id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
10_1101-2020_05_10_087288	Liu, Lin	Heparan sulfate proteoglycans as attachment factor for SARS-CoV-2	2021	20	.pdf	application/pdf	7229	922	74	Surface plasma resonance (SPR) showed the SARS-CoV-2 spike protein binds SARS-CoV-2, coronavirus, heparan sulfate, heparin, spike glycoprotein, microarray, glycoprotein of the virus to angiotensin-converting enzyme 2 (ACE2) of the host.2 SARSCoV is closely related to SARS-CoV-2 and employs the same receptor.3 The spike protein RBD domain of SARS-CoV-2 spike protein can bind with heparin. binding of immobilized heparin with SARS-CoV-2 related proteins (A) RBD, (B) spike monomer, Intrigued by these results, we examined if the SARS-CoV-2 proteins bind to heparan Binding of synthetic heparan sulfate oligosaccharides to SARS-CoV-2-spike and RBD (A) Binding of SARS-CoV-2-spike (10 µg/mL) to the heparan sulfate microarray. immobilized ACE2 with SARS-CoV-2 derived proteins (A) RBD, (B) spike monomer, and (C) Binding of ACE2 antibody, SARS-CoV-2 RBD, and heparan sulfate antibody to of heparin to inhibit the binding between RBD or spike with ACE2. 8. Mycroft-West, C.; Su, D.; Elli, S.; Li, Y.; Guimond, S.; Miller, G.; Turnbull, J.; 	./cache/10_1101-2020_05_10_087288.pdf	./txt/10_1101-2020_05_10_087288.txt