[PDF] A randomized controlled trial of prochlorperazine versus metoclopramide for treatment of acute migraine. | Semantic Scholar Skip to search formSkip to main content> Semantic Scholar's Logo Search Sign InCreate Free Account You are currently offline. Some features of the site may not work correctly. DOI:10.1016/J.ANNEMERGMED.2007.09.027 Corpus ID: 6407986A randomized controlled trial of prochlorperazine versus metoclopramide for treatment of acute migraine. @article{Friedman2008ARC, title={A randomized controlled trial of prochlorperazine versus metoclopramide for treatment of acute migraine.}, author={B. Friedman and D. Esses and C. Sol{\'o}rzano and N. Dua and P. Greenwald and Radu Rădulescu and E. Chang and Michael L. Hochberg and Caron Campbell and A. Aghera and Tyson Valentin and J. Paternoster and P. Bijur and R. Lipton and E. Gallagher}, journal={Annals of emergency medicine}, year={2008}, volume={52 4}, pages={ 399-406 } } B. Friedman, D. Esses, +12 authors E. Gallagher Published 2008 Medicine Annals of emergency medicine STUDY OBJECTIVE We compare prochlorperazine 10 mg intravenously versus metoclopramide 20 mg intravenously for the emergency department (ED) treatment of acute migraine. METHODS This was a randomized, double-blind, clinical trial comparing 2 parenteral dopamine antagonists. Both drugs were administered during 15 minutes with 25 mg intravenous diphenhydramine. Pain scores on a numeric rating scale were assessed at baseline, every 30 minutes for 2 hours, and by telephone 24 hours after discharge… Expand View on PubMed evidencebasedpractice.osumc.edu Save to Library Create Alert Cite Launch Research Feed Share This Paper 74 CitationsHighly Influential Citations 4 Background Citations 21 Methods Citations 3 Results Citations 2 View All Figures, Tables, and Topics from this paper figure 1 table 1 table 2 figure 2 figure 3 table 3 table 4 View All 7 Figures & Tables Prochlorperazine Metoclopramide Migraine Disorders Diphenhydramine Dopamine Headache Erectile dysfunction Pain Accident and Emergency department Confidence Intervals Numbers Addison Disease Alveolar rhabdomyosarcoma Paper Mentions Interventional Clinical Trial Intravenous Fluids in Benign Headaches Trail Migraine headache has a 1-year period prevalence in the US of 11.7% and accounts for approximately 1.2 million migraine visits to US emergency departments per year . There are… Expand Conditions Headache Intervention Drug University Medical Center of Southern Nevada May 2017 - May 2019 Interventional Clinical Trial A Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache This randomized, double-blind trial will compare the clinical efficacy of IV acetaminophen to that of IV ketorolac as adjuncts to standard therapy (prochlorperazine and diphenhydramine… Expand Conditions Headache Intervention Drug Lakeland Health September 2017 - September 2018 Blog Post Prochlorperazine, Metoclopramide, and Diphenhydramine for Acute Migraine Headache ALiEM 10 January 2018 Interventional Clinical Trial The CHECK Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine This study compares the efficacy of low dose Ketamine versus Compazine for the control of headache in patients presenting to the Emergency Department.   Conditions Headache Intervention Drug University Medical Center of Southern Nevada March 2016 - March 2017 74 Citations Citation Type Citation Type All Types Cites Results Cites Methods Cites Background Has PDF Publication Type Author More Filters More Filters Filters Sort by Relevance Sort by Most Influenced Papers Sort by Citation Count Sort by Recency Randomized trial of IV valproate vs metoclopramide vs ketorolac for acute migraine B. Friedman, L. Garber, +5 authors E. Gallagher Medicine Neurology 2014 30 Save Alert Research Feed Metoclopramide for acute migraine: a dose-finding randomized clinical trial. B. Friedman, L. Mulvey, +4 authors E. Gallagher Medicine Annals of emergency medicine 2011 48 Save Alert Research Feed A Randomized Controlled Trial of Intravenous Haloperidol vs. Intravenous Metoclopramide for Acute Migraine Therapy in the Emergency Department. Matthew E Gaffigan, David I. Bruner, Courtney Wason, Amy Pritchard, K. Frumkin Medicine The Journal of emergency medicine 2015 31 PDF Save Alert Research Feed Randomized study of IV prochlorperazine plus diphenhydramine vs IV hydromorphone for migraine B. Friedman, Eddie Irizarry, +6 authors E. Gallagher Medicine Neurology 2017 34 PDF View 1 excerpt, cites background Save Alert Research Feed Comparison of Intravenous Metoclopramide and Acetaminophen in Primary Headaches: a Randomized Controlled Trial G. Faridaalaee, S. Rahmani, +5 authors F. Rahmani Medicine Emergency 2015 7 PDF View 1 excerpt, cites background Save Alert Research Feed Olanzapine versus droperidol for the treatment of primary headache in the emergency department. C. Hill, J. Miner, M. Martel Medicine Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2008 27 Save Alert Research Feed Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study) K. Childress, Christina Dothager, J. Gavard, Sara Lebovitz, Catherine Laska, D. Mostello Medicine American journal of perinatology 2018 6 Save Alert Research Feed A Comparison of Headache Treatment in the Emergency Department: Prochlorperazine Versus Ketamine T. Zitek, M. Gates, +6 authors J. M. Clark Medicine Annals of emergency medicine 2018 17 PDF Save Alert Research Feed Diphenhydramine as Adjuvant Therapy for Acute Migraine: An Emergency Department-Based Randomized Clinical Trial. B. Friedman, Lisa Cabral, +4 authors E. Gallagher Medicine Annals of emergency medicine 2016 24 PDF Save Alert Research Feed Randomized Trial of Adding Parenteral Acetaminophen to Prochlorperazine and Diphenhydramine to Treat Headache in the Emergency Department Stefan Meyering, R. Stringer, Matthew Hysell Medicine The western journal of emergency medicine 2017 3 Save Alert Research Feed ... 1 2 3 4 5 ... References SHOWING 1-10 OF 35 REFERENCES SORT BYRelevance Most Influenced Papers Recency A trial of metoclopramide vs sumatriptan for the emergency department treatment of migraines B. Friedman, J. Corbo, +4 authors E. Gallagher Medicine Neurology 2005 90 View 2 excerpts, references methods and background Save Alert Research Feed Intravenous chlorpromazine vs intravenous metoclopramide in acute migraine headache. J. Cameron, P. Lane, M. Speechley Medicine Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 1995 80 View 1 excerpt, references methods Save Alert Research Feed Intramuscular prochlorperazine versus metoclopramide as single-agent therapy for the treatment of acute migraine headache. J. Jones, S. Pack, E. Chun Medicine The American journal of emergency medicine 1996 93 View 2 excerpts, references background Save Alert Research Feed Intravenous sodium valproate versus prochlorperazine for the emergency department treatment of acute migraine headaches: a prospective, randomized, double-blind trial. D. Tanen, S. Miller, T. French, R. Riffenburgh Medicine Annals of emergency medicine 2003 93 View 1 excerpt, references methods Save Alert Research Feed Randomized, placebo-controlled evaluation of prochlorperazine versus metoclopramide for emergency department treatment of migraine headache. M. Coppola, D. Yealy, R. Leibold Medicine Annals of emergency medicine 1995 212 Save Alert Research Feed Randomized double-blind trial of intravenous prochlorperazine for the treatment of acute headache. J. Jones, D. Sklar, J. Dougherty, W. White Medicine JAMA 1989 165 View 1 excerpt, references background Save Alert Research Feed Intravenous chlorpromazine in the emergency department treatment of migraines: a randomized controlled trial. M. Bigal, C. Bordini, J. Speciali Medicine The Journal of emergency medicine 2002 93 Save Alert Research Feed Acute migraine treatment with droperidol S. Silberstein, W. Young, J. E. Mendizabal, J. Rothrock, A. Alam Medicine Neurology 2003 95 View 1 excerpt, references background Save Alert Research Feed Droperidol vs. prochlorperazine for benign headaches in the emergency department. J. Miner, S. J. Fish, S. W. Smith, M. Biros Medicine Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2001 79 View 2 excerpts, references methods and background Save Alert Research Feed Intravenous chlorpromazine versus intramuscular sumatriptan for acute migraine. A. Kelly, M. Ardagh, C. Curry, J. D’Antonio, S. Zebic Medicine Journal of accident & emergency medicine 1997 51 PDF View 1 excerpt, references methods Save Alert Research Feed ... 1 2 3 4 ... Related Papers Abstract Figures, Tables, and Topics Paper Mentions 74 Citations 35 References Related Papers Stay Connected With Semantic Scholar Sign Up About Semantic Scholar Semantic Scholar is a free, AI-powered research tool for scientific literature, based at the Allen Institute for AI. 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