id author title date pages extension mime words sentences flesch summary cache txt work_62t35gyfb5fvxk3hilepuwrw4q Hans Oberleithner Endothelial cells as vascular salt sensors 2010 5 .pdf application/pdf 5406 1884 77 Endothelial cells as vascular salt sensors Endothelial cells as vascular salt sensors sodium gelates the shell of the endothelial cell, whereas the KEYWORDS: aldosterone; amiloride; atomic force microscopy; cell stiffness; SODIUM: 'STIFFENER' OF VASCULAR ENDOTHELIAL CELLS in sodium concentration on endothelial function has been POTASSIUM: SOFTENER OF VASCULAR ENDOTHELIAL CELLS potassium on endothelial cells (Figure 3). in endothelial cell stiffness can be induced by raising the between stiffness and eNOS activity, (2) extracellular sodium influences eNOS activity and stiffness only at low sodium Vascular endothelial cells undergo large changes in shape Change in endothelial cell stiffness (%) sodium-induced increase in cell stiffness. potassium concentrations, an increase can, paradoxically, hyperpolarize the membrane potential of endothelial cells.27 Such a endothelial cell leading to increased eNOS activity. Figure 5 | Hypothesis for how sodium and potassium control vascular endothelial cells. Sodium: 'stiffener' of Vascular Endothelial Cells ���������������������������������������������������������������������������������������������������������������������������������������������������������������������� Potassium: Softener of Vascular Endothelial Cells ���������������������������������������������������������������������������������������������������������������������������������������������������������������������� ./cache/work_62t35gyfb5fvxk3hilepuwrw4q.pdf ./txt/work_62t35gyfb5fvxk3hilepuwrw4q.txt