id author title date pages extension mime words sentences flesch summary cache txt work_r3pghfglovc7bfij3ji2caiioy Munira A. Basrai Small Open Reading Frames: Beautiful Needles in the Haystack 1997 5 .pdf application/pdf 3381 340 63 (here abbreviated smORFs) probably encode very interesting proteins in all organisms, including humans. length; biological sequences also contain many ORFs >99 codons long that 100–150 codons include numerous artifactual ORFs (Fickett 1995; Das et al. total number of ORFs in the yeast genome of all lengths between 2 and 1000 which ORFs to annotate in the yeast genome. examined the probability of functionality of short ORFs and described computational techniques based on a combination of codon usage, amino acid composition, and dipeptide frequencies in the encoded protein to estimate the likelihood of gene function. There are also small ORFs encoding transporter proteins, homeobox by examining the set of proteins identified by amino acid sequencing of randomly selected two-dimensional gel smORFs to long ORFs to the entire yeast genome-www.stanford.edu/Saccharomyces/) and MIPS (http://speedy.mips.biochem.mpg.de/) to identify genes and by the genome sequencing efforts, SAGE also identified ∼160 small proteins will be identified by this ./cache/work_r3pghfglovc7bfij3ji2caiioy.pdf ./txt/work_r3pghfglovc7bfij3ji2caiioy.txt