[PDF] Mapping biochemistry to metabolism: FDG-PET and amyloid burden in Alzheimer's disease. | Semantic Scholar Skip to search formSkip to main content> Semantic Scholar's Logo Search Sign InCreate Free Account You are currently offline. Some features of the site may not work correctly. DOI:10.1097/00001756-199909290-00007 Corpus ID: 13910131Mapping biochemistry to metabolism: FDG-PET and amyloid burden in Alzheimer's disease. @article{Mega1999MappingBT, title={Mapping biochemistry to metabolism: FDG-PET and amyloid burden in Alzheimer's disease.}, author={M. Mega and T. Chu and J. Mazziotta and K. H. Trivedi and P. Thompson and A. Shah and G. Cole and S. Frautschy and A. Toga}, journal={Neuroreport}, year={1999}, volume={10 14}, pages={ 2911-7 } } M. Mega, T. Chu, +6 authors A. Toga Published 1999 Biology, Medicine Neuroreport We evaluated the relationship between amyloid-beta protein (A beta) concentration and the metabolic abnormality in an Alzheimer's disease (AD) patient as measured by [18F]fluorodeoxyglucose positron emission tomography (FDG-PET). Across most regions there were significant inverse correlations among FDG-PET intensity values and both insoluble. The temporal lobe samples showed no significant correlation between FDG-PET values and A beta deposition. Findings support A beta as contributing to the… Expand View on PubMed alzheimer.neurology.ucla.edu Save to Library Create Alert Cite Launch Research Feed Share This Paper 50 CitationsHighly Influential Citations 1 Background Citations 11 Methods Citations 3 View All Topics from this paper Fluorodeoxyglucose F18 Alzheimer's Disease Positron-Emission Tomography Temporal Lobe Positrons Brain Diseases, Metabolic Biochemistry Contribution 50 Citations Citation Type Citation Type All Types Cites Results Cites Methods Cites Background Has PDF Publication Type Author More Filters More Filters Filters Sort by Relevance Sort by Most Influenced Papers Sort by Citation Count Sort by Recency β-Amyloid is associated with aberrant metabolic connectivity in subjects with mild cognitive impairment F. Carbonell, Arnaud Charil, A. Zijdenbos, Alan C. Evans, B. 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