id author title date pages extension mime words sentences flesch summary cache txt 10_1101-2020_12_31_424971 Gamper, Howard Insights into Genome Recoding from the Mechanism of a Classic +1-Frameshifting tRNA 2021 59 .pdf application/pdf 23040 1945 66 codons by a +1-frameshifting tRNA, SufB2, that contains an extra nucleotide in its anticodon loop. We show that SufB2 uses triplet anticodon-codon pairing in the 0-frame to initially decode the 33 loops (ASLs) of +1-frameshifting tRNAs have been found to use triplet anticodon-codon pairing 78 +1 frameshifting activity of SufB2 relative to its closest counterpart, ProL, at a CCC-C motif, and 103 SufB2 and ProL lacking all post-transcriptional modifications (termed the G37-state tRNAs), or 131 ribosome in response to the CCC-C motif, and that the efficiency of delivery by G37-state SufB2 202 SufB2 exhibits triplet pairing in the 0-frame at the A site (Figures 3a-c, Supplementary Table 2, 290 SufB2 anticodon loop and/or the CCC-C motif at the 2nd codon position of the mRNA. as a function of time for delivery of G37or native-state SufB2or ProL-TC to the A site of a 70S 1267 ./cache/10_1101-2020_12_31_424971.pdf ./txt/10_1101-2020_12_31_424971.txt