id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
10_1101-2021_01_06_425657	Johnson, Zane	The SCF<sup>Met30</sup> ubiquitin ligase senses cellular redox state to regulate the transcription of sulfur metabolism gene	2021	35	.pdf	application/pdf	14821	2231	75	The SCFMet30 ubiquitin ligase senses cellular redox state to regulate the transcription of sulfur metabolism gene In yeast, control of sulfur amino acid metabolism relies upon Met4, a transcription factor which 15 When yeast cells sense sufficiently high levels of sulfur in the environment, the MET gene 40 work together to regulate levels of MET gene transcripts in response to the availability of sulfur or 51 acute depletion of sulfur metabolites and the activation of the MET gene regulon (Sutter et al., 88 sulfur metabolic pathway was sufficient to rescue Met30 E3 ligase activity and re-ubiquitinate 125 yeast cells starved of sulfur readily reversed Met30 cysteine oxidation. Since the cysteine residues within Met30 became rapidly oxidized in sulfur-free conditions, the 214 we performed in parallel the Met30-Flag IP with cells grown in both high and low sulfur 223 metabolite levels in yeast, Met30, is regulated by reversible cysteine oxidation.	./cache/10_1101-2021_01_06_425657.pdf	./txt/10_1101-2021_01_06_425657.txt