[PDF] A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans | Semantic Scholar Skip to search formSkip to main content> Semantic Scholar's Logo Search Sign InCreate Free Account You are currently offline. Some features of the site may not work correctly. DOI:10.1210/jc.2017-01196 Corpus ID: 3789659A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans @article{McAninch2018ACD, title={A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans}, author={Elizabeth A McAninch and K. Rajan and D. Evans and Sungro Jo and L. Chaker and R. Peeters and D. Bennett and D. Mash and A. Bianco}, journal={The Journal of Clinical Endocrinology & Metabolism}, year={2018}, volume={103}, pages={1818–1826} } Elizabeth A McAninch, K. Rajan, +6 authors A. Bianco Published 2018 Medicine The Journal of Clinical Endocrinology & Metabolism Context A common single nucleotide polymorphism in DIO2, Thr92AlaD2, has been associated with a transcriptome typically found in neurodegenerative diseases in postmortem human brain tissue. Objective To determine whether Thr92AlaD2 is associated with incident Alzheimer disease (AD). Design Population-based study; human brain tissue microarray. Setting Community-based cohorts from Chicago and northeastern Illinois and religious clergymen from across the United States constituted the… Expand View on Wolters Kluwer academic.oup.com Save to Library Create Alert Cite Launch Research Feed Share This Paper 22 CitationsBackground Citations 5 View All Figures, Tables, and Topics from this paper figure 1 table 1 table 2 table 3 table 4 View All 5 Figures & Tables Alzheimer's Disease Neurodegenerative Disorders Confidence Intervals National Institute on Aging (U.S.) Manuscripts Amino Acids Cognition Disorders Lithium Diabetes Mellitus Inheritance Patterns DIO2 gene Autopsy Conflict (Psychology) Macrophage-Activating Factors hemoglobin North Chicago Doctor of Chiropractic Gastrointestinal system Biological Markers Stratification Data Table Paper Mentions News Article Thyroid Gene Variation May Increase Risk for Alzheimer’s Disease in African Americans Health Medicinet 14 March 2018 22 Citations Citation Type Citation Type All Types Cites Results Cites Methods Cites Background Has PDF Publication Type Author More Filters More Filters Filters Sort by Relevance Sort by Most Influenced Papers Sort by Citation Count Sort by Recency Brain MRI findings related to Alzheimer's disease in older African American adults. O. Carmichael, R. Newton Medicine Progress in molecular biology and translational science 2019 Save Alert Research Feed Low serum concentration of free triiodothyronine (FT3) is associated with increased risk of Alzheimer’s disease Patrick S. Quinlan, Alexandra Horvath, A. Wallin, J. Svensson Medicine Psychoneuroendocrinology 2019 9 Save Alert Research Feed Deiodinases, organic anion transporter polypeptide polymorphisms and ischemic stroke outcomes S. Taroza, D. Rastenytė, A. Podlipskytė, Vaiva Patamsytė, N. Mickuvienė Medicine Journal of the Neurological Sciences 2019 1 Save Alert Research Feed Type 2 Deiodinase Thr92Ala Polymorphism is Associated with a Reduction in Bone Mineral Density: A Community-based Korean Genome and Epidemiology Study. Y. E. Kang, Young Mi Kang, B. Park, M. Shong, Hyon-Seung Yi Medicine Clinical endocrinology 2020 Save Alert Research Feed Assessment of children in the autistic spectrum disorder that carry the Thr92Ala-DIO2 polymorphism A. A. E Marcondes, T. G. B. Gomez, +6 authors M. O. Ribeiro Medicine Journal of Endocrinological Investigation 2021 View 1 excerpt, cites background Save Alert Research Feed Pathophysiological relevance of deiodinase polymorphism A. Bianco, B. S. Kim Medicine Current opinion in endocrinology, diabetes, and obesity 2018 16 Save Alert Research Feed Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain Sungro Jo, Tatiana L. Fonseca, +19 authors A. Bianco Chemistry, Medicine The Journal of clinical investigation 2019 26 PDF View 3 excerpts, cites background Save Alert Research Feed Correction: Single Nucleotide Polymorphisms in Thyroid Hormone Transporter Genes MCT8, MCT10 and Deiodinase DIO2 Contribute to Inter-Individual Variance of Executive Functions and Personality Traits. J. Uter, U. Krämer, +6 authors T. Münte Biology, Medicine Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2020 PDF Save Alert Research Feed Identification of potential key genes and pathway linked with sporadic Creutzfeldt-Jakob disease based on integrated bioinformatics analyses B. Vastrad, C. Vastrad, I. Kotturshetti Medicine medRxiv 2020 PDF Save Alert Research Feed Thyroid hormone, gene expression, and Central Nervous System: Where we are. G. Giannocco, M. M. L. Kizys, R. Maciel, J. S. de Souza Biology, Medicine Seminars in cell & developmental biology 2020 Save Alert Research Feed ... 1 2 3 ... References SHOWING 1-10 OF 68 REFERENCES SORT BYRelevance Most Influenced Papers Recency Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. C. Reitz, G. Jun, +39 authors R. Mayeux Medicine JAMA 2013 280 PDF Save Alert Research Feed Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease J. Lambert, C. Ibrahim-Verbaas, +179 authors P. Amouyel Biology, Medicine Nature Genetics 2013 2,722 PDF Save Alert Research Feed A Meta-Analysis of Alzheimer's Disease Incidence and Prevalence Comparing African-Americans and Caucasians. K. Steenland, F. Goldstein, A. Levey, W. Wharton Medicine Journal of Alzheimer's disease : JAD 2016 76 PDF View 1 excerpt Save Alert Research Feed Genetic susceptibility for Alzheimer disease neuritic plaque pathology. J. Shulman, K. Chen, +14 authors D. Bennett Biology, Medicine JAMA neurology 2013 130 PDF View 3 excerpts Save Alert Research Feed Prevalent polymorphism in thyroid hormone-activating enzyme leaves a genetic fingerprint that underlies associated clinical syndromes. Elizabeth A McAninch, Sungro Jo, +12 authors A. Bianco Biology, Medicine The Journal of clinical endocrinology and metabolism 2015 54 PDF View 10 excerpts, references background and methods Save Alert Research Feed Mixed pathology is more likely in black than white decedents with Alzheimer dementia L. Barnes, S. Leurgans, +6 authors J. Schneider Medicine Neurology 2015 73 Save Alert Research Feed Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects. N. Grarup, M. K. Andersen, +7 authors O. Pedersen Biology, Medicine The Journal of clinical endocrinology and metabolism 2007 56 PDF View 3 excerpts, references background Save Alert Research Feed The Rush Memory and Aging Project: Study Design and Baseline Characteristics of the Study Cohort D. Bennett, J. Schneider, A. Buchman, C. F. Mendes de Leon, J. L. Bienias, R. Wilson Medicine Neuroepidemiology 2005 300 View 7 excerpts, references background and methods Save Alert Research Feed The association of polymorphisms in the type 1 and 2 deiodinase genes with circulating thyroid hormone parameters and atrophy of the medial temporal lobe. F. D. de Jong, R. Peeters, +5 authors M. Breteler Biology, Medicine The Journal of clinical endocrinology and metabolism 2007 93 PDF View 2 excerpts, references results and background Save Alert Research Feed Association analyses of variants in the DIO2 gene with early-onset type 2 diabetes mellitus in Pima Indians. S. Nair, Y. L. Muller, E. Ortega, S. Kobes, C. Bogardus, L. Baier Biology, Medicine Thyroid : official journal of the American Thyroid Association 2012 32 View 3 excerpts, references background Save Alert Research Feed ... 1 2 3 4 5 ... Related Papers Abstract Figures, Tables, and Topics Paper Mentions 22 Citations 68 References Related Papers Stay Connected With Semantic Scholar Sign Up About Semantic Scholar Semantic Scholar is a free, AI-powered research tool for scientific literature, based at the Allen Institute for AI. Learn More → Resources DatasetsSupp.aiAPIOpen Corpus Organization About UsResearchPublishing PartnersData Partners   FAQContact Proudly built by AI2 with the help of our Collaborators Terms of Service•Privacy Policy The Allen Institute for AI By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License ACCEPT & CONTINUE