id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_uovhjjurzffa5ony2uh7t6f63i	José M. Mato	Systems biology for hepatologists	2014	8	.pdf	application/pdf	5781	420	50	These methods, collectively known as omics, permit the determination of thousands of molecules (variations within genes, RNAs, proteins, metabolites) within a Abbreviations: DCA, deoxycholic acid; DMRs, differentially methylated regions; ENCODE, Encyclopedia of DNA Elements; FA, fatty acids; GC, gas chromatography; GWAS, genome-wide association study; HCC, hepatocellular carcinoma; MAT1A, methionine adenosyltransferase 1A; MS, mass spectrometry; NAFLD, nonalcoholic fatty liver disease; NASH, nonalcoholic steatohepatitis; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PHB1, prohibtin-1; SAMe, S-adenosylmethionine; SNP, single nucleotide polymorphism; TG, triglycerides; TMAO, trimethylamine N-oxide; UPLC, ultraperformance liquid chromatography. single nucleotide polymorphism (SNP) that is consistently associated with nonalcoholic fatty liver disease was associated with NAFLD progression to nonalcoholic steatohepatitis (NASH), alcoholic fatty liver disease, and hepatocellular carcinoma (HCC).6-8 The the genome that have key functions in the development of complex diseases, such as those of the liver. gene expression that is generally associated with transcriptional repression.11,12 Large-scale DNA methylation mapping studies have provided important insights	./cache/work_uovhjjurzffa5ony2uh7t6f63i.pdf	./txt/work_uovhjjurzffa5ony2uh7t6f63i.txt