id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
10_1101-2021_01_04_425348	Hirayama, Chihiro	Distinct roles and actions of PDI family enzymes in catalysis of nascent-chain disulfide formation	2021	49	.pdf	application/pdf	15285	2586	78	ERp46-catalyzed disulfide bond formation in ribosome-associated nascent chains 35 and PDI could introduce a disulfide bond into the ribosome-associated HSA nascent 103 In contrast to PDI, ERp46 could introduce a native disulfide bond into RNC 181 Like PDI, ERp46 also introduced a non-native disulfide bond 182 Accessibility of PDI/ERp46 to cysteines on the ribosome-HSA nascent chain 195 Disulfide bond introduction into a longer HSA nascent chain by PDI/ERp46 251 somehow prevent PDI and ERp46 from introducing a disulfide bond into RNC 95-aa. PDI and ERp46 are predicted to bind RNCs transiently during disulfide bond 315 PDI I289A and ERp57 were found to introduce a disulfide bond into RNC 82-aa at a 375 B, D PDI(B) and ERp46 (D)-mediated disulfide bond introduction into RNC 82-aa 776 Figure 4 Disulfide bond introduction into RNC 95-aa by PDI and ERp46 787 A Disulfide bond introduction into RNC 82-aa by PDI I289A (upper) and ERp57 838 	./cache/10_1101-2021_01_04_425348.pdf	./txt/10_1101-2021_01_04_425348.txt