became one of the leaders in the understanding of plate tectonics, died in Taunton, Somerset, on 20 July 1997 at the age of 66. Matthews began research as a field geologist in the Falkland Islands Dependencies Survey (FIDS, now the British Antarctic Survey). He made the main contribution to the current geological understanding of the South Orkney Islands, but his Antarctic work was overshadowed by later accomplishments. In the weeks after his death, there were obituaries in The Independent (1 August), The Times (12 August), The Guardian (14 August), and Nature (7 August). Bob White, his former student and now professor of geophysics at the University of Cambridge, described him as one of the chief architects of the plate tectonics revolution. This accolade was earned for the recognition of patterns in magnetic anomalies and bathymetric features on either side of mid-ocean ridges and the sustained follow-up of those discoveries. In the five years from 1967 to 1972, the Cambridge marine geophysical group led by Matthews made 33 seagoing expeditions, and in the following dec- ade another 39 voyages were made to all oceans of the world. The esprit among that small group of scientists and technicians is reflected in Matthews' own memory of the time as the 'heroic' period of ocean exploration. Matthews was born on 5 February 1931 and grew up by the sea in Porlock, Somerset, an only child whose father died when he was young. He soon developed a passion for sailing. At Bryanston School, he did well and was greatly respected by staff. In September 1949, he became a midshipman in the Royal Navy, and he served in the Mediterranean Fleet before completing national service with the rank of Lieutenant. At King's College, Cambridge, he soon seemed des- tined for postgraduate studies, but in 1955 he graduated with only an average degree in geology and petrology. His mentor, Maurice Hill, still wanted him in the Department of Geology and Geophysics, but Matthews decided to try something else first. Cambridge had many Antarctic contacts, so it is hardly surprising that he was attracted to FIDS, although he committed himself to only one winter south. In 1955 a new hut had been built at Signy Island, and the following years were to be devoted to topographical and geological surveys of the South Orkney Islands. Only a week before sailing, Matthews learned that Derek Maling had already done two years of geology at Signy and Coronation islands. A last-minute attempt to meet failed, and Matthews did not benefit from Maling's experience until he had been in the South Orkneys a year and had almost completed his own fieldwork. Most fieldwork on Signy Island could be undertaken alone in days out from base. Coronation Island was a more serious undertaking, and throughout his time on the island Matthews was accompanied by the late Douglas Bridger (surveyor) and other members of Base H. Access to Coronation Island from Signy depended upon the state of the sea and/or ice. There were two dog teams at base, but 1956 was one of those rare winters when no fast ice formed between the islands. Two small clinker-built boats were in constant use as long as there was open water and in loose pack whenever it seemed feasible. Matthews was in his element, and his skill in handling boats rubbed off on everyone. He was adept at sculling over the stern with one oar 'fishwife fashion,' which was the ideal way of pushing a boat through brash. During the winter of 1956, the highlands of Coronation Island remained shrouded in orographic cloud for weeks at a time, making surveying impossible and glacier travel hazardous. During prolonged lie-ups, books became as important as rations. Short spells of good weather eventu- ally allowed the main objectives to be achieved. In the summer of 1955/56, a party was landed by ship at Meier Point to survey the west end of Coronation Island. The following summer another party led by Matthews was landed by ship at the eastern end of the island and worked from a base camp at Rayner Point. Towards the end of their time there, Matthews attempted to extend the geological survey eastwards by taking their one boat across the Lewthwaite Strait to Powell Island. This endeavour was thwarted by lack of a beach, so Matthews leapt onto the rocky coast for a few hours while Sandy Hall cruised about offshore. They landed briefly at Whale Skerries on the way back, then some days later returned to map these islets, camping on one of them. After RRS Shackleton had picked up the party from Rayner Point, Matthews and Hall landed briefly at two sites on Fredriksen Island and then had one last encounter with Coronation Island, an hour or so at Palmer Bay on one of the north coast promontories. Altogether Matthews had been on Coronation Island for 263 days. In the summer of 1957, Matthews returned to the FIDS Geology Group, recently set up under R.J. Adie at the University of Birmingham. The geology of the South Orkney Islands was to appear in three parts, each one published as a separate FIDS Scientific Report. Matthews and Maling submitted their contribution to 'Part I. Signy Island' in January 1959; it was eight years before it was published (Matthews and Maling 1967). By December 1959, Matthews had submitted 'Part II. Coronation Is- land,' but that significant work never appeared in his name (Matthews 1959b). He published two other papers: a technical note (Matthews 1958) and a review of the Scotia Arc incorporating marine interests that were to dominate OBITUARIES 273 the rest of his career (Matthews 1959a). Matthews received his PhD from Cambridge in 1961. He then served as a senior assistant in research in Cam- bridge's Department of Geodesy and Geophysics, where his investigations ofthe sea-floor helped him become one ofthe first scientists to understand plate tectonics. He later was promoted to assistant director of research (1966) and then to reader in marine geology (1971). With later colleagues, Matthews was apt to dismiss his early career with hints that those years were not all they might have been. Nevertheless, he was much moved by the Antarctic, and those who shared the experience re- member him as a friend with a subtle sense of fun, and as a reliable, thoughtful companion deeply committed to science, who always went the extra mile. W.LN. Tickell References Matthews, D.H. 1958. Dimensions of asymmetrical folds. Geological Magazine 95: 311-313. Matthews, D.H. 1959a. Aspects ofthe geology of the Scotia Arc. Geological Magazine 96: 425-441. Matthews, D.H. 1959b. The geology of the South Orkney Islands: II. Coronation Island. Unpublished paper. Cam- bridge: British Antarctic Survey Archives E53/GY14/6/ 1: 1-66. Matthews, D.H., and D.H. Maling. 1967. The geology of the South Orkney Islands: I. Signy Island. FIDS Scientific Reports 25: 1-32. Anne-Stine Ingstad, the Norwegian archaeologist, died at her home in Oslo on 6 November 1997, aged 79. By her excavations, she authenticated the first undoubted Norse ruins in North America, discovered by her husband Helge, scholar, sailor, and writer. Her husband, whom as Anne-Stine Moe she married in 1941, became interested in the Norse voyages after a visit to a Norse excavation in Greenland in the early 1950s. A study ofthe Icelandic sagas guided him on a long quest in the wake of Eric the Red and other Norse explorers. The climax of his quest came in 1960, when he sailed his ship from Greenland across to Labrador and southwards in search of Norse settlement sites. At L'Anse aux Meadows, his attention was drawn by a local man, George Decker, to some grassy mounds that Ingstad recognized as possible remnants of Scandinavian sod houses. The seven subse- quent summers of archaeological work directed by Anne- Stine were to prove his hunch correct. Anne-Stine enhanced the educational value of the project by using several local workers as part of her team, all of whom remember her with warm affection. During the excavations, the foundations of eight buildings were gradually uncovered, including a large house almost iden- tical to Leif Ericsson's 'great hall' in Greenland. An area used for smelting bog iron was also discovered, and artefacts such as a small stone spindle-whorl and a bronze tunic pin of Norse design were found. The Ingstads thought it more than probable that L'Anse aux Meadows was the place referred to in the sagas as 'Leifsbudir,' which had been the site of several winterings in Vinland. The radiocarbon (C14) method showed AD 1000+ 100 years as the date for the site, which accorded well with those indicated in the sagas. The Ingstads left further excavations to Parks Canada after 1968, but maintained a close interest in L'Anse aux Meadows, which, in 1980, to theirdelight, was declared by UNESCO an official World Heritage Site. Historical tourism at this site has since provided a valuable boost to the economy of a region hard hit by the ban on cod-fishing in Newfoundland's coastal waters, imposed by the Cana- dian government in 1992. After her work in Newfoundland, Anne-Stine Ingstad returned to the University of Oslo, where she had her book published in 1977: The discovery of a Norse settlement in America: excavations at L'Anse aux Meadows, 1961— 1968. In 1979, she received an honorary doctorate from Memorial University, St John's, Newfoundland. She and her husband set the seal on their work in Newfoundland with the publication by the Oslo University Press of The Norse discovery of America (1986) in two volumes. In 1991, the Royal Geographical Society honoured the Ingstads by awarding them jointly the Patron's Gold Medal. In their quiet and modest way, they took a wry pleasure in receiving it in the year before thequincentennial celebrations ofthe official discovery of North America by Christopher Columbus. Anne-Stine Ingstad is survived by her husband (now 98), their daughter Benedicta, and their grandchildren. Selma Barkham Geoffrey Hattersley-Smith work_anfzciqq3ndopdnovio4xldygq ---- EDITORIAL Meet the contributors Nicola Oberbeckmann-Winter Published online: 14 December 2011 # Springer-Verlag 2011 This opening issue of Analytical and Bioanalytical Chem- istry for 2012 celebrates the 10th anniversary of Analytical and Bioanalytical Chemistry and highlights current re- search by the Editors and members of the International Advisory Board. The strong commitment and dedication of the Editors and Advisory Board have been of enormous value in establishing ABC as an international journal of high rank and standing, publishing innovative research papers from all areas of analytical and bioanalytical science. In preparing this special issue, we are grateful for the overwhelming support we have received and thank the contributors for generously providing thirty-four research papers, nine critical reviews, and seven trend articles from the forefront of their research. Below, we invite you to meet the contributors to this exceptional 10th anniversary issue. Edgar A. Arriaga was Fesler–Lampert Chair in Aging Studies from 2007 to 2008 and is currently Professor of Chemistry at the College of Science and Engineer- ing, University of Minnesota, Minne- apolis, MN (USA). He is also a graduate of the Faculty of Biomedical Engineering, Gerontology, Molecular Biology, Biochemistry and Biophysics. He is a chartered member of the National Institutes of Health (NIH) Review Study Section Emerging Bio- technologies. His research program focuses on the development of bioana- lytical methods to investigate tissue complexity, single cells, and subcellular compartments. Applications of these methods include determination of the subcellular fate and metabolism of xenobiotics, and investigating subcellular processes associated with the causes of aging. Marco Aurélio Zezzi Arruda is Full Professor at the University of Campinas—Unicamp, Department of Analytical Chemistry, also belonging to the National Institute of Science and Technology—INCT—for Bioanalysis. The main lines of research of his group includes mass (ICP–MS, LA–ICP–MS, MALDI-QTOF-MS, ESI-MS, TWIMS) and atomic spectrometry (FAAS, TS- FF–AAS, ETAAS, ICP–OES), sample preparation, mechanization, and bioanal- ysis with emphasis on proteomics and metallomics. He is the author or co- author over 130 research articles and five books, and is on the Editorial Staff or Advisory Board of four journals. His current research interests include trans-disciplinary work involving the comparative omics of plants (i.e. soybean, sunflower) and human body fluids (i.e. blood serum) to identify possible biomarkers for transgenic species and human diseases, and to evaluate reactive oxygen species production, and (metallo)proteins responses under stress in a given system. N. Oberbeckmann-Winter (*) Analytical and Bioanalytical Chemistry, Springer, Tiergartenstrasse 17, 69121 Heidelberg, Germany e-mail: abc@springer.com Anal Bioanal Chem (2012) 402:15–23 DOI 10.1007/s00216-011-5537-7 Antje J. Baeumner is Professor of Biological Engineering and Director of Graduate Studies in the Department of Biological and Environ- mental Engineering at Cornell Univer- sity in Ithaca, NY, USA. She is on the Board of Directors of the Society of Electroanalytical Chemistry, a member of the Extended Executive Committee of the International Association of Environmental Analytical Chemistry, was the 2010 Chair of the Gordon Research Conference on Bioanalytical Sensors, and has received numerous honors in recent years including being Finalist for the Blavatnik Award of the NY Academy of Sciences, and recipient of a Humboldt Research Fellowship and a German National Science Foundation Mercator Guest Professorship. Her research is focused on the development of micro-total analysis systems and smart lateral flow assays for detection of pathogens and toxins in food and the environment, and for medical diagnostics. Francesco Baldini graduated in physics from the Uni- versity of Florence in 1986. He is Senior Scientist at the Institute of Applied Physics of the National Research Council and his main re- search activity is devoted to the development of optical sensors/sys- tems for chemical and biochemical analysis. He is author of more than one hundred publications on the subject in international journals, in scientific books, and in international conference proceedings. In 2009 he was appointed as a fellow of SPIEC society for his “achievements in biological and chemical sensing in biomedicine”. Damià Barceló Cullerés is Full Research Professor and Deputy Director at IDAEA-CSIC and, since 2008, Director of the Catalan Institute for Water Research (ICRA). From 2009 he has been Visiting Professor at King Saud University, Riyadh, Saudi Arabia. In 2007 he received the King Jaime I Award from the Generalitat of Valen- cia (Spain) on the Protection of Nature. His research interests are in environmental analysis, and the fate and behavior of organic pollutants in water, sediment, and biota, using mass spectrometric techniques, immunoassay, toxic assays and biosensors. During recent years his interests have also included bridging environment and health risks in the field of emerging contaminants. Boguslaw Buszewski is Head of the Chair of Environ- mental Chemistry and Bioanalysis at the Faculty of Chemistry, Nicolaus Copernicus University. He serves as President of the Polish Chemical Society, Vice Chair of the Commit- tee of Analytical Chemistry of the Polish Academy of Sciences, and is a member of the Advisory Board of the Austrian Academy of Sciences. Dr Buszewski is president of the European Society for Separation Sci- ence (EuSSS). His main scientific interests cover environmental analy- sis, chromatography, and related techniques (HPLC, SPE, GC, CZE, adsorption, sample preparation), spectroscopy, utilization of waste and sludge, and chemometrics. He is also the chairman of the Central European Group for Separation Sciences (CEGSS), the chairman of the Societas Humboldtiana Polonorum, and member of the Steering Committee of the Division of Environmental Chemistry of the European Association for Chemical and Molecular Sciences (EuCheMS). Rafael Cela Torrijos is Professor of Analytical Chemistry at the University of Santiago de Compos- tela, Spain, and the Head of the Labora- tory for Analytical Chemistry in the Research Institute of Food Analysis at the same university. Previously, he was at the Universities of Madrid (Complu- tense) and Cadiz, belonging to the group of analytical chemists that started the development of chemometrics in the 1980s in Spain. His research has focused on the analytical applications of separa- tion science, and, particularly, the devel- opment and optimization of sample preparation techniques in chromatographic analysis, including experimental designs and the development of computer-assisted chromatographic methods. He is the author or coauthor of more than 200 scientific papers and several textbooks. Craig A. Aspinwall is an Associate Professor in the Depart- ment of Chemistry and Biochemistry at the University of Arizona, where he has been since 2002. His research focuses on the development and application of opti- cal and electrophysiological sensors and microscale separations for the analysis of biological systems. He is a recipient of the ACS Division of Analytical Chemis- try Award for Young Investigators in Separation Science (2009) and was an inaugural ACS GREET (Global Re- search Experiences, Exchanges, and Training) Scholar (2011). 16 N. Oberbeckmann-Winter Sapna Deo is Associate Professor in the Department of Biochemistry and Molecular Biology at the University of Miami, Miller School of Medicine. Dr Deo’s research interest is in the development of novel nanobioana- lytical techniques based on luminescence and quantum dots for detection of micro- RNAs and RNA molecules for applica- tion in biomedicine, diagnosis, and pathogen detection. Other areas of re- search include development of molecular probes for biosensing and bioimaging applications. Her research also focuses on creating luminescent nanocarriers for targeted imaging and sensing applications in biomedicine. She is a author and co- author of over 70 scientific publications and several patents and a recipient of the NSF-CAREER Award. Erkang Wang was Director of the Changchun Institute of Applied Chemistry. During his active career he acted as visiting professor in the US, France, Japan, and Hong Kong, and has presented over 150 seminars and keynote lectures in 26 countries. He has published more than 900 papers and monographs in international journals. He is member of various prestigious chemi- cal societies, among others the Japan Society for Analytical Chemistry, the Academy of Sciences for the Developing World, and the Chinese Academy of Sciences. Erkang Wang holds more than ten awards from Chinese national and provincial governments and two international awards. His research interest is focused on analytical chemistry, electrochemistry, electroanalytical chemistry, bioelectrochemistry, and environmental chemistry. Jörg Feldmann has held the Chair in Environmental Analytical Chemistry and been Director of TESLA (Trace Element Speciation Laboratory) at the University of Aberdeen (Scotland, UK) for 14 years. He received his PhD from the University of Essen (Germany) and was Feodor Lynen Fellow (Alexander von Humboldt Foundation) for two years at the Univer- sity of British Columbia (Canada). He has pioneered the simultaneous hyphen- ation of ICPMS and ESI-MS to HPLC for determination of labile metal biomol- ecule interactions which are crucial to explaining environmental and biological processes. In addition he uses laser ablation ICPMS extensively for bioimaging of elements. He is author or coauthor of more than 150 peer-reviewed publications. John Fetzer is author or coauthor of over 130 research articles, reviews, and book chapters. He worked for over 20 years as an analytical chemist for the Chev- ron Corporation and now runs his own consulting company, Fetzpahs Consult- ing, in Hercules, CA, USA. He is author of the book Career management for chemists-a guide to success in a chemistry career. Philippe Garrigues is a CNRS Research Director and Head of the Department of Molecular Scien- ces (CRCM, FR 1981 CNRS) at the University of Bordeaux 1, France, with around 200 researchers involved in a variety of chemistry disciplines (theo- ry, analysis, environment, spectrosco- py, synthesis). Dr Garrigues’s personal research interests are analytical aspects (chromatography and spectroscopy) of the detection of organic pollutants and their environmental fate and toxicolog- ical effects. Recently, he has been involved in the development of bio- chemical markers as early warning systems for the toxicological evaluation of ecosystems by coordination of large research projects (i.e. BIOMAR, BEEP) supported by DG Research (European Commission, Brussels). Sylvia Daunert holds the Lucille P. Markey Chair of Biochemistry and Molecular Biology at the Miller School of Medicine of the University of Miami. Previously, she was the Gill Eminent Professor of Chemistry at the University of Ken- tucky where she had a secondary appointment in the pharmaceutical sciences. She is a Fulbright Scholar and recipient of numerous awards, for example the A.F. Findeis Award of the American Chemical Society and the special Creativity Award from the National Science Foundation. Dr Daunert’s research interests are in bionanotechnology at the interface between analytical biochemistry, molecular biology, and bioengineering. Her group uses recombinant DNA technology to design new molecular diagnostic tools and biosensors, with biomedical, environmental, and pharmaceutical applications, based on genetically engineered proteins and cells. The research also focuses on the design of sensing arrays for detection of molecules in small volumes, by use of microfluidics, and in the development of biomaterials for responsive drug- delivery systems. Meet the contributors 17 Walter Giger is Scientist Emeritus at Eawag, the Swiss Federal Institute of Aquatic Science and Technology, and Professor Emeritus at ETH, the Swiss Federal Institute of Technology. He is active as an Independent Consultant for Giger Research Consulting in Zurich and as Adjunct Professor at the Curtin Water Quality Research Centre, Curtin Uni- versity of Technology, Perth, Australia. He is an expert on organic contami- nants in the aquatic environment and in the evaluation of chemical, physical and biological processes determining the environmental fate of chemicals. Since 2009, Dr Giger has chaired the Division of Chemistry and the Environment of the European Association of Chemistry and the Environment of the European Association of Chemical and Molecular Sciences (EuCheMS). Heidi Goenaga-Infante is Principal Scientist at LGC, UK. Her research interests lie in trace element speciation analysis, metallomics research, combined use of elemental and molecular mass spectrometry, size-based element fractionation and the development of reference methods for characterization of “speciated” reference materials and stand- ards. Dr Goenaga-Infante is the UK representative at the Inorganic Analysis Working Group of the CCQM, the inter- national Consultative Committee for Me- trology in Chemistry. Klaus Gustav Heumann is Emeritus Professor of Analytical Chemistry at the Johannes Gutenberg University Mainz. His research inter- ests lie in the development and appli- cation of analytical methods for the determination of trace elements and trace amounts of elemental species, using inductively coupled plasma mass spectrometry, thermal ionization mass spectrometry, different types of optical atomic spectrometry, and elec- troanalysis as detection methods, and high-performance liquid chromatogra- phy, capillary electrophoresis, and capillary gas chromatography as separation methods. He has received several awards, including the Clemens Winkler Medal of the German Society for Analytical Chemistry in 2004 for his scientific lifework and for continuous support of analytical chemistry in Germany. In 2007 he received the European Award for Plasma Spectrochemistry. He is a member of several national and international scientific societies and he was a member of the IUPAC Commission on Atomic Weights and Isotopic Abundances for 12 years and chairman from 1991 to 1995. Jiří Homola is Head of the Photonics Division and Chairman of the Department of Optical Sensors at the Institute of Photonics and Electronics, Prague (Czech Republic). He also is Affiliate Professor at the University of Washington, Seattle (USA) and Associate Professor at Charles University in Prague (Czech Republic). His research interests are in photonics and biophotonics, in particular in optical sensors and biosensors. J. Homola is a recipient of the Roche Diagnostics Prize for Sensor Technology and Premium Academiae. Maciej Jarosz is Chair of Analytical Chemistry at the Faculty of Chemistry, Warsaw Universi- ty of Technology, Poland, Vice-President and treasurer of the Board of the Polish Chemical Society, member of the Board of the Committee on Analytical Chemis- try, Polish Academy of Sciences, Nation- al Representative in the Division of Analytical Chemistry of IUPAC, and member of the Steering Committee of the Division of Analytical Chemistry of EuCheMS. He is author or co-author of 83 original papers and chapters in mono- graphs. His scientific interests focus on cultural heritage preservation (identification of natural products in art works); food and pharmaceutical analysis, and environmental speciation analysis. He was awarded (among others) the Honored Award of the Polish Chemical Society and the Professor Andrzej Waksmundzki Medal—Committee on Analytical Chemistry, Polish Academy of Sciences Award. Günter Gauglitz is Professor at the Eberhard-Karls- University of Tübingen working in analytical and physical chemistry. He was chairman of the GDCh Division of Analytical Chemistry and chaired the Europt(r)ode VIII meeting. He is also member of the DAC in EuCheMS. For the last 10 years his main scientific interests have centered on research on and development of chemical and biochemical sensors with special focus on characterization of the interfaces of polymers and biomembrane surfaces, spectroscopic techniques, use of spectral interferometry to monitor changes in optical thickness of thin layers, and the effects of Fresnel reflectivity at interfaces. 18 N. Oberbeckmann-Winter Uwe Karst has been Full Professor of Analytical Chemistry at the University of Münster since 2005, and was previously Full Professor of Chemical Analysis at the University of Twente, The Nether- lands, from 2001–2005. His current research interests cover hyphenated techniques, speciation analysis, minia- turization, and derivatization. In 2009, he received the Fresenius Prize of the German Chemical Society (GDCh). Takehiko Kitamori is Full Professor at the Department of Applied Chemistry, Graduate School of Engineering, University of Tokyo, and also Dean of the Faculty of Engineering and the Graduate School of Engineering. His research activity covers analytical chemistry, applied laser spectroscopy, and micro and extended nanochemistry. He has re- ceived several prestigious awards, in- cluding the Chemical Society of Japan Award for Creative Work (2006) and the IBM Faculty Award (2008). Rudolf Krska is Full Professor of (Bio)Analysis and Organic Trace Analysis at the University of Natural Resources and Life Sciences, Vienna (BOKU) and Head of the De- partment of Agrobiotechnology (IFA- Tulln) at BOKU. Rudolf Krska, who is also Head of the Center for Analytical Chemistry at the IFA-Tulln, is an expert in food and feed analysis by chromato- graphic, mass spectrometric, and immu- noanalytical techniques. He has established intensive interdisciplinary cooperation with universities and com- panies and has been coordinator and work package leader of several European Commission-funded projects dealing with the determination of mycotoxins and allergens in food. As member of JECFA (Joint Expert Committee for Food Additives) of the FAO/WHO he has evaluated the affect of trichothecenes on humans. Dr Krska is also involved in other international activity, for example two working groups of the European Committee for Standardization. Bernhard Kuster is a chemist by training and obtained his PhD in Biochemistry at the Univer- sity of Oxford, UK. After post-doctoral terms at the EMBL in Heidelberg and Odense University, Denmark, he worked in the biotechnology firm Cellzome for seven years where he held a number of senior research positions. Professor Kuster currently holds the Chair for Proteomics and Bioanalysis at the Technische Univer- sität München and is also head of the department for Biosciences at the TUM. His research interests include chemical biology, cancer drug discovery, and development of technology for proteomics and mass spectrometry. Professor Kuster has published more than 60 papers which have collected over 8,000 citations and he has won awards from the German Society for Mass Spectrometry, the German Academic Exchange Service, and the European Molecular Biology Organisation. Olivier Laprévote is currently Professor of Toxicology at the University Paris Descartes (Faculty of Pharmacy) and at Lar- iboisière Hospital in Paris. He was Group Leader of the Mass Spec- trometry Laboratory of the Institute for Natural Compounds Chemistry at Gif-sur-Yvette (France) until 2008. His scientific interests are in the development of original mass spectrometric methods for character- ization of natural molecules in com- plex biological matrices. Among his past research activity, mass spec- trometry imaging was prominent, with a particular interest in biomedical applications. Kiyokatsu Jinno is currently trustee and Vice-President of Toyohashi University of Technolo- gy, Toyohashi, Japan. His major re- search interests are in molecular recognition in chromatography, reten- tion mechanisms in liquid chromatog- raphy, design of novel stationary phases, miniaturized sample prepara- tion processes with newly designed materials, and their combination for liquid phase separations, development of capillary separation techniques, hy- phenated techniques in chromatogra- phy, and spectroscopy and computer networking in the separation sciences. He has received several awards for his contributions to chromatography and related analytical techniques: the Tokai Chemical Industry Award in 1986, the Russian Tswett Medal in 1996, the University of Helsinki Medal in 1998, the Golay Award in 1999, the Society Award from the Japanese Society for Chromato- graphic Sciences in 2000, and the Society Award from the Japan Society for Analytical Chemistry in 2003. Meet the contributors 19 Frances S. Ligler is the Navy’s Senior Scientist for biosensors and biomaterials and a member and past chair of the Bioengi- neering Section of the US National Academy of Engineering. She has over 350 full-length publications and patents (>7,000 citations), which have led to eleven commercial biosensor products and won her the Homeland Security Award (Biological, Radiological, Nu- clear Field) of the Christopher Colum- bus Foundation and the Presidential Rank of Distinguished Senior Profes- sional awarded by President Bush. Wolfgang Lindner is expert in separation sciences with focus on life-science analysis and material sci- ence, developing diverse stationary phases with dedicated selectivity properties. Among these the chiral stationary phases became the most widely known. Since 1996 Wolfgang Lindner has held the Chair of Analytical Chemistry at the University of Vienna, Austria. He is author and co- author of more than 400 publications. Among other prizes, he has received the Chirality Medal, the A.J.P. Martin Gold Medal, the Halasz Medal, and, very recent- ly, the ACS Award for Chromatography. R. Kenneth (Ken) Marcus is Professor of Analytical Chemistry at Clemson University. Professor Marcus’ research program covers three distinct lines of study: the use of capillary- channeled polymer (C-CP) fibers and films for protein separations; the use of particle beam LC–MS for profiling botanical products (nutraceuticals); and the development of liquid sam- pling-atmospheric pressure glow dis- charge (LS-APGD) microplasmas for spectrochemical analysis. In 2010 he was honored by election to Fellowship of the Royal Society of Chemistry. Hans H. Maurer is Head of the Department of Experi- mental and Clinical Toxicology of the Saarland University in Homburg (Saar). He has published over 200 original papers and 30 invited reviews on his main two areas of research, analytical toxicology (GC– MS, LC–MS) and metabolism of xenobiotics. He has received several international scientific awards, and in 2007 he was awarded the title of Doctor Honoris Causa by the Uni- versity of Ghent, Belgium. Juris Meija is a Research Officer at the Institute for National Measurement Standards, National Research Council, Canada. His research interests encompass the- oretical analytical chemistry, isotope - ratio measurements, and the history of chemistry. He serves as Column Editor for the Analytical Challenge series in Analytical and Bioanalytical Chemis- try and is the Secretary of the IUPAC Commission on Isotopic Abundances and Atomic Weights. Cynthia Larive is Professor of Analytical Chemistry at the University of California, Riverside. Dr Larive’s research in bioanalytical chemistry focuses on the structural char- acterization of carbohydrates and plant- based metabolomics. She has an active research program involving bioanalytical and environmental analytical applica- tions of NMR spectroscopy. Professor Larive is also active in curricular reform and promotion of undergraduate re- search. She is editor-in-chief and princi- pal investigator of the Analytical Sciences Digital Library (http://www. asdlib.org), an Internet-based resource for instructors, students, and practitioners of analytical chemistry. This digital library is a collection of peer-reviewed web sites on topics including pedagogical approaches, analytical techniques, applica- tions, and classroom resources. 20 N. Oberbeckmann-Winter http://www.asdlib.org http://dx.doi.org/ David S. Moore is Research Scientist and Team Leader in the Shock and Detonation Physics Group at Los Alamos National Labo- ratory. Moore received the 2009 Los Alamos Fellows Prize for Leadership in Science and Engineering, and was an Alexander von Humboldt Fellow and a Los Alamos National Laboratory Director’s Postdoctoral Fellow. His research team exploits ultrafast lasers to measure, in real time, chemistry and phase transitions in shock compressed materials, as well as for development of optimum coherent control methods for condensed phase chemistry (initiation of explosives) and the dynamic detection of explosives, especially at standoff distances. David C. Muddiman is currently Professor of Chemistry and Founder and Director of the W.M. Keck FT–ICR Mass Spectrometry Laboratory at North Carolina State University in Raleigh, NC, USA. His research interests include the development and application of advanced separations and mass spec- trometry. His group has presented over 350 invited lectures and presentations at national and international meetings, has published over 175 peer-reviewed papers and reviews, and has been awarded three US patents. He is the recipient of the 2010 Biemann Medal, American Society for Mass Spectrometry, 2009 NCSU Alumni Outstanding Research Award, the 2004 ACS Arthur F. Findeis Award, the 1999 American Society for Mass Spectrometry Research Award, and the Safford Award, University of Pittsburgh, for Excellence in Teaching. Reinhard Nießner is Full Professor of Analytical Chem- istry at the Technical University of Munich. His research interests are in environmental analytical chemistry, es- pecially devoted to applications of laser spectroscopy, nanoparticle char- acterization, and microarray technolo- gy. His main areas of interest are aerosols, hydrocolloids, and biofilms, in the water and atmosphere. He has received several international awards, e.g. the Emanuel–Merck Prize for Analytical Chemistry (1990), the Smo- luchowski Award for Aerosol Research of the Association for Aerosol Research (1991), the Fritz–Pregl Medal of the Austrian Society for Analytical Chemistry (1996), and the Fresenius Award for Analytical Chemistry of the German Chemical Society (2000). Professor Nießner has served in many national and international scientific organizations, e.g. within IUPAC as a Titular Member and the European Science Foundation. Giuseppe Palleschi is Full Professor of Analytical Chem- istry and was Head of the Department of Chemical Science and Technology of the University of Rome “Tor Ver- gata” between 1995 and 2007 In the 2000 he obtained the “Laurea Honoris Causa” from the University of Bucharest for his activity in the field of chemical sensors for food and environmental control. Professor Palle- schi’s research over the last 30 years has been focused on the development of chemical sensors and bio and immunosensors for use in biomedicine, food and environmental analysis. He is the author of more than 200 papers in international scientific journals and invited speaker at many International Congresses. He has been visiting scientist for two years in the USA (University of New Orleans), for three months in the UK (University of Cranfield), and one month at RCAST (Japan). Aldo Roda is Professor of Analytical Chemistry at the Alma Mater Studiorum University of Bologna, Italy. He is Vice-President of the Italian Society of Chemistry (“Società Chimica Italiana”, SCI) and a member of the Academy of Science, Institute of Bologna. His main research interests center on the development of devices, cellular biosensors, and ultra- sensitive analytical methods and imag- ing based on chemi-bioluminescence applied to clinical chemistry, medicinal chemistry, environmental chemistry, cultural heritage, and food analysis. He is co-author of more than 400 articles published in international journals, and 24 international patents on new bile acids, antioxidant drugs, new luminescent labels, biosensors, and luciferase probes. Boris Mizaikoff is currently Chaired Professor and Director of the Institute of Analytical and Bioanalytical Chemistry at the University of Ulm, Germany. He is also a member of the Center for Cell and Molecular Signaling at Emory University, Atlanta, GA, USA. His research interests focus on optical sensors, biosensors, and biomimetic sensors operating in the mid-infrared spectral range, quantum cascade lasers, system miniaturization and integration based on micro and nanofabrication, multifunctional (nano)analytical tech- nology, focused ion-beam techniques, development of chemical recognition layers for separation and sensing applications, environmental and process analysis, and biomedical diagnostics. Meet the contributors 21 Reiner Salzer retired as Professor of Analytical Chemistry at the Technische Universität Dresden, Germany, in 2007. His main scientific interests include molecular monitoring for early diagnosis of diseases, integration of biologically active functions into polymers, and electronic media in university educa- tion. Professor Salzer has authored 14 patents in different fields of analytical chemistry, and over 250 books and scien- tific publications. Professor Salzer has been elected on to a variety of national and international boards. He is a member of the Norwegian Academy of Science, a recipi- ent of the Emich Plaque of the Austrian Society of Analytical Chemistry (2007) and of the Clemens Winkler Medal of the Division Analytical Chemistry of the German Chemical Society (2011). He served as President of the Division Analytical Chemistry of the German Chemical Society, and is National Delegate to the Division of Analytical Chemistry of EuCheMS, where he is Head of the Study Group Education. He is Vice- Chairman of the ECTNA Label Committee for the Chemistry Eurobachelor and Chemistry Euromaster and is currently involved in the development of a quality scheme for a Eurodoctorate label. Alfredo Sanz-Medel has been Professor in the Department of Physical and Analytical Chemistry of Oviedo University (Spain) since 1982. He is author or co-author of approximate- ly 500 scientific publications in interna- tional journals, several patents, and books. His current research interests include new atomic detectors and ion sources for ultra- trace analysis using plasmas, new molec- ular optical sensors, particularly those based on the use of quantum dots, and hybrid techniques, coupling a separation unit and an atomic detector for ultra-trace and trace metal speciation to solve bio- logical and environmental problems, and speciation for proteomics. The objective of this work is to integrate mass spectrometry (MS), “molecular” (matrix-assisted laser desorption/ionization and electrospray MS), and “atomic” (inductively coupled plasma (ICP)MS) techniques, and introduction of the extensive use of ICP–MS to carry out “heteroatom-tagged proteomics”, for both qualitative and quantitative purposes. At Euroanalysis 2007, in Antwerp, he received the Robert Kellner Award. In 2011 he was granted the European Award of Plasma Spectrochemistry. Frieder W. Scheller is Visiting Professor at University of Potsdam and consultant at the Fraunhofer IBMT. For many years he headed the Department of Bioelectrochemistry/Bio- sensors at the Central Institute of Molec- ular biology of the German Academy of Sciences, Berlin-Buch. In 2001 he was President of the German Society of Biochemistry and Molecular Biology. He has been working on the development of biosensors for more than 30 years. At present his research interest is focused on bioelectrocatalysis and molecularly imprinted polymers. André M. Striegel is a Research Chemist at the National Institute of Standards and Technology (NIST). He was previously Assistant Professor of Analytical and Materials Chemistry at Florida State University (FSU) and, before that, Research Spe- cialist at Solutia Inc. He was the inaugural recipient of the ACS-DAC Award for Young Investigators in Sep- aration Science and inaugural Professor in Residence for Preservation Research and Testing at the US Library of Congress. He is also the recipient of an Eli Lilly Analytical Chemistry Grantee Award, an FSU First Year Assistant Professor Award, and a Solutia Technical Achievement Award. His main research interests are in separation science of macromolecules. Ralph Sturgeon is Principal Research Officer in the Chemical Metrology Group of the Institute for National Measurement Standards, National Research Council, Canada. His interests lie in inorganic analytical chemistry, including trace element analysis, vapor generation, organometallic speciation, and produc- tion of certified reference materials with a focus on atomic and mass spectrometric detection. Jorge Ruiz Encinar has been Associate Professor at the University of Oviedo (Spain) since 2010. His research interests are mass spectrometry and stable isotope-based methods, mostly applied to environ- mental science, speciation, and heteroatom-tagged proteomics, and the development of new biological appli- cations of functionalized nanoparticles. In 2007 he was awarded the “Young Chemist Prize” by the Spanish Royal Society of Chemistry. He is currently the coordinator of the International Master in Analytical and Bioanalytical Sciences at the University of Oviedo (dual diploma with the University of Pau, France). 22 N. Oberbeckmann-Winter Miguel Valcárcel Cases has been Full Professor of Analytical Chemistry at the University of Córdoba since 1976. He is author and co-author of 800 scientific articles, seven mono- graphs, eight textbooks, and sixteen chapters of books. He has been the coordinator of 25 Spanish scientific research projects and 14 of internation- al nature, and of 12 contracts with private firms, and has promoted a spin- off devoted to nanotechnology. Profes- sor Valcárcel has been co-supervisor of 68 doctoral theses and invited lecturer at 70 international meetings. He is the recipient of scientific national (e.g. Award in Chemistry in Spain, 2006) and international (e.g. Robert Boyle Medal of the RSC, 2004) prizes as well as Doctor Honoris Causa by the University of Valencia (Spain). Frank Vanhaecke is Professor of Analytical Chemistry at Ghent University (Belgium) where he leads the “Atomic and Mass Spec- trometry—A&MS” research group. Prof Vanhaecke has a passion for the determination, speciation, and isotopic analysis of (trace) elements by ICP– mass spectrometry (ICP–MS). He is an author of approximately 170 papers in peer-reviewed international journals and several book chapters. In 2011, he received a “European Award for Plasma Spectrochemistry”. Weihong Tan obtained his PhD in Physical Chemis- try in 1993 at the University of Michigan and is currently V.T. and Louis Jackson Professor of Chemistry. His research interests are in molecular engineering, bioanalysis, bionanotech- nology, and chemical biology. His group has engineered nucleic acid probes for biosensing and DNA nano- motors. The Tan group has also devel- oped numerous bioconjugated nanostructures, for example silica nano- particles, for molecular imaging, cell separation, and sensitive analytical de- tection. With the development of cell-based SELEX, they have generated a variety of aptamers for cancer cells as molecular tools for early cancer detection, targeted treatment, and biomarker discovery. Stephen A. Wise is Head of the Analytical Chemistry Division at the National Institute of Standards and Technology (NIST). Dr Wise’s research efforts focus on the development of certified reference materials for trace organic constituents in environmental, clinical, food, and dietary supplement matrices; develop- ment of chromatographic methods for organic analysis; and investigations of chromatographic separation mecha- nisms and chromatographic selectivity. He has served as Chairman of the Division of Analytical Chemistry of the American Chemical Society (1996) and as President of the International Society of Polycyclic Aromatic Compounds (2003–2005). He received the 2001 Polycyclic Aromatic Hydrocarbon Research Award presented by the International Society of Polycyclic Aromatic Compounds (ISPAC) and the 2006 Harvey W. Wiley Award from AOAC International. Xinrong Zhang received his Bachelor’s and Master’s degrees in chemistry from Shaanxi Normal University, China, and Ph.D. degree in analytical chemistry from University of Ghent, Belgium. He was appointed Professor of the Depart- ment of Chemistry, Tsinghua Universi- ty, China, in 1997. His current research interests are focused on developing optical and mass spectrometric techni- ques for biomedical and environmental analysis. He published over 170 papers and several book chapters (in English) on these topics. Toyohide Takeuchi is Professor of Chemistry at the Faculty of Engineering, Gifu University, Japan. He received a Bachelor’s degree in engineering (1977), a Master’s degree in engineering (1979), and a Doctorate in engineering (1985) from Nagoya University. He was appointed Research Associate (1980) and Associate Profes- sor (1989) at Nagoya University, and joined Gifu University as Associate Professor in 1992, where he was promoted to Professor of Chemistry in 2001. During 1985 and 1986 he was appointed postdoctoral fellow at Ames Laboratory in USA. His research interests include the development of capillary columns, and novel detection and separation systems for capillary LC. He is author or co-author of approximately 240 original papers. He received the Japan Society for Analytical Chemistry Award for Young Scientists in 1987, the Takeda Techno-Entrepreneurship Award in 2001, and The Society for Chromatographic Sciences Award in 2004. Meet the contributors 23 Meet the contributors work_ap3p6d42rvh3td4aydbhpxpenm ---- 107 Invited Review: Cocoa and chocolate consumption 2008;21(3)S Afr J Clin Nutr Afoakwa EO, MPhil, PhD Centre for Food Quality, Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, United Kingdom Department of Nutrition and Food Science, University of Ghana, Legon – Accra, Ghana. Nestlé Product Technology Centre York, York, United Kingdom Correspondence to: E Afoakwa, e-mail: e_afoakwa@yahoo.com Keywords: cocoa; chocolate; aphrodisiac; flavanols; polyphenols; cardioprotection Cocoa and chocolate consumption – Are there aphrodisiac and other benefits for human health? Introduction “Cocoa” is a corrupted word for cacao, which is taken directly from the Mayan and Aztec languages. Chocolate is derived from cocoa beans, central to the fruit of the tree Theobroma cacao (Figure 1). Theobroma (from the Greek for “food of the gods”) are of the family Sterculiaceae. They comprise two principal types: Criollo, constituting about 5% of the world’s cocoa production, and the more common Forastero, which has smaller, flatter, purple beans. A third variety, Trinitario (a more disease-resistant hybrid of Criollo and Forastero), is regarded as a flavour bean.1 Theobroma cacao grows between the tropics of Cancer and Capricorn, with varieties originating in the forest areas of South America. Forastero – basic cocoa – grows mainly in Brazil and West Africa, while the flavour cocoas (largely hybrids), thrive in Central and South America. The Aztecs in Mexico cultivated cocoa from South America via the Caribbean Islands and Hernandos Cortés, a Spanish took cocoa to Spain as a beverage and to Spanish Guinea as a crop. West Africa currently produces more than 70% of the world’s cocoa, with production dominated by the Ivory Coast (39%), Ghana (21%), Nigeria (6%) and Cameroon (5%).2 The use of cocoa beans dates back at least 1 500 years, when the Aztecs and Incas used the beans as currency for trading or to produce so-called chocolatl, a drink made by roasting and grinding cocoa nibs, mashing them with water and often adding other ingredients such as vanilla, spices and honey.3 In the 1520s, the drink was introduced to Spain4, although Coe and Coe5 emphasise that the European arrivals in the New World, including Christopher Columbus and Herman Cortes, were unimpressed with the Mayan beverage and therefore sweetened it with honey. The conquistadors nevertheless familiarised the chocolate beverage throughout Europe but, being expensive, it was initially reserved for consumption by the highest social classes. It was only in the 17th century that the consumption of chocolate spread through Europe. In 1847, Joseph Fry was the first to produce a plain eating chocolate bar in the United Kingdom, made possible by the introduction of cocoa butter as an ingredient.4 Demand for cocoa then sharply increased and chocolate processing became mechanised with the development of cocoa presses for the production of cocoa butter and cocoa powder by Conrad J van Houten in 1828, milk chocolate by Daniel Peters in 1876 after Henri Nestlé’s invention a decade earlier, and the conche process by Rodolphe Lindt in 1880.3 Chocolate confectionery is now ubiquitous, with consumption averaging 8,0 kg per person per annum in many European countries.6 Cocoa and chocolate products have recently attracted the attention of many investigators and the general consuming public because of their potential nutritional, medicinal and mystical properties. Chocolate is a very complex food and scientists continue to investigate it in order to unlock its potential benefits and secrets. When consumed, for example, it has been observed to have effects on human behaviour and health. Over the past decade, several studies have also reported that its consumption can contribute to the attainment of optimal health and development as well as play an important role in reducing the risk or delaying the development of chronic disease, such as cardiovascular disease (CVD), cancer and other age-related disease.7,8,9 Abstract Cocoa and chocolate have been acclaimed for several years for their possible medicinal and health benefits. It is only recently, however, that some of these claims have been more clearly identified and studied. Recent epidemiological and clinical studies, for example, have shown that dietary supplementation with flavonoid-rich cocoa and chocolate may exert a protective effect on low-density lipoprotein (LDL) oxidation, which has been associated with a reduced risk of developing atherosclerosis. Some of the identified benefits of flavonoid-rich cocoa and chocolate include antioxidant properties, reduced blood pressure via the induction of nitric-oxide (NO)-dependent vasodilation in men, improved endothelial function, increased insulin sensitivity, decreased platelet activation and function, as well as modulated immune function and inflammation. Furthermore, chocolate has been reported to release phenylethylamine and serotonin into the human system, producing some aphrodisiac and mood-lifting effects. Since these claims could have implications for the consumption levels of cocoa and chocolate products on the global market, understanding the critical factors involved and their potential benefits are currently thought to be of great importance to consumers. S Afr J Clin Nutr 2008;21(3):107-113 Invited Review: Cocoa and chocolate consumption 108 Invited Review: Cocoa and chocolate consumption 2008;21(3)S Afr J Clin Nutr Recently, chocolate has gained a reputation as an aphrodisiac, as is the case with lobster, crab legs, pine nuts, walnuts, alcohol and Viagra. In most parts of the world, chocolate is also associated with romance – and not without good reason, as it was viewed as an aphrodisiac by the Mayan and Aztec cultures, which believed that it invigorated men and made women less inhibited.10 The reputed aphrodisiac qualities of chocolate are, however, most often associated with the simple sensual pleasure of its consumption. Additionally, chocolate’s sweet and fatty nature is reported to stimulate the hypothalamus, which induces pleasurable sensations and affects the levels of serotonin in the brain11, hence enhancing sexual drive.12 Finally, chocolate has been shown to contain unsaturated N-acylethanolamines, which may activate cannabinoid receptors in humans or increase endocannabinoid levels, resulting in heightened sensitivity and euphoria.12 Over the past decade, however, associations between chocolate consumption and hypertension, diabetes, sexual weakness and CVD have also grown steadily, appearing to be supported by basic, clinical and epidemiological research. As the approach to treating these diseases is through pharmacological agents, lifestyle adjustment and dietary modification, the identification of foods with aphrodisiac qualities and/or cardiovascular health benefits and the understanding of how these food components influence normal human physiology could hold a promise of benefit for the consumer. This review discusses current information relating to the acclaimed aphrodisiac and other beneficial health implications of cocoa and chocolate consumption based on epidemiological, preclinical and clinical studies conducted over the past decade. Chemistry and composition of cocoa flavonoids Cocoa and its derived products – chocolate and cocoa powder – are rich in flavonoids, which are characterised as flavan-3-ols or flavanols, and include the monomeric forms, (-)-epicatechin and (-)-catechin, and the oligomeric form of the monomeric units, the procyanidins (Figure 2).9,13,14 Figure 1: Typical cocoa trees with fruit pods at various stages of ripening (-)-epicatechin (+)-catechin procyanidin (4β->6) dimers Figure 2: Chemical structure of the major cocoa flavanols: (-)-epicatechin and (+)-catechin, and procyanidin Invited Review: Cocoa and chocolate consumption 109 Invited Review: Cocoa and chocolate consumption 2008;21(3)S Afr J Clin Nutr These flavonoids are stored in the cotyledon pigment cells of the cacao bean, the fruit of the cacao tree (Theobroma cacao), and are differentiated into three main groups: catechins or flavan-3-ols (about 37%), anthocyanins (about 4%), and proanthocyanidins (about 58%). Less abundant is (+)-catechin, while only traces of (+)-gallocatechin and (-)-epigallocatechin are present. The anthocyanin fraction is dominated by cyanidin-3-α-L-arabinoside and cyanidin-3-ß- D-galactoside. Procyanidins are mostly flavan-3,4-diols and are 4-to-8 or 4-to-6-bound to form dimers, trimers or oligomers, with epicatechin as main extension sub-unit.15,16 The flavonoids represent a ubiquitous and abundant group of polyphenols consumed in the diet primarily from fruits, vegetables and/or plant products. They act as antioxidants due to their free radical scavenging properties, their ability to reduce the formation of free radicals and their ability to stabilise membranes by decreasing membrane fluidity.17,18 These antioxidant properties may contribute to the mounting evidence that a diet rich in fruits and vegetables reduces the risk of CVD.9 Metabolic and epidemiological studies indicate that the regular intake of such products increases the plasma level of antioxidants, a desirable attribute as a defence against reactive oxygen species (ROS). The antioxidants in cocoa can also prevent the oxidation of low-density lipoprotein (LDL) cholesterol, which is related to the mechanism of protection in heart disease. Few studies, however, have shown that ROS associated with carcinogenic processes is also inhibited.14,19,20 The fats from cocoa (cocoa butter) are moreover mainly stearic triglycerides (C18:0), which are less well absorbed than other fats and tend to be excreted in the faeces. They are thus less bioavailable and have a minimal effect on serum cholesterol.9,13 Many investigators have identified the common classes and food sources of flavonoids as including flavanol (quercetin, kaempferol and myricetin [in onions, apples, tea and red wine]), isoflavones (daidzein and genistein [in soy]), flavan-3-ols or flavanols (catechin and epicatechin [in tea, chocolate and red wine]), flavanones (naringenin and hesperitin [in citrus fruits]), flavones (apigenin [in celery], luteolin [in red pepper]) and anthocyanins (in the pigments of red fruits, such as berries and red grapes).14 These different classes of flavonoids are based on their level of oxidation in the basic flavonoid structure (C6-C3-C6), a 15-carbon atom structure arranged in three rings (two aromatic rings on the ends with an oxygenated heterocycle in the middle). Evidence from epidemiological studies suggests that a high intake of dietary flavonoids may reduce the risk of coronary heart disease.13,21,22 Flavonoids have also been reported to have benefits for oxidative stress, vascular function, platelet function and immune response, which may collectively be involved in the process of atherogenesis. Chocolate types and their major nutritional constituents Chocolate is a dense suspension of solid particles, with an average solids concentration of about 60 to 70% from sugar, cocoa and milk (depending on the type) dispersed in a continuous fat phase, which consists mostly of cocoa butter. The main chocolate categories are dark, milk and white (Figure 3), differing in their content of cocoa solid, milk fat and cocoa butter. The outcome is varying proportions of carbohydrate, fat and protein content (Table I). Cocoa refers to the non-fat component of cocoa liquor (finely ground cocoa beans) used in chocolate manufacture in the form of cocoa liquor (containing about 55% cocoa butter) or cocoa powder (about 12% fat), with the addition of sugar, cocoa butter and/or milk. Apart from chocolate, other cocoa products include cocoa powder consumed as a beverage, which is very popular in most African countries. Despite the varied chemical contents, cocoa and chocolate consumption makes a positive contribution to human nutrition through the provision of the macronutrients for energy and other metabolic functions. Chocolate also contains minerals, specifically potassium, magnesium, copper and iron. In addition, cocoa and chocolate fat contain many fatty acids, which are triglycerides dominated by saturated stearic, palmitic and monounsaturated oleic24,25 and all of which appear to have a neutral effect on blood-lipid levels. They do not, in other words, raise blood-cholesterol levels. The antioxidants in cocoa, principally polyphenols including flavonoids such as epicatechin, catechin and notably the procyanidins, are also thought to provide added medicinal and health benefits. White chocolate, however, differs from milk and dark through the absence of cocoa solids, which contain antioxidants, and thus makes little or no contribution to the potential polyphenol-induced improvements in human health. It is also important to note that most dark chocolate contains higher amounts of antioxidant cocoa flavanols than does milk chocolate. A 40-g serving of milk chocolate, for example, provides 394 mg of cocoa flavonoids, whereas dark chocolate contains 951 mg. A hot cocoa mix, in contrast, contains 45 mg of cocoa flavonoids in a 240-mL serving.14,22 These numbers represent typical cocoa flavonoid concentrations and depend on the chocolate-processing Table I: Major constituents of dark, milk and white chocolate23 Product Carbohydrate (%) Fat (%) Protein (%) Dark chocolate 63.5 28.0 5.0 Milk chocolate 56.9 30.7 7.7 White chocolate 58.3 30.9 8.0 Dark chocolate Milk chocolate White chocolate Figure 3: Packs of chocolates containing mixtures of the major types (dark, milk and white) Invited Review: Cocoa and chocolate consumption 110 Invited Review: Cocoa and chocolate consumption 2008;21(3)S Afr J Clin Nutr methods, which may reduce or retain the amount of flavonoids derived from the cacao bean. Judging from reported research on cocoa and chocolate, milk chocolate has been less of an object of investigation than dark (black) chocolate. The reason for this is that the amounts of polyphenols in milk chocolate are smaller than in dark chocolate due to the lower amount of cocoa liquor used in milk chocolate (about 10±15%) compared with that of dark chocolate (about 30±50%). In addition, milk proteins, especially caseins, which are relatively proline-rich, may impair the absorption of procyanidins due to complexation.13 Dark chocolate thus seems a priori to have higher potential as being the most beneficial to human health. Antioxidant properties and their mechanism of action Cocoa powder and chocolate have been shown to have antioxidant potential and to inhibit LDL oxidation in vitro.26 Studies show that the ingestion of a single bolus of cocoa or chocolate increases the antioxidant capacity of plasma, decreases the formation of plasma 2-thiobarbituric acid-reactive substances (TBARS), increases insulin sensitivity and inhibits LDL oxidation ex vivo.26–30 Recent evidence suggests that the long-term consumption of cocoa polyphenols also increases the antioxidative capacity of plasma.31 Studies dealing with the effects of the long-term consumption of chocolate on lipid peroxidation in vivo, however, are scarce and therefore warrant further investigation. Several approaches have been used to investigate the mechanism of the action of cocoa flavanoids. These include preclinical, clinical and in vitro studies predominantly for their effects on the vascular system, with nitric acid (NO) concentration being the central target (Figure 4), and for their effects on endothelial function*, which are thought to be a good biomarkers for estimating coronary-disease risk.9 In vitro cocoa procyanidins have been shown to be antioxidative and to be chelators of copper and iron, thereby preventing LDL from oxidising. Procyanidins also inhibit cyclo-oxygenase 1 and 2 (COX-1 and COX-2) and lipoxygenase. By enhancing the levels of NO, which has been identified as the endothelial-derived relaxing factor and is derived from constitutive endothelial nitric oxide synthase, procyanidins could cause vasodilatation.13 Romanczyk and co- workers16 suggest that, although the polyphenolic compounds inhibit the oxidation of LDL, the more comprehensive consequence is their multidimensional effects on atherosclerosis via NO. The beneficial effects of NO modulation include the regulation of blood pressure and the lowering of NO-affected hypercholesterolaemia and monocyte adhesion, all of which are involved in the progression of atherosclerosis. Many clinical trials have also shown improved epithelial function after chocolate consumption, with neutral effects on total serum cholesterol.14,32–34 Other effects related to CVD risk include the inhibition of platelet activation and aggregation.35–37 This is due probably to the high content of stearic acid (~30% of fatty acids), which is considered to be neutral with respect to total and LDL cholesterol. The consumption of cocoa or dark chocolate may also benefit serum lipids. In a recent study, the consumption of cocoa with dark chocolate increased the serum concentration of high-density lipoprotein (HDL) cholesterol by 4% as a result of the antioxidant properties of flavonoids, which may account partially for the protective effect. The oxidative modification of LDL also plays an important role in atherogenesis. Agents that can prevent LDL oxidation in the arterial wall have furthermore been noted to delay the onset of atherosclerosis in humans.9,33,35 Figure 4: Role of cocoa polyphenols on the vascular system, with nitric oxide (NO) as the target (eNOS = endothelial nitric oxide synthase) 9 Cocoa polyphenols Oxidative stress Superoxide NOArginine eNOS Peroxinitrite Cardiovascular risks Endothelial dysfunction Lipoprotein oxidation Platelet aggregation Inflammation * Lipoprotein oxidation, platelet aggregation and inflammation Invited Review: Cocoa and chocolate consumption 111 Invited Review: Cocoa and chocolate consumption 2008;21(3)S Afr J Clin Nutr Effects on endothelial function, blood pressure and the cardiovascular system Investigators have recently focused on flavan-3-ols as bioactive compounds, particularly with respect to their beneficial effects on endothelial function, blood pressure and cardiovascular function. Many of these studies report that cocoa and chocolate consumption is associated with short-term improvement in the delayed oxidation of LDL cholesterol31, with improved endothelial function34,38, with lowered blood pressure39, with increased insulin sensitivity30 and with improved platelet function.36,37,38 A recent 15-year epidemiological study of elderly Dutch men showed that blood pressure was significantly lowered in the group consuming cocoa or chocolate. The group with the highest cocoa and chocolate consumption was also reported to have a lower incidence of death due to CVD compared with men who did not consume cocoa or chocolate.40 Taubert and colleagues41 also state that small amounts of commercial cocoa confectionary conveyed similar blood pressure-lowering potential compared with comprehensive dietary modifications that have a proven efficacy to reduce cardiovascular-event rate. They explain that, whereas long-term adherence to complex behavioural change is often low and requires continuous counselling,42,43 the adoption of small amounts of flavanol-rich cocoa in the habitual diet is a dietary modification that is easy to adhere to and that therefore may be a promising behavioural approach to lower blood pressure in individuals with above-optimal blood pressure. Although chocolate and cocoa consumption is reported to have benefits for lipid peroxidation ex vivo and for the serum concentration of HDL,14,17 very few long-term studies on effects on lipid peroxidation in vivo have been published. Previous studies have shown that the concentration of serum HDL cholesterol and the oxidative modification of LDL play an important role in the pathogenesis of atherosclerosis,15,37–40 with reports that the consumption of cocoa or chocolate may benefit both these factors in humans. In many of these studies, the consumption of cocoa and dark chocolate was reported to increase the concentration of HDL cholesterol and plasma antioxidant capacity31,44,45 and to decrease the formation of lipid oxidation products (TBARS).44,45 In another study, Mursu and colleagues47 found that the concentration of HDL cholesterol increased in healthy humans ingesting chocolate that contained cocoa mass. The increase in HDL cholesterol was 11% after the consumption of dark chocolate and 14% after the consumption of dark chocolate enriched with cocoa polyphenols, whereas no effect was observed after the consumption of white chocolate. The ratio of LDL:HDL also changed in a similar manner, suggesting that, because the fatty-acid content in the study chocolates was identical, it was the compounds in the cocoa mass that were responsible for the increase in HDL cholesterol. Data documenting the benefit on HDL concentration are supported by a recently reported, long-term crossover study. In this study, Wan and colleagues31 found that, after the daily consumption of 22 g of cocoa powder and 16 g of dark chocolate for four weeks, the concentration of HDL cholesterol was 4% higher compared with the control diet (an average American diet). The higher amount of chocolate ingested (75 g or the equivalent of two candy bars) may explain the greater increase in the HDL cholesterol (11 to 14%) reported by Mursu and colleagues.47 A high concentration of HDL cholesterol has been shown to decrease the risk of CVD.48 The concentration of HDL cholesterol can usually also be increased by 10 to 15% through a change in lifestyle behaviour but this strategy is not suitable for everyone, since it can be meaningfully achieved only by vigorous exercise or moderate alcohol consumption.49 The consumption of chocolate also significantly inhibited the oxidation of LDL in vivo, as measured in the formation of conjugated dienes. The decrease in LDL peroxidation in these study groups indicates the likelihood of this effect being due to the fatty acids in chocolate. It has previously been reported that, compared with polyunsaturated fatty acids, monounsaturated fatty acids inhibit lipid peroxidation.50–53 A high consumption of saturated or monounsaturated fat in the form of chocolate may thus modify the lipid content of LDL to make it more resistant to oxidation by increasing the amount of monounsaturated and saturated fats and by decreasing the amount of polyunsaturated fatty acids. Effects on insulin sensitivity and carcinogenic properties Cocoa and dark-chocolate consumption has been claimed to protect the vascular endothelium by augmenting NO availability and thereby improving endothelium-dependent vasorelaxation.54-57 In an attempt to expand on these findings, Grassi and colleagues30 studied the effects of the consumption of either dark or white chocolate on the homeostasis model assessment of insulin resistance and the quantitative insulin sensitivity check index in 15 healthy young adults with typical Italian diets. These diets were supplemented daily with 100 g of dark chocolate or 90 g of white chocolate, each of which provided 480 kcal. The polyphenol contents of the dark and white chocolate were assumed to be 500 and 0 mg, respectively. Dark-chocolate ingestion not only proved to decrease blood pressure but also to improve glucose metabolism and insulin sensitivity in the subjects. They therefore proposed that it was polyphenol-rich dark chocolate – not white chocolate (which contains mainly sugar and cocoa butter) – that decreased blood pressure and improved insulin sensitivity. In another study, Romanczyk and colleagues16 examined the anti- carcinogenic properties of cocoa extracts using several human cancer-cell lines. Interestingly, the effects were seen only with oligomeric procyanidins and, of these, in particular, with oligomers of 5±12 sub-units, with the most effective being the pentamer. It was suggested that the mechanisms by which procyanidins exert anti-carcinogenic activity include the inhibition of DNA-strand breaks, DNA-protein cross-links and the free radical oxidation of nucleotides due to their antioxidative activity as well as the inhibition of the activities of COX-2 and DNA topoisomerase II. Procyanidins moreover modulate NO production through macrophages, which possess an inducible nitric oxide synthase (iNOS) and thereby affect ribonuclease reductase, the enzyme that converts ribonucleotides into deoxyribonucleotides necessary for DNA synthesis. The inhibition of DNA synthesis may be an important way in which macrophages and other tissues possessing iNOS can inhibit the growth of rapidly dividing tumour cells or infectious bacteria. These findings indicate that cocoa and dark-chocolate consumption may exert an anti- carcinogenic activity in human cells and offer protective action to the vascular endothelium by improving insulin sensitivity, thereby exerting favourable metabolic effects in humans, with further protection against CVD. Since these findings cannot be generalised for all populations, large-scale trials are obviously needed to confirm Invited Review: Cocoa and chocolate consumption 112 Invited Review: Cocoa and chocolate consumption 2008;21(3)S Afr J Clin Nutr these potentially protective actions of dark chocolate or other flavanol-containing foods in populations affected by insulin-resistant conditions, such as essential hypertension and obesity. Cocoa, chocolate and aphrodisiac properties Cocoa and chocolate have been reported to exert several effects on human sexuality, acting mainly as an effective aphrodisiac, increasing sexual desire and improving sexual pleasure.58 They have been claimed to contain a chemical substance known as phenylethylamine, which has been reported to stimulate the hypothalamus, inducing pleasurable sensations as well as affecting the levels of two neurotransmitters – 5-hydroxytrytamine (serotonin) and endorphins in the brain – hence enhancing mood lifting and sexual drive.11 These chemicals occur naturally and are released by the brain into the nervous system during situations of happiness and feelings of love, passion and/or lust. This causes a rapid mood change, a rise in blood pressure, an increase in heart rate and an inducement of those feelings of well-being bordering on euphoria that are usually associated with being in love. In other studies, the cocoa in chocolate has been reported to contain several potentially psychoactive chemicals, such as the sympathomimetic biogenic amines (tyramine and phenylethylamine) and the methylxanthines (theobromine and caffeine).59,61 Spampinato62, for example, notes that each 100 g of chocolate contains 660 mg of phenylethylamine (C 6 H 5 (CH 2 ) 2 NH 2 ), a stimulant similar to the body’s own dopamine and adrenaline. Phenylethylamine has been noted to raise blood pressure and heart rate, heightening sensations and blood-glucose levels.63 Since eating chocolate gives an instant energy boost and an increase in stamina, it is no wonder that the effects of eating chocolate have given chocolate a reputation as an aphrodisiac. Both compounds can also be mildly addictive, which explains the drive of chocoholics. Women are more susceptible to the effects of phenylethylamine and serotonin than men,58 which explains why more women tend to be chocoholics than men. Chocolate has also been shown to contain unsaturated N-acylethanolamines, which may activate cannabinoid receptors or increase endocannabinoid levels and result in heightened sensitivity and euphoria.12 Researchers believe that chocolate contains pharmacologically active substances that have the same effect on the brain as marijuana and that these chemicals may be responsible for certain drug-induced psychoses that are associated with chocolate craving.10,63 Marijuana’s active ingredient leading a person to feel “high” is tetrahydrocannabinol, however, a different chemical neurotransmitter produced naturally in the brain called anandamide has been isolated from chocolate.12 Because the amount of anandamide found in chocolate is so minuscule, this is not the reason for chocolate giving a person a “high”; rather, it is the compounds such as unsaturated N-acylethanolamines in chocolate that have been associated with the good and “high” feeling that chocolate consumption provides. Anandamide is nevertheless broken down rapidly into two inactive sections after production by the enzyme hydrolase, which is found in our bodies.12 Other chemicals are present in chocolate, however, which may inhibit this natural breakdown and thus make people feel good for longer when they eat chocolate. Although chocolate contains chemicals that are associated with feelings of happiness, love, passion, lust, endurance, stamina and mood lifting, scientists continue to debate whether it should be classified as an aphrodisiac. It would be very challenging to say that there is firm proof that chocolate is indeed an aphrodisiac. Chocolate does, however, contain substances that increase energy, stamina, mood lifting and feelings of well-being. The reality is that a gift of chocolate is a familiar courtship ritual that makes people feel good and that induces feelings of being in love. In conclusion, cocoa and chocolate flavonoids are compounds that are vital to human health This is evidenced by their influence on a number of findings related to their biochemical and physiological functions in the body, with identified potent antioxidant effects under in vitro conditions and in vivo after consumption. These antioxidant properties have been related to increases in plasma epicatechin concentrations, to endothelial-dependent vascular relaxation as promoted by cocoa flavonoids due in part to the increased bioavailability of NO and prostacyclin, and to the anti-atherosclerotic properties of NO combined with a favourable shift toward vasodilation, which confers a vasculo-protective effect. The lowering of blood pressure has also been found after short-term dark-chocolate intervention in the presence of mild isolated systolic hypertension. Other known effects from cocoa flavonoids include their suppressive effect on platelet reactivity and platelet-related primary haemostasis, the modulation of immune function, and inflammation as potential cardioprotective effects. Finally, some aphrodisiac effects, mood lifting and heightened sensitivity have also been reported to be due to phenylethylamine and N-acylethanolamine compounds in cocoa and chocolate. As consumers become more aware of the potential aphrodisiac effects and health benefits associated with cocoa and chocolate consumption, they will require more information on whether the intake of these functional compounds and/or their sources is related to measurable effects on human sexual lives, health and/or the development of disease. They will also require relevant information on specific sources and products commonly available in the marketplace as a guide to their selection of foods. 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Hurst WJ, Martin RA, Zoumas BL, Tarka SM. Biogenic amines in chocolate – a review. Nutrition Reports International 1982; 26: 1081–1086. 61. Max B. This and that: chocolate addiction, the dual pharmacogenetics of asparagus eaters, and the arithmetic of freedom. Trends in Pharmacological Sciences 1989; 10: 390–393. 62. Spampinato C. Chocolate: food of the gods. http://www.carnegiemuseums.org/ cmag/bk_issue/1997/ janfeb/dept6.htm, 2007. 63. Rozin P. Chocolate craving and liking. Appetite 1991; 17: 199–212. work_apvxqqriejhtta7eloskksyqbq ---- EDITORIAL Meet the contributors Nicola Oberbeckmann-Winter Published online: 12 December 2014 # Springer-Verlag Berlin Heidelberg 2014 This special issue celebrates the 13th Anniversary of Analyt- ical and Bioanalytical Chemistry (ABC) by highlighting cur- rent research from the Editorial Board of ABC. The strong commitment and dedication of the Editors and International Advisory Board have been of enormous value in establishing ABC as an international journal for rapid publication and global visibility of analytical research. In preparing this 13th Anniversary Issue, we are grateful for the overwhelming support we have received and thank all contributors for generously providing ex- cellent research articles, critical reviews, and trend arti- cles from the forefront of their research. Below, we invite you to meet those who contributed to this excep- tional issue. Marco Aurélio Zezzi Arruda is Full Professor at the University of Campinas—Unicamp (Campinas, Brazil), Department of Analytical Chemistry; Head of the Department of Analytical Chemistry, Institute of Chemistry, Unicamp; Head of the Sample Preparation, Spectrometry and Mechanization group— GEPAM; and a member of the ad- visory board of the National Institute of Science and Technology—INCT, for Bioanalytics. He is a member of the editorial staff or advisory board of Analytical and Bioanalytical Chemistry, Metallomics, Journal of Integrated Omics, and Brazilian Journal of Analytical Chemistry; a member of the advisory board of the Brazilian Mass Spectrometry Society (BrMASS) and Brazilian Chemistry Associa- tion (ABQ); and he is a coordinator of the inorganic mass spectrometry area of the BrMASS. His current research interests include trans-disciplinary work, involving speciation analysis and comparative omics of plants (i.e., soybean, sunflower, Arabidopsis Thaliana) and human bodily fluids (i.e., blood serum, urine, saliva) to identify possible biomarkers for transgenic species and human diseases, as well as to evaluate the production of reactive oxygen species, and (metallo)proteins responses under stress in a given system. He is the author or co-author of over 170 research articles, 5 book chapters, 5 patents, over 35 invited lectures at national/international meet- ings, and the editor of 1 book. Additionally, he has over 3100 citations in the literature and an h index of 30. Craig A. Aspinwall is an Associate Professor in the De- partment of Chemistry and Biochem- istry at the University of Arizona. His research focuses on the development and application of optical and electro- physiological sensors and microscale separations for the analysis of biolog- ical systems. He is a recipient of the ACS Division of Analytical Chemis- try Award for Young Investigators in Separation Science (2009) and was an inaugural ACS GREET (Global Re- search Experiences, Exchanges, and Training) Scholar (2011). Antje Baeumner is Director and Professor of the In- stitute of Analytical Chemistry, Chemo and Biosensors at the Uni- versity of Regensburg. Until 2013 she was Professor of Biological En- gineering at Cornell University, where she started her tenure-track career as Assistant Professor in 1999 and, to date, remains active on the faculty. Her research focuses on the development of lab-on-a- chip devices and paper-based bio- sensors for the detection of pathogenic organisms and toxins. She has received numerous awards for her teaching and research, including the State University of NY Chancellor’s Award in Excellence in Teaching, an Alexander-von-Humboldt Research Fellowship, and a DFG Mercator Visiting Professorship, as well as being a finalist for the Blavanik Award for Young Scientists. Published in the topical collection celebrating ABCs 13th Anniversary. N. Oberbeckmann-Winter (*) Analytical and Bioanalytical Chemistry, Springer, Tiergartenstrasse 17, 69121 Heidelberg, Germany e-mail: abc@springer.com Anal Bioanal Chem (2015) 407:629–635 DOI 10.1007/s00216-014-8348-9 Damià Barceló Cullerés is Full Research Professor and Dep- uty Director at IDAEA-CSIC and, since 2008, Director of the Catalan Institute for Water Research (ICRA). Since 2009, he has been Visiting Professor at King Saud University, Riyadh, Saudi Arabia. Apart from receiving the renowned King Jaime I Award from the Generalitat of Valencia (Spain) for the Protection of Nature in 2007, he also received the Prince Sultan Bin Abdulaziz International Prize for Water and the Recipharm Environmenal Award in 2012. His research interests are in environmental analysis and the fate and behavior of organic pollutants in water, sediment, and biota, using mass spectrometric techniques, immunoassay, toxic assays, and biosensors. In recent years, his interests have also included bridging environmental and health risks in the field of emerging contaminants. Maria Careri has been Full Professor of Analytical Chemistry at Parma University since 2001 and Head of the Chemistry De- partment at the same University since 2012. She has also been Director of the University Master Course Chem- istry Laboratory Quality Systems since 2002 and Director of the Na- tional School of “Analytical and Bioanalytical Methodologies Based on Mass Spectrometry” of the Italian Chemical Society from 2005. For the past 10 years, her research activities have centered on the development of novel materials for solvent-free extraction techniques for food safety and environmental monitoring and development of innovative methods for structural and functional proteomics using mass spectrometry based tech- niques. Her current research interests include the development of novel materials for desorption electrospray ionization and matrix-assisted laser desorption ionization mass spectrometry techniques and the developments of biosensors for diagnostic purposes. She is the author of more than 160 scientific papers in international peer-reviewed journals and of more than 250 communications at national and international symposia. Rafael Cela is Professor of Analytical Chemis- try at the University of Santiago de Compostela, Spain, leading a re- search group on chromatography and chemometrics in the Laborato- ry for Analytical Chemistry at the Research Institute of Food Analy- sis of that university. His research has focused on the analytical appli- cation of separation science and particularly on the development and optimization of sample prepa- ration microtechniques for chro- matographic analysis, including experimental design and the development of computer-assisted chro- matographic methods and sample handling strategies. He is the author of more than 250 scientific papers and several textbooks. Jörg Feldmann, a Feodor Lynen Fellow (Alexander von Humboldt Foundation), is cur- rently Head of Chemistry at the Uni- versity of Aberdeen (UK), where he has been the Chair in Environmental Analytical Chemistry and Director of TESLA (Trace Element Specia- tion Laboratory) since 1997. He has pioneered the simultaneous hyphen- ation of ICPMS and ESI-MS to HPLC for the determination of labile metal (mainly arsenic) biomolecule interactions, which are crucial for explaining environmental and bio- logical processes. In addition, he developed laser ablation ICPMS for dynamic bioimaging of elements in biological tissues from trace experi- ments. He is the author or co-author of more than 190 peer-reviewed publications. Günter Gauglitz is Senior Professor at the Eberhard- Karls-University of Tübingen work- ing in analytical and physical chem- istry. He was chairman of the GDCh Division of Analytical Chemistry and chaired the Europt(r)ode VIII meeting. For more than 15 years, his main scientific interests have centered on research and develop- ment in chemical and biochemical sensors with a special focus on the characterization of interfaces of polymers and biomembrane sur- faces, spectroscopic techniques, the use of spectral interferometry to monitor changes in the optical thickness of thin layers, and the effects of Fresnel reflectivity at interfaces. He has been an Editor of Analytical and Bioanalytical Chemistry (ABC) since 2002. Heidi Goenaga-Infante joined LGC as a Senior Researcher in speciation analysis in 2003. She is currently Principal Scientist and Team Leader of the Inorganic Anal- ysis team within the Science and Innovation Division. Her team ex- pertise lies in trace element specia- tion analysis, metallomics research, size-based element fractionation, high-accuracy bulk and spatial ele- mental and isotope ratio analysis, and the characterization of speciated reference materials and standards. She is the UK representative at the Inorganic Analysis Working Group of the CCQM (the International Consultative Committee for Metrology in Chemistry). She is also a member of the advisory board of Metallomics, a member of the editorial board of JAAS, and a member of IUPAC. She currently coordinates the EU project NanoChop (Chemical, Optical and Physical Characterisation of Nanomaterials in Biological Samples) and leads work packages within the EU projects “Metrology for Metalloproteins” and “Traceability of Mercury Measurements in the Environment”. 630 N. Oberbeckmann-Winter Michal Holčapek is Full Professor of Analytical Chem- istry at the Department of Analytical Chemistry, University of Pardubice, Czech Republic. His research interests are mass spectrometry and LC/MS with applications in the lipidomic analysis of various types of lipid iso- mers, the lipidomic quantitation of bi- ological samples, and the search for lipid biomarkers of serious human dis- eases. He is the co-author of 106 pa- pers with an h index of 30. He is also editor of the book ‘Extreme Chroma- tography: Faster, Hotter, Smaller’ and of special mass spectrometry volumes in Journal of Chromatography A, as well as of the lipidomics virtual issue in Analytical Chemistry. He is also on the Power List of the 100 most influential people in the analytical sciences presented by The Analytical Scientist. Marilyn A. Huestis is Chief of Chemistry and Drug Me- tabolism, National Institute on Drug Abuse, National Institutes of Health. Her main research interests are the pharmacology of cannabinoid ago- nists and antagonists, in utero drug exposure, and the many new psy- choactive substances that are the current face of drug abuse. She has published 348 peer-reviewed manu- scripts, and more than 500 abstracts. She has received many awards, including the Distinguished Fellow of the American Academy of Forensic Sciences (AAFS), Australian Distin- guished Visiting Scholar, Inspiring Minds in Clinical Chemistry, Alan Curry Lifetime TIAFT Achievement Award, Doctor Honoris cause from University of Helsinki Faculty of Medicine, Outstanding Contributions in Research from AACC, Irving Sunshine Award from IATDMCT, and the Rolla N. Harger Forensic Toxicology Award from AAFS. Maciej Jarosz is Chair of Analytical Chemistry, Fac- ulty of Chemistry, Warsaw University of Technology, Poland; a former Vice President and Treasurer of the Polish Chemical Society; a member of the board of the Committee on Analytical Chemistry, Polish Academy of Sci- ences; a national representative in the Division of Analytical Chemistry of IUPAC; and a member of the Steering Committee of the Division of Analyt- ical Chemistry of EuCheMS. He is the author or co-author of about 100 orig- inal papers and chapters in mono- graphs, and has given more than 200 lectures and made other contributions to scientific conferences. His scientific interests focus on cultural heritage preservation (identification of natural products in art works), food and phar- maceutical analysis, and environmental speciation analysis. He was awarded (among others) with an Honored Award of the Polish Chemical Society and the Prof. Andrzej Waksmundzki Medal from the Committee on Analytical Chemistry, Polish Academy of Sciences Award. Kiyokatsu Jinno is currently Professor Emeritus and Guest Professor at the Department of Environmental and Life Sciences, Toyohashi University of Technolo- gy, Japan. His research interests fo- cus on the miniaturization of analyt- ical separation systems and sample preparation. He has received various awards, such as the Golay medal. Uwe Karst obtained his Ph.D. in Analytical Chemistry from the University of Münster, Germany, in 1993, and was a Postdoctoral Research Asso- ciate at the University of Colorado in Boulder, CO, USA. After his return to the University of Münster, he finished his Habilita- tion in 1998. In 2001, he took over a position as Full Professor of Chemical Analysis at the Uni- versity of Twente, The Nether- lands. He accepted his current po- sition as Chair of Analytical Chemistry at the University of Münster in 2005. His research interests focus on hyphenated analytical tech- niques and their (bio)medical and pharmaceutical applications, includ- ing elemental speciation analysis, metallomics, mass spectrometric imaging, and electrochemistry/MS. David A. Keire is a Research Chemist in the Di- vision of Pharmaceutical Analy- sis within the Center for Drug Evaluation and Research at the US Food and Drug Administra- tion. He is an analytical chemist with expertise in NMR spectros- copy. His focus at the US FDA is on the application of modern analytical methods to the assess- ment of drug quality. His current work includes studies on the comparison and characterization of complex carbohydrate drugs, protein therapeutics, and mono- clonal antibodies. Meet the contributors 631 Rudolf Krska is Full Professor for (Bio-) Analytics and Organic Trace Analysis and is Head of the Department for Agrobiotechnology, IFA Tulln, with more than 170 co-workers at the Uni- versity of Natural Resources and Life Sciences, Vienna (BOKU). In 2009/2010, he worked for 1 year as Chief of Health Canada’s Food Re- search Division in Ottawa. He has received 6 scientific awards and is (co-)author of more than 200 SCI pub- lications (h index of 39). His cur- rent research interests are in the area of plant–fungi metabolomics and mycotoxin determination by novel mass spectrometric and infrared based techniques. Aldo Laganà has been Full Professor of Analyti- cal Chemistry at the Faculty of Sci- ences of Sapienza University of Rome since 2002 and Head of the Chemistry Department since 2003. His research activities are focused on the development and validation of novel analytical methods by means of advanced mass spectro- metric instrumentation (such as LC–MS/MS and nanoLC-HRMS with Orbitrap technology) for char- acterization and quantification of natural and anthropogenic sub- stances (e.g., flame retardants, pesticides, mycotoxins, polyphenols, phytoestrogens, estrogens, and other endocrine disrupter compounds) in environmental, food, plant, and biological matrices. In recent years, he has also turned his attention to proteomics and metabolomic studies, as well as to the interactions between biomolecules and nanoparticles for gene/drug delivery. Frances S. Ligler, Dr.Phil., Dr.Sc., is the Lampe Dis- tinguished Professor of Biomedical Engineering at the University of North Carolina at Chapel Hill and North Carolina State University, Se- nior Scientist Emerita at the US Na- val Research Laboratory, and a Member and Councilor of the US National Academy of Engineering. Currently working in the fields of biosensors and microfluidics, she has also performed research in bio- chemistry, immunology, and tissue engineering. She has over 375 full-length publications and patents, which have led to 11 commercial biosensor products, and she has been cited over 12,000 times (h index of 64). Her major awards include the 2003 Homeland Security Award from the Christopher Columbus Foundation; the 2003 Presidential Rank of Distinguished Senior Professional from President Bush; the 2012 Presidential Rank of Meritorious Senior Pro- fessional from President Obama; and an honorary doctorate from the Agricultural University of Athens, Greece, in 2014. Wolfgang Lindner is an expert in separation technolo- gies with a focus on molecular rec- ognition phenomena in separation sciences, life-science analysis, and materials science, as well as devel- oping diverse stationary phases with dedicated selectivity properties. Among these stationary phases, the chiral stationary phases (CSPs) have become the most widely known. He is the author and co-author of more than 440 publications, leading to >10,000 citations. Among other prizes, he has received the Chirality Medal, the A.J.P. Martin Gold Medal, the Halasz Medal, the ACS Award for Chromatography, the CaSSS Award for outstanding achievements in separation science, and very recently the Nernst-Tswett Award from the European Society of Separa- tion Sciences (EuSSS). R. Kenneth Marcus is Professor of Chemistry at Clemson University, where he has served on the faculty since 1986. His research interests are diverse, including the development of capillary-channeled polymers (C-CP) for applications in protein analytics and downstream process- ing, and the implementation of liq- uid sampling–atmospheric pressure glow discharge (LS-APGD) microplasmas as sources for atomic emission and mass spectrometric analyses. His research has resulted in over 170 peer-reviewed publica- tions and yielded 30 Ph.D. graduates. He has been elected as a Fellow of the Royal Society of Chemistry and the American Association for the Advancement of Science. Hans H. Maurer has been Full Professor of Pharma- cology & Toxicology at the Faculty of Medicine and Pharmacy, Saarland University, since 1992, and Head of the Department of Ex- perimental and Clinical Toxicology in Homburg, Germany. He has pub- lished over 260 original papers and been invited to write reviews on his two main areas of research: analyti- cal toxicology (GC-MS, LC-(HR)- MS), and the toxicokinetics and metabolism of xenobiotics. He is a member of the editorial board of various international journals and a member of the executive boards of scientific societies in his field. He has received several international scientific awards, including the title of Doctor Honoris Causa (honorary doctorate) in 2007 from the University of Ghent, Belgium. 632 N. Oberbeckmann-Winter Juris Meija is a Research Officer at the National Research Council, Canada. His research interests encompass the- oretical analytical chemistry, isotope-ratio measurements, and the history of chemistry. He serves as Column Editor for the analytical challenge series in Analytical and Bioanalytical Chemistry and is the Chairman of the IUPAC Commis- sion on Isotopic Abundances and Atomic Weights. Boris Mizaikoff is a Chaired Professor at the Uni- versity of Ulm and Director of the Institute of Analytical and Bioanalytical Chemistry (IABC), Ulm, Germany. His research in- terests include optical chemo-/bio- sensors, infrared spectroscopy and sensing technologies, quantum cascade lasers, multifunctional (nano-)analytical systems, sensor miniaturization, on-chip sensing platforms, integration and micro-/ nanofabrication, focused ion beam based nanofabrication, (bio)chemical molecular recognition schemes for separation and sensing applications, molecularly imprinted materials, environmental analytical chemistry, process analytical chem- istry, and biomedical diagnostics. Maria C. Moreno-Bondi has been Full Professor at the De- partment of Analytical Chemistry of Complutense University since 2008 after receiving her Ph.D. in analytical chemistry from the Complutense University of Madrid (Spain) in 1990. She received the Young Researcher’s Award from the Spanish Society of Analytical Chemistry in 1993 and a Research Award in Analytical Chemistry from the Royal Spanish Society of Chemistry in 2010. Her research interests lie in the development of optical chemical sensors and biosen- sors and their applications to environmental and food analysis, as well as in the development of biomimetic recognition elements for sensing and separation purposes. David C. Muddiman is currently Distinguished Professor of Chemistry and Founder and Di- rector of the W.M. Keck Fourier Transform Mass Spectrometry Lab- oratory at North Carolina State Uni- versity in Raleigh, NC, USA. His research interests include the devel- opment and application of novel chemistries, advanced separations, ionization sources, and mass spec- trometry directed at ovarian cancer research. His group has presented over 500 invited lectures and pre- sentations at national and international meetings, has published over 200 peer-reviewed papers and reviews, and has been awarded 4 US patents. He is the recipient of the 2010 Biemann Medal, American Society for Mass Spectrometry; the 2009 NCSU Alumni Outstanding Research Award; the 2004 ACS Arthur F. Findeis Award; the 1999 American Society for Mass Spectrometry Research Award; and the Safford Award, University of Pittsburgh, for Excellence in Teaching. Valérie Pichon is Full Professor at the UPMC. Since 2009, she has been leading the De- partment of Analytical, Bioanalytical Sciences and Miniaturization, which is part of the UMR Chimie Biologie Innovation. It comprises a team of 30 researchers (permanent staff, postdoc- toral researchers, and PhD students) and is located at the ESPCI ParisTech. She also co-leads the UMR CBI (more than 100 re- searchers). Her major research inter- ests include developing stationary phases based on antibodies or aptamers and molecularly imprinted polymers to selectively extract organic molecules from complex samples, and is always trying to miniaturize these tools. She is the author of more than 90 publications (h index of 32), 5 book chapters, and holds a patent. In 2001, she was awarded the Chemistry Prize of the Analytical Chemistry Department of the French Society of Chemistry. Furthermore, she is currently Vice President of AfSep (Association Française des Sciences Séparatives), the French Association of Separations Sciences. Jürgen Popp studied chemistry at the universities of Erlangen and Würzburg. After receiving his Ph.D. in chemistry, he joined Yale University for post- doctoral work. He subsequently returned to Würzburg University, where he finished his Habilita- tion in 2002. Since 2002, he has held the Chair for Physical Chemistry at the Friedrich- Schiller University Jena. Further- more, since 2006, he has been the Scientific Director of the Leibniz Institute of Photonic Technology, Jena. His research interests are mainly concerned with biophotonics, in particular, the development and application of Meet the contributors 633 innovative Raman techniques for biomedical diagnostics, as well as environmental and food analysis. He has published more than 450 papers in journals and is a fellow of SAS and SPIE. In 2012, he received an honorary doctorate from Babes-Bolyai University Cluj, Napoca, Romania, and in 2013 the Robert-Kellner Lecture Award. Luigia Sabbatini is Full Professor of Analytical Chemistry at the University of Bari Aldo Moro. She has been Head of the Chemistry Department (2005– 2010), President of the Laboratory for Diagnostics in Cultural Heritage, President of the Analytical Chemis- try Division of the Italian Chemical Society (1997–2000), and Italian Representative in the Division of Analytical Chemistry of EuCheMS. She is also on the Editorial Staff or Advisory Board of international journals, and is the co-author of about 170 ISI papers, co-inventor of several international patents, and editor or co-editor of books on surface analysis of polymer materials. Her main scientific interests focus on the development of application-oriented innovative (nano)materials, and on the design of surface architectures for biomedical devices and sensors and their characterization by X-ray pho- toelectron spectroscopy. Recently, she has devoted her attention to the development of nondestructive and noninvasive analytical methodologies for the characterization of samples in the field of cultural heritage. Yoshihiro Saito has been Associate Professor at the Department of Environmental and Life Sciences, Toyohashi University of Technology, Japan, since 2008. He received his Ph.D. in 1996 from the same university. After 2 years as a Postdoctoral Researcher in the USA, he returned to Toyohashi as a Research Associate, and was then promoted to Assistant Professor (2000) and Associate Professor (2008). He received the Young Sci- entist Award from The Society for Chromatographic Sciences (Japan) in 2002 and the Tokai Chemical Industry Award (Japan) in 2004. He has served as Secretary General of The Society of Chromatographic Sciences since 2012 and as Associate Editor of Analytical Sciences (2009–2014). His research interests include the development of micro- scale analytical systems, such as microextraction and microcolumn sep- aration techniques, hyphenated systems based on these techniques, new stationary phase design and synthesis, and the application of fibrous materials to microscale extraction/separation methods. He is the author or co-author of over 130 research papers in separation science. Renato Seeber is Professor of Analytical Chem- istry at the University of Mode- na and Reggio Emilia, Italy. He is the co-author of about 190 scientific publications and chap- ters of books, and has also been editor or co-editor of special is- sues for various journals, such as S e n s o r s , A n a l y t i c a l a n d Bioanalytical Chemistry, and Electrochimica Acta. His current in- terests are in the field of electro- chemical sensing, from the design, realization, and characterization of new materials, devices, and measure- ment procedures, to elaboration of the relevant responses. Previously, he was interested in molecular electrochemistry, in the definition of novel algorithms for simulation and analysis of electrode mechanisms, and in experimental and theoretical studies of equilibria and kinetics of interest in food and soil chemistry. Torsten C. Schmidt is Head of the Department of Instru- mental Analytical Chemistry and the Center for Water and Environmental Research (ZWU) at the University of Duisburg-Essen, and Scientific Di- rector at the IWW Water Centre in Mülheim an der Ruhr. He is currently President of the German Water Chemistry Society. In 2013, he re- ceived the Fresenius Award from the German Chemical Society. His main research interests include the development and application of ana- lytical methods with a focus on separation techniques (GC, LC), sample preparation, compound-specific stable isotope analysis, process-oriented environmental chemistry, and oxidation processes in water technology. Toshimasa Toyo'oka is Full Professor at the School of Pharmaceutical Sciences and the Graduate School of Pharmaceutical Sciences, University of Shizuoka, Japan. He is also Dean of the Gradu- ate School of Pharmaceutical Sci- ences. His major research interests are the development of new chiral derivatization reagents for various functional groups, new analytical methods including high-throughput separations (UPLC and SFC, etc.), highly sensitive detections (FL and MS, etc.) of biomolecules, and bio- marker discovery in noninvasive samples (saliva and hair, etc.) for the diagnosis of disease. He is the author and co-author of over 230 original scientific papers, 20 review papers, and 25 book chapters. In 2011, he received the Society Award from the Japan Society for Chromatographic Sciences. 634 N. Oberbeckmann-Winter Miguel Valcárcel has been Full Professor of Analyti- cal Chemistry at the University of Córdoba since 1976. His master re- search lines have focused on analyt- ical nanoscience and nanotechnolo- gy, and the automatization/minia- turization/quality of (bio-)chemical measurement processes. He is the author and co-author of more than 900 scientific articles, 8 mono- graphs, 10 textbooks, and 20 book chapters. He has been the coordina- tor of 25 Spanish scientific research projects, 14 of which were interna- tional in nature, and of 12 contracts with private firms, and has promoted a spin-off company devoted to nanotechnology. He has been co- supervisor of 75 doctoral theses and invited lecturer at 70 international meetings. He is the recipient of national (e.g., Award in Chemistry in Spain, 2005) and international (e.g., Robert Boyle Medal from the RSC, 2004) scientific prizes, as well as having received the Doctor Honoris Causa from the University of Valencia (Spain). Frank Vanhaecke is Senior Full Professor of Ana- lytical Chemistry at Ghent Uni- versity (Belgium) and has a pas- sion for the determination, speci- ation, and isotopic analysis of (trace) elements by inductively coupled plasma mass spectrome- try (ICP-MS). He leads the Atomic & Mass Spectrometry (A&MS) research group, which studies fundamentally oriented aspects of the technique and de- velops methods for solving challenging scientific problems in an interdisciplinary context. So far, his scientific research has result- ed in more than 250 publications in peer-reviewed journals. In 2011, he received a European Award for Plasma Spectrochemistry for his contributions to the field. He is a Fellow of the Royal Society of Chemistry (RSC) and the Society for Applied Spec- troscopy (SAS). Picture © Cédric Verhelst. Adam T. Woolley is Professor and Associate Chair in the Department of Chemistry and Biochemistry at Brigham Young University in Provo, UT, USA. He is the recipient of a Presidential Early Career Award for Scientists and En- gineers (2006) and the ACS Division of Analytical Chemistry Award for Young Investigators in Separation Science (2007). His current research focuses on three general topics: the development of novel and sophisti- cated integrated microfluidic sys- tems for preterm birth biomarker quantitation, the design of simple miniaturized biomolecular assays, and biotemplated fabrication of nanoelectronic systems. Guowang Xu is the Director of the Metabonomics Research Center in the Dalian Insti- tute of Chemical Physics, Chinese Academy of Sciences. In 2004, he obtained the Distinguished Young Scientists award from the National Natural Science Foundation of China. He was the co-chairman of the 30th ISCC in China, 33rd HPLC in Japan, and 37th HPLC in China, and is a member of the permanent scientific committee of HPLC. His main research interests are in chroma- tography, mass spectrometry, and metabolomics applications in disease biomarker discovery, traditional Chinese medicines, and food safety. Xiangmin Zhang is Professor of Analytical Chemis- try in the Department of Chemistry at Fudan University with a second- ary appointment at the Institutes of Biomedical Sciences in Shanghai, China. He is also a member of the editorial board of Proteomics and the Chinese Journal of Chromatog- raphy. His major research interests include chromatographic separa- tion; developing nanomaterials for the enrichment of proteins/ peptides; and the development of chromatographic techniques, mass spectrometric methods, and hyphenated technologies for proteomic anal- ysis and disease biomarker discovery. He is the author or co-author of over 200 peer-reviewed papers, books, and book chapters. Meet the contributors 635 Meet the contributors work_att52fqi3vcfrca5azgar7ngeq ---- wp-p1m-39.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-39.ebi.ac.uk no 218194210 Params is empty 218194210 exception Params is empty 2021/04/06-02:09:19 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. Message ID: 218194210 (wp-p1m-39.ebi.ac.uk) Time: 2021/04/06 02:09:19 If you need further help, please send an email to PMC. Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_av4bjingizezjcc6k27eydunwy ---- 2nd World Conference on Technology, Innovation and Entrepreneurship (WCTIE-2017), V.5-p.224-233 Yuksel,et al. ___________________________________________________________________________________________ DOI: 10.17261/Pressacademia.2017.593 224 PressAcademia Procedia 2nd World Conference on Technology, Innovation and Entrepreneurship May 12- 14, 2017, Istanbul, Turkey. Edited by Sefer Şener NEW FORESIGHT GENERATION AND FRAMEWORK OF FORESIGHT DOI: 10.17261/Pressacademia.2017.593 PAP-WCTIE-V.5-2017(31)-p.224-233 Nurdan Yuksel 1,2 , Hasan Cifci 1,3 Serhat Cakir 4 1 Department of Science and Technology Policies Studies, Middle East Technical University 3 Turkish Air Force 4 Department of Physics, Middle East Technical University, Çankaya, Ankara, Turkey 2 ASELSAN Inc.,Yenimahalle, Ankara, Turkey *Corresponding Author: nurdan.yuksel@metu.edu.tr ABSTRACT The article starts with various definitions of technology foresight from the literature and new definition is given by the authors. Prominent definitions of foresight are analyzed and given according to their different elements in the literature. By assessing the evolution of foresight as a term and its five generations through time, the foresight of sixth generation is set forth. Based on the literature analysis, foresight generations are grouped into four main categories. Foresight frameworks are analyzed and a generic foresight functional model with nine consecutive phases named ‘FORESIGHT’ is suggested. Functions in the FORESIGHT model are matched with the phases of main foresight frameworks in the literature based on their actions and artifacts within specific phases. It is like a guide for practitioners of which activities are carried out in foresight studies. Keywords: Foresight, foresight framework, foresight generations. 1. INTRODUCTION Humans have a capacity to systematize the estimation of future events [1]. Voros [2] defines the Three Laws of Future based on the suggestion of Amara [3] as it is not predetermined, not predictable and the selection of today affects its outcomes. Since the future itself is a complex subject coming from its uncertain nature, futures oriented studies are difficult to determine and realize. Any statement related with future cannot be confirmed at the time when they are built [4]. It is a challenge or almost impossible to predict the future. Following quotes show the difficulty of predicting the future developments and prove the need a new approach to the future related matters: - "Everything that can be invented has been invented", Charles H. Duell, Commissioner, US Office of Patents, 1899. - "Airplanes are interesting toys, but of no military value", Marshall Foch, 1911. - "There is no reason for an individual to have a computer at home", Ken Olsen, Chairman of Digital Equipment Corporation, 1978. Unlike future as a term, which invokes “looking ahead” [5], futures studies also include “looking back” [6] and looking present. Since futures is very wide subject, there is different terminology about it as futures research, "futures studies", sometimes futures analysis, futurism, futuristics, or even futurology [2]. According to Sardar [5], suffix of –logy in futurology which shows the meaning of certainty and objectivity is not suitable for futures having ambiguity. He mentions about the linguistic and pronunciation difficulty of futuristics and lethality of futurism’s logic which implies that science will provide knowing the future. While Voros [2] prefers to use Futures since the term gives the plurality of different futures, Sardar [5] finds the best suitable term as Future Studies with the same reasoning of Voros. Futures are evaluated as extensive professional and academic area continuing mailto:nurdan.yuksel@metu.edu.tr 2nd World Conference on Technology, Innovation and Entrepreneurship (WCTIE-2017), V.5-p.224-233 Yuksel,et al. ___________________________________________________________________________________________ DOI: 10.17261/Pressacademia.2017.593 225 PressAcademia Procedia to develop with its methods, tools and research [7]. Futures studies are multi-disciplinary, trans-disciplinary and un-disciplinary 1 [5] activities for the future. When looking at the literature, forecast and foresight as future studies come into prominence. While forecast is mainly passive attitude for the single future, foresight is systematic active attitudes of today for diverse futures. Foresight has wider aim such as involvement of broad participation, invoking the policy makers with its outputs [8] and providing greatest economic and social benefits [9]. Forecast is a set of techniques which are used to convert inputs to outputs whereas foresight is mainly a process of which techniques are used to create common understanding, commitment and networking [10]. According to Loveridge [11] foresight is structurally based on the “uncomfortable marriage of well-structured and tested information to its counterpart subjective opinion”. The timeline in Figure 1 shows the history of foresight as a term. Figure 1: Timeline of Foresight as a Term 2 Hines and Gold [12] researched about the foresight profession and assessed its status against the common criteria of profession. Since they concluded that it corresponded the requirements of capacity, field and discipline more or less but it was not able to emerge as profession by 2013. Together with the knowledge economy in globalized world, it is undeniable that science and technology are the major determinants of the future. So, technology foresight becomes the most important type for future studies. Martin [13] defines Technology Foresight (TF) as "A process involved in systematically attempting to look into the longer-term future of science, technology, the economy and society with the aim of identifying the areas of strategic research and the emerging generic technologies likely to yield the greatest economic and social benefits". TF also creates networks between the stakeholders by invoking awareness about opportunities, threads, social and economic needs, benefits or damages. TF studies contribute to knowledge creation by building Ba 3 which is shared extent of the relations emerged from interactions between individuals, groups and environment [14] and filling the Ma 4 which represents the spaces between boundaries of Ba such as disconnection of stakeholders or physical distance between them. TF is just one of the analyses of Technology Future Studies (TFA) or Future oriented Technology Analyses (FTA). Different forms of FTA, which covers emerging technology conditions and types, 1 It consciously rejects the status and state of a discipline while being a fully-fledged systematic mode of critical inquiry. 2 Miles [22] was used in building timeline of foresight. 3 Japanese term come up with by philosopher Kitaro Nishida and developed by Shimizu 4 Japanese word which can be roughly translated as "gap", "space", "pause" or "the space between two structural parts [43]. 2nd World Conference on Technology, Innovation and Entrepreneurship (WCTIE-2017), V.5-p.224-233 Yuksel,et al. ___________________________________________________________________________________________ DOI: 10.17261/Pressacademia.2017.593 226 PressAcademia Procedia technology development paths and their impacts systematically, such as technology forecasting, technology intelligence, technology assessment, technology roadmapping exist concurrently with TF [15]. In Table 1, elements of various foresight definitions in the literature are shown. Elements are listed based on the number of references given. In accordance with the model suggested in this study, a new foresight definition is set forth as follows: “Foresight is a systematic and multidisciplinary process with proper methodology combinations for identifying technological, economic and social areas to prioritize investments and research in order to determine medium or long term future strategies by using all level of resources from organizational to international.” 2.FORESIGHT GENERATIONS Foresight studies can be divided into different generations based on the scope, goals and methods involved within foresight processes. In the literature, there are different approaches which can be categorized under 4 main groups towards generational models of foresight as shown in Figure 2. Linstone [16] classifies foresight generations into three groups based on certain society. I. First generation (ca. 1800 - Industrial Society): Foresight activities were mainly based on technology forecasting which dated back to industrial era with Taylor’s scientific management. Quantitative, semi- quantitative and qualitative tools were developed in order to forecast and predict technological developments. II. Second generation (ca. 1970 - Information Society): Information technology has noteworthy impact in effecting simultaneous centralization and decentralization or globalization and localization. Computer capabilities have been used for forecasting. It has become possible to use vast majority of databases and computer power in order to reach and process huge volumes of data. III. Third generation (ca. 2025 - Molecular Society): This era is founded on molecular level with nanotechnology, biotechnology, and materials science stepping forward. It is also referred to as the Nano-biotechnology era and the Micro and Nanotechnology era (MNT). Nanotechnology is expected to lead to a vast increase in computational power and intelligence which are exploited in foresight methods and activities. As one of the main triggers of the foresight studies, globalization plays an important role in emerging of foresight generations. Table 1: Elements of Various Foresight Definitions M a rt in ( 1 9 9 5 ) M a rt in & J o h n st o n (1 9 9 9 ) S la u g h te r (1 9 9 5 ) G e o rg h io u (1 9 9 6 ) G e o rg h io u , H a rp e r, K e e n a n , M il e s, & P o p p e r (2 0 0 8 ) B a rr é ( 2 0 0 1 ) M il e s & K e e n a n ( 2 0 0 2 ) M il e s ( 2 0 1 0 ) H a rp e r (2 0 0 3 ) V o ro s ( 2 0 0 5 ) K e e n a n e t a l. ( 2 0 0 7 ) P o p p e r (2 0 0 8 ) P o p p e r ( 2 0 1 1 ) S ch m id t (2 0 1 5 ) C o n w a y ( 2 0 1 5 ) Y ü k se l & Ç if ci & C a k ir (2 0 1 7 ) Systematic studies/process X X X X X X X Looking at medium and long term future X X X X X X Participatory, collective, networking process X X X X X X Building visions X X X X Gathering intelligence X X Learning process X X Mobilized actions X X Joining key agents of change and knowledge sources X X Assessing scientific and technological developments X Looking into science, technology, economy and society X Identifying technologies which have impact to create economic and social benefits, industrial competitiveness, wealth creation and quality of life X 2nd World Conference on Technology, Innovation and Entrepreneurship (WCTIE-2017), V.5-p.224-233 Yuksel,et al. ___________________________________________________________________________________________ DOI: 10.17261/Pressacademia.2017.593 227 PressAcademia Procedia Identifying critical technologies to the success of the country or industry X Cognitive capacity X Setting Priorities X X Changing research system and administrative culture X Identifying and examining weak signals X Activities anticipating, recommending and transforming (ART) technological, economic, environmental, political, social and ethical (TEEPSE) futures. X Actively engaging key stakeholders X Prospective and policy-oriented process X Context for predictive analysis and planning X Promoting trans-disciplinarity research X Underpinning areas of strategic research X Universal Human Capacity X Wiring up the national/regional system of innovation X Strategic Thinking X Common Ownership of Strategies X Incubation of Strategic Approaches X Using organizational, regional, national and international resources X Proper methodology combinations X Identifying technological, economic and social areas to prioritize investments and research X Figure 2: Main Approaches to Foresight Generations 2nd World Conference on Technology, Innovation and Entrepreneurship (WCTIE-2017), V.5-p.224-233 Yuksel,et al. ___________________________________________________________________________________________ DOI: 10.17261/Pressacademia.2017.593 228 PressAcademia Procedia Jemala [29] classifies five foresight generations according to their corresponding three globalization phases by pointing out first foresight studies of related generations according to date: I. First globalization phase: The phase dating back to Christopher Columbus in 1490s and lasting to 1913 with the effect of “Laissez Faire” thought was generalized as Era of Forecast since there were not so many systematic approaches and strategic plans in general. Most of the future studies were being performed just because of inherent human reaction to its fear of undetermined future. II. Second globalization phase: The phase from 1914 to 1980s mainly affected from world wars and information and communication technologies was named as Era of Forecast until 1956 and First Generation of Foresight from 1956 to 1990. First foresight generation focused on science and technology of post war conditions. Although ‘forecasting’ term continued to be used to 1980s, in 1956 China performed forecast having many features of foresight. Systematic manner with participatory methods and strategic planning to be beneficial in societies especially with the efforts of futurology and technology professionals [29], e.g. 30-year technology forecast of Japanese Science and Technology Agency (STA) in 1971, started to be dominant as First Generation of Foresight. III.Third globalization phase: The phase from 1999 to 2009 based on the inequalities between the countries arising from the global trade and finance included all five generations of foresight. Second foresight generation was mainly triggered from industry and markets. It is performed with the participation of different stakeholders and science-technology relation with social-economic development was the main focus. Third foresight generation, approximately in 2000, expands the stakeholders to social actors to create foresight culture and to do studies on different areas like environment, education, ethics etc. apart from just science and technology. Fourth and fifth generations focus on systematic approach with system view more and technology and innovation management become dominant. When it comes to mixed approach –i.e. generations based on certain era and activities- Reger [30] determines three generations based on technology foresight process and assigns certain time intervals per generation [31]: I. First generation (from 1960s to beginning of 1970s): Technology foresight was carried out within organizations and focused on forecasting and prediction. Foresight was conducted as a sub-task of project planning. II. Second generation (from 1970s to beginning of 1990s): Foresight was focusing on technology data and remained a forecasting action. Specialized and separated foresight units were responsible for foresight within organizations. III. Third generation (from 1990s): Technology foresight became an important element of strategic management and decision-making. Not only technologic but also economic, social, environmental and legal trends were taken into account. Activities were extended to encompass networks of organizations. In terms of foresight generations based on activities, Georghiou categorizes generations into five different groups based on the stakeholders involved and activities carried out [32]. Foresight generations are [33]: I. First generation: Merely technology forecasting carried out by experts on the future studies. Main goals are making accurate predictions and expressing results to non-expert audiences. II. Second generation: Foresight activities which began in 1990s in order to combine technology and markets. Industry and academia are bringing together to establish science and business networks. III. Third generation: While keeping technology and markets, social dimension is added to the studies. Industry, academia, government and civil society are the main actors. More stakeholders are involved in evaluation. IV. Fourth generation: Foresight activities are moved away from integrated programs to different actors within science and innovation system. Multiple organizations carry out foresight studies according to their needs with some level of coordination. V. Fifth generation: Structural activities focusing on complex policy issues of global science, technology and innovation systems. The foresight generations in the literature classified based on the certain dates by authors Reger [30] and Jemala [29] (with the addition of the first performing countries) is depicted in the Figure 3. While Reger [30] assorted foresight as three generations up to 2001, Jemala [29] grouped them into five generations until 2009. The generations’ dates were not coherent in their studies because of different arguments used in classification and terminological confusion between forecast and foresight. An individual foresight program can have elements of more than one generation. These generations are not sequential approaches and should be thought as “concurrent, overlapping and reflexive” [34]. 2nd World Conference on Technology, Innovation and Entrepreneurship (WCTIE-2017), V.5-p.224-233 Yuksel,et al. ___________________________________________________________________________________________ DOI: 10.17261/Pressacademia.2017.593 229 PressAcademia Procedia Figure 3: Dates of Foresight Generations in the Literature When foresight generations are evaluated for their methodologies approaches; first generation, which was dominated by forecasting mostly around 1960s, used mostly quantitative methods although some qualitative methods like scenario planning emerge in this generation [35]. For the second generation, in which foresight activities started to increase, participative methods together with qualitative methods became widespread. Third generation, which included social dimension, used the analysis like SWOT (Strengths, Weaknesses, Opportunities, and Threats) more. Fourth and fifth generations, which focus on global science, technology and innovation systems with different actors and complex structures, use mixed and internet based methods more prevalently. Saritas [36] suggests new foresight approach which comprehends complex, inter-dependent, inter-connected nature and behaviors of the foresight system. As sixth foresight generation the assessment of the authors is added to Table 2, which is adapted from Georghiou et al. [19] and [37], and generations are shown with respect to its concentration/dimensions, participating actors, economic rationales and principle. Table 2: Foresight Generations Foresight Generations Concentration Dimensions Participating Actors Economic Rationales Principle First Technology Technology Experts, Professional Futurists Economic Planning To follow the disciplinary taxonomies of science-engineering Second Technology- Markets Academics, Industrial Researchers and Managers Market Failure To provide a bridge between industrial/service sector and economy Third Technology- Markets-Social Dimension More Social Stakeholders (NGOs, Consumer Groups System Failure (socio-economic system) To solve socio- economic problems Fourth Science- Innovation System More Participators of National Policy Exercise Bridging institutions in socio-economic system To build own structures in terms of object of analysis Fifth Global science- technology management- innovation systems More experts, stakeholders and professionals with foresighting skills Bridging institutions in socio-economic system To build own structures in terms of object of analysis Sixth Netocracy 5 , biotechnology, more values and ethics in chaordic social dimension Netocrats 6 , Netizens 7 (crowd-sourced from a much wider range of constituencies than the usual experts), Futurists, Futurizens 8 Blurring the roles of consumers and producers in economy To co-create by combining altogether the desirable visions of stakeholders with evidence from big data 5 "It refers to a perceived global upper-class that bases its power on a technological advantage and networking skills" [44]. 6 "Those who can harness networks of information and master new forms of communication will control finance and legislation, forming the new business and government elites" [45] 7 "People online who actively contribute towards the development of the Net (a Net Citizen)" [46]. 8 "Prescient, future-facing, forward-looking people, citizens of future [47] and futurium (The European Commission Project collecting people's contributions in futures policy constitution) community. 2nd World Conference on Technology, Innovation and Entrepreneurship (WCTIE-2017), V.5-p.224-233 Yuksel,et al. ___________________________________________________________________________________________ DOI: 10.17261/Pressacademia.2017.593 230 PressAcademia Procedia 3.FORESIGHT FRAMEWORKS AND PRINCIPLES The main dimensions of foresight, which are context, scope, artifacts, participating actors and methods, have evolved throughout the foresight journey within its generations until today. So, many scholars have been contemplating about foresight’s theoretical and conceptual framework to catch this dimensional change. It has also brought the need for common vocabulary for foresight thus ontology has become important. “Ontology is a formal, explicit specification of a shared conceptualization” [38] and it provides clarification of knowledge [39]. Within this perspective, in the foresight literature, frameworks play important role to create common terminology. Accordingly, some of well-known foresight frameworks are analyzed in the following paragraphs. Martin [13] analyses foresight as a process having three phases. In the first phase named pre-foresight, the decision taking to perform the process and preparation are the main steps. Second phase is foresight containing comprehensive design, strategic analysis of its possible utilities, consensus about the best promising options, determining the scientific priorities by disseminating the outputs. In the last phase which is post-foresight, implementation of foresight in policy-making and resources allocation take place [39]. Voros [40] defined generic foresight framework by treating it as a process. His framework is based on modification of Horton’s three phased process, combining it with Mintzberg’s strategy view and Slaughter’s strategic foresight approach. While knowledge gathering and strategic intelligence are assessed as inputs; analysis which is related to the question of ‘what seems to be happening?’, interpretation based on the question of ‘what is really happening?’ and prospection related to the ‘what might happen?’ are handled in the foresight phase. Outputs are comprised of strategic choices resulted from broad understanding. By separating outputs and action, he added strategy as a last step that contains actions for decision-making in strategy development and strategy planning. Hines & Bishop [41] viewed foresight as a process requiring six involvements of leaders and organizations defined as framing, scanning, forecasting, visioning, planning and action. Framing contains problem identification and determination of its and its solutions’ expenses. Scanning is the step of being aware of the trends and related information. While forecasting is creating the possible futures, visioning is selection of desired future and determining the position of organization for that future. Planning is generating the road to the desired future and acting is bringing plans to actions on ongoing base. Saritas [36] proposed a Systemic Foresight Methodology (SFM) comprised of Intelligence, Imagination, Integration, Interpretation, Intervention and Impact, all within Interaction, to generate and conduct foresight operations. All of the operations are performed in dynamic, repetitive and evolutionary way and considered in the extent of how systems in the range of foresight are handled. Foresight is implemented with the thought of the internal (e.g. management, processes, motivation, politics, culture, power, skills) and external context (e.g. STEEPV 9 ) in the systemic approach [36]. The systemic approach assesses the foresight with its interrelated and interdependent elements and their complex connections [36]. Within this approach, intelligence phase contains gathering data, analysis of trends and changes to determine the scope and content of the foresight study. Imagination involves creating and interconnecting new ideas, scenarios. Integration is the phase of identifying priorities and creating agreed model of future. While the models and visions are transformed to strategies to be carried out in interpretation phase, plans and policies are required to be constituted in order to put them into practice in intervention phase. The foresight is reviewed and lessons learned are taken to renew it or for better applications in impact analysis. All of the phases in SFM are conducted with the participation of stakeholders in some forms interaction. Schultz [42] took foresight as an integrated process and defined it as a five key activities namely ‘identify and monitor change’, ‘assess and critique impacts’, ‘imagine alternative outcomes’, ‘envision preferred vision’ and ‘plan and implement change’ in order. He puts the change to the center of foresight process and starts with catching the pattern of change with trend analysis. As a second activity, the impacts of change are defined by sorting them according to their relevance and importance. Determining alternative futures and picturing them in the mind is the key element called imagining alternative outcomes. Selecting the desired future and putting it forth as stated vision is the following activity. Last activity is comprised of specifying stakeholders, designating resources for the clear purposes, developing strategies, organizing activities and creating change. With the light of the foresight frameworks in the literature, in this study a generic foresight functional model named ‘FORESIGHT’ which is built to draw outlines of the functional system is developed. When one of the functions doesn’t work properly, it can’t be mentioned about the proper operation of the whole system. In the proposed functional model FORESIGHT, there are nine functional blocks as ‘framing’, ‘obtaining’, ‘reviewing’, ‘establishing’, ‘synthesizing’, ‘illustrating’, ‘guiding’, ‘handling’ and ‘tracking’. In the model, consecutive functions are interrelated and interdependent. 9 STEEPV: Social, Technological, Economic, Ecological, Political, Values analysis tool is a framework to gauge how the external environment will impact a given company’s strategic plan to remain competitive. 2nd World Conference on Technology, Innovation and Entrepreneurship (WCTIE-2017), V.5-p.224-233 Yuksel,et al. ___________________________________________________________________________________________ DOI: 10.17261/Pressacademia.2017.593 231 PressAcademia Procedia Framing: Fulfilling the tasks of determining foresight purpose, scope, content and time horizon. Obtaining: Collecting data and information, gathering participants also by using co-nomination in iterative way which are consistent with its frame stated in the previous function. Reviewing: Sharing ideas and opinions on the accessed data and information related with past and present, summarizing, analyzing them to be processed. Establishing: Thinking about the future with the knowledge created, picturing possibilities in the minds and imagining the alternatives to create futures. Synthesizing: Combining all alternative future thoughts with the present state conditions and resources in an interpretive way. Discussion, negotiation, facilitation and conflict resolution takes place in this function. Illustrating: Pointing out the possible futures, visioning and generating reports, broadcasting with multimedia, sharing in social media. Guiding: Defining actions and changes those will be performed, determining sequencing of them to reach different futures, strategy development and planning. Handling: Taking actions, making changes and solving application problems. Tracking: Evaluating outcomes and results of handling, performing impact analysis to take lessons for learning process. In Table 3, functions in the FORESIGHT have been matched with the phases of mentioned foresight frameworks based on their actions and artifacts within specific phases. Table 3: Foresight Frameworks in the Literature 4.CONCLUSION Future has always been wondered and some systematic studies have been done to get ready to different futures through the time. So, there are different futures studies in the literature including the foresight which is the most common one especially from 1990s. To cover the all elements of prominent foresight definitions in the literature, the new definition of foresight which is based on the resources, methodology and futures strategies is presented. By searching the literature for foresight generations, sixth foresight generation is evaluated as the one dominated with netocracy and biotechnology. It is assessed that the intensive use of big data, Internet of Things, add on biological units and artificial cyborgs will bring ethical and social dimensions together. The sixth generation foresight studies involve the netocrats, netizens, futurists and futurizens as the actors who initiate, carry out the operations and affected from them. Additionally, a generic foresight functional model with nine consecutive phases named FORESIGHT (Framing, Obtaining, Reviewing, Establishing, Synthesizing, Illustrating, Guiding, Handling, Tracking) is suggested with the search of frameworks in the literature. This functional model covers the phases of a generic foresight process regarding to its activities done. Futures will continue to remain the latent area always been tampered by humans even the science allows to read Yüksel&Çifci (2017) Martin (1995) Miles (2002) Voros (2003) Bishop&Hines (2006) Schultz (2006) Sarıtaş (2011) Foresight Functions Foresight Process The Foresight Cycle A Generic Foresight Framework Foresight Key Activities of Integrated Foresight Systemic Foresight F Framing Pre-Foresight Framing O Obtaining Recruitment Identify and monitor change Intelligence R Reviewing Analysis Interpretation Asses and Critique Impacts Imagination E Establishing S Sythesizing I Illustrating Outputs G Guiding H Handling Post-Foresight (Implemantation, Allocation) Action Action T Tracking Renewal Impact Plan and Implement Change Intervention Scanning Forecasting Envision Preferred Futures Integration Interpretation Visioning Planning Pre-Foresight (Decision, Preparation) Inputs Foresight (Process Design, Strategic Analysis, Agreeing, Disseminating) Generation Prospection Strategy 2nd World Conference on Technology, Innovation and Entrepreneurship (WCTIE-2017), V.5-p.224-233 Yuksel,et al. ___________________________________________________________________________________________ DOI: 10.17261/Pressacademia.2017.593 232 PressAcademia Procedia the thoughts and determine the people tendencies in the future. 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Lee, “Futurists and futurizens,” no. July. pp. 1–3, 2013. work_ax273z7ldzbrplmak5eznfsbr4 ---- Antiquity - V O L . X L V I N o . 181 XTARCH 1972 Editorial The Guy Tourguide map that was given us when we hired a car to drive from New York to Boston last September had a special section: Tourguide Facts : Places of Interest and, under New Hampshire, was this entry: N . Salem. Mystery Hi21 Internationally famous archaeological mystery And then we remembered correspondence between Frank Glynn and Tom Lethbridge in the thirties and photographs passed on to us of what purported to be pre-Columbian mega- lithic monuments in New England. We drove to Mystery Hill so soon as we decently could leave the better-known famous archaeologists of Harvard. It lies some 65 km. north of Boston and is 40 km. from the sea. As we nervously approached it, we saw a great notice saying ‘Welcome to Mystery Hill-the American Stonehenge’, and on arrival were presented with a pamphlet describing it thus: IZ-acre settlement of megalithic structures, huts, dolmens, carefully built walls, intricate underground drainage systems, carvings, rock- basins and bowls : several underground caverns. Centered by a grooved slab, with supporting table, called the sacrificial stone. The tea and souvenir shop which issued tickets for admission, and which we approached with mounting trepidation, had notice boards with cuttings from various journals. One by Dorothy Patten, in the Haverhill Gazette for 3 I July 1967, described Mystery Hill as: . . . the largest unsolved complex of man-made stone structures ever found in the United States . . . How far back in the centuries do these date? What are they and who built them? Are they the products of the Bronze Age? The Phoenicians ? Irish Culdee Monks ? Vikings ? Indians ? Or the eccentricities of Colonial farmer Jonathan Pattee who occupied the site from 1826-1848 ? We went round the site with interest and spent another whole day there with Paul Johnstone of BBC Chronicle, who was making a film of this strange complex of buildings. Pattee’s Hill is 800 m. high and the stone complex covers three quarters of an acre (0.30 ha.) on the top of the hill. At first sight it looks like a cross between a large neglected rockery, disused farm out-buildings, and the ruins of a folly, all with ghost memories of Cornish fogous, Grimspound, French souter- rains, and Sardinian cappane. In our judgement it certainly bears no morphological or construc- tional resemblance to the great megalithic monuments of prehistoric Western Europe, apart from, of course, the coincidental resemb- lances that occur when dry stone walling is used in a building for construction and large stone slabs for trabeate roofing. The pigsties of Pembrokeshire and the clapper bridges of Dartmoor are as much ‘megaliths’ in the proper archaeological sense of the word, as are some of the odd buildings at Mystery Hill. The site has been known to natives of the area for more than a hundred years as Pattee’s Caves. Jonathan Pattee was a French Huguenot farmer who lived there for a while. In 1936 the site was bought by a prosperous gentleman, a retired insurance executive, from Hartford, Connecticut, named William B. Goodwin. He brought the site to the attention of archaeologists and himself dug large portions of it, with, apparently, little care or attention. He decided, on the results of his diggings, that it was a settlement of Irish Culdee monks. I A N T I Q U I T Y In 1939 Goodwin persuaded Dr Hugh Hencken of Harvard to visit the site. Hencken was unable to agree that the site was,of Irish origin, and thought it colonial: he published his views in an article entitled ‘The “Irish Monastery” at North Salem, New Hampshire’ in the New England Quarterly, XII, September 1939. His learning and argument however did not convince Goodwin who believed the site an Irish monastery until his death in 1950; and, in 1946, published a book entitled The Ruins of Great Ireland in New England. In 1955 the Early Sites Foundation of New England authorized and financed an expedition to dig the site: the excavators were Junius Bird of the American Museum of Natural History and Gary Viscelius of Yale. After six weeks’ digging the Bird-Viscelius expedition decided that there was nothing earlier than revolutionary days and Jonathan Pattee. One member of the expedition, Frank Glynn of Clinton, Connecticut, and sub- sequently President of the Connecticut Archaeo- logical Society, did not agree with these find- ings and continued to excavate on his own for many years. Glynn alleged that he could point to forty-eight similarities between Mystery Hill and the Bronze Age of the Old World: he believed the site to be the most westerly exten- sion of the European megalith builders, and he dated the site to between 3000 and 500 BC. The site is now owned by Robert Stone of Derry, an engineer with Western Electric, and President of the New England Antiquities Research Association (founded in 1964). New excavations have been proceeding at Mystery Hill for the last six years under the direction of James P. Whittall Jr: Stone and Whittall are convinced that they are dealing with something much earlier than Pattee, and, while they agree that such evidence does not date the site, were very excited by the C14 dating of charcoal found between walling stones of one of the buildings. This gave a date of 3475 f 210 BP or I525 BC: the dating was determined in the Geochron Laboratories at Cambridge, Mass. (reference GX.23 10). This date shows that the site had an early occupation; but we share Hencken’s views that the visible structures of the present day are unlikely to be earlier than the 17th century. A colleague summed up his views recently by saying that it was a classic example of ‘how archaeology is used to take the great American public for the proverbial ride’ and how right he was! The real interest of Mystery Hill is not that it is a great archaeological mystery, but that it is built up as such. The great American public want mystery and they passionately want proof of the settlement of their country in pre- Columbian times. The bookstall at Mystery Hill sold copies of NEARA-the quarterly Newsletter of the New England Antiquities Research Association; and C. M. Boland‘s They all discovered America. We devoured Boland avidly. His book, des- cribed as ‘an absorbing, imaginative account of the explorers who came to America before Columbus’, was first published in 1961, and is now a paperback to be found everywhere. When Boland’s book first came out the Sun Francisco News-Call Bulletin said ‘Americans should read this book to learn just how long their native land has been there’, and the Indianapolis Star declared that ‘If Christopher Columbus had known half as much about the discovery of America as the author of this book, he never would have taken the trouble.’ Boland has nineteen pre-Columbus discoverers of America : these include Phoenicians, Romans, the Chinese Hoei-shin (and where indeed did he get to?), St Brendan, Irish Culdee monks, Vikings from Bjarni Herjulfsson to Bishop Eric Gnupsson, Quetzalcoatl, Prince Madoc, Paul Knutson, Prince Henry and the brothers Zeno, and Joaz Vaz Cortereal. Every con- ceivable dubious find or known forgery is dragged into service by Boland, from alleged Phoenician inscriptions through the Dighton Rock on Assonet Neck, Rhode Island, the Minnesota Stone, the Newport Tower (of course) and the Beardmore finds of 1931. There is a photograph of a carving of an alleged Phoenician ship revealed when the waters of Lake Assawompsett in Massachusetts were lowered, and of Mr Albert Wheeler holding aloft a fragment of a suspected (by whom and why?) Viking ship found on his property in Massachusetts. And as he finished writing this 2 E D I T O R I A L amazing collection of credibilities and nonsense, Boland was able to trumpet abroad the announcement of the authentication of a Roman head of the 2nd century AD found in Calixtlahuaca in Mexico ‘under three sealed and undisturbed floors, found in 1940, but an- nounced by Dr Heine-Geldern in the Inter- national Congress of Americanists in Vienna in July 1960’. Boland coins a useful and amusing phrase: ‘the NEBC principle’, which means the model of thought that insisted there could be no Europeans in America before Columbus, and this model of thought is to be recorded and described in the same way as we are describing, from Boland and Gordon and others, the reverse model which we may encapsulate in a similarly useful and perhaps amusing phrase : ‘the MEBC principle’, which means many Europeans (and Mediterraneans and Orientals and others) in America before Columbus. The N E A U newsletters are, unhappily, the same sort of MEBC stuff that one reads in Boland: they are full of oddities, quiddities and lunacies; they are credulous and querulous. Here are men trying hard-oh, so hard and often so honestly-to invent a past, but who often remain unconvinced of their own myth. All the current lunacies are ventilated in the NEARA newsletters, the Landsverk-Monge theory of ciphers and dates hidden in runic inscriptions, balancing rocks, astronomical alignments, bogus ‘dolmens’ at Martha’s Vine- yard, Madoc’s stone forts in southern Illinois, the Parafba Stone, the Newport Tower, the Dighton Rock, the Roman (?) inscriptions in Maine, and the second-century AD Hebrew and Roman coins from Kentucky. We returned to Cambridge, Mass., dejected and disappointed by this sortie into the maverick archaeology of New England. As we had left the little museum-cum-cafb-cum- souvenir shop, the headline of an article in the Lawrence Eagle-Tribune for LI June 1965 caught our eye: ‘Antiquity Researchers Probe Secrets of Mystery Hill’, but it gave us no comfort. A shelf in the Harvard Coop dis- played five books, four of them new, discussing in various ways the problems of pre-Columbian America. I. Collectors’ luck : giant steps into prehistory by Betty Bugbee Cusack. Stonehaven, Mass. : the G.R. Barnstead Printing Company, 1968. $5. 2 . Before Columbus by Cyrus H. Gordon: N e w York : Crown Publishers, 1971. $15. 3 . The Quest f o r America (ed. Geoffrey Ashe). New York : Praeger, I g 7 I . $15. 4 . M a n across the sea : problems of @re-Columbian contacts (edited by Carroll L. Riley, J . Charles Kelley, Campbell W. Pennington and Robert L. Rands). Austin and London: University of Texas Press, I 9 71. $12.50. 5 . The European discovery of America : vol. I : The northern voyages A D 500 to 1600 by Samuel Eliot Morison. London : Oxford University Press, 1971. A7.00. The last three books are of great importance and will receive special and serious considera- tion in a future number of this journal. The Bugbee Cusack and Cyrus Gordon books are autre chose, and must be summarily dismissed here. Mrs Bugbee Cusack’s book is a scissors-and- paste affair of cuttings about prehistory in America that have interested her. It begins with a photograph of a piece of metamorphic rock 300 to 400 million years old, found by the author at Cape Cod in 1966, and ends with a photocopy of her husband’s deposit of $ 5 0 with Thomas Cook and Son ‘for trip to Moon if and when trip is feasible: refundable on request’ and dated 11 July 1961. In between these unusual items we are treated to all sorts of curious things from Irish monks, Vikings and Mystery Hill to an account of how herring gulls navigate in fog, runic (??) inscriptions from Maine and Massachusetts, and a delicious titbit, namely that in 1695 the town of Sandwich (which, incidentally, has in addition to its reputation for glass, the lovely spire on its Congregational Church designed by Christo- pher Wren), passed an order that ‘every unmarried man in the Township yearly should kill six blackbirds, or three crows, while he remained single, and then should not marry until he obeyed and fulfilled that order to the letter’. Mrs Bugbee Cusack is frivolous and futile: she is, encapsulated in a book, the uninformed 3 A N T I Q U I T Y conversation one hears in the cocktail hour either side of the Atlantic. She was not expect- ing t o be taken seriously, and we respect her expectations: hers is a jeu d’esprit of enthusiasm and lunacy. Not so Cyrus H. Gordon who is a professional scholar and teacher, Head of the Department of Mediterranean Studies at Brandeis University in Boston. T h e publishers’ blurb describes him as ‘an internationally respected scholar . . . the author of some thirteen books’ and his book as ‘a revolutionary treatise by one of the world’s most eminent scholars’. Robert Graves, the distinguished poet, who, even in the moments when he feels most inspired by his imaginary White Goddess, could hardly be called a person knowledgeable about the ancient history of western Europe and pre-Columbian contacts with America, writes: ‘Romantic novelists and amateur historians have so often tried to sell us news of pre- Columbian traffic across the Atlantic, long before the days of Leif Ericsson, that when at last it comes, irrefutably substantiated and dated by one of the world’s most dependable scholars, the shock makes us gasp. Professor Gordon is the newsbringer.’ Turning eagerly to Before Columbus, knowing Gordon’s reputation, and rather warily brush- ing aside publishers’ blurb and Graves’s extra- vaganza, we read the book. What is it? Just a load of concentrated and dangerous rubbish. What has happened to Professor Gordon? He believes that the portraits illustrated and des- cribed by Alexander von Wuthenau (see Antiquity, 1971, 229) are of European and African and Asiatic types (but what does he, a Semitic scholar, mean by referring to a Semitic type ? H e must know better than most of us that Semitic is a linguistic and ethnic, not racial, term); and he alleges that the Greeks knew America. ‘To sum up,’ he says (p. 49), ‘Greek classics independently and repeatedly attest transatlantic contacts between the Mediter- ranean and America.’ H e suggests that ‘we visualize the founders of ancient astronomy as setting up bases in the Near East, Middle America and the West Pacific’ (p, 172). He sees ‘the megalithic monuments of the Bronze Age mariners’ as ‘tangible reminders of a world civilization, with highly developed science and technologies’. H e believes in the Paraiba inscription, the Metcalf stone, the Bat Creek Hebrew Inscription, the Roman Head from Calixtlahuaca, the 2nd century AD Hebrew and Roman coins from Louisville, Clay City and Hopkinsville, and thinks that Mexico ‘rich in silver and other metal ores is a possible identi- fication for Tarshish‘. This is not the lunatic fringe of archaeology: this is not the world of the New Diffusionists, Black Horses, Atlantis, Pyramidiots, straight- trackers and the rest of them, the world which every student of antiquity recognizes, with an embarrassed smile, as a danger only to those whose weak and muddled heads prefer the comforts of unreason to the difficult facts of archaeology. This is dangerous stuff because it is set out as scholarship by a professional scholar. This is poisoned chocolate : attractive from the outside, decked out in good wrappings -but, beware : the filling is bitter-sweet, this is false-centre archaeology. T h e fantastic Before Columbus must, alas, be placed on one’s shelves alongside Elliot Smith, Perry and Raglan. I t contains sentences very reminiscent of the hyper-diffusionists, such as, ‘If high independently invented civilizations have existed, they were not on this planet’ (p. 35). We are reminded of what SamueI Johnson said of Monboddo: I t is a pity to see Lord Monboddo publish such notions as he has done: a man of sense and so much elegant learning. There would be little in a fool doing it; we should only laugh; but when a wise man does it we are sorry. Other people have strange notions, but they conceal them. If they have tails, they hide them: Lord Monboddo is as jealous of his tail as a squirrel. T h e Paraiba inscription is Gordon’s tail and he dedicates his book to Jules Piccus, now a Professor of Hispanic Studies at the University of Massachusetts at Amherst, who told Gordon that he had acquired a scrapbook ‘for a small sum at a rummage sale in Providence, R.I.’: this scrapbook contained a new copy of the text of the inscription found by slaves of Joaquim Alves da Costa, on 11 September 1872, on his plantation at Pouso Alto near Parafba in Brazil. 4 E D I T O R I A L Ernest Renan, at the time the leading authority on Canaanite epigraphy, but whom Gordon castigates as a person ‘whose knowledge and reputation were exceeded only by his pedantry’, declared the inscription to be a fake. Gordon believes it to be true and provides a fresh translation from the text in the scrapbook (the original stone having vanished), and finds that it records a crossing from Canaan to Brazil in 534-531 BC. It is this translation, his conviction of the authenticity of the stone, and its general implications, if authentic, that started Gordon off on writing this unhappy book. Unhappy because it is frankly and out- rageously partisan. The possibility of trans- atlantic voyages in pre-Viking and pre- Brendan times is denied these days only by a few. It is the archaeological or other proof that such voyages did indeed take place that interests us all. What evidence there is needs careful weighing: every alleged find from Paraiba to Bat Creek studied with care and both sides of each argument fairly presented. This is what Gordon does not do. He says, ‘If I have learned anything throughout nearly half a century of study it is to keep an open mind and to avoid confusing majority opinion with truth‘ (p. 79). What an admirable sentiment, but what a pity that Gordon should now have closed his mind so that he confuses minority opinion with truth. We are reminded of Elliot Smith‘s phrase in his 1928 Huxley Memorial Lecture: ‘The set attitude of mind of a scholar may become almost indistinguishable from a delusion.’ Once after a lecture in California we were asked by an anxiously interested lady, a kind of Mrs Betty Bugbee Cusack, why scholars like Lowie and Dixon and Wauchope would have no truck with Egyptians and lost tribes in America, nothing to do with Atlantis and Mu. ‘Can’t we believe what we read in books?’ she cried in despair (and with what joy she will seize on Before Columbus). Perhaps her best answer is contained in two sentences on page 38 of Gordon’s book: ‘Ignorance is a curable disease’, and ‘Not everything written as history is true.’ a The death of T. C. Lethbridge in the early autumn of last year took away from us a man who had been a colourful, stimulating, provoca- tive and often controversial figure in British archaeology; a man who could very properly be described, in Cyrus Gordon’s phrase, as one who throughout his life kept an open mind and avoided confusing majority opinion with truth. Tom Lethbridge was one of the last of that invaluable band of dilettante scholars and skilled devoted amateurs of whom we have had so many in Britain. The long list begins, if we exclude the antiquaries of the 17th and 18th centuries, with men such as John Frere and William Pengelly, and continues through Lubbock, Greenwell, Pitt-Rivers, Williams Freeman, Alexander Keiller, the Cunvens and many another to the present day-indeed the present day represented by two of the Trustees of ANTIQUITY: Elsie Clifford and I. D. Margary. Perhaps, for a short while, Tom Lethbridge was a semi-professional: he taught Anglo-Saxon archaeology in Cambridge for many years and was Honorary Curator of Anglo-Saxon anti- quities in the Cambridge Museum of Archaeo- logy and Ethnology. But even so, during those years one never thought of him as a member of the establishment : he stood outside, viewing scholars and crackpots with the same critical detachment and amusement, to the benefit of both and the advancement of archaeological scholarship. Much of his writing had a fresh- ness and an eager restless sense of enquiry: we particularly remember Boats and boatmen (1952), Coastwise craft (1952) and Herdsmen and hermits: Celtic seafarers in the Northern Seas (1950), this last book described by Sam Morison as ‘a chatty book by an imaginative archaeologist’. That was the essence of Tom Lethbridge : he was an imaginative archaeologist. Sometimes, not unnaturally, as with the discoveries of hill figures he was convinced he had made on the Gog Magog Hills near Cambridge, it seemed to many that he was too imaginative. Others warmly supported him. The Wandlebury figures or non-figures are unimportant in an assessment of Lethbridge’s work: he showed us all that without informed imagination, the interpretation of archaeology could be deadly dull. This is perhaps why he and Cyril Fox were such close friends from 5 A N T I Q U I T Y their Cambridge days together in the twenties : both wanted to make the past of man alive. The generation of young men and women who came under Lethbridge’s influence at Cambridge in the twenties and thirties will never forget his enthusiastic reconnaissances and excavations, and his stimulating, wide-ranging and mind-blowing conversation, both in the field at picnics (the while D r Palmer was experimenting dangerously with his home-made mixture of cyder and beer which invariably broke the bottles into which this lethal mixture was put, or D r Lucas was announcing that all the manifestations in the fens were due to ‘the great wind of the Resurrection’), or at those gargantuan high teas (four fried eggs and six rashers of bacon as the first course) at his house outside Cambridge curiously enough, as we now recall, named Mount Blow. Certainly the writer of these words will not forget. Professor Christopher Hawkes, who knew Lethbridge well, wrote appreciatively of his work in The Times for 6 October 1971 and The Times and Professor Hawkes have allowed us to quote the following sentences: T o your notice of Tom Lethbridge, I should like to add two essentials: the strength and honesty of his character as a man, and the singleness of purpose that united all his work, as experimental testing of what he found by observation. He liked to respect the workof others; yet he preferred to test that too. . . . His well- observed drawings had their part in all he wrote; and his exploring of ancient dwellings, such as the ‘wheel house’ at Kilpheder and round Cambridge of Anglo-Saxon and earlier graves and cemeteries, not only assembled facts in an array for which research will long be grateful, but made them reveal the lives that people had lived. His archaeology stretched back into the past directly from the present, from the people and the places he knew familiarly: it could start ‘from your empty cartridge left smoking on the ground’. T h e present writer well remembers the effect that Lethbridge had on him. Coming from an intensive academic sixth-form education to the Cambridge Tripos in Archaeology and Anthro- pology, he found the study of man’s past academic and very learned: it was full of artifacts and taxonomy, of typology and cross-dating. T h e tub was there but Diogenes was missing. Lethbridge showed us Diogenes and brought ordinary man and the ordinary everyday doings of farmers and sailors into what had sometimes seemed from Montelius onwards as no more than a study of tool types and houseplans. H e was a practical, sensible, down-to-earth country- man. H e would have appreciated the following passage from Sam Morison’s book, to which we have already referred: Modern sailors are so dependent on the mariner’s compass that they find it difficult to imagine how any ship could find her destination across a broad ocean without one. But the Polynesians did so in a wider ocean than the Atlantic and simple seafaring folk to this day do it. Fishermen used to sail from Newfoundland to Labrador without a compass. And as a sojourner on the rocky coast of Maine, I have heard a lobsterman say ‘I don’t need no compass to find my gang 0’ traps in a fog, or to git home, neither.’ Ensel Davis, a mariner and lobster fisherman of Otter Creek, Maine, who died recently at a great age, was asked how he found his way home through fog without a compass. ‘By the ocean swells’ he said, ‘they always run south to north.’ ‘But supposing there is no swell?’ ‘There always is one, even in the calmest day, if you know how to look for it.’ Lethbridge, like Cyril Fox, took us out from our studies and museum cases, to see how life was lived in Fenland farms, in Scottish crofts, and by fishermen and sailors everywhere. They have gone, but the breath of fresh country and sea air they blew through academic archaeology, remains. a And speaking of fresh sea air and swells, these words are being hammered out on the Purser’s typewriter aboard the t.s. Bremen (mark V, formerly the French Pusteur, and now making her last transatlantic crossing, at least under the North German Lloyd flag) in mid- Atlantic in mid-December in conditions des- cribed on the ship’s notice board as sehr hohe see and phenomenal. Looking out to sea from the comparative comfort of the bar, a glass of Steinhager (as privately prescribed in his 6 wisdom by the President of the Prehistoric Society) clutched firmly in our hands, observing the sixty-foot waves outside, and the passengers, glasses and ship’s unanchored furniture within sliding from side to side with the confused regularity of the motions of the high seas, one is filled again with wonder, delight and admiration for those who, long before the compass and stabilizers, crossed the Atlantic in pre-Colum- bian days. We lift our glass to S t Brendan, and keep a look out for friendly whales. How nice it would be to meet some modern Jasconius! Readers will be interested in the dates of two exhibitions of special importance which will be mounted in London this year. T h e first is the exhibition of fifty of the finest pieces of Tutankhamun’s treasure : this will open in the British Museum on 29 March and will be there for six months; Sir John Wolfenden, Director of the Museum, has declared that this is the most splendid exhibition the Museum has ever staged. T h e treasures are so valuable that they are not being insured: they will be covered by an indemnity for ‘many million of pounds’ by the British Government. This exhibition com- memorates the fiftieth anniversary of the discovery of the treasure by Howard Carter and Lord Carnarvon in 1922. T h e second exhibition is called Chaucer’s London: The Mirror of all England and will be mounted in the London Museum from I April to 31 August (weekdays 10 to 6, Sundays 2 to 6). I t will contain a rare wealth of medieval material assembled from all over the British Isles. Among those contributing to the exhibition are the Guildhall Museum, the British Museum, the Victoria and Albert Museum, the Public Record Office, Westmin- ster Abbey, the Glasgow City Museum, the Liverpool Museum, Exeter University Library, Winchester College, S t Albans Abbey, and many private collectors. 6 D r Elisabeth Munksgaard, of the National Museum, Copenhagen, writes in a letter dated 16 June 1971: Inspired by the satirical masterpiece mentioned in the June 1971 issue of ANTIQUITY I should very much like to draw your attention (and that E D I T O R I A L 7 of the readers, too) to the most amusing archaeo- logical satire I have ever had the privilege to read. I refer to the German publication by Hans Traxler, Die Wahrheit iiber Hansel und Guetel. Die Dokumentation des Marchen der Briider Grimm. Eine glaubwiirdige Parodie (Bar- meier & Nikel, Frankfurt/Main, 1963; pocket edition by Heyne Verlag, Munich, 1967). This excellent book is not only very wicked; it is also uproariously funny. I shall not go through the contents in detail thus spoiling the mirth of future readers-but only mention the hilarious idea of an amateur archaeologist setting out to find and excavate the witch’s house (taking the contents of the fairy tale as gospel truth). T h e satire and wickedness is very subtle throughout as the description of reasoning and conclusions, C14 tests, dendrochronology, chemi- cal analyses, and anthropological determinations comes so near to sober truth that it sends cold shivers down one’s spine. An awful warning to us all and a very clever lesson in curbing too vivid imaginations. There is only one drawback concerning this nasty masterpiece (which is also amply illustrated with the most gorgeous photographs)-it is out of print. May this letter inspire the publishers to issue a new edition! This exquisite publication has done much to restore one’s faith in the German nation which has always been justly stigmatized as having no sense of humour whatsoever. But Mr Traxler has certainly done more for his country than a host of politicians could ever hope to attain. If any reader of ANTIQUITY should know of other archaeological satires, maybe the editor would undertake to publish the titles to enlighten all of us who can’t resist ‘The lighter side of archaeology’ (cf. Antiquity, XI, 1937, 80 ff.). How about a column headlined, ‘Though this be method, yet there is madness in it’? (May the great poet forgive me!) a Finally an apology to author and reviewer o f I vetri romani del Museo di Aquileia (Pubblica- zioni dell’ Associazione Nazionale per Aquileia) : M. C. Calvi and D r D. B. Harden. The correct title is as above and needs amending in our December 1971 issue p. 307 and in Contents and Index of the same number. P. 307, 1. 47, col. 2, for grazed read grozed and p. 308, 1. 2, col. I for Clavi read Calvi. We are sorry about these careless errors : transatlantic editing and production has its problems! work_azq3locmqbaidcnikrsvafr3qm ---- 11 July 1970 Leading Articles DIBxn=U 59 and in the level of blood urea, while the salt-retaining effects may aggravate the oedema and lead to hypertension. In a recent controlled trial9 of steroid treatment versus sympto- matic treatment alone the early mortality was higher among the patients who received steroids, emphasizing that even the modest doses of steroids given were potentially dangerous. It may be argued that doses of about 20 mg. prednisolone daily serve only to suppress adrenal function and that doses of 60 mg. daily for several months are necessary to produce an effect on the renal disease. Such regimens are correspondingly more dangerous, and no controlled trial has been published that investigates their value. There is some evidence10 that the administration of a double dose of steroids on alternate days is less toxic but as efficacious, and it is reasonable to give large doses in this way. Recently M. Friedman and L. B. Strang"' have shown that corticotrophin (A.C.T.H.) produces less stunting of growth for a given effect than does prednisolone. However, the problems of hypertension and a cushingoid appearance remain. Owing to the limitations of steroid therapy interest has grown in the cytotoxic drugs. Azathioprine,12 cyclophospha- mide,13 14 and chlorambucill5 have all been used extensively, and there can be no doubt that cyclophosphamide and chlorambucil are helpful in the treatment of the patient with a minimal renal lesion. The value of azathioprine is less certain. M. Abramowicz and his colleagues"6 concluded that, at least in children and in fairly low dosage, it was no better than a placebo. Remissions induced with cyclophosphamide last longer than those induced with steroids,17 18 and many patients who were previously dependent on steroids now appear to have been cured and to require no further treatment. There is some doubt about the best therapeutic regimen. M. W. Moncrieff and his colleagues'4 have induced a leucopenia (and usually alopecia) with a high initial dose and then maintained the leucopenia for about three months with a relatively small dose. On the other hand, J. F. Soothill"7 18 has found that the continuous administration of an inter- mediate dose for two months produces a remission without inducing either leucopenia or alopecia. Relapse occasionally follows withdrawal of treatment, and in some cases it is related to inadequate therapy.'4 Given to patients with proliferative glomerulonephritis, azathioprine has occasionally produced a dramatic response.'2 Relatively high and dangerous doses (4-6 mg./kg. body wt. per day) have been necessary, and recently there have been attempts to use smaller doses combined with modest doses of steroids. A small controlled trial'9 of this method of treatment in adults showed slight benefit that was just significant statistically, and a much larger trial at present in progress under the supervision of the Medical Research Council has led to the same conclusion. There have been no controlled trials of cyclophosphamide in the treatment of proliferative glomerulonephritis, though occasional patients, especially children, do seem to respond. Patients with membranous nephropathy run a downhill course over many years. During this time their proteinuria fluctuates and occasionally their urine becomes free of protein for a period. The underlying lesion persists, however, and it is generally considered that neither steroids nor cytotoxic drugs affect the course of the disease.20 Occasional reports2' 22 challenge this view, and recently S. P. Rastogi and colleagues22 reported on four patients who were given prolonged courses of steroids and lost their proteinuria for periods up to 6 5 years. Repeated renal biopsies showed that the histological lesion persisted but had not progressed significantly. Pericarditis and Rheumatoid Arthritis Patients with systemic lupus erythematosus may present with rheumatoid arthritis, and patients with unequivocal rheuma- toid disease may develop the serological changes of systemic lupus erythematosus. But the great majority of patients show the lesions of only one of these diseases, and the frequency of their overlap has been exaggerated. It is therefore surprising that little attention has been paid to the pericarditis of rheumatoid arthritis when it is so well recognized as a feature of systemic lupus erythematosus. Necropsy studies have given an overall incidence of peri- carditis in association with rheumatoid arthritis as high as 30%1-3 and this complication is recognized in about 7% of cases of juvenile rheumatoid arthritis.4 A recent study by J. Kirk and J. Cosh of 33 patients with rheumatoid peri- carditis is therefore of interest.5 The condition must be taken seriously, for acute or chronic pericardial effusion, chronic constriction, and even haemopericardium with tamponade may supervene. The pathological changes found in most cases at necropsy are obliterative pericarditis, with acute fibrinous pericarditis making up almost all the remainder. Specific granulomatous infiltration is rare; when it is present the lesions are found on the epicardial surface of the heart as small necrotic nodules similar histologically to the sub- cutaneous rheumatoid nodule.2 3 The onset of pericarditis seems to bear no relationship to the duration of the arthritis, though it is particularly apt to be found in middle-aged males in whom the arthritis was of acute onset. It is perhaps commoner when the arthritis is active than when it is dormant. Serological tests for rheuma- toid arthritis are usually positive in patients developing peri- carditis, and one-third of these patients have typical rheuma- toid nodules. Anaemia and a raised erythrocyte sedimentation rate merely reflect the activity of the arthritis. On careful inquiry a history of chest pain can be obtained in about half the patients with pericarditis. The pain is fre- quently pleuritic and fleeting in nature, lasting only a matter of hours or a day or so. In some the pain may closely simulate that of cardiac ischaemia, but it is distinguished by alteration in intensity with.changes in posture. The remaining half of these patients have no symptoms, and the condition is diagnosed on routine clinical examination. The characteristic auscultatory finding of a pericardial friction rub may be absent, but it is heard in most patients at some period of their illness. The rub may be atypical and may be confined to systole, making differentiation from a systolic murmur difficult. This difficulty may be increased by the persistence of the rub unchanged for several months. Low- grade fever is frequently present and should alert the physician to seek this particular complication. Confirmation may come from electrocardiographic changes, alteration of the cardiac outline on chest radiograph, or aspiration of pericardial fluid. The characteristic E.C.G. pattern in pericarditis is the raising of the ST segment without T wave inversion. Later, abnormalities of the T waves may appear, including inversion; they are found only when the 1 Bywaters, E. G. L., British Heart_Journal, 1950, 12, 101. 2 Goehrs, H. R., Baggenstoss, A. H., and Slocumb, C. H., Arthritis and Rheumatism, 1960, 3, 298. 3 Lebowitz, W. B., Annals of Internal Medicine, 1963, 58, 102. 4 Leitman, P. S., and Bywaters, E. G. L., Pediatrics, 1963, 32, 855. 5 Kirk, J., and Cosh, J., Quarterly Journal of Medicine, 1969, 152, 397. ' Hart, F., British Medical_Journal, 1966, 2, 131. 7 Harrold, B. P., British Medical Journal, 1968, 1, 290. o n 5 A p ril 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://w w w .b m j.co m / B r M e d J: first p u b lish e d a s 1 0 .1 1 3 6 /b m j.3 .5 7 1 4 .5 9 o n 1 1 Ju ly 1 9 7 0 . D o w n lo a d e d fro m http://www.bmj.com/ 60 1 1 July 1970 Leading Articles REDICAL JOURNAL pericarditis is active. Sometimes the pericarditis is present without any E.C.G. changes.5 About half the patients reported on by Kirk and Cosh also had rheumatoid lung or pleural lesions.5 Pleural effusion is common, but pericardial effusion is rare. In the few cases in which pericardial effusion occurs the fluid closely resembles the straw-coloured non-viscous fluid found in the pleural cavity; typically it is high in protein but low in sugar. L.E. cells are found in the blood in a minority of patients,6 but even then the diagnosis of rheumatoid arthritis as opposed to systemic lupus erythematosus is usually clear. To assess the incidence of rheumatoid pericarditis Kirk and Cosh made a prospective study of 100 inpatients with severe rheumatoid arthritis selected at random. They found it was 10%. But their patients had sufficiently severe disease to warrant admission to hospital, and so high an incidence would not be expected in patients outside hospital. The prognosis of rheumatoid pericarditis is generally good. The condition appears to run a benign course, usually with rapid spontaneous resolution. Specific therapy does not prevent its onset or shorten its course once established. If pericardial effusion occurs, early aspiration is advised to prevent tamponade and to reduce the risk of later pericardial constriction. B. P. Harrold7 reviewed 17 reported patients with rheumatoid pericarditis who had undergone pericardi- ectomy for constriction and noted that in only three did the interval between onset of arthritis and operation exceed five years. This suggests that if constriction is going to occur it is unlikely to do so in patients with arthritis of long duration. Rarely, heart failure may be the presenting symptom of rheumatoid pericarditis, and the onset of oedema in a patient with rheumatoid arthritis should prompt the doctor to consider this possibility. Children's Eyes Errors of refraction are almost universal, and few of us attain old age without recourse to spectacles. Yet, though the refractive state of the eye is simply the product of physical variations in the eye's anatomy which admit an exact measurement, our knowledge of these measurements in sub- stantial numbers of the population at different ages has been very incomplete. A recent comprehensive report by Arnold Sorsby and G. A. Leary' is welcome not only because of the information it provides on the patterns of refractive changes in growing children but also because it helps to clear away some of the myths that are still being reported about the prophylaxis and "treatment" of short-sightedness. The infant's eye is normally hypermetropic (long-sighted), and as the eyeball grows in length the hypermetropia decreases. The eye thus becomes more normal-sighted or even short- sighted until growth comes to an end by the age of 14. Between the ages of 3 and 14 the eye becomes about 1*2 mm. larger. But some 60% of the potential decrease in hyper- metropia (or increase in myopia) that this elongation could be expected to produce is eliminated by a simultaneous reduction in the converging power of the cornea and lens, so Sorsby, A., and Leary, G. A., Medical Research Council. Special Report Series, 1970, No. 309. 2 Sorsby, A., Sheridan, M., and Leary, G. A., Medical Research Council. Special Report Series, 1962, No. 303. 3 Morgan, O., British Medical_Journal, 1970, 1, 175. 4 Gilkes, M. J., British MedicalJournal, 1970, 1, 758. that the resultant change in refraction is little more than 1 dioptre. And, as most infants are more than 1 dioptre hyper- metropic, only exceptionally does this trend produce a frank myopia, and that of quite a low order. In about 28% of children a greater elongation of the eyeball during this growth period does cause a further shift towards myopia than can be compensated for by a slight additional decrease of the power of the cornea and lens. The change in cornea and lens is in part the direct sequel to this elongation and would itself tend to neutralize some of this adventitious myopia. The authors of the report found that bodily heights and weights were unrelated to the refraction at the beginning and end of the period ofobservation, and there were no obvious sex differences in these developments. As the authors had shown in an earlier report,2 the refraction and its components are genetically determined. And this, they state, must be assumed to apply also to the anomalous axial elongation and paradoxical changes in the cornea and lens. The provision of correct spectacles will thus have no influence on this predetermined refractive change3 4 any more than on other organic disorders of the eyeball. Caribbean Food and Nutrition Institute Christopher Columbus made his first landfall in the Caribbean in October 1492 at an island in the Bahamas which he piously named San Salvador. Believing he had reached Asia, he imposed on posterity the confusing practice of calling the people of the New World "Indians" and the Caribbean islands the "West Indies." The area was at that time inhabited by the gentle Arawaks and the fierce Caribs, who gave us the word "cannibal." The Arawaks were soon exterminated by the Europeans who followed Columbus; the Caribs held out somewhat longer, and a few thousand survive today. In the sixteenth and seventeenth centuries the islands were appropriated by European powers-the English, French, Dutch, and Spanish. They became sugar islands, devoted to sugar plantations worked by negro slaves captured in West Africa and carried across the Atlantic in the dreadful circum- stances of the middle passage. After emancipation in the nineteenth century the sugar industry declined because the ex-slaves hated the sight of the sugar cane, which was being grown in increasing quantities in other parts of the tropics, and the sugar beet, efficiently cultivated in the temperate zone, began to rival the cane as a source of sucrose. During a long period of economic depression the Caribbean territories faded out of history, becoming of little importance to their European owners. Partial economic recovery came only recently, with the development of new industries such as bauxite manufac- ture, and the discovery, by wealthy Canadians and Americans, that the Caribbean offers an escape from winter blizzards and has lovely scenery. The tourist industry has boomed. During the last decade many of the Caribbean territories have become independent members of the United Nations. This, roughly, is the setting of the Caribbean Food and Nutrition Institute, established in 1967. The institute has centres in Jamaica and Trinidad, each located in the campus of the University of the West Indies. At present its activities I'Journal of Tropical Pediatrics, 1968, 14, 52. 2 Waterlow, J. C., Cravioto, J., and Stephen, J. M. L., Advances in Protein Chemistry, 1969, 15, 131. o n 5 A p ril 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://w w w .b m j.co m / B r M e d J: first p u b lish e d a s 1 0 .1 1 3 6 /b m j.3 .5 7 1 4 .5 9 o n 1 1 Ju ly 1 9 7 0 . 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Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_b4cf5w6y7zapbaztg6gzprtjy4 ---- JSE 314 online.indd BOOK REVIEW Ancient Ocean Crossings by Stephen C. Jett. Tuscaloosa, AL: University of Alabama Press, 2017. 508 pp. $49.94 (hardcover). ISBN 978-0-8173-1939-7. This review should properly be prefaced with two caveats. First, I am not a specialist in the field of human origins. I am not an archaeologist or anthropologist, but a geologist who is generally unfamiliar with the literature covered and reviewed in this book as well as the issues and controversies. Second, I did not read the entire book. This review is based on a reading of the introduction and conclusion while skimming the rest of the text. For those who find it unsettling that a reviewer has not read a book in its entirety, I can only tell you that it is very difficult to find people who are willing to donate the time necessary to read and review long technical books. (I’m still waiting on JSE to find reviewers for books I published in 2010). Anyone who is offended by my failure to peruse this volume from front to back covers may satisfy themselves with one-hundred percent of nothing by stopping their reading at this point. Ancient Ocean Crossings examines the evidence and arguments that human cultures in the Western Hemisphere were influenced by occasional contacts with ocean voyagers before Christopher Columbus arrived in the Americas in 1492. As the author notes, it’s now conceded that Vikings established a few settlements in North America hundreds of years before Columbus, yet these colonies were short-lived and apparently had little to no influence on American Indians. The ocean crossings referred to in the text are hypothetical voyages that may have occurred in the ten thousand years before Europeans first set foot in the Americas. There are some striking and unexplained cultural similarities between native peoples of the Old World and the Americas. These include “technical complexities of weaving and dyeing that are shared between southern Asia and the Central Andean region of South America,” “stepped temple pyramids that are oriented to the cardinal directions in both Mesoamerica and Cambodia,” and the belief “in both China and Mesoamerica, that raw jade can be discovered in nature owing to ‘exhalations’ coming from the stone” (p. 5). The two schools of thought regarding the origin of these similarities Journal of Scientifi c Exploration, Vol. 31, No. 4, pp. 700–702, 2017 0892-3310/17 are diffusionism and independent inventionism. Ancient Ocean Crossings is largely devoted to making the argument for the minority viewpoint of diffusionism. Diffusionists argue that it was possible for ideas and technology to diffuse between the hemi-spheres by pre-Columbian con-tact through ocean crossings. The text is divided into five parts. The first reviews “intellectual obstacles to the notion of early transoceanic contacts” (pp. 13–142). The second, third, and fourth sections treat means, motives, and opportunities for ocean crossings (pp. 143–356). The fifth section is a brief conclusion (pp. 357–361). Having presented the arguments and evidence, both pro and con, the author is entitled to draw a conclusion. He concludes that “crossings occurred,” and that “the sum of the evidence” is definitive (p. 359). The idea that the pre-Columbian peoples of the Eastern and Western Hemispheres “were hermetically sealed off” from each other rests “upon overly simple, insufficiently tested suppositions and incompletely thought- through conclusions concerning both physical geography and human capabilities” (p. 357). The question of whether or not ancient ocean crossings occurred is a reminder that evidence regarding human origins is scant. Important questions remain poorly resolved. The author of Ancient Ocean Crossings appears to implicitly accept the old idea that the Americas were first settled only in late Pleistocene time by migration across the Bering Strait (pp. 2–3). Yet as I have pointed out, there is a plethora of evidence suggesting a human presence in the Western Hemisphere as early as 200,000 years before present (Deming 2013). This was corroborated a few months ago when human artifacts 130,000 years old were found at the Cerutti Mastodon site in California (Holen et al. 2017). Another example is provided by recent finds from North Africa. Fossils from a single site in Morocco this year obliterated the idea that Homo 702 B o o k R e v i e w sapiens evolved in East Africa about 200,000 years ago. Excavations at the Jebel Irhoud site indicate that modern humans were in North Africa as early as 315,000 years before present (Stringer & Galway-Witham 2017). If fossils and artifacts from lone sites can completely rewrite our knowledge of human history and evolution, surely our theoretical framework rests upon shaky foundations. The entire issue of ancient ocean crossings is also a case study in how science works. Rather than adopt Chamberlin’s idealized model of multiple working hypotheses (1890), most scientists are narrowly focused specialists who operate within the realm of what Thomas Kuhn called “normal science” (Kuhn 1996:10). By the term “normal science,” Kuhn meant research based upon an existing intellectual framework. Most researchers see their work as the “further articulation and specification” of the prevailing paradigm (Kuhn 1996:23). Thus an archaeologist wedded to the idea that cultural novelties arise from independent inventionism will tend to automatically filter out and reject all evidence of cultural diffusionism. This mindset quickly evolves into a self-fulfilling prophecy whereby the diffusionist theory is rejected for lack of evidence. In summary, Ancient Ocean Crossings is a well-written and comprehensive review of an important issue in human origins. The author appears to have an in-depth and comprehensive knowledge of the pertinent scholarly literature. The text contains 35 pages of endnotes and the bibliography occupies 61 pages. This book is highly recommended to anyone interested in the history of the human race. DAVID DEMING College of Arts & Sciences, University of Oklahoma Norman, Oklahoma email: ddeming@ou.edu References Cited Chamberlin, T. C. (1890). The Method of Multiple Working Hypotheses. Science, 15:92–96. Deming, D. (2013). Did Modern Humans Originate in the Americas? A Retrospective on the Holloman Gravel Pit, Oklahoma. Journal of Scientific Exploration, 27:51–72. Holen, S. R., Demere, T. A., Fisher, D. C., Fullagar, R., Paces, J. B., Jefferson, G. T., Beeton, J. M., Cerutti, R. A., Rountrey, A. N., Vescera, L., & Holen, K. A. (2017). A 130,000-year-old Archaeological Site in Southern California, USA. Nature, 544:479–483. Kuhn, T. (1996). The Structure of Scientific Revolutions (Third Edition). Chicago: University of Chicago Press. Stringer, C., & Galway-Witham, J. (2017). On the Origin of Our Species. Nature, 546:212–214. work_b6dti3pbcjc75dimvvex4ukuwa ---- The British Atlantic World, 1500-1800 (review) The British Atlantic World, 1500-1800 (review) John Coffey The Scottish Historical Review, Volume 85, Number 1: No. 219, April 2006, pp. 155-156 (Review) Published by Edinburgh University Press DOI: For additional information about this article [ This content has been declared free to read by the pubisher during the COVID-19 pandemic. ] https://doi.org/10.1353/shr.2006.0008 https://muse.jhu.edu/article/199858 https://doi.org/10.1353/shr.2006.0008 https://muse.jhu.edu/article/199858 The British Atlantic World, 1500-1800. Edited by David Armitage and Michael J. Braddick. Pp. xx, 324. ISBN 0333963415. Houndmills: Palgrave Macmillan. 2002. £49.50. According to J.H. Elliot, the rise of the new Atlantic histor y is ‘one of the most important new historiographical developments of recent years’. Along with the new British histor y, it is forcing scholars of early modern England, Scotland, Ireland and North America out of the comfort zone of their national histories. It ‘pushes historians towards methodological pluralism and expanded hori- zons’ (p. 27), and challenges us to ‘trace connections’ and ‘draw comparisons’ (p. 236). David Armitage and Michael Braddick have edited an outstanding primer that will be warmly welcomed by first-time sailors and experienced navigators of this oceanic field. The collection is topped and tailed by two of the doyens of the new Atlantic histor y, Bernard Bailyn (who writes the Preface) and John Elliot (who provides the After word). Armitage himself contributes the introductor y essay, a sophisticated theoretical analysis of the new subject. But the heart of the book lies in ten thematic essays arranged into three categories. The first cate- gor y, ‘Connections’, contains pieces on migration (Alison Games), the economy (Nuala Zahedieh) and religion (Carla Pestana); the second, ‘Iden- tities’, covers civility and authority (Braddick), gender (Sarah Pearsall), class (Keith Wrightson) and race (Joyce Chaplin); and the third, ‘Politics’, tackles empire and state (Elizabeth Mancke), revolution and counter-revolution (Eliga Gould) and slaver y (Christopher Brown). The topics covered indicate the diversity and ambition of the new Atlantic histor y. If the emergence of the new British histor y was largely driven by the questions of political historians (especially concerning the origins of the English Civil War), Atlantic histor y is more wide-ranging in its origins and scope—both thematically and geographically. The essays assembled in this unusually coherent collection provide wonderfully compressed over views of their topics. Inevitably, some subjects lend themselves to the Atlantic approach more than others—as Elliot obser ves, migration and slaver y are particularly well suited to this kind of treatment, and it is no surprise that the essays by Games and Brown are among the most satisfying. But the quality of the collection as a whole is ver y high, and each piece is packed with striking detail and provocative generalisation. Elliot even offers a speculative piece of ‘counter-factual Atlantic histor y’ in which Christopher Columbus enters the ser vice of Henr y VII of England and an expedition of five hundred West Countr ymen conquers the Aztecs, with world-historical consequences (pp. 241-43). There are also, however, some questionable statements. Gould suggests that ‘Few historians would dispute the interconnectedness of what they now describe as the “three British revolutions” of 1641, 1688, and 1776’ (p. 196). In fact, few scholars apart from John Pocock (to whom Gould refers) show the slightest interest in the connections between 1641 and 1776, and many historians of the English Civil War would insist that if a ‘revolution’ took place at all it did not do so until 1648-49. On another matter, historians of the Covenanter Parliaments will be surprised at the claim that the Glorious Revolution ‘opened the way for the first truly independent parliaments in Scottish histor y’ (p. 203). In other essays, the vastness of the subject inspires grandiose phrases—‘inter-hemispheric civilisation’ (p. xiv) will presumably appeal to sci- ence-fiction fans. The new subject is even generating new jargon. We read of ‘circum-Atlantic histor y’, ‘Trans-Atlantic histor y’, ‘Cis-Atlantic histor y’, the ‘white’ Atlantic, the ‘black’ Atlantic, the ‘red’ Atlantic, the ‘multicoloured’ R E V I E W S 1 5 5 Mary Botto muse_logo Atlantic and even the ‘green’ Atlantic (a reference to the Irish, not to ecology). One can only be grateful that there is as yet no sign of a ‘tartan Atlantic’. Scotland, in fact, does not loom particularly large. It receives reasonable cov- erage in the essays on migration and revolution, but in several others the Scots make only a token appearance. The index contains more references to Ireland, not least because it was such an important trial-ground for English colonialism. Scotland’s relatively low profile reflects the fact that for much of the period from 1500 to 1800 the majority of Scots were facing East rather than West. As Games suggests, ‘In their Atlantic orientation the English were distinct from the Scots, who were precociously European in orientation’ (p. 37). Of course, the Scots made up for lost time in the eighteenth and nineteenth centuries, though the authors of this volume were unable to benefit from the latest studies of Scottish overseas migration, such as Tom Devine’s Scotland’s Empire, 1600-1815 (2003) and Marjor y Harper’s Adventurers and Exiles: The Great Scottish Exodus (2003). Despite this, historians of Scotland will find this to be a ver y stimulating col- lection. It provides a broader framework for national histories, and succeeds admirably in its task of pushing historians towards expanded horizons. University of Leicester JOHN COFFEY The ‘Conquest’ of Acadia, 1710: Imperial, Colonial, and Aboriginal Constructions. By John G. Reid, Maurice Basque, Elizabeth Mancke, Barry Moody, Geoffrey Plank and William Wicken. Pp. xxiii, 297. ISBN 0802037550 cloth; 0802085385 paper. Toronto: University of Toronto Press. 2004. £40.00 cloth; £20.00 paper. This collection of nine essays, by six United States and Canadian scholars, examines the British conquest of the French colony of Acadia and the subse- quent problems which beset the administrators of the renamed Nova Scotia. The authors take a rather post-modernist approach to the conquest, arguing that there is no ‘single valid narrative’ of the conquest and that ‘the events that are central to this book were experienced differently by native inhabitants, Aca- dians, and British and French officials, and by British colonists in New England and then in Nova Scotia’ (p. xi). Consequently, each chapter takes a different approach and studies a different aspect of the conquest and its legacy. Although the work is a collection of separate essays, it does have a clear central focus, and the essays develop several central themes. In particular, the authors also place the Acadian experience in the broader context of the eigh- teenth-centur y Atlantic world and arrive at two central conclusions. As they explain, ‘The first is the bankruptcy of the notion that this period in histor y was the “colonial” era. Colonies existed, but they existed in relationship to imperial and native worlds that interacted with each other as well as with colonial popula- tion’ (p. 208). The second is that the interaction between British, Acadian and Mik’maqs ‘by conforming neither with the accepted pattern of a colony of settle- ment nor with that of a “middle ground” provides the historian with an interme- diate model. Here European settlement existed and so did imperial institutions of governance. The Acadian communities, however, represented a form of set- tlement that had become divorced from state formation and from formal impe- rial expansion’ (pp. 208-9). The authors also stress the pivotal role of negotiation in shaping their model of imperialism. Central to all negotiations in the region was the weakness of the British administration in Nova Scotia. Deprived of both money and men, British administrators were unable to impose their rule on the Acadians or Native 1 5 6 R E V I E W S work_bfn5azrznbgktcgg32gowyrhzq ---- wp-p1m-38.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-38.ebi.ac.uk no 218200190 Params is empty 218200190 exception Params is empty 2021/04/06-02:09:26 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. Message ID: 218200190 (wp-p1m-38.ebi.ac.uk) Time: 2021/04/06 02:09:26 If you need further help, please send an email to PMC. Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_binry3w65bdfrbyb2kcpq424ry ---- National Curriculum - History key stages 1 to 2 Published: September 2013 History programmes of study: key stages 1 and 2 National curriculum in England Purpose of study A high-quality history education will help pupils gain a coherent knowledge and understanding of Britain’s past and that of the wider world. It should inspire pupils’ curiosity to know more about the past. Teaching should equip pupils to ask perceptive questions, think critically, weigh evidence, sift arguments, and develop perspective and judgement. History helps pupils to understand the complexity of people’s lives, the process of change, the diversity of societies and relationships between different groups, as well as their own identity and the challenges of their time. Aims The national curriculum for history aims to ensure that all pupils:  know and understand the history of these islands as a coherent, chronological narrative, from the earliest times to the present day: how people’s lives have shaped this nation and how Britain has influenced and been influenced by the wider world  know and understand significant aspects of the history of the wider world: the nature of ancient civilisations; the expansion and dissolution of empires; characteristic features of past non-European societies; achievements and follies of mankind  gain and deploy a historically grounded understanding of abstract terms such as ‘empire’, ‘civilisation’, ‘parliament’ and ‘peasantry’  understand historical concepts such as continuity and change, cause and consequence, similarity, difference and significance, and use them to make connections, draw contrasts, analyse trends, frame historically-valid questions and create their own structured accounts, including written narratives and analyses  understand the methods of historical enquiry, including how evidence is used rigorously to make historical claims, and discern how and why contrasting arguments and interpretations of the past have been constructed History – key stages 1 and 2 2  gain historical perspective by placing their growing knowledge into different contexts, understanding the connections between local, regional, national and international history; between cultural, economic, military, political, religious and social history; and between short- and long-term timescales. Attainment targets By the end of each key stage, pupils are expected to know, apply and understand the matters, skills and processes specified in the relevant programme of study. Schools are not required by law to teach the example content in [square brackets] or the content indicated as being ‘non-statutory’. Subject content Key stage 1 Pupils should develop an awareness of the past, using common words and phrases relating to the passing of time. They should know where the people and events they study fit within a chronological framework and identify similarities and differences between ways of life in different periods. They should use a wide vocabulary of everyday historical terms. They should ask and answer questions, choosing and using parts of stories and other sources to show that they know and understand key features of events. They should understand some of the ways in which we find out about the past and identify different ways in which it is represented. In planning to ensure the progression described above through teaching about the people, events and changes outlined below, teachers are often introducing pupils to historical periods that they will study more fully at key stages 2 and 3. Pupils should be taught about:  changes within living memory. Where appropriate, these should be used to reveal aspects of change in national life  events beyond living memory that are significant nationally or globally [for example, the Great Fire of London, the first aeroplane flight or events commemorated through festivals or anniversaries]  the lives of significant individuals in the past who have contributed to national and international achievements. Some should be used to compare aspects of life in different periods [for example, Elizabeth I and Queen Victoria, Christopher Columbus and Neil Armstrong, William Caxton and Tim Berners-Lee, Pieter Bruegel the Elder and LS Lowry, Rosa Parks and Emily Davison, Mary Seacole and/or Florence Nightingale and Edith Cavell]  significant historical events, people and places in their own locality. History – key stages 1 and 2 3 Key stage 2 Pupils should continue to develop a chronologically secure knowledge and understanding of British, local and world history, establishing clear narratives within and across the periods they study. They should note connections, contrasts and trends over time and develop the appropriate use of historical terms. They should regularly address and sometimes devise historically valid questions about change, cause, similarity and difference, and significance. They should construct informed responses that involve thoughtful selection and organisation of relevant historical information. They should understand how our knowledge of the past is constructed from a range of sources. In planning to ensure the progression described above through teaching the British, local and world history outlined below, teachers should combine overview and depth studies to help pupils understand both the long arc of development and the complexity of specific aspects of the content. Pupils should be taught about:  changes in Britain from the Stone Age to the Iron Age Examples (non-statutory) This could include:  late Neolithic hunter-gatherers and early farmers, for example, Skara Brae  Bronze Age religion, technology and travel, for example, Stonehenge  Iron Age hill forts: tribal kingdoms, farming, art and culture  the Roman Empire and its impact on Britain Examples (non-statutory) This could include:  Julius Caesar’s attempted invasion in 55-54 BC  the Roman Empire by AD 42 and the power of its army  successful invasion by Claudius and conquest, including Hadrian’s Wall  British resistance, for example, Boudica  ‘Romanisation’ of Britain: sites such as Caerwent and the impact of technology, culture and beliefs, including early Christianity History – key stages 1 and 2 4  Britain’s settlement by Anglo-Saxons and Scots Examples (non-statutory) This could include:  Roman withdrawal from Britain in c. AD 410 and the fall of the western Roman Empire  Scots invasions from Ireland to north Britain (now Scotland)  Anglo-Saxon invasions, settlements and kingdoms: place names and village life  Anglo-Saxon art and culture  Christian conversion – Canterbury, Iona and Lindisfarne  the Viking and Anglo-Saxon struggle for the Kingdom of England to the time of Edward the Confessor Examples (non-statutory) This could include:  Viking raids and invasion  resistance by Alfred the Great and Athelstan, first king of England  further Viking invasions and Danegeld  Anglo-Saxon laws and justice  Edward the Confessor and his death in 1066  a local history study Examples (non-statutory)  a depth study linked to one of the British areas of study listed above  a study over time tracing how several aspects of national history are reflected in the locality (this can go beyond 1066)  a study of an aspect of history or a site dating from a period beyond 1066 that is significant in the locality. History – key stages 1 and 2 5  a study of an aspect or theme in British history that extends pupils’ chronological knowledge beyond 1066 Examples (non-statutory)  the changing power of monarchs using case studies such as John, Anne and Victoria  changes in an aspect of social history, such as crime and punishment from the Anglo-Saxons to the present or leisure and entertainment in the 20th Century  the legacy of Greek or Roman culture (art, architecture or literature) on later periods in British history, including the present day  a significant turning point in British history, for example, the first railways or the Battle of Britain  the achievements of the earliest civilizations – an overview of where and when the first civilizations appeared and a depth study of one of the following: Ancient Sumer; The Indus Valley; Ancient Egypt; The Shang Dynasty of Ancient China  Ancient Greece – a study of Greek life and achievements and their influence on the western world  a non-European society that provides contrasts with British history – one study chosen from: early Islamic civilization, including a study of Baghdad c. AD 900; Mayan civilization c. AD 900; Benin (West Africa) c. AD 900-1300. © Crown copyright 2013 You may re-use this information (excluding logos) free of charge in any format or medium, under the terms of the Open Government Licence. To view this licence, visit www.nationalarchives.gov.uk/doc/open- government-licence/ or email: psi@nationalarchives.gsi.gov.uk. Reference: DFE-00173-2013 http://www.nationalarchives.gov.uk/doc/open-government-licence/ http://www.nationalarchives.gov.uk/doc/open-government-licence/ mailto:psi@nationalarchives.gsi.gov.uk Purpose of study Aims Attainment targets Subject content Key stage 1 Key stage 2 Examples (non-statutory) This could include: Examples (non-statutory) Examples (non-statutory) Examples (non-statutory) Examples (non-statutory) Examples (non-statutory) work_bjajsm5245avnlclythhnpipra ---- RESEARCH REPORT Secular trends in sex ratios at birth in North America and Europe over the second half of the 20th century V Grech, P Vassallo-Agius, C Savona-Ventura . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . J Epidemiol Community Health 2003;57:612–615 Context: A previous study showed that significantly more boys were born in southern latitudes in Europe than in northern latitudes and the converse pattern was observed in North America. Objective: This study analyses secular trends in gender ratios for live births over the second half of the 20th century. Design, setting, participants: Analysis was carried out from a World Health Organisation dataset comprising live births over the above period. This included 127 034 732 North American and 157 947 117 European live births. Main outcome measures: Analysis of trends in gender ratios for countries in both continents. Results: The findings show a highly significant overall decline in male births in both Europe and North America (p<0.0001), particularly in Mexico (p<0.0001). Interestingly, in Europe, male births declined in North European countries (latitude>40°, p<0.0001) while rising in Mediterranean countries (latitude ≅35–40°, p<0.0001). These trends produced an overall European male live birth deficit 238 693 and a North American deficit of 954 714 (total male live birth deficit 1 193 407). Conclusions: No reasonable explanation/s for the observed trends have been identified and the causes for these trends may well be multifactorial. S ex in reptiles and fish is determined after conception, during embryogenesis, according to ambient environ- mental temperature.1 In contrast, in mammals and birds, sex is determined at conception. In mammals, male births invariably occur slightly in excess.2 The male to female ratio of live births is generally expressed as the ratio of male live births divided by total live births (M/F), and the human M/F is expected to be 0.515, with approximately 3% more males born than females.3 The reason for this discrepancy is uncertain as testicles produce equal numbers of X-bearing and Y-bearing spermatozoa.4 Several theories have been put forward to explain why this ratio should not be 0.5, with equal number of male and female births. These theories include the timing of conception within the ovulatory cycle,3 endocrine effects,5 and immunological effects.6 We have shown that M/F varies in geographical space, exhibiting a latitude gradient,7 and that this gradient is differ- ent in Europe and North America, with more males born towards the south of Europe, compared with the North American continent where more males are born towards the north of the continent.8 Other studies have also shown that M/F may vary with time. Several authors have shown that M/F has declined over the second half of the 20th century in various industrialised countries. These include Denmark,9 the United Kingdom,10 the Netherlands,11 Germany,12 Canada,13 the United States of America,14 and Finland.15 In contrast, M/F has been noted to have risen in Ireland over the same period.16 A non-significant rise in M/F has also been noted in Australia17 and Japan.18 James has proposed that M/F fluctuates over a 30 year cycle.19 In this study, we identify secular trends in M/F in dif- ferent countries and continents from a World Health Organis- ation dataset for the second half of the 20th century. We also analysed these trends by geographical latitude in Europe and briefly review the relevant literature regarding this topic. METHODS Data sources Annual male and female live births were obtained directly from WHO. Data were available for 1950–97 for the North American continent (Canada, USA, and Mexico), and for European countries for the period 1950–99, with the following exceptions: Data were not available for Mexico for the period 1950–8 and for 1996–7. Data were not available for the years 1998–9 for the following countries: France and Spain. Data were not available for 1999 for the following countries: the Nether- lands, Poland, United Kingdom, Germany, Norway, and Greece. Data for Romania were not available for the period 1950–54. Stillbirths are not included in this study and neither were data from small countries. Statistics The quadratic equations of Fleiss were used for exact calcula- tion of 95% confidence limits for ratios. 20 Linear regression was used for the calculation of association of annual M/F with time. Graphs are drawn as five year moving averages. A p value <0.05 was taken to represent a statistically significant result. RESULTS There has been a significant decline in M/F ratios during the second part of the 20th century in both the European and North American continents (fig 1). Live birth data and regression calculations for countries studied are shown in table 1. Europe This continent included a study (live birth) population of 157 947 117. A statistically significant decrease in M/F was noted in Greece, Hungary, Poland, and Sweden. A decline in M/F, albeit not statistically significant, was found in Austria, Belgium, Bulgaria, Norway, Portugal, Romania, and Switzer- land. In contrast, M/F rose significantly in France and Italy. M/F rose and then fell in Spain, with an overall significant rise. See end of article for authors’ affiliations . . . . . . . . . . . . . . . . . . . . . . . Correspondence to: Dr V Grech, Paediatric Department, St Luke’s Hospital, Guardamangia, Malta; victor.e.grech@govt.mt Accepted for publication 2 January 2003 . . . . . . . . . . . . . . . . . . . . . . . 612 www.jech.com o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://je ch .b m j.co m / J E p id e m io l C o m m u n ity H e a lth : first p u b lish e d a s 1 0 .1 1 3 6 /je ch .5 7 .8 .6 1 2 o n 2 5 Ju ly 2 0 0 3 . D o w n lo a d e d fro m http://jech.bmj.com/ Summation of live births for Mediterranean countries that span latitude ≅35–40° (Bulgaria, Greece, Italy, Portugal, and Spain) showed a significant rise in M/F. Live births for the remaining European countries above latitude 40° (Austria, Belgium, Denmark, Finland, France, Germany, Hungary, Ireland, the Netherlands, Norway, Poland, Romania, Sweden, Switzerland, and the United Kingdom) showed a significant fall in M/F (fig 2). Assuming an expected M/F of 0.515, these trends produced a male birth deficit of 12 744 in the Mediterranean region, 212 780 in central Europe and 13 169 in the Nordic countries; a total male birth deficit of births 238 693. North America This continent included a study (live birth) population of 127 034 732. The combined North American continent data (Mexico, USA, and Canada) showed a significant decline in M/F (fig 1). M/F declined significantly in the USA and Mexico (fig 3). Once again, assuming an expected M/F of 0.515, these trends produced a male birth deficit of 21 993 in Canada, 410 932 in the United States, and 521 789 in Mexico; a total male birth deficit of 954 714. The combined live male birth deficit for the two continents was 1 193 407. Figure 1 M/F ratios for Europe (combined), North America (combined), and both continents combined. Table 1 Male, female, total births and linear regression of sex ratio with time for countries included in this study Country Male live births Female live births Total live births r p M/F 95% CI Denmark* 1680922 1588490 3269412 −0.29 0.49 0.5141 0.5136 to 0.5147 Finland* 1741682 1652473 3394155 −0.10 0.50 0.5131 0.5126 to 0.5137 Germany* 25678261 24239453 49917714 −0.75 <0.0001 0.5144 0.5143 to 0.5146 Ireland* 1498481 1416062 2914543 0.45 0.002 0.5141 0.5136 to 0.5147 Netherlands* 5160590 4899973 10060563 −0.60 <0.0001 0.5130 0.5126 to 0.5133 UK* 20441737 19330020 39771757 −0.61 <0.0001 0.5140 0.5138 to 0.5141 Austria 2600186 2466512 5066698 −0.13 0.38 0.5132 0.5128 to 0.5136 Belgium 3138073 2965932 6104005 −0.17 0.26 0.5141 0.5137 to 0.5145 Bulgaria 3176760 3000118 6176878 −0.22 0.13 0.5143 0.5139 to 0.5147 France 19579581 18634567 38214148 0.52 <0.0001 0.5124 0.5122 to 0.5125 Greece 3395944 3168572 6564516 −0.43 0.002 0.5173 0.5169 to 0.5177 Hungary 3815036 3587994 7403030 −0.65 <0.0001 0.5153 0.5150 to 0.5157 Italy 18671513 17652250 36323763 0.73 <0.0001 0.5140 0.5139 to 0.5142 Norway 1444600 1363935 2808535 −0.15 0.31 0.5144 0.5138 to 0.5149 Poland 15295234 14359427 29654661 0.80 <0.0001 0.5158 0.5156 to 0.5160 Portugal 4283717 4015694 8299411 −0.03 0.81 0.5161 0.5158 to 0.5165 Romania 8082232 7649545 15731777 −0.27 0.07 0.5138 0.5135 to 0.5140 Spain 13600342 12805240 26405582 0.69 <0.0001 0.5151 0.5149 to 0.5152 Sweden 2607559 2459796 5067355 −0.51 <0.0001 0.5146 0.5141 to 0.5150 Switzerland 2103563 1995775 4099338 −0.07 0.65 0.5131 0.5127 to 0.5136 Mediterranean (35-40°) 43128276 40641874 83770150 0.66 <0.0001 0.5147 0.5148 to 0.5149 Northern Europe (>40°) 114818841 108564205 223383046 −0.84 <0.0001 0.5139 0.5140 to 0.5141 All Europe 157947117 149206079 307153196 −0.68 <0.0001 0.5142 0.5142 to 0.5143 Canada (>50°)* 8012882 7588817 15601699 0.26 0.79 0.5136 0.5133 to 0.5138 USA (30-50°)* 76827922 73150435 149978357 −0.73 <0.0001 0.5123 0.5122 to 0.5123 Mexico (<30°) 42193928 40749212 82943140 −0.76 <0.0001 0.5087 0.5086 to 0.5088 North America 127034732 121488464 248523196 −0.73 <0.0001 0.5112 0.5111 to 0.5112 *Previously reported. Figure 2 Summation of M/F ratios for Mediterranean and northern European countries. Figure 3 M/F ratios for Canada, the United States of America, and Mexico. Trends in sex ratios at birth 613 www.jech.com o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://je ch .b m j.co m / J E p id e m io l C o m m u n ity H e a lth : first p u b lish e d a s 1 0 .1 1 3 6 /je ch .5 7 .8 .6 1 2 o n 2 5 Ju ly 2 0 0 3 . D o w n lo a d e d fro m http://jech.bmj.com/ DISCUSSION In utero, the male fetus is more prone to morbidity and mor- tality from external influences than the female fetus. Moreover, the male fetus is at greater risk of all obstetric com- plications than the female fetus and readers are referred to the review by Kraemer.21 Despite these adverse factors, males are invariably born in excess of females,2 implying an even higher conception rate of males over females than evinced by the sex ratio at birth. In the first half of the 20th century, antenatal care improved dramatically in industrialised countries, which led to a fall in stillbirths, most of which would have otherwise been male. This therefore led to an increase in the M/F ratio. 9 22 M/F then declined in several countries in the second half of the 20th century, and one study has proposed that M/F could be used as a sentinel health indicator.23 This is supported by data from Italy that showed that in metropolitan areas, M/F declined in comparison with the rest of the country where M/F increased.24 However, there are several arguments against this hypoth- esis. Firstly, in Finland15 and in Malta,7 the decline in M/F pre- dated the countries’ industrialisation or the widespread use of pesticides. Secondly, it has been noted that in the United States, M/F was overall higher in the black population than in the white population,14 and that M/F rose and then fell in the white population (1964–1988), while rising throughout the study period in the non-white population.25 The overall decline is accounted for by the fact that over 80% of the USA popula- tion falls in the “white” category. Thirdly, Ireland has reported a rise in M/F despite increasing industrialisation,16 and in this study, M/F was also seen to rise in France, Italy, and Spain. These findings do not support the sentinel health indicator hypothesis. Our earlier study provoked several useful comments.8 Jacobs commented that the differences that we showed were very small,26 which is perfectly true. However, this small difference has resulted in an overall deficit of 1 193 407 male births in the European and North American continents for this same study period.8 Voracek and Fisher commented that as the onset of the study period in the 1950s is slightly differ- ent for Europe and North America, the peak in male live births after the second world war may have skewed our results. However, after the war, the ratio rapidly declined to the base- line and is therefore unlikely to have affected our overall results. 11 12 They also pointed out that that the area of the North American continent is 4.8 times the 24 European coun- tries in our study. However, the data on which the paper is based show that the number of actual births is quite similar (North America 127 034 732, Europe 157 947 117, ratio 0.80). They also reanalysed the dataset and showed a curvilinear relation of latitude and sex ratio that is consistent with an effect related to photoperiod. However, the secular trends can- not be explained, to our mind, by such an effect. 27 Shields et al showed a significant relation between cytomegalovirus sero- positivity in cord blood and female sex, but again, we cannot see how CMV infection may possibly be implicated in these secular trends.28 James also reiterated the influence of maternal oestrogen levels on birth weight and the likelihood of dizygotic twins.29 While an interesting hypothesis, we cannot see how this fac- tor alone could explain the widely varying secular trends in different countries over the same timespans. An earlier study had noted declining trends in several countries in various continents, but a latitude effect had not been perceived.30 This same study also showed no overall change in M/F over 1926–1990, whereas our study only looked at the second half of 20th century. It may be that Parazzini et al’s early part of the dataset trends nullified the trends in the second half of 20th century.31 External factors that influence M/F have also been described. Germany, for example, experienced two M/F peaks that were related to the two world wars,12 and these peaks were also supported by data from the Netherlands.32 James has proposed that M/F fluctuates over a 30 cycle, and that this is attributable to a homeostatic mechanism that cor- relates sex at birth negatively with the adult sex ratio at the time of conception.33 The current decline in M/F would there- fore be a negative feedback response to the increase in M/F in the first half of the 20th century. This hypothesis is partly supported by data from the USA that demonstrated a degree of cyclicity over a 55 year period.30 More interestingly, this same study showed a strong degree of correlation between parental age and birth weight. However, the overall decline in M/F in our 50 year study seems constant in both Europe and North America (fig 1) with no evidence of a 30 year cycle. Diverging cultural attitudes may also potentially influence M/F. For example, Latino and Eastern cultures prefer male over female offspring. 34 35 In such cultures, families would be more likely to settle for a single son, than for a single daugh- ter, and on first having a daughter, may therefore opt to have additional children in order to have a son. Male offspring bias may also be evinced by female infanticide and/or sex selective abortion. However, it is unlikely that such factors could have played an important part in determining the observed M/F ratios in the developed countries considered in this study. 36 37 Moreover, any such skew would have mitigated against our finding of an overall male deficit. Several other hypothesis have been put forward to explain different trends in M/F ratios, with various factors assumed to influence the female genital tract environment in ways to favour the Y-bearing spermatozoa.25 For example, it has been claimed that caloric availability per capita correlates positively with M/F.37 In an earlier study we showed a latitude gradient for both Europe and the North American continent.8 Our current European results are interesting in that they show a rising M/F ratio in Mediterranean countries and a falling M/F ratio in more northern European countries (fig 2). Since the early 1980s, in Mediterranean countries, M/F ratio seems to have stabilised at just over the expected value of 0.515, while in more northern countries, M/F ratio seems to have stabilised at 0.513. Should these secular trends increase in magnitude, with an increasing male deficit, this will naturally have social, occupational, epidemiological, and community health related effects. The results of this study yield highly significant p values because of the large numbers of births involved despite the comparatively small shifts in secular trends. The p values are usually used to enable inferences to be drawn about popu- lations from samples. In this context, the p value is only use- ful as an indicator that shows how likely it is that these results should occur by chance alone, assuming that the dataset is correct. One final point that must be borne in mind is that the differences that we demonstrated are very small, and could theoretically have been produced by even very small differen- tial reporting in male and female births, although such errors are unlikely to produce the observed, rather smooth secular trends. In conclusion, while we have expanded our findings on the sex ratio at birth by studying secular trends, we still cannot put forward any reasonable explanation for the observed trends, which may well be attributable to several factors and not just one. . . . . . . . . . . . . . . . . . . . . . Authors’ affiliations V Grech, Paediatric Department, St Luke’s Hospital, Malta P Vassallo-Agius, Medical School, University of Malta C Savona-Ventura, Department of Obstetrics and Gynaecology, St Luke’s Hospital, Malta REFERENCES 1 Dournon C, Houillon C, Pieau C. Temperature sex-reversal in amphibians and reptiles. Int J Dev Biol 1990;34:81–92. 614 Grech, Vassallo-Agius, Savona-Ventura www.jech.com o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://je ch .b m j.co m / J E p id e m io l C o m m u n ity H e a lth : first p u b lish e d a s 1 0 .1 1 3 6 /je ch .5 7 .8 .6 1 2 o n 2 5 Ju ly 2 0 0 3 . D o w n lo a d e d fro m http://jech.bmj.com/ 2 Parkes AS. The mammalian sex ratio. Hum Reprod 1926;2:1–51. 3 James WH. The human sex ratio. Part 1: a review of the literature. Hum Biol 1987;59:721–52. 4 Wyrobek AJ, Robbins WA, Mehraein Y, et al. Detection of sex chromosomal aneuploidies X-X, Y-Y, and X-Y in human sperm using two-chromosome fluorescence in situ hybridization. Am J Med Genet 1994;53:1–7. 5 James WH. Parental hormone levels and mammalian sex ratios at birth. J Theor Biol 1989;139:59–67. 6 Ober C. The maternal-fetal relationship in human pregnancy: an immunogenetic perspective. Exp Clin Immunogenet 1992;9:1–14. 7 Grech V, Vassallo-Agius P, Savona-Ventura C. Declining male births with increasing geographical latitude in Europe. J Epidemiol Community Health 2000;54:244–6. 8 Grech V, Vassallo-Agius P, Savona-Ventura C. BMJ 2002;324:1010– 11. 9 Moller H. Change in male:female ratio among newborn infants in Denmark. Lancet 1996;348:828–9. 10 Dickinson HO, Parker L. Why is the sex ratio falling in England and Wales? J Epidemiol Community Health 1996;50:227–8. 11 van der Pal-de Bruin KM, Verloove-Vanhorick SP, Roeleveld N. Change in male:female ratio among newborn babies in Netherlands. Lancet 1997;349:62. 12 Bromen K, Jockel KH. Change in male proportion among newborn infants. Lancet 1997;349:804–5. 13 Allan BB, Brant R, Seidel JE, et al. Declining sex ratios in Canada. Can Med Assoc J 1997;156:37–41. 14 Marcus M, Kiely J, Xu F, et al. Changing sex ratio in the United States, 1969–1995. Fertil Steril 1998;70:270–3. 15 Vartiainen T, Kartovaara L, Tuomisto J. Environmental chemicals and changes in sex ratio: analysis over 250 years in Finland. Environ Health Perspect 1999;107:813–15. 16 Moynihan JB, Breathnach CS. Changes in male:female ratio among newborn infants in Ireland. APMIS 1999;107:365–8. 17 Lancaster PA, Day PL. Declines in population sex ratios at birth. JAMA 1998;280:1139–40. 18 Minakami H, Sato I. Change in male proportion of newborn infants in Japan. Am J Obstet Gynecol 1998;178:624. 19 James WH. Declines in population sex ratios at birth. JAMA 1998;280:1139. 20 Fleiss JL. Statistical methods for rates and proportions. 2nd edn. New York: Wiley, 1981:14–15. 21 Kraemer S. The fragile male. BMJ 2000;321:1609–12. 22 National Center for Health Statistics. Vital statistics of the United States, 1992: mortality part A. Vol 2. Washington, DC: Public Health Service, 1996. 23 Davis DL, Gottlieb MB, Stampnitzky JR. Reduced ratio of male to female births in several industrial countries: a sentinel health indicator? JAMA 1998;279:1018–23. 24 Astolfi P, Zonta LA. Reduced male births in major Italian cities. Hum Reprod 1999;14:3116–19. 25 Nicolich MJ, Huebner WW, Schnatter AR. Influence of parental and biological factors on the male birth fraction in the United States: an analysis of birth certificate data from 1964 through 1988. Fertil Steril 2000;73:487–92. 26 Jacobs A. Different sex ratios at birth in Europe and North America. [Letter]. BMJ 2002;325:334. 27 Voracek M, Fisher ML. Different sex ratios at birth in Europe and North America. [Letter]. BMJ 2002;325:334. 28 Shields MD, O’Hare B, Nelson J, et al. Different sex ratios at birth in Europe and North America. [Letter]. BMJ 2002;325:334. 29 James WH. Sex ratio at birth and latitude. [Letter]. J Epidemiol Community Health 2001;55:216. 30 Parazzini F, La Vecchia C, Levi F, et al. Trends in male:female ratio among newborn infants in 29 countries from five continents. Hum Reprod 1998;13:1394–6. 31 Parazzini F, La Vecchia C, Chatenoud L, et al. Change in male proportion among newborn infants. Lancet 1997;349:805–6. 32 van den Broek JM. Change in male proportion among newborn infants. Lancet 1997;349:805. 33 James WH. What stabilizes the sex ratio? Ann Hum Genet 1995;59:243–9. 34 Sachar RK, Soni RK. The role of secondary sex ratios in the declining sex ratio of India. Indian J Public Health 1995;39:12–15. 35 Coale AJ, Banister J. Five decades of missing females in China. Demography 1994;31:459–79. 36 Rinehart W. Sex preselection–not yet practical. Popul Rep I 1975;2:21–32. 37 Williams RJ, Gloster SP. Human sex ratio as it relates to caloric availability. Soc Biol 1992;39:285–91. APHORISM OF THE MONTH ......................................................................... Starting a rumour, following Christopher Columbus, and spending other people’s money R eaders will recall that Columbus was adept at following his strategy for exploration by spending other people’s money.1 Bridging the gap between starting a rumour and mobi- lising resources for change is at the heart of public health—how often have you heard somebody say that they can’t do anything to improve health without knowing where the money is coming from first, yet public health is essentially about shaping and influencing the actions of others and other sectors. An effective public health practitioner should be adept at spending other people’s money, but for this to happen on any meaningful scale it is essential for other players involved to feel a sense of ownership.2 I have long contended that in health and health care we need not Directors of Finance, but Directors of Resources. The mindset that starts with financial resources in health finishes up with doctors, nurses, bricks and mortar, and bits of kit. In reality, the resources for health run much wider, including many human and environmental resources that lie outside the bailiwick of something called health. JRA References 1 Ashton JR. Columbus on the need for strategy. J Epidemiol Community Health 2003;57:235. 2 Ashton JR. Communities and sustaining change. J Epidemiol Community Health 2002;56:561. Trends in sex ratios at birth 615 www.jech.com o n A p ril 5 , 2 0 2 1 b y g u e st. P ro te cte d b y co p yrig h t. h ttp ://je ch .b m j.co m / J E p id e m io l C o m m u n ity H e a lth : first p u b lish e d a s 1 0 .1 1 3 6 /je ch .5 7 .8 .6 1 2 o n 2 5 Ju ly 2 0 0 3 . D o w n lo a d e d fro m http://jech.bmj.com/ work_bjrzctqlmrej3cqmrxtf5pedri ---- Science and Industry N o . 4 RADIO ADDRESS : SCIENCE AND THE WAR 161 SCIENCE AND INDUSTRY THOMAS MIDGLEY, JR. Q. Our discussion today, Dr. Midgley, is about the role of science in industry. What have been among the outstanding contributions of science to industry, and where do the contributions of science to industry start? A. Since mankind first developed co-operation, there have been activities such as the making of arrowheads that have been called industry. However, it was not until nearly two hundred years ago that what we now call industry started in England. This was founded on the application of power to production. I mean power other than man or animal power. This was done by James Watt developing the steam engine. This was not the result of young Watt watching the lid of his mother's teakettle blow off but actually was the result of applying science. Watt was an instrument maker at the University of Glasgow and was assigned a job of studying the operation of a steam engine used for pumping water out of mines. Watt decided that this device was inefficient and cumbersome and needed improve- ment. He spent two years in researching on the properties of steam and with the aid of this scientific knowledge was able to produce an engine that would not com- pare unfavorably with some of the present day. This made it possible to gather 162 THOMAS MIDGLEY, JR. Vol. X L I I people together in factories where steam power could be used and thus produce quantities of finished goods, the like of which had never before been seen. Thus what we call industry was actually founded upon a scientific development. Q. Most of us, Doctor, think of science in industry as being solely in the lab- oratory and not something t h a t is brought into the factory itself. Is this true? A. No. For example, many years ago Mr. C. F . Kettering, who invented and developed the self starter, was calling on Mr. Nash in the expectation of obtaining a contract for t h a t year's business. I t so happened, t h a t a competitive starter was being offered to Mr. Nash at $1.00 less than Mr. Kettering's. The arguments waxed thick and strong. Mr. Kettering continually telling Mr. Nash how much research Delco did in its laboratories to improve its products and Mr. Nash repeatedly saying, " I ' m not paying t h a t dollar just to run your laboratory." Finally with things deadlocked, Mr. Nash started talking about some troubles they were having with their rear axles and asked Mr. Kettering if he could make any suggestions. They walked through the shop to the heat-treating room and Mr. Kettering saw t h a t they were judging the temperatures of the axle pieces being heat treated b y eye so t h a t on bright days they were bound to get the axles hotter, before quenching, t h a n on cold days and t h a t herein lay most of the trouble. So he said to Mr. Nash, " I f you will just use pyrometers to tell what the temperature really is instead of guessing, your troubles will be over." Mr. Nash saw t h a t this was so and thanked Ket for the suggestion. Ket said, "All right Charley, I learned t h a t in our lab- oratory and now I want t h a t dollar." And Mr. Nash signed the contract. Q. Doctor, how does what you have been telling us apply to an every day article such as a refrigerator? How does science in industry apply to the refrigerator itself? A. Well, in the first place, no savage has the slightest conception t h a t he possesses the ability to make things cold b y applying power b u t with the development of the science of thermodynamics. Q. Well, Doctor, t h a t sounds like a $64 word. A. Yes, all of that, as I was saying with the development of this science, it became quite clear to one versed in this science t h a t a machine like the engine of James W a t t made to run backwards in principle could absorb power and pump heat out of things which is all one needs to do to make things cold. This is refrigeration. The household refrigerator is the embodiment of this scientific idea. Q. Is then air conditioning nothing more or less than a glorified refrigerator ? A. In a sense, yes, but had t h a t been all there was to it, the cooled dining car t h a t ran from Columbus to Cincinnati in the 1860's would have been a success. Unfor- tunately, its designer knew nothing about humidity nor how unpleasant a person could be in air so humid t h a t his perspiration would not dry. I t was over half a century later before science understood these simple facts so t h a t refrigeration could be expanded to give comfort in hot weather which is a simple definition of air conditioning. But even this was not quite enough. Reversing the principle of W a t t ' s steam engine is not enough. Steam doesn't work well backwards. One has to use a substance with properties quite different than water to get results in refrigeration. In the early days of artificial ice making, ammonia gas was used exclusively as the refrigerant. Later with the advent of household units, SO2 became very popular, also methylchloride. One trouble of applying such things to air conditioning was t h a t if there was a leak, even a small one, people's lives were in danger. A new refrigerant was needed—one t h a t was neither toxic nor combustible. Mr. Kettering saw t h a t such a substance was essential to the development of air conditioning. So, one morning, he called me up and told me to get to work on this problem. With the aid of Dr. A. L. Henne the problem was solved b y using dichlorodifluoromethane. N o . 4 RADIO ADDRESS : SCIENCE AND INDUSTRY 163 Q. I think that one should be worth $65. A. Well, Paul, as a matter of fact, it turned out to be worth many millions and gave comfort to many millions more. So that today by the application of science to the improvement of refrigerants, a brand new industry came into existence, and air conditioning in theaters, restaurants, railroad cars, stores, office buildings, is well nigh universal. However, it has been terribly disappointing to see the Amer- ican public fail to make more use of it in their homes. It is my feeling that had we been willing to raise our standard of living to the air conditioned level during the early 30's much of the depression unemployment could have been avoided. Q. All right Dr. Midgley, you have explained the application of science to the common refrigerator. Now let me ask you how some lesser known science, such as say Entomology or bug study, can be applied to industry? A. I see you too started on the $64 words. Q. Doctor, I think it's catching. A. As a matter of fact, Entomology has not played a very important part in what we call industry. Maybe we use some exterminators in the woolen goods industry and maybe we don't. I don't know. Yet if we look at the whole, Entomology is important. Many insect pests must be eradicated or at least controlled for suc- cessful farming. This is done largely by the use of chemicals called insecticides which constitute a fair portion of our normal peacetime production of chemical goods. Q. Well, that answers my question, Doctor, and now getting back to the factory, what has science done towards the fabrication of metals, the making of steels and alloys? How does science work here? A. Suppose we start at the beginning. Primitive man was unacquainted with the properties of metals. It is supposed that some ancient person used some sort of copper ore to blanket a fire. Later he discovered some particles of copper in the ashes and observed that here was a stone which could be fashioned by ham- mering and hence he could make arrowheads, knives and the like which were better than the chipstone implements he had been used to and so it went. Individual discoveries passed on from generation to generation building up a craft of metal work. For example, take the much vaunted steel of Damascus. Was this the result of science? No. Damascus steel actually was one of the poorest steels known to the ancient world. It was too hard and brittle for practical use so the blacksmiths of Damascus took small rods of steel and small rods of wrought iron, wound these together and hammered them into a single rod. These rods in turn were twined with others and the whole welded together by hard work. The result was a sword or a knife that could be sharpened to a razor edge and was held together by the tough wrought iron. No one else could make as good a sword. Today we would take the brittle steel of Damascus, analyze it, probably find too much phosphorous, add what would be needed to remove the phosphorous, in the furnace operation add some nickel, tungsten and vanadium and without any blacksmithing turn out knives, swords or razor blades that would make any Damascan green with envy. This is science. Q. Using scientific methods, what have been some of the modern day develop- ments in the fabrication of metals? A. Well, you might call the railroad one, the Golden Gate Bridge another, the three hundred mile an hour airplane one more, telephone communication still another and so on ad infinitum. Q. Along with steel, Dr. Midgley, rubber has contributed much to modern living standards. Where does science enter into the making of rubber? A. It is said that Christopher Columbus took back a piece of rubber on his first voyage and this was the first contact that white men had with this very valuable material. Be that as it may, rubber was not of much value until Charles Goodyear 164 N. PAUL HUDSON Vol. X L I I by applying research methods, discovered that rubber would combine with sulphur to give the remarkable resulting product with which we are all familiar. This was about a century ago. Since then other scientists, principally chemists, have added to the knowledge of and the utility of this material. The importance of vulcanized rubber to modern life cannot be over-emphasized. Without it we would have no automobiles, no electrical industry, no air brakes, no golf balls or airplanes, suspend- ers or erasers, faucet valves or garden hose. All of which depend upon this product of science. Again to emphasize its value, the Kaiser did not start the war in 1914 until his advisors told him that Germany could make synthetic rubber. They were wrong and Germany lost. Hitler made more certain. Today Germany supplies its own needs of synthetic rubber; product of science. We, on the other hand, have been a bit backward. Our hope is now that our scientists will catch up. Q. What would you say, Dr. Midgley, in summing up the role of science in industry ? A. Industry is science. The two are inseparable, Siamese twins, except that some science would go on without industry but no industry could live long without science. Management which neglects science is neglecting its business and failure will be the ultimate reward. New applications of science mean success and it will always be so. work_booke56jtvdxdnzapuy25wserq ---- UCL Discovery Close UCL Home Prospective students Current students Staff UCL Discovery Home A nascent retina, generated from a 3D embryonic stem cell culture Home Main navigation items Lists can be nested Lists can be nested Main navigation items Home Students Staff NHS Visitors Electronic resources Libraries and study spaces Opening hours Open Access Research Data Management Bibliometrics Special Collections, Archives & Exhibitions Getting help & contacting us About us Home Main navigation items Main navigation items Home Home IOE EPrints Notice IOE EPrints is now part of UCL Discovery. Your page will load within 5 seconds. If your page does not load, please click here. Sidebar Supporting content, patterns or related links can be placed in the sidebar Facilities Faculties and departments Library Museums and Collections UCL Bloomsbury Theatre Maps and buildings Locations UCL and London UCL Australia UCL Qatar UCL Global Connect with us Alumni Businesses Media Relations Jobs Give to UCL University College London, Gower Street, London, WC1E 6BT Tel: +44 (0) 20 7679 2000 Copyright © 2015 UCL Disclaimer Freedom of Information Accessibility Privacy Cookies Contact Us work_bpqhdcbvyzbzhasz3jjh3jtrkq ---- 150 D E B A T E 1 Keywords Resistance Monuments History Protests Debate should monuments resist? The social outbreak of October 2019 defined a new role for monuments in Chile. During the demonstrations, not only the statues that paid tribute to Spanish conquistadors – namely, those who built a country to the detriment of the native peoples – were torn down, but the historical (therefore constructed) backing of certain buildings’ patrimonial status was also questioned. Even the Baquedano monument, located in the middle of a roundabout of the same name, at the focal center of the demonstrations in Santiago, was completely covered with new meanings during the protests. A R Q 1 0 5 — S A N T IA G O , C H IL E 151 2 In late May 2020, the death of African American citizen George Floyd – at the hands of the Minneapolis police, in the U s – reactivated the Black Lives Matter movement, which resists and opposes racism against African American people. In the context of this movement, a series of statues that paid tribute to slave-traders and owners were attacked, generating a surprising parallel (just months away), between what happened in Chile and in other parts of the world. Considering both events, in the debate on this issue of a r Q we asked: should monuments resist in place? Or is it preferable to protect them by removing them from the public space? What happens if their meaning changes? Are they still considered monuments? What is it that resists in them? After all, if monuments materialize the intersection between history, architecture, and the city, what can resist the most, their meaning or their material? FIG. 1 La estatua de Edward Colston cae en Bristol, Inglaterra, el 7 de junio de 2020. Edward Colston Statue falls in Bristol, England, on June 7, 2020. © Ben Birchall, Pa Wire/ Pa Image FIG. 2 Estatua del General Baquedano después de las protestas del estallido social iniciadas el 18 de octubre de 2019, Santiago de Chile. The General Baquedano Statue after the protests of the social outbreak, which started on October 18, 2019, Santiago, Chile. © Francisco Díaz, 23 de febrero de 2020 / February 23, 2020 152 D E B A T E Continúa en / Continues in: p. 154 I n 1936, Robert Musil famously wrote: “there is nothing more invisible than a monument.” Nothing seems further from the truth right now. In Bristol, protesters recently tossed a statue of slave trader Edward Colston into the harbor; in Antwerp, activists are defacing bronzes of King Leopold II; in the United States, citizens are toppling Confederate monuments; and across the world statues of Christopher Columbus are falling. The toppled, sunken, defaced, vandalized and beheaded statues of these past months speak to the reemergence of rage and discontent against monuments – Confederate, federal, patriarchal, colonial, racist, white –, spatial reminders of structural and representational inequality. The recent protests against racism in the United States and across the world reveal a special affinity between monuments and social protests; between citizens occupying the streets to demand justice and the dead bronzes standing in their way. The same can be said about the social upheaval that started in response to a public transportation fare hike in Chile on October 18, 2019. During months of massive protests for equality, justice and redistribution, Chilean demonstrators toppled, beheaded and vandalized monuments honoring Spanish colonizers and Republican war heroes who sought to eradicate native peoples. Our current statuophobia is different from that of the 20th century counter-monument movement reflected in Musil’s words, as well as the 19th century monument disdain. While monuments’ lack of function upset modernists, the growing number of new unregulated monuments troubled city planners a century before. Today we are grappling with a different kind of monument malaise: our monuments no longer reflect who we are. The problem is twofold. For the one part, cities have largely failed to build monuments to represent current – or rather – aspirational values: monuments to black lives, to women, to the lG B tq + community, to minorities, to people of color, to immigrants, to the disabled, and to ordinary citizens. For the other part, cities have been reluctant to remove offensive, racist and colonial monuments of the past. In Berlin, for example, Black and Afro-German activists and their allies have been struggling for over a decade to remove colonial and racist street-names from the city center and to build a memorial to the victims of German colonialism. Similarly, it took 23 years after the return to democracy, for a central throughway in Santiago de Chile honoring September 11, the date of the military coup, to be renamed. Most of the monuments that have been toppled in the past few weeks, were removed by Sinking Monuments: Notes on our Current Statuophobia Va L e n t i n a r oz a s - K r au s e Becaria postdoctoral y profesora adjunta, University of Michigan, Ann Arbor, Estados Unidos 154 D E B A T E activists and protesters. One of the only exceptions is the Columbus statue in San Francisco, which the city removed preemptively as a form of preservation. While protesters’ actions might seem violent, they are a response to decades of veiled and overt racism and indifference combined to perpetuate the monumental status quo. In other words, without protests, much of the Robert E. Lee, Leopold II, and Columbus statues of the world would remain intact, protected by a veil of selective invisibility. In response to our present-day statuophobia most monument supporters claim that removing monuments is an erasure of history. This widely echoed argument not only conflates history with its representation, but also assumes that all monuments were erected with the purpose of preserving the memory of a deed, event, or figure of the past. Both assumptions are false. While monuments might tell stories, they are not stone and bronze versions of peer-reviewed history books. On the contrary, monuments are the result of selection and erasure processes, strongly aimed at maintaining dominant narratives. Every statue is the product of a specific cultural and political milieu that decided to elevate a certain version of the past over multiple others. The proliferation of Confederate monuments erected after the end of the American Civil War to spread the false narrative of the ‘Lost Cause’ illustrates this point. These Confederate statues are not historical monuments, but purposefully ahistorical representations of the past. History at large is not in danger, what has been threatened by the recent removal of monuments is a certain version of the past, one that justified colonialism, genocide, slavery and injustice in the name of ‘progress and enlightenment.’ As cities across the world grapple with the monument debris of the ongoing protests against racism and police brutality, I would like to conclude with one photograph (F i G . 1). The photograph of the bronze of Edward Colston being tossed into the Avon river, which was located later in the middle of Bristol harbor by the witty Google Maps algorithm. Colston, like most of his kind, was rescued from the bottom of the river and stored in an undisclosed location. Museums have been our preferred place for defunct objects of the past. However, I would argue that under our current circumstances there are other alternatives to consider besides exhibiting these monuments in an enclosed and regulated space. Perhaps some monuments should be left untouched – showing the accumulative signs of vandalism and re-appropriation, perhaps others could be put in dialogue with new monuments that reframe their values, and perhaps some statues deserve to stay underwater. ARQ Valentina Rozas-Krause Architect and Master in Urban Planning, Pontificia Universidad Católica de Chile. PhD in Architecture, University of California, Berkeley. She is currently working on her next book Memorials and the Cult of Apology as a postdoctoral Collegiate Fellow at the University of Michigan. work_btbxnlynsva6ddi2crpb6kuo6e ---- R. Price S. Price Sancocho In: New West Indian Guide/ Nieuwe West-Indische Gids 69 (1995), no: 1/2, Leiden, 127-141 This PDF-file was downloaded from http://www.kitlv-journals.nl Downloaded from Brill.com04/06/2021 01:09:22AM via free access RlCHARD & SALLY PRICE SANCOCHO In devoting this essay to sancocho, we continue our tradition of annual book round-ups spiced with Caribbean culinary lore. Having already served up pepperpot and rundown from the Anglophone islands, migan from Martinique and Guadeloupe, and callaloo from all of the above, the time seemed ripe to turn to the Hispanic Caribbean. And as our list of books has expanded (from the forty to fifty of previous years to nearly one hundred in this installment), a dish with as many ingredients as sancocho seemed particularly appropriate. According to Manuel Vargas, who generously shared with us his ample knowledge of sancocho in the Dominican Republic, the ideal is to include seven meats (pork, beef, goat, chicken, turkey, duck, and pigeon) as well as "many spices and as many roots and vegetables as possible." Ligia Espinal de Hoetink's more detailed recipe, also from the Dominican Republic, includes longaniza sausage, chicken, pork chops, salt pork, and goat meat, as well as pumpkin, plantains, corn-on-the-cob, four root crops, vinegar, and a variety of herbs, vegetables, and broths. Our Man in San Juan, Antonio Dfaz-Royo, provided a number of Puerto Rican recipes from both literary and domestic sources, even treading in the perilous waters of mother-daughter rivalry by eliciting versions from his wife, Cruz Nazario, and her mother, Dofla Sol (whose reaction to her daughter's recipe, presented anonymously by her diplomatic son-in-law, was to dismiss it as mere sopón). Despite variation on some of the details (notably celery, chickpeas, and sofrito), they both confïrmed the general heart of the dish - several different meats and root crops, plus plantains, pumpkin, and corn-on-the-cob. There are also regional differences; Vargas reports that in the Dominican Republic, for example, wheat-flour dumplings are used in the east but pigeon peas are more common in the north and southwest. Downloaded from Brill.com04/06/2021 01:09:22AM via free access 128 New West Indian GuidelNieuwe West-Indische Gids vol. 69 no. 1 & 2 (1995) Elisabeth Lambert Ortiz's Complete Book of Caribbean Cooking (1973) offers seven sancocho recipes, all from the Dominican Republic, plus a saucochi di gallinja from Aruba (whose ingredients include beef, veal, chicken, potatoes, sweet potatoes, pumpkin, corn-on-the-cob, plan- tains, and more) and a Trinidadian dish called sancoche, which adds coco- nut cream and cornmeal dumplings to the usual list of ingredients. Trinidadian sancoche is documented without the cornmeal dumplings in Callaloo, Calypso & Carnival: The Cuisines of Trinidad and Tobago (see NWIG 68:130); it has also been described as a Saturday dish that simply cooks up all the week's leftovers (meat, coocoo, rice, fish, etc.) in a single pot (Gerard Pantin, A Mole Cricket Called Servol, Ypsilanti MI: High/Scope Press, 1979:115) - a concept that strikes us as particularly analogous to the mixed pot of otherwise-unreviewed books we present in the following pages. We have been told that sancocho is also found in Colombia and Venezuela. Putting theory into practice while writing this essay, we served up our own seven-meat sancocho at a pre-Christmas party. Our Martiniquan guests suggested that the closest local equivalent, in this ever racially- conscious society, might be manjé-milat ("mulatto meal"), which is made with "half chicken and half pork, half plantains and half root crops." As part of the same discussion, poet Nancy Morejón, in Martinique to serve on the jury for the Prix Carbet des Caraïtes (awarded this year to Raphaël Confiant, see below) reported that there's nothing called sancocho in her native Cuba but that qjiaco comes very close. Indeed, one printed source (the upper-class Memories of a Cuban Kitchen - see NWIG 68:130) offers an ajiaco criollo that includes three kinds of beef, green and ripe plan- tains, corn-on-the-cob, pumpkin, five root crops, and a sofrito. All of our consultants say that sliced avocados are a customary side dish, all mention rainy days as particularly appropriate for sancocho- eating, and all link the stew to rural, rather than urban, settings (though Harry Hoetink encouraged an open attitude toward contexts, citing an ex- ceptionally good sancocho that he and Ligia once stumbled upon in a shopping-mall restaurant in Kissimmee, Florida). While our two main Dominican authorities differed on whether the dish should be enjoyed with rum or beer, both cited the classic merengue, "El sancocho prieto." Manuel Vargas provided the full lyrics (by Julio Alberti) to support his argument about the strong sexual connotations of the dish: Downloaded from Brill.com04/06/2021 01:09:22AM via free access REVIEW ARTICLES 129 Del sancocho prieto Some black sancocho, color de tu carne, with meat of your color, til tendras que darme, you'11 have to give me porque estoy hambriento. because Fm very hungry. Del sancocho dame, Give me some sancocho tambien de tu amor. as well as your love. Quiero con ardor I want passionately yo saciar el hambre. to satisfy my hunger. El humo de la paila The smoke from the kettle quema tan caliente is burning as hot como quema tu alma. as your soul is burning. Dentro la gallina Inside, the chicken sabe tan sabrosa como tü tastes as sweet as you, hermosa, sabes a divina. my beauty, who tastes divine. There's much more to the story, in terms of such considerations as race, class, and gender. But we have many books to review, and must move on. We begin, as usual, with our Caribbeanist Hall of Shame, listing those books that (as of press time, January 1995) we have been unable to review because the scholars who agreed to the task (identified here by initials in square brackets) have - despite reminder letters - neither provided a review nor returned the books so that they could be assigned to someone else. As in the past, this paragraph may serve as a kind of backlist "books received." (And as always, we would still welcome the submission of any of these reviews, however tardy.) The Atlantic Slave Trade: Effects on Economies, Societies, and Peoples in Africa, the Americas, and Europe, edited by Joseph E. Inikori & Stanley L. Engerman (Durham: Duke University Press, 1992, cloth US$45.00, paper US$17.95) [J.C.C.]; Ideology and Class Conflict in Jamaica: The Politics of Rebellion, by Abigail B. Bakan (Montreal: McGill-Queen's University Press, 1990, cloth US$ 39.95) [D.A.-B.]; The Meaning of Freedom: Economies, Politics, and Culture after Slavery, edited by Frank McGlynn & Seymour Drescher (Pittsburgh: University of Pittsburgh Press, 1992, cloth US$ 49.95, paper US$ 19.95) [L.R.]; Whispers from the Caribbean: 1 Going Away, I Going Home, by Wilfred Cartey (Los Angeles: Center for Afro-American Studies, UCLA, 1991, paper US$ 43.00) [M.McW.]; The Islands and the Sea: Five Centuries of Nature Writing from the Caribbean, edited by John A. Murray (New York: Oxford University Press, 1991, cloth US$ 22.95) Downloaded from Brill.com04/06/2021 01:09:22AM via free access 130 New West Indian GuidelNieuwe West-Indische Gids vol. 69 no. 1 & 2 (1995) [D.W.]; El Caribe hacia el 2000, edited by Andrés Serbin & Anthony Bryan (Editorial Nueva Sociedad, 1991, paper n.p.), jVecinos indiferen- tes? El Caribe de habla inglesa y America Latina, edited by Andrés Serbin & Anthony Bryan (Caracas: Editorial Nueva Sociedad, 1990, paper n.p.) and El Caribe entre Europa y America: Evolución y perspectivas, edited by Luis Beltran & Andrés Serbin (Caracas: Editorial Nueva Sociedad, 1992, paper n.p.) [C.A.R.]; Haiti and the United States: The Psychological Moment, by Brenda Gayle Plummer (Athens: University of Georgia Press, 1992, paper US$ 18.50, cloth US$ 45.00) [K.R]; Sojourners in the Sun: Scottish Migrants in Jamaica and the Chesapeake, 1740- 1800, by Alan L. Karras (Ithaca: Cornell University Press, 1992, cloth US$ 34.50) [R.A.McD.]; Surinaams contrast: Roofbouw en overleven in een Caraïbische plantagekolonie 1750-1863, by Alex van Stipriaan (Leiden: KITLV, 1993, paper NLG 60.00) [R.B.-S.]; Peregrinos de la libertad: Documentos y fotos de exilados puertorriquenos del siglo XIX localizados en los archivos y bibliotecas de Cuba, by Félix Ojeda Reyes (San Juan: Editorial de la Universidad de Puerto Rico, 1992, cloth US$ 29.95) [J.L.D.]; The Suffer ing Grass: Superpowers and Regional Conflict in Southern Africa and the Caribbean, edited by Thomas G. Weiss & James G. Blight (Boulder CO: Lynne Rienner, 1992, cloth US$ 30.00) and The Russians Aren't Coming: New Soviet Policy in Latin America, edited by Wayne S. Smith (Boulder CO: Lynne Rienner, 1991, cloth US$ 25.00) [A.S.]; Identifying Crime Correlates in a Developing Society: A Study of Socio-Economic and Socio-Demographic Contribu- tions to Crime in Jamaica, 1950-1984, by Hyacinthe Ellis (New York: Peter Lang, 1991, cloth US$ 49.95) [J.E.]; The Novels ofV.S. Naipaul: A Study in Themes and Form, by Shashi Kamra (New Delhi: Prestige, 1990, cloth Rs. 180) and On the Margins: The Art of Exile in V.S. Naipaul, by Timothy F. Weiss (Amherst: University of Massachusetts Press, 1992, cloth US$ 30.00) [S.N.]; Esclaves et citoyens: Les noirs a la Guadeloupe au XlXe siècle dans les processus de resistance et d'intégration (1802- 1910), by Josette Fallope (Basse-Terre Guadeloupe: Société d'Histoire de la Guadeloupe, 1992, paper n.p.) [D.T.]; Sources of Bahamian History, edited by Philip Cash, Shirley Gordon & Gail Saunders (London: Macmillan Caribbean, 1991, paper £6.95) and Supplement to A Guide to Source Materials for the Study of Barbados History, 1627-1834, by Jerome S. Handler (Providence RI: The John Carter Brown Library and The Barbados Museum and Historical Society, 1991, cloth US$ 22.50) [H.J.]; The Jamaican Stage, 1655-1900: Profile of a Colonial Theatre, by Errol Hill (Amherst: University of Massachusetts Press, 1992, cloth US$ 35.00) [L.F.]; Ex-iles: Essays on Caribbean Cinema, edited by Mbye Downloaded from Brill.com04/06/2021 01:09:22AM via free access REVIEW ARTICLES 131 Cham (Trenton NJ: Africa World Press, 1992, cloth US$ 49.95, paper US$ 18.95) [K.A.]; The Caribbean in the Pacific Century: Prospects for Caribbean-Pacific Cooperation, by Jacqueline A. Braveboy-Wagner, with W. Marvin Will, Dennis J. Gayle & Ivelaw L. Griffith (Boulder CO: Lynne Rienner, 1993, cloth US$ 35.00) and Pursuing Postdependency Politics: South-South Relations in the Caribbean, by H. Michael Erisman (Boulder CO: Lynne Rienner, 1993, cloth US$ 30.00) [R.P.]; Les repré- sentations du corps chez les noirs marrons ndjuka du Surinam et de la Guyanefrangaise, by Diane Vernon (Paris: ORSTOM, 1992, n.p.) [D.N'D.]; Sam Selvon's Dialectical Style and Fictional Strategy, by Clement H. Wyke (Vancouver: University of British Columbia Press, 1991, cloth US$ 35.95) [V.R.]; The C.L.R. James Reader, edited by Anna Grimshaw (Oxford: Blackwell, 1992, cloth £45.00, paper £12.95) [B.S.]. And finally, none of the several Césaire specialists we asked to review Aimé Césaire, by Janis L. Pallister (New York: Twayne, 1991, cloth US$ 24.95), feit it worthy of their attention. Although as a matter of policy the NWIG does not review literature, we continue the tradition of briefly noting those new works that we have seen in the last twelve months. First, two contrasting novels. V.S. Naipaul's A Way in the World: A Novel (New York: Knopf, 1994, cloth US$ 23.00) covers vast territories of the imagination, from the precise, almost surgical memoirs of his summer-before-leaving-for-England as an assistant clerk in the Red House, to morose wanderings and dreamings near the mouth of the Orinoco, contemplating El Dorado - all themes he has plumbed before, yet once again with that inimitable stylistic finesse and chilling gaze. With Stedman and Joanna - A Love in Bondage: Dedicated Love in the Eighteenth Century (New York: Vantage, 1991, cloth US$ 15.95), Beryl Gilroy offers an apparently well-meaning (vanity- press) historical novel that hovers between the maudlin and the ridiculous; though the author has previously produced respectable fiction, this work can only be read as an embarrassment even by someone unfamiliar with Stedman's original, which needs no bowdlerization. An unusual number of first novels have appeared. Dreaming in Cuban, by Cristina Garcia (New York: Knopf, 1992, cloth US$ 20.00), moves back and forth, with panache and pathos, between Havana and Brooklyn, international and domestic politics, and the lives of four women. Secrets (New York: Villard, 1993, cloth US$ 20.00), by Trinidadian-born New York writer Keivin Christopher James, depicts in lyrical prose an island girl's coming of age. In Under the Silk Cotton Tree (Brooklyn NY: Interlink, 1993, paper US$9.95), Jean Buffong weaves richly-textured tales of village life in her native Grenada. Me Dying Trial, by Jamaican- Downloaded from Brill.com04/06/2021 01:09:22AM via free access 132 New West Indian Guide/Nieuwe West-Indische Gids vol. 69 no. 1 & 2 (1995) born Patricia Powell (Oxford: Heinemann, 1993, paper £5.99), provides a bitter-sweet perspective on the everyday realities of rural domestic life. The Roads Are Down (Oxford: Heinemann, 1993, paper £4.99), by Jamaican Vanessa Spence, engagingly explores the romance between a married American man and a young woman from the Blue Mountains. With Harriet's Daughter (Oxford: Heinemann, 1988, paper £5.99), the accomplished Tobagan-Canadian poet Mariene Nourbese Philip has published a book for children, dealing with such themes as migration, exile, and the inter-generational conflicts in adjusting to a multi-racial society. The Dispossessed, by Clem Maharaj (Oxford: Heinemann, 1992, paper £5.99), is an engagé exploration of the lives of the working poor on a Trinidad sugar estate. And Lawrence Scott's Witchbroom (Oxford: Heine- mann, 1993, paper £6.99) recounts, through an androgynous narrator, carnival tales interwoven with a visionary history of his native Trinidad. The latest erop of Francophone literature includes no fewer than three simultaneously-published works by Raphaël Confiant (complementing two major books he published the previous year): Bassin des Ouragans (Paris: Mille et Une Nuits, 1994, paper FF 10) is a mini-divertissement about contemporary Martinique; Commandeur du sucre (Paris: Ecriture, 1994, paper FF 120) offers a somewhat cardboard, didactic récit about 1930s life in and around the canefields; and the prize-winning L'Allee des Soupirs (Paris: Grasset, 1994, paper FF 130), depicts la vie foyalaise during the anti-colonial riots of 1959. Confiant's companion-in-créo/j/é, Patrick Chamoiseau, has written a sequel to his own Prix Carbet winner, Antan d'enfance (1990); set next to Lamming's classic In the Castle ofMy Skin, which covers similar ground, Chamoiseau's Chemin-d'école (Paris: Galli- mard, 1994, paper FF 80) seems cloyingly cute, adopting the third person (like the autobiographies of Charles de Gaulle and Julius Caesar) to depict the darling little négrillon, with an effect that is not unreminiscent of a highbrow bande dessinée. Finally, a very different sort of autobio- graphical work by the long-time rightist politician Victor Sablé, Mémoires d'un Foyalais, des iles d'Amériques aux bords de la Seine (Paris: Maisonneuve & Larose, 1993, paper FF 115), tries to settle old scores and offers a profoundly French-oriented, non-créoliste vision of Martinique. Four recent short-story collections have come in. A Boy Named Ossie: A Jamaican Childhood (Oxford: Heinemann, 1991, paper £4.95), by Earl McKenzie, is filled with simple tales of growing up in rural St Andrews. Mint Tea and Other Stories, by Jamaican Christine Craig (Oxford: Heinemann, 1993, paper £5.99), focuses on women's life on the island. The Man Who Loved Attending Funerals and Other Stories (Oxford: Heine- mann, 1993, paper £5.99) collects for the first time some of the Bajan Downloaded from Brill.com04/06/2021 01:09:22AM via free access REVIEW ARTICLES 133 stories by the late Frank Collymore, editor of Bim and godfather of the whole West Indian literary renaissance of the 1940s and 1950s. // So Happen (Oxford: Heinemann, 1991, paper £4.95) reissues the lively 1975 collection by the late Timothy Callender, from whom we once bought a novel he was hawking at the Barbados airport (How Music Came to the Ainchan People, 1979). Several major works of West Indian literature have been reprinted. The University of Michigan Press (Ann Arbor) has brought out George Lamming's 1954 novel, The Emigrants (1994, paper US$ 14.95), as well as a collection of his essays first published in 1960, The Pleasures ofExile (1992, cloth US$ 42.50, paper US$ 14.95), this latter with an insightful new foreword by Sandra Pouchet Paquet. The republication of Sam Selvon's Moses Migrating (Washington DC: Three Continents, 1992, cloth US$ 20.00, paper US$ 9.50) reminds us of the author's infectious and unpretentious enthusiasms - visiting Martinique from England just months before his death last year, he picked the very hottest kind of pepper from a bush in our garden and swallowed the better part of it, remarking that he hadn't eaten a fresh one since he'd last been in the West Indies. Roy Heath's The Armstrong Trilogy: From the Heat of the Day, One Generation, Genetha (New York: Persea, 1994, paper US$ 15.00) brings together three of this Guyanese novelist's best, collected here for the first time in one volume, as he intended. Duke University Press (Durham NC) has brought back into print C.L.R. James's classic memoir of colonialism, cricket, and growing up Trinidadian, Beyond a Boundary (1993, paper US$ 14.95). And the professorial team of William Breit & Kenneth G. Elzinga, who write under the name of Marshall Jevons, now boast a new edition of their 1978 mystery Murder at the Margin (Princeton NJ: Princeton University Press, 1993, cloth US$ 34.95, paper US$ 10.95), which uses (and from our Caribbeanist perspective, abuses) St. John as the platform for their lessons in economie rationality. Several literary works have appeared in translation. Maryse Condé's /, Tituba, Black Witch of Salem (Charlottesville: University Press of Virginia, 1992, cloth US$ 19.95) translates her 1986 imaginative account; an inter- view with the author following the text makes clear that her intent was to follow her intuitions about Puritan New England and Tituba's role in it rather than to write a "historical novel." Between Two Worlds (Oxford: Heinemann, 1992, paper £5.99) translates Simone Schwarz-Bart's second novel, Ti Jean L'horizon (1979), and Le Chainon Poétique (Champigny- sur-Marne: Edition L.C.J., 1994, paper n.p.) offers a selection of works by Cuban poet Nancy Morejón, in facing-page Spanish and French. And selected poems of Angel Cuadra, a Cuban (now-exile) of a very different Downloaded from Brill.com04/06/2021 01:09:22AM via free access 1 3 4 N e w West Indian Guide/Nieuwe West-Indische Gids vol. 69 n o . l & 2 (1995) stripe, are presented by Warren Hampton in Angel Cuadra: The Poet in Socialist Cuba (Gainesville: University Press of Florida, 1994, cloth US$ 19.95). A number of new collections of poetry have come to our attention. From Jamaica to New England, Lorna Goodison's Selected Poems (Ann Arbor: University of Michigan Press, 1992, cloth US$ 34.50, paper US$ 12.95) speaks in a rich and vibrant voice. Merle Collins's Rotten Pomerack (London: Virago, 1992, paper £5.99) moves rather between Grenada and London, and between longing to remember and trying to forget. Spring Cleaning (London: Virago, 1992, paper £5.99) is the most recent collection by Jean 'Binta' Breeze, the well-known Jamaican perfor- mance poet. And Duppy Jamboree and Other Jamaican Poems, by Valerie Bloom (Cambridge: Cambridge University Press, 1992, cloth £5.50, paper £3.75), consists of performance poems for children. Kamau Brathwaite has published two major poetic works. The Zea Mexican Diary (Madison: University of Wisconsin Press, 1993, cloth US$ 17.95) is a sustained, riveting account of his innermost thoughts during the three months when his wife Doris ("Mex") was dying of cancer in 1986 - written in his emerging "video" style. His richly-textured Barabajan Poems 1492-1992 (Kingston & New York: Savacou North, 1994, paper n.p.), presented in full-scale "video" on large-format pages, is filled with multiple surprises and humor. David Dabydeen's Turner: New & Selected Poems (London: Jonathan Cape, 1994, paper £7.00) presents his lyrical but muscular long poem, "Turner," taking off from that artist's luminous and horrific 1840 painting, "Slavers Throwing Overboard the Dead and Dying." Several books of essays deserve mention. Roots, by Kamau Brathwaite (Ann Arbor: University of Michigan Press, 1993, cloth US$ 32.50, paper US$ 14.95), reprints a collection first published by Casa de las Americas (Havana, 1986) gathering a number of EKB's major essays, including "History of the Voice." Motherlands: Black Women's Writing from Africa, the Caribbean and South Asia, edited by Susheila Nasta (New Brunswick NJ: Rutgers University Press, 1992, cloth US$ 36.00, paper US$ 12.95), brings together essays by a variety of astute critics. Pedro Pérez Sarduy & Jean Stubbs have introduced and edited the timely collection AfroCuba: An Anthology of Cuban Writing on Race, Politics and Culture (Melbourne Australia: Ocean Press, 1993, paper US$ 34.95). Anil Ramdas has published the second in his series of snappy T.V. interviews with non-Dutch intellectuals, In mijn vaders huis II (Amster- dam: Jan Mets, 1994, paper NLG 27.50), this time engaging among others Edward Said, Paul Gilroy, bell hooks, and Dick Hebdige. Downloaded from Brill.com04/06/2021 01:09:22AM via free access REVIEW ARTICLES 135 There are three new relevant volumes in the World Bibliographical Series, published at Oxford by Clio, and each containing some 600 an- notated items: Virgin Islands, compiled by Verna Penn Moll (1991, cloth US$ 78.00), which includes much useful material but inexplicably manages to overlook Gordon K. Lewis's The Virgin Islands: A Caribbean Lilliput (1972); St. Vincent and the Grenadines, compiled by Robert B. Potter (1992, cloth US$ 79.00); and Netherlands Antilles and Aruba, compiled by Kai Schoenhals (1993, cloth US$ 50.00), which suffers even more than the others from the series-wide targeting of mono-lingual Anglophone readers. The distinguished Haitianist Léon-Fran9ois Hoffmann has pro- duced Bibliographie des études littérair es haïtiennes 1804-1984 (Vanves: EDICEF, 1992, paper FF 120), an unannotated 2767-item-long list that makes a brave beginning in what are perhaps the Caribbean's most bibliographically troubled waters. Manuel J. CarvajaFs The Carib- bean 1975-1980: A Bibliography of Economie and Rural Development (Metuchen NJ: Scarecrow, 1993, cloth US$ 89.50) explains neither the jusüfication for (or significance of) its strict temporal limitations nor the rather random nature of its 5300 largely unannotated selections. Political Porties of the Americas and the Caribbean: A Reference Guide (Harlow Essex: Longman, 1992, cloth £82.00), edited by John Coggins & D.S. Lewis, provides encyclopedia-type data, including recent election results, updated to May 1992. A number of recent books devote one or more chapters to the Carib- bean. Size & Survival: The Politics of Security in the Caribbean and the Pacific (London: Cass, 1993, cloth £30.00), edited by Paul Sutton & Anthony Payne, includes Gary Brana-Shute's analysis of the Tukuyana Amazones insurgency in Suriname, Bishnu Ragoonath's assessment of the Abu Bakr coup in Trinidad, Ivelaw L. Griffith's overview of drug pene- tration in the Commonwealth Caribbean, and Paul Sutton's reflections on small state security in the region. Joseph K. Adjaye's edited book, Time in the Black Experience (Westport CT: Greenwood, 1994, cloth US$ 55.00), has a nuanced chapter by Kenneth M. Bilby about time and history among the Aluku Maroons as well as one by the volume's editor on the Maroons of Jamaica. Campesinos: Kleine boeren in Latijns-Amerika, vanaf 1520, edited by Arij Ouweneel (Amsterdam: Thela, 1993, paper NLG 49.50), gathers eighteen pieces by one American and several Dutch scholars including two on the Caribbean: Gert Oostindie's historical overview of Caribbean peasantries and Michiel Baud's analysis of nineteenth- and twentieth-century peasants in the Dominican Republic's Cibao region. Robert Durfee's Journal and Recollections of Newport, Rhode Mand, Freetown, Massachusetts, New York City & Long Island, Downloaded from Brill.com04/06/2021 01:09:22AM via free access 136 New West Indian Guide/Nieuwe West-Indische Gids vol. 69 no. 1 &2 (1995) Jamaica & Cuba, West Indies & Saint Simons Island, Georgia, ca. 1785- 1810, edited by Virginia Steele Wood (Marion MA: Belden Books, 1990, cloth US$ 29.95), contains a few pages on the Caribbean but the author's illness during this portion of the voyage limited his observations. For those still unsatiated by the Quincentenary, Rebecca Catz provides a Luso- centric perspective on the Great Navigator in Christopher Columbus and the Portuguese, 1476-1498 (Westport CT: Greenwood, 1993, cloth US$ 45.00). Alan Dundes's excellent and wide-ranging anthology, The Cockfight: A Casebook (Madison: University of Wisconsin Press, 1994, cloth US$ 58.00, paper US$ 19.95), includes a lone chapter on the Caribbean - Francis Affergan's idiosyncratic structuralist/psychoanalytic take on the Martiniquan variant. France's Overseas Frontier: Départe- ments et Territoires d'Outre-Mer (Cambridge: Cambridge University Press, 1992, cloth US$ 69.95), by Robert Aldrich & John Connell, competently skims through history, politics, and culture, serving as a useful English- language introduction to these "confetti of empire" - including Marti- nique, Guadeloupe, and Guyane. Jean Benoist's important work of medical anthropology, Anthropologie médicale en société créole (Paris: Presses Universitaires de France, 1993, paper FF 178), focuses on the fourth of France's vieilles colonies, Réunion in the Indian Ocean, but within an analytical framework of creolization that Caribbeanists would ignore at their peril. Finally, Creole Movements in the Francophone Orbit (special issue of International Journal of the Sociology ofLanguage, no. 102, 1993), edited by Ellen M. Schnepel & Lambert-Félix Prudent, includes several Caribbeanist chapters: on St. Lucia, Dominica, Haiti, Guadeloupe, and Martinique. A number of new editions or reprints of scholarly works merit mention. Prefaced by a new foreword by Faye V. Harrison, Comparative Perspec- tives on Slavery in New World Plantation Societies (New York: New York Academy of Sciences, 1993, cloth US$ 42.00), edited by Vera Rubin & Arthur Tuden, still contains much lively debate. A second edition has appeared of Sally Price's Co-Wives and Calabashes (Ann Arbor: Uni- versity of Michigan Press, 1993, paper US$ 14.50) with a new preface updating the situation of Maroon women and engaging some recent feminist controversies. The Puerto Ricans: A Documentary History, edited by Kal Wagenheim & Olga Jiménez de Wagenheim (Princeton: Markus Wiener, 1994, paper n.p), is a lightly revised edition of a 1973 collection. Unchanged reprints include: Bondsmen and Rebels: A Study of Master- Slave Relations in Antigua, by David Barry Gaspar (Durham NC: Duke University Press, 1993, paper US$ 18.95); Puerto Rico's Revolt for Independence: El Grito de Lor es, by Olga Jiménez de Wagenheim (Prince- Downloaded from Brill.com04/06/2021 01:09:22AM via free access REVIEW ARTICLES 137 ton: Markus Wiener, 1993, paper US$ 11.95); and A History of the Virgin Islands of the United States, by Isaac Dookhan (Kingston Jamaica: Canoe Press, 1994, paper J$ 494.00). Cuba: A Short History, edited by Leslie Bethel (Cambridge: Cambridge University Press, 1993, cloth US$ 44.95, paper US$ 14.95), reprints in handy form the country-specific chapters from the Cambridge History of Latin America (see NWIG 67:104). A Black Woman's Odyssey through Russia and Jamaica: The Narrative of Nancy Prince, introduced by Ronald G. Walters (New York: Markus Wiener, 1990, paper US$ 8.95), makes available this free African American's description of her 1840-41 stay in post-emancipation Jamaica. Puerto Rico: The Four-Storeyed Country and Other Essays, by José Luis Gonzalez (Princeton: Markus Wiener, 1993, paper US$ 12.95), translates for the first time these provocative essays on national identity by one of Puerto Rico's leading writers. And Reinier Heere, through his publishing house Lord & Hunter based on St. Maarten, has begun issuing a series of reprints on the history of the island; entitled Tropical Mirror, the series has thus far published relevant portions of M.D. Teenstra's De Neder- landsch West-Indische eilanden (1836/1837) as well as a 1937 article by F.S. Langemeyer in De West-Indische Gids, both translated into English. There are several new books of photography and a number on art, architecture, and gardening. The large-format Dancing on Fire: Photo- graphs from Haiti, by Maggie Steber with an introduction by Amy Wilentz (New York: Aperture, 1991, cloth n.p.) presents absolutely gripping color photos, taken between 1986 and 1991, arranged in a narrative sequence that underlines the horror and beauty - the despair and hope - of daily life during that period. In the stark, breathtaking Puerto Rico Mio: Four Decades of Change I Cuatro decadas de cambio (Washington D.C.: Smithsonian Institution Press, 1990, paper US$ 24.95) - which has introductory essays by, among others, Sidney W. Mintz and Arturo Morales Carrión - Jack Delano presents some 175 of the b/w photos (here printed as duotones) that he shot during the 1940s and 1980s, above all riveting images of working people and their families. Havana: Portrait of a City, by Juliet Barclay with photographs by Martin Charles (London: Cassell, 1993, cloth US$ 35.00) mainly portrays architectural monuments, to the end of the nineteenth century. Ute Stebich's A Haitian Celebration: Art and Culture (Milwaukee: Milwaukee Art Museum, 1992, paper n.p.) documents the fine collection recently acquired by the Milwaukee museum. The Art of Exclusion: Representing Blacks in the Nineteenth Century, by Albert Boime (Washington DC: Smithsonian Institution Press, 1990, paper US$ 24.95), conveniently presents a range of important and oft-neglected materials. Downloaded from Brill.com04/06/2021 01:09:22AM via free access 1 3 8 New West Indian Guide/Nieuwe West-Indische Gids vol. 69 n o . l & 2 (1995) The Caribbean: A Painter's Paradise, by William Wood (London: Macmillan Caribbean, 1993, cloth £9. 99), consists of this British author's own West Indian paintings, set off by fragments from the poems of Walcott, McKay, Drayton, and others. John Michael Vlach's handsome Back of the Big House: The Architecture of Plantation Slavery (Chapel Hill: University of North Carolina Press, 1993, cloth US$ 37.50, paper US$ 18.95) is devoted to the architecture of North American slave culture but contains pictures and insights relevant to all Caribbean historians. African-American Gardens and Yards in the Rural South, by Richard Westmacott (Knoxville: University of Tennessee Press, 1992, paper US$ 24.95), while again dealing with the southem United States, focuses on the present and provides ethnographers of the Caribbean numerous seeds for thought. Which leads us fairly naturally to Gardening in the Caribbean, by Iris Bannochie & Marilyn Light (London: Macmillan Caribbean, 1993, cloth £10.95) and Wild Plants of Barbados by Sean Carrington (London: Macmillan Caribbean, 1993, cloth £12.99), the first a how-to guide devoted largely to ornamental plants, and the second a useful illustrated compendium that describes more than five-hundred wild plants of all kinds. A bumper erop of guide books has reached us. Caribbean Ways: A Cultural Guide (Westwood MA: Riverdale, 1993, paper US$ 19.95), by the well-meaning Chelle Koster Walton, deliberately skirts the Club Meds and KFCs in "quest of an authentic [Caribbean] experience"; she gets much of it just about half right - in Jamaica, abengs become "cow-bells," in Martinique 1'Anse Mitan gets confused with 1'Anse a 1'Ane and Ie Frangois is canonized St. Fran9ois, the Guadeloupean drum called gwo ka turns into quo wa, and her garbled ideas on "language" (p. 218) are al- most worth quoting in extenso (though we won't). Rum & Reggae. The Insider's Guide to the Caribbean: What's Hot and What's Not, by Jonathan Runge (New York: Villard, 1993, paper US$ 17.00), which updates a 1988 St. Martin's Press publication, touts everything that Caribbean Ways eschews - "the best nude beaches," "the wildest yacht- ing nightlife scène," and ... you get the idea. Jamaica in Focus: A Guide to the People, Politics, and Culture, by Marcel Bayer (London: Latin America Bureau, 1993, paper £5.99), has nothing on hotels or beaches but provides an excellent introduction to social life and history - the sort of thing every island visitor should read. St. Vincent and the Grenadines, by Lesley Sutty (London: Macmillan Caribbean, 1993, paper £5.50), is a passable Baedeker by a veteran sailor and 20-year-long resident. There are two new texts for the Dutch market - Suriname (Landenreeks), by Wim Noordegraaf and Marie-Annet van Grunsven (Amsterdam: Koninklijk Downloaded from Brill.com04/06/2021 01:09:22AM via free access REVIEW ARTICLES 139 Instituut voor de Tropen, 1993, paper NLG 14.90), and Suriname, by Wim Noordegraaf (The Hague: ANWB, 1994, paper NLG 27.50) - the latter a detailed, practical guidebook for visitors to all parts of the country (including the new tourist-island developments in the Saramaka region where we worked), as well as to French Guiana and Guyana. A very different guidebook is Martinique (Paris: Gallimard, 1994, paper FF 175 - though bookstores on the island charge FF 204.75). Profusely illustrated with encyclopedia-style images (some as small as one cm2), written in part by university scholars, and covering with apparent expertise everything from plate tectonics and marine life to history and literature, this ambitious work nevertheless disappoints. It views ongoing cultural practices with a downward gaze, combining folklorization and museumification (with scarcely a word to let the reader know that Martinique's largest industry is tourism, which is wreaking great trans- formations throughout the isle). We are told, for example, in a handsomely illustrated two-page spread on the gomyé (the fishing boat dating back to the Caribs) that this craft "n'est plus utilisé actuellement que pour les courses traditionelles" - and yet as we sit at the laptop and look out at Anse Chaudière through a papaya tree, we can see one gomyé whose occupant is puiling fishpots, two others engaged in laying out a balaou seine, and a fourth making its way from the bourg of Anses d'Arlet toward Petite Anse. And the blatant appropriation of illustrations from foreign historical sources renders poor service to the text's arguments for Martinique's specificity. The authors give no indication, for example, that the Indien Caraïbe on page 76 is a Kalina from Suriname. Nor that the most important depictions of slave life are also lifted wholesale (and without credit) from Benoit's lithographs of that Dutch colony, embellished with a newly constnicted commentary implying that they show the particularities of Martinique - the text accompanying "slaves returning from the fields" (which Benoit titled "slaves on their way to the fields") points to the unusual elegance of their clothing; Benoit's "wigmaker with his young slave" is described here as wearing "the clothing of a freedman, proud that he need not carry anything himself'; the depiction of a slave fête, accompanied by a quote from Frantz Fanon, fails to mention that the image in fact shows the distinctive Surinamese doe; the entry on Ie costume ("In rags or nearly naked while working, the slaves liked to dress up, whenever they could, in fine clothing and jewelry") in fact shows typical nineteenth-century "missie" dress from Suriname; and even the vision of the heroic Maroon (here embedded in quotes from Césaire, Chamoiseau, Confiant, and Glissant) is illustrated by two uncredited images from Suriname - one a runaway slave and the other Downloaded from Brill.com04/06/2021 01:09:22AM via free access 140 New West Indian Guide/Nieuwe West-Indische Gids vol. 69 no. 1 & 2 (1995) a slave(!) that Benoit drew carrying a basket for nis master (who is here simply cropped out of the picture). This season's culinary harvest is sparse. Island Cooking: Recipes from the Caribbean (Freedom CA: Crossing Press, 1988, paper US$ 10.95) is a solid, unpretentious sampling from throughout the region, by the Jamaican-born Dunstan A. Harris. JnA Taste of the Tropics: Traditional & Innovative Cooking from the Pacific & Caribbean (Freedom CA: Crossing Press, 1991, paper US$ 10.95), Jay Solomon - an Ithaca NY restauranteur - does nis bit for globalization by providing a number of generic "island style" dishes and drinks. Cooking the Caribbean Way: A West Indies Recipe Book (St. Maarten: Lord & Hunter, n.d., n.p.) is a slap- dash affair replete with recipes missing key portions, historical howlers (e.g., that "peanuts were brought to the West Indies from Indonesia in 1890"), and the anonymous authors' "composite chef whom we call Celestine." Several new works on slavery and its aftermath. The Danish West Indian Slave Trade: Virgin Islands Perspectives, edited by George F. Tyson & Amold R. Highfield (St. Croix: Virgin Islands Humanities Council, 1994, paper n.p.), includes original contributions by Colin Palmer, Svend E. Holsoe, Sandra E. Greene, Karen Fog Olwig, and Highfield. The Kamina Folk: Slavery and Slave Life in the Danish West Indies, edited by George F. Tyson & Arnold R. Highfield (St. Thomas: Virgin Islands Humanities Council, 1994, paper n.p.), is a fine compilation of testimonies (many in translation) from first-hand observers. In "The Land is the Herit- age": Land and Community on St. John (St. John Oral History Asso- ciation, 1994, paper n.p.), Karen Fog Olwig offers a little gem consisting of oral testimonies combined with a moving analysis of the ways St. Johnians understand their own incorporation into the modern global system. Anthony de Verteuil, principal of St. Mary's College, continues nis series of high school-level, uplifting historical sagas with Seven Slaves and Slavery: Trinidad 1777-1838 (Port of Spain: Scrip-J Printers, 1992, paper n.p.). Some volumes didn't fit into our earlier categories. Alternative Cultures in the Caribbean: First International Conference of the Society of Caribbean Research, Berlin 1988, edited by Thomas Bremer & Ulrich Fleischmann (Frankfurt am Main: Vervuert, 1993, paper n.p.), includes a miscellany of papers, but as only some three of the twenty-three contributors are not German (or Austrian or Polish), the volume - which is largely in English with some French and Spanish - may be most useful as a window for non-German speakers on current Caribbeanist work across the Rhine. El Caribe colonial, by Consuelo Naranjo Orovio (Madrid: AKAL, Downloaded from Brill.com04/06/2021 01:09:22AM via free access REVIEW ARTICLES 141 1992, paper n.p.), part of a series of quincentennial pamphlets, makes a quick, encyclopedie run through the territory. Small Country Development and International Labor Flows: Experiences in the Caribbean, edited by Anthony P. Maingot (Boulder CO: Westview, 1991, paper n.p.) - for which we tried in vain to find a reviewer - contains a set of competent articles on the Anglophone islands, the Dominican Republic, and Haiti, that will be of interest to specialists. 'Bananensplit' in Europa: Protectionisme versus liberalisme in het Europese bananenbeleid, edited by C.P. van den Tempel & G.M. van der Horst (Amsterdam: Caribische Werkgroep AWIC, 1994, paper NLG 32.50), gathers together a number of pertinent reflections and statistics about the European banana market. Asuntos dominicanos en archivos ingleses, edited by Bernardo Vega & Emilio Cordero Michel (Santo Domingo: Fundación Cultural Dominicana, 1993, paper n.p.), translates into Spanish five English-language sources, including little-known archival manuscripts, on the Dominican Republic. And Gert Oostindie's Caraïbische dilemma's in een 'stagnerend' dekolonisatie-proces (Leiden: KITLV, 1994, paper NLG 12.50), the expanded version of his inaugural address on the occasion of taking up a professoral chair at Utrecht, ranges through time and space across the Caribbean world to home in, at the end, on present-day realities. Finally, and against all odds, the Bulletin du Bureau National d'Ethnologie (Port-au-Prince) has published a special issue, dated 1987- 1992, devoted in large part to "Ayti before and after 1492." RlCHARD & SALLY PRICE Anse Chaudière 97217 Anses d'Arlet, Martinique Downloaded from Brill.com04/06/2021 01:09:22AM via free access work_btqxzdn255fz5hqg6dqnmfmk6y ---- TJkEAMERICA5 A Quarterly Review of Inter-American Cultural History V o l u m e X J A N U A R Y , 1 9 5 4 Number 3 T H E DISCOVERY AND EXPLORATION O F T H E NICARAGUAN T R A N S - I S T H M I A N R O U T E , 1519-1545 Lyle N. McAlister 259 SILVIO R O M E R O AND T H E E V O L U T I O N OF LITERARY C R I T I C I S M I N B R A Z I L Alceu Amoroso Lima 277 A FRANCISCAN F I G H T E R FOR S O U T H A M E R I C A N I N D E P E N D E N C E : F R A Y L U I S B E L T R A N Fritz L. Hoffmann 289 J U A N D I A Z COVARRUBIAS: M E X I C O ' S M A R T Y R - N O V E L I S T / . S. Brushwood 301 S U R V E Y A T E N T A T I V E BIBLIOGRAPHY OF T H E S P A N I S H - L A N G U A G E P R E S S I N LOUISIANA, 1808-1871 .Raymond R. MacCurdy 307 D O C U M E N T S A F R E N C H T R A V E L E R I N M E X I C O I N 1768: T H E J O U R N E Y O F T H E V I C O M T E DE PAGES ( E d . ) Edwin A. Davis 331 I N T E R - A M E R I C A N N O T E S SESQUICENTENNIAL OF T H E C R E A T I O N OF T H E H A I T I A N N A T I O N A L FLAG Joseph F. Thorning 353 T w o N E W R E V I E W S OF I N T E R - A M E R I C A N I N T E R E S T 354 CHICAGO C U L T U R A L C E N T E R S B E G I N P H I L I P P I N E STUDIES PROGRAM 354 F O U R T H A N N U A L C O N F E R E N C E ON T H E CARIBBEAN 355 C H R I S T O P H E R C O L U M B U S AND A X A C A N A W A R D S P R E S E N T E D . . 356 M U S E U M O F INTERNATIONAL F O L K A R T DEDICATED I N SANTA F E 356 SERRA A W A R D OF T H E A M E R I C A S C O N F E R R E D ON C L A R E N C E H . H A R I N G 357 M I S C E L L A N E A 357 B O O K R E V I E W S 359 ACADEMY OF AMERICAN FRANCISCAN HISTORY The contents of T H E AMERICAS are fully indexed in the Catholic Periodical Index EDITORIAL STAFF FRANCIS B. STECK, O.F.M., Ph.D., Q u i n c y College. MAYNARD GEIGER, O.F.M., Ph.D., Mission Archivist, Santa Barbara, California. LAZARO LAMADRIO, O.F.M., Lic.Hist., W a s h i n g t o n , D . C. FIDEL CHAUVET, O.F.M., Ph.D., Mexico City, D . F . L I N O G . CANEDO, O.F.M., Ph.D., Washington, D . C. MICHAEL B. MCCLOSKEY, O.F.M., P h . D . Siena College. Assistant Managing Editor Acting Managing Editor, ad interim BEDE A . D A U P H I N E E , O.F.M., M.A., MICHAEL B. MCCLOSKEY, O.F.M., Ph.D. A c a d e m y of American Franciscan H i s t o r y . ADVISORY EDITORS GEORGE P . H A M M O N D , P h . D . University of California. ROBERT S. CHAMBERLAIN, Ph.D., Carnegie Institution of W a s h i n g t o n . CARLOS E . CASTANEDA, Ph.D., University of Texas. J O H N T A T E L A N N I N G , Ph.D., D u k e University. J. M A N U E L ESPINOSA, Ph.D., D e p a r t m e n t of State, W a s h i n g t o n , D . C FRANCE V . SCHOLES, Ph.D., University of N e w Mexico. DAVID R U B I O , O.S.A., Ph.D., Madrid, Spain. ENRIQUE CARLOS DE LA CASA, Ph.D., Secretary of t h e Inter-American Institute. M A N O E L CARDOZO, Ph.D., Oliveira Lima Library, Catholic University of America. RICHARD F . PATTEE, N a t i o n a l Catholic W e l f a r e Conference. L E W I S H A N K E , Ph.D., University of Texas. IRENE A . W R I G H T , F.R.H.S., D e p a r t m e n t of State, W a s h i n g t o n , D . C. L E O FRANCIS STOCK, Ph.D., Carnegie Institution of W a s h i n g t o n . R U T H L A P H A M BUTLER, Ph.D., N e w b e r r y L i b r a r y , Chicago. MARIE R. MADDEN, Ph.D., T e a c h e r s ' Institute of Brooklyn. ROSCOE R. H I L L , Ph.D., National Archives ( r e t i r e d ) . JOSEPH F . T H O R N I N G , Ph.D., Carrollton M a n o r , M d . W I L L I A M F . MONTAVON, LL.D., Director, Legal D e p a r t m e n t , National Catholic W e l f a r e Conference. H E N R Y GRATTAN D O Y L E , L i t t £ ) . , Dean, G e o r g e W a s h i n g t o n University. W . E U G E N E SHIELS, S.J., Ph.D., Xavier University, Cincinnati, O . Address all communications to T H E M A N A G I N G E D I T O R 5401 W . Cedar Lane W a s h i n g t o n 14, D . C. E n t e r e d as second class matter at the PostofEce at Washington, D . C , u n d e r t h e A c t of M a r c h 3, 1879. 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Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_bzd6qeaf2jak5kefekrqq37ngm ---- Underwater Cultural Heritage at Risk20 The Monte Cristi The Monte Cristi “Pipe Wreck” Jerome Lynn Hall Assistant Professor University of San Diego USA Background The Monte Cristi “Pipe Wreck” faces significant threats from both natural and human origins. The following is an outline of steps taken by the Monte Cristi Shipwreck Project (MCSP) in managing these impacts on this important site. The “Pipe Wreck,” so-called for the large quantity of clay, tobacco smoking pipes carried as cargo, was, until recently, one of the best known, yet least understood submerged cultural resources in the Dominican Republic. However, this is changing thanks to the generous support of several United States-based non-profit organizations, the University of San Diego (USD), and the dedication of the Oficina Nacional de Patrimonio Cultural Subacuático in Santo Domingo. The remains of this 17th-century merchantman are reshaping how we view colonial life in the Americas. The presence of intrusive artifacts on the site along with anecdotal evidence collected by the MCSP team combine to suggest that the “Pipe Wreck” has been salvaged many times over the past three and a half centuries. This is due, in large part, to its location in shallow, clear water less than a kilometer from the mainland. The geographical fact that the northern coast of Hispaniola is located in the seasonal hurricane corridor poses a threat to all submerged cultural resources in its shallow coastal waters, including the “Pipe Wreck.” Today, the expansion of the Monte Cristi suburbs and the development of a regional yacht club have resulted in an increasing number of tourist “day cruises” that pass within meters of — if not directly over — the site. Archaeological Investigation When archaeological excavation commenced in 1991, the visible portion of the site comprised scattered ballast stones, pipe stems, ceramics sherds, and concreted iron caldron fragments. Careful study of these artifacts by archaeologists and volunteers of the MCSP led to the formulation of research questions which, to date, have guided seven excavation seasons and several archival studies: Could the site be accurately, if not precisely, dated? Did the extant hull and cargo suggest a nation of origin? Could a specific vessel and journey be implicated? Why did the vessel sink in the shallow water of a protected bay? The investigation of these and other questions eventually led the team to hypothesize that the remains were of an inbound Dutch merchant vessel that wrecked between 1630 and 1665. Testing this idea entailed years of controlled excavation, historical research, and the subsequent conservation, analyses, and interpretation of numerous artifacts. As a result, researchers have revised the original date range, replacing it with a terminus post quem (date after which) of 1651 for the vessel’s demise and narrowing the temporal window from 35 to 14 years. The Artifacts The remnant cargo of the “Pipe Wreck” – not yet fully excavated – is certainly one of the largest and most diverse of any inbound merchantman destined for the Americas, rivaled only by Belle (1686), the “Quicksilver galleons” Conde de Tolosa and Nuestra Señora de Guadalupe (1724), and Machault (1760). Furthermore, a study of comparative contemporary sites suggests the vessel was headed for the eastern seaboard of what is presently the United States, specifically the Hudson River Valley, for its typically Dutch cargo compares well with archaeological collections from upstate New York, and specifically the Dutch-American settlement at Fort Orange (modern day Albany). The most conspicuous artifacts on the site are the pipes and pipe • • • • Figure 1: Yvonne Broeder, Monte Cristi Pipe Wreck team conservator, working at the dredge screen Underwater Cultural Heritage at Risk The Monte Cristi 21 demise of the ship: originally strung in hanks, these once spherical beads are now slumped and fused into each other, a phenomenon that occurs with intense heat lasting for a short period of time. Along with charred wood and melted metal globules, it appears that there may have been an explosion on board, a scenario that archaeologists are studying with considerable interest. Faunal remains indicate that sailors aboard the ship subsisted on a diet of beef, pork, salted fish, and conch. Occasionally, they competed with vermin for these foodstuffs, as evidenced by animal bones that bear rat incisor marks. Olive pits and other fruit stones appeared regularly in our dredge screens, indicating that the shipboard diet was indeed varied. The Ship Timber analysis indicates the vessel was constructed sometime after 1642. The manner in which it was built and the predominant wood types used in its construction suggest England as the locus of production. The extant keel, frames (N=17), outer planks (N=9), inner ceiling planks (N=6), and treenails were all shaped from English oak. Additionally, the hull was coated with tar and cow hair and covered with softwood deals (thin, protective outer boards) of spruce or larch, a measure common throughout the 17th-century to protect a ship’s hulls from biological degradation caused by teredo worms and bacteria. fragments, the combined collection of which represents the largest aggregation of smoking-related artifacts ever recovered from a shipwreck, and possibly from any known archaeological site. The pipes alone number close to ten thousand, yet only two distinct types are represented in this assemblage: those with barrel-shaped bowls – accounting for approximately 93% of the assemblage — and the remainder (7%) with bowls shaped like inverted cones, known as funnel pipes. All are of Dutch manufacture and date to the middle 17th-century, and although the former were preferred by Europeans and European-American colonists, funnel pipes are clear imitations of Native American designs and were intended for both the colonial and tribal trades. The wreck’s ceramic cargo is composed of Rhenish stoneware from Germany and two varieties of glazed earthenware that are likely Dutch in origin, all of which fit well into the aforementioned temporal framework. Fragments of Westerwald pottery, as well as green-glazed and orange- glazed wares were also recovered, but in such small quantities that they were likely ship’s wares rather than merchandise. Metal artifacts include numerous cooking cauldrons, an assortment of tools, lead shot, and 27 silver coins from two South American mints. Glass shards of many different colors have been found, but most interesting is a cluster of approximately 800 black glass beads. These, in fact, possibly hold a tantalizing clue to the Figure 2: Divers excavate and photograph the extant hull of the “Pipe Wreck” Underwater Cultural Heritage at Risk22 The Monte Cristi History Threatened, Yet Protected This research has confirmed the value of archaeological investigation in understanding the history and importance of the “Pipe Wreck”. Although not all of our research questions have been answered, these critical bits of information reveal a 17th-century merchant vessel that carried a cargo of European-manufactured trading goods, a part of which may have been for Native American tribes of the eastern seaboard of North America. Sailing during a period of volatile competition between the English and Dutch for maritime, mercantile, and military supremacy in both Europe and the Americas, our ship passed along the northern coast of Hispaniola, where historical sources suggest its crew may have engaged in illicit trade with smugglers. Likewise, there is strong evidence to suggest that this vessel entered the bay in search of salt, as today the outskirts of Monte Cristi are home to large, shallow evaporating pans. How far back this practice reaches is lost in the historical and ethnographic records, although Christopher Columbus noted at the close of the 15th-century that the region held great potential for salt production. To ensure that the archaeological value of the “Pipe Wreck” is protected against inclement weather and less-than- scrupulous tourists, its timbers have been buried beneath a protective covering of tarpaulins, sandbags, and a meter- thick layer of sand and coral rubble. The MCSP team continues to work diligently with local officials, fishing boat operators, and tourist guides to inform them of the importance of the “Pipe Wreck” to the regional history of the island’s northern coast, enlisting their cooperation in protecting one of the Dominican Republic’s most valuable cultural resources. Figures 3, 4 and 5 (Left to Right): Example of a smoking pipe from the wreck site(left); Rhenish stoneware from the “Pipe Wreck,” with the highly stylized Bartmänner, or bearded man face adorning the vessel’s neck (middle); and shoulder (right) work_c27tvcwfxjbzrklznhdhpawrg4 ---- Contributor Notes Contributor Notes Prairie Schooner, Volume 77, Number 1, Spring 2003, pp. 193-196 (Article) Published by University of Nebraska Press DOI: For additional information about this article [ This content has been declared free to read by the pubisher during the COVID-19 pandemic. ] https://doi.org/10.1353/psg.2003.0007 https://muse.jhu.edu/article/41648 https://doi.org/10.1353/psg.2003.0007 https://muse.jhu.edu/article/41648 CONTRIBUTOR NOTES cover “Head in the Sand” by Didier Delmas. Mr. Delmas’s photographs have been shown in galleries in Toulouse, France; Vancouver, B.C.; Washing- ton, D.C.; and throughout Vermont, where he resides with his wife, Nancy Welch. A portfolio of his commercial and artistic work can be seen at www.delmasdigital.com. Design by Dika Eckersley. prose Maxine Chernoff is author of three novels and three books of stories, most recently, Some of Her Friends That Year: New and Selected Stories (Coffee House P, 2002). She is editor with Paul Hoover of New American Writing. Lee Martin is author of the novel Quakertown (Dutton, 2001), the memoir From Our House (Dutton, 2000) and the story collection The Least You Need To Know. He is winner of a fellowship from the National Endowment for the Arts and the Mary McCarthy Prize in Short Fiction. Claudia Mon Pere’s fiction and poetry have appeared in The Kenyon Re- view, Puerto del Sol, Calyx, Another Chicago Magazine, and elsewhere. Rose Moss is author of The Family Reunion, The Terrorist and Shouting at the Crocodile. Her work has been short-listed for the National Book Award, won a Quill Prize and a PEN short fiction award, and was featured by the New Fiction Society. Ed Rutkowski is an editorial assistant with the Society for Technical Com- munication in Arlington, VA. Alex Shishin’s first story in Prairie Schooner, “Mr. Eggplant Goes Home,” received an Honorable Mention from the O. Henry Awards. His work has appeared in Broken Bridge: Expatriate Fiction from Japan and Shy Voice in American Literature. Sharon Oard Warner is author of Learning to Dance and Other Stories (New Rivers P, 1992) and Deep in the Heart (The Dial P, 2000), and editor of The Way We Write Now: Short Stories from the AIDS Crisis (Citadel P, 1995). She is the founding director of UNM’s Taos Summer Writers’ Conference. poetry Talvikki Ansel’s poetry collection My Shining Archipelago (Yale UP, 1997) won the Yale Series of Younger Poets Award in 1997. Her new book Jetty and Other Poems is forthcoming in 2003 from Zoo Press. Carol Willette Bachofner’s work has appeared in ELF: Eclectic Literary Form, My Home as I Remember, Gatherings: The En’owkin Journal of First North American Peoples (Vols. IX and XI) and Pacific Review. She won the Jack London Award for Poetry in 1997 and was named Wordcrafter of the Year in 1999 by the Wordcraft Circle of Native Writers and Storytellers. 03-N2536-CTB 1/24/03 9:18 AM Page 193 Todd Holmberg James Cihlar is the recipient of a Minnesota State Arts Board Fellowship in Poetry in 2000. His poems have appeared in The James White Review, Northeast, and Minnesota Monthly. Jim Daniels’s most recent book of poems is Night with Drive-by Shooting Stars (New Issues P, 2002). Michael Dumanis’s poems have appeared or are forthcoming in, Chel- sea, Crazyhorse, Epoch, Indiana Review, New England Review, Seneca Review, Verse, and other journals. He is the Poetry Editor of Gulf Coast. Joseph A. Enzweiler’s books include Home Country (Fireweed P, 1986), Stonework of the Sky (Graywolf P, 1995) and A Curb in Eden (Salmon P, 1999). Maria Mazziotti Gillan has published seven books of poetry, including Where I Come From (Guernica Editions, 1995) and Things My Mother Told Me (Guernica Editions, 1999), and is co-editor with her daughter Jennifer of three anthologies published by Penguin/Putnam: Unsettling America, Identity Lessons, and Growing Up Ethnic in America. She is the editor of The Paterson Literary Review. Ben Howard’s fifth poetry collection Dark Pool: Poems 1994 –2000 was published by Salmon Publishing in 2002. His work appears recently in The Sewanee Review and Shenandoah. Joseph Hutchison’s work appears in The American Poetry Review, Poetry, Luna, and Denver Quarterly. He is author of The Rain at Midnight (Sherman Asher P, 2000) and Bed of Coals (UP of Colorado, 1995), winner of the 1994 Colorado Poetry Award. Barbara Helfgott Hyett is the author of Natural Law (Summerland P, 1989), In Evidence (U Pittsburgh P, 1997), The Double Reckoning of Chris- topher Columbus (U Illinois P, 1992), and The Tracks We Leave (U Illinois P, 1996). Recent work appears in New Republic, The Hudson Review, Partisan Review, and elsewhere. Wayne Johns poems appear or are forthcoming in The Cortland Review, Image, Ploughshares and River Styx. He received a Prairie Schooner Reader’s Choice Award in 1999. Lynne Kuderko’s poems have appeared in Crab Orchard Review, Poetry Northwest, Indiana Review, Cimarron Review, Southern Poetry Review, Pas- sages North, and Luna. Her chapbook The Corner of Absence was published by Flume Press. George Looney is the author of Attendant Ghosts (Cleveland St UP, 2000) and Animals Housed in the Pleasures of the Flesh (Bluestem P, 1995), winner of the 1995 Bluestem Award. Tim Muren is a librarian’s assistant in Little Rock, Arkansas. Robert Phillips is author of thirty books of poetry, fiction, and criticism, most recently Spinach Days (2000) and Breakdown Lane (1994), poetry vol- umes from John Hopkins University Press. He is winner of an Award in Literature from the American Academy of Arts & Letters. David Ray’s books include The Tramp’s Cup (Chariton Review P, 1978), The 194 Prairie Schooner 03-N2536-CTB 1/24/03 9:18 AM Page 194 Touched Life (Scarecrow P, 1982), Sam’s Book (UP New England, 1994), Kan- garoo Paws (Truman St UP, 1994), Wool Highways (Helicon Nine Ed, 1993), and The Maharani’s New Wall (UP New England, 1990), as well as Fathers (St. Martin’s P, 1999), an anthology co-edited with his wife Judy. Two of his titles have won the William Carlos Williams Award from The Poetry Society of America, and two have been nominated for a Pulitzer Prize. His most recent book Demons in the Diner (Ashland Poetry P, 1999) won the Richard J. Snyder Memorial Award. Philip St. Clair’s fourth collection Acid Creek was published by Bottom Dog Press in 1997. His poems have appeared recently or are forthcoming in Black Warrior Review, Gettysburg Review, Ploughshares, Beloit Poetry Jour- nal and Chiron Review. He has been awarded fellowships from the National Endowment for the Arts (1995) and the Kentucky Arts Council (1999). Joan I. Siegel’s poetry appears recently or is forthcoming in The Atlantic Monthly, Commonweal, Yankee, The American Scholar, The Amicus Journal, and the anthologies Poetry Comes Up Where It Can, Beyond Lament, and Es- sential Love. She has won the New Letters Poetry Prize (1999) and the Anna Davidson Rosenberg Poetry Award (1998). Elisa Spindler’s poetry has appeared in Beloit Poetry Journal and New Letters. Maureen P. Stanton’s recent books are the poetry collection Glacier Wine (CMU P, 2001) and the short story collection Do Not For Sake Me, Oh My Darling (U Notre Dame, 2002). Marjorie Stelmach is author of Night Drawings (Helicon Nine Ed, 1995). Her work appears in The Kenyon Review, New Letters, Chelsea, and elsewhere. Judith Strasser’s poems appear recently in Poetry, Nimrod, 5 AM, The Se- attle Review, and The Underwood Review. Her chapbook Sand Island Succes- sions: Poems of the Apostles was published by Parallel Press in 2002. Joe Survant is the author of We Will All Be Changed (State St P, 1995), The Presence of Snow in the Tropics (Landmark Books, 2001), and Anne & Al- pheus, 1842 –1882 (U Arkansas P, 1995), winner of the Arkansas Poetry Prize in 1996. Kim Tedrow has published poetry in Cyphers 41 and interviews with John Barr and David Budbill in Grace and Moment to Moment respectively. Elaine Terranova is author of Damages (Copper Canyon P, 1996) and most recently The Dog’s Heart (Orchises P, 2002), and has new poems in Pleiades, Poet Lore, and Crab Orchard Review. She is associate editor for poetry at frigatezine.com. Kyoko Uchida’s work appears in The Georgia Review, Black Warrior Review, Grand Street, Manoa, New Letters, Northwest Review, Phoebe, The Virginia Quarterly Review, and elsewhere. Nance Van Winckel has poems recently in The Paris Review, The Virginia Quarterly Review, Field, The Kenyon Review, Michigan Quarterly Review, Massachusetts Review, The Gettysburg Review, and Ploughshares. Recent Contributor Notes 195 03-N2536-CTB 1/24/03 9:18 AM Page 195 books include the poetry collection After a Spell (Miami UP, 1998) and the story collection Curtain Creek Farm (Persea Books, 2000). She is the recipi- ent of an nea Poetry Fellowship. Pramila Venkateswaran was a finalist for the Allen Ginsberg Award. Her poems have appeared in Paterson Literary Review, Ariel, Calyx, Atlanta Re- view, Long Island Quarterly, and elsewhere. Paul Zarzyski is author of the books The Make-up of Ice (U Georgia P, 1984) and All This Way For the Short Ride (Museum of NM P, 1996) and the re- cording, Words Growing Wild (cd and tape). He makes his living primarily on the cowboy poetry circuit and has toured Australia and England and appeared at The Library of Congress, The National Storytelling Festival, and on Garrison Keillor’s A Prairie Home Companion. review Stephen C. Behrendt’s poems appear recently in Hudson Review, Sewanee Review, Ontario Review, and elsewhere. Elinor Benedict is founding editor of Passages North and author of All That Divides Us (Utah St UP, 2000), winner of the May Swenson Award. Jenny Factor’s first book of poetry is Unraveling at the Name (Copper Can- yon P, 2002). She teaches poetry at Beyond Baroque in Venice, California. Gaynell Gavin’s work has appeared in The Comstock Review, Natural Bridge, Tulane Review, and elsewhere. Anna Leahy’s poetry collection Hagioscope was winner of the Sow’s Ear Press Competition. Her poems have appeared in Crab Orchard Review, Im- age, The Journal, and Quarterly West. She is an assistant professor of En- glish at North Central College. Maureen P. Stanton’s work has appeared in Creative Nonfiction, The Sun, Fourth Genre, and American Literary Review, as well as several anthologies. 196 Prairie Schooner 03-N2536-CTB 1/24/03 9:18 AM Page 196 work_c2jfns2kcvgsxogitdm2y3wiwi ---- IJMM_Oct_08.indd www.ijmm.org Snippets Indian Journal of Medical Microbiology, (2008) 26(4): 409-10 RESEARCH SNIPPETS FROM THE WORLD OF MEDICINE P Desikan Intense public support for clinical research can be a mixed blessing � and the hunt for a vaccine against AIDS offers an important lesson for many biomedical initiatives on what can go wrong. Last year�s failed clinical trial for Merck�s HIV vaccine led many to claim that AIDS vaccine research was facing a crisis (Nature 452:503, April 2008). The decision to move Merck�s candidate vaccine into clinical trials was partly based on the need to show progress, in order to justify the millions of dollars in funding received from philanthropists and taxpayers. The vaccine not only failed to lower patients� viral loads, it even boosted the risk of infection in some groups. This dealt a double blow to the Þ eld of HIV research, leading to a setback in the search for therapies while eroding public support. In Africa, as elsewhere, fever is often treated presumptively as malaria, resulting in misdiagnosis and overuse of antimalarial drugs. In this scenario, rapid diagnostic tests (RDTs) for malaria may play an important role in improved fever management. A study carried out in Uganda (J Infect Dis. 15;197(4):510-8,2008) compared RDTs based on histidine-rich protein 2 (HRP2) and RDTs based on Plasmodium lactate dehydrogenase (pLDH) with expert microscopy and PCR-corrected microscopy for 7000 patients at sites of varying malaria transmission. HRP2- based RDTs were found to have high positive predictive and negative predictive values and were identiÞ ed as good diagnostic choices for areas with medium-to-high malaria transmission rates in Africa. Each of us carries a community of microorganisms in our intestinal tract that is necessary for optimal health but varies in composition from person to person. In order to identify gut microbes that maximally inß uence human physiology, a study was carried out on seven members of a four-generation Chinese family (Proc. Natl. Acad. Sci. U.S.A. 105, 2117, 2008). A phylogenetic picture of the resident microbes was assembled by sequencing rRNA genes. Parallel analysis of urine samples from the same family allowed the authors to correlate variations in resident microbes with variations in excreted metabolites. They found that Faecalibacterium prausnitzii was associated with the presence of dimethylamine, a tentative indicator of metabolic syndrome and diabetes. It may therefore eventually be possible to have bacterial indicators of disease states and of human well- being. A �safe� version of Ebola virus has been developed by researchers at the University of Wisconsin to help increase opportunities to study the deadly virus (Proc. Natl Acad. Sci. USA 105, 1129-1133, 2008). The gene coding for VP- 30 in the wild virus was replaced with a marker gene, thus disabling its capacity to multiply in normal human cells. If approved by regulatory authorities, this non-infectious virus could be studied in a broader variety of laboratories and enable speedier development of vaccines and antiviral compounds. Currently, work on Ebola viruses is conducted only in a small number of laboratories rated at biosafety level-4 (BSL-4). For more than 500 years, Christopher Columbus has been alternately blamed and exonerated for bringing syphilis to Europe. Now, a genetic analysis of Treponema strains indicates that syphilis is a close cousin to yaws, which is endemic in South America, suggesting that the malady has its roots in the Americas (PLoS Negl. Trop. Dis. 2, e148, 2008). Twenty-two Treponema samples isolated from human infections, including two collected from a Guyanese village with an active outbreak of yaws (T. pertenue), were studied. Four of 17 base pairs were identical between T. pallidum and T. pertenue. The overlap with any other kind of Treponema was limited to one or none of the sites. We usually live in harmony with tens of millions of bacteria in our gut. It is a commonly held perception that an imbalance in the normal commensal microbiota contributes to the development of inß ammatory bowel diseases. A study (Nature 453, 620�625, 2008) provides some basis for this perception. Using speciÞ c pathogen-free mice, it was found that a factor produced by Bacteroides fragilis, a common commensal bacterium in mammals, could actually prevent colitis caused by Helicobacter hepaticus. Use of prophylactic antibiotics for infective endocarditis before tooth extraction is becoming increasingly controversial. Using 16S ribosomal RNA sequencing and quantitative polymerase chain reaction assays, a study (Circulation 117, 3118, 2008) proÞ led the bacteria in sequential blood samples drawn from patients who had undergone tooth extraction with or without antibiotic treatment and from untreated patients who simply brushed their teeth. It was found that brushing alone caused a substantial increase in bacteria in blood samples. The risk of bacteremia following brushing was comparable to that *Corresponding author: (email: ) Department of Microbiology, Bhopal Memorial Hospital and Research Centre, Bhopal-462 038, MP, India www.ijmm.org 410 Indian Journal of Medical Microbiology vol. 26, No. 4 following a tooth extraction. This underscored the need for controlled clinical trials to evaluate current practices. It is a common assumption that most recurrent urinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) are caused by the persistence of UPEC strains in the faecal ß ora, which re-infect the bladder. Recent work on mice, however, suggests an additional explanation for UPEC persistence and recurrent UTIs (PLoS Med. 4, e329, 2007). In this model, UPEC strains invade the epithelial cells that line the bladder and form intracellular bacterial communities (IBCs). Some infected epithelial cells are expelled into the urine, whereas others release bacteria, many of which adopt a Þ lamentous morphology. These Þ lamentous bacteria can resist the host immune response, and ultimately the pathogen establishes an intracellular reservoir that is protected from both antibiotics and host immune surveillance. This Þ nding will have important implications for treatment of recurrent UTIs. Finally, there is some good news for travellers. Enterotoxigenic Escherichia coli (ETEC) are a major cause of travellers` diarrhoea. In a phase II trial, a candidate vaccine containing heat-labile enterotoxin, derived from ETEC, delivered by a skin patch, was tested among travellers to Mexico and Guatemala (Lancet 371(9629):2019-25, 2008). Participants were vaccinated before travel, with two patches given 2 to 3 weeks apart. They were found to be protected against moderate-to-severe diarrhoea. Source of Support: Nil, Conß ict of Interest: None declared. Indian Journal of Medical Microbiology Change of Editorial offi ce Beginning November 2008, IJMM ofÞ ce would be shifting base to the following address: Dr. Reba Kanungo Editor- in-Chief Indian Journal of Medical Microbiology Pondicherry Institute of Medical Sciences Kalapet, Puducherry- 605 014 Ph: 0413-2656271/72 Ext: 340, 178, 179 Mobile : 09443375275 Fax : 0413-2656273 Email: reba.kanungo@gmail.com Website: http://www.ijmm.org Website for manuscript submission to ijmm: http://www.journalonweb.com/ijmm Announcement MedknowPC Rectangle work_c3a3njp4nzajbmq22uxcxbzt6e ---- wp-p1m-38.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-38.ebi.ac.uk no 218202798 Params is empty 218202798 exception Params is empty 2021/04/06-02:09:29 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. 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Accordingly, all articles published in Science-including editorials, news and comment, and book reviews-are signed and reflect the individual views of the authors and not official points of view adopted by the AAAS or the institutions with which the authors are affiliated. Publisher: Richard S. Nicholson Editor: Daniel E. Koshland, Jr. Deputy Editor: Ellis Rubinstein Managing Editor: Monica M. Bradford International Editor: Alun Anderson Deputy Editors: Philip H. Abelson (Engineering and Applied Sciences); John I. Brauman (Physical Sciences); Thomas R. Cech (Biological Sciences) EDITORIAL STAFF Assistant Managing Editor: Dawn Bennett Senior Editors: Eleanore Butz, Martha Coleman, Barbara Jasny, Katrina L. Kelner, Phillip D. Szuromi, David F. Voss Associate Editors: R. Brooks Hanson, Pamela J. Hines, Kelly LaMarco, Unda J. Miller, L. Bryan Ray Letters: Christine Gilbert, Editor; Steven S. 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Canada: Fred Dieffenbach, Rt. 30, Dorset, VT 05251; 802-867-5581, FAX 802-8674464 * Mid- Atlantic: Richard Teeling, 28 Kimberiy Place, Wayne, NJ 07470; 201-904-9774, FAX 201-904-9701 * Southeast: Mark Anderson, 1915 Brickell Ave, Suite CC-1, Miami, FL 33129; 305-856-8567, FAX 305-856-1056 * Midwest: Don Holbrook, 1110 North Harvey, Oak Park, IL 60302; 708-386-6921, 708- 386-6950 * West Coast/W. Canada: Neil Boylan, 828 Cowper, Ste. A, Palo Alto, CA 94301; 415-323-3302, FAX 415-323- 3312 * Europe/Scandinavia: Nick Jones, UK; 44-647-52918, FAX 44-647-52053 Information for contributors appears on pages 35-37 of the 4 January 1991 issue. Editorial correspondence, including re- quests for permission to reprint and reprint orders, should be sent to 1333 H Street, NW, Washington, DC 20005. Telephone: 202-326-6500. London office: 071-494-0062. Subscription/Member Benefits Questions: 202-326-6417. Science: 202-326-6500. Other AAAS Programs: 202-326-6400. 6 DECEMBER 1991 VOLUME 254 NUMBER 5037 Pork Barrel "Science" T he polite term on Capitol Hill is "earmarking." But whether one calls it earmarking or pork barrel, it is a reprehensible activity practiced by a few powerful members of Congress. Moreover, it has reached a point where the negative impact on scientific projects is very real, as is apparent from the following excerpt of recent remarks by George Brown, chairman of the House Science, Space, and Technology Committee. "Mr. Speaker...I want...to comment on the.. .practice of adding unauthorized, unrequested earmarks for personal interest items. "This, of course, is in many ways a time-honored tradition of this body and could be overlooked if it were not for the severe budgetary environment that we have had to operate within this year and for the foreseeable future. This year, the budget reductions that Congress has had to make have made it entirely inappropriate to indulge in the earmarking that we are being asked to approve. ".. .I want to take a few moments to cite a few examples and explain why I believe this practice has simply gone too far. "In the NASA area, I am certain that my colleagues recall the debate earlier this year over the space station. That debate was, in many ways, a historic one. We were asked to make a major decision on whether we could afford to continue the space station when so many other programs were in dire need offunding. These included space science programs, housing programs, environmental programs, and veterans programs. We voted to continue the station, and there can be no doubt that many ofthese other meritorious programs have not received the funding they needed. "Yet the conference report [that is, final bill] contains over $100 million in projects that were never requested by the administration, never authorized, and never discussed on the floor. We were never given the choice between the station and these projects. These appear in the NASA portion of the budget, but some can scarcely even be called space projects. "The conferees generously set aside over $40 million for a vast variety of brick and mortar projects in West Virginia. These include $22.5 million in funding for a National Technology Transfer Center in Morgantown, WV. The proponent envisions that persons inquiring about technological advances that are taking place through government projects must write to West Virginia for the answer. It includes $7.5 million in continued funding for the Wheeling, West Virginia, Jesuit College. I do not believe anyone in Congress or in NASA knows what this will be used for. "It includes continued funding for a consortium of universities and consultants in the Saginaw, MI, area which somehow has emerged as the center for environmental research over the past 3 years.... NASA itself has little idea where this funding is going. "It includes $20 million for the Christopher Columbus Center for Marine Research in Baltimore. I stress Marine research, not Space research.... "The conference report terminates a vast variety ofNASA scientific projects such as the space infrared telescope,...the orbiting solar observatory.., and the flight telerobotic servicer. These are all projects that scientists have spent decades planning and developing. These are all projects that could have been funded with a little more restraint on the part of the conferees.... "I note that while the recommended funding level [for the National Science Foundation] represents an increase, the funding for research at NSF in this agreement is below that passed by either the House or the Senate. This is the only NSF function which is below the funding level approved by one of the Houses and is probably the most critical function at NSF.... "I must note with some concern that the conference agreement contains language earmarking $2 million for planning a demonstration for shared supercomputer use. While I agree with the need for this type of a program, I worry that we are moving dangerously close to earmarking within the NSF funding, a threshold which we have not crossed to date...." With regard to the pork barrel sites mentioned by Representative Brown, it is no coincidence that chairs of three of the relevant appropriation committees come from West Virginia, Maryland, and Michigan. While it is reassuring to have someone with George Brown's good sense in a key position in the House, his ability to influence is limited to his powers ofpersuasion, because he chairs an authorizing, not an appropriating, committee. Brown's willingness to take on this issue deserves the support ofthe entire scientific community.-RIcHARD S. NICHOLSON 6 DECEMBER 1991 EDITORIAL 1433 o n A p ril 5 , 2 0 2 1 h ttp ://scie n ce .scie n ce m a g .o rg / D o w n lo a d e d fro m http://science.sciencemag.org/ Pork Barrel "Science" RICHARD S. NICHOLSON DOI: 10.1126/science.254.5037.1433 (5037), 1433.254Science ARTICLE TOOLS http://science.sciencemag.org/content/254/5037/1433.citation PERMISSIONS http://www.sciencemag.org/help/reprints-and-permissions Terms of ServiceUse of this article is subject to the is a registered trademark of AAAS.ScienceScience, 1200 New York Avenue NW, Washington, DC 20005. The title (print ISSN 0036-8075; online ISSN 1095-9203) is published by the American Association for the Advancement ofScience 1991 by the American Association for the Advancement of Science o n A p ril 5 , 2 0 2 1 h ttp ://scie n ce .scie n ce m a g .o rg / D o w n lo a d e d fro m http://science.sciencemag.org/content/254/5037/1433.citation http://www.sciencemag.org/help/reprints-and-permissions http://www.sciencemag.org/about/terms-service http://science.sciencemag.org/ work_c5r2qjf5bferjhmae25xodrvdu ---- Correspondence Supercollider critics: learn from history Hugely expensive new accelerators are being proposed to look for unknown entities such as particles of dark matter and companions of the Higgs boson (see Nature 565, 398; 2019). Opponents of these plans could learn from history. Critics argue, for example, that such ‘big science’ projects drain money away from other research, a view that led to the cancellation of the US Superconducting Super Collider in 1993. To my knowledge, that cancellation brought no funding benefit to other sciences. And because Europe has already committed to the ITER fusion project for energy production in France, and to the LISA gravitational-wave experiment in space; successors to the Large Hadron Collider would not be competing for funding with those projects. Others are sceptical about the existence of new particles, given that nothing has materialized since the discovery of the Higgs boson in 2012. That puts me in mind of Spain’s reaction to Christopher Columbus, when he requested funding to explore a westerly route to Asia in the fifteenth century. His proposal was initially rejected by a royal commission, which pronounced that “so many centuries after the Creation, it is unlikely that anyone could find hitherto unknown lands of any value”. Columbus Three women with a claim to astatine In this International Year of the Periodic Table, we suggest that three unsung women — Yvette Cauchois, Berta Karlik and Traude Bernert — should also be celebrated (see B. Van Tiggelen and A. Lykknes Nature 565, 559–561; 2019). They all contributed to the discovery of the halogen astatine (At), one of the rarest elements in Earth’s crust. Astatine (atomic number 85) is radioactive. Cauchois and Horia Hulubei first detected the isotope astatine-218 in a sample of radon-222 in 1939 in Paris (M. Thoennessen Int. J. Mod. Phys. E 25, 1630004; 2016). Karlik and Bernert subsequently reported 218At (in 1942), then 216At and 215At (in 1943), in natural samples at the Institute for Radium Research in Vienna (B. Karlik Monatsh. Chemie 77, 348–351; 1947). And Dale Corson, Kenneth MacKenzie and Emilio Segrè synthesized and chemically characterized 211At, which doesn’t occur naturally, in 1940 in Berkeley, California. Misperceptions about allegiances during the Second World War could have influenced those adjudicating discovery assignments (see B. F. Thornton and S. C. Burdette Bull. Hist. Chem. 35, 86–96; 2010), and Cauchois and Hulubei’s experiments were largely forgotten. With the acceptance of synthetic elements into the periodic table, element 85 was credited to the Berkeley group. Brett Thornton Stockholm University, Stockholm, Sweden. Shawn Burdette Worcester Polytechnic Institute, Worcester, Massachusetts, USA. brett.thornton@geo.su.se Don’t single out Chinese names I agree with Cristina Muñoz- Pinedo that researchers and scholars should have unique identifiers such as those provided by ORCID, but I object to the singling out of Chinese scientists for not complying with the system (Nature 565, 161; 2019). When different cultures seek to do business, all parties need to make compromises. Although “millions of Chinese people share the same 100 last names”, millions do not — there are more than 5,000 surnames in China. The 100 most common Chinese surnames are used by roughly 80% of the country’s population (see go.nature. com/2sjqufi; in Chinese), a situation that would hold for any country with a large enough population. There are probably many scholars with the last names García or Hernández, say, in Muñoz-Pinedo’s Spain and in the Spanish-speaking nations of Central and South America. In my view, Nature and other journals should follow an initiative by the Journal of Biological Chemistry and the Journal of Neuroscience (see go.nature.com/2xhiIj5), among others, to list authors in the script of their own language — whether Arabic, Urdu, Kanji or other — as well as in the Roman alphabet and in ORCID or similar. If you can accommodate accented letters in European names, you should extend comparable courtesy to other international scholars. Zhongmin Wang Memorial Sloan Kettering Cancer Center, New York City, USA. wangz2@sloankettering.edu Forests are still key to climate action We disagree with those who caution against relying on forests as a solution to global warming until the warming effects of trees themselves are better understood (see Nature 565, 280–282; 2019). Science looks worse as it gets better It is easy to assume that science is more flawed than in the past, given widespread coverage of the reproducibility crisis, perverse incentives and P-value hacking, alongside a proliferation of corrective measures (see, for example, C. K. Gunsalus et al. Nature 566, 173–175; 2019). But it could be that we are now seeing more problems simply because we are more alert to them. Consider related lessons from medicine. When a new treatment method is invented for a particular disease, there is typically an increase in the number of people who might benefit from that treatment, because conditions that were previously undetectable or Forests are currently the safest, most cost-effective way to avoid dangerous increases in global warming, through their retention, management and restoration (B. W. Griscom et al. Proc. Natl Acad. Sci. USA 114, 11645–11650; 2017). The land sink for carbon (which is made up mainly of intact forests) captures at least 30% of global emissions generated by human activity (C. Le Quéré et al. Earth Syst. Sci. Data 10, 405–448; 2018). And there is almost universal agreement that increased carbon dioxide in the atmosphere will boost the rates of carbon uptake on land (G. Schurgers et al. Geophys. Res. Lett. 45, 4329–4336; 2018). Simple tree-planting programmes might not simulate the climate-mitigation capabilities attributed to established forests. Until the warming effects of some trees are quantified and explained, forests must be managed to optimize their capacity to act as sinks. James E. M. Watson* University of Queensland, St Lucia, Australia. jwatson@wcs.org *On behalf of 4 correspondents (see go.nature.com/2tccpdy for full list). ignored are now uncovered systematically. Science could be the same. Today, we study in minute detail the dynamics of discovery, careers, teams and institutions, sometimes exposing issues that we didn’t know existed (see S. Fortunato et al. Science 359, eaao0185; 2018). That, to me, is grounds for optimism: such intense scrutiny should markedly improve the quality of science. Dashun Wang Northwestern University, Evanston, Illinois, USA. dashun.wang@northwestern.edu sailed west anyway and found “hitherto unknown” lands that have dominated the planet for the past century. John Ellis King’s College London, UK. john.ellis@cern.ch 2 1 M A R C H 2 0 1 9 | V O L 5 6 7 | N A T U R E | 3 1 1 © 2019 Springer Nature Limited. All rights reserved. work_caauczeg4vbn3iwhwr3gvbshn4 ---- [PDF] On viral epidemics, zoonoses and memory | Semantic Scholar Skip to search formSkip to main content> Semantic Scholar's Logo Search Sign InCreate Free Account You are currently offline. Some features of the site may not work correctly. DOI:10.1016/S0966-842X(99)01586-3 Corpus ID: 38613426On viral epidemics, zoonoses and memory @article{WainHobson1999OnVE, title={On viral epidemics, zoonoses and memory}, author={S. Wain‐Hobson and A. Meyerhans}, journal={Trends in Microbiology}, year={1999}, volume={7}, pages={389 - 391} } S. Wain‐Hobson, A. Meyerhans Published 1999 Biology, Medicine Trends in Microbiology Given this, what might have happened when Christopher Columbus et al. and attendant microorganisms travelled into virgin territory? As American Indians had been geographically isolated from the conquistadors for tens of thousands of years, much of the local human and animal microbial fauna, particularly the rapidly mutating RNA viruses, would have been antigenically very distinct from those aboard the Santa Maria. Eurasians had harnessed the horse, dog, pig, goat and cow to mention just a few… Expand View on Elsevier europepmc.org Save to Library Create Alert Cite Launch Research Feed Share This Paper 5 CitationsBackground Citations 1 View All Topics from this paper Smallpox Yellow Fever HIV Infections Name citation Microorganism Zoonoses Rivet Device Component Pathogenic organism 5 Citations Citation Type Citation Type All Types Cites Results Cites Methods Cites Background Has PDF Publication Type Author More Filters More Filters Filters Sort by Relevance Sort by Most Influenced Papers Sort by Citation Count Sort by Recency Das zoonotische Potenzial feliner und boviner F. Romen 2007 PDF Save Alert Research Feed The Human/Animal Interface: Emergence and Resurgence of Zoonotic Infectious Diseases M. Greger Biology, Medicine Critical reviews in microbiology 2007 199 PDF Save Alert Research Feed Extensive MHC class I-restricted CD8 T lymphocyte responses against various yeast genera in humans. T. Heintel, F. Breinig, M. Schmitt, A. Meyerhans Biology, Medicine FEMS immunology and medical microbiology 2003 29 PDF Save Alert Research Feed Enabling systems-level analyses of the host response to infectious diseases in bovine and other mammalian species Khosravizadeh Foroushani, Amir Bahram Biology 2014 PDF View 2 excerpts, cites background Save Alert Research Feed COMPARATIVE IMMUNOLOGY-BASED APPROACHES TO VETERINARY DISEASES D. Barreda, A. Rieger, N. Girard, Shannon D. G. Clarahan, Afolabi F. Eleyinmi Biology 2011 PDF Save Alert Research Feed References SHOWING 1-10 OF 30 REFERENCES SORT BYRelevance Most Influenced Papers Recency Cowpox: reservoir hosts and geographic range. J. Chantrey, H. Meyer, +6 authors M. Bennett Biology, Medicine Epidemiology and infection 1999 202 PDF Save Alert Research Feed Genetic and Experimental Evidence for Cross-Species Infection by Swine Hepatitis E Virus X. J. Meng, P. Halbur, +5 authors S. Emerson Biology, Medicine Journal of Virology 1998 546 PDF Save Alert Research Feed Isolation of a new human retrovirus from West African patients with AIDS. F. Clavel, D. Guétard, +7 authors C. Rouzioux Biology, Medicine Science 1986 1,203 Save Alert Research Feed Cross-reactivities in memory cytotoxic T lymphocyte recognition of heterologous viruses L. Selin, S. Nahill, R. Welsh Biology, Medicine The Journal of experimental medicine 1994 342 PDF Save Alert Research Feed A novel hantavirus associated with an outbreak of fatal respiratory disease in the southwestern United States: evolutionary relationships to known hantaviruses. B. Hjelle, S. Jenison, +5 authors G. Myers Biology, Medicine Journal of virology 1994 155 PDF Save Alert Research Feed Comparisons of Highly Virulent H5N1 Influenza A Viruses Isolated from Humans and Chickens from Hong Kong D. Suarez, M. Perdue, +4 authors D. Swayne Biology, Medicine Journal of Virology 1998 351 PDF Save Alert Research Feed Isolation of a Coronavirus from Kidney Biopsies of Endemic Balkan Nephropathy Patients Branislava Uzelac-Keserović, P. Spasić, +6 authors K. Apostolov Medicine Nephron 1999 30 Save Alert Research Feed Detection of a Novel Bovine Lymphotropic Herpesvirus J. Rovnak, S. Quackenbush, R. Reyes, J. Baines, C. Parrish, J. Casey Biology, Medicine Journal of Virology 1998 64 PDF Save Alert Research Feed Three closely related herpesviruses are associated with fibropapillomatosis in marine turtles. S. Quackenbush, T. Work, +8 authors J. Casey Biology, Medicine Virology 1998 157 PDF Save Alert Research Feed Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness. K. Subbarao, A. Klimov, +13 authors N. Cox Biology, Medicine Science 1998 1,329 PDF Save Alert Research Feed ... 1 2 3 ... Related Papers Abstract Topics 5 Citations 30 References Related Papers Stay Connected With Semantic Scholar Sign Up About Semantic Scholar Semantic Scholar is a free, AI-powered research tool for scientific literature, based at the Allen Institute for AI. 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Message ID: 218200543 (wp-p1m-39.ebi.ac.uk) Time: 2021/04/06 02:09:26 If you need further help, please send an email to PMC. Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_ccnwtncrffalnmrljycy6sfdq4 ---- Surname and Y chromosome in Southern Europe: a case study with Colom/Colombo ARTICLE Surname and Y chromosome in Southern Europe: a case study with Colom/Colombo Luis Javier Martı́nez-González1, Esther Martı́nez-Espı́n2, Juan Carlos Álvarez3, Francesc Albardaner4, Olga Rickards5, Cristina Martı́nez-Labarga5, Francesc Calafell*,6 and José Antonio Lorente1,3 According to most historians, Christopher Columbus was born in Genoa, Italy. However, based on some key facts in the discoverer’s biography, as well as in the linguistic analysis of his texts, some historians and linguists believe that Columbus could have been of Catalan origin. A Ligurian Columbus would have carried the Colombo surname, whereas he would have been called Colom if he were Catalan. In order to test whether it would be possible to discriminate between a Ligurian or a Catalan origin were Columbus’ Y-chromosome haplotype to be retrieved, we genotyped 17 Y-chromosome STRs in 238 Spanish (from Catalonia, Valencia, and the Balearic Islands) and French Colom men, and 114 North Italian Colombo (from Liguria, Lombardy, and Piedmont). The Italian samples and, in particular, the Lombard Colombos were genetically as diverse as the general population, and we found little evidence of clusters of haplotypes that could indicate descent from a single founder. Colombo is actually the most frequent surname in Lombardy, where foundlings and orphans used to be given the surname Colombo. By contrast, Y-chromosome diversity was reduced in the Iberian Colom, where most of the men had Y chromosomes belonging to a few lineages. This implies that a positive identification would be more likely if Columbus were of Catalan descent. In this study, we have shown the diverse dynamics of two surnames linked by their etymology, in what is, to the best of our knowledge, the first genetic analysis of a surname in Southern Europe. European Journal of Human Genetics (2012) 20, 211–216; doi:10.1038/ejhg.2011.162; published online 17 August 2011 Keywords: surnames; Y chromosome; Christopher Columbus INTRODUCTION The origin of Chistopher Columbus is the object of an ongoing debate among historians. The most widely accepted hypothesis is that Christoper Columbus was Cristoforo Colombo, from Genoa, and over 200 texts document the life of a Cristoforo Colombo; the discoverer referred to himself as a Genoese in his deed of primogeni- ture of 1498, although many scholars contest the authenticity of this document. However, several lines of evidence, mostly linguistic, question that Columbus could be Genoese and point instead to a Catalan origin; he would be Cristòfol Colom rather than Cristoforo Colombo. Throughout Columbus’s life, he was never referred as Colombo; before 1492, his contemporaries called him Colomo and Colom, and, after the first voyage, he was almost exclusively referred to with the Spanish form Cristóbal Colón. He wrote in Spanish with lexical mistakes and phonetical misspellings that are typical of a Catalan native speaker.1,2 According to Merrill,2 the Genoese Cristoforo Colombo was a modest wool carder and cheese merchant with no maritime training, whose age does not match that of Columbus, and it is unlikely that a tradesman would marry a Portuguese noblewoman, as Columbus did. A genetic analysis could settle this dispute. Columbus’ Y-chromo- some haplotype could be compared with that of extant North Italian Colombo and Catalan Colom men; a match, with the pertinent statistical assessment, could indicate which is the most likely origin of the discoverer. Both the Italian Colombo and the Catalan Colom derive from the Latin colmbus, ‘dove’. In Italy, 21 068 telephone landlines are registered to individuals named Colombo (online search on November 2010, http://www.paginebianche.it). Most of those (16 169, 76.7%) were found in the Lombard provinces of Lecco, Monza and Brianza, Varese, Milan, and Como, which make up 9.6% of the total Italian popula- tion. In fact, Colombo is the most frequent surname among telephone customers in Lombardy. Significant numbers of Colombo were found in the Piedmontese provinces that border Lombardy, and 486 telephone directory entries for Colombo were found in Liguria (2.3%), the region around Genoa; Colombo ranks in 27th position among Ligurian telephone customers. The abundance of people named Colombo in Milan and the surrounding region can be explained by the fact (according to Mario Colombo – Gruppo Ricerche Storiche Borsano, cited by http://www.cognomiitaliani.org/ cognomi/cognomi0003col.htm) that, until 1825, the orphans and foundlings hosted by the orphanage at the Ospedale Maggiore in Milan were given the surname Colombo, because a dove figured prominently in the crest of the Ospedale Maggiore. In Spain, 4056 males and females carry Colom as a paternal surname, according to official registry figures reported by the Spanish National Statistical Institute (http://www.ine.es/fapel/FAPEL.INICIO). Of those, 1207 (29.8%) were born in the Balearic Islands, 1976 (48.7%) in Catalonia, and 564 (13.9%) in the Valencia region. Catalan is spoken in these three regions; the Balearics and Valencia were Received 2 February 2011; revised 7 June 2011; accepted 7 July 2011; published online 17 August 2011 1GENYO – Centro Pfizer-Universidad de Granada-Junta de Andalucı́a de Genómica y Oncologı́a, Granada, Spain; 2LORGEN GP, S.L., Granada, Spain; 3Department of Legal Medicine, University of Granada, Granada, Spain; 4Centre d’Estudis Colombins, Òmnium Cultural, Barcelona, Spain; 5Centre of Molecular Antropology for Ancient DNA Studies, Department of Biology, University of Rome Tor Vergata, Rome, Italy; 6Institute of Evolutionary Biology (CSIC-UPF), CEXS-UPF-PRBB, Barcelona, Spain *Correspondence: Dr F Calafell, Institute of Evolutionary Biology (CSIC-UPF), CEXS-UPF-PRBB, Doctor Aiguader 88, 08005 Barcelona, Catalonia, Spain. Tel: +34 93 316 08 42; Fax: +34 93 316 09 01; E-mail: francesc.calafell@upf.edu European Journal of Human Genetics (2012) 20, 211–216 & 2012 Macmillan Publishers Limited All rights reserved 1018-4813/12 www.nature.com/ejhg http://dx.doi.org/10.1038/ejhg.2011.162 http://www.paginebianche.it http://www.cognomiitaliani.org/cognomi/cognomi0003col.htm http://www.cognomiitaliani.org/cognomi/cognomi0003col.htm http://www.ine.es/fapel/FAPEL.INICIO mailto:francesc.calafell@upf.edu http://www.nature.com/ejhg conquered by the Crown of Aragon (constituted by Catalonia and Aragon proper) from the local Muslim rulers in the 13th century and repopulated mostly with Catalans. In 1659, the Treaty of the Pyrenees awarded the fraction of Catalonia lying north of the Pyrenees (known as the Roussillon) to France; 91 landlines are registered to Coloms in the Roussillon. The analysis of Y-chromosome haplotypes in samples of men carrying the same surname can provide invaluable information about the genealogy linking these men, up to the point that Y chromosome analyses are being routinely used by the general public to retrace family histories.3 In England, it has been shown that it is possible to define clusters of phylogenetically related Y-chromosome haplotypes that are likely to represent the descendants of a single founder, and, from the diversity they accumulate, a time depth can be estimated that is compatible with the historical time in which paternal surname inheritance is systematized.4 In general, in England, the more frequent surnames have more diverse Y-chromosome haplotypes, as if surname frequency was driven by polyphyletism (ie, the repeated assumption of a surname by different, unrelated people).4 On the contrary, no such effect was found in Ireland,5 and the success of a surname was driven by social factors rather than by polyphyletism. It should be noted that, to the best of our knowledge, European analyses of Y-chromosome diversity in specific surnames are restricted to the British Isles (see also ref. 6). The goal of the present research is to study the feasibility of identifying the geographical origin of Christopher Columbus in the event that his Y chromosome could be retrieved and compared with the extant Colom and Colombo men. To that effect, we have genotyped 17 Y-chromosome STRs in samples of Colombo collected in Northern Italy (Lombardy, Liguria, and Piedmont), and of Colom collected in Catalonia, the Balearic Islands, Valencia and the Roussillon. To the best of our knowledge, this is the first study of the genetics of a surname in continental Europe. METHODS Samples Men with the surname ‘Colom’ were sampled in Catalonia (n¼126, including one sample from Andorra), the Balearic Islands (n¼50), Valencia (n¼45), and the Pyrénées Orientales département of Southeast France (n¼17). Lists of men bearing the Colom surname were obtained from public telephone directories. Participants were shown the lists and asked to identify any relatives, in order to avoid sampling closely related men. A total of 18 men bearing the Colomb, Colom, Coulom, Coulomb, Coulon, Collon, Colon, Collomb, and Coullon surnames were sampled in Southwest France, in Bordeaux, and the rest of the Gironde département. The Colombo surname was sampled in three Italian regions: Lombardy (n¼52), Liguria (n¼48), and Piedmont (n¼14) (Figure 1). Additionally, reference samples of 59 random Catalan males (with all eight great-grandparents born in Catalonia) and 50 North Italian men (with three generations of paternal line ancestry in Liguria and Lombardy) were gathered. In all cases, biological samples were obtained as buccal swabs, except for control Northern Italians, in which blood samples were collected at the Blood Transfusion Centre of the ‘Umberto I’ Hospital in Rome. Written informed consent was obtained from all participants. DNA extraction and genotyping DNA was extracted from buccal swabs using a standard organic method (proteinase K and DTT digestion, followed by phenol–chloroform extraction and Microcon 100 purification and concentration). Amplification of samples was performed with about 1 ng of target DNA. For blood samples, DNA was extracted following the salting-out procedure of Miller et al7. A total of 17 Y-chromosome STR loci (DYS19, DYS385a,b, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, and GATAH4) contained in the AmpFlSTRYFiler PCR Amplification kit (Applied Biosystems, Foster City, CA, USA)8 were genotyped according to the manufacturer’s instructions. Alleles were separated and detected using an Applied Biosystems ABI 310 genetic analyzer. Fragment sizes were analyzed using the GeneScan Analysis and Genotyper ver. 2.0 Software (Applied Biosystems). The sample run data were analyzed together with an allelic ladder and positive and negative controls. The alleles were named according to the number of repeated units based on the sequenced allelic ladder (ISFG recommendations).9 Data analysis Basic descriptive statistics were estimated with Arlequin 3.1 (http://cmpg.unibe. ch/software/arlequin3/).10 Each individual was allocated to a haplogroup using a Bayesian approach11 as implemented in Haplogroup Predictor (http:// www.hprg.com/hapest5/), with the ‘Area Selection’ field set to ‘Equal priors’; haplotypes with a posterior probability o95% were left unclassified. J2a1 and its subgroups (J2a1b, and J2a1h) were pooled, as Haplogroup Predictor often failed to discriminate among them with the current 17-STR haplotypes. We validated Haplogroup Predictor by running it through a previously published sample of 307 Y chromosomes from Catalonia, Valencia, and the Balearic Islands.12 SNPs and a widely overlapping set of Y-chromosome STRs had been typed in those samples; 14-STR-haplotypes were input in Haplogroup Pre- dictor, with 11 (DYS19, DYS385, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, and DYS439) matching those in the present study, plus DYS460, DYS461, and DYS462. Within each haplogroup, median joining networks13 were drawn with Network 4.5.1.6 (http://www.fluxus-engineering.com), by giving each STR a weight inversely proportional to its variance, and equating the average variance to a weight of 10. FST distances based on the number of different alleles among Y-chromosome haplotypes were computed for pairs of populations with Arlequin 3.5 (http://cmpg.unibe.ch/software/arlequin35/),14 and, after adding a small value to the entire matrix in order to remove negative values while preserving ordinality, it was plotted with multidimensional scaling as imple- mented in Statistica 7.0 (Statsoft, Inc., Tulsa, OK, USA). The time depth of inherited surnames is expected to be 500–600 years in Spain and Italy;3 two extant bearers of the same surname would have at most double that time to accumulate mutations at their Y-chromosome STRs. The overall genealogical mutation rate for the 17 STRs we genotyped is 4.167�10�2 per generation (as compiled from multiple studies by Sascha Willuweit and Lutz Roewer and reported in http://www.yhrd.org, 22 October 2010), or, with a generation time of 25 years, 1.667�10�3 per year, or one mutation per 600 years. Thus, at most, bearers of the same surname are expected to differ by two Figure 1 Populations and localities where Colom/Colombo men were sampled. Dot area is proportional to the number of individuals sampled in that locality. The Y chromosome in Colom/Colombo men LJ Martı́nez-González et al 212 European Journal of Human Genetics http://www.hprg.com/hapest5/ http://www.hprg.com/hapest5/ http://www.fluxus-engineering.com http://www.yhrd.org mutations in their Y-chromosome STRs. Pairwise comparison of all reference haplotypes in Catalans and Italians showed that 19 out of 5886 pairs (0.32%) showed r2 differences, in contrast with 2.99% of the Colom/Colombo chromosome pairs. Therefore, we used these observations to construct an ad hoc heuristic to identify groups of Colom/Colombo men with shared recent ancestry. Within each haplogroup median network, haplotypes that could be linked to another haplotype by an edge at most two mutations long were grouped and were considered as descendants of a common founder. However, this algorithm has the potential to create long strings of connected haplotypes that might be false positives. We postprocessed the lineages obtained in the first pass by eliminating those with times to the most recent common ancestor 41000 year and replacing those with the lineages (if any) that could be obtained with the more stringent definition of descent lineage adopted by King and Jobling.4 Overall, we also compared the lineages obtained with our method with those produced with King and Jobling’s. Time to the most common recent ancestor within lineages was computed with the r method15,16 with Network 4.5.16. RESULTS Haplotype, haplogroup and lineage assignment for each individual can be found in Supplementary Information. Basic descriptive statis- tics for the Colom/Colombo and reference samples are shown in Table 1. The Catalan and Northern Italian reference samples were quite diverse, and all haplotypes were different from each other (although one Catalan and one Northern Italian individual shared the same haplotype). Italian Colombo samples showed a slight reduction in haplotype diversity, which was more pronounced in the Iberian Colom, particularly in those from Valencia and Majorca. Pairwise differences in repeat size were reduced only in Majorcan Coloms, probably because in the remaining Colom/Colombo samples, different haplogroups were still well represented. The homogeneity of Majorcan Colom haplotypes cannot be attributed to the insular nature of the general population: the Majorcan samples in Adams et al12 showed, for a widely overlapping set of SNPs, no reduction of haplotype diversity with respect to the mainland (0.9921 vs 0.9984 in Catalans; Majorcan Coloms had H¼0.5665 for the overlapping STRs). General similarities between the samples were measured with FST and represented by means of multidimensional scaling (Figure 2a). Stress was 1.42%, below the 1st percentile for random data sets.17 The Balearic Colom appeared as extreme outliers, to the point that they might obscure the relations among other samples. When the Balearic Colom were removed from this analysis (Figure 2b), the Lombard and Ligurian Colombo, and the SW French Colomb appeared closer to the general Northern Italian and Catalan populations than other samples were. Haplogroups were inferred for each individual based on their STR haplotypes. A previous validation study (see Methods) showed that 302 out of 307 (98.4%) Catalan, Valencian, and Balearic Y-chromo- some STR haplotypes could be allocated to a haplogroup, and only three haplogroup assignments (1%) were erroneous: R1b3*, J2, and K(xP) chromosomes were called as R1a, J1, and R1b, respectively. Haplogroup frequencies are shown in Table 1. Overall, 4 out of 479 chromosomes (0.84%) could not be classified. Most Colom/Colombo samples were similar in haplogroup frequencies to their respective reference populations. Estimated haplogroup frequencies were similar Table 1 Descriptive statistics of the genetic diversity in the different samples and percent frequencies of estimated haplogroups Sample N k D (SD) p (SD) E1b1b G2a I1 I2a I2b J1 J2a1 J2b L R1a R1b T unc. Catalan ‘Colom’ 126 57 0.9685 (0.0067) 14.899 (8.066) 4 5.6 1.6 0 0.8 0 11.1 4 0 5.6 65.1 0 2.4 Balearic ‘Colom’ 50 19 0.7469 (0.0663) 7.061 (9.454) 4 6 0 0 2 0 0 0 0 0 88 0 0 Valencian ‘Colom’ 45 20 0.9424 (0.0156) 16.683 (10.239) 0 0 0 0 0 31.1 0 11.1 0 0 57.8 0 0 SE French ‘Colom’ 17 14 0.9559 (0.0436) 15.971 (8.829) 11.8 5.9 11.8 0 0 5.9 0 5.9 0 0 58.8 0 0 SW French ‘Colomb’ 18 16 0.9869 (0.0229) 11.608 (5.936) 5.6 11.1 0 0 0 0 0 0 0 0 83.3 0 0 Lombard ‘Colombo’ 52 50 0.9985 (0.0042) 16.955 (7.638) 7.7 5.8 3.8 0 5.8 3.8 7.7 0 0 1.9 59.6 3.8 0 Piedmontese ‘Colombo’ 14 13 0.9890 (0.0314) 17.604 (6.231) 14.3 14.3 0 7.1 14.3 0 14.3 0 0 0 35.7 0 0 Ligurian ‘Colombo’ 48 36 0.9876 (0.0068) 17.716 (7.104) 8.3 6.3 2.1 6.3 2.1 0 8.3 6.3 2.1 0 56.3 0 2.1 Catalan reference 59 59 1 (0.0031) 14.788 (7.181) 1.7 5.1 5.1 3.4 3.4 1.7 5.1 0 0 0 72.9 1.7 0 N Italian reference 50 50 1 (0.0040) 16.940 (7.710) 8 4 6 2 2 4 10 2 0 0 60 2 0 Abbreviations: D, haplotype diversity; k, number of different haplotypes; N, sample size; p, average number of pairwise differences in absolute number of repeats; Unc, unclassified haploypes. Figure 2 (a) Multidimensional scaling plot based on FST distances among haplotypes. Stress was 1.4%. (b) MDS after removing the outlying Balearic Colom sample. Stress was 7.7%. Abbreviations: B, Balearic; C, Catalan; V, Valencian; FSE, SE French; FSW, SW French; LO, Lombard; LI, Ligurian; PI, Piedmontese; CTR, Catalan control sample; ITR, Northern Italian control sample. The Y chromosome in Colom/Colombo men LJ Martı́nez-González et al 213 European Journal of Human Genetics across samples, and the most salient specific features were the high frequency of J1 in the Coloms from València (31.1%, compared with 0–4% in the other samples) and the low frequency of R1b in the small Piedmontese Colombo sample (35.7% as opposed to 56–88% elsewhere). Median Joining networks for Colom/Colombo chromosomes in the major haplogroups are shown in Figures 3 and 4. These were used to detect possible founder lineages (groups of chromosomes that may descend from a single founder of the surname) as decribed in the Methods section. When we applied this approach to the reference Catalan and Northern Italian samples (which were collected regardless of surname), the 109 chromosomes represented 95 different lineages, with a maximum frequency of 5 chromosomes in Catalonia. In the total Colom/Colombo sample, 153 lineages were detected, most (91/135¼67.4%) being represented by a single chromosome. By contrast, the eight most frequent lineages (Table 2) comprised 40.5% of the total sample, but this fraction varied from 12.5% in the Ligurian to 82% in the Balearic. Estimated ages and places of origin are shown also in Table 2, as well as the corresponding core haplotypes (descent clusters as defined more narrowly by King and Jobling4). All major lineages are clearly geographically clustered in their distribution. Within each Colom/Colombo sample, the number and diversity of lineages varied greatly. Number of lineages and lineage diversity (computed as if it were haplogroup diversity) can be found in Table 3. Although in the Italian Colombo, the number and diversity of lineages is close to that of the general population, in the Iberian Colom (particularly in the Valencian and Balearic), a few lineages made up a sizeable portion of the chromosomes. In the Catalan Colom sample, the four most frequent lineages comprised 40.5% of the sample; two of those have clear geographical clusterings. Lineage 77 comprised 82% of all Balearic Coloms, which is rare elsewhere and is dominated by a single haplotype covering 58.5% Figure 3 Median joining networks for the Colom/Colombo chromosomes in each estimated haplogroup. Dotted ovals indicate lineages comprising more than one haplotype. The Y chromosome in Colom/Colombo men LJ Martı́nez-González et al 214 European Journal of Human Genetics of the Balearic Colom in this lineage. In Valencia, four distinct lineages cover 77.8% of the chromosomes. Of note is lineage 48, which was predicted to be in haplogroup J1, which is rare in the Iberian Peninsula (0–3%12) and with 12 chromosomes carrying the distinct DYS458*16.2 allele, which has a frequency in Europe of 10/9366 (1.068�10�3). The Italian samples were more diverse than the Iberian ones, without frequent lineages that could point to a few discrete origins for the surname. No lineage contained more than four chromosomes in Italy. DISCUSSION We have found that Colombo men in North Italy, particularly in Lombardy, carry in their Y chromosomes an array of haplotypes as diverse as that of the general population, whereas the Catalan-speaking Coloms show clear signs of founding effects, espe- cially in València and Majorca. In North Italy, haplotype and lineage diversity was extreme in Lombardy and less pronounced in Liguria. This observation matches the frequency of Colombo in each region: it is the most frequent surname in Lombardy, but only the 27th in Liguria. We could ask whether the high frequency by itself is sufficient to explain why a sample of Lombard Colombos is as diverse as the general population, or whether the orphanage at the Ospedale Maggiore in Milan had a role in increasing genetic diversity in the Colombos by giving that name to foundlings. Two considerations point indeed for a contribu- tion of the foundlings: ‘Colombo’, that is, ‘dove’, does not seem a type of surname that would have the most independent origins, unlike trade names (‘Smith’) or patronyms (‘Jones’). In Campania, a South Italian region, the most frequent surname is Esposito, which was given solely to foundlings. Genetic diversity in the Ligurian Colombos is high to the point that in a sample of 48 individuals, we found 36 different haplotypes and estimated 34 different founding events. Still, this slight reduction is sufficient to set the Ligurian Colombos apart both from the Northern Italian general population and from the Lombard Colombos, and, as seen in Figure 1, they are further apart from the Catalan Coloms; they appear closer to the Valencian Coloms, but, as discussed below, this is due just to the outlier position of the latter. Figure 4 Median joining network for the estimated R1b chromosomes. Lineages comprising more than one haplotype are indicated with colored lines. Population color codes as in Figure 3. Table 2 Major lineages found in the Colom/Colombo samples Lineage HG Frequency/Core lineage Median Haplotype YHRD core matches Age (SD)/Core lineage Geographical origin 77 R1b 60 (41 B, 8 C, 6 F, 4 V, 1 PI) 49 (38 B, 5 C, 3 F, 3 V) B-12 3/13 578 (153)/269 (88) Majorca 73 R1b 22 (16 C, 5 F, 1 PI) 21 (16 C, 5 F) C-004 2/3 136 (67)/86 (64) NE Catalonia 48 J1 14 (14 V) 13 (13 V) V-13 0/4 643 (361)/508 (323) S Valencia 51 J2a1 14 (14 C) 9 (9 C) C-003 0/2 557 (250)/200 (200) W Catalonia 70 R1b 13 (13 C) 13 (13 C) C-124 0/2 46 (46)/46 (46) NW Catalonia 85 R1b 13 (9 V, 4 C) 11 (8 V, 3 C) V-008 0/4 500 (245)/360 (355) N Valencia Abbreviations: B, Balearic; C, Catalan; HG, predicted haplogroup; V, Valencian. Core lineage: lineage as defined with the more stringent definition by King and Jobling.4 Frequency: total and regional absolute frequencies. YHRD core matches: haplotypes in the core lineage with matches in the YHRD database. Lineages with absolute frequency Z10 are shown. See Supplementary Information for the composition of each haplotype. Table 3 Descriptive statistics of the Y-chromosome lineages in the different samples Sample N kl Dl Catalan ‘Colom’ 126 35 0.9476 Balearic ‘Colom’ 50 7 0.3282 Valencian ‘Colom’ 45 10 0.8333 SE French ‘Colom’ 17 11 0.9045 SW French ‘Colomb’ 18 14 0.9672 Lombard ‘Colombo’ 52 45 0.9940 Piedmontese ‘Colombo’ 14 13 0.9890 Ligurian ‘Colombo’ 48 34 0.9832 Catalan reference 59 53 0.9931 N Italian reference 50 47 0.9976 Abbreviations: Dl, lineage diversity; kl, number of different lineages; N, sample size. The Y chromosome in Colom/Colombo men LJ Martı́nez-González et al 215 European Journal of Human Genetics The Catalan Coloms show clear founder effects that also correspond with geographical origins; four major clusters explained 40.5% of the individuals. Colom is much less frequent than Colombo: it ranks 467th among surnames in Catalonia, and is carried by 0.027% of the population. It falls below the limit (6000 bearers) under which King and Jobling4 suggest that it is feasible to predict a surname from a Y-chromosome haplotype using the same set of STR markers we employed. The situation is more extreme in Valencia and the Balearics, and is reflected also in their position in the multidimensional scaling plot. In Valencia, four lineages covered 77.8% of the sample, again with clear geographical clustering. Given the history of the resettle- ment of Valencia, one could expect that those lineages would also be represented in Catalonia, but we could not identify those origins. Then, the origins of Colom in Valencia could be local: the estimated TMRCAs (Table 2) hardly overlap with the resettlement age, 750 ya. Alternatively, the Catalan descendants of the founders were not in our sample, either because we could not find them (although our sample contains B12% of the Catalan Colom men before excluding known relatives), or because their paternal lines became extinct. A similar situation is found in the Balearics, where the Coloms are dominated by a single lineage that comprises 82% of the sample. As in the case of the Valencian Colom, and for similar reasons, a clear founder could not be identified in the mainland. We analyzed three other samples: the Southeast French Colom, which were linked to the Colom in Northeast Catalonia. Both regions have strong geographical, linguistic, and historic bonds. The Y chromosomes of the Southwest French Colomb reflected their mixed origins, given the variety of spellings and geographic origins gathered in that sample. Finally, the Alessandria Piedmontese Colombo seemed connected to the Ligurian Colombo, although, given its small sample size (n¼5), no clear conclusions can be derived. We have also shown that Colombo and Colom are two distinct surnames with no clear genealogical connection, and local origins in Italy and Spain. The dove, probably as a nickname, has originated surnames in many languages: Palomo (Spanish), Pigeon (French), Dove (English), Taube (German), and Golub (various Slavic languages) among others. The main reason for this research was trying to establish whether Christopher Columbus’ Y-chromosome haplotype, if retrieved, could be allocated to Liguria or to Catalonia. The most convincing evidence for either origin would be a match with a geographically specific descent cluster. If we set a simple, arbitrary threshold at a frequency of four chromosomes in each sample, then the cumulative frequencies of such lineages are 71, 87, and 82% of the Catalan, Valencian, and the Balearic Coloms, while they are only 18 and 0% in the Ligurian and Lombard Colombos, in which only lineage 109, found in four Ligurians, would provide the possibility for a specific match. On the contrary, and as also discussed above, the Colom lineages are much more geographically specific. Then, if we use as a criterion for identification a match with such lineages, a positive identification would be much more likely for a Catalan than for a Ligurian Columbus. A match with a singleton Catalan or Ligurian haplotype should be treated with great caution, and, while indicative, would be by no means conclusive. Assessing the relative likelihood of each origin would be complex (if possible at all), and, given the sample sizes, values in favor of a particular origin would be modest. Additionally, the close similarity of the Catalan and Ligurian general populations should be taken into consideration. For instance, two different Italian reference haplotypes from our sample match two Catalan Coloms, and another Italian control matches a Catalan control. We have shown that, although linked by their linguistic origin, Colombo and Colom are two surnames with very different histories that are reflected in the genetic diversity of their bearers, which offers a glimmer of hope for settling the dispute about Columbus’ origins. CONFLICT OF INTEREST The authors declare no conflict of interest. ACKNOWLEDGEMENTS We wish to express our gratitude to all donors, and to Professor Gabriella Girelli (University of Rome ‘La Sapienza’) and Ms Irene Contini (University of Rome ‘Tor Vergata’) for their cooperation in collecting the control north Italy samples. Funding for this research was provided by Malvarrosa Media – Valencia, Fundación M. Botı́n and University of Granada. Sampling of the Colom men was sponsored by ‘Fausto Producciones’. 1 De Yzaguirre L: Aproximació lexicomètrica a les interferències de base fonològica en els escrits autògrafs de Cristòfor Colom: La lengua materna de Cristóbal Colón. Eivissa: Consell interinsular d’Eivissa i Formentera, 2006. 2 Merrill CJ: Colom of Catalonia: Origins of Christopher Columbus Revealed. Spokane, WA: Demers Books, 2008. 3 King TE, Jobling MA: What’s in a name? Y chromosomes, surnames and the genetic genealogy revolution. Trends Genet 2009; 25: 351–360. 4 King TE, Jobling MA: Founders, drift, and infidelity: the relationship between Y chromosome diversity and patrilineal surnames. Mol Biol Evol 2009; 26: 1093–1102. 5 McEvoy B, Bradley DG: Y-chromosomes and the extent of patrilineal ancestry in Irish surnames. Hum Genet 2006; 119: 212–219. 6 Sykes B, Irven C: Surnames and the Y chromosome. Am J Hum Genet 2000; 66: 1417–1419. 7 Miller SA, Dykes DD, Polesky HF: A simple salting out procedure for extracting DNA from human nucleated cells. Nuclear Acids Research 1988; 16: 1215. 8 Mulero JJ, Chang CW, Calandro LM et al: Development and validation of the AmpFlSTR Yfiler PCR amplification kit: a male specific, single amplification 17 Y-STR multiplex system. J Forensic Sci 2006; 51: 64–75. 9 Gusmao L, Butler JM, Carracedo A et al: DNA Commission of the International Society of Forensic Genetics (ISFG): an update of the recommendations on the use of Y-STRs in forensic analysis. Forensic Sci Int 2006; 157: 187–197. 10 Excoffier L, Laval G, Schneider S: Arlequin (version 3.0): an integrated software package for population genetics data analysis. Evol Bioinform Online 2005; 1: 47–50. 11 Athey TW: Haplogroup prediction from Y-STR values using a Bayesian allele frequency approach. J Genet Geneal 2006; 2: 34–39. 12 Adams SM, Bosch E, Balaresque PL et al: The genetic legacy of religious diversity and intolerance: paternal lineages of Christians, Jews, and Muslims in the Iberian Penin- sula. Am J Hum Genet 2008; 83: 725–736. 13 Bandelt HJ, Forster P, Rohl A: Median-joining networks for inferring intraspecific phylogenies. Mol Biol Evol 1999; 16: 37–48. 14 Excoffier L, Lischer HEL: Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resources 2010; 10: 564–567. 15 Morral N, Bertranpetit J, Estivill X et al: Tracing the origin of the major cystic fibrosis mutation (DF508) in European populations. Nat Genet 1994; 7: 169–175. 16 Saillard J, Forster P, Lynnerup N, Bandelt HJ, Nørby S: mtDNA variation among Greenland Eskimos: the edge of the Beringian expansion. Am J Hum Genet 2000; 67: 718–726. 17 Sturrock K, Rocha J: A multidimensional scaling stress evalutation table. Field Methods 2000; 12: 49–60. Supplementary Information accompanies the paper on European Journal of Human Genetics website (http://www.nature.com/ejhg) The Y chromosome in Colom/Colombo men LJ Martı́nez-González et al 216 European Journal of Human Genetics http://www.nature.com/ejhg Surname and Y chromosome in Southern Europe: a case study with ColomsolColombo Introduction Methods Samples DNA extraction and genotyping Data analysis Figure 1 Populations and localities where ColomsolColombo men were sampled. Results Table 1 Descriptive statistics of the genetic diversity in the different samples and percent frequencies of estimated haplogroups Figure 2 (a) Multidimensional scaling plot based on FST distances among haplotypes. Figure 3 Median joining networks for the ColomsolColombo chromosomes in each estimated haplogroup. Discussion Figure 4 Median joining network for the estimated R1b chromosomes. Table 2 Major lineages found in the Colom/Colombo samples Table 3 Descriptive statistics of the Y-chromosome lineages in the different samples Conflict of interest ACKNOWLEDGEMENTS work_cipbr63bh5apvj2bjgpgp5dxp4 ---- J F M S E , 28(2), pp. 489~501, 2016. www.ksfme.or.kr 산해양 연구 권 통권, 28 2 , 80 , 2016. http://dx.doi.org/10.13000/JFMSE.2016.28.2.489 - 489 - 서 론. Ⅰ 우리나라 등 생들 역사를 주 역사 업 이나 역사 과 를 통해 가장 많이 습 는 것 나타난다(Moon, Jae-Kyung Jeong, Mi-Ran, ㆍ 이는 역사 업과 역사 과 가 생들 2015). 역사 습에 요 매체가 다는 것 양질, 역사 업과 과 개 이 요 다는 나타낸다 특히 생들에게 존 지식 소 자 . , 개 어 새 운 지식 생산자 창조 인 합인재가 것 요구 는 계 움직임 역사 (Cho, Soo-Hyun Park, Chang-Un, 2013)ㆍ 업과 과 개 에도 향 미 게 다. 근 내러티 를 용 역사 과 개 업에 심이 많 지고 있는 생들 에게 지식 생산자 역 권장 는 움직 임과 지 다 내러티 를 역사과에 용. 효과 여, VanSledright & Brophy(1992) 에 르면 생들이 구체 인 역사 , 5, 6 인 과 웅 심 이야 역사를 명 고, 역사 지식 내러티 구조 억 고 있 인 다(Kang, Sun-Joo, 2011). Barton & 생들 다양 역사 인Levstik(2004) 과 사건 자료 부 역사 지식 획득 , 한 미 등학교 역사교과서의 내러티 분석 소 대 대학( ) Analysis of Narratives of Elementary School History Textbook of Korea and US So-Young PARK (Daegu University) Abstract The purpose of this research is to analyze the narratives of elementary school history textbooks of Korea and US. The research problems are as follows. Firstly, what are the form and content of narratives of Korea's elementary school history textbook of Korea and US. Secondly, what are the characteristics of narratives of American elementary school history textbook of Korea and US. The content analysis method was utilized for analyzing narratives of textbooks. Research results are summarized as follows. Firstly, the features of Korea's elementary school history textbook are described. Secondly, the features of American elementary school history textbook are described. Thirdly, the common features and differences between both countries' textbook narratives are analyzed. Lastly, the implications for diversifying the narratives of Korea's elementary school history textbook are recommended. Key words : History Textbook, Narrative, Elementary School Corresponding author: 053-850-4364, syoungpark@daegu.ac.kr 2013 . - 490 - 보들 별개 것 들이는 것이 니라 미가 통 있도 구조 여 억 다고 보고 면 인 구조가 내러티, 라고 보 다(Kang, Sun-Joo, 2011). 이는 내러티 가 습자 미에 부합 고, 역사를 쉽게 이해 있게 며 역사 사실, 억 용이 고 사고를 가능 게 , 다는 장 이 강조 이다(Yu, Jeong-Mi․ 그 다면 내러티 란 어떤 것Choi, Yong-Gyu). , 인지에 자들 를 살펴볼 요가 있 다 는 러다임 사고 내러. Bruner(1986) 티 사고를 구분 여 러다임 사고가 논리 , 규 에 해 지 는 보편 인 식인데 해, 내러티 사고는 스토리 링 통 여 미를 획 득 는 식 는 것 소개 다(Kang, Hyun-Suk Kim, Kyung-Su Joint Translation, 2010). ㆍ 그리고 내러티 사고를 삶 를 다루는 상 황맥락 인 사고 인간 계에 이해 미 추구 는 것 사 다(Bruner, 루 내러티 사고는 논리 지식 1986). 획득과 달리 인간 삶에 이해 미, 가능 게 다. 내러티 범 를 사고 양식에 여 이야 결과 내러티 사고 양상, 내러티 커뮤니 이 내러, 티 명 도 다(Park, Min-Jeong, 2007). 이는 참여를 통 미구 과 계 , 상상 차원 통 지식 획득 구, 이 가능 내러티 를 강조 것이다. 내러티 를 나 구조 간주 는 견도 존 재 다 즉 내러티 란 이 어 사건들에 . , 미를 공 해 이야 같 태 조직 구조 이야 이며(Kang, Hyun-Suk et al., 내러티 를 통해 지식 구조 있2007). 나타낸다. 이러 들에 추어 볼 내러티 는 , 자 독자 참여를 허용 는 이야 이 며 계 상상 등 다양 차원 , , , 미 구 이 가능 이야 이며 삶 를 다루, 는 상황 맥락 인 사고를 미 다 특히 내러티. 를 용 역사과 특징 는 다 과 같이 시 다 에 르면. Jeong, Ji-Whang(2005) , 역사가 역사 인식과 해결 답 구 사료 내용 읽고 구 며 , 그 가 계를 논 역사 상상 사용, 여 연구 상 인 입장에 사고 내용 ( ) 담 자 이 명 히 드러나며 독자를 고, , 등이 역사 내러티 특징 시 다 는 내러티 특. Ahn, Jung-Ai(2007) 징 자 존재 구체 이고 인 사, , 인간 존재 시 다. 상 내러티 특징에 추어볼 특히 역사 과 에 시 는 내러티 는 다, 양 이야 장르를 용 있고 스트를 , 심 자 습자 참여가 가능 고 삶에 역사 상상 , , 있는 목소리를 담 있는 내러티 라고 있다 역사 인 과 사건 등 이야 를 . 자 목소리 없이 논리 이고 보편 인 식 명 다면 이는 내러티 간주 어 울 , 것이다. 등 역사과 내러티 여 내러티, 를 용 등 역사 업 효과(Lee, Ju-Yeonㆍ 내러티 식 용 Kim, In-Sook, 2014) 통 등 생 역사 사고 신장에 연 구 내러티 를 (Jeong, Ji-Whang, 2005), 용 등 역사 재 구 (Yu, Jeong-Mi Choi, ㆍ 등 연구가 행 있다Yong-Gyu, 2010). . 이 연구들 연구자가 내러티 를 자체 개 여 행 것 내러티 를 용함 써 생들, 과 미를 높이고 역사 사고 신장에 , 인 결과를 도출 것 나타난다. 생들이 역사를 공부 는 데 있어 가장 용 도가 높 매체는 과 이다 과 에 시 . 내용이 습자들 미 심 고 주 를 지속 집 시킬 있도 계열 있게 - 491 - 조직 어 있다면 사 욱 높, 질 것이다 라 행 (Won, Hyo-Heon, 2010). 우리나라 과 에 시 내러티 는 어떠 식과 내용 구 어 있고 어떠 특징 , 지니는지를 연구함 써 습자 역사 과 미 역사 사고 보다 높일 있는 마 요가 있다. 행 우리나라에 용 는 등 역사 2009 과 를 용 업 5 2 6 1 에 이루어진다 연구. Moon, Jae-Kyung(2015) 에 들이 가장 미를 보이는 시 가 5, 6 일 강 라는 결과에 주목 여 본 연구는 일, 강 가 담 역사 과 내러티 를 6-1 분 고자 다 본 연구에 는 우리나라 역사 . 과 내러티 를 분 해 미국 등 역사 과 내러티 를 병행 여 분․ 고자 다 이는 우리나라 역사 과 내러티. 를 보다 체계 이해 고 내러티 를 다양, 게 구 시사 도출 는 데 도움 이 있다고 단 이다. 본 연구는 국과 미국 등 역사 과 에 시 내러티 를 분 는 데 연구 목 이 있다 연구 는 다 과 같다. . 첫째 국과 미국 등 역사 과 에 , 시 내러티 식과 내용 어떠 가? 째 국과 미국 등 역사 과 에 , 시 내러티 사 에는 어떤 특징이 있는가? 본 연구는 국과 미국 등 역사 과 에 시 내러티 특징 분 함 써 우리나라 등 역사 과 내러티 특징, 상 이해 고 내러티 특징 좀 , 있는 과 개 시사 도출 다는 데 연구 가 있다. 연구 방법. Ⅱ 조사 상1. 이 연구에 는 국과 미국 등 고 역사 과 에 시 내러티 를 분․ 다 국 경우 개 과 에 른 사. , 2009 회과 과 를 상 며 특히 단6-1 , ‘2 원 근 국가 립 노 과 민족 운동 : ’ 분 다 미국 경우 출 사에 . Harcourt 상 Social Studies: The United States(2007) 며 를 , ‘Unit 2: Exploration and Settlement’ 분 다. 분석 거2. 미에 역사 내러티 는 역사 가리키지만 본 연구에 는 역사 과 , 내러티 를 다 과 같이 여 고자 다 내러티 란 이 이고 식 논리 인 지식. 명이 닌 이야 식 시 다, ‘ ’ 양 스토리에 부 인간 삶과 모든 이야 를 포 는 개 이다(Park, So-Young ․ Kim, Dae-Hyun, 2012). 내러티 과 내용 분 거 행연구(Park, So-Young Kim, Dae-Hyun, 2012)․ 에 여 다 과 같이 내러티 분 거 를 다. 내러티 식과 내용․ 내러티 사 특징․ 분석 방법3. 본 연구에 는 내러티 구 과 특징 분 해 내용 분 법 용 다 본 연구에. 는 내러티 범 에 다 항목들 외 다 연 지도 사진이나 삽 그림 그리고 . , , , , 과거 역사 름 논리 명 는 스트 스트 이해 도를 평가 는 질 등 외 다 본 연구에 는 역사 논리를 감소시. 키지 면 자 목소리가 보이는 만, 캐릭 이야 습자 감 이 담, - 492 - 이야 를 요구 는 동 습자에게 , 게 다가가는 다양 읽 자료 등 내러티 범 에 포함 다. 분석 결과. Ⅲ 한국1. 가 내러티 식과 내용. 본 연구에 분 단원 도입 소단원 개2 , 4 , 리 단계 구 다 단원에 시 내러티. 2 는 본 에 내러티 자 이야 만 , , 캐릭 질 상자 읽 자료 작 이야 , , 큰 역사 역사 능 등 구 었다, . Division Form Content Unit Introd uction Author's narrative Outline and Ask a Question Less on Introd uction Author's narrative Outline and Ask a Question Main Text Text Stimulate Student's emotion Caricature' s narrative Ask a Question or Give information Text box Reply or Enrich Text Small story, Big History Give a Question and reading materials Unit Last History Skill Give Problem-Solving Activities Forms and Contents of Narratives of Korea's Primary School History Textbook 나 내러티 사. 도입단계에 시 내러티 는 자가 본 내용 개 면 미를 고 핵심 내 용 내 는 질 어 있다 단원. 도입부에 시 내러티 는 다 과 같다. 세기말 우리나라는 개항을 요구하는 서양의 여19 러 나라와 일본의 침략을 받았다 우리 민족은 여. 러 방법으로 외세와 맞서 싸우며 항하 으나 무 력을 앞세운 일본에 나라를 빼앗겨 강압 인 식민 통치를 겪었다 우리 민족은 빼앗긴 나라를 되찾기 . 하여 어떤 노력을 하 을까? 세기에 조선은 나라 안 으로 어려움을 겪었다19 . 안으로는 세도 정치의 잘못으로 살기 어려워진 백 성의 기가 끊이지 않았고 밖으로는 서양과 일본, 의 세력이 조선을 하기 시작하 다 이에 조선. 은 세도 정치의 잘못을 바로잡고 서양과 일본의 세력을 막아 내려고 노력하 다 조선은 서양과 일. 본의 세력을 어떻게 막아 내려 하 을까 조선이 ? 개항할 수밖에 없었던 까닭은 무엇일까? 사 는 단원 시작 는 단계에 자가 해당 단원 내용 개 면 습자가 습, 해야 는 핵심 내용 내 는 질 시 것이다 이는 자 사고 름 보여주 . 에 습자들도 역사 사고를 모델링 있, 는 회를 공 다. 그리고 단원과 소단원 도입 내러티 뒤에 는 주 습 내용이 명 다 주 . 습 내용 가장 많 차지 는 것 본 이다 본 내용 에 자가 . 이야 를 건 는 식 었거나 자 사 고 과 이나 가 단이 드러나거나 습자 , 를 자극 거나 습자가 이야 를 도 부분 내러티 간주 고 분 다. 만 캐릭 이야 나 상자 작 이야 큰 , 역사 등 외 본 내용 부분 내, 용 자 목소리 없이 과거 사건들 명 는 태 어 있다 그러나 일부 내용에. 는 감 인 단어들 사 며 습자 를 자극 있는 부분들이 나타났다 특히 나. ‘ 라를 찾 노 단원에 해당 사 들 ’ 찾 볼 있었다. 헌병 경찰에게 체포된 독립운동가들은 고문을 받 다 죽기도 하 다 살아남아도 감옥에 갇 질병과 . 노동 배고픔에 시달렸다, . (p. 88) 토지 조사 사업 이후 많은 농민이 비싼 토지 사용 료를 내고 농사를 지어야만 했다 비싸진 토지 사. 용료와 늘어난 세 때문에 농민의 생활은 더욱 어려워졌다. (p. 89) - 493 - 도시로 일자리를 구하러 간 사람들도 가난한 생활 을 하 다 일본인이 경 하는 회사에서 은 임. 을 받으며 하루 시간이 넘는 힘든 일을 하 다12 . 일자리를 구하기 힘든 사람은 날품을 팔거나 구걸 하며 먹고살았고 주로 도시 주변 토막집에서 살았, 다. (p. 89) 사 들에 나타난 질병과 노동 고‘ , 에 시달 다 농민 생 욱 어 워 다’, ‘ ’, 루 시간이 는 힘든 일 다 등 ‘ 12 ’ 자 감 어 볼 있다 롭고 . 고통스러웠 삶에 자 감 이 담 습자에게 역사 감 이입 가능 공 다. 다 만 캐릭 이야 상자 읽, 자료 작 이야 큰 역사 등 내러티 가 , ‘ ’ 있다 만 캐릭 이야 사 들 다 과 같. 다. 강화도 조약은 왜 불평등 조약일까요? ․ 박규수가 일본 서양 세력과 통상해야 한다고 ․ 주장한 까닭은 무엇일까요? 최익 이 일본 서양 세력과 통상하는 것을 반․ 한 까닭은 무엇일까요? 근 문물이 들어와서 편리해진 은 무엇일까․ 요? 일제는 놋그릇 가마솥 농기구와 같이 속으로 , , ․ 된 생활 도구까지 빼앗아 갔습니다. 사 들 근 만 캐릭 를 용 여 습자가 생각해볼 질 시 거나 본 과 , 보를 공 는 태들이다 습자는 . 만 캐릭 질 과 이야 를 통해 보다 재미 있고 생생 게 습 있 며 만 캐릭 가 , 시 는 질 에 답 해 답 찾 는 사 고 동 게 다. 상자 읽 자료들 만 캐릭 질 에 답 있는 내용이나 본 내용 보충 심, 있는 내용들이 많다 그 사 는 다 과 . 같다. 강화도 조약의 주요 내용․ 서양 통상에 한 찬반의 입장 ․ 단발령에 한 찬성과 반 의 입장․ 근 문물 기차 화 차( , , )․ 일본의 독도 강탈․ 조선 태형령․ 한국 복군 창설․ 오동 투 청산리 첩 이 창 의거 윤 길 , , , ․ 의거 일제 강 기 어느 학생의 생활 일제 강 기 국, ․ 어학자의 항 역사학자의 항, 사 에 찬 입장에 는 양 통상과 단 에 내용이 있 며 습자, 여 찬 견 내도 함 써 역사 가 단 회를 공 다 그리고 일본 . 독도 강탈과 조 태 국 복군 창 이, 내용들 나라를 지키고 찾 노 보여 다 상자 읽 자료들 만 캐릭. , 질 에 답 있는 내용 구 경우 목 식 가지고 읽도 었 며 읽 , 자료 보를 포함 고 있어 습자 미 내용 이해에 도움 있 것 이다. 작 이야 큰 역사 내러티 는 목 질‘ ’ 태 시 고 내용 사진이나 삽, 등과 함께 고 있다 보통 소단원별 . 개 시 어 있 며 만 캐릭 나 상자1~2 , 를 많이 용 소단원에 는 생략 도 다. 작 이야 큰 역사 내러티 목 는 ‘ ’ 다 과 같 사 가 있다. 조선왕조의궤는 왜 랑스에 있었을까․ 안 근이 이토 히로부미를 격한 까닭은 무엇일․ 까 유 순이 고향에서 만세 시 를 벌인 까닭은 무․ 엇일까 이회 과 그의 형제들이 만주로 간 까닭은 무엇․ 일까 윤동주는 어떻게 독립운동을 하 을까․ 작 이야 큰 역사 에 목 시 ‘ ’ 질 들 주 인 다루고 있 며 (Why), 엇 어떻게 등 포함 고 있어 (What), (How) 습자 다양 사고를 허용 다 작 이. - 494 - 야 큰 역사에 포함 내러티 에는 질 에 답 있는 내용 읽 자료뿐만 니라 질 상 실 사진 그림 건축 작품 시, , , ( ) 등도 포함 어 있어 척 미 운 습이 가 능 것 보인다. 역사 능 내러티 는 습자 해결 동 다 본 연구에 분 단. 원에 는 역사 능 시사만평 읽 를 시‘ ’ 며 단계 동 있도 었다, 4 . 시사만평이란 무엇일까․ 시사만평은 어떻게 읽어야 할까․ 질문에 답하며 시사만평을 읽어 보자․ 시사만평을 스스로 읽어 보자․ 시사만평 읽 에 는 만 캐릭 질 ‘ ’ 통해 습자 다양 이해 해 가능 게 다 습자 경험이 경이 는 이야 를 도. 출 있는 내러티 라 있다. 다 내러티 특징. 우리나라 등 역사 과 에 시 내러티 특징 다 과 같이 시 있다. 첫째 단원 도입 주 습 리 단계에 , , , 골고루 내러티 를 용 다. 째 자 목소리 타인 목소리를 들, 써 미 핵심 내용 이해에 도움이 있는 내러티 를 용 다 단원 도입 . 내러티 는 자 목소리를 통해 본 내용 개 고 핵심 내용 있는 질 시 었 며 다양 만 캐릭 타인 이야, ( ) 를 통해 습자가 만 캐릭 를 나 면 습 내용에 근함과 이해도를 높일 있도 다. 째 습자 목소리를 들 있는 질 , 시 고 질 에 답 있는 내용 담 내, 러티 를 용 다 상자 읽 자료 경. 우 만 캐릭 가 시 는 질 에 답 있도 내용이 구 었다 작 이야 큰 역사 는 . ‘ ’ 엇 어떻게를 는 질 과 그에 답 있, , 는 내용 시 고 있다. 째 습자 산 사고를 개 있는 , 내러티 를 용 다 리 단계 역사 능. 에 용 내러티 는 습자가 다양 상상과 택 있게 함 써 습자 산 사 고 개 는 데 도움이 있다. 미국2. 가 내러티 식과 내용. 본 연구에 분 단원 개 단(Unit) 3 원 구 어 있고 단원 개 (Chapter) , 3~4 소단원 구 다 단원 도입과 (Lesson) . 소단원 도입 본 리 단계에 시 내러, , 티 태는 다 과 같다. Division Form Content Unit Introd uction Practice Read the paragraphs, and identify details that support the main idea Apply Read the paragraphs, and answer the question Start with a Journal The log of Christopher Columbus Less on Introd uction You Are There History including reader Main Text Text Narrative Text Biography Presented in most of the lesson C h i l d r e n in History Dipending on the lessonPoints of View Review Critical Thinking Write A Scene Cha pter Last Critical Thinking Present questions Unit Last Critical Thinking Present questions Activities Writing, Project, Read More, Online adress
Forms and Contents of Narratives of American Primary School History Textbook - 495 - 나 내러티 사. 단원 도입부에 시 ‘Practice’ ‘Apply’ 는 소개 고 용 도 는 내러티 이Skill 다 에 는 소개 며 에. ‘Practice’ ‘Skill’ , ‘Apply’ 는 이를 용해보는 시간 갖게 다 본 연. 구에 분 단원에 시 능 핵심 이 어 이를 명 는 구체 인 사실들 인 는 것이다 이 능 익히 해 라는 미. Taino 국 원주민 소재 읽 자료를 시 다. 그리고 이어 시 는 는 ‘Start with a ~ ’ 시 이야 등 시작 는 내러티 이다, , . 이 단원에 는 시작 며 럼버스 행, 소개 다 월 일 월 일 월 . 1492 9 9 , 10 11 , 10 일 담고 있 며 덧붙여 가지 12 , 질 시 다 나 질 핵심 이 어. 구체 사실 인 는 질 이며 나 , 질 습자에게 럼버스가 했 것과 같 여행에 도 있겠는지 닌지 그 이 를 생각해보도 는 질 이다. 각 소단원 여러분이 거 에 있다‘ (You are 시작 는데 이는 습자가 당시 상황 there)’ , 속에 살고 있다고 가 이야 이다 를 들면 . 다 과 같다. 년 월이다 는 한 달 넘게 바다에 있다 앞1497 6 . . 서 는 국에서 콜럼버스의 탐험에 해 듣고 이 여행을 하기로 서명을 했다 그러나 지 는 . , 다시 생각하기 시작했다 안개가 배 주변에 자욱하. 다 탑승한 부분의 사람들은 걱정하는 듯이 보인. 다 한 승무원은 차가운 공기가 뼛속까지 춥게 . ‘ 한다 고 말한다 는 안개 속을 들여다보려고 애’ . 를 쓰지만 소용이 없다 밖의 모든 것이 불안스럽. 다. (p. 118) 년이다 는 아래에 거 한 만이 내려다보이1650 . 는 언덕 에 서 있다 두 달 에 는 국에서 . 배를 타고 메릴랜드 식민지로 왔다. 땅은 사람들로 북 거리는 런던의 거리와 매우 다 르게 보인다 담배 밭과 다른 농작물들이 시선이 . 머무는 데까지 펼쳐진다 는 런던에서 직장을 구. 할 수 없었기 때문에 메릴랜드에 왔다 주변을 둘. 러보았을 때 는 많은 일을 하게 될 것이다, . (p. 194) 사 들 과거 상황 속에 습자를 면 습자 여 마 역사 속 인, 이 것처럼 느끼게 다 이는 일종 타임. 신과 같 장 이다 습자들 여러분이 거. ‘ 에 있다 라는 타임 신 타고 과(You are there)’ 거 시간 여행 게 다. 편 본 내용 역사 사실 명 는 , 내용 이외에 내러티 태 부분들 살펴볼 있었다 이는 자 목소리를 . 이었다 를 들면 탐험 즈니스 간주. , 면 험과 보상 업가 등 용어를 사용‘ ’, ‘ ’ 여 부분이 있다. 탐험가들은 기업가가 되어야 했다 그들은 기업가. 가 사업을 개시하고 운 하는 것처럼 탐험을 계획 하고 실행했다 흔히 탐험가들은 뭔가를 성취하고 . 얻기 해 기울여야 하는 노력과 비용이 탐험의 모험 가치가 있다는 것을 다른 사람들에게 설득시 켜야 했다 선박과 물품들은 상당한 비용을 필요로 . 했다 한 많은 험들이 있었다 를 들면 배가 . . , 가라않을 수가 있고 탐험가가 값비싼 물품들을 발, 견하지 못할 수도 있었다. (p. 112) 사 에 특히 히 탐험가들 가‘ 를 취 고 얻 해 울여야 는 노 과 용이 탐험 모험 가 가 있다는 것 다른 사람 들에게 득시 야 했다 는 장 탐험가 자’ 질 는 역 에 자 목소리가 것 볼 있다. 본 에 나 주 상황 인 등 를 ( , ) 여러 단에 걸쳐 내러티 들이 있다. 를 들면 에 는 럼버스 , Chapter 3 Lesson 2 다른 탐험가들 항해 탐험 심 변 는 계를 상 게 사 다 . Chapter 4 에 는 청 도들 이 라워 항Lesson 3 해 약에 여 구체 사 다 나. 소단원 동일 주 래 각 단들이 계 속해 이어지는 이야 구조 어 동일, 상이 주어 는 목 어 복 여 시 다 사 이 라워 약에 단 . - 496 - 다 단 구 다 일부를 시 면 다. 과 같다. 메이 라워는 버지니아를 향했지만 폭풍이 불면서 , 배를 코스에서 벗어나게 했다 신에 메이 라워. 는 지 매사추세츠인 에 상륙했다Cape Cod . 정착자들은 정부가 없는 곳에 도착했다 질서를 지. 키기 해 메이 라워에 탑승한 모든 사람들은 서 약 는 정에 서명했다 이 문서는 메이 라워 . 서약으로 알려지게 되었다 서명자들은 공정한 법. 이 식민지의 선을 해 만들어졌다는 데 동의했다. 그들은 이 법을 수하기로 약속했다. 메이 라워 서약은 서명한 사람들에게 그들 스스 로를 통치할 수 있는 권리를 주었다 군주가 통치. 하던 시 에 셀 정부는 매우 새로운 아이디어- 다 한 메이 라워 서약은 다수의 규칙이라는 . 아이디어를 포함했다 과반수의 사람들이 어떤 법. 이나 결정에 동의한다면 모두가 그것을 따라야했, 다. (p. 160) 사 는 이 라워 약에 개 과 본 지식 간단히 달 고 마 는 것이 니라 이 라워 약이 등장 게 경에, 부 약 특징에 이르 지 여러 단에 걸 쳐 구체 이야 다 이는 나 주 를 . 구체 인 이야 느껴지게 는 목이라 있다. 경우 부분 소단원에 (Biography) 시 는데 이는 쪽 분량 작 었다 본 , . 연구에 분 단원 들 신뢰 존경, , 책임 공 돌 국 가지 가 를 다루고 , , , 6 있 며 나 에 나 가 가 었, 다 시 들 다 인 삶 통해 . 주요 가 를 다룬다. 노 로 팔려간 아 리카인 고용주의 요Estevanico( , 구에 의해 북미를 탐험하던 에 사망 신뢰성 )_ (p. 133) 북미 원주민들의 삶을 개Bartolom de Las Casas(é 선하기 해 노력한 최 의 유럽인 책임 )_ (p. 151) 추장의 딸 정착민들과의 평화 계Pocahontas( , 를 형성 돌 )_ (p. 157) 종교 자유를 해 투쟁하다 미Anne Hutchinson( 국 원주민의 공격에 의해 사망 공정함 )_ (p. 185) 건 를 살펴보면 억울했지만 주인 신4 , 뢰를 얻어 모험 인 삶 살 노 원주민 , 해 책임감 가지고 행동했 럽인 착민, 에게 도움 주면 평 운 계를 만들었 원주민 추장 모 에게 공 종 자, 를 해 일 다가 원주민 공격 사망 럽인 등 삶이 이야 었 있다 이 . 들 노 럽인 원주민 등 다양 사회 , , 지 인 들 다루고 있 며 신뢰 책임 돌, , , 공 함 등 가 를 직 내 우면 , 인 들 삶 개 다 그리고 각 이야 . 마지막에는 생들이 생각 있는 질 시 는데 이는 가 담고 있는 신뢰 책임, , , 돌 공 함 등 가 들 생각해보도 요구, 다 에 포함 질 들 다 과 같다. . 의 행동은 어떻게 그가 신뢰받을 수 있Estevanico․ 었다는 것을 보여주었는가? (p. 133) 는 북미 원주민들의 우Bartolom de Las Casas․ é 를 한 책임감을 어떻게 가졌는가? (p. 151) 의 행동은 어떻게 그녀가 타인을 돌보Pocahontas․ 았다는 것을 나타내는가? (p. 157) 은 어떤 에서 공정하게 처리하Anne Hutchinson․ 기 해 투쟁했는가? (p. 185) 질 들 를 읽고 가 도 가, 에 해 해당 인 삶과 지어 생각 있는 시간 습자에게 공 다. 다른 내러티 는 역사 속 이들‘ (Children in History)’, ‘ (Points of View)’, ‘ 사고 등이 있다 역사 속 이들’ . ‘ ’ 에 는 럼버스 탐험에 동승 원들 명인 소 를 소개12 Diego Bermúdez 다. 략 디에고는 배에서 가장 낮은 지 의 사환이... 었다 사환은 부분의 선원들이 하고 싶어 하지 . 않는 일 를 들면 요리 세탁 시간을 확인하는 , , , , 일 등을 한다 디에고는 분짜리 유리를 이용해서 . 30 시간을 확인했다 디에고는 모래가 유리의 바닥까. - 497 - 지 모두 떨어지는 분 간격으로 벨을 울리고 짧30 은 기도를 외쳤다 모든 사람들은 그의 행동을 통. 해 시간을 알 수 있었다. 여러분은 집이나 학교에서 어떤 일을 해야 하는 가? (p. 114) 사 에 는 생들 래 과거 인 에 해 이야 면 재 삶 생각 있는 질 시 다 이러 질 통해 생들 . 과거 재를 지 있게 다. 인 에 내러티 가 태 만 ‘ ’ 시 는 것 니다 본 에 도 인 에 이. 야 가 자주 는데 이 는 가 추구했, ‘ ’ 것처럼 가 짓 보다는 탐험과 착, 과 에 맞추어 다. 이라는 목 내러티‘ (Points of View)’ 는 럼버스 탐험에 가지 시 뒤에 개 질 시 다 나는 요약, . 는 질 이고 나는 재 과거를 지, 있는 질 이다. 아메리카 원주민 리더 콜럼버스의 도착은 처음: ① 부터 재난이었다 그는 즉시 카리 섬의 인. ... 디언들을 노 로 만들기 시작했다. 교사 작가 콜럼버스 항해의 주요한 장기 인 : ② 요성은 그것이 측할 수 없었던 규모로 세 상의 사람들을 섞어 놓았고 미국이 인종 으로 , 가장 다양한 사회가 되는 과정을 발시켰다. 교사 작가 콜럼버스가 도착했을 때 히스 니: , ③ 올라 섬에 많은 타이노족이 살았음에도 불구하 고 그들 수의 격한 감소는 유럽 계약의 가장 , 놀라운 즉각 인 향이었다. 이 여러분 차 요약하기․ 련짓기 여러분과 친구는 왜 하나의 사건이나 . ․ 아이디어에 다른 을 가지는가? (p. 125) 사 에 는 럼버스 탐험 가지 시각 이해 보다는 가지 이상 시각, 이 있 있다는 습자에게 보여 다. 그리고 습자 스스 차이에 해 인식 있는 질 시 다. 다 는 소단원 리 단계에 시 는 사고 쓰 내러티 를 들 있다‘ ’ ‘ ’ . 사고 경우 소단원 단원 단원 ‘ ’ , , 리 단계에 모 시 다 소 단원에 . , , 시 사고 질 가지 시 면 ‘ ’ 다 과 같다. 소단원 여러분은 남부 식민지에 환 작물이 없: ․ 었다면 노 제도가 성장했을 거라고 생각합니 까 설명하세요? . (p. 201) 단원 무역과 기술은 탐험의 성장에 어떻게 : ․ 요한 역할을 하 는가? (p. 143) 단원 여러분이 뉴잉 랜드 식민지에서 성장했: ․ 다면 여러분의 삶은 어떻게 달라졌을 것이라고 , 생각하는가 동 식민지에서 성장했다면 남부 ? ? 식민지에서 성장했다면? (p. 207) 소단원과 단원에 시 사고 질‘ ’ 과 지식 용 여 분 이고 인 사고를 것 요구 다 면 단원에 시 . , 사고 질 분 이고 질 에 ‘ ’ 추가 여 습자 상상 요구 는 질 이 시 다 그리 여 습자들 상상 여 . 시간 여행 고 그 여행 결과에 해 이야, 를 풀어가야 다 시간 여행 경우 도입 부. , 분에 시 여러분 거 에 있다 를 통해 도 ‘ ’ 가능했는데 도입 부분에 는 시간 여행 는 , 것 간주 만 면 지만 단원에 시, 사고 질 상상 도 요 구 다는 에 차이가 나타난다. 쓰 경우 생들에게 상상 고 탐구 ‘ ’ , 것 요구 다 를 들면 스페인 원과 타이노 . , 리 간에 이루어지는 짧 를 쓰도 거 나 탐험가 함께 여행 는 것처럼 상상(p. 115), 여 여행 일지를 쓰도 다거나 스페(p. 132), 인이 임 를 부여 이 에 해 조사 여 짧 보고 를 쓰도 다거나 매사 에 (p. 150), 착 사람인 것처럼 가 고 국에 있는 구에게 편지를 쓰도 는 쓰 등이 (p. 184) - 498 - 있다 이는 생들 다양 지식과 등 . 내러티 가 담 쓰 가 있다. 단원 리 단계에 는 를 통해 ‘Activities’ 습 것 도 는 동들이 시 다 이는 쓰 트 구 다. ‘ ’ ‘ ’ . ‘ 쓰 경우 북미 새 운 식민지 착자들’ 도 득 는 고를 쓰도 며, ‘ 트 는 북미 탐험과 식민지 에 해 시’ 는 만들도 다. 다 내러티 특징. 미국 등 역사 과 에 시 내러티 특징 다 과 같이 시 있다. 첫째 과거 재를 지 있는 내러티, 들 다양 태 용 다 소단원 도. 입부에 시 여러분이 거 에 있다 는 습자‘ ’ 가 시간여행 있도 며, ‘ ’, 역사 속 이들 등 내러티 에 도 ‘ ’, ‘ ’ 읽 자료 질 통해 습자 여 재 삶 찰 있는 회를 공 다. 째 시민 요소라 있는 가 들 , 내러티 에 직 다 본 연구 단. 원에 는 신뢰 책임 돌 공 함 등 가 를 , , , 내러티 지어 시 다. 째 본 핵심만 시 는 객, 언어뿐만 니라 자 견이나 가 가 포함 내러티 구체 이야 를 풀어가 는 내러티 를 용 다 탐험가를 업가 . 사 는 사 를 통해 과거 인 과 재 인 연속 상에 있게 며 나 , 사건 이 닌 여러 단에 걸쳐 자, 게 함 써 역사를 쉽게 이해 있게 다. 째 부분 내러티 는 읽 자료 함께 , 생들 목소리를 내도 는 질 시 다 이 질 들 요약 는 질 분 사고. , 상상 요 는 질 과거 재를 짓, 는 질 들이었다. 다 째 다양 장르 내러티 를 용 다, . 편지 보고 등 , , , , , 내러티 를 시 거나 습자가 직 만들어 , 내도 요구함 써 다양 인지 를 가능 게 다. 논의 결론. Ⅳ 본 연구는 국과 미국 등 역사 과 에 시 내러티 를 분 는 데 있다 본 . ․ 연구 결과를 통해 양국 과 에 시 내 러티 특징 이해함 써 내러티 특징, 보다 잘 살릴 있는 과 개 시사 고자 다. 우리나라 등 역사 과 경우 단원 도, 입 주 습 리 단계에 내러티 를 골고루 , , 용 며 자 만 캐릭 목소리를 , 내는 읽 자료 심 내러티 습자 목소, 리를 내도 요구 는 질 태 내러티 , 습자 를 자극 는 스트 산 사고를 , 요 는 내러티 등이 용 었다. 미국 등 역사 과 경우 과거 재를 , 지 있는 내러티 시민 가 를 , 직 내러티 이야 태 자, 게 풀어가는 내러티 스트 질 포함, 함 써 생들 다양 사고 과 상상 도 내러티 다양 장르 내러티 , 등이 용 었다. 우리나라 미국 내러티 사 를 통해 나타난 공통 과 차이 다 과 같다. 첫째 과 도입 단계에 내러티 가 , 용 다는 이 공통 나타난다 우리나라 . 경우 도입 단계에 자 목소리가 담 내용 개 과 핵심 내용 시사 는 질 태 내러 티 를 시 다 역사. Jeong, Ji-Whang(2005) 가 역사 인식과 해결 답 구 여 것 강조 있는데 도입 단, - 499 - 계에 내러티 는 이러 특징 다고 있다 미국 과 도입 단계에 는 . 습자가 마 과거에 존재 는 것처럼 사 내 러티 를 용 다는 에 우리나라 도입 단계 내러티 차이가 있다. 우리나라 도입 내러티 에 는 자가 습 자를 과거 시간 속 내 는 듯 느낌 주며 각 단원에 습해야 핵심 내용이 , 엇인지를 있게 면 미국 경우에는 , 습자가 마 과거에 존재 는 것처럼 사 읽 자료를 시함 써 습자 여 역, 사 감 이입 가능 높일 있 것 보인다는 에 차이가 있다. 째 읽 자료 질 함께 시 내러티, 를 용 다는 이 공통 나타난다. 우리나라 경우 질 시 고 읽 자 료를 시 경우가 많고 미국 경우 읽 자, 료를 시 고 질 마지막에 경 우가 많다는 에 차이가 있다 질 . 시 경우 질 에 답 목 식 가 지고 자료를 읽게 다는 에 미가 있다. 그리고 자료 에는 질 에 답이 부분 시 어 있다. 그런데 미국 경우 질 에 답 해 는 , 읽 자료에 시 내용 탕 약간 추 과 상상 해야 다. Jeong, Ji-Whang 역사 상상 보여주는 내러티 (2005) 용 있다 우리나라 과 에도 . 습자 역사 상상 요구 는 내러티 가 존재 다 를 들면 습자가 일 강 에 . , ‘ 살고 있다면 독립 여 어떤 일 있 지 생각해보도 는 내러티 가 있(p. 100)’ 다 미국 과 경우 과거 재를 지어 . 상상해보도 요구 는 질 이 자주 용 다. 째 본 스트 에 객 뿐, 만 니라 자가 이야 는 내러티 부분이 공통 나타난다 우리나라 경우 . 주 습 본 내에 상자 이나 만 캐릭 읽 자료 등 태 내러티 를 시, 는 경우가 많고 본 스트 에 는 , 부분 자 목소리가 나타나지 채 간략 명식 다 그러나 일부 소단원에 는 . , 자 견과 가 가 포함 내러티 가 용 도 다 면 미국 경우 자 견이나 . , 가 가 포함 과 이야 를 구체 풀어 나가는 이 많이 용 다는 차이가 있었다. 연구자들 역사 이 추상 이고 객 인 자 를 강조 뿐만 니라 생들 여 , 과 내용 부 일 거리를 지 게 는 객 언어 시 며 단락들 사이에 일‘ ’ , 이 부족 다고 지 다(Ahn, Jung-Ai, 2007). 우리나라 경우 페이지에 다양 상황이 사 어 각 단마다 다른 내용 명 는 경우 가 많고 단이 명이 나는 경, 우가 있다 면 미국 과 에 는 나 내. , 용 여러 단에 거쳐 구체 이야 는 차이가 나타난다 우리나라 경우 과 지면 . 약 단가 인해 페이지에 많 내용이 담겨 가능 도 있 것 추 다. 째 역사 능 내러티 가 공통, 용 었다 우리나라 경우 리 단계에 . 역사 능 다루는 내러티 를 용 는 면, 미국 경우에는 도입 단계에 역사 능 다 루는 내러티 가 있게 다루어진다는 에 차이가 있다 미국 경우 리 단계에 도 . 사고 같 역사 능 요 는 질 용 는 지만 도입 단계에 역사 능 , 내러티 용이 많 편이다 역사 . 능 내러티 가 도입 단계에 시 경우, 본 습 는 동 역사 능 용 있 다는 에 미가 있다 면 우리나라 같이 . , 역사 능 내러티 가 리 단계에 시 경우 해당 단원 습이 난 후 내용 이, 해 고 리 는 데 도움 있다. 다 째 역사 인 에 내러티 를 공통, - 500 - 용 다 우리나라 경우 상자 이. ‘ ’ 나 작 이야 큰 역사 등 용 여 나라를 ‘ ’ 해 쓴 인 들과 당시 생 삶에 이야 가 시 었다 미국 경우 를 통해 노. ‘ ’ 럽인 원주민 등 삶에 이야 를 , , 시 다 편 우리나라 경우 역사 인 에 . , 내러티 를 통해 역사 사건 인 에 이해 간 인 감 이입 가 것 는 면 미국 경우 를 통해 신뢰, ‘ ’ , 존경 책임 공 돌 국 등 시민 , , , , 요소를 직 시 다는 에 차이가 있다. 이는 사회과 역사과 격과 과 목 차이에 롯 었 있다 우리나라 . 사회과 목 에 르면 사회과는 민주 시민, 「 」 자질 갖추는 데 있고 등 과 에 , 시 역사과 목 는 인간 삶에 이해 「 」 목 키우는 과목 고 있다(MOE, 미국 사회과를 과 2015). 「 」 에 르면 사회과는 시민 향상시키 해 , 과이고 미국사를 과 , 「 에 르면 역사과는 시민 함양 목, 」 다 미국 경우 (Joo, Woong-Young, 2010). 역사과 사회과 목 마찬가지 시 민 함양 우 에 를 통, ‘ ’ 해 시민 가 를 고자 것 이 해 있다. 본 연구를 통해 내러티 를 용 과 개 시사 다 과 같이 도출 있었 다 첫째 과거 재를 짓는 내러티 를 . , 극 용 는 고 요가 있다. 과거에 미를 느끼고 공감 면 습 해 는 과거 재를 지어 생각 있는 다 양 내러티 용이 요 다 재 우리나. 라 과 에도 과거 재를 짓는 내러티 가 용 고 있 므 향후 읽 자료나 질, , 습자 동 등과 같이 다양 태 내러티 를 통해 습자가 과거 재를 지 있 는 회를 는 고 요가 있다. 째 역사 능 다루는 내러티 를 본, 에 용 있도 조직 는 고 요가 있다 재 우리나라 과 에도 역사. 능 다루는 내러티 가 어 있지만, 리 단계에 시 고 있어 본 내용 습 면 용 에 어 움이 른다 컨 역. , 사 능 다루는 내러티 를 도입 단계에 다면 해당 단원 습 는 동 역사 , 능 용 가능 이 높 질 것 상 다. 요컨 역사 능 내러티 를 본 에 용 , 있도 조직 는 고 요가 있다. 째 등 역사 이 사회과 , ‘ 역사 습 격 지향 있도 내러티’ 를 용 는 고 요가 있다 입시 . 주 역사 습이 니라 사회과 역사, 습이 해 는 특히 민주 시민 권리 책 를 진 있게 들이도 도울 있는 내러티 용이 요 다 라 역. 사 통해 사회과가 추구 는 민주 시민 자질 함양 는 데 여 있도 민주 시민 양 가 요소를 다루는 내러티 를 용 는 고 요가 있다. 째 본 함에 있어 자가 이야, 는 식 내러티 를 보다 있는 이 요 다 자가 이야 는 내러티 는 내. 용에 장감 공 있 이다. 지면 에 과 가 다루어야 , 내용 모 다루 해 는 간결 명이 욱 효과 일 있다 그러나 과 . , 지면이 라면 자 이야 를 라인 , 공 고 해당 라인 주소를 과 에 소개 는 도 고 있 것이다. 본 연구는 과 를 심 내러티 특징 들 분 에 실 업 장면에, ․ 이루어지는 과 내러티 용에 부분 다루지 못 다 후속 과 에 . 시 내러티 를 업에 어떻게 용 는지 - 501 - 에 연구를 행 요가 있다 본 연. 구에 는 내러티 포 인 특징 심 분 에 역사 사고 능과 내러티 를 , 지어 분 지는 못 다 라 후속 연. 구를 통해 역사 사고 능 함양 균 내러티 개 연구 요가 있다. 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Received : 15 March, 2016 Revised : 08 April, 2016 Accepted : 11 April, 2016 work_clitb7fevbh6vmkdkomdjkquyq ---- wp-p1m-39.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-39.ebi.ac.uk no 218201833 Params is empty 218201833 exception Params is empty 2021/04/06-02:09:28 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. Message ID: 218201833 (wp-p1m-39.ebi.ac.uk) Time: 2021/04/06 02:09:28 If you need further help, please send an email to PMC. Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_cnnufo55mzfnvmzjdoyvkjs7ze ---- wp-p1m-39.ebi.ac.uk Params is empty 404 sys_1000 exception wp-p1m-39.ebi.ac.uk no 218198756 Params is empty 218198756 exception Params is empty 2021/04/06-02:09:24 if (typeof jQuery === "undefined") document.write('[script type="text/javascript" src="/corehtml/pmc/jig/1.14.8/js/jig.min.js"][/script]'.replace(/\[/g,String.fromCharCode(60)).replace(/\]/g,String.fromCharCode(62))); // // // window.name="mainwindow"; .pmc-wm {background:transparent repeat-y top left;background-image:url(/corehtml/pmc/pmcgifs/wm-nobrand.png);background-size: auto, contain} .print-view{display:block} Page not available Reason: The web page address (URL) that you used may be incorrect. Message ID: 218198756 (wp-p1m-39.ebi.ac.uk) Time: 2021/04/06 02:09:24 If you need further help, please send an email to PMC. Include the information from the box above in your message. Otherwise, click on one of the following links to continue using PMC: Search the complete PMC archive. Browse the contents of a specific journal in PMC. Find a specific article by its citation (journal, date, volume, first page, author or article title). http://europepmc.org/abstract/MED/ work_cqv564wo5je4pdvm6frexbe7da ---- esj020 107..113 Iberian Origins of New World Horse Breeds CRISTINA LUÍS, CRISTIANE BASTOS-SILVEIRA, E. GUS COTHRAN, AND MARIA DO MAR OOM From the Centro de Biologia Ambiental, Departamento de Biologia Animal, Faculdade de Ciências, Universidade de Lisboa, Edifı́cio C2-Piso 3, Campo Grande, 1749-016 Lisboa, Portugal (Luı́s, Bastos-Silveira, and Oom); and the Department of Veterinary Science, University of Kentucky, Lexington, KY 40546-0099 (Cothran). E. G. Cothran is now at the Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843. Address correspondence to C. Luı́s at the address above, or e-mail: cmluis@fc.ul.pt. Abstract Fossil records, archaeological proofs, and historical documents report that horses persisted continuously in the Iberian Peninsula since the Pleistocene and were taken to the American continent (New World) in the 15th century. To investigate the variation within the mitochondrial DNA (mtDNA) control region of Iberian and New World horse breeds, to analyze their relationships, and to test the historical origin of New World horses, a total of 153 samples, representing 30 Iberian and New World breeds, were analyzed by sequencing mtDNA control region fragments. Fifty-four haplotypes were found and assigned to seven haplogroups. Reduced levels of variation found for the Menorquina, Sorraia, and Sulphur Mustang breeds are consistent with experienced bottlenecks or limited number of founders. For all diversity indices, Iberian breeds showed higher diversity values than South American and North American breeds. Although, the results show that the Iberian and New World breeds stem from multiple origins, we present a set of genetic data revealing a high frequency of Iberian haplotypes in New World breeds, which is consistent with historical documentation. The genus Equus evolved in North America, and during the first major glaciations of the late Pliocene (2–3 million years ago), some species crossed to Eurasia. North American and South American Equus species became extinct about 10,000 years ago from causes that are not fully understood, probably due to a combination of overhunting by humans and environmental causes, such as climatic changes (e.g., Clutton-Brock 1996). However, horses persisted continuously on the Iberian Peninsula since the Pleistocene (1.8 million years ago) even during the Mesolithic, when the horse became extinct north of the Pyrenees (Gonzaga 2004). Gene flow between horse populations of Iberia and North Africa occurred at multiple times throughout history. Exchanges between these two regions were particularly fre- quent during the long period of occupation of the Peninsula by the Moors (AD 711–1492), who brought Barb horses from North Africa (e.g., Oom 1992). Horses only returned to the American continent (the New World) in 1493, with the navigator Christopher Columbus and during the subsequent Spanish colonization period (Bort 2004; Primo 2004). Those stallions and mares were bought in Seville’s province, mainly from the peasant stock bred in the islands and salt marshes of the Guadalquivir River (Bort 2004). Historical records report the presence of around 70 horses on the first colony of La Española (Dominican Republic and Haiti) by the year 1503. Subsequently, horses were brought into Panama (1514), Mexico (1524), Brazil (1531), Peru (1532), Argentina (1535), and Florida (1538) (Digard 1994). By 1553, there were some 10,000 free-roaming horses in the area of Queretaro (Mexico) that spread throughout North and South America (Clutton-Brock 1992). Analysis of the mitochondrial DNA (mtDNA) control region sequence diversity has been an important tool for understanding the origin and diversification of domestic horses. Studies by Jansen et al. (2002), Lister et al. (1998), and Vilà et al. (2001) all point to extensive variation within and among breeds, with little congruence of haplotype assignment to breed or geographic region. These studies suggest that the domestic horse arose from several distinct wild horse populations and distributed over a moderately extensive geographic region large enough to contain con- siderable preexisting haplotype diversity and that there was considerable mixing of these haplotypes after domestication. Here we compare the mtDNA control region variation in Iberian and New World horse breeds in order to under- stand their relationships and test the accuracy of historical documentation of New World horse origins. Journal of Heredity 2006:97(2):107–113 doi:10.1093/jhered/esj020 Advance Access publication February 17, 2006 ª The American Genetic Association. 2006. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org. 107 b y g u e st o n O cto b e r 1 0 , 2 0 1 0 jh e re d .o xfo rd jo u rn a ls.o rg D o w n lo a d e d fro m mailto:journals.permissions@oxfordjournals.org mailto:cmluis@fc.ul.pt http://jhered.oxfordjournals.org/ Materials and Methods DNA Samples We analyzed 90 samples, representing 3 Iberian, 4 North American, and 12 South American breeds (Table 1). When pedigree information was available, we selected unrelated individuals. DNA was extracted from (1) fresh whole-blood samples after a high-salt extraction procedure (Montgomery and Sise 1990), (2) frozen whole-blood samples using the QIAmp Mini Blood Kit (Quiagen Inc., Valencia, CA), (3) frozen blood lysates using the Puregene Genomic DNA Isolation Kit (Gentra Systems Inc., Minneapolis, MN), and (iv) hair roots using Chelex-100 (Walsh et al. 1991). DNA Sequencing The universal primers L15926 and H16498 (Kocher et al. 1989) were used to amplify 360- to 442-bp fragments be- tween sites 15411 and 15852 according to the horse reference sequence X79547 (Xu and Árnason 1994), including the Table 1. Number of samples sequenced in this study and gathered from GenBank and the respective main geographic location, breed, breed’s code, and GenBank accession numbers Number of samples Geographic location Breed Code This study GenBank Accession number Iberia Asturcon AST — 6 AY519872, AY519875–76, AY519879–81 Caballo de Corro CCO — 6 AY519884–86, AY519888, AY519890, AY519897–98 Cartujano CTJ — 6 AY519897–98, AY519900, AY519902, AY519904, AY519906 Garrano GR 3 3 AF516500–01, AY997193, AY246231, AY246233, AY246235 Lusitano LUS 6 — AF516502–05, AY997194–95 Losino LOS — 6 AY519924–25, AY519928, AY519930, AY519932, AF466009 Mallorquina MA — 2 AF466013–14 Marismeño MAR — 6 AY519934, AY519936, AY519938, AY519940, AY519942, AY519944 Menorquina ME — 2 AF466015–16 Potoka POT — 6 AY519958–60, AY519963, AY519967, AF4666012 Pura Raza Española PRE 6 — AY917165–66, AY917168, AF516509–11 Sorraia SOR — 2 AF447764–65 Barb BA — 6 AJ413658, AJ413661, AJ413664–66, AJ413668 North America Florida Cracker FC 3 — AY997150–51, AY997192 Kiger Mustang KM 6 — AF516489–90, AY997152–55 Spanish Mustang SM 4 — AY997178–81 Sulphur Mustang SUL 6 — AF516494–95, AY997187, AY997200–02 Mustang MU — 6 AJ413753, AJ413797, AJ413802, AJ413804, AJ413807, AJ413817 South America Argentine Criollo AC 1 5 AF465986–90, AY997128 Brazilian Criollo CR 6 — AF516496, AF516498, AY997145, AY997147, AY997149, AY997190 Campolina CMP 6 — AY997139–44 Chilean Criollo CC 4 — AY997131–34 Chilote CH 4 — AY997135–38 Mangalarga BM 5 — AF516506–08, AY997129–30 Mangalarga Marchador MM 4 — AY997156–59 Pantaneiro PN 6 — AY997160–64, AY997199 Paso Fino PF 6 — AF516491–93, AY997197–99 Peruvian Paso Fino PVP 5 1 AF465993, AY997169–73 Puerto Rican Paso Fino RP 4 — AY997174–77 Venezuelan Spanish VS 5 — AY997182–86 The accession numbers in bold are new ones generated by this study. Journal of Heredity 2006:97(2) 108 b y g u e st o n O cto b e r 1 0 , 2 0 1 0 jh e re d .o xfo rd jo u rn a ls.o rg D o w n lo a d e d fro m http://jhered.oxfordjournals.org/ tRNA pro and hyper variable region I of the mtDNA control region. The polymerase chain reaction (PCR) cycle sequencing reactions were performed on both strands, twice for each sample, using the CycleReader� Auto DNA Sequencing Kit (MBI Fermentas GmbH, St. Leon-Rot, Germany), with infra- red dye 800–labeled PCR primers used as sequencing primers and with the ABI� Prism BigDye� Terminator Cycle Sequencing Ready Reaction Kit (Perkin Elmer Inc., Boston, MA). Sequences were determined with a Li-Cor� 4200S Sequencer and an ABI 377 DNA Sequencer and were ana- lyzed, respectively, with Li-Cor Image Analysis� software and Sequencing Analysis Software� v3.4.1 with free Factura�. The sequences obtained in this study were deposited in GenBank database, and their accession numbers are shown in Table 1. We also included in this study mtDNA control region sequences available from GenBank for 14 other Iberian and New World horse breeds (see Table 1). The Barb horse sequences were included as part of the Iberian group due to the historical link between this breed and the Iberian breeds. Sequences were aligned using the CLUSTALW software (Thompson et al. 1994) and truncated to 288 bp, between positions 15483 and 15770, according to the horse reference sample X75947 (Xu and Árnason 1994), allowing the com- parison with published sequences. Data Analysis Nucleotide diversity and haplotype (gene) diversity were ob- tained with the DNASP 4.00.5 software (Rozas et al. 2003), while the mean number of pairwise differences (MNPD) was obtained using the ARLEQUIN 2000 software (Schneider et al. 2000). Median-joining network (Bandelt et al. 1999) was gener- ated using NETWORK 4.1.0.8 software (available at http:// www.fluxus-engineering.com). Results mtDNA Lineages in Iberian and New World Horse Breeds We sequenced 90 individuals and identified 26 haplotypes of which 10 were new, namely, Hap_36, Hap_37, Hap_39, Hap_42, Hap_43, Hap_44, Hap_45, Hap_47, Hap_49, and Hap_50 (accession numbers AY997128, AF516507, AY997138, AY997131, AF516503, AY997158, AY997159, AF516492, AY997176, and AY997177, respectively). These haplotypes belonged to one Iberian and seven South American breeds (Table 1, Figure 1). Our analysis was based on a sample set composed of 90 sequences from this study and 63 available from Gen- Bank. The 153 mtDNA control region sequences yielded 54 different haplotypes defined by 44 polymorphic sites: 43 transitions and 1 transversion. For each breed, we iden- tified from two to six haplotypes, differing from the reference sequence (GenBank X79547) by 1–11 sites within the 288 bp analyzed (the table with all this information is available from the authors on request). Fifteen haplotypes (27.8%) were detected more than once, and 39 (72.2%) were singletons: 21 (53.8%) from Iberia (corresponding to 10 breeds), 2 (5.1%) from North America (one breed), and 16 (41%) from South America (eight breeds). Potoka is the breed with the highest percentage of singletons (100%) followed by Puerto Rican Paso Fino and Argentine Criollo, with 75% and 67%, respectively. The 54 haplotypes (26 from the present study) could be assigned to five (D1, D2, D3, C2, and A4) out of the 17 major mtDNA lineages defined by Jansen et al. (2002). Cluster D1 is considered, by these authors, as representative of Iberian and North African breeds. We further analyzed our sequences, and according to the presence of specific point mutations, we defined a total of seven major haplogroups. Their names indicate the mu- tation position and nucleotide used as diagnostic of the hap- logroups. As these point mutations were also present in clusters defined by Jansen et al. (2002), we decided to incor- porate the corresponding letters of these clusters into the haplogroup names. The sequences were assigned to the haplo- groups, and results are presented in Table 2. Figure 1 shows a median-joining network relating the mtDNA sequences of the analyzed breeds and the hap- logroups defined here. Haplogroup D494C,496G,534T,603C,649G is composed of indi- viduals from all breeds (Iberia, 44%; North America, 60%; South America, 48%) except from Menorquina and Sorraia. Included in this haplogroup is the modal sequence Hap_1 (D1 from Jansen et al. 2002) seen in high frequency in the Iberian and New World horse breeds analyzed here and hav- ing the highest overall frequency in all the geographic regions (Iberia, 26%; North America, 44%; South America, 29%). Haplogroup A542C,666A was the second most common with higher frequency of sequences in our sample set (12.4%) being found in all geographic regions (Iberia, 10.6%; North America, 24%; South America, 9.7%). Haplogroup A542T,666A almost exclusively comprised Iberian breeds, the exception was the North American Sul- phur Mustang breed. Haplogroup C617C comprised only South American breeds, and C601C was predominantly rep- resented by breeds from that region. Diversity of Iberian and New World Breeds Results from MNPD, nucleotide diversity, and haplotype diversity showed a similar pattern in all breeds (Table 3). The Sulphur Mustang presented the lowest values and Mallorquina the highest for all diversity indices, with the ex- ception of haplotype diversity where several breeds had the maximum value. For all diversity indices, Iberian breeds showed higher diversity values followed by South American and North American breeds (Table 4). Discussion From the 12 Iberian breeds studied, we provide new infor- mation for three: Garrano, Lusitano, and Pura Raza Española. Among the Iberian breeds, Menorquina and Sorraia showed Luı́s et al. � Iberian Origins of New World Horse Breeds 109 b y g u e st o n O cto b e r 1 0 , 2 0 1 0 jh e re d .o xfo rd jo u rn a ls.o rg D o w n lo a d e d fro m http://www.fluxus-engineering.com http://www.fluxus-engineering.com http://jhered.oxfordjournals.org/ the lowest diversity values. Menorquina (from an island of Spain with the same name) was established as a breed in the early 1980s (Gallardo PP and Andres Cara DF, unpub- lished). Approximately 70 horses were selected based on phenotypic characteristics and, since 1994, have been bred in a closed system. At the time of this breed’s establishment, a bottleneck effect surely occurred; however, we cannot exclude the sample size as a cause for this low diversity value. For the Sorraia horse, the lower diversity found was in ac- cordance with previous studies using different genetic mark- ers, namely, blood groups and biochemical polymorphisms (Oom and Cothran 1994), mtDNA (Luı́s et al. 2002a), micro- satellites (Luı́s et al. 2002b), and major histocompatibility complex genes (Luı́s et al. 2005). This Portuguese horse breed was recovered in 1937 from 12 founders (five males and seven females), and only two maternal lineages are pres- ently represented in the living population (Luı́s et al. 2002a). Of the five North American breeds analyzed, the Florida Cracker, Spanish Mustang, and Sulphur Mustang were tested for the first time. The North American samples showed lower numbers of haplotypes and haplotype diversity com- pared to the Iberian and South American breeds. All the North American populations in this analysis represent horses derived from feral populations. The Kiger, Florida Cracker, Figure 1. Median-joining network relating the mitochondrial DNA D-loop sequences observed in Iberian and New World horse breeds. Black represents Iberian Peninsula individuals, dark gray represents North American individuals, and light gray represents South America individuals. Circle size is proportional to sequence frequency. Free-form shapes represent haplogroups defined by certain point mutations. D1, D2, D3, C2, and A4 are clusters previously defined by Jansen et al. (2002). See Table 2 for haplogroup characteristics. 110 Journal of Heredity 2006:97(2) b y g u e st o n O cto b e r 1 0 , 2 0 1 0 jh e re d .o xfo rd jo u rn a ls.o rg D o w n lo a d e d fro m http://jhered.oxfordjournals.org/ Sulphur Mustang, and Spanish Mustang groups have recently become represented by breed registries. The first three are from single, isolated populations in Oregon, Florida, and Utah, respectively. The Spanish Mustang breed was formed with horses that originated from feral or Native American stock from all over North America. All were selected based on a phenotype that was believed to represent Spanish an- cestry. The Mustang group also is a collection of horses with feral origins and presumed Spanish physical character- istics. It is likely that the Kiger, Florida Cracker, and Sulphur Mustang breeds experienced bottlenecks or a limited num- ber of founders, resulting in lower diversity. The Sulphur Mustang has the lowest diversity with only two haplotypes found among six individuals. The Spanish Mustang and Mustang groups have the highest diversity of the North American breeds, comparable to the higher values for the other groups, which reflects their more diverse origins. From the 12 South American breeds considered in our study, 10—Brazilian Criollo, Campolina, Chilean Criollo, Chilote, Mangalarga, Mangalarga Marchador, Pantaneiro, Paso Fino, Puerto Rican Paso Fino, and Venezuelan Spanish—are analyzed for the first time. The higher variability of the South American breeds compared with the North American ones may be explained by the founding of North American breeds with horses coming from Mexico and the Caribbean. The South American breeds also have been selected for a greater diversity of forms and uses when compared to the North American horses, and some have been crossed to other non-Iberian type horses (Hendricks 1995). In comparison with the New World breeds, the Iberian samples showed the highest values for the diversity param- eters analyzed (including the frequency of singletons). This finding supports the historical documentation that Iberia was the source of much of the original stock that was used to populate the New World with horses. Also Iberia experi- enced an active interchange of horses with other breeding countries, such as the Pontic-Caspian steppes, Gaul, Italy, Macedonia, and Greece (Gonzaga 2004), that might have in- creased the variability of the Iberian horses. Therefore, the diversity in this region would be expectedly higher. The low variation in the New World breeds may be an indication of founder effect or a bottleneck during their establishment, an hypothesis previously suggested by Mirol et al. (2002) in their work with Argentinean Criollo. The high diversity of the mtDNA control region within the studied horse breeds confirms a differentiated ancestry, previously indicated by several authors (e.g., Hill et al. 2002; Jansen et al. 2002; Keyser-Tracqui et al. 2005; Kim et al. 1999; Lister et al. 1998; Lopes et al. 2005; Mirol et al. 2002; Vilà et al. 2001). However, some haplotypes have been identified as corresponding to specific breeds/geographic areas, namely, D1, first identified by Jansen et al. (2002), and further em- phasized by Lopes et al. (2005), as being well represented in Iberian breeds. Haplotype Hap_1, from our work, corre- sponds to D1 and was found in high frequency not only in the Iberian breeds but also in the New World ones. Besides Hap_1, the high frequency of Iberian and New World sam- ples belonging to haplogroup D494C,496G,534T,603C,649G (48%) is striking. This haplogroup has been considered represen- tative of the ancestral Iberian horse population (Royo et al. 2005). These two findings support the documented role of the Iberian breeds in the origin of New World horse populations. The second haplogroup with more representatives of Iberian and New World horse breeds is A542C,666A. This hap- logroup includes Marismeño horses (stripped horses from Table 2. Characterization of the haplogroups defined in this study with indication of mutation points, diagnostic nucleotide, and percentage of total samples from each geographic region assigned to each haplogroup Percentage of total samples in each haplogroup (%) Jansen et al. (2002) lineagesHaplogroup name Mutation points Diagnostic nucleotide Iberia South America North America A542T,666A 15542 T 12 — 8 A1 and A2 15666 A A542C,666A 15542 C 11 10 24 A3 15666 A B538G,709T 15538 G 12 3 — B1 and B2 15709 T C601C 15601 C 1.5 15 — C2 C617C 15617 C — 5 — C1 D494C,496G,534T,603C,649G 15494 C 44 48 60 D1, D2, and D3 15496 G 15534 T 15603 C 15649 G F740G 15740 G 1.5 3 — F2 Others a — — 18 16 8 A4 We also indicate lineages defined by Jansen et al. (2002) that were screened (bold) and lineages that despite not being found in this sample set would belong to our defined haplogroups because they have the diagnostic point mutations. a Haplotypes that are not assigned to the defined major haplogroups. 111 Luı́s et al. � Iberian Origins of New World Horse Breeds b y g u e st o n O cto b e r 1 0 , 2 0 1 0 jh e re d .o xfo rd jo u rn a ls.o rg D o w n lo a d e d fro m http://jhered.oxfordjournals.org/ the Guadalquivir salt marshes) that, like the Sorraia, are con- sidered a primitive Iberian equine type (Andrade 1954; Bort 2004) and therefore might have been extensively used for breeding in Iberia. The high frequency of New World horses in this haplogroup may be explained by historical records stat- ing that mares taken to the American continent by Christopher Columbus and during the subsequent Spanish colonization period were bought mainly from the stock bred in the islands and salt marshes of the Guadalquivir River (Bort 2004). Of the three geographic regions studied, South America is the only one having sequences that belong to haplogroup C617C, and it is also the region having almost the exclusive representation in haplogroup C601C. Indeed, the only non– South American samples that belong to this latter haplogroup are two individuals from the Caballo de Corro breed, a Celtic origin pony from Asturias. These two haplogroups named ‘‘C’’ share some mutation points with cluster C1 from Jansen et al. (2002), who consider this as distinctive for northern European ponies, known to have Celtic origin. These findings may indicate common matrilineal ancestors between Celtic ponies and South American breeds, a result that is in accor- dance with historical records because in 1508 the Spanish crown authorized the transport of 40 Celtic type horses (small and resistant) in the expedition organized by Alonso Ojeda and Diego Nicuesa to Panama (Mirol et al. 2002). The sharing of haplotypes between Iberia and New World, and especially of those belonging to the haplogroup considered as representative of the ancestral Iberian horse Table 3. Diversity indices in the analyzed breeds Geographic location Breed n nh MNPD SE Nucl. diver. SE Hd SE Iberia Asturcon 6 4 6.67 3.67 0.023 0.015 0.800 0.172 Caballo de Corro 6 3 3.80 2.22 0.013 0.009 0.733 0.155 Cartujano 6 4 7.73 4.20 0.027 0.017 0.800 0.172 Garrano 6 4 6.27 3.47 0.022 0.014 0.867 0.129 Lusitano 6 6 7.80 4.24 0.027 0.017 1.000 0.096 Losino 6 4 3.93 2.29 0.014 0.009 0.800 0.172 Mallorquina 2 2 9.00 6.71 0.031 0.033 1.000 0.500 Marismeño 6 4 6.20 3.43 0.021 0.014 0.867 0.129 Menorquina 2 2 3.00 2.45 0.010 0.012 1.000 0.500 Potoka 6 6 7.00 3.83 0.024 0.015 1.000 0.096 Pura Raza Española 6 5 5.67 3.16 0.020 0.013 0.933 0.122 Sorraia 2 2 3.00 2.45 0.104 0.012 1.000 0.500 Barb 6 5 6.53 3.60 0.023 0.014 0.933 0.122 South America Argentine Criollo 6 6 7.33 4.00 0.026 0.016 1.000 0.096 Brazilian Criollo 6 4 3.20 1.92 0.011 0.008 0.867 0.129 Campolina 6 4 4.33 2.49 0.015 0.010 0.867 0.129 Chilean Criollo 4 4 5.50 3.34 0.019 0.014 1.000 0.177 Chilote 4 3 5.50 3.34 0.019 0.014 0.833 0.222 Mangalarga 5 5 6.60 3.76 0.023 0.015 1.000 0.126 Mangalarga Marchador 4 4 5.50 3.34 0.019 0.014 1.000 0.177 Pantaneiro 6 5 5.40 3.03 0.019 0.012 0.933 0.122 Paso Fino 6 3 5.33 3.00 0.019 0.012 0.600 0.215 Peruvian Paso Fino 6 3 4.40 2.53 0.015 0.010 0.600 0.215 Puerto Rican Paso Fino 4 4 5.83 3.53 0.020 0.015 1.000 0.177 Venezuelan Spanish 5 3 5.20 3.03 0.018 0.012 0.700 0.218 North America Florida Cracker 3 2 5.33 3.53 0.019 0.015 0.667 0.314 Kiger Mustang 6 3 3.27 1.95 0.011 0.008 0.733 0.155 Spanish Mustang 4 3 7.00 4.17 0.024 0.017 0.833 0.222 Sulphur Mustang 6 2 0.33 0.38 0.001 0.002 0.333 0.215 Mustang 6 5 6.47 3.57 0.023 0.015 0.933 0.122 n, number of individuals; nh, number of haplotypes found; MNPD, mean number of pairwise differences; Nucl. diver., nucleotide diversity; Hd, haplotype (gene) diversity. Table 4. Diversity indices in the analyzed geographic regions Geographic location Total nh MNPD SE Nucl. diver. SE Hd SE Iberia 66 34 6.67 3.19 0.023 0.012 0.924 0.025 South America 62 27 5.52 2.69 0.019 0.010 0.898 0.030 North America 25 10 5.00 2.52 0.018 0.010 0.793 0.075 Total, number of individuals; nh, number of haplotypes found; MNPD, mean number of pairwise differences; Nucl. diver., nucleotide diversity; Hd, haplotype (gene) diversity. 112 Journal of Heredity 2006:97(2) b y g u e st o n O cto b e r 1 0 , 2 0 1 0 jh e re d .o xfo rd jo u rn a ls.o rg D o w n lo a d e d fro m http://jhered.oxfordjournals.org/ population (D494C,496G,534T,603C,649G), supports the widely accepted view of Iberian ancestry in American livestock (e.g., Miretti et al. 2004; Primo 2004). Although extensive migrations in the past make it difficult to find clear connections between mtDNA haplotypes and geographic groups, we present a set of genetic data revealing that New World breeds have a high frequency of haplotypes of Iberian origin and represent a subset of the diversity found in Iberia. Therefore, this study supports the historically docu- mented Iberian origins of New World horses. Acknowledgments To Lyn Ennis, Pam Henney, Dr. Rytis Juras, and Dr. Kathryn Graves, at the Equine Parentage Verification Laboratory, for laboratory help and sug- gestions. C.L. was supported by a PhD grant (SFRH/BD/3318/2000) from the Portuguese Foundation for Science and Technology (FCT/MCT), and C.B.-S. was supported by a postdoctoral grant (SFRH/BPD/116/2002) from the Portuguese Foundation for Science and Technology (FCT/MCT). The authors thank an anonymous referee for very constructive comments. References Andrade R, 1954. Alredor del Caballo Español. Lisboa: Colección de Estudios. 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Walsh PS, Metzger DA, and Higuchi R, 1991. Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. Biotechniques 10:506–513. Xu X and Árnason U, 1994. The complete mitochondrial DNA sequence of the horse, Equus caballus: extensive heteroplasmy of the control region. Gene 148:357–362. Received June 23, 2005 Accepted December 21, 2005 Corresponding Editor: Ernest Bailey 113 Luı́s et al. � Iberian Origins of New World Horse Breeds b y g u e st o n O cto b e r 1 0 , 2 0 1 0 jh e re d .o xfo rd jo u rn a ls.o rg D o w n lo a d e d fro m http://jhered.oxfordjournals.org/ work_cx5geaanurh47gt6gqz64fkqba ---- AGRICULTURAL Journal Of Agricultural Science And Agriculture ISSN : 2597-8713 Available on http://agris c cientific -work.org/inde x.php/agris c This is Under CC BY SA Media Influence of Planting And Concentration of Organic Liquid Fertilizer on The Growth And Results Lettuce (Lactucasatival.) Sri Purwanti, Bambang Gunawan, Ari Yulianto Page | r) Media Influence of Planting And Concentration of Organic Liquid Fertilizer on The Growth And Results Lettuce (Lactucasatival.) Sri Purwanti, Bambang Gunawan, Ari Yulianto Faculty of Agriculture, Merdeka University Surabaya Email: purwantialea@gmail.com ABSTRACT The lettuce is a leafy vegetable that comes from the (state) temperate. Historically, this plant has been cultivated since 2500 years ago. Lettuce plants came from the Americas. This is evidenced by Christopher Columbus in 1493 that found the plant lettuce in the western Hemisphere and the Bahamas (Rukmana, 1994). This study aims to determine the effect of growing media on growth factors, the influence of the concentration of liquid organic fertilizer (POC), the interaction effect of these two factors and yield of lettuce. The results showed There is a very real effect of growing media composition in all parameters studied were long observation of plants, number of leaves and fresh weight per plant. The best results were achieved by treatment K2 is 2 kg of manure per plant. There is a very real effect of concentrated liquid fertilizer (POC) "Supermer" on all parameters studied were long observation of plants, number of leaves and fresh weight per plant. The best results are achieved by P4 treatment The concentration POC 2 ml / liter of water. There is no real interaction due to a combination treatment of the media composition and concentration of liquid organic fertilizer (POC) "Supermes". Keywords: Growing Media, Concentration Liquid Organic Fertilizer and GrowthCrop 1. INTRODUCTION Lettuce is the leaf vegetables from the region (country) temperate. Historically, this plant has been cultivated since 2500 years ago. Lettuce plants came from the Americas. This is evidenced by Christopher Columbus in 1493 that found the plant lettuce in the western Hemisphere and the Bahamas (Rukmana, 1994). Lettuce is a vegetable species favored by the people of Indonesia. Customers ranging from lower-class society to the upper-class society. Lettuce is often eaten raw as a salad side dish delicious meal accompanied by sambal. Foreign cuisine such assaladusing lettuce to the mix, as well ashamburgers,hotdogs,and several other types of cuisine. This shows that the social aspect of Indonesian people easily accept the presence of lettuce for daily consumption (Haryantoetal.,1995). AGRICULTURAL Journal Of Agricultural Science And Agriculture ISSN : 2597-8713 Available on http://agris c cientific -work.org/inde x.php/agris c This is Under CC BY SA Media Influence of Planting And Concentration of Organic Liquid Fertilizer on The Growth And Results Lettuce (Lactucasatival.) Sri Purwanti, Bambang Gunawan, Ari Yulianto Page | r) In 2000, the Singapore government wants to develop vegetable crops in Riau, one of which is the lettuce. Vegetable production in Riau Province is still relatively low. The low production of leafy vegetables particularly apparent width of production in 2005, reaching 2,516 tons with an area of 365 ha of arable land are scattered throughout the district (Central Statistics Agency of Riau Province, 2006). The low productivity of lettuce plants is affected by many factors. One important factor that can affect the growth and production of a plant is the availability of nutrients. Can be improved nutrient availability in the soil to improve soil conditions through fertilization. In the ground is already available in natural foods, but not all of the land provide enough food for the plant. Land that does not provide the food needs to be assisted to increase the levels of the food in the ground, by giving fertilizer. One type of fertilizer given is an organic fertilizer that serves to provide organic nutrients for plants, improve soil structure and water retention in the soil. Organic fertilizers have an important function to loosen the surface soil layer, increasing the population of microorganisms, enhance absorption and store water, all of which can increase soil fertility as well (Sunardjono, 2005). Manure as well as organic fertilizer derived from domesticated animals include cow manure, dung water buffalo, goat manure, chicken manure and others. Cow dung is the type most dominant manure is used, because in addition to high haranya content is also readily available, it is caused by a number of cattle keepers so that the chairs can be used as fertilizer. Manure has many advantages over synthetic fertilizers. Besides Nitrogen (N), phosphorus (P) and Potassium (K) is quite high, manure contains enough nutrients complete. Given the importance of organic fertilizers mentioned above, it is necessary to do research on the growing media composition and the use of other organic fertilizers on growth and yield of lettuce plants. 2. METHODS This study used a randomized block design (RAK), where treatment using two factors: the first factor and the second factor media composition concentration of liquid organic fertilizer (POC) "Supermes". Each treatment was repeated 3 with two plant samples. AGRICULTURAL Journal Of Agricultural Science And Agriculture ISSN : 2597-8713 Available on http://agris c cientific -work.org/inde x.php/agris c This is Under CC BY SA Media Influence of Planting And Concentration of Organic Liquid Fertilizer on The Growth And Results Lettuce (Lactucasatival.) Sri Purwanti, Bambang Gunawan, Ari Yulianto Page | r) Analysis of the data used to determine the effect of treatment on the experimental analysis of variance F table is 5%. As for knowing which treatment is different then used to test the Least Significant Difference (LSD) with a level of 5% (Yitnosumarto, 1991). 3. RESULTS AND DISCUSSION 3.1. Plant Long Long Statistical analysis showed that the plant no significant interactions between the planting medium with a concentration factor of liquid organic fertilizer to the variable length of lettuce plants. Separately treatment plant media provides highly significant effect (F count> F1%> F5%) to the length of the plant at the age of observations 14, 21, 28 and 35 days after transplanting, whereas treatment concentration of liquid organic fertilizer significant effect (F1%> Fhitung > F5%) of the variable length crop at age 14, a significant influence (Fhitung> F1%> F5%) in the observation aged 21, 28 and 35 days after transplanting. Average length of lettuce plants at the media's treatment plant and the concentration of liquid organic fertilizer at various ages observations can be seen in Table 1 below. Table 1. Average length of Lettuce Plants In Treatment Media Concentration Plant and Fertilizer in Different AgeObservation Treatment Age Observation(HST) 14 21 28 35 K1 K2 6.13 a 6.75 b 9.08 a 11.08 b 15 , 42 a 16.25 b 21.79 a 24.67 b BNT 5% 0,37 0,79 0,54 0,94 P1 P2 P3 P4 6,00a 6.25 ab 6.58 b 6.92 b 9.00 a 9.50 ab 10.25 b 11.58 c 14.58 a 15.25 a 16.17 b 17.33 c 20.25 a 22.67 b 24.25 c 25.75 d BNT 5 % 0.52 1.12 0.77 1.33 Remarks: the figures are accompanied by the same letter are not significantly different shows on LSD 5% In table 1 above shows that in some of the observations seen growing media factor K2 treatment gives better value than K1. At the end of the observation value 24.67 cm K2 and K1 are significantly different with 21.79 cm. While liquid organic fertilizer concentration factor at the end of the treatment observation P4 provide better value is 25.75 cm and significantly different from the P3 (24.25 cm), P2 (22.67 cm) and P1 (20.25 cm). AGRICULTURAL Journal Of Agricultural Science And Agriculture ISSN : 2597-8713 Available on http://agris c cientific -work.org/inde x.php/agris c This is Under CC BY SA Media Influence of Planting And Concentration of Organic Liquid Fertilizer on The Growth And Results Lettuce (Lactucasatival.) Sri Purwanti, Bambang Gunawan, Ari Yulianto Page | r) Sri opinion Setyadi accordance Harjadi (2002), extension of the cells occurs due to the enlargement of new cells. This is supported by the presence of certain hormones that existed at the plant itself and the water content in the soil is also the sugar. This enables the cell walls stretch. Cell enlargement area directly behind the growing point. If the cells in this area is enlarged vacuole-vacuoles absorb relatively large amounts of water. As a result of the absorption of water and the presence of cell extenders hormone, it will be elongated cells, the cell walls grow thicker and stacked cellulose made from sugar so that it causes the cells to multiply and length. Manure contains macro and micro nutrients. Solid manure (macro) a lot of phosphorus, nitrogen and potassium (Mahrus, Bambang Wicaksono, Nurlina, Cholil, & Sri Wiwoho, 2017). Micro-nutrients contained in the manure such as calcium, magnesium, sulfur, sodium, iron, copper, and molybdenum. The above nutrients very useful to improve plant growth and development. Manure and other organic fertilizers may serve to increase soil organic matter content, providing micro-nutrients and improve soil structure. The use of these materials can also enhance microbial growth and turnover of nutrients in the soil. Other organic matter that can cause the nutrients they contain and increase the availability of other nutrients in the soil. Organic matter can save N fertilizer, but can also reduce the use of fertilizer P and K as well as increase crop production (Anonymous, 2010). 3.2. Number of leaves Statistical analysis showed that the number of leaves was no significant interaction between the factors of planting medium with a concentration of liquid organic fertilizer to variable number of leaves of lettuce plants. Separately treatment plant media give real effect (F1%> of F> F5%) of the number of leaves of the plant at the age of observation of 14 and 21 days after transplanting, the effect is highly significant (F count> F1%> F5%) to variable number of leaves of the plant on age 28 and 35 days after transplanting, whereas treatment concentration liquid organic fertilizers do not provide significant effect (F count of F> F5%) at the age of observation of 21 days after transplanting and highly significant effect (F count> F1%> F5%) in the observation age 28, 35 days after transplanting. AGRICULTURAL Journal Of Agricultural Science And Agriculture ISSN : 2597-8713 Available on http://agris c cientific -work.org/inde x.php/agris c This is Under CC BY SA Media Influence of Planting And Concentration of Organic Liquid Fertilizer on The Growth And Results Lettuce (Lactucasatival.) Sri Purwanti, Bambang Gunawan, Ari Yulianto Page | r) The average number of leaf lettuce plants on the media's treatment plant and the concentration of organic liquid fertilizer at various ages observations can be seen in table 2 below. Table 2. Average Number of Plants Leaf Lettuce On Media Treatment Plant and Fertilizer Concentration in Various AgeObservation Treatment Age Observation(HST) 14 21 28 35 K1 K2 3.83 a 4.13 b 5.83 a 6.25 b 7.92 a 8.29 b 10.67 a 11.96 b BNT 5% 0,28 0,31 0,26 0,49 P1 P2 P3 P4 3,75a ab3.92 4.08b 4.17b 5.58 a ab5.92 6.17 b 6.50 b 7.75 a 8.00 ab 8.17 b 8.50 b 10.50 a 11.08 ab 11.58 b 12.08 b BNT 5% 0.40 0.44 0.36 0.69 Remarks: the figures are accompanied by the same letter are not significantly different shows on LSD 5% in table 2 above shows that in some of the observations seen growing media factor K2 treatment provide better value than K1. At the end of the observation K2 provides significantly different value of 11.96 and with K1 is 10.67. While liquid organic fertilizer concentration factor at the end of the treatment observation P4 provide better value is 12.08 and not significantly different from P3 (11.58) and P2 (11,08) but significantly different from the P1, which is 10.50. Vegetative growth phase include the growth of roots, stems and leaves. In this phase of photosynthesis plants require a form of carbohydrates which will then be converted into energy for plant growth and development (Ali, 2015). At first, the carbohydrate derived from the endosperm storage network, when growth begins from the next carbohydrate germination will be formed from the process of photosynthesis after the plants have leaves. The process of photosynthesis allows the rapid increase in size as the number of leaves (Ashari, 1995). According Kusumo (1984) in Darliah et. al. (1994) that plant growth is the result of the growth and development of cells that depend on the supply of food, whether provided through the leaves and is absorbed by the roots out of the ground for the process of metabolism and protein synthesis. Meanwhile, according Sitompul and Guritno (1995) stated that an increase of the cells causing the cell walls grow thicker. In such a situation we AGRICULTURAL Journal Of Agricultural Science And Agriculture ISSN : 2597-8713 Available on http://agris c cientific -work.org/inde x.php/agris c This is Under CC BY SA Media Influence of Planting And Concentration of Organic Liquid Fertilizer on The Growth And Results Lettuce (Lactucasatival.) Sri Purwanti, Bambang Gunawan, Ari Yulianto Page | r) need a sufficient amount of carbohydrates, because with enough carbohydrates will produce enough energy to accelerate plant cell enlargement, which in this case is expressed in the form of long plant. Liquid organic fertilizer is a fertilizer that has a high effectiveness which can speed up or improve the growth, flowering and fruiting. Many contain liquid organic fertilizer NPK which is the main nutrient for plant growth and development are indispensable for the growth of vegetative parts of plants such as leaves, stems and roots (Sutejo, 1992). 3.3. Wet Weight Per Plant Statistical analysis of wet weight per plant showed that no significant interaction between the factors of planting medium with a concentration of liquid organic fertilizer to variable number of leaves of lettuce plants. Separately treatment plant media provides highly significant effect (F count> F1%> F5%) of the fresh weight per plant at the end of treatment, while treatment concentration of liquid organic fertilizer did not give a significant influence (Fhitung