id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
10_1101-2021_01_05_425440	Rossetti, Cecilia	Thermal proteome profiling reveals distinct target selectivity for differentially oxidized oxysterols	2021	12	.pdf	application/pdf	5468	401	56	Thermal proteome profiling reveals distinct target selectivity for differentially oxidized oxysterols systematic identification of oxysterol target proteins using thermal proteome profiling (TPP). two proteins identified as targets for more than one oxysterol. Identification of oxysterol target proteins using thermal proteome profiling To identify potential oxysterol target proteins, TPP was selected as the method of choice [11][12] Target identification of oxysterols using thermal proteome profiling. profiling experiments and criteria for the identification of putative oxysterol targets; B) Structures of the tested proteins, upon the incubation of HeLa cell lysates with the different oxysterols (Figure 1C). validates the use of TPP for identifying novel oxysterol target proteins, but also highlights the polymerase III transcription complex was identified as putative oxysterol targets (Figure 2C). We focused our initial analysis of specific oxysterol target proteins with 7-KC, as it is the most approach for oxysterol target protein identification. profiles, with only two proteins identified as targets of more than one oxysterol.	./cache/10_1101-2021_01_05_425440.pdf	./txt/10_1101-2021_01_05_425440.txt