id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_67xbevsuz5c7nkjae4iscm2koi	Dar-In Tai	A global perspective on hepatitis B-related single nucleotide polymorphisms and evolution during human migration	2017	9	.pdf	application/pdf	7933	3417	90	Genome-wide association studies have indicated that human leukocyte antigen (HLA)-DP and HLA-DQ play roles in persistent hepatitis B virus (HBV) infection in Asia. (SNPs) and to correlate these SNPs with chronic HBV infection among different populations, we conducted a global perspective response, which could have been a survival strategy during human migration to East Asia. The prevalence of chronic HBV infection in Africa is as high as in Asia; however, the HBV-related SNP genotypes are not present in Africa, and so the genetic mechanism of chronic HBV infection in Africa needs further exploration. human leukocyte antigen; IFNL4, interferon lambda 4; LWK, Luhya in Webuye, Kenya; NPC, nasopharyngeal carcinoma; SNP, single nucleotide genotypes of five immune-related SNPs differed significantly between Esan in Nigeria in Africa and of HBVand HLA-related SNPs show marked differences between South and East Asian genome samples high prevalence of chronic HBV infection in East Asia	./cache/work_67xbevsuz5c7nkjae4iscm2koi.pdf	./txt/work_67xbevsuz5c7nkjae4iscm2koi.txt