id	sid	tid	token	lemma	pos
work_dbbvwgi6and2fokqess5tojy2u	1	1	Microsoft	Microsoft	NNP
work_dbbvwgi6and2fokqess5tojy2u	1	2	Word	Word	NNP
work_dbbvwgi6and2fokqess5tojy2u	1	3	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	1	4	100710.docx	100710.docx	CD
work_dbbvwgi6and2fokqess5tojy2u	1	5	Oncotarget56083www.impactjournals.com/oncotarget	oncotarget56083www.impactjournals.com/oncotarget	NN
work_dbbvwgi6and2fokqess5tojy2u	1	6	www.impactjournals.com/oncotarget/	www.impactjournals.com/oncotarget/	NNP
work_dbbvwgi6and2fokqess5tojy2u	1	7	Oncotarget	Oncotarget	NNP
work_dbbvwgi6and2fokqess5tojy2u	1	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	1	9	Vol	Vol	NNP
work_dbbvwgi6and2fokqess5tojy2u	1	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	2	1	7	7	LS
work_dbbvwgi6and2fokqess5tojy2u	2	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	2	3	No	no	UH
work_dbbvwgi6and2fokqess5tojy2u	2	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	3	1	35	35	CD
work_dbbvwgi6and2fokqess5tojy2u	3	2	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	3	3	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	4	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	3	5	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	3	6	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	3	7	essential	essential	JJ
work_dbbvwgi6and2fokqess5tojy2u	3	8	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	3	9	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	3	10	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	3	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	3	12	regulates	regulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	3	13	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	3	14	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	3	15	Monica	Monica	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	16	Cubillos	Cubillos	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	17	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	3	18	Rojas1	Rojas1	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	20	Taiane	Taiane	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	21	Schneider1	Schneider1	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	22	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	23	Ouadah	Ouadah	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	24	Hadjebi1	Hadjebi1	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	25	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	26	Leonardo	Leonardo	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	27	Pedrazza1,2	pedrazza1,2	CD
work_dbbvwgi6and2fokqess5tojy2u	3	28	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	29	Jarbas	Jarbas	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	30	Rodrigues	Rodrigues	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	31	de	de	IN
work_dbbvwgi6and2fokqess5tojy2u	3	32	Oliveira2	Oliveira2	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	33	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	34	Francina	Francina	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	35	Langa3	Langa3	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	36	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	37	Jean	Jean	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	38	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	3	39	Louis	Louis	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	40	Guénet3	Guénet3	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	41	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	42	Joan	Joan	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	43	Duran4	Duran4	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	44	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	45	Josep	Josep	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	46	Maria	Maria	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	47	de	de	IN
work_dbbvwgi6and2fokqess5tojy2u	3	48	Anta4	Anta4	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	49	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	50	Soledad	Soledad	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	51	Alcántara4	Alcántara4	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	52	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	53	Rocio	Rocio	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	54	Ruiz5,6	ruiz5,6	VBP
work_dbbvwgi6and2fokqess5tojy2u	3	55	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	56	Eva	Eva	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	57	María	María	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	58	Pérez	Pérez	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	59	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	3	60	Villegas6	Villegas6	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	61	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	62	Francisco	Francisco	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	63	J.	J.	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	64	Aguilar	Aguilar	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	65	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	3	66	Montilla6	Montilla6	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	67	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	68	Ángel	Ángel	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	69	M.	M.	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	70	Carrión6	Carrión6	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	71	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	72	Jose	Jose	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	73	Angel	Angel	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	74	Armengol6	Armengol6	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	75	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	76	Emma	Emma	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	77	Baple7	Baple7	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	78	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	79	Andrew	Andrew	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	80	H.	H.	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	81	Crosby7	Crosby7	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	82	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	83	Ramon	Ramon	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	84	Bartrons1	Bartrons1	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	85	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	86	Francesc	Francesc	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	87	Ventura1	Ventura1	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	88	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	3	89	Jose	Jose	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	90	Luis	Luis	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	91	Rosa1	Rosa1	VBZ
work_dbbvwgi6and2fokqess5tojy2u	3	92	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	3	93	Departament	Departament	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	94	de	de	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	95	Ciències	Ciències	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	96	Fisiològiques	Fisiològiques	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	97	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	98	IDIBELL	IDIBELL	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	99	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	100	Campus	Campus	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	101	de	de	IN
work_dbbvwgi6and2fokqess5tojy2u	3	102	Bellvitge	Bellvitge	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	103	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	104	Universitat	Universitat	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	105	de	de	IN
work_dbbvwgi6and2fokqess5tojy2u	3	106	Barcelona	Barcelona	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	107	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	108	L’Hospitalet	L’Hospitalet	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	109	de	de	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	110	Llobregat	Llobregat	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	111	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	112	Barcelona	Barcelona	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	113	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	114	Spain	Spain	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	115	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	3	116	Laboratório	Laboratório	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	117	de	de	IN
work_dbbvwgi6and2fokqess5tojy2u	3	118	Pesquisa	Pesquisa	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	119	em	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	3	120	Biofísica	Biofísica	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	121	Celular	Celular	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	122	e	e	VBZ
work_dbbvwgi6and2fokqess5tojy2u	3	123	Inflamação	Inflamação	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	124	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	125	Pontifícia	Pontifícia	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	126	Universidade	Universidade	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	127	Católica	Católica	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	128	do	do	VBP
work_dbbvwgi6and2fokqess5tojy2u	3	129	Rio	Rio	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	130	Grande	Grande	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	131	do	do	VB
work_dbbvwgi6and2fokqess5tojy2u	3	132	Sul	Sul	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	133	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	134	Porto	Porto	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	135	Alegre	Alegre	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	136	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	137	Rio	Rio	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	138	Grande	Grande	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	139	do	do	VBP
work_dbbvwgi6and2fokqess5tojy2u	3	140	Sul	Sul	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	141	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	142	Brazil	Brazil	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	143	3	3	CD
work_dbbvwgi6and2fokqess5tojy2u	3	144	Département	Département	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	145	de	de	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	146	Biologie	Biologie	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	147	du	du	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	148	Développement	Développement	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	149	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	150	Institut	Institut	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	151	Pasteur	Pasteur	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	152	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	153	Paris	Paris	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	154	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	155	France	France	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	156	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	3	157	Departament	Departament	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	158	de	de	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	159	Patologia	Patologia	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	160	i	i	PRP
work_dbbvwgi6and2fokqess5tojy2u	3	161	Terapèutica	Terapèutica	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	162	Experimental	Experimental	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	163	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	164	Campus	Campus	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	165	de	de	IN
work_dbbvwgi6and2fokqess5tojy2u	3	166	Bellvitge	Bellvitge	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	167	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	168	Universitat	Universitat	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	169	de	de	IN
work_dbbvwgi6and2fokqess5tojy2u	3	170	Barcelona	Barcelona	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	171	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	172	L’Hospitalet	L’Hospitalet	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	173	de	de	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	174	Llobregat	Llobregat	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	175	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	176	Barcelona	Barcelona	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	177	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	178	Spain	Spain	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	179	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	3	180	Departamento	Departamento	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	181	de	de	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	182	Bioquímica	Bioquímica	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	183	y	y	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	184	Biología	Biología	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	185	Molecular	Molecular	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	186	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	187	Facultad	Facultad	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	188	de	de	IN
work_dbbvwgi6and2fokqess5tojy2u	3	189	Farmacia	Farmacia	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	190	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	191	Universidad	Universidad	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	192	de	de	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	193	Sevilla	Sevilla	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	194	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	195	Sevilla	Sevilla	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	196	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	197	Spain	Spain	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	198	6	6	CD
work_dbbvwgi6and2fokqess5tojy2u	3	199	Departamento	Departamento	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	200	de	de	IN
work_dbbvwgi6and2fokqess5tojy2u	3	201	Fisiología	Fisiología	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	202	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	203	Anatomía	Anatomía	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	204	y	y	VBZ
work_dbbvwgi6and2fokqess5tojy2u	3	205	Biología	Biología	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	206	Celular	Celular	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	207	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	208	Universidad	Universidad	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	209	Pablo	Pablo	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	210	de	de	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	211	Olavide	Olavide	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	212	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	213	Sevilla	Sevilla	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	214	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	215	Spain	Spain	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	216	7	7	CD
work_dbbvwgi6and2fokqess5tojy2u	3	217	Institute	Institute	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	218	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	3	219	Biomedical	Biomedical	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	220	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	3	221	Clinical	Clinical	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	222	Science	Science	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	223	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	224	University	University	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	225	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	3	226	Exeter	Exeter	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	227	Medical	Medical	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	228	School	School	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	229	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	230	RILD	RILD	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	231	Wellcome	Wellcome	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	232	Wolfson	Wolfson	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	233	Centre	Centre	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	234	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	235	Exeter	Exeter	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	236	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	237	UK	UK	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	238	Correspondence	Correspondence	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	239	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	3	240	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	3	241	Jose	Jose	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	242	Luis	Luis	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	243	Rosa	Rosa	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	244	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	245	email	email	NN
work_dbbvwgi6and2fokqess5tojy2u	3	246	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	3	247	joseluisrosa@ub.edu	joseluisrosa@ub.edu	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	248	Keywords	Keywords	NNPS
work_dbbvwgi6and2fokqess5tojy2u	3	249	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	3	250	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	3	251	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	252	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	3	253	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	254	Angelman	Angelman	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	255	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	3	256	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	257	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	3	258	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	3	259	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	260	behavioural	behavioural	JJ
work_dbbvwgi6and2fokqess5tojy2u	3	261	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	3	262	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	263	Pathology	Pathology	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	264	Section	Section	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	265	Received	receive	VBD
work_dbbvwgi6and2fokqess5tojy2u	3	266	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	3	267	June	June	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	268	07	07	CD
work_dbbvwgi6and2fokqess5tojy2u	3	269	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	270	2016	2016	CD
work_dbbvwgi6and2fokqess5tojy2u	3	271	Accepted	accept	VBN
work_dbbvwgi6and2fokqess5tojy2u	3	272	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	3	273	August	August	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	274	01	01	CD
work_dbbvwgi6and2fokqess5tojy2u	3	275	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	276	2016	2016	CD
work_dbbvwgi6and2fokqess5tojy2u	3	277	Published	publish	VBN
work_dbbvwgi6and2fokqess5tojy2u	3	278	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	3	279	August	August	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	280	12	12	CD
work_dbbvwgi6and2fokqess5tojy2u	3	281	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	3	282	2016	2016	CD
work_dbbvwgi6and2fokqess5tojy2u	3	283	AbstrAct	AbstrAct	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	284	A	a	DT
work_dbbvwgi6and2fokqess5tojy2u	3	285	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	3	286	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	3	287	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	3	288	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	289	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	3	290	has	have	VBZ
work_dbbvwgi6and2fokqess5tojy2u	3	291	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	3	292	linked	link	VBN
work_dbbvwgi6and2fokqess5tojy2u	3	293	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	3	294	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	3	295	severe	severe	JJ
work_dbbvwgi6and2fokqess5tojy2u	3	296	neurodevelopmental	neurodevelopmental	JJ
work_dbbvwgi6and2fokqess5tojy2u	3	297	disorder	disorder	NN
work_dbbvwgi6and2fokqess5tojy2u	3	298	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	3	299	similarities	similarity	NNS
work_dbbvwgi6and2fokqess5tojy2u	3	300	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	3	301	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	3	302	Angelman	Angelman	NNP
work_dbbvwgi6and2fokqess5tojy2u	3	303	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	3	304	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	4	1	This	this	DT
work_dbbvwgi6and2fokqess5tojy2u	4	2	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	4	3	codifies	codify	VBZ
work_dbbvwgi6and2fokqess5tojy2u	4	4	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	4	5	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	4	6	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	4	7	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	4	8	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	4	9	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	4	10	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	4	11	regulates	regulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	4	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	4	13	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	4	14	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	4	15	tumor	tumor	NN
work_dbbvwgi6and2fokqess5tojy2u	4	16	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	4	17	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	4	18	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	4	19	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	4	20	involved	involve	VBN
work_dbbvwgi6and2fokqess5tojy2u	4	21	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	4	22	important	important	JJ
work_dbbvwgi6and2fokqess5tojy2u	4	23	cellular	cellular	JJ
work_dbbvwgi6and2fokqess5tojy2u	4	24	processes	process	NNS
work_dbbvwgi6and2fokqess5tojy2u	4	25	such	such	JJ
work_dbbvwgi6and2fokqess5tojy2u	4	26	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	4	27	DNA	dna	NN
work_dbbvwgi6and2fokqess5tojy2u	4	28	repair	repair	NN
work_dbbvwgi6and2fokqess5tojy2u	4	29	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	4	30	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	4	31	cycle	cycle	NN
work_dbbvwgi6and2fokqess5tojy2u	4	32	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	4	33	cancer	cancer	NN
work_dbbvwgi6and2fokqess5tojy2u	4	34	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	4	35	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	4	36	iron	iron	NN
work_dbbvwgi6and2fokqess5tojy2u	4	37	metabolism	metabolism	NN
work_dbbvwgi6and2fokqess5tojy2u	4	38	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	5	1	Despite	despite	IN
work_dbbvwgi6and2fokqess5tojy2u	5	2	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	5	3	critical	critical	JJ
work_dbbvwgi6and2fokqess5tojy2u	5	4	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	5	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	5	6	HERC2	herc2	NN
work_dbbvwgi6and2fokqess5tojy2u	5	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	5	8	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	5	9	physiological	physiological	JJ
work_dbbvwgi6and2fokqess5tojy2u	5	10	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	5	11	pathological	pathological	JJ
work_dbbvwgi6and2fokqess5tojy2u	5	12	processes	process	NNS
work_dbbvwgi6and2fokqess5tojy2u	5	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	5	14	little	little	JJ
work_dbbvwgi6and2fokqess5tojy2u	5	15	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	5	16	known	know	VBN
work_dbbvwgi6and2fokqess5tojy2u	5	17	about	about	IN
work_dbbvwgi6and2fokqess5tojy2u	5	18	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	5	19	relevance	relevance	NN
work_dbbvwgi6and2fokqess5tojy2u	5	20	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	5	21	vivo	vivo	NNP
work_dbbvwgi6and2fokqess5tojy2u	5	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	6	1	Here	here	RB
work_dbbvwgi6and2fokqess5tojy2u	6	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	6	3	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	6	4	described	describe	VBD
work_dbbvwgi6and2fokqess5tojy2u	6	5	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	6	6	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	6	7	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	6	8	targeted	targeted	JJ
work_dbbvwgi6and2fokqess5tojy2u	6	9	inactivation	inactivation	NN
work_dbbvwgi6and2fokqess5tojy2u	6	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	6	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	6	12	Herc2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	6	13	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	6	14	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	7	1	Homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	7	2	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	7	3	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	7	4	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	7	5	viable	viable	JJ
work_dbbvwgi6and2fokqess5tojy2u	7	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	8	1	Distinct	distinct	JJ
work_dbbvwgi6and2fokqess5tojy2u	8	2	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	8	3	other	other	JJ
work_dbbvwgi6and2fokqess5tojy2u	8	4	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	8	5	ligases	ligase	NNS
work_dbbvwgi6and2fokqess5tojy2u	8	6	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	8	7	interact	interact	VBP
work_dbbvwgi6and2fokqess5tojy2u	8	8	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	8	9	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	8	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	8	11	such	such	JJ
work_dbbvwgi6and2fokqess5tojy2u	8	12	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	8	13	MDM2	MDM2	NNP
work_dbbvwgi6and2fokqess5tojy2u	8	14	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	8	15	MDM4	MDM4	NNP
work_dbbvwgi6and2fokqess5tojy2u	8	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	8	17	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	8	18	depletion	depletion	NN
work_dbbvwgi6and2fokqess5tojy2u	8	19	did	do	VBD
work_dbbvwgi6and2fokqess5tojy2u	8	20	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	8	21	rescue	rescue	VB
work_dbbvwgi6and2fokqess5tojy2u	8	22	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	8	23	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	8	24	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	8	25	homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	8	26	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	8	27	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	9	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	9	2	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	9	3	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	9	4	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	9	5	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	9	6	reduced	reduce	VBN
work_dbbvwgi6and2fokqess5tojy2u	9	7	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	9	8	approximately	approximately	RB
work_dbbvwgi6and2fokqess5tojy2u	9	9	one	one	CD
work_dbbvwgi6and2fokqess5tojy2u	9	10	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	9	11	half	half	NN
work_dbbvwgi6and2fokqess5tojy2u	9	12	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	9	13	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	9	14	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	9	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	10	1	Consequently	consequently	RB
work_dbbvwgi6and2fokqess5tojy2u	10	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	10	3	HERC2	herc2	NN
work_dbbvwgi6and2fokqess5tojy2u	10	4	activities	activity	NNS
work_dbbvwgi6and2fokqess5tojy2u	10	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	10	6	including	include	VBG
work_dbbvwgi6and2fokqess5tojy2u	10	7	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	10	8	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	10	9	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	10	10	stimulation	stimulation	NN
work_dbbvwgi6and2fokqess5tojy2u	10	11	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	10	12	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	10	13	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	10	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	10	15	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	10	16	lower	low	JJR
work_dbbvwgi6and2fokqess5tojy2u	10	17	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	10	18	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	10	19	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	10	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	11	1	A	a	DT
work_dbbvwgi6and2fokqess5tojy2u	11	2	decrease	decrease	NN
work_dbbvwgi6and2fokqess5tojy2u	11	3	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	11	4	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	11	5	activities	activity	NNS
work_dbbvwgi6and2fokqess5tojy2u	11	6	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	11	7	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	11	8	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	11	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	11	10	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	11	11	skin	skin	NN
work_dbbvwgi6and2fokqess5tojy2u	11	12	fibroblasts	fibroblast	NNS
work_dbbvwgi6and2fokqess5tojy2u	11	13	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	11	14	individuals	individual	NNS
work_dbbvwgi6and2fokqess5tojy2u	11	15	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	11	16	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	11	17	Angelman	Angelman	NNP
work_dbbvwgi6and2fokqess5tojy2u	11	18	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	11	19	like	like	JJ
work_dbbvwgi6and2fokqess5tojy2u	11	20	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	11	21	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	11	22	express	express	VBP
work_dbbvwgi6and2fokqess5tojy2u	11	23	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	11	24	unstable	unstable	JJ
work_dbbvwgi6and2fokqess5tojy2u	11	25	mutant	mutant	JJ
work_dbbvwgi6and2fokqess5tojy2u	11	26	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	11	27	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	11	28	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	11	29	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	12	1	Behavioural	behavioural	JJ
work_dbbvwgi6and2fokqess5tojy2u	12	2	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	12	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	12	4	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	12	5	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	12	6	identified	identify	VBD
work_dbbvwgi6and2fokqess5tojy2u	12	7	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	12	8	impaired	impaired	JJ
work_dbbvwgi6and2fokqess5tojy2u	12	9	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	12	10	synchronization	synchronization	NN
work_dbbvwgi6and2fokqess5tojy2u	12	11	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	12	12	normal	normal	JJ
work_dbbvwgi6and2fokqess5tojy2u	12	13	neuromuscular	neuromuscular	JJ
work_dbbvwgi6and2fokqess5tojy2u	12	14	function	function	NN
work_dbbvwgi6and2fokqess5tojy2u	12	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	13	1	This	this	DT
work_dbbvwgi6and2fokqess5tojy2u	13	2	effect	effect	NN
work_dbbvwgi6and2fokqess5tojy2u	13	3	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	13	4	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	13	5	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	13	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	13	7	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	13	8	knockout	knockout	NN
work_dbbvwgi6and2fokqess5tojy2u	13	9	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	13	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	13	11	indicating	indicate	VBG
work_dbbvwgi6and2fokqess5tojy2u	13	12	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	13	13	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	13	14	mechanism	mechanism	NN
work_dbbvwgi6and2fokqess5tojy2u	13	15	independent	independent	JJ
work_dbbvwgi6and2fokqess5tojy2u	13	16	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	13	17	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	13	18	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	13	19	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	13	20	involved	involve	VBN
work_dbbvwgi6and2fokqess5tojy2u	13	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	14	1	Morphological	morphological	JJ
work_dbbvwgi6and2fokqess5tojy2u	14	2	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	14	3	showed	show	VBD
work_dbbvwgi6and2fokqess5tojy2u	14	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	14	5	presence	presence	NN
work_dbbvwgi6and2fokqess5tojy2u	14	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	14	7	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	14	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	14	9	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	14	10	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	14	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	14	12	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	14	13	specific	specific	JJ
work_dbbvwgi6and2fokqess5tojy2u	14	14	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	14	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	14	16	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	14	17	neurons	neuron	NNS
work_dbbvwgi6and2fokqess5tojy2u	14	18	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	14	19	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	14	20	cerebella	cerebella	NN
work_dbbvwgi6and2fokqess5tojy2u	14	21	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	14	22	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	14	23	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	14	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	15	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	15	2	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	15	3	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	15	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	15	5	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	15	6	increase	increase	NN
work_dbbvwgi6and2fokqess5tojy2u	15	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	15	8	autophagosomes	autophagosome	NNS
work_dbbvwgi6and2fokqess5tojy2u	15	9	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	15	10	lysosomes	lysosomes	NNP
work_dbbvwgi6and2fokqess5tojy2u	15	11	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	15	12	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	15	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	16	1	Our	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	16	2	findings	finding	NNS
work_dbbvwgi6and2fokqess5tojy2u	16	3	establish	establish	VBP
work_dbbvwgi6and2fokqess5tojy2u	16	4	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	16	5	crucial	crucial	JJ
work_dbbvwgi6and2fokqess5tojy2u	16	6	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	16	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	16	8	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	16	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	16	10	embryonic	embryonic	NNP
work_dbbvwgi6and2fokqess5tojy2u	16	11	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	16	12	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	16	13	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	16	14	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	16	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	17	1	Research	Research	NNP
work_dbbvwgi6and2fokqess5tojy2u	17	2	Paper	Paper	NNP
work_dbbvwgi6and2fokqess5tojy2u	17	3	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	17	4	Pathology	pathology	NN
work_dbbvwgi6and2fokqess5tojy2u	17	5	Oncotarget56084www.impactjournals.com/oncotarget	oncotarget56084www.impactjournals.com/oncotarget	NN
work_dbbvwgi6and2fokqess5tojy2u	17	6	INtrODUctION	INtrODUctION	.
work_dbbvwgi6and2fokqess5tojy2u	17	7	Angelman	angelman	NN
work_dbbvwgi6and2fokqess5tojy2u	17	8	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	17	9	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	17	10	AS	AS	NNP
work_dbbvwgi6and2fokqess5tojy2u	17	11	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	17	12	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	17	13	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	17	14	severe	severe	JJ
work_dbbvwgi6and2fokqess5tojy2u	17	15	neurodevelopmental	neurodevelopmental	JJ
work_dbbvwgi6and2fokqess5tojy2u	17	16	disorder	disorder	NN
work_dbbvwgi6and2fokqess5tojy2u	17	17	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	17	18	occurs	occur	VBZ
work_dbbvwgi6and2fokqess5tojy2u	17	19	in	in	RB
work_dbbvwgi6and2fokqess5tojy2u	17	20	approximately	approximately	RB
work_dbbvwgi6and2fokqess5tojy2u	17	21	one	one	CD
work_dbbvwgi6and2fokqess5tojy2u	17	22	out	out	IN
work_dbbvwgi6and2fokqess5tojy2u	17	23	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	17	24	every	every	DT
work_dbbvwgi6and2fokqess5tojy2u	17	25	12,000	12,000	CD
work_dbbvwgi6and2fokqess5tojy2u	17	26	births	birth	NNS
work_dbbvwgi6and2fokqess5tojy2u	17	27	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	18	1	Patients	patient	NNS
work_dbbvwgi6and2fokqess5tojy2u	18	2	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	18	3	AS	as	IN
work_dbbvwgi6and2fokqess5tojy2u	18	4	exhibit	exhibit	NN
work_dbbvwgi6and2fokqess5tojy2u	18	5	developmental	developmental	JJ
work_dbbvwgi6and2fokqess5tojy2u	18	6	delay	delay	NN
work_dbbvwgi6and2fokqess5tojy2u	18	7	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	18	8	speech	speech	NN
work_dbbvwgi6and2fokqess5tojy2u	18	9	impairments	impairment	NNS
work_dbbvwgi6and2fokqess5tojy2u	18	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	18	11	intellectual	intellectual	JJ
work_dbbvwgi6and2fokqess5tojy2u	18	12	disability	disability	NN
work_dbbvwgi6and2fokqess5tojy2u	18	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	18	14	epilepsy	epilepsy	NN
work_dbbvwgi6and2fokqess5tojy2u	18	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	18	16	abnormal	abnormal	JJ
work_dbbvwgi6and2fokqess5tojy2u	18	17	electroencephalograms	electroencephalogram	NNS
work_dbbvwgi6and2fokqess5tojy2u	18	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	18	19	puppet	puppet	NN
work_dbbvwgi6and2fokqess5tojy2u	18	20	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	18	21	like	like	JJ
work_dbbvwgi6and2fokqess5tojy2u	18	22	ataxic	ataxic	JJ
work_dbbvwgi6and2fokqess5tojy2u	18	23	movements	movement	NNS
work_dbbvwgi6and2fokqess5tojy2u	18	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	18	25	prognathism	prognathism	NN
work_dbbvwgi6and2fokqess5tojy2u	18	26	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	18	27	tongue	tongue	NN
work_dbbvwgi6and2fokqess5tojy2u	18	28	protrusion	protrusion	NN
work_dbbvwgi6and2fokqess5tojy2u	18	29	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	18	30	paroxysms	paroxysm	NNS
work_dbbvwgi6and2fokqess5tojy2u	18	31	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	18	32	laughter	laughter	NN
work_dbbvwgi6and2fokqess5tojy2u	18	33	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	18	34	abnormal	abnormal	JJ
work_dbbvwgi6and2fokqess5tojy2u	18	35	sleep	sleep	NN
work_dbbvwgi6and2fokqess5tojy2u	18	36	patterns	pattern	NNS
work_dbbvwgi6and2fokqess5tojy2u	18	37	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	18	38	hyperactivity	hyperactivity	NN
work_dbbvwgi6and2fokqess5tojy2u	18	39	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	18	40	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	18	41	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	18	42	high	high	JJ
work_dbbvwgi6and2fokqess5tojy2u	18	43	prevalence	prevalence	NN
work_dbbvwgi6and2fokqess5tojy2u	18	44	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	18	45	autism	autism	NN
work_dbbvwgi6and2fokqess5tojy2u	18	46	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	18	47	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	18	48	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	18	49	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	18	50	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	18	51	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	19	1	Genetic	genetic	JJ
work_dbbvwgi6and2fokqess5tojy2u	19	2	studies	study	NNS
work_dbbvwgi6and2fokqess5tojy2u	19	3	revealed	reveal	VBD
work_dbbvwgi6and2fokqess5tojy2u	19	4	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	19	5	AS	AS	NNP
work_dbbvwgi6and2fokqess5tojy2u	19	6	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	19	7	associated	associate	VBN
work_dbbvwgi6and2fokqess5tojy2u	19	8	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	19	9	maternal	maternal	JJ
work_dbbvwgi6and2fokqess5tojy2u	19	10	deletions	deletion	NNS
work_dbbvwgi6and2fokqess5tojy2u	19	11	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	19	12	chromosome	chromosome	NN
work_dbbvwgi6and2fokqess5tojy2u	19	13	15q11-q13	15q11-q13	CD
work_dbbvwgi6and2fokqess5tojy2u	19	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	19	15	paternal	paternal	JJ
work_dbbvwgi6and2fokqess5tojy2u	19	16	chromosome	chromosome	NN
work_dbbvwgi6and2fokqess5tojy2u	19	17	15	15	CD
work_dbbvwgi6and2fokqess5tojy2u	19	18	uniparental	uniparental	JJ
work_dbbvwgi6and2fokqess5tojy2u	19	19	disomy	disomy	NN
work_dbbvwgi6and2fokqess5tojy2u	19	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	19	21	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	19	22	rare	rare	JJ
work_dbbvwgi6and2fokqess5tojy2u	19	23	imprinting	imprinting	NN
work_dbbvwgi6and2fokqess5tojy2u	19	24	defects	defect	NNS
work_dbbvwgi6and2fokqess5tojy2u	19	25	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	19	26	affect	affect	VBP
work_dbbvwgi6and2fokqess5tojy2u	19	27	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	19	28	transcription	transcription	NN
work_dbbvwgi6and2fokqess5tojy2u	19	29	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	19	30	genes	gene	NNS
work_dbbvwgi6and2fokqess5tojy2u	19	31	within	within	IN
work_dbbvwgi6and2fokqess5tojy2u	19	32	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	19	33	15q11-q13	15q11-q13	CD
work_dbbvwgi6and2fokqess5tojy2u	19	34	region	region	NN
work_dbbvwgi6and2fokqess5tojy2u	19	35	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	20	1	Specific	specific	JJ
work_dbbvwgi6and2fokqess5tojy2u	20	2	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	20	3	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	20	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	20	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	20	6	function	function	NN
work_dbbvwgi6and2fokqess5tojy2u	20	7	mutations	mutation	NNS
work_dbbvwgi6and2fokqess5tojy2u	20	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	20	9	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	20	10	maternally	maternally	RB
work_dbbvwgi6and2fokqess5tojy2u	20	11	inherited	inherit	VBN
work_dbbvwgi6and2fokqess5tojy2u	20	12	UBE3A	ube3a	CD
work_dbbvwgi6and2fokqess5tojy2u	20	13	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	20	14	which	which	WDT
work_dbbvwgi6and2fokqess5tojy2u	20	15	resides	reside	VBZ
work_dbbvwgi6and2fokqess5tojy2u	20	16	within	within	IN
work_dbbvwgi6and2fokqess5tojy2u	20	17	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	20	18	chromosomal	chromosomal	JJ
work_dbbvwgi6and2fokqess5tojy2u	20	19	region	region	NN
work_dbbvwgi6and2fokqess5tojy2u	20	20	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	20	21	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	20	22	identified	identify	VBN
work_dbbvwgi6and2fokqess5tojy2u	20	23	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	20	24	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	20	25	subset	subset	NN
work_dbbvwgi6and2fokqess5tojy2u	20	26	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	20	27	affected	affect	VBN
work_dbbvwgi6and2fokqess5tojy2u	20	28	individuals	individual	NNS
work_dbbvwgi6and2fokqess5tojy2u	20	29	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	20	30	3	3	CD
work_dbbvwgi6and2fokqess5tojy2u	20	31	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	20	32	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	21	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	21	2	UBE3A	ube3a	CD
work_dbbvwgi6and2fokqess5tojy2u	21	3	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	21	4	encodes	encode	VBZ
work_dbbvwgi6and2fokqess5tojy2u	21	5	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	21	6	E3	E3	NNP
work_dbbvwgi6and2fokqess5tojy2u	21	7	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	21	8	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	21	9	called	call	VBD
work_dbbvwgi6and2fokqess5tojy2u	21	10	UBE3A	ube3a	CD
work_dbbvwgi6and2fokqess5tojy2u	21	11	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	21	12	E6-associated	e6-associate	VBN
work_dbbvwgi6and2fokqess5tojy2u	21	13	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	21	14	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	21	15	E6AP	E6AP	NNP
work_dbbvwgi6and2fokqess5tojy2u	21	16	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	21	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	22	1	More	more	RBR
work_dbbvwgi6and2fokqess5tojy2u	22	2	recently	recently	RB
work_dbbvwgi6and2fokqess5tojy2u	22	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	22	4	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	22	5	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	22	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	22	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	22	8	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	22	9	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	22	10	has	have	VBZ
work_dbbvwgi6and2fokqess5tojy2u	22	11	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	22	12	linked	link	VBN
work_dbbvwgi6and2fokqess5tojy2u	22	13	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	22	14	neurodevelopmental	neurodevelopmental	NNP
work_dbbvwgi6and2fokqess5tojy2u	22	15	delay	delay	NN
work_dbbvwgi6and2fokqess5tojy2u	22	16	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	22	17	dysfunction	dysfunction	NN
work_dbbvwgi6and2fokqess5tojy2u	22	18	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	22	19	both	both	DT
work_dbbvwgi6and2fokqess5tojy2u	22	20	AS	as	IN
work_dbbvwgi6and2fokqess5tojy2u	22	21	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	22	22	autism	autism	NN
work_dbbvwgi6and2fokqess5tojy2u	22	23	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	22	24	spectrum	spectrum	NN
work_dbbvwgi6and2fokqess5tojy2u	22	25	disorders	disorder	NNS
work_dbbvwgi6and2fokqess5tojy2u	22	26	among	among	IN
work_dbbvwgi6and2fokqess5tojy2u	22	27	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	22	28	Old	Old	NNP
work_dbbvwgi6and2fokqess5tojy2u	22	29	Order	order	NN
work_dbbvwgi6and2fokqess5tojy2u	22	30	Amish	Amish	NNP
work_dbbvwgi6and2fokqess5tojy2u	22	31	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	22	32	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	22	33	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	22	34	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	22	35	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	22	36	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	23	1	Molecular	molecular	JJ
work_dbbvwgi6and2fokqess5tojy2u	23	2	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	23	3	associated	associate	VBD
work_dbbvwgi6and2fokqess5tojy2u	23	4	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	23	5	missense	missense	NN
work_dbbvwgi6and2fokqess5tojy2u	23	6	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	23	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	23	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	23	9	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	23	10	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	23	11	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	23	12	c.1781C	c.1781C	NNP
work_dbbvwgi6and2fokqess5tojy2u	23	13	>	>	XX
work_dbbvwgi6and2fokqess5tojy2u	23	14	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	23	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	23	16	p	p	NNP
work_dbbvwgi6and2fokqess5tojy2u	23	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	23	18	Pro594Leu	pro594leu	LS
work_dbbvwgi6and2fokqess5tojy2u	23	19	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	23	20	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	23	21	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	23	22	disease	disease	NN
work_dbbvwgi6and2fokqess5tojy2u	23	23	phenotype	phenotype	NN
work_dbbvwgi6and2fokqess5tojy2u	23	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	24	1	Although	although	IN
work_dbbvwgi6and2fokqess5tojy2u	24	2	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	24	3	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	24	4	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	24	5	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	24	6	resides	reside	VBZ
work_dbbvwgi6and2fokqess5tojy2u	24	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	24	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	24	9	15q11-q13	15q11-q13	CD
work_dbbvwgi6and2fokqess5tojy2u	24	10	region	region	NN
work_dbbvwgi6and2fokqess5tojy2u	24	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	24	12	it	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	24	13	seems	seem	VBZ
work_dbbvwgi6and2fokqess5tojy2u	24	14	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	24	15	it	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	24	16	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	24	17	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	24	18	imprinted	imprint	VBN
work_dbbvwgi6and2fokqess5tojy2u	24	19	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	24	20	6	6	CD
work_dbbvwgi6and2fokqess5tojy2u	24	21	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	24	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	25	1	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	25	2	encodes	encode	VBZ
work_dbbvwgi6and2fokqess5tojy2u	25	3	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	25	4	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	25	5	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	25	6	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	25	7	binds	bind	VBZ
work_dbbvwgi6and2fokqess5tojy2u	25	8	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	25	9	UBE3A	ube3a	CD
work_dbbvwgi6and2fokqess5tojy2u	25	10	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	25	11	stimulates	stimulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	25	12	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	25	13	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	25	14	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	25	15	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	25	16	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	25	17	7	7	CD
work_dbbvwgi6and2fokqess5tojy2u	25	18	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	25	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	26	1	Deregulation	deregulation	NN
work_dbbvwgi6and2fokqess5tojy2u	26	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	26	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	26	4	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	26	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	26	6	UBE3A	ube3a	CD
work_dbbvwgi6and2fokqess5tojy2u	26	7	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	26	8	well	well	RB
work_dbbvwgi6and2fokqess5tojy2u	26	9	recognized	recognize	VBN
work_dbbvwgi6and2fokqess5tojy2u	26	10	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	26	11	contributing	contribute	VBG
work_dbbvwgi6and2fokqess5tojy2u	26	12	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	26	13	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	26	14	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	26	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	26	16	AS	AS	NNP
work_dbbvwgi6and2fokqess5tojy2u	26	17	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	26	18	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	26	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	26	20	3	3	CD
work_dbbvwgi6and2fokqess5tojy2u	26	21	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	26	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	27	1	Thus	thus	RB
work_dbbvwgi6and2fokqess5tojy2u	27	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	27	3	disruption	disruption	NN
work_dbbvwgi6and2fokqess5tojy2u	27	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	27	5	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	27	6	function	function	NN
work_dbbvwgi6and2fokqess5tojy2u	27	7	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	27	8	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	27	9	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	27	10	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	27	11	associated	associate	VBN
work_dbbvwgi6and2fokqess5tojy2u	27	12	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	27	13	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	27	14	reduction	reduction	NN
work_dbbvwgi6and2fokqess5tojy2u	27	15	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	27	16	UBE3A	ube3a	CD
work_dbbvwgi6and2fokqess5tojy2u	27	17	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	27	18	resulting	result	VBG
work_dbbvwgi6and2fokqess5tojy2u	27	19	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	27	20	neurodevelopmental	neurodevelopmental	JJ
work_dbbvwgi6and2fokqess5tojy2u	27	21	delay	delay	NN
work_dbbvwgi6and2fokqess5tojy2u	27	22	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	27	23	Angelman	angelman	NN
work_dbbvwgi6and2fokqess5tojy2u	27	24	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	27	25	like	like	JJ
work_dbbvwgi6and2fokqess5tojy2u	27	26	features	feature	NNS
work_dbbvwgi6and2fokqess5tojy2u	27	27	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	27	28	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	27	29	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	27	30	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	27	31	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	27	32	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	28	1	Genetic	genetic	JJ
work_dbbvwgi6and2fokqess5tojy2u	28	2	variations	variation	NNS
work_dbbvwgi6and2fokqess5tojy2u	28	3	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	28	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	28	5	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	28	6	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	28	7	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	28	8	associated	associate	VBN
work_dbbvwgi6and2fokqess5tojy2u	28	9	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	28	10	eye	eye	NN
work_dbbvwgi6and2fokqess5tojy2u	28	11	pigmentation	pigmentation	NN
work_dbbvwgi6and2fokqess5tojy2u	28	12	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	29	1	Although	although	IN
work_dbbvwgi6and2fokqess5tojy2u	29	2	multiple	multiple	JJ
work_dbbvwgi6and2fokqess5tojy2u	29	3	genes	gene	NNS
work_dbbvwgi6and2fokqess5tojy2u	29	4	contribute	contribute	VBP
work_dbbvwgi6and2fokqess5tojy2u	29	5	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	29	6	eye	eye	NN
work_dbbvwgi6and2fokqess5tojy2u	29	7	colour	colour	NN
work_dbbvwgi6and2fokqess5tojy2u	29	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	29	9	humans	human	NNS
work_dbbvwgi6and2fokqess5tojy2u	29	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	29	11	most	most	JJS
work_dbbvwgi6and2fokqess5tojy2u	29	12	variation	variation	NN
work_dbbvwgi6and2fokqess5tojy2u	29	13	can	can	MD
work_dbbvwgi6and2fokqess5tojy2u	29	14	be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	29	15	attributed	attribute	VBN
work_dbbvwgi6and2fokqess5tojy2u	29	16	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	29	17	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	29	18	strong	strong	JJ
work_dbbvwgi6and2fokqess5tojy2u	29	19	interaction	interaction	NN
work_dbbvwgi6and2fokqess5tojy2u	29	20	between	between	IN
work_dbbvwgi6and2fokqess5tojy2u	29	21	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	29	22	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	29	23	adjacent	adjacent	JJ
work_dbbvwgi6and2fokqess5tojy2u	29	24	OCA2	OCA2	NNP
work_dbbvwgi6and2fokqess5tojy2u	29	25	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	29	26	chromosome	chromosome	NN
work_dbbvwgi6and2fokqess5tojy2u	29	27	15	15	CD
work_dbbvwgi6and2fokqess5tojy2u	29	28	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	29	29	8	8	CD
work_dbbvwgi6and2fokqess5tojy2u	29	30	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	29	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	30	1	A	a	DT
work_dbbvwgi6and2fokqess5tojy2u	30	2	distal	distal	JJ
work_dbbvwgi6and2fokqess5tojy2u	30	3	regulatory	regulatory	JJ
work_dbbvwgi6and2fokqess5tojy2u	30	4	element	element	NN
work_dbbvwgi6and2fokqess5tojy2u	30	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	30	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	30	7	OCA2	OCA2	NNP
work_dbbvwgi6and2fokqess5tojy2u	30	8	promoter	promoter	NN
work_dbbvwgi6and2fokqess5tojy2u	30	9	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	30	10	within	within	IN
work_dbbvwgi6and2fokqess5tojy2u	30	11	intron	intron	NNP
work_dbbvwgi6and2fokqess5tojy2u	30	12	86	86	CD
work_dbbvwgi6and2fokqess5tojy2u	30	13	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	30	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	30	15	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	30	16	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	30	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	30	18	three	three	CD
work_dbbvwgi6and2fokqess5tojy2u	30	19	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	30	20	sequence	sequence	NN
work_dbbvwgi6and2fokqess5tojy2u	30	21	variants	variant	NNS
work_dbbvwgi6and2fokqess5tojy2u	30	22	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	30	23	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	30	24	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	30	25	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	30	26	identified	identify	VBN
work_dbbvwgi6and2fokqess5tojy2u	30	27	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	30	28	such	such	JJ
work_dbbvwgi6and2fokqess5tojy2u	30	29	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	30	30	predictors	predictor	NNS
work_dbbvwgi6and2fokqess5tojy2u	30	31	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	30	32	eye	eye	NN
work_dbbvwgi6and2fokqess5tojy2u	30	33	colour	colour	NN
work_dbbvwgi6and2fokqess5tojy2u	30	34	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	30	35	humans	human	NNS
work_dbbvwgi6and2fokqess5tojy2u	30	36	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	30	37	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	30	38	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	30	39	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	30	40	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	30	41	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	31	1	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	31	2	belongs	belong	VBZ
work_dbbvwgi6and2fokqess5tojy2u	31	3	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	31	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	31	5	HERC	HERC	NNP
work_dbbvwgi6and2fokqess5tojy2u	31	6	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	31	7	family	family	NN
work_dbbvwgi6and2fokqess5tojy2u	31	8	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	31	9	encodes	encode	VBZ
work_dbbvwgi6and2fokqess5tojy2u	31	10	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	31	11	group	group	NN
work_dbbvwgi6and2fokqess5tojy2u	31	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	31	13	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	31	14	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	31	15	contain	contain	VBP
work_dbbvwgi6and2fokqess5tojy2u	31	16	multiple	multiple	JJ
work_dbbvwgi6and2fokqess5tojy2u	31	17	structural	structural	JJ
work_dbbvwgi6and2fokqess5tojy2u	31	18	domains	domain	NNS
work_dbbvwgi6and2fokqess5tojy2u	31	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	32	1	All	all	DT
work_dbbvwgi6and2fokqess5tojy2u	32	2	members	member	NNS
work_dbbvwgi6and2fokqess5tojy2u	32	3	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	32	4	at	at	RB
work_dbbvwgi6and2fokqess5tojy2u	32	5	least	least	RBS
work_dbbvwgi6and2fokqess5tojy2u	32	6	one	one	CD
work_dbbvwgi6and2fokqess5tojy2u	32	7	copy	copy	NN
work_dbbvwgi6and2fokqess5tojy2u	32	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	32	9	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	32	10	N	n	CD
work_dbbvwgi6and2fokqess5tojy2u	32	11	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	32	12	terminal	terminal	NN
work_dbbvwgi6and2fokqess5tojy2u	32	13	region	region	NN
work_dbbvwgi6and2fokqess5tojy2u	32	14	showing	show	VBG
work_dbbvwgi6and2fokqess5tojy2u	32	15	homology	homology	NN
work_dbbvwgi6and2fokqess5tojy2u	32	16	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	32	17	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	32	18	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	32	19	cycle	cycle	NN
work_dbbvwgi6and2fokqess5tojy2u	32	20	regulator	regulator	NN
work_dbbvwgi6and2fokqess5tojy2u	32	21	RCC1	RCC1	NNP
work_dbbvwgi6and2fokqess5tojy2u	32	22	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	32	23	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	32	24	C	c	NN
work_dbbvwgi6and2fokqess5tojy2u	32	25	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	32	26	terminal	terminal	JJ
work_dbbvwgi6and2fokqess5tojy2u	32	27	HECT	HECT	NNP
work_dbbvwgi6and2fokqess5tojy2u	32	28	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	32	29	homologous	homologous	JJ
work_dbbvwgi6and2fokqess5tojy2u	32	30	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	32	31	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	32	32	E6-AP	E6-AP	NNP
work_dbbvwgi6and2fokqess5tojy2u	32	33	carboxyl	carboxyl	NN
work_dbbvwgi6and2fokqess5tojy2u	32	34	terminus	terminus	NN
work_dbbvwgi6and2fokqess5tojy2u	32	35	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	32	36	domain	domain	NN
work_dbbvwgi6and2fokqess5tojy2u	32	37	found	find	VBN
work_dbbvwgi6and2fokqess5tojy2u	32	38	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	32	39	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	32	40	number	number	NN
work_dbbvwgi6and2fokqess5tojy2u	32	41	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	32	42	E3	e3	NN
work_dbbvwgi6and2fokqess5tojy2u	32	43	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	32	44	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	32	45	ligases	ligase	NNS
work_dbbvwgi6and2fokqess5tojy2u	32	46	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	33	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	33	2	two	two	CD
work_dbbvwgi6and2fokqess5tojy2u	33	3	domains	domain	NNS
work_dbbvwgi6and2fokqess5tojy2u	33	4	define	define	VBP
work_dbbvwgi6and2fokqess5tojy2u	33	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	33	6	HERC	HERC	NNP
work_dbbvwgi6and2fokqess5tojy2u	33	7	family	family	NN
work_dbbvwgi6and2fokqess5tojy2u	33	8	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	33	9	HERC	HERC	NNP
work_dbbvwgi6and2fokqess5tojy2u	33	10	=	=	SYM
work_dbbvwgi6and2fokqess5tojy2u	33	11	HECT	HECT	NNP
work_dbbvwgi6and2fokqess5tojy2u	33	12	+	+	SYM
work_dbbvwgi6and2fokqess5tojy2u	33	13	RCC1	RCC1	NNP
work_dbbvwgi6and2fokqess5tojy2u	33	14	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	33	15	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	33	16	11	11	CD
work_dbbvwgi6and2fokqess5tojy2u	33	17	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	33	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	34	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	34	2	humans	human	NNS
work_dbbvwgi6and2fokqess5tojy2u	34	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	34	4	six	six	CD
work_dbbvwgi6and2fokqess5tojy2u	34	5	members	member	NNS
work_dbbvwgi6and2fokqess5tojy2u	34	6	form	form	VBP
work_dbbvwgi6and2fokqess5tojy2u	34	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	34	8	HERC	HERC	NNP
work_dbbvwgi6and2fokqess5tojy2u	34	9	family	family	NN
work_dbbvwgi6and2fokqess5tojy2u	34	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	35	1	They	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	35	2	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	35	3	classified	classify	VBN
work_dbbvwgi6and2fokqess5tojy2u	35	4	into	into	IN
work_dbbvwgi6and2fokqess5tojy2u	35	5	two	two	CD
work_dbbvwgi6and2fokqess5tojy2u	35	6	groups	group	NNS
work_dbbvwgi6and2fokqess5tojy2u	35	7	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	35	8	large	large	JJ
work_dbbvwgi6and2fokqess5tojy2u	35	9	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	35	10	HERC1	herc1	NN
work_dbbvwgi6and2fokqess5tojy2u	35	11	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	35	12	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	35	13	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	35	14	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	35	15	small	small	JJ
work_dbbvwgi6and2fokqess5tojy2u	35	16	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	35	17	HERC3	HERC3	NNS
work_dbbvwgi6and2fokqess5tojy2u	35	18	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	35	19	6	6	CD
work_dbbvwgi6and2fokqess5tojy2u	35	20	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	35	21	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	35	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	36	1	Structurally	structurally	RB
work_dbbvwgi6and2fokqess5tojy2u	36	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	36	3	small	small	JJ
work_dbbvwgi6and2fokqess5tojy2u	36	4	HERC	HERC	NNP
work_dbbvwgi6and2fokqess5tojy2u	36	5	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	36	6	contain	contain	VBP
work_dbbvwgi6and2fokqess5tojy2u	36	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	36	8	two	two	CD
work_dbbvwgi6and2fokqess5tojy2u	36	9	characteristic	characteristic	JJ
work_dbbvwgi6and2fokqess5tojy2u	36	10	domains	domain	NNS
work_dbbvwgi6and2fokqess5tojy2u	36	11	HECT	HECT	NNP
work_dbbvwgi6and2fokqess5tojy2u	36	12	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	36	13	RCC1	RCC1	NNP
work_dbbvwgi6and2fokqess5tojy2u	36	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	36	15	whereas	whereas	IN
work_dbbvwgi6and2fokqess5tojy2u	36	16	large	large	JJ
work_dbbvwgi6and2fokqess5tojy2u	36	17	HERC	HERC	NNP
work_dbbvwgi6and2fokqess5tojy2u	36	18	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	36	19	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	36	20	giant	giant	JJ
work_dbbvwgi6and2fokqess5tojy2u	36	21	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	36	22	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	36	23	approximately	approximately	RB
work_dbbvwgi6and2fokqess5tojy2u	36	24	5,000	5,000	CD
work_dbbvwgi6and2fokqess5tojy2u	36	25	amino	amino	JJ
work_dbbvwgi6and2fokqess5tojy2u	36	26	acid	acid	NN
work_dbbvwgi6and2fokqess5tojy2u	36	27	residues	residue	NNS
work_dbbvwgi6and2fokqess5tojy2u	36	28	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	36	29	containing	contain	VBG
work_dbbvwgi6and2fokqess5tojy2u	36	30	additional	additional	JJ
work_dbbvwgi6and2fokqess5tojy2u	36	31	domains	domain	NNS
work_dbbvwgi6and2fokqess5tojy2u	36	32	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	36	33	including	include	VBG
work_dbbvwgi6and2fokqess5tojy2u	36	34	several	several	JJ
work_dbbvwgi6and2fokqess5tojy2u	36	35	RCC1	RCC1	NNP
work_dbbvwgi6and2fokqess5tojy2u	36	36	domains	domain	NNS
work_dbbvwgi6and2fokqess5tojy2u	36	37	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	37	1	Functionally	functionally	RB
work_dbbvwgi6and2fokqess5tojy2u	37	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	37	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	37	4	HERC	HERC	NNP
work_dbbvwgi6and2fokqess5tojy2u	37	5	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	37	6	family	family	NN
work_dbbvwgi6and2fokqess5tojy2u	37	7	regulates	regulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	37	8	ubiquitination	ubiquitination	NN
work_dbbvwgi6and2fokqess5tojy2u	37	9	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	37	10	ISGylation	isgylation	NN
work_dbbvwgi6and2fokqess5tojy2u	37	11	processes	process	NNS
work_dbbvwgi6and2fokqess5tojy2u	37	12	associated	associate	VBN
work_dbbvwgi6and2fokqess5tojy2u	37	13	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	37	14	membrane	membrane	NN
work_dbbvwgi6and2fokqess5tojy2u	37	15	trafficking	trafficking	NN
work_dbbvwgi6and2fokqess5tojy2u	37	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	37	17	immune	immune	JJ
work_dbbvwgi6and2fokqess5tojy2u	37	18	response	response	NN
work_dbbvwgi6and2fokqess5tojy2u	37	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	37	20	DNA	dna	NN
work_dbbvwgi6and2fokqess5tojy2u	37	21	repair	repair	NN
work_dbbvwgi6and2fokqess5tojy2u	37	22	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	37	23	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	37	24	stress	stress	NN
work_dbbvwgi6and2fokqess5tojy2u	37	25	response	response	NN
work_dbbvwgi6and2fokqess5tojy2u	37	26	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	37	27	cancer	cancer	NN
work_dbbvwgi6and2fokqess5tojy2u	37	28	biology	biology	NN
work_dbbvwgi6and2fokqess5tojy2u	37	29	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	37	30	11	11	CD
work_dbbvwgi6and2fokqess5tojy2u	37	31	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	37	32	20	20	CD
work_dbbvwgi6and2fokqess5tojy2u	37	33	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	37	34	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	38	1	Recently	recently	RB
work_dbbvwgi6and2fokqess5tojy2u	38	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	38	3	several	several	JJ
work_dbbvwgi6and2fokqess5tojy2u	38	4	substrates	substrate	NNS
work_dbbvwgi6and2fokqess5tojy2u	38	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	38	6	HERC2	HERC2	NNS
work_dbbvwgi6and2fokqess5tojy2u	38	7	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	38	8	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	38	9	identified	identify	VBN
work_dbbvwgi6and2fokqess5tojy2u	38	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	39	1	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	39	2	targets	target	NNS
work_dbbvwgi6and2fokqess5tojy2u	39	3	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	39	4	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	39	5	dependent	dependent	JJ
work_dbbvwgi6and2fokqess5tojy2u	39	6	proteasomal	proteasomal	JJ
work_dbbvwgi6and2fokqess5tojy2u	39	7	degradation	degradation	NN
work_dbbvwgi6and2fokqess5tojy2u	39	8	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	39	9	xeroderma	xeroderma	NNP
work_dbbvwgi6and2fokqess5tojy2u	39	10	pigmentosa	pigmentosa	NNP
work_dbbvwgi6and2fokqess5tojy2u	39	11	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	39	12	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	39	13	XPA	XPA	NNP
work_dbbvwgi6and2fokqess5tojy2u	39	14	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	39	15	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	39	16	circadian	circadian	JJ
work_dbbvwgi6and2fokqess5tojy2u	39	17	control	control	NN
work_dbbvwgi6and2fokqess5tojy2u	39	18	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	39	19	nucleotide	nucleotide	JJ
work_dbbvwgi6and2fokqess5tojy2u	39	20	excision	excision	NN
work_dbbvwgi6and2fokqess5tojy2u	39	21	repair	repair	NN
work_dbbvwgi6and2fokqess5tojy2u	39	22	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	39	23	21	21	CD
work_dbbvwgi6and2fokqess5tojy2u	39	24	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	39	25	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	39	26	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	39	27	breast	breast	NN
work_dbbvwgi6and2fokqess5tojy2u	39	28	cancer	cancer	NN
work_dbbvwgi6and2fokqess5tojy2u	39	29	suppressor	suppressor	NN
work_dbbvwgi6and2fokqess5tojy2u	39	30	BRCA1	brca1	NN
work_dbbvwgi6and2fokqess5tojy2u	39	31	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	39	32	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	39	33	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	39	34	cycle	cycle	NN
work_dbbvwgi6and2fokqess5tojy2u	39	35	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	39	36	22	22	CD
work_dbbvwgi6and2fokqess5tojy2u	39	37	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	39	38	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	40	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	40	2	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	40	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	40	4	together	together	RB
work_dbbvwgi6and2fokqess5tojy2u	40	5	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	40	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	40	7	interaction	interaction	NN
work_dbbvwgi6and2fokqess5tojy2u	40	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	40	9	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	40	10	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	40	11	RNF8	RNF8	NNP
work_dbbvwgi6and2fokqess5tojy2u	40	12	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	40	13	23	23	CD
work_dbbvwgi6and2fokqess5tojy2u	40	14	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	40	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	40	16	indicate	indicate	VBP
work_dbbvwgi6and2fokqess5tojy2u	40	17	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	40	18	regulatory	regulatory	JJ
work_dbbvwgi6and2fokqess5tojy2u	40	19	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	40	20	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	40	21	HERC2	herc2	NN
work_dbbvwgi6and2fokqess5tojy2u	40	22	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	40	23	DNA	dna	NN
work_dbbvwgi6and2fokqess5tojy2u	40	24	repair	repair	NN
work_dbbvwgi6and2fokqess5tojy2u	40	25	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	40	26	nucleotide	nucleotide	JJ
work_dbbvwgi6and2fokqess5tojy2u	40	27	excision	excision	NN
work_dbbvwgi6and2fokqess5tojy2u	40	28	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	40	29	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	40	30	homologous	homologous	JJ
work_dbbvwgi6and2fokqess5tojy2u	40	31	recombination	recombination	NN
work_dbbvwgi6and2fokqess5tojy2u	40	32	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	40	33	DNA	DNA	NNP
work_dbbvwgi6and2fokqess5tojy2u	40	34	double	double	JJ
work_dbbvwgi6and2fokqess5tojy2u	40	35	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	40	36	strand	strand	NN
work_dbbvwgi6and2fokqess5tojy2u	40	37	breakage	breakage	NN
work_dbbvwgi6and2fokqess5tojy2u	40	38	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	41	1	More	more	RBR
work_dbbvwgi6and2fokqess5tojy2u	41	2	recently	recently	RB
work_dbbvwgi6and2fokqess5tojy2u	41	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	41	4	other	other	JJ
work_dbbvwgi6and2fokqess5tojy2u	41	5	substrates	substrate	NNS
work_dbbvwgi6and2fokqess5tojy2u	41	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	41	7	such	such	JJ
work_dbbvwgi6and2fokqess5tojy2u	41	8	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	41	9	NEURL4	neurl4	CD
work_dbbvwgi6and2fokqess5tojy2u	41	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	41	11	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	41	12	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	41	13	FBXL5	FBXL5	NNS
work_dbbvwgi6and2fokqess5tojy2u	41	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	41	15	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	41	16	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	41	17	reported	report	VBN
work_dbbvwgi6and2fokqess5tojy2u	41	18	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	41	19	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	41	20	indicate	indicate	VBP
work_dbbvwgi6and2fokqess5tojy2u	41	21	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	41	22	participation	participation	NN
work_dbbvwgi6and2fokqess5tojy2u	41	23	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	41	24	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	41	25	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	41	26	other	other	JJ
work_dbbvwgi6and2fokqess5tojy2u	41	27	important	important	JJ
work_dbbvwgi6and2fokqess5tojy2u	41	28	cellular	cellular	JJ
work_dbbvwgi6and2fokqess5tojy2u	41	29	processes	process	NNS
work_dbbvwgi6and2fokqess5tojy2u	41	30	such	such	JJ
work_dbbvwgi6and2fokqess5tojy2u	41	31	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	41	32	centrosome	centrosome	NN
work_dbbvwgi6and2fokqess5tojy2u	41	33	architecture	architecture	NN
work_dbbvwgi6and2fokqess5tojy2u	41	34	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	41	35	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	41	36	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	41	37	adrenergic	adrenergic	NNP
work_dbbvwgi6and2fokqess5tojy2u	41	38	receptor	receptor	NN
work_dbbvwgi6and2fokqess5tojy2u	41	39	recycling	recycling	NN
work_dbbvwgi6and2fokqess5tojy2u	41	40	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	41	41	RalB	RalB	NNP
work_dbbvwgi6and2fokqess5tojy2u	41	42	signaling	signal	VBG
work_dbbvwgi6and2fokqess5tojy2u	41	43	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	41	44	cancer	cancer	NN
work_dbbvwgi6and2fokqess5tojy2u	41	45	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	41	46	migration	migration	NN
work_dbbvwgi6and2fokqess5tojy2u	41	47	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	41	48	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	41	49	iron	iron	NN
work_dbbvwgi6and2fokqess5tojy2u	41	50	metabolism	metabolism	NN
work_dbbvwgi6and2fokqess5tojy2u	41	51	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	41	52	24	24	CD
work_dbbvwgi6and2fokqess5tojy2u	41	53	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	41	54	26	26	CD
work_dbbvwgi6and2fokqess5tojy2u	41	55	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	41	56	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	42	1	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	42	2	may	may	MD
work_dbbvwgi6and2fokqess5tojy2u	42	3	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	42	4	interact	interact	VB
work_dbbvwgi6and2fokqess5tojy2u	42	5	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	42	6	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	42	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	42	8	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	42	9	manner	manner	NN
work_dbbvwgi6and2fokqess5tojy2u	42	10	independent	independent	JJ
work_dbbvwgi6and2fokqess5tojy2u	42	11	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	42	12	proteasomal	proteasomal	JJ
work_dbbvwgi6and2fokqess5tojy2u	42	13	degradation	degradation	NN
work_dbbvwgi6and2fokqess5tojy2u	42	14	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	43	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	43	2	tumor	tumor	NN
work_dbbvwgi6and2fokqess5tojy2u	43	3	suppressor	suppressor	NN
work_dbbvwgi6and2fokqess5tojy2u	43	4	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	43	5	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	43	6	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	43	7	transcription	transcription	NN
work_dbbvwgi6and2fokqess5tojy2u	43	8	factor	factor	NN
work_dbbvwgi6and2fokqess5tojy2u	43	9	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	43	10	coordinates	coordinate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	43	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	43	12	cellular	cellular	JJ
work_dbbvwgi6and2fokqess5tojy2u	43	13	response	response	NN
work_dbbvwgi6and2fokqess5tojy2u	43	14	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	43	15	several	several	JJ
work_dbbvwgi6and2fokqess5tojy2u	43	16	kinds	kind	NNS
work_dbbvwgi6and2fokqess5tojy2u	43	17	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	43	18	stress	stress	NN
work_dbbvwgi6and2fokqess5tojy2u	43	19	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	43	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	43	21	regulation	regulation	NN
work_dbbvwgi6and2fokqess5tojy2u	43	22	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	43	23	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	43	24	wide	wide	JJ
work_dbbvwgi6and2fokqess5tojy2u	43	25	range	range	NN
work_dbbvwgi6and2fokqess5tojy2u	43	26	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	43	27	genes	gene	NNS
work_dbbvwgi6and2fokqess5tojy2u	43	28	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	43	29	27	27	CD
work_dbbvwgi6and2fokqess5tojy2u	43	30	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	43	31	28	28	CD
work_dbbvwgi6and2fokqess5tojy2u	43	32	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	43	33	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	44	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	44	2	response	response	NN
work_dbbvwgi6and2fokqess5tojy2u	44	3	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	44	4	stress	stress	NN
work_dbbvwgi6and2fokqess5tojy2u	44	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	44	6	p53	p53	CD
work_dbbvwgi6and2fokqess5tojy2u	44	7	transcriptional	transcriptional	JJ
work_dbbvwgi6and2fokqess5tojy2u	44	8	activation	activation	NN
work_dbbvwgi6and2fokqess5tojy2u	44	9	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	44	10	dependent	dependent	JJ
work_dbbvwgi6and2fokqess5tojy2u	44	11	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	44	12	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	44	13	oligomerization	oligomerization	NN
work_dbbvwgi6and2fokqess5tojy2u	44	14	state	state	NN
work_dbbvwgi6and2fokqess5tojy2u	44	15	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	44	16	29	29	CD
work_dbbvwgi6and2fokqess5tojy2u	44	17	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	44	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	45	1	Thus	thus	RB
work_dbbvwgi6and2fokqess5tojy2u	45	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	45	3	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	45	4	mutations	mutation	NNS
work_dbbvwgi6and2fokqess5tojy2u	45	5	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	45	6	impair	impair	VBP
work_dbbvwgi6and2fokqess5tojy2u	45	7	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	45	8	oligomerization	oligomerization	NN
work_dbbvwgi6and2fokqess5tojy2u	45	9	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	45	10	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	45	11	associated	associate	VBN
work_dbbvwgi6and2fokqess5tojy2u	45	12	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	45	13	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	45	14	rare	rare	JJ
work_dbbvwgi6and2fokqess5tojy2u	45	15	hereditary	hereditary	JJ
work_dbbvwgi6and2fokqess5tojy2u	45	16	cancer	cancer	NN
work_dbbvwgi6and2fokqess5tojy2u	45	17	predisposition	predisposition	NN
work_dbbvwgi6and2fokqess5tojy2u	45	18	disorder	disorder	NN
work_dbbvwgi6and2fokqess5tojy2u	45	19	called	call	VBN
work_dbbvwgi6and2fokqess5tojy2u	45	20	Li	Li	NNP
work_dbbvwgi6and2fokqess5tojy2u	45	21	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	45	22	Fraumeni	Fraumeni	NNP
work_dbbvwgi6and2fokqess5tojy2u	45	23	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	45	24	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	45	25	30	30	CD
work_dbbvwgi6and2fokqess5tojy2u	45	26	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	45	27	31	31	CD
work_dbbvwgi6and2fokqess5tojy2u	45	28	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	45	29	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	46	1	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	46	2	interacts	interact	VBZ
work_dbbvwgi6and2fokqess5tojy2u	46	3	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	46	4	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	46	5	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	46	6	modulates	modulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	46	7	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	46	8	transcriptional	transcriptional	JJ
work_dbbvwgi6and2fokqess5tojy2u	46	9	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	46	10	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	46	11	regulating	regulate	VBG
work_dbbvwgi6and2fokqess5tojy2u	46	12	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	46	13	oligomerization	oligomerization	NN
work_dbbvwgi6and2fokqess5tojy2u	46	14	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	46	15	32	32	CD
work_dbbvwgi6and2fokqess5tojy2u	46	16	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	46	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	47	1	RNA	rna	VB
work_dbbvwgi6and2fokqess5tojy2u	47	2	interference	interference	NN
work_dbbvwgi6and2fokqess5tojy2u	47	3	experiments	experiment	NNS
work_dbbvwgi6and2fokqess5tojy2u	47	4	showed	show	VBD
work_dbbvwgi6and2fokqess5tojy2u	47	5	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	47	6	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	47	7	knock	knock	VB
work_dbbvwgi6and2fokqess5tojy2u	47	8	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	47	9	down	down	RP
work_dbbvwgi6and2fokqess5tojy2u	47	10	inhibited	inhibit	VBN
work_dbbvwgi6and2fokqess5tojy2u	47	11	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	47	12	oligomerization	oligomerization	NN
work_dbbvwgi6and2fokqess5tojy2u	47	13	affecting	affect	VBG
work_dbbvwgi6and2fokqess5tojy2u	47	14	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	47	15	transcriptional	transcriptional	JJ
work_dbbvwgi6and2fokqess5tojy2u	47	16	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	47	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	48	1	Under	under	IN
work_dbbvwgi6and2fokqess5tojy2u	48	2	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	48	3	conditions	condition	NNS
work_dbbvwgi6and2fokqess5tojy2u	48	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	48	5	up	up	IN
work_dbbvwgi6and2fokqess5tojy2u	48	6	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	48	7	regulation	regulation	NN
work_dbbvwgi6and2fokqess5tojy2u	48	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	48	9	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	48	10	growth	growth	NN
work_dbbvwgi6and2fokqess5tojy2u	48	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	48	12	increased	increase	VBN
work_dbbvwgi6and2fokqess5tojy2u	48	13	focus	focus	NN
work_dbbvwgi6and2fokqess5tojy2u	48	14	formation	formation	NN
work_dbbvwgi6and2fokqess5tojy2u	48	15	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	48	16	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	48	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	48	18	suggesting	suggest	VBG
work_dbbvwgi6and2fokqess5tojy2u	48	19	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	48	20	important	important	JJ
work_dbbvwgi6and2fokqess5tojy2u	48	21	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	48	22	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	48	23	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	48	24	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	48	25	proliferation	proliferation	NN
work_dbbvwgi6and2fokqess5tojy2u	48	26	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	48	27	32	32	CD
work_dbbvwgi6and2fokqess5tojy2u	48	28	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	48	29	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	49	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	49	2	agreement	agreement	NN
work_dbbvwgi6and2fokqess5tojy2u	49	3	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	49	4	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	49	5	observations	observation	NNS
work_dbbvwgi6and2fokqess5tojy2u	49	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	49	7	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	49	8	association	association	NN
work_dbbvwgi6and2fokqess5tojy2u	49	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	49	10	frameshift	frameshift	NNP
work_dbbvwgi6and2fokqess5tojy2u	49	11	mutations	mutation	NNS
work_dbbvwgi6and2fokqess5tojy2u	49	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	49	13	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	49	14	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	49	15	gastric	gastric	JJ
work_dbbvwgi6and2fokqess5tojy2u	49	16	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	49	17	colorectal	colorectal	JJ
work_dbbvwgi6and2fokqess5tojy2u	49	18	carcinoma	carcinoma	NN
work_dbbvwgi6and2fokqess5tojy2u	49	19	has	have	VBZ
work_dbbvwgi6and2fokqess5tojy2u	49	20	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	49	21	described	describe	VBN
work_dbbvwgi6and2fokqess5tojy2u	49	22	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	49	23	18	18	CD
work_dbbvwgi6and2fokqess5tojy2u	49	24	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	49	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	50	1	Despite	despite	IN
work_dbbvwgi6and2fokqess5tojy2u	50	2	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	50	3	critical	critical	JJ
work_dbbvwgi6and2fokqess5tojy2u	50	4	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	50	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	50	6	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	50	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	50	8	cellular	cellular	JJ
work_dbbvwgi6and2fokqess5tojy2u	50	9	processes	process	NNS
work_dbbvwgi6and2fokqess5tojy2u	50	10	regulated	regulate	VBN
work_dbbvwgi6and2fokqess5tojy2u	50	11	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	50	12	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	50	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	50	14	little	little	JJ
work_dbbvwgi6and2fokqess5tojy2u	50	15	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	50	16	known	know	VBN
work_dbbvwgi6and2fokqess5tojy2u	50	17	about	about	IN
work_dbbvwgi6and2fokqess5tojy2u	50	18	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	50	19	physiological	physiological	JJ
work_dbbvwgi6and2fokqess5tojy2u	50	20	relevance	relevance	NN
work_dbbvwgi6and2fokqess5tojy2u	50	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	51	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	51	2	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	51	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	51	4	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	51	5	found	find	VBN
work_dbbvwgi6and2fokqess5tojy2u	51	6	among	among	IN
work_dbbvwgi6and2fokqess5tojy2u	51	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	51	8	Old	Old	NNP
work_dbbvwgi6and2fokqess5tojy2u	51	9	Order	Order	NNP
work_dbbvwgi6and2fokqess5tojy2u	51	10	Amish	Amish	NNP
work_dbbvwgi6and2fokqess5tojy2u	51	11	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	51	12	features	feature	NNS
work_dbbvwgi6and2fokqess5tojy2u	51	13	similar	similar	JJ
work_dbbvwgi6and2fokqess5tojy2u	51	14	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	51	15	Angelman	Angelman	NNP
work_dbbvwgi6and2fokqess5tojy2u	51	16	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	51	17	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	51	18	suggests	suggest	VBZ
work_dbbvwgi6and2fokqess5tojy2u	51	19	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	51	20	important	important	JJ
work_dbbvwgi6and2fokqess5tojy2u	51	21	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	51	22	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	51	23	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	51	24	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	51	25	neurodevelopment	neurodevelopment	NNP
work_dbbvwgi6and2fokqess5tojy2u	51	26	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	51	27	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	51	28	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	51	29	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	51	30	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	51	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	52	1	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	52	2	determine	determine	VB
work_dbbvwgi6and2fokqess5tojy2u	52	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	52	4	physiological	physiological	JJ
work_dbbvwgi6and2fokqess5tojy2u	52	5	importance	importance	NN
work_dbbvwgi6and2fokqess5tojy2u	52	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	52	7	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	52	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	52	9	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	52	10	decided	decide	VBD
work_dbbvwgi6and2fokqess5tojy2u	52	11	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	52	12	generate	generate	VB
work_dbbvwgi6and2fokqess5tojy2u	52	13	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	52	14	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	52	15	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	52	16	targeted	targeted	JJ
work_dbbvwgi6and2fokqess5tojy2u	52	17	inactivation	inactivation	NN
work_dbbvwgi6and2fokqess5tojy2u	52	18	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	52	19	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	52	20	Herc2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	52	21	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	52	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	53	1	Oncotarget56085www.impactjournals.com/oncotarget	Oncotarget56085www.impactjournals.com/oncotarget	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	53	2	rEsULts	rEsULts	NNP
work_dbbvwgi6and2fokqess5tojy2u	53	3	characterization	characterization	NN
work_dbbvwgi6and2fokqess5tojy2u	53	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	53	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	53	6	Herc2530	herc2530	CD
work_dbbvwgi6and2fokqess5tojy2u	53	7	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	53	8	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	53	9	study	study	VB
work_dbbvwgi6and2fokqess5tojy2u	53	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	53	11	physiological	physiological	JJ
work_dbbvwgi6and2fokqess5tojy2u	53	12	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	53	13	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	53	14	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	53	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	53	16	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	53	17	generated	generate	VBD
work_dbbvwgi6and2fokqess5tojy2u	53	18	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	53	19	novel	novel	JJ
work_dbbvwgi6and2fokqess5tojy2u	53	20	mutant	mutant	NN
work_dbbvwgi6and2fokqess5tojy2u	53	21	allele	allele	NN
work_dbbvwgi6and2fokqess5tojy2u	53	22	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	53	23	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	53	24	Herc2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	53	25	locus	locus	NN
work_dbbvwgi6and2fokqess5tojy2u	53	26	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	53	27	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	53	28	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	53	29	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	53	30	trapped	trap	VBN
work_dbbvwgi6and2fokqess5tojy2u	53	31	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	53	32	stem	stem	NN
work_dbbvwgi6and2fokqess5tojy2u	53	33	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	53	34	ES	es	NN
work_dbbvwgi6and2fokqess5tojy2u	53	35	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	53	36	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	53	37	line	line	NN
work_dbbvwgi6and2fokqess5tojy2u	53	38	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	53	39	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	53	40	Sanger	Sanger	NNP
work_dbbvwgi6and2fokqess5tojy2u	53	41	Institute	Institute	NNP
work_dbbvwgi6and2fokqess5tojy2u	53	42	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	54	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	54	2	ES	es	NN
work_dbbvwgi6and2fokqess5tojy2u	54	3	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	54	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	54	5	here	here	RB
work_dbbvwgi6and2fokqess5tojy2u	54	6	called	call	VBN
work_dbbvwgi6and2fokqess5tojy2u	54	7	Herc2530	Herc2530	NNP
work_dbbvwgi6and2fokqess5tojy2u	54	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	54	9	contain	contain	VBP
work_dbbvwgi6and2fokqess5tojy2u	54	10	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	54	11	pGT0lxr	pgt0lxr	NN
work_dbbvwgi6and2fokqess5tojy2u	54	12	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	54	13	vector	vector	NN
work_dbbvwgi6and2fokqess5tojy2u	54	14	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	54	15	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	54	16	strong	strong	JJ
work_dbbvwgi6and2fokqess5tojy2u	54	17	splice	splice	NN
work_dbbvwgi6and2fokqess5tojy2u	54	18	acceptor	acceptor	NN
work_dbbvwgi6and2fokqess5tojy2u	54	19	site	site	NN
work_dbbvwgi6and2fokqess5tojy2u	54	20	integrated	integrate	VBN
work_dbbvwgi6and2fokqess5tojy2u	54	21	within	within	IN
work_dbbvwgi6and2fokqess5tojy2u	54	22	intron	intron	NNP
work_dbbvwgi6and2fokqess5tojy2u	54	23	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	54	24	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	54	25	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	54	26	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	54	27	Herc2	Herc2	NNP
work_dbbvwgi6and2fokqess5tojy2u	54	28	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	54	29	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	54	30	which	which	WDT
work_dbbvwgi6and2fokqess5tojy2u	54	31	results	result	VBZ
work_dbbvwgi6and2fokqess5tojy2u	54	32	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	54	33	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	54	34	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	54	35	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	54	36	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	54	37	truncated	truncated	JJ
work_dbbvwgi6and2fokqess5tojy2u	54	38	mRNA	mrna	NN
work_dbbvwgi6and2fokqess5tojy2u	54	39	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	55	1	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	55	2	experiments	experiment	NNS
work_dbbvwgi6and2fokqess5tojy2u	55	3	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	55	4	genomic	genomic	JJ
work_dbbvwgi6and2fokqess5tojy2u	55	5	DNA	dna	NN
work_dbbvwgi6and2fokqess5tojy2u	55	6	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	55	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	55	8	tails	tail	NNS
work_dbbvwgi6and2fokqess5tojy2u	55	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	55	10	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	55	11	generated	generate	VBN
work_dbbvwgi6and2fokqess5tojy2u	55	12	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	55	13	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	55	14	ES	ES	NNP
work_dbbvwgi6and2fokqess5tojy2u	55	15	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	55	16	confirmed	confirm	VBD
work_dbbvwgi6and2fokqess5tojy2u	55	17	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	55	18	integration	integration	NN
work_dbbvwgi6and2fokqess5tojy2u	55	19	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	55	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	55	21	trap	trap	NN
work_dbbvwgi6and2fokqess5tojy2u	55	22	between	between	IN
work_dbbvwgi6and2fokqess5tojy2u	55	23	exon	exon	NNP
work_dbbvwgi6and2fokqess5tojy2u	55	24	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	55	25	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	55	26	3	3	CD
work_dbbvwgi6and2fokqess5tojy2u	55	27	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	55	28	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	55	29	1A	1a	NN
work_dbbvwgi6and2fokqess5tojy2u	55	30	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	55	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	56	1	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	56	2	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	56	3	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	56	4	Generation	generation	NN
work_dbbvwgi6and2fokqess5tojy2u	56	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	56	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	56	7	Herc2530	herc2530	CD
work_dbbvwgi6and2fokqess5tojy2u	56	8	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	56	9	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	57	1	A.	a.	JJ
work_dbbvwgi6and2fokqess5tojy2u	57	2	Schematic	schematic	JJ
work_dbbvwgi6and2fokqess5tojy2u	57	3	representation	representation	NN
work_dbbvwgi6and2fokqess5tojy2u	57	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	57	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	57	6	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	57	7	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	57	8	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	57	9	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	57	10	allele	allele	NNS
work_dbbvwgi6and2fokqess5tojy2u	57	11	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	57	12	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	57	13	+	+	SYM
work_dbbvwgi6and2fokqess5tojy2u	57	14	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	57	15	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	57	16	Herc2530	herc2530	CD
work_dbbvwgi6and2fokqess5tojy2u	57	17	allele	allele	NNS
work_dbbvwgi6and2fokqess5tojy2u	57	18	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	57	19	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	57	20	designed	design	VBN
work_dbbvwgi6and2fokqess5tojy2u	57	21	primers	primer	NNS
work_dbbvwgi6and2fokqess5tojy2u	57	22	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	57	23	identify	identify	VB
work_dbbvwgi6and2fokqess5tojy2u	57	24	both	both	DT
work_dbbvwgi6and2fokqess5tojy2u	57	25	alleles	allele	NNS
work_dbbvwgi6and2fokqess5tojy2u	57	26	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	57	27	left	left	RB
work_dbbvwgi6and2fokqess5tojy2u	57	28	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	57	29	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	58	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	58	2	Herc2530	herc2530	CD
work_dbbvwgi6and2fokqess5tojy2u	58	3	allele	allele	NN
work_dbbvwgi6and2fokqess5tojy2u	58	4	contains	contain	VBZ
work_dbbvwgi6and2fokqess5tojy2u	58	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	58	6	pGT0lxr	pGT0lxr	NNP
work_dbbvwgi6and2fokqess5tojy2u	58	7	vector	vector	NN
work_dbbvwgi6and2fokqess5tojy2u	58	8	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	58	9	expresses	express	VBZ
work_dbbvwgi6and2fokqess5tojy2u	58	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	58	11	fusion	fusion	NN
work_dbbvwgi6and2fokqess5tojy2u	58	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	58	13	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	58	14	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	58	15	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	58	16	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	58	17	neomycin	neomycin	NNP
work_dbbvwgi6and2fokqess5tojy2u	58	18	transferase	transferase	NN
work_dbbvwgi6and2fokqess5tojy2u	58	19	within	within	IN
work_dbbvwgi6and2fokqess5tojy2u	58	20	intron	intron	NNP
work_dbbvwgi6and2fokqess5tojy2u	58	21	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	58	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	59	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	59	2	integration	integration	NN
work_dbbvwgi6and2fokqess5tojy2u	59	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	59	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	59	5	trap	trap	NN
work_dbbvwgi6and2fokqess5tojy2u	59	6	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	59	7	determined	determine	VBN
work_dbbvwgi6and2fokqess5tojy2u	59	8	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	59	9	genotyping	genotype	VBG
work_dbbvwgi6and2fokqess5tojy2u	59	10	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	59	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	59	12	indicated	indicate	VBN
work_dbbvwgi6and2fokqess5tojy2u	59	13	primers	primer	NNS
work_dbbvwgi6and2fokqess5tojy2u	59	14	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	59	15	right	right	RB
work_dbbvwgi6and2fokqess5tojy2u	59	16	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	59	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	59	18	530KO01/530KO04	530ko01/530ko04	CD
work_dbbvwgi6and2fokqess5tojy2u	59	19	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	59	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	59	21	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	59	22	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	59	23	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	59	24	allele	allele	NNS
work_dbbvwgi6and2fokqess5tojy2u	59	25	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	59	26	Gal7	Gal7	NNP
work_dbbvwgi6and2fokqess5tojy2u	59	27	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	59	28	Gal8	Gal8	NNP
work_dbbvwgi6and2fokqess5tojy2u	59	29	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	59	30	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	59	31	530	530	CD
work_dbbvwgi6and2fokqess5tojy2u	59	32	allele	allele	NNS
work_dbbvwgi6and2fokqess5tojy2u	59	33	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	60	1	b.	b.	NNP
work_dbbvwgi6and2fokqess5tojy2u	60	2	Exon	Exon	NNP
work_dbbvwgi6and2fokqess5tojy2u	60	3	structure	structure	NN
work_dbbvwgi6and2fokqess5tojy2u	60	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	60	5	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	60	6	+	+	SYM
work_dbbvwgi6and2fokqess5tojy2u	60	7	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	60	8	Herc2530	Herc2530	NNP
work_dbbvwgi6and2fokqess5tojy2u	60	9	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	60	10	left	left	RB
work_dbbvwgi6and2fokqess5tojy2u	60	11	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	60	12	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	61	1	RT	RT	NNP
work_dbbvwgi6and2fokqess5tojy2u	61	2	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	61	3	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	61	4	experiments	experiment	NNS
work_dbbvwgi6and2fokqess5tojy2u	61	5	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	61	6	mRNA	mRNA	NNP
work_dbbvwgi6and2fokqess5tojy2u	61	7	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	61	8	liver	liver	NN
work_dbbvwgi6and2fokqess5tojy2u	61	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	61	10	spleen	spleen	NN
work_dbbvwgi6and2fokqess5tojy2u	61	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	61	12	kidney	kidney	NN
work_dbbvwgi6and2fokqess5tojy2u	61	13	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	61	14	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	61	15	+	+	SYM
work_dbbvwgi6and2fokqess5tojy2u	61	16	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	61	17	Herc2530	herc2530	CD
work_dbbvwgi6and2fokqess5tojy2u	61	18	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	61	19	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	61	20	performed	perform	VBN
work_dbbvwgi6and2fokqess5tojy2u	61	21	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	61	22	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	61	23	indicated	indicate	VBN
work_dbbvwgi6and2fokqess5tojy2u	61	24	primers	primer	NNS
work_dbbvwgi6and2fokqess5tojy2u	61	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	62	1	c.	c.	NNP
work_dbbvwgi6and2fokqess5tojy2u	62	2	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	62	3	products	product	NNS
work_dbbvwgi6and2fokqess5tojy2u	62	4	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	62	5	B	B	NNP
work_dbbvwgi6and2fokqess5tojy2u	62	6	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	62	7	sequenced	sequence	VBN
work_dbbvwgi6and2fokqess5tojy2u	62	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	63	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	63	2	trap	trap	NN
work_dbbvwgi6and2fokqess5tojy2u	63	3	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	63	4	inserted	insert	VBN
work_dbbvwgi6and2fokqess5tojy2u	63	5	after	after	IN
work_dbbvwgi6and2fokqess5tojy2u	63	6	exon	exon	NNP
work_dbbvwgi6and2fokqess5tojy2u	63	7	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	63	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	63	9	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	63	10	which	which	WDT
work_dbbvwgi6and2fokqess5tojy2u	63	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	63	12	mutant	mutant	JJ
work_dbbvwgi6and2fokqess5tojy2u	63	13	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	63	14	contains	contain	VBZ
work_dbbvwgi6and2fokqess5tojy2u	63	15	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	63	16	first	first	JJ
work_dbbvwgi6and2fokqess5tojy2u	63	17	24	24	CD
work_dbbvwgi6and2fokqess5tojy2u	63	18	amino	amino	JJ
work_dbbvwgi6and2fokqess5tojy2u	63	19	acids	acid	NNS
work_dbbvwgi6and2fokqess5tojy2u	63	20	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	63	21	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	63	22	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	63	23	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	63	24	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	63	25	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	63	26	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	63	27	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	63	28	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	64	1	D.	D.	NNP
work_dbbvwgi6and2fokqess5tojy2u	64	2	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	64	3	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	64	4	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	64	5	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	64	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	64	7	Herc2530	herc2530	CD
work_dbbvwgi6and2fokqess5tojy2u	64	8	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	64	9	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	65	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	65	2	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	65	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	65	4	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	65	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	65	6	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	65	7	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	65	8	determined	determine	VBN
work_dbbvwgi6and2fokqess5tojy2u	65	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	65	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	65	11	testes	testis	NNS
work_dbbvwgi6and2fokqess5tojy2u	65	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	65	13	brain	brain	NN
work_dbbvwgi6and2fokqess5tojy2u	65	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	65	15	heart	heart	NN
work_dbbvwgi6and2fokqess5tojy2u	65	16	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	65	17	kidney	kidney	NN
work_dbbvwgi6and2fokqess5tojy2u	65	18	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	65	19	Herc2530	herc2530	CD
work_dbbvwgi6and2fokqess5tojy2u	65	20	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	65	21	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	65	22	detected	detect	VBN
work_dbbvwgi6and2fokqess5tojy2u	65	23	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	65	24	X	x	NN
work_dbbvwgi6and2fokqess5tojy2u	65	25	-	-	NN
work_dbbvwgi6and2fokqess5tojy2u	65	26	gal	gal	NNP
work_dbbvwgi6and2fokqess5tojy2u	65	27	staining	staining	NN
work_dbbvwgi6and2fokqess5tojy2u	65	28	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	66	1	E.	E.	NNP
work_dbbvwgi6and2fokqess5tojy2u	66	2	Scheme	Scheme	NNP
work_dbbvwgi6and2fokqess5tojy2u	66	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	66	4	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	66	5	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	66	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	66	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	66	8	expected	expect	VBN
work_dbbvwgi6and2fokqess5tojy2u	66	9	product	product	NN
work_dbbvwgi6and2fokqess5tojy2u	66	10	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	66	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	66	12	Herc2530	herc2530	CD
work_dbbvwgi6and2fokqess5tojy2u	66	13	allele	allele	NNS
work_dbbvwgi6and2fokqess5tojy2u	66	14	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	67	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	67	2	P594L	P594L	NNP
work_dbbvwgi6and2fokqess5tojy2u	67	3	pathological	pathological	JJ
work_dbbvwgi6and2fokqess5tojy2u	67	4	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	67	5	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	67	6	indicated	indicate	VBN
work_dbbvwgi6and2fokqess5tojy2u	67	7	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	67	8	*	*	NFP
work_dbbvwgi6and2fokqess5tojy2u	67	9	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	67	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	68	1	RLD	rld	NN
work_dbbvwgi6and2fokqess5tojy2u	68	2	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	68	3	RCC1-like	rcc1-like	JJ
work_dbbvwgi6and2fokqess5tojy2u	68	4	domain	domain	NN
work_dbbvwgi6and2fokqess5tojy2u	68	5	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	69	1	Oncotarget56086www.impactjournals.com/oncotarget	Oncotarget56086www.impactjournals.com/oncotarget	NFP
work_dbbvwgi6and2fokqess5tojy2u	69	2	RT	RT	NNP
work_dbbvwgi6and2fokqess5tojy2u	69	3	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	69	4	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	69	5	experiments	experiment	NNS
work_dbbvwgi6and2fokqess5tojy2u	69	6	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	69	7	mRNA	mrna	NN
work_dbbvwgi6and2fokqess5tojy2u	69	8	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	69	9	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	69	10	tissues	tissue	NNS
work_dbbvwgi6and2fokqess5tojy2u	69	11	showed	show	VBD
work_dbbvwgi6and2fokqess5tojy2u	69	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	69	13	formation	formation	NN
work_dbbvwgi6and2fokqess5tojy2u	69	14	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	69	15	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	69	16	truncated	truncated	JJ
work_dbbvwgi6and2fokqess5tojy2u	69	17	mRNA	mrna	NN
work_dbbvwgi6and2fokqess5tojy2u	69	18	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	69	19	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	69	20	fused	fuse	VBN
work_dbbvwgi6and2fokqess5tojy2u	69	21	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	69	22	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	69	23	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	69	24	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	69	25	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	69	26	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	69	27	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	69	28	geo	geo	NNP
work_dbbvwgi6and2fokqess5tojy2u	69	29	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	69	30	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	69	31	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	69	32	1B	1b	NN
work_dbbvwgi6and2fokqess5tojy2u	69	33	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	69	34	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	70	1	Sequencing	sequence	VBG
work_dbbvwgi6and2fokqess5tojy2u	70	2	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	70	3	confirmed	confirm	VBD
work_dbbvwgi6and2fokqess5tojy2u	70	4	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	70	5	results	result	NNS
work_dbbvwgi6and2fokqess5tojy2u	70	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	70	7	revealed	reveal	VBD
work_dbbvwgi6and2fokqess5tojy2u	70	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	70	9	fusion	fusion	NN
work_dbbvwgi6and2fokqess5tojy2u	70	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	70	11	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	70	12	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	70	13	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	70	14	after	after	IN
work_dbbvwgi6and2fokqess5tojy2u	70	15	amino	amino	JJ
work_dbbvwgi6and2fokqess5tojy2u	70	16	acid	acid	NNP
work_dbbvwgi6and2fokqess5tojy2u	70	17	residue	residue	NNP
work_dbbvwgi6and2fokqess5tojy2u	70	18	24	24	CD
work_dbbvwgi6and2fokqess5tojy2u	70	19	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	70	20	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	70	21	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	70	22	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	70	23	1C	1c	NN
work_dbbvwgi6and2fokqess5tojy2u	70	24	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	70	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	71	1	β	β	LS
work_dbbvwgi6and2fokqess5tojy2u	71	2	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	71	3	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	71	4	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	71	5	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	71	6	determined	determine	VBN
work_dbbvwgi6and2fokqess5tojy2u	71	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	71	8	several	several	JJ
work_dbbvwgi6and2fokqess5tojy2u	71	9	tissues	tissue	NNS
work_dbbvwgi6and2fokqess5tojy2u	71	10	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	71	11	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	71	12	1D	1D	NNP
work_dbbvwgi6and2fokqess5tojy2u	71	13	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	71	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	71	15	confirming	confirm	VBG
work_dbbvwgi6and2fokqess5tojy2u	71	16	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	71	17	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	71	18	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	71	19	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	71	20	fused	fuse	VBN
work_dbbvwgi6and2fokqess5tojy2u	71	21	transcript	transcript	NN
work_dbbvwgi6and2fokqess5tojy2u	71	22	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	71	23	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	71	24	first	first	JJ
work_dbbvwgi6and2fokqess5tojy2u	71	25	24	24	CD
work_dbbvwgi6and2fokqess5tojy2u	71	26	amino	amino	NN
work_dbbvwgi6and2fokqess5tojy2u	71	27	acid	acid	NN
work_dbbvwgi6and2fokqess5tojy2u	71	28	residues	residue	NNS
work_dbbvwgi6and2fokqess5tojy2u	71	29	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	71	30	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	71	31	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	71	32	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	71	33	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	71	34	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	71	35	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	72	1	Because	because	IN
work_dbbvwgi6and2fokqess5tojy2u	72	2	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	72	3	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	72	4	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	72	5	has	have	VBZ
work_dbbvwgi6and2fokqess5tojy2u	72	6	4,836	4,836	CD
work_dbbvwgi6and2fokqess5tojy2u	72	7	amino	amino	NN
work_dbbvwgi6and2fokqess5tojy2u	72	8	acid	acid	NN
work_dbbvwgi6and2fokqess5tojy2u	72	9	residues	residue	NNS
work_dbbvwgi6and2fokqess5tojy2u	72	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	72	11	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	72	12	can	can	MD
work_dbbvwgi6and2fokqess5tojy2u	72	13	consider	consider	VB
work_dbbvwgi6and2fokqess5tojy2u	72	14	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	72	15	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	72	16	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	72	17	new	new	NNP
work_dbbvwgi6and2fokqess5tojy2u	72	18	mutant	mutant	NNP
work_dbbvwgi6and2fokqess5tojy2u	72	19	allele	allele	NNP
work_dbbvwgi6and2fokqess5tojy2u	72	20	Herc2530	Herc2530	NNP
work_dbbvwgi6and2fokqess5tojy2u	72	21	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	72	22	functionally	functionally	RB
work_dbbvwgi6and2fokqess5tojy2u	72	23	deleted	delete	VBN
work_dbbvwgi6and2fokqess5tojy2u	72	24	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	72	25	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	72	26	1E	1e	NN
work_dbbvwgi6and2fokqess5tojy2u	72	27	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	72	28	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	73	1	Herc2	Herc2	NNP
work_dbbvwgi6and2fokqess5tojy2u	73	2	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	73	3	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	73	4	essential	essential	JJ
work_dbbvwgi6and2fokqess5tojy2u	73	5	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	73	6	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	73	7	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	73	8	development	development	NNP
work_dbbvwgi6and2fokqess5tojy2u	73	9	91	91	CD
work_dbbvwgi6and2fokqess5tojy2u	73	10	offspring	offspring	NN
work_dbbvwgi6and2fokqess5tojy2u	73	11	born	bear	VBN
work_dbbvwgi6and2fokqess5tojy2u	73	12	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	73	13	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	73	14	intercross	intercross	JJ
work_dbbvwgi6and2fokqess5tojy2u	73	15	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	73	16	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	73	17	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	73	18	genotyped	genotype	VBN
work_dbbvwgi6and2fokqess5tojy2u	73	19	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	73	20	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	73	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	74	1	Among	among	IN
work_dbbvwgi6and2fokqess5tojy2u	74	2	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	74	3	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	74	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	74	5	34	34	CD
work_dbbvwgi6and2fokqess5tojy2u	74	6	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	74	7	37	37	CD
work_dbbvwgi6and2fokqess5tojy2u	74	8	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	74	9	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	74	10	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	74	11	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	74	12	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	74	13	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	74	14	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	74	15	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	74	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	74	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	74	18	57	57	CD
work_dbbvwgi6and2fokqess5tojy2u	74	19	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	74	20	63	63	CD
work_dbbvwgi6and2fokqess5tojy2u	74	21	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	74	22	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	74	23	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	74	24	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	74	25	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	74	26	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	74	27	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	74	28	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	74	29	2A	2a	NN
work_dbbvwgi6and2fokqess5tojy2u	74	30	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	74	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	75	1	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	75	2	could	could	MD
work_dbbvwgi6and2fokqess5tojy2u	75	3	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	75	4	Figure	figure	VB
work_dbbvwgi6and2fokqess5tojy2u	75	5	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	75	6	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	75	7	Analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	75	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	75	9	progeny	progeny	NN
work_dbbvwgi6and2fokqess5tojy2u	75	10	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	75	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	75	12	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	75	13	cross	cross	NN
work_dbbvwgi6and2fokqess5tojy2u	75	14	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	76	1	A.	A.	NNP
work_dbbvwgi6and2fokqess5tojy2u	77	1	Analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	77	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	77	3	offspring	offspring	NN
work_dbbvwgi6and2fokqess5tojy2u	77	4	born	bear	VBN
work_dbbvwgi6and2fokqess5tojy2u	77	5	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	77	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	77	7	intercross	intercross	NN
work_dbbvwgi6and2fokqess5tojy2u	77	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	77	9	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	77	10	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	77	11	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	78	1	Ninety	ninety	CD
work_dbbvwgi6and2fokqess5tojy2u	78	2	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	78	3	one	one	CD
work_dbbvwgi6and2fokqess5tojy2u	78	4	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	78	5	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	78	6	genotyped	genotype	VBN
work_dbbvwgi6and2fokqess5tojy2u	78	7	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	78	8	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	78	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	78	10	genomic	genomic	JJ
work_dbbvwgi6and2fokqess5tojy2u	78	11	DNA	DNA	NNP
work_dbbvwgi6and2fokqess5tojy2u	78	12	isolated	isolate	VBN
work_dbbvwgi6and2fokqess5tojy2u	78	13	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	78	14	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	78	15	tails	tail	NNS
work_dbbvwgi6and2fokqess5tojy2u	78	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	79	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	79	2	expected	expect	VBN
work_dbbvwgi6and2fokqess5tojy2u	79	3	frequencies	frequency	NNS
work_dbbvwgi6and2fokqess5tojy2u	79	4	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	79	5	Herc2+/+	Herc2+/+	NNP
work_dbbvwgi6and2fokqess5tojy2u	79	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	79	7	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	79	8	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	79	9	obtained	obtain	VBN
work_dbbvwgi6and2fokqess5tojy2u	79	10	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	79	11	however	however	RB
work_dbbvwgi6and2fokqess5tojy2u	79	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	79	13	no	no	DT
work_dbbvwgi6and2fokqess5tojy2u	79	14	homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	79	15	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	79	16	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	79	17	Herc2530/530	Herc2530/530	NFP
work_dbbvwgi6and2fokqess5tojy2u	79	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	79	19	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	79	20	identified	identify	VBN
work_dbbvwgi6and2fokqess5tojy2u	79	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	80	1	b.	b.	NNP
work_dbbvwgi6and2fokqess5tojy2u	81	1	Analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	81	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	81	3	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	81	4	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	81	5	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	81	6	Herc2530/530	herc2530/530	CD
work_dbbvwgi6and2fokqess5tojy2u	81	7	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	81	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	82	1	Embryos	embryo	NNS
work_dbbvwgi6and2fokqess5tojy2u	82	2	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	82	3	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	82	4	pregnant	pregnant	JJ
work_dbbvwgi6and2fokqess5tojy2u	82	5	females	female	NNS
work_dbbvwgi6and2fokqess5tojy2u	82	6	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	82	7	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	82	8	stages	stage	NNS
work_dbbvwgi6and2fokqess5tojy2u	82	9	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	82	10	isolated	isolate	VBN
work_dbbvwgi6and2fokqess5tojy2u	82	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	82	12	genotyped	genotype	VBN
work_dbbvwgi6and2fokqess5tojy2u	82	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	83	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	83	2	Herc2+/+	herc2+/+	NN
work_dbbvwgi6and2fokqess5tojy2u	83	3	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	83	4	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	83	5	genotypes	genotype	NNS
work_dbbvwgi6and2fokqess5tojy2u	83	6	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	83	7	identified	identify	VBN
work_dbbvwgi6and2fokqess5tojy2u	83	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	83	9	but	but	CC
work_dbbvwgi6and2fokqess5tojy2u	83	10	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	83	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	83	12	Herc2530/530	herc2530/530	CD
work_dbbvwgi6and2fokqess5tojy2u	83	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	84	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	84	2	placentas	placenta	NNS
work_dbbvwgi6and2fokqess5tojy2u	84	3	without	without	IN
work_dbbvwgi6and2fokqess5tojy2u	84	4	embryos	embryo	NNS
work_dbbvwgi6and2fokqess5tojy2u	84	5	could	could	MD
work_dbbvwgi6and2fokqess5tojy2u	84	6	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	84	7	be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	84	8	genotyped	genotype	VBN
work_dbbvwgi6and2fokqess5tojy2u	84	9	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	85	1	c.	c.	NNP
work_dbbvwgi6and2fokqess5tojy2u	85	2	Analysis	Analysis	NNP
work_dbbvwgi6and2fokqess5tojy2u	85	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	85	4	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	85	5	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	85	6	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	85	7	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	85	8	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	85	9	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	86	1	Lysates	lysate	NNS
work_dbbvwgi6and2fokqess5tojy2u	86	2	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	86	3	brains	brain	NNS
work_dbbvwgi6and2fokqess5tojy2u	86	4	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	86	5	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	86	6	stages	stage	NNS
work_dbbvwgi6and2fokqess5tojy2u	86	7	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	86	8	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	86	9	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	86	10	immunoblotting	immunoblotte	VBG
work_dbbvwgi6and2fokqess5tojy2u	86	11	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	86	12	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	86	13	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	86	14	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	86	15	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	86	16	actin	actin	NNP
work_dbbvwgi6and2fokqess5tojy2u	86	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	87	1	E16	E16	NNP
work_dbbvwgi6and2fokqess5tojy2u	87	2	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	87	3	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	87	4	day	day	NN
work_dbbvwgi6and2fokqess5tojy2u	87	5	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	87	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	87	7	P0	p0	NN
work_dbbvwgi6and2fokqess5tojy2u	87	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	87	9	P5	p5	NN
work_dbbvwgi6and2fokqess5tojy2u	87	10	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	87	11	P15	P15	NNP
work_dbbvwgi6and2fokqess5tojy2u	87	12	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	87	13	post	post	JJ
work_dbbvwgi6and2fokqess5tojy2u	87	14	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	87	15	natal	natal	JJ
work_dbbvwgi6and2fokqess5tojy2u	87	16	day	day	NN
work_dbbvwgi6and2fokqess5tojy2u	87	17	0	0	CD
work_dbbvwgi6and2fokqess5tojy2u	87	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	87	19	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	87	20	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	87	21	15	15	CD
work_dbbvwgi6and2fokqess5tojy2u	87	22	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	87	23	respectively	respectively	RB
work_dbbvwgi6and2fokqess5tojy2u	87	24	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	87	25	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	87	26	AD	ad	NN
work_dbbvwgi6and2fokqess5tojy2u	87	27	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	87	28	adult	adult	NN
work_dbbvwgi6and2fokqess5tojy2u	87	29	animal	animal	NN
work_dbbvwgi6and2fokqess5tojy2u	87	30	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	87	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	88	1	Oncotarget56087www.impactjournals.com/oncotarget	oncotarget56087www.impactjournals.com/oncotarget	ADD
work_dbbvwgi6and2fokqess5tojy2u	88	2	identify	identify	VB
work_dbbvwgi6and2fokqess5tojy2u	88	3	any	any	DT
work_dbbvwgi6and2fokqess5tojy2u	88	4	viable	viable	JJ
work_dbbvwgi6and2fokqess5tojy2u	88	5	homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	88	6	Herc2530/530	herc2530/530	ADD
work_dbbvwgi6and2fokqess5tojy2u	88	7	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	89	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	89	2	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	89	3	suggested	suggest	VBD
work_dbbvwgi6and2fokqess5tojy2u	89	4	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	89	5	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	89	6	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	89	7	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	89	8	null	null	JJ
work_dbbvwgi6and2fokqess5tojy2u	89	9	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	89	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	90	1	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	90	2	determine	determine	VB
work_dbbvwgi6and2fokqess5tojy2u	90	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	90	4	time	time	NN
work_dbbvwgi6and2fokqess5tojy2u	90	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	90	6	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	90	7	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	90	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	90	9	Herc2530/530	herc2530/530	CD
work_dbbvwgi6and2fokqess5tojy2u	90	10	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	90	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	90	12	genomic	genomic	JJ
work_dbbvwgi6and2fokqess5tojy2u	90	13	DNA	DNA	NNP
work_dbbvwgi6and2fokqess5tojy2u	90	14	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	90	15	isolated	isolate	VBN
work_dbbvwgi6and2fokqess5tojy2u	90	16	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	90	17	embryos	embryo	NNS
work_dbbvwgi6and2fokqess5tojy2u	90	18	harvested	harvest	VBN
work_dbbvwgi6and2fokqess5tojy2u	90	19	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	90	20	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	90	21	stages	stage	NNS
work_dbbvwgi6and2fokqess5tojy2u	90	22	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	90	23	E7.5	e7.5	NN
work_dbbvwgi6and2fokqess5tojy2u	90	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	90	25	E8.5	E8.5	NNP
work_dbbvwgi6and2fokqess5tojy2u	90	26	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	90	27	E10.5	E10.5	NNP
work_dbbvwgi6and2fokqess5tojy2u	90	28	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	90	29	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	90	30	pregnancy	pregnancy	NN
work_dbbvwgi6and2fokqess5tojy2u	90	31	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	90	32	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	90	33	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	90	34	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	91	1	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	91	2	isolated	isolate	VBD
work_dbbvwgi6and2fokqess5tojy2u	91	3	34	34	CD
work_dbbvwgi6and2fokqess5tojy2u	91	4	placentas	placenta	NNS
work_dbbvwgi6and2fokqess5tojy2u	91	5	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	91	6	observed	observe	VBD
work_dbbvwgi6and2fokqess5tojy2u	91	7	14	14	CD
work_dbbvwgi6and2fokqess5tojy2u	91	8	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	91	9	41	41	CD
work_dbbvwgi6and2fokqess5tojy2u	91	10	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	91	11	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	91	12	without	without	IN
work_dbbvwgi6and2fokqess5tojy2u	91	13	embryos	embryo	NNS
work_dbbvwgi6and2fokqess5tojy2u	91	14	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	91	15	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	91	16	2B	2B	NNS
work_dbbvwgi6and2fokqess5tojy2u	91	17	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	91	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	92	1	Among	among	IN
work_dbbvwgi6and2fokqess5tojy2u	92	2	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	92	3	embryos	embryo	NNS
work_dbbvwgi6and2fokqess5tojy2u	92	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	92	5	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	92	6	identified	identify	VBD
work_dbbvwgi6and2fokqess5tojy2u	92	7	both	both	DT
work_dbbvwgi6and2fokqess5tojy2u	92	8	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	92	9	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	92	10	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	92	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	92	12	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	92	13	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	92	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	92	15	but	but	CC
work_dbbvwgi6and2fokqess5tojy2u	92	16	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	92	17	homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	92	18	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	92	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	93	1	At	at	IN
work_dbbvwgi6and2fokqess5tojy2u	93	2	day	day	NN
work_dbbvwgi6and2fokqess5tojy2u	93	3	7.5	7.5	CD
work_dbbvwgi6and2fokqess5tojy2u	93	4	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	93	5	8.5	8.5	CD
work_dbbvwgi6and2fokqess5tojy2u	93	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	93	7	placentas	placenta	NNS
work_dbbvwgi6and2fokqess5tojy2u	93	8	without	without	IN
work_dbbvwgi6and2fokqess5tojy2u	93	9	embryos	embryo	NNS
work_dbbvwgi6and2fokqess5tojy2u	93	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	93	11	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	93	12	observed	observe	VBD
work_dbbvwgi6and2fokqess5tojy2u	93	13	some	some	DT
work_dbbvwgi6and2fokqess5tojy2u	93	14	residuals	residual	NNS
work_dbbvwgi6and2fokqess5tojy2u	93	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	94	1	At	at	IN
work_dbbvwgi6and2fokqess5tojy2u	94	2	day	day	NN
work_dbbvwgi6and2fokqess5tojy2u	94	3	10.5	10.5	CD
work_dbbvwgi6and2fokqess5tojy2u	94	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	94	5	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	94	6	residuals	residual	NNS
work_dbbvwgi6and2fokqess5tojy2u	94	7	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	94	8	completely	completely	RB
work_dbbvwgi6and2fokqess5tojy2u	94	9	resorbed	resorb	VBN
work_dbbvwgi6and2fokqess5tojy2u	94	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	95	1	Most	most	RBS
work_dbbvwgi6and2fokqess5tojy2u	95	2	likely	likely	RB
work_dbbvwgi6and2fokqess5tojy2u	95	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	95	4	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	95	5	residuals	residual	NNS
work_dbbvwgi6and2fokqess5tojy2u	95	6	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	95	7	rests	rest	NNS
work_dbbvwgi6and2fokqess5tojy2u	95	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	95	9	embryos	embryo	NNS
work_dbbvwgi6and2fokqess5tojy2u	95	10	homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	95	11	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	95	12	Herc2530	herc2530	CD
work_dbbvwgi6and2fokqess5tojy2u	95	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	96	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	96	2	results	result	NNS
work_dbbvwgi6and2fokqess5tojy2u	96	3	indicate	indicate	VBP
work_dbbvwgi6and2fokqess5tojy2u	96	4	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	96	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	96	6	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	96	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	96	8	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	96	9	least	least	JJS
work_dbbvwgi6and2fokqess5tojy2u	96	10	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	96	11	normal	normal	JJ
work_dbbvwgi6and2fokqess5tojy2u	96	12	Herc2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	96	13	copy	copy	NN
work_dbbvwgi6and2fokqess5tojy2u	96	14	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	96	15	essential	essential	JJ
work_dbbvwgi6and2fokqess5tojy2u	96	16	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	96	17	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	96	18	completion	completion	NN
work_dbbvwgi6and2fokqess5tojy2u	96	19	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	96	20	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	96	21	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	96	22	before	before	IN
work_dbbvwgi6and2fokqess5tojy2u	96	23	day	day	NN
work_dbbvwgi6and2fokqess5tojy2u	96	24	7.5	7.5	CD
work_dbbvwgi6and2fokqess5tojy2u	96	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	97	1	Genes	gene	NNS
work_dbbvwgi6and2fokqess5tojy2u	97	2	important	important	JJ
work_dbbvwgi6and2fokqess5tojy2u	97	3	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	97	4	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	97	5	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	97	6	usually	usually	RB
work_dbbvwgi6and2fokqess5tojy2u	97	7	highly	highly	RB
work_dbbvwgi6and2fokqess5tojy2u	97	8	expressed	express	VBN
work_dbbvwgi6and2fokqess5tojy2u	97	9	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	97	10	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	97	11	stages	stage	NNS
work_dbbvwgi6and2fokqess5tojy2u	97	12	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	98	1	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	98	2	determine	determine	VB
work_dbbvwgi6and2fokqess5tojy2u	98	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	98	4	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	98	5	pattern	pattern	NN
work_dbbvwgi6and2fokqess5tojy2u	98	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	98	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	98	8	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	98	9	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	98	10	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	98	11	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	98	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	98	13	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	98	14	analyzed	analyze	VBD
work_dbbvwgi6and2fokqess5tojy2u	98	15	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	98	16	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	98	17	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	98	18	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	98	19	endogenous	endogenous	JJ
work_dbbvwgi6and2fokqess5tojy2u	98	20	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	98	21	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	98	22	samples	sample	NNS
work_dbbvwgi6and2fokqess5tojy2u	98	23	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	98	24	brains	brain	NNS
work_dbbvwgi6and2fokqess5tojy2u	98	25	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	98	26	embryonic	embryonic	NNP
work_dbbvwgi6and2fokqess5tojy2u	98	27	day	day	NN
work_dbbvwgi6and2fokqess5tojy2u	98	28	E16	E16	NNP
work_dbbvwgi6and2fokqess5tojy2u	98	29	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	98	30	postnatal	postnatal	JJ
work_dbbvwgi6and2fokqess5tojy2u	98	31	days	day	NNS
work_dbbvwgi6and2fokqess5tojy2u	98	32	P1	p1	NN
work_dbbvwgi6and2fokqess5tojy2u	98	33	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	98	34	P5	P5	NNP
work_dbbvwgi6and2fokqess5tojy2u	98	35	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	98	36	P15	P15	NNP
work_dbbvwgi6and2fokqess5tojy2u	98	37	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	98	38	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	98	39	adult	adult	NN
work_dbbvwgi6and2fokqess5tojy2u	98	40	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	98	41	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	98	42	8	8	CD
work_dbbvwgi6and2fokqess5tojy2u	98	43	weeks	week	NNS
work_dbbvwgi6and2fokqess5tojy2u	98	44	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	98	45	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	99	1	Anti	Anti	NNP
work_dbbvwgi6and2fokqess5tojy2u	99	2	-	-	NNP
work_dbbvwgi6and2fokqess5tojy2u	99	3	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	99	4	antibodies	antibody	NNS
work_dbbvwgi6and2fokqess5tojy2u	99	5	detected	detect	VBD
work_dbbvwgi6and2fokqess5tojy2u	99	6	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	99	7	double	double	JJ
work_dbbvwgi6and2fokqess5tojy2u	99	8	band	band	NN
work_dbbvwgi6and2fokqess5tojy2u	99	9	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	99	10	decreased	decrease	VBD
work_dbbvwgi6and2fokqess5tojy2u	99	11	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	99	12	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	99	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	99	14	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	99	15	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	99	16	highest	high	JJS
work_dbbvwgi6and2fokqess5tojy2u	99	17	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	99	18	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	99	19	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	99	20	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	99	21	stage	stage	NN
work_dbbvwgi6and2fokqess5tojy2u	99	22	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	99	23	lower	low	JJR
work_dbbvwgi6and2fokqess5tojy2u	99	24	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	99	25	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	99	26	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	99	27	adult	adult	NN
work_dbbvwgi6and2fokqess5tojy2u	99	28	animal	animal	NN
work_dbbvwgi6and2fokqess5tojy2u	99	29	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	99	30	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	99	31	2C	2c	NN
work_dbbvwgi6and2fokqess5tojy2u	99	32	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	99	33	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	100	1	Similar	similar	JJ
work_dbbvwgi6and2fokqess5tojy2u	100	2	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	100	3	profiles	profile	NNS
work_dbbvwgi6and2fokqess5tojy2u	100	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	100	5	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	100	6	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	100	7	other	other	JJ
work_dbbvwgi6and2fokqess5tojy2u	100	8	members	member	NNS
work_dbbvwgi6and2fokqess5tojy2u	100	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	100	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	100	11	HERC	HERC	NNP
work_dbbvwgi6and2fokqess5tojy2u	100	12	family	family	NN
work_dbbvwgi6and2fokqess5tojy2u	100	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	100	14	such	such	JJ
work_dbbvwgi6and2fokqess5tojy2u	100	15	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	100	16	HERC1	HERC1	NNS
work_dbbvwgi6and2fokqess5tojy2u	100	17	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	100	18	HERC3	HERC3	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	100	19	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	100	20	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	100	21	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	100	22	shown	show	VBN
work_dbbvwgi6and2fokqess5tojy2u	100	23	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	100	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	100	25	suggesting	suggest	VBG
work_dbbvwgi6and2fokqess5tojy2u	100	26	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	100	27	important	important	JJ
work_dbbvwgi6and2fokqess5tojy2u	100	28	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	100	29	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	100	30	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	100	31	HERC	HERC	NNP
work_dbbvwgi6and2fokqess5tojy2u	100	32	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	100	33	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	100	34	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	100	35	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	100	36	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	101	1	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	101	2	inactivation	inactivation	NN
work_dbbvwgi6and2fokqess5tojy2u	101	3	did	do	VBD
work_dbbvwgi6and2fokqess5tojy2u	101	4	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	101	5	rescue	rescue	VB
work_dbbvwgi6and2fokqess5tojy2u	101	6	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	101	7	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	101	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	101	9	homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	101	10	Herc2530	herc2530	CD
work_dbbvwgi6and2fokqess5tojy2u	101	11	mice	mice	NN
work_dbbvwgi6and2fokqess5tojy2u	101	12	Growth	growth	NN
work_dbbvwgi6and2fokqess5tojy2u	101	13	curves	curve	NNS
work_dbbvwgi6and2fokqess5tojy2u	101	14	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	101	15	survival	survival	NN
work_dbbvwgi6and2fokqess5tojy2u	101	16	rates	rate	NNS
work_dbbvwgi6and2fokqess5tojy2u	101	17	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	101	18	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	101	19	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	101	20	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	101	21	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	101	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	102	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	102	2	growth	growth	NN
work_dbbvwgi6and2fokqess5tojy2u	102	3	curve	curve	NN
work_dbbvwgi6and2fokqess5tojy2u	102	4	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	102	5	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	102	6	significantly	significantly	RB
work_dbbvwgi6and2fokqess5tojy2u	102	7	altered	alter	VBN
work_dbbvwgi6and2fokqess5tojy2u	102	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	102	9	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	102	10	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	102	11	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	102	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	102	13	time	time	NN
work_dbbvwgi6and2fokqess5tojy2u	102	14	studied	study	VBN
work_dbbvwgi6and2fokqess5tojy2u	102	15	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	102	16	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	102	17	3A	3a	NN
work_dbbvwgi6and2fokqess5tojy2u	102	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	102	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	103	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	103	2	survival	survival	NN
work_dbbvwgi6and2fokqess5tojy2u	103	3	rate	rate	NN
work_dbbvwgi6and2fokqess5tojy2u	103	4	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	103	5	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	103	6	similar	similar	JJ
work_dbbvwgi6and2fokqess5tojy2u	103	7	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	103	8	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	103	9	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	103	10	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	103	11	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	103	12	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	103	13	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	103	14	period	period	NN
work_dbbvwgi6and2fokqess5tojy2u	103	15	studied	study	VBN
work_dbbvwgi6and2fokqess5tojy2u	103	16	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	103	17	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	103	18	3B	3b	NN
work_dbbvwgi6and2fokqess5tojy2u	103	19	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	103	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	104	1	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	104	2	3	3	CD
work_dbbvwgi6and2fokqess5tojy2u	104	3	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	104	4	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	104	5	inactivation	inactivation	NN
work_dbbvwgi6and2fokqess5tojy2u	104	6	did	do	VBD
work_dbbvwgi6and2fokqess5tojy2u	104	7	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	104	8	rescue	rescue	VB
work_dbbvwgi6and2fokqess5tojy2u	104	9	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	104	10	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	104	11	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	104	12	Herc2530/530	Herc2530/530	``
work_dbbvwgi6and2fokqess5tojy2u	104	13	homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	104	14	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	104	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	105	1	Graphs	graph	NNS
work_dbbvwgi6and2fokqess5tojy2u	105	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	105	3	growth	growth	NN
work_dbbvwgi6and2fokqess5tojy2u	105	4	rate	rate	NN
work_dbbvwgi6and2fokqess5tojy2u	105	5	A.	a.	NN
work_dbbvwgi6and2fokqess5tojy2u	105	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	105	7	survival	survival	NNP
work_dbbvwgi6and2fokqess5tojy2u	105	8	b.	b.	NNP
work_dbbvwgi6and2fokqess5tojy2u	105	9	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	105	10	Herc2+/+	Herc2+/+	NNP
work_dbbvwgi6and2fokqess5tojy2u	105	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	105	12	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	105	13	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	105	14	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	106	1	Growth	growth	NN
work_dbbvwgi6and2fokqess5tojy2u	106	2	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	106	3	survival	survival	NN
work_dbbvwgi6and2fokqess5tojy2u	106	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	106	5	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	106	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	106	7	male	male	JJ
work_dbbvwgi6and2fokqess5tojy2u	106	8	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	106	9	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	106	10	n>10	n>10	NN
work_dbbvwgi6and2fokqess5tojy2u	106	11	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	106	12	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	106	13	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	106	14	indicated	indicate	VBN
work_dbbvwgi6and2fokqess5tojy2u	106	15	weeks	week	NNS
work_dbbvwgi6and2fokqess5tojy2u	106	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	107	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	107	2	survival	survival	NN
work_dbbvwgi6and2fokqess5tojy2u	107	3	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	107	4	p53-/-	p53-/-	NNP
work_dbbvwgi6and2fokqess5tojy2u	107	5	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	107	6	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	107	7	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	107	8	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	107	9	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	108	1	c.	c.	NN
work_dbbvwgi6and2fokqess5tojy2u	108	2	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	108	3	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	108	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	108	5	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	108	6	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	108	7	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	108	8	cross	cross	NN
work_dbbvwgi6and2fokqess5tojy2u	108	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	108	10	double	double	JJ
work_dbbvwgi6and2fokqess5tojy2u	108	11	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	108	12	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	108	13	p53+/-	p53+/-	JJ
work_dbbvwgi6and2fokqess5tojy2u	108	14	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	108	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	109	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	109	2	offspring	offspring	NN
work_dbbvwgi6and2fokqess5tojy2u	109	3	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	109	4	genotyped	genotype	VBN
work_dbbvwgi6and2fokqess5tojy2u	109	5	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	109	6	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	109	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	109	8	genomic	genomic	JJ
work_dbbvwgi6and2fokqess5tojy2u	109	9	DNA	dna	NN
work_dbbvwgi6and2fokqess5tojy2u	109	10	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	109	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	109	12	appropriate	appropriate	JJ
work_dbbvwgi6and2fokqess5tojy2u	109	13	primers	primer	NNS
work_dbbvwgi6and2fokqess5tojy2u	109	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	109	15	indicating	indicate	VBG
work_dbbvwgi6and2fokqess5tojy2u	109	16	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	109	17	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	109	18	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	109	19	lethal	lethal	JJ
work_dbbvwgi6and2fokqess5tojy2u	109	20	phenotype	phenotype	NN
work_dbbvwgi6and2fokqess5tojy2u	109	21	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	109	22	Herc2530/530	Herc2530/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	109	23	embryos	embryo	NNS
work_dbbvwgi6and2fokqess5tojy2u	109	24	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	109	25	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	109	26	rescued	rescue	VBN
work_dbbvwgi6and2fokqess5tojy2u	109	27	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	109	28	crossing	cross	VBG
work_dbbvwgi6and2fokqess5tojy2u	109	29	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	109	30	p53-/-	p53-/-	NNP
work_dbbvwgi6and2fokqess5tojy2u	109	31	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	109	32	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	110	1	Oncotarget56088www.impactjournals.com/oncotarget	oncotarget56088www.impactjournals.com/oncotarget	ADD
work_dbbvwgi6and2fokqess5tojy2u	110	2	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	110	3	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	110	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	110	5	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	110	6	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	110	7	show	show	VB
work_dbbvwgi6and2fokqess5tojy2u	110	8	reduced	reduce	VBN
work_dbbvwgi6and2fokqess5tojy2u	110	9	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	110	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	110	11	HErc2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	110	12	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	110	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	111	1	A.	a.	JJ
work_dbbvwgi6and2fokqess5tojy2u	111	2	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	111	3	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	111	4	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	111	5	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	111	6	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	111	7	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	111	8	immunoblotting	immunoblotte	VBG
work_dbbvwgi6and2fokqess5tojy2u	111	9	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	111	10	specific	specific	JJ
work_dbbvwgi6and2fokqess5tojy2u	111	11	antibodies	antibody	NNS
work_dbbvwgi6and2fokqess5tojy2u	111	12	against	against	IN
work_dbbvwgi6and2fokqess5tojy2u	111	13	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	111	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	111	15	several	several	JJ
work_dbbvwgi6and2fokqess5tojy2u	111	16	tissues	tissue	NNS
work_dbbvwgi6and2fokqess5tojy2u	111	17	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	111	18	8	8	CD
work_dbbvwgi6and2fokqess5tojy2u	111	19	week	week	NN
work_dbbvwgi6and2fokqess5tojy2u	111	20	old	old	JJ
work_dbbvwgi6and2fokqess5tojy2u	111	21	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	111	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	112	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	112	2	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	112	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	112	4	HERC2	HERC2	NNS
work_dbbvwgi6and2fokqess5tojy2u	112	5	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	112	6	quantified	quantify	VBN
work_dbbvwgi6and2fokqess5tojy2u	112	7	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	112	8	n	n	NN
work_dbbvwgi6and2fokqess5tojy2u	112	9	=	=	SYM
work_dbbvwgi6and2fokqess5tojy2u	112	10	8)	8)	CD
work_dbbvwgi6and2fokqess5tojy2u	112	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	112	12	normalized	normalize	VBD
work_dbbvwgi6and2fokqess5tojy2u	112	13	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	112	14	respect	respect	NN
work_dbbvwgi6and2fokqess5tojy2u	112	15	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	112	16	β	β	NN
work_dbbvwgi6and2fokqess5tojy2u	112	17	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	112	18	actin	actin	NN
work_dbbvwgi6and2fokqess5tojy2u	112	19	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	112	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	113	1	b.	b.	NNP
work_dbbvwgi6and2fokqess5tojy2u	113	2	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	113	3	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	113	4	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	113	5	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	113	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	113	7	brain	brain	NN
work_dbbvwgi6and2fokqess5tojy2u	113	8	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	113	9	Herc2530	herc2530	CD
work_dbbvwgi6and2fokqess5tojy2u	113	10	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	113	11	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	114	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	114	2	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	114	3	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	114	4	galactosidase	galactosidase	NN
work_dbbvwgi6and2fokqess5tojy2u	114	5	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	114	6	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	114	7	detected	detect	VBN
work_dbbvwgi6and2fokqess5tojy2u	114	8	ubiquitously	ubiquitously	RB
work_dbbvwgi6and2fokqess5tojy2u	114	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	114	10	all	all	DT
work_dbbvwgi6and2fokqess5tojy2u	114	11	areas	area	NNS
work_dbbvwgi6and2fokqess5tojy2u	114	12	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	114	13	X	x	NN
work_dbbvwgi6and2fokqess5tojy2u	114	14	-	-	NN
work_dbbvwgi6and2fokqess5tojy2u	114	15	gal	gal	NNP
work_dbbvwgi6and2fokqess5tojy2u	114	16	staining	staining	NN
work_dbbvwgi6and2fokqess5tojy2u	114	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	115	1	However	however	RB
work_dbbvwgi6and2fokqess5tojy2u	115	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	115	3	there	there	EX
work_dbbvwgi6and2fokqess5tojy2u	115	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	115	5	forebrain	forebrain	NNP
work_dbbvwgi6and2fokqess5tojy2u	115	6	cortical	cortical	JJ
work_dbbvwgi6and2fokqess5tojy2u	115	7	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	115	8	subcortical	subcortical	JJ
work_dbbvwgi6and2fokqess5tojy2u	115	9	areas	area	NNS
work_dbbvwgi6and2fokqess5tojy2u	115	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	115	11	which	which	WDT
work_dbbvwgi6and2fokqess5tojy2u	115	12	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	115	13	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	115	14	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	115	15	labeling	labeling	NN
work_dbbvwgi6and2fokqess5tojy2u	115	16	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	115	17	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	115	18	most	most	RBS
work_dbbvwgi6and2fokqess5tojy2u	115	19	intense	intense	JJ
work_dbbvwgi6and2fokqess5tojy2u	115	20	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	115	21	asterisks	asterisks	NNP
work_dbbvwgi6and2fokqess5tojy2u	115	22	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	115	23	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	116	1	c.	c.	NN
work_dbbvwgi6and2fokqess5tojy2u	116	2	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	116	3	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	116	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	116	5	HERC2	HERC2	NNS
work_dbbvwgi6and2fokqess5tojy2u	116	6	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	116	7	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	116	8	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	116	9	immunoblotting	immunoblotte	VBG
work_dbbvwgi6and2fokqess5tojy2u	116	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	116	11	lysates	lysate	NNS
work_dbbvwgi6and2fokqess5tojy2u	116	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	116	13	cerebellum	cerebellum	NN
work_dbbvwgi6and2fokqess5tojy2u	116	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	116	15	cerebral	cerebral	NNP
work_dbbvwgi6and2fokqess5tojy2u	116	16	cortex	cortex	NNP
work_dbbvwgi6and2fokqess5tojy2u	116	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	116	18	diencephalon	diencephalon	NN
work_dbbvwgi6and2fokqess5tojy2u	116	19	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	116	20	Herc2+/+	Herc2+/+	NNP
work_dbbvwgi6and2fokqess5tojy2u	116	21	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	116	22	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	116	23	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	116	24	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	116	25	P4	P4	NNP
work_dbbvwgi6and2fokqess5tojy2u	116	26	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	116	27	post	post	JJ
work_dbbvwgi6and2fokqess5tojy2u	116	28	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	116	29	natal	natal	JJ
work_dbbvwgi6and2fokqess5tojy2u	116	30	day	day	NN
work_dbbvwgi6and2fokqess5tojy2u	116	31	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	116	32	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	116	33	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	117	1	BA	BA	NNP
work_dbbvwgi6and2fokqess5tojy2u	117	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	117	3	basal	basal	NNP
work_dbbvwgi6and2fokqess5tojy2u	117	4	amygdala	amygdala	NNP
work_dbbvwgi6and2fokqess5tojy2u	117	5	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	118	1	CA1	CA1	NNP
work_dbbvwgi6and2fokqess5tojy2u	118	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	118	3	pyramidal	pyramidal	JJ
work_dbbvwgi6and2fokqess5tojy2u	118	4	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	118	5	layer	layer	NN
work_dbbvwgi6and2fokqess5tojy2u	118	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	118	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	118	8	hippocampal	hippocampal	NNP
work_dbbvwgi6and2fokqess5tojy2u	118	9	cornu	cornu	NNP
work_dbbvwgi6and2fokqess5tojy2u	118	10	ammonis	ammonis	NNP
work_dbbvwgi6and2fokqess5tojy2u	118	11	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	118	12	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	119	1	DEn	DEn	NNS
work_dbbvwgi6and2fokqess5tojy2u	119	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	119	3	dorsal	dorsal	NN
work_dbbvwgi6and2fokqess5tojy2u	119	4	endopiriform	endopiriform	NN
work_dbbvwgi6and2fokqess5tojy2u	119	5	nucleus	nucleus	NN
work_dbbvwgi6and2fokqess5tojy2u	119	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	120	1	DG	DG	NNP
work_dbbvwgi6and2fokqess5tojy2u	120	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	120	3	granular	granular	JJ
work_dbbvwgi6and2fokqess5tojy2u	120	4	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	120	5	layer	layer	NN
work_dbbvwgi6and2fokqess5tojy2u	120	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	120	7	hippocampal	hippocampal	NNP
work_dbbvwgi6and2fokqess5tojy2u	120	8	dentate	dentate	NN
work_dbbvwgi6and2fokqess5tojy2u	120	9	gyrus	gyrus	NNP
work_dbbvwgi6and2fokqess5tojy2u	120	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	121	1	DM	dm	VB
work_dbbvwgi6and2fokqess5tojy2u	121	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	121	3	dorsomedial	dorsomedial	JJ
work_dbbvwgi6and2fokqess5tojy2u	121	4	nucleus	nucleus	NN
work_dbbvwgi6and2fokqess5tojy2u	121	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	121	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	121	7	hypothalamus	hypothalamus	NN
work_dbbvwgi6and2fokqess5tojy2u	121	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	122	1	Pir	Pir	NNP
work_dbbvwgi6and2fokqess5tojy2u	122	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	122	3	piriform	piriform	NN
work_dbbvwgi6and2fokqess5tojy2u	122	4	cortex	cortex	NN
work_dbbvwgi6and2fokqess5tojy2u	122	5	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	123	1	PV	PV	NNP
work_dbbvwgi6and2fokqess5tojy2u	123	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	123	3	paraventricular	paraventricular	NNP
work_dbbvwgi6and2fokqess5tojy2u	123	4	thalamic	thalamic	JJ
work_dbbvwgi6and2fokqess5tojy2u	123	5	nucleus	nucleus	NN
work_dbbvwgi6and2fokqess5tojy2u	123	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	124	1	RSG	RSG	NNP
work_dbbvwgi6and2fokqess5tojy2u	124	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	124	3	retrosplenial	retrosplenial	JJ
work_dbbvwgi6and2fokqess5tojy2u	124	4	granular	granular	JJ
work_dbbvwgi6and2fokqess5tojy2u	124	5	cortex	cortex	NN
work_dbbvwgi6and2fokqess5tojy2u	124	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	125	1	VM	VM	NNP
work_dbbvwgi6and2fokqess5tojy2u	125	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	125	3	ventromedial	ventromedial	JJ
work_dbbvwgi6and2fokqess5tojy2u	125	4	nucleus	nucleus	NN
work_dbbvwgi6and2fokqess5tojy2u	125	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	125	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	125	7	hypothalamus	hypothalamus	NN
work_dbbvwgi6and2fokqess5tojy2u	125	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	126	1	Oncotarget56089www.impactjournals.com/oncotarget	oncotarget56089www.impactjournals.com/oncotarget	ADD
work_dbbvwgi6and2fokqess5tojy2u	126	2	It	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	126	3	had	have	VBD
work_dbbvwgi6and2fokqess5tojy2u	126	4	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	126	5	previously	previously	RB
work_dbbvwgi6and2fokqess5tojy2u	126	6	demonstrated	demonstrate	VBN
work_dbbvwgi6and2fokqess5tojy2u	126	7	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	126	8	knockout	knockout	JJ
work_dbbvwgi6and2fokqess5tojy2u	126	9	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	126	10	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	126	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	126	12	E3	E3	NNP
work_dbbvwgi6and2fokqess5tojy2u	126	13	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	126	14	ligases	ligase	NNS
work_dbbvwgi6and2fokqess5tojy2u	126	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	126	16	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	126	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	126	18	such	such	JJ
work_dbbvwgi6and2fokqess5tojy2u	126	19	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	126	20	MDM2	MDM2	NNP
work_dbbvwgi6and2fokqess5tojy2u	126	21	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	126	22	MDM4	MDM4	NNP
work_dbbvwgi6and2fokqess5tojy2u	126	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	126	24	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	126	25	lethal	lethal	JJ
work_dbbvwgi6and2fokqess5tojy2u	126	26	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	126	27	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	126	28	stages	stage	NNS
work_dbbvwgi6and2fokqess5tojy2u	126	29	due	due	JJ
work_dbbvwgi6and2fokqess5tojy2u	126	30	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	126	31	growth	growth	NN
work_dbbvwgi6and2fokqess5tojy2u	126	32	inhibition	inhibition	NN
work_dbbvwgi6and2fokqess5tojy2u	126	33	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	126	34	apoptosis	apoptosis	NN
work_dbbvwgi6and2fokqess5tojy2u	126	35	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	127	1	Interestingly	interestingly	RB
work_dbbvwgi6and2fokqess5tojy2u	127	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	127	3	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	127	4	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	127	5	could	could	MD
work_dbbvwgi6and2fokqess5tojy2u	127	6	be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	127	7	rescued	rescue	VBN
work_dbbvwgi6and2fokqess5tojy2u	127	8	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	127	9	concomitant	concomitant	JJ
work_dbbvwgi6and2fokqess5tojy2u	127	10	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	127	11	depletion	depletion	NN
work_dbbvwgi6and2fokqess5tojy2u	127	12	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	127	13	33	33	CD
work_dbbvwgi6and2fokqess5tojy2u	127	14	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	127	15	35	35	CD
work_dbbvwgi6and2fokqess5tojy2u	127	16	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	127	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	128	1	Because	because	IN
work_dbbvwgi6and2fokqess5tojy2u	128	2	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	128	3	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	128	4	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	128	5	E3	E3	NNP
work_dbbvwgi6and2fokqess5tojy2u	128	6	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	128	7	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	128	8	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	128	9	regulates	regulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	128	10	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	128	11	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	128	12	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	128	13	32	32	CD
work_dbbvwgi6and2fokqess5tojy2u	128	14	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	128	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	128	16	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	128	17	asked	ask	VBD
work_dbbvwgi6and2fokqess5tojy2u	128	18	whether	whether	IN
work_dbbvwgi6and2fokqess5tojy2u	128	19	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	128	20	inactivation	inactivation	NN
work_dbbvwgi6and2fokqess5tojy2u	128	21	might	may	MD
work_dbbvwgi6and2fokqess5tojy2u	128	22	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	128	23	rescue	rescue	VB
work_dbbvwgi6and2fokqess5tojy2u	128	24	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	128	25	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	128	26	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	128	27	Herc2530/530	Herc2530/530	``
work_dbbvwgi6and2fokqess5tojy2u	128	28	homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	128	29	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	128	30	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	129	1	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	129	2	crossed	cross	VBD
work_dbbvwgi6and2fokqess5tojy2u	129	3	double	double	JJ
work_dbbvwgi6and2fokqess5tojy2u	129	4	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	129	5	Herc2	herc2	NN
work_dbbvwgi6and2fokqess5tojy2u	129	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	129	7	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	129	8	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	129	9	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	129	10	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	129	11	p53+/-	p53+/-	JJ
work_dbbvwgi6and2fokqess5tojy2u	129	12	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	129	13	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	129	14	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	129	15	obtain	obtain	VB
work_dbbvwgi6and2fokqess5tojy2u	129	16	double	double	JJ
work_dbbvwgi6and2fokqess5tojy2u	129	17	homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	129	18	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	129	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	130	1	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	130	2	analyzed	analyze	VBD
work_dbbvwgi6and2fokqess5tojy2u	130	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	130	4	genotype	genotype	NN
work_dbbvwgi6and2fokqess5tojy2u	130	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	130	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	130	7	offspring	offspring	NN
work_dbbvwgi6and2fokqess5tojy2u	130	8	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	130	9	performing	perform	VBG
work_dbbvwgi6and2fokqess5tojy2u	130	10	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	130	11	adequate	adequate	JJ
work_dbbvwgi6and2fokqess5tojy2u	130	12	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	130	13	assay	assay	NN
work_dbbvwgi6and2fokqess5tojy2u	130	14	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	130	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	130	16	genomic	genomic	JJ
work_dbbvwgi6and2fokqess5tojy2u	130	17	DNA	dna	NN
work_dbbvwgi6and2fokqess5tojy2u	130	18	samples	sample	NNS
work_dbbvwgi6and2fokqess5tojy2u	130	19	but	but	CC
work_dbbvwgi6and2fokqess5tojy2u	130	20	did	do	VBD
work_dbbvwgi6and2fokqess5tojy2u	130	21	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	130	22	observe	observe	VB
work_dbbvwgi6and2fokqess5tojy2u	130	23	any	any	DT
work_dbbvwgi6and2fokqess5tojy2u	130	24	viable	viable	JJ
work_dbbvwgi6and2fokqess5tojy2u	130	25	Herc2530/530	Herc2530/530	``
work_dbbvwgi6and2fokqess5tojy2u	130	26	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	130	27	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	130	28	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	130	29	3C	3c	NN
work_dbbvwgi6and2fokqess5tojy2u	130	30	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	130	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	131	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	131	2	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	131	3	suggest	suggest	VBP
work_dbbvwgi6and2fokqess5tojy2u	131	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	131	5	non	non	JJ
work_dbbvwgi6and2fokqess5tojy2u	131	6	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	131	7	involvement	involvement	NN
work_dbbvwgi6and2fokqess5tojy2u	131	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	131	9	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	131	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	131	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	131	12	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	131	13	death	death	NN
work_dbbvwgi6and2fokqess5tojy2u	131	14	caused	cause	VBN
work_dbbvwgi6and2fokqess5tojy2u	131	15	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	131	16	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	131	17	depletion	depletion	NN
work_dbbvwgi6and2fokqess5tojy2u	131	18	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	131	19	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	131	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	132	1	Partial	partial	JJ
work_dbbvwgi6and2fokqess5tojy2u	132	2	inactivation	inactivation	NN
work_dbbvwgi6and2fokqess5tojy2u	132	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	132	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	132	5	Herc2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	132	6	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	132	7	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	132	8	sufficient	sufficient	JJ
work_dbbvwgi6and2fokqess5tojy2u	132	9	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	132	10	reduce	reduce	VB
work_dbbvwgi6and2fokqess5tojy2u	132	11	HErc2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	132	12	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	132	13	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	132	14	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	132	15	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	132	16	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	132	17	analyzed	analyze	VBD
work_dbbvwgi6and2fokqess5tojy2u	132	18	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	132	19	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	132	20	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	132	21	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	132	22	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	132	23	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	132	24	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	132	25	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	132	26	immunoblotting	immunoblotte	VBG
work_dbbvwgi6and2fokqess5tojy2u	132	27	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	133	1	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	133	2	observed	observe	VBD
work_dbbvwgi6and2fokqess5tojy2u	133	3	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	133	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	133	5	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	133	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	133	7	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	133	8	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	133	9	decreased	decrease	VBN
work_dbbvwgi6and2fokqess5tojy2u	133	10	approximately	approximately	RB
work_dbbvwgi6and2fokqess5tojy2u	133	11	50	50	CD
work_dbbvwgi6and2fokqess5tojy2u	133	12	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	133	13	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	133	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	133	15	brain	brain	NN
work_dbbvwgi6and2fokqess5tojy2u	133	16	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	133	17	kidney	kidney	NN
work_dbbvwgi6and2fokqess5tojy2u	133	18	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	133	19	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	133	20	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	133	21	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	133	22	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	133	23	4A	4A	NNP
work_dbbvwgi6and2fokqess5tojy2u	133	24	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	133	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	134	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	134	2	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	134	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	134	4	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	134	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	134	6	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	134	7	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	134	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	134	9	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	134	10	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	134	11	allows	allow	VBZ
work_dbbvwgi6and2fokqess5tojy2u	134	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	134	13	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	134	14	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	134	15	Herc2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	134	16	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	134	17	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	134	18	more	more	JJR
work_dbbvwgi6and2fokqess5tojy2u	134	19	detail	detail	NN
work_dbbvwgi6and2fokqess5tojy2u	134	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	135	1	Ubiquitous	ubiquitous	JJ
work_dbbvwgi6and2fokqess5tojy2u	135	2	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	135	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	135	4	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	135	5	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	135	6	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	135	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	135	8	all	all	DT
work_dbbvwgi6and2fokqess5tojy2u	135	9	tissues	tissue	NNS
work_dbbvwgi6and2fokqess5tojy2u	135	10	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	135	11	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	135	12	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	135	13	1D	1D	NNP
work_dbbvwgi6and2fokqess5tojy2u	135	14	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	135	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	136	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	136	2	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	136	3	brain	brain	NN
work_dbbvwgi6and2fokqess5tojy2u	136	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	136	5	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	136	6	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	136	7	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	136	8	higher	high	JJR
work_dbbvwgi6and2fokqess5tojy2u	136	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	136	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	136	11	hippocampus	hippocampus	NN
work_dbbvwgi6and2fokqess5tojy2u	136	12	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	136	13	pyramidal	pyramidal	JJ
work_dbbvwgi6and2fokqess5tojy2u	136	14	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	136	15	layer	layer	NN
work_dbbvwgi6and2fokqess5tojy2u	136	16	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	136	17	granular	granular	JJ
work_dbbvwgi6and2fokqess5tojy2u	136	18	layer	layer	NN
work_dbbvwgi6and2fokqess5tojy2u	136	19	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	136	20	dentate	dentate	NN
work_dbbvwgi6and2fokqess5tojy2u	136	21	gyrus	gyrus	NNP
work_dbbvwgi6and2fokqess5tojy2u	136	22	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	136	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	136	24	hypothalamic	hypothalamic	NNP
work_dbbvwgi6and2fokqess5tojy2u	136	25	nucleus	nucleus	NNP
work_dbbvwgi6and2fokqess5tojy2u	136	26	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	136	27	dorsomedial	dorsomedial	JJ
work_dbbvwgi6and2fokqess5tojy2u	136	28	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	136	29	ventromedial	ventromedial	JJ
work_dbbvwgi6and2fokqess5tojy2u	136	30	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	136	31	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	136	32	amygdaloid	amygdaloid	NNP
work_dbbvwgi6and2fokqess5tojy2u	136	33	nucleus	nucleus	NNP
work_dbbvwgi6and2fokqess5tojy2u	136	34	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	136	35	basal	basal	NNP
work_dbbvwgi6and2fokqess5tojy2u	136	36	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	136	37	medial	medial	NNP
work_dbbvwgi6and2fokqess5tojy2u	136	38	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	136	39	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	136	40	piriform	piriform	NNP
work_dbbvwgi6and2fokqess5tojy2u	136	41	cortex	cortex	NN
work_dbbvwgi6and2fokqess5tojy2u	136	42	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	136	43	dorsal	dorsal	NN
work_dbbvwgi6and2fokqess5tojy2u	136	44	endopiriform	endopiriform	NN
work_dbbvwgi6and2fokqess5tojy2u	136	45	nucleus	nucleus	NNP
work_dbbvwgi6and2fokqess5tojy2u	136	46	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	136	47	entorhinal	entorhinal	JJ
work_dbbvwgi6and2fokqess5tojy2u	136	48	cortex	cortex	NN
work_dbbvwgi6and2fokqess5tojy2u	136	49	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	136	50	retrospenial	retrospenial	JJ
work_dbbvwgi6and2fokqess5tojy2u	136	51	cortex	cortex	NNP
work_dbbvwgi6and2fokqess5tojy2u	136	52	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	136	53	paraventricular	paraventricular	NNP
work_dbbvwgi6and2fokqess5tojy2u	136	54	thalamic	thalamic	NNP
work_dbbvwgi6and2fokqess5tojy2u	136	55	nucleus	nucleus	NN
work_dbbvwgi6and2fokqess5tojy2u	136	56	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	136	57	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	136	58	cerebellum	cerebellum	NN
work_dbbvwgi6and2fokqess5tojy2u	136	59	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	136	60	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	136	61	4B	4b	NN
work_dbbvwgi6and2fokqess5tojy2u	136	62	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	136	63	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	136	64	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	136	65	shown	show	VBN
work_dbbvwgi6and2fokqess5tojy2u	136	66	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	136	67	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	137	1	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	137	2	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	137	3	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	137	4	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	137	5	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	137	6	show	show	VB
work_dbbvwgi6and2fokqess5tojy2u	137	7	reduced	reduced	JJ
work_dbbvwgi6and2fokqess5tojy2u	137	8	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	137	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	137	10	HErc2	HErc2	NNP
work_dbbvwgi6and2fokqess5tojy2u	137	11	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	138	1	A.	A.	NNP
work_dbbvwgi6and2fokqess5tojy2u	138	2	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	138	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	138	4	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	138	5	substrate	substrate	NN
work_dbbvwgi6and2fokqess5tojy2u	138	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	138	7	ubiquitination	ubiquitination	NN
work_dbbvwgi6and2fokqess5tojy2u	138	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	138	9	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	138	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	138	11	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	138	12	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	138	13	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	138	14	lysates	lysates	NNP
work_dbbvwgi6and2fokqess5tojy2u	138	15	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	138	16	cerebellum	cerebellum	NN
work_dbbvwgi6and2fokqess5tojy2u	138	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	138	18	cerebral	cerebral	NNP
work_dbbvwgi6and2fokqess5tojy2u	138	19	cortex	cortex	NNP
work_dbbvwgi6and2fokqess5tojy2u	138	20	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	138	21	diencephalon	diencephalon	NNP
work_dbbvwgi6and2fokqess5tojy2u	138	22	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	138	23	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	138	24	8	8	CD
work_dbbvwgi6and2fokqess5tojy2u	138	25	week	week	NN
work_dbbvwgi6and2fokqess5tojy2u	138	26	old	old	JJ
work_dbbvwgi6and2fokqess5tojy2u	138	27	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	138	28	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	138	29	immunoblotting	immunoblotte	VBG
work_dbbvwgi6and2fokqess5tojy2u	138	30	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	139	1	Higher	high	JJR
work_dbbvwgi6and2fokqess5tojy2u	139	2	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	139	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	139	4	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	139	5	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	139	6	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	139	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	139	8	all	all	DT
work_dbbvwgi6and2fokqess5tojy2u	139	9	areas	area	NNS
work_dbbvwgi6and2fokqess5tojy2u	139	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	139	11	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	139	12	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	139	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	140	1	Levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	140	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	140	3	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	140	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	140	5	quantified	quantify	VBN
work_dbbvwgi6and2fokqess5tojy2u	140	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	140	7	normalized	normalize	VBN
work_dbbvwgi6and2fokqess5tojy2u	140	8	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	140	9	respect	respect	NN
work_dbbvwgi6and2fokqess5tojy2u	140	10	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	140	11	β	β	NN
work_dbbvwgi6and2fokqess5tojy2u	140	12	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	140	13	actin	actin	NN
work_dbbvwgi6and2fokqess5tojy2u	140	14	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	140	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	141	1	b.	b.	NNP
work_dbbvwgi6and2fokqess5tojy2u	141	2	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	141	3	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	141	4	show	show	VBP
work_dbbvwgi6and2fokqess5tojy2u	141	5	reduced	reduced	JJ
work_dbbvwgi6and2fokqess5tojy2u	141	6	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	141	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	141	8	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	141	9	mRNA	mrna	NN
work_dbbvwgi6and2fokqess5tojy2u	141	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	142	1	RT	RT	NNP
work_dbbvwgi6and2fokqess5tojy2u	142	2	quantitative	quantitative	NN
work_dbbvwgi6and2fokqess5tojy2u	142	3	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	142	4	analyses	analysis	NNS
work_dbbvwgi6and2fokqess5tojy2u	142	5	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	142	6	performed	perform	VBN
work_dbbvwgi6and2fokqess5tojy2u	142	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	142	8	forebrain	forebrain	NN
work_dbbvwgi6and2fokqess5tojy2u	142	9	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	142	10	cerebellum	cerebellum	NN
work_dbbvwgi6and2fokqess5tojy2u	142	11	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	142	12	Herc2+/+	Herc2+/+	NNP
work_dbbvwgi6and2fokqess5tojy2u	142	13	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	142	14	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	142	15	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	142	16	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	142	17	quantify	quantify	VB
work_dbbvwgi6and2fokqess5tojy2u	142	18	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	142	19	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	142	20	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	142	21	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	142	22	n	n	NNP
work_dbbvwgi6and2fokqess5tojy2u	142	23	=	=	SYM
work_dbbvwgi6and2fokqess5tojy2u	142	24	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	142	25	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	142	26	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	143	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	143	2	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	143	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	143	4	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	143	5	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	143	6	normalized	normalize	VBN
work_dbbvwgi6and2fokqess5tojy2u	143	7	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	143	8	respect	respect	NN
work_dbbvwgi6and2fokqess5tojy2u	143	9	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	143	10	GAPDH	GAPDH	NNP
work_dbbvwgi6and2fokqess5tojy2u	143	11	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	143	12	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	143	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	144	1	Oncotarget56090www.impactjournals.com/oncotarget	Oncotarget56090www.impactjournals.com/oncotarget	``
work_dbbvwgi6and2fokqess5tojy2u	144	2	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	144	3	observations	observation	NNS
work_dbbvwgi6and2fokqess5tojy2u	144	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	144	5	confirmed	confirm	VBN
work_dbbvwgi6and2fokqess5tojy2u	144	6	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	144	7	immunoblotting	immunoblotte	VBG
work_dbbvwgi6and2fokqess5tojy2u	144	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	145	1	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	145	2	dissected	dissect	VBD
work_dbbvwgi6and2fokqess5tojy2u	145	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	145	4	cerebellum	cerebellum	NN
work_dbbvwgi6and2fokqess5tojy2u	145	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	145	6	cerebral	cerebral	NNP
work_dbbvwgi6and2fokqess5tojy2u	145	7	cortex	cortex	NNP
work_dbbvwgi6and2fokqess5tojy2u	145	8	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	145	9	diencephalon	diencephalon	NNP
work_dbbvwgi6and2fokqess5tojy2u	145	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	145	11	detecting	detect	VBG
work_dbbvwgi6and2fokqess5tojy2u	145	12	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	145	13	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	145	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	145	15	all	all	PDT
work_dbbvwgi6and2fokqess5tojy2u	145	16	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	145	17	areas	area	NNS
work_dbbvwgi6and2fokqess5tojy2u	145	18	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	145	19	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	145	20	4C	4c	NN
work_dbbvwgi6and2fokqess5tojy2u	145	21	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	145	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	146	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	146	2	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	146	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	146	4	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	146	5	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	146	6	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	146	7	reduced	reduce	VBN
work_dbbvwgi6and2fokqess5tojy2u	146	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	146	9	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	146	10	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	146	11	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	146	12	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	146	13	4C	4c	NN
work_dbbvwgi6and2fokqess5tojy2u	146	14	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	146	15	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	146	16	respect	respect	NN
work_dbbvwgi6and2fokqess5tojy2u	146	17	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	146	18	control	control	VB
work_dbbvwgi6and2fokqess5tojy2u	146	19	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	146	20	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	146	21	Herc2+/+	Herc2+/+	NNP
work_dbbvwgi6and2fokqess5tojy2u	146	22	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	146	23	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	147	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	147	2	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	147	3	show	show	VBP
work_dbbvwgi6and2fokqess5tojy2u	147	4	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	147	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	147	6	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	147	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	147	8	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	147	9	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	147	10	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	147	11	reduced	reduce	VBN
work_dbbvwgi6and2fokqess5tojy2u	147	12	almost	almost	RB
work_dbbvwgi6and2fokqess5tojy2u	147	13	50	50	CD
work_dbbvwgi6and2fokqess5tojy2u	147	14	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	147	15	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	147	16	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	147	17	mice	mice	NN
work_dbbvwgi6and2fokqess5tojy2u	147	18	tissues	tissue	NNS
work_dbbvwgi6and2fokqess5tojy2u	147	19	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	147	20	suggest	suggest	VBP
work_dbbvwgi6and2fokqess5tojy2u	147	21	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	147	22	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	147	23	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	147	24	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	147	25	must	must	MD
work_dbbvwgi6and2fokqess5tojy2u	147	26	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	147	27	decrease	decrease	VB
work_dbbvwgi6and2fokqess5tojy2u	147	28	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	147	29	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	147	30	brain	brain	NN
work_dbbvwgi6and2fokqess5tojy2u	147	31	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	147	32	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	147	33	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	147	34	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	148	1	Two	two	CD
work_dbbvwgi6and2fokqess5tojy2u	148	2	activities	activity	NNS
work_dbbvwgi6and2fokqess5tojy2u	148	3	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	148	4	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	148	5	associated	associate	VBN
work_dbbvwgi6and2fokqess5tojy2u	148	6	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	148	7	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	148	8	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	148	9	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	148	10	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	148	11	E3	E3	NNP
work_dbbvwgi6and2fokqess5tojy2u	148	12	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	148	13	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	148	14	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	148	15	which	which	WDT
work_dbbvwgi6and2fokqess5tojy2u	148	16	regulates	regulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	148	17	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	148	18	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	148	19	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	148	20	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	148	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	148	22	BRCA1	brca1	NN
work_dbbvwgi6and2fokqess5tojy2u	148	23	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	148	24	XPA	XPA	NNP
work_dbbvwgi6and2fokqess5tojy2u	148	25	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	148	26	21	21	CD
work_dbbvwgi6and2fokqess5tojy2u	148	27	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	148	28	22	22	CD
work_dbbvwgi6and2fokqess5tojy2u	148	29	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	148	30	25	25	CD
work_dbbvwgi6and2fokqess5tojy2u	148	31	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	148	32	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	148	33	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	148	34	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	148	35	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	148	36	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	148	37	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	148	38	stimulator	stimulator	NN
work_dbbvwgi6and2fokqess5tojy2u	148	39	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	148	40	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	148	41	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	148	42	oligomerization	oligomerization	NN
work_dbbvwgi6and2fokqess5tojy2u	148	43	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	148	44	regulates	regulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	148	45	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	148	46	transcriptional	transcriptional	JJ
work_dbbvwgi6and2fokqess5tojy2u	148	47	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	148	48	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	148	49	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	148	50	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	148	51	32	32	CD
work_dbbvwgi6and2fokqess5tojy2u	148	52	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	148	53	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	149	1	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	149	2	analyze	analyze	VB
work_dbbvwgi6and2fokqess5tojy2u	149	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	149	4	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	149	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	149	6	E3	E3	NNP
work_dbbvwgi6and2fokqess5tojy2u	149	7	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	149	8	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	149	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	149	10	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	149	11	performed	perform	VBD
work_dbbvwgi6and2fokqess5tojy2u	149	12	immunoblotting	immunoblotte	VBG
work_dbbvwgi6and2fokqess5tojy2u	149	13	experiments	experiment	NNS
work_dbbvwgi6and2fokqess5tojy2u	149	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	149	15	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	149	16	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	149	17	brain	brain	NN
work_dbbvwgi6and2fokqess5tojy2u	149	18	areas	area	NNS
work_dbbvwgi6and2fokqess5tojy2u	149	19	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	149	20	antibodies	antibody	NNS
work_dbbvwgi6and2fokqess5tojy2u	149	21	against	against	IN
work_dbbvwgi6and2fokqess5tojy2u	149	22	substrates	substrate	NNS
work_dbbvwgi6and2fokqess5tojy2u	149	23	ubiquitinated	ubiquitinate	VBN
work_dbbvwgi6and2fokqess5tojy2u	149	24	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	149	25	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	149	26	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	150	1	Only	only	RB
work_dbbvwgi6and2fokqess5tojy2u	150	2	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	150	3	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	150	4	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	150	5	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	150	6	detected	detect	VBN
work_dbbvwgi6and2fokqess5tojy2u	150	7	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	150	8	immunoblotting	immunoblotte	VBG
work_dbbvwgi6and2fokqess5tojy2u	150	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	150	10	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	150	11	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	150	12	samples	sample	NNS
work_dbbvwgi6and2fokqess5tojy2u	150	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	150	14	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	150	15	5A	5a	RB
work_dbbvwgi6and2fokqess5tojy2u	150	16	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	150	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	151	1	Interestingly	interestingly	RB
work_dbbvwgi6and2fokqess5tojy2u	151	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	151	3	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	151	4	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	151	5	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	151	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	151	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	151	8	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	151	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	151	10	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	151	11	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	151	12	higher	high	JJR
work_dbbvwgi6and2fokqess5tojy2u	151	13	than	than	IN
work_dbbvwgi6and2fokqess5tojy2u	151	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	151	15	control	control	NN
work_dbbvwgi6and2fokqess5tojy2u	151	16	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	151	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	152	1	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	152	2	examine	examine	VB
work_dbbvwgi6and2fokqess5tojy2u	152	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	152	4	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	152	5	stimulating	stimulate	VBG
work_dbbvwgi6and2fokqess5tojy2u	152	6	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	152	7	oligomerization	oligomerization	NN
work_dbbvwgi6and2fokqess5tojy2u	152	8	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	152	9	transcriptional	transcriptional	JJ
work_dbbvwgi6and2fokqess5tojy2u	152	10	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	152	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	152	12	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	152	13	analyzed	analyze	VBD
work_dbbvwgi6and2fokqess5tojy2u	152	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	152	15	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	152	16	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	152	17	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	152	18	mRNA	mrna	NN
work_dbbvwgi6and2fokqess5tojy2u	152	19	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	152	20	RT	RT	NNP
work_dbbvwgi6and2fokqess5tojy2u	152	21	quantitative	quantitative	JJ
work_dbbvwgi6and2fokqess5tojy2u	152	22	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	152	23	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	152	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	153	1	A	a	DT
work_dbbvwgi6and2fokqess5tojy2u	153	2	decrease	decrease	NN
work_dbbvwgi6and2fokqess5tojy2u	153	3	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	153	4	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	153	5	mRNA	mrna	NN
work_dbbvwgi6and2fokqess5tojy2u	153	6	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	153	7	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	153	8	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	153	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	153	10	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	153	11	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	153	12	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	153	13	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	153	14	5B	5b	NN
work_dbbvwgi6and2fokqess5tojy2u	153	15	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	153	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	154	1	Altogether	altogether	RB
work_dbbvwgi6and2fokqess5tojy2u	154	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	154	3	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	154	4	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	154	5	show	show	VBP
work_dbbvwgi6and2fokqess5tojy2u	154	6	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	154	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	154	8	partial	partial	JJ
work_dbbvwgi6and2fokqess5tojy2u	154	9	inactivation	inactivation	NN
work_dbbvwgi6and2fokqess5tojy2u	154	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	154	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	154	12	Herc2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	154	13	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	154	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	154	15	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	154	16	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	154	17	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	154	18	sufficient	sufficient	JJ
work_dbbvwgi6and2fokqess5tojy2u	154	19	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	154	20	reduce	reduce	VB
work_dbbvwgi6and2fokqess5tojy2u	154	21	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	154	22	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	154	23	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	154	24	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	154	25	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	154	26	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	155	1	A	a	DT
work_dbbvwgi6and2fokqess5tojy2u	155	2	homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	155	3	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	155	4	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	155	5	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	155	6	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	155	7	causes	cause	VBZ
work_dbbvwgi6and2fokqess5tojy2u	155	8	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	155	9	Angelman	Angelman	NNP
work_dbbvwgi6and2fokqess5tojy2u	155	10	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	155	11	like	like	JJ
work_dbbvwgi6and2fokqess5tojy2u	155	12	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	155	13	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	155	14	reduces	reduce	VBZ
work_dbbvwgi6and2fokqess5tojy2u	155	15	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	155	16	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	155	17	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	155	18	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	155	19	HErc2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	155	20	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	155	21	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	155	22	has	have	VBZ
work_dbbvwgi6and2fokqess5tojy2u	155	23	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	155	24	implicated	implicate	VBN
work_dbbvwgi6and2fokqess5tojy2u	155	25	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	155	26	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	155	27	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	155	28	disorder	disorder	NN
work_dbbvwgi6and2fokqess5tojy2u	155	29	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	155	30	some	some	DT
work_dbbvwgi6and2fokqess5tojy2u	155	31	features	feature	NNS
work_dbbvwgi6and2fokqess5tojy2u	155	32	similar	similar	JJ
work_dbbvwgi6and2fokqess5tojy2u	155	33	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	155	34	Angelman	Angelman	NNP
work_dbbvwgi6and2fokqess5tojy2u	155	35	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	155	36	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	156	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	156	2	substitution	substitution	NN
work_dbbvwgi6and2fokqess5tojy2u	156	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	156	4	proline	proline	NN
work_dbbvwgi6and2fokqess5tojy2u	156	5	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	156	6	leucine	leucine	NNP
work_dbbvwgi6and2fokqess5tojy2u	156	7	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	156	8	amino	amino	JJ
work_dbbvwgi6and2fokqess5tojy2u	156	9	acid	acid	NNP
work_dbbvwgi6and2fokqess5tojy2u	156	10	position	position	NNP
work_dbbvwgi6and2fokqess5tojy2u	156	11	594	594	CD
work_dbbvwgi6and2fokqess5tojy2u	156	12	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	156	13	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	156	14	caused	cause	VBN
work_dbbvwgi6and2fokqess5tojy2u	156	15	HERC2P594L	HERC2P594L	NNP
work_dbbvwgi6and2fokqess5tojy2u	156	16	instability	instability	NN
work_dbbvwgi6and2fokqess5tojy2u	156	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	156	18	almost	almost	RB
work_dbbvwgi6and2fokqess5tojy2u	156	19	total	total	JJ
work_dbbvwgi6and2fokqess5tojy2u	156	20	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	156	21	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	156	22	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	156	23	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	156	24	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	156	25	homozygosis	homozygosis	NN
work_dbbvwgi6and2fokqess5tojy2u	156	26	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	156	27	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	156	28	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	156	29	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	156	30	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	156	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	157	1	Based	base	VBN
work_dbbvwgi6and2fokqess5tojy2u	157	2	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	157	3	our	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	157	4	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	157	5	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	157	6	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	157	7	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	157	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	157	9	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	157	10	hypothesized	hypothesize	VBD
work_dbbvwgi6and2fokqess5tojy2u	157	11	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	157	12	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	157	13	patients	patient	NNS
work_dbbvwgi6and2fokqess5tojy2u	157	14	would	would	MD
work_dbbvwgi6and2fokqess5tojy2u	157	15	have	have	VB
work_dbbvwgi6and2fokqess5tojy2u	157	16	lower	low	JJR
work_dbbvwgi6and2fokqess5tojy2u	157	17	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	157	18	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	157	19	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	157	20	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	157	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	158	1	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	158	2	test	test	VB
work_dbbvwgi6and2fokqess5tojy2u	158	3	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	158	4	hypothesis	hypothesis	NN
work_dbbvwgi6and2fokqess5tojy2u	158	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	158	6	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	158	7	analyzed	analyze	VBD
work_dbbvwgi6and2fokqess5tojy2u	158	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	158	9	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	158	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	158	11	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	158	12	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	158	13	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	158	14	fibroblasts	fibroblast	NNS
work_dbbvwgi6and2fokqess5tojy2u	158	15	derived	derive	VBN
work_dbbvwgi6and2fokqess5tojy2u	158	16	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	158	17	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	158	18	affected	affect	VBN
work_dbbvwgi6and2fokqess5tojy2u	158	19	individual	individual	NN
work_dbbvwgi6and2fokqess5tojy2u	158	20	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	158	21	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	158	22	healthy	healthy	JJ
work_dbbvwgi6and2fokqess5tojy2u	158	23	control	control	NN
work_dbbvwgi6and2fokqess5tojy2u	158	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	159	1	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	159	2	observed	observe	VBD
work_dbbvwgi6and2fokqess5tojy2u	159	3	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	159	4	high	high	JJ
work_dbbvwgi6and2fokqess5tojy2u	159	5	increase	increase	NN
work_dbbvwgi6and2fokqess5tojy2u	159	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	159	7	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	159	8	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	159	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	159	10	fibroblasts	fibroblast	NNS
work_dbbvwgi6and2fokqess5tojy2u	159	11	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	159	12	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	159	13	patient	patient	NN
work_dbbvwgi6and2fokqess5tojy2u	159	14	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	159	15	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	159	16	6A	6a	NN
work_dbbvwgi6and2fokqess5tojy2u	159	17	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	159	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	160	1	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	160	2	confirm	confirm	VB
work_dbbvwgi6and2fokqess5tojy2u	160	3	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	160	4	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	160	5	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	160	6	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	160	7	diminished	diminish	VBN
work_dbbvwgi6and2fokqess5tojy2u	160	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	160	9	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	160	10	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	160	11	analyzed	analyze	VBD
work_dbbvwgi6and2fokqess5tojy2u	160	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	160	13	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	160	14	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	160	15	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	160	16	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	160	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	161	1	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	161	2	observed	observe	VBD
work_dbbvwgi6and2fokqess5tojy2u	161	3	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	161	4	decrease	decrease	NN
work_dbbvwgi6and2fokqess5tojy2u	161	5	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	161	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	161	7	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	161	8	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	161	9	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	161	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	161	11	fibroblasts	fibroblast	NNS
work_dbbvwgi6and2fokqess5tojy2u	161	12	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	161	13	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	161	14	patient	patient	NN
work_dbbvwgi6and2fokqess5tojy2u	161	15	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	161	16	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	161	17	6A	6a	NN
work_dbbvwgi6and2fokqess5tojy2u	161	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	161	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	162	1	However	however	RB
work_dbbvwgi6and2fokqess5tojy2u	162	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	162	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	162	4	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	162	5	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	162	6	α	α	CD
work_dbbvwgi6and2fokqess5tojy2u	162	7	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	162	8	tubulin	tubulin	NN
work_dbbvwgi6and2fokqess5tojy2u	162	9	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	162	10	did	do	VBD
work_dbbvwgi6and2fokqess5tojy2u	162	11	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	162	12	significantly	significantly	RB
work_dbbvwgi6and2fokqess5tojy2u	162	13	change	change	VB
work_dbbvwgi6and2fokqess5tojy2u	162	14	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	163	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	163	2	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	163	3	mRNA	mrna	NN
work_dbbvwgi6and2fokqess5tojy2u	163	4	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	163	5	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	163	6	confirmed	confirm	VBD
work_dbbvwgi6and2fokqess5tojy2u	163	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	163	8	decrease	decrease	NN
work_dbbvwgi6and2fokqess5tojy2u	163	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	163	10	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	163	11	transcriptional	transcriptional	JJ
work_dbbvwgi6and2fokqess5tojy2u	163	12	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	163	13	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	163	14	fibroblasts	fibroblast	NNS
work_dbbvwgi6and2fokqess5tojy2u	163	15	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	163	16	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	163	17	patient	patient	NN
work_dbbvwgi6and2fokqess5tojy2u	163	18	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	163	19	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	163	20	6B	6b	NN
work_dbbvwgi6and2fokqess5tojy2u	163	21	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	163	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	164	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	164	2	level	level	NN
work_dbbvwgi6and2fokqess5tojy2u	164	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	164	4	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	164	5	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	164	6	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	164	7	regulated	regulate	VBN
work_dbbvwgi6and2fokqess5tojy2u	164	8	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	164	9	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	164	10	proteasome	proteasome	NN
work_dbbvwgi6and2fokqess5tojy2u	164	11	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	165	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	165	2	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	165	3	presence	presence	NN
work_dbbvwgi6and2fokqess5tojy2u	165	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	165	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	165	6	proteasome	proteasome	JJ
work_dbbvwgi6and2fokqess5tojy2u	165	7	inhibitor	inhibitor	NN
work_dbbvwgi6and2fokqess5tojy2u	165	8	MG132	mg132	NN
work_dbbvwgi6and2fokqess5tojy2u	165	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	165	10	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	165	11	observed	observe	VBD
work_dbbvwgi6and2fokqess5tojy2u	165	12	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	165	13	similar	similar	JJ
work_dbbvwgi6and2fokqess5tojy2u	165	14	stabilization	stabilization	NN
work_dbbvwgi6and2fokqess5tojy2u	165	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	165	16	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	165	17	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	165	18	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	165	19	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	165	20	fibroblasts	fibroblast	NNS
work_dbbvwgi6and2fokqess5tojy2u	165	21	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	165	22	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	165	23	patient	patient	NN
work_dbbvwgi6and2fokqess5tojy2u	165	24	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	165	25	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	165	26	control	control	NN
work_dbbvwgi6and2fokqess5tojy2u	165	27	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	165	28	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	165	29	6C	6c	NN
work_dbbvwgi6and2fokqess5tojy2u	165	30	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	165	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	166	1	Under	under	IN
work_dbbvwgi6and2fokqess5tojy2u	166	2	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	166	3	conditions	condition	NNS
work_dbbvwgi6and2fokqess5tojy2u	166	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	166	5	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	166	6	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	166	7	detected	detect	VBD
work_dbbvwgi6and2fokqess5tojy2u	166	8	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	166	9	decrease	decrease	NN
work_dbbvwgi6and2fokqess5tojy2u	166	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	166	11	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	166	12	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	166	13	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	166	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	166	15	fibroblasts	fibroblast	NNS
work_dbbvwgi6and2fokqess5tojy2u	166	16	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	166	17	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	166	18	patient	patient	NN
work_dbbvwgi6and2fokqess5tojy2u	166	19	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	166	20	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	166	21	6C	6c	NN
work_dbbvwgi6and2fokqess5tojy2u	166	22	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	166	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	166	24	indicating	indicate	VBG
work_dbbvwgi6and2fokqess5tojy2u	166	25	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	166	26	decrease	decrease	NN
work_dbbvwgi6and2fokqess5tojy2u	166	27	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	166	28	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	166	29	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	166	30	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	166	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	167	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	167	2	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	167	3	show	show	VBP
work_dbbvwgi6and2fokqess5tojy2u	167	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	167	5	low	low	JJ
work_dbbvwgi6and2fokqess5tojy2u	167	6	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	167	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	167	8	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	167	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	167	10	individuals	individual	NNS
work_dbbvwgi6and2fokqess5tojy2u	167	11	carrying	carry	VBG
work_dbbvwgi6and2fokqess5tojy2u	167	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	167	13	HERC2P594L	HERC2P594L	NNP
work_dbbvwgi6and2fokqess5tojy2u	167	14	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	167	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	168	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	168	2	conclusion	conclusion	NN
work_dbbvwgi6and2fokqess5tojy2u	168	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	168	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	168	5	low	low	JJ
work_dbbvwgi6and2fokqess5tojy2u	168	6	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	168	7	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	168	8	found	find	VBN
work_dbbvwgi6and2fokqess5tojy2u	168	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	168	10	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	168	11	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	168	12	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	168	13	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	168	14	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	168	15	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	168	16	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	168	17	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	168	18	individuals	individual	NNS
work_dbbvwgi6and2fokqess5tojy2u	168	19	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	168	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	168	21	HERC2P594L	HERC2P594L	NNP
work_dbbvwgi6and2fokqess5tojy2u	168	22	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	168	23	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	168	24	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	168	25	6A-6C	6a-6c	CD
work_dbbvwgi6and2fokqess5tojy2u	168	26	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	168	27	correlated	correlate	VBD
work_dbbvwgi6and2fokqess5tojy2u	168	28	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	168	29	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	168	30	increase	increase	NN
work_dbbvwgi6and2fokqess5tojy2u	168	31	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	168	32	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	168	33	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	168	34	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	168	35	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	168	36	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	168	37	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	168	38	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	168	39	decrease	decrease	NN
work_dbbvwgi6and2fokqess5tojy2u	168	40	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	168	41	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	168	42	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	168	43	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	168	44	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	168	45	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	168	46	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	169	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	169	2	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	169	3	suggest	suggest	VBP
work_dbbvwgi6and2fokqess5tojy2u	169	4	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	169	5	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	169	6	conditions	condition	NNS
work_dbbvwgi6and2fokqess5tojy2u	169	7	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	169	8	low	low	JJ
work_dbbvwgi6and2fokqess5tojy2u	169	9	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	169	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	169	11	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	169	12	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	169	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	169	14	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	169	15	could	could	MD
work_dbbvwgi6and2fokqess5tojy2u	169	16	contain	contain	VB
work_dbbvwgi6and2fokqess5tojy2u	169	17	more	more	JJR
work_dbbvwgi6and2fokqess5tojy2u	169	18	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	169	19	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	169	20	less	less	JJR
work_dbbvwgi6and2fokqess5tojy2u	169	21	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	169	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	170	1	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	170	2	confirm	confirm	VB
work_dbbvwgi6and2fokqess5tojy2u	170	3	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	170	4	point	point	NN
work_dbbvwgi6and2fokqess5tojy2u	170	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	170	6	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	170	7	U2OS	U2OS	NNP
work_dbbvwgi6and2fokqess5tojy2u	170	8	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	170	9	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	170	10	depleted	deplete	VBN
work_dbbvwgi6and2fokqess5tojy2u	170	11	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	170	12	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	170	13	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	170	14	interference	interference	NN
work_dbbvwgi6and2fokqess5tojy2u	170	15	RNA	RNA	NNP
work_dbbvwgi6and2fokqess5tojy2u	170	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	170	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	170	18	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	170	19	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	170	20	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	170	21	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	170	22	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	170	23	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	170	24	immunoblotting	immunoblotte	VBG
work_dbbvwgi6and2fokqess5tojy2u	170	25	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	170	26	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	170	27	6D	6d	NN
work_dbbvwgi6and2fokqess5tojy2u	170	28	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	170	29	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	171	1	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	171	2	knockdown	knockdown	VBD
work_dbbvwgi6and2fokqess5tojy2u	171	3	increased	increase	VBN
work_dbbvwgi6and2fokqess5tojy2u	171	4	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	171	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	171	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	171	7	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	171	8	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	171	9	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	171	10	decreased	decrease	VBD
work_dbbvwgi6and2fokqess5tojy2u	171	11	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	171	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	171	13	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	171	14	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	171	15	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	171	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	172	1	table	table	NN
work_dbbvwgi6and2fokqess5tojy2u	172	2	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	172	3	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	172	4	behavioural	behavioural	JJ
work_dbbvwgi6and2fokqess5tojy2u	172	5	tests	test	NNS
work_dbbvwgi6and2fokqess5tojy2u	172	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	172	7	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	8	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	172	9	cognitive	cognitive	JJ
work_dbbvwgi6and2fokqess5tojy2u	172	10	task	task	NN
work_dbbvwgi6and2fokqess5tojy2u	172	11	behavioural	behavioural	JJ
work_dbbvwgi6and2fokqess5tojy2u	172	12	tests	test	NNS
work_dbbvwgi6and2fokqess5tojy2u	172	13	test	test	NN
work_dbbvwgi6and2fokqess5tojy2u	172	14	Values	value	NNS
work_dbbvwgi6and2fokqess5tojy2u	172	15	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	172	16	mean	mean	VB
work_dbbvwgi6and2fokqess5tojy2u	172	17	±	±	JJ
work_dbbvwgi6and2fokqess5tojy2u	172	18	error	error	NN
work_dbbvwgi6and2fokqess5tojy2u	172	19	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	20	n	n	NN
work_dbbvwgi6and2fokqess5tojy2u	172	21	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	22	P	p	NN
work_dbbvwgi6and2fokqess5tojy2u	172	23	value	value	NN
work_dbbvwgi6and2fokqess5tojy2u	172	24	Herc2+/+	Herc2+/+	NNS
work_dbbvwgi6and2fokqess5tojy2u	172	25	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	26	Anxiety	Anxiety	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	27	Time	Time	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	28	outside	outside	IN
work_dbbvwgi6and2fokqess5tojy2u	172	29	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	172	30	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	172	31	dark	dark	JJ
work_dbbvwgi6and2fokqess5tojy2u	172	32	box	box	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	33	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	34	s	s	NN
work_dbbvwgi6and2fokqess5tojy2u	172	35	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	36	235	235	CD
work_dbbvwgi6and2fokqess5tojy2u	172	37	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	38	13	13	CD
work_dbbvwgi6and2fokqess5tojy2u	172	39	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	40	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	172	41	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	42	232	232	CD
work_dbbvwgi6and2fokqess5tojy2u	172	43	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	44	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	172	45	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	46	8)	8)	CD
work_dbbvwgi6and2fokqess5tojy2u	172	47	0.83	0.83	CD
work_dbbvwgi6and2fokqess5tojy2u	172	48	Immobile	Immobile	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	49	time	time	NN
work_dbbvwgi6and2fokqess5tojy2u	172	50	suspended	suspend	VBN
work_dbbvwgi6and2fokqess5tojy2u	172	51	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	172	52	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	172	53	tail	tail	NN
work_dbbvwgi6and2fokqess5tojy2u	172	54	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	55	s	s	NN
work_dbbvwgi6and2fokqess5tojy2u	172	56	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	57	205	205	CD
work_dbbvwgi6and2fokqess5tojy2u	172	58	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	59	14	14	CD
work_dbbvwgi6and2fokqess5tojy2u	172	60	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	61	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	172	62	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	63	173	173	CD
work_dbbvwgi6and2fokqess5tojy2u	172	64	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	65	14	14	CD
work_dbbvwgi6and2fokqess5tojy2u	172	66	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	67	19	19	CD
work_dbbvwgi6and2fokqess5tojy2u	172	68	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	69	0.11	0.11	CD
work_dbbvwgi6and2fokqess5tojy2u	172	70	Learning	learning	NN
work_dbbvwgi6and2fokqess5tojy2u	172	71	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	172	72	Memory	Memory	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	73	Object	object	NN
work_dbbvwgi6and2fokqess5tojy2u	172	74	recognition	recognition	NN
work_dbbvwgi6and2fokqess5tojy2u	172	75	memory	memory	NN
work_dbbvwgi6and2fokqess5tojy2u	172	76	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	77	DI	DI	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	78	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	79	STM	STM	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	80	0.24	0.24	CD
work_dbbvwgi6and2fokqess5tojy2u	172	81	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	82	0.08	0.08	CD
work_dbbvwgi6and2fokqess5tojy2u	172	83	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	84	6	6	CD
work_dbbvwgi6and2fokqess5tojy2u	172	85	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	86	0.23	0.23	CD
work_dbbvwgi6and2fokqess5tojy2u	172	87	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	88	0.05	0.05	CD
work_dbbvwgi6and2fokqess5tojy2u	172	89	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	90	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	172	91	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	92	0.87	0.87	CD
work_dbbvwgi6and2fokqess5tojy2u	172	93	LTM	LTM	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	94	0.26	0.26	CD
work_dbbvwgi6and2fokqess5tojy2u	172	95	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	96	0.09	0.09	CD
work_dbbvwgi6and2fokqess5tojy2u	172	97	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	98	6	6	CD
work_dbbvwgi6and2fokqess5tojy2u	172	99	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	100	0.32	0.32	CD
work_dbbvwgi6and2fokqess5tojy2u	172	101	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	102	0.06	0.06	CD
work_dbbvwgi6and2fokqess5tojy2u	172	103	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	104	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	172	105	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	106	0.60	0.60	CD
work_dbbvwgi6and2fokqess5tojy2u	172	107	Step	step	NN
work_dbbvwgi6and2fokqess5tojy2u	172	108	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	172	109	passive	passive	JJ
work_dbbvwgi6and2fokqess5tojy2u	172	110	avoidance	avoidance	NN
work_dbbvwgi6and2fokqess5tojy2u	172	111	test	test	NN
work_dbbvwgi6and2fokqess5tojy2u	172	112	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	113	Latency	Latency	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	114	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	115	STM	STM	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	116	2.92	2.92	CD
work_dbbvwgi6and2fokqess5tojy2u	172	117	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	118	0.24	0.24	CD
work_dbbvwgi6and2fokqess5tojy2u	172	119	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	120	6	6	CD
work_dbbvwgi6and2fokqess5tojy2u	172	121	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	122	2.21	2.21	CD
work_dbbvwgi6and2fokqess5tojy2u	172	123	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	124	0.37	0.37	CD
work_dbbvwgi6and2fokqess5tojy2u	172	125	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	126	15	15	CD
work_dbbvwgi6and2fokqess5tojy2u	172	127	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	128	0.12	0.12	CD
work_dbbvwgi6and2fokqess5tojy2u	172	129	LTM	LTM	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	130	2.84	2.84	CD
work_dbbvwgi6and2fokqess5tojy2u	172	131	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	132	0.31	0.31	CD
work_dbbvwgi6and2fokqess5tojy2u	172	133	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	134	7	7	CD
work_dbbvwgi6and2fokqess5tojy2u	172	135	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	136	3.04	3.04	CD
work_dbbvwgi6and2fokqess5tojy2u	172	137	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	138	0.32	0.32	CD
work_dbbvwgi6and2fokqess5tojy2u	172	139	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	140	19	19	CD
work_dbbvwgi6and2fokqess5tojy2u	172	141	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	142	0.66	0.66	CD
work_dbbvwgi6and2fokqess5tojy2u	172	143	Motor	Motor	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	144	function	function	NN
work_dbbvwgi6and2fokqess5tojy2u	172	145	Open	open	JJ
work_dbbvwgi6and2fokqess5tojy2u	172	146	field	field	NN
work_dbbvwgi6and2fokqess5tojy2u	172	147	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	148	total	total	JJ
work_dbbvwgi6and2fokqess5tojy2u	172	149	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	172	150	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	151	1649	1649	CD
work_dbbvwgi6and2fokqess5tojy2u	172	152	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	153	108	108	CD
work_dbbvwgi6and2fokqess5tojy2u	172	154	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	155	8)	8)	CD
work_dbbvwgi6and2fokqess5tojy2u	172	156	1612	1612	CD
work_dbbvwgi6and2fokqess5tojy2u	172	157	±	±	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	158	199	199	CD
work_dbbvwgi6and2fokqess5tojy2u	172	159	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	160	16	16	CD
work_dbbvwgi6and2fokqess5tojy2u	172	161	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	162	0.87	0.87	CD
work_dbbvwgi6and2fokqess5tojy2u	172	163	Rotarod	Rotarod	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	164	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	165	#	#	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	166	Falls	Falls	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	167	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	168	1.14	1.14	CD
work_dbbvwgi6and2fokqess5tojy2u	172	169	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	170	0.46	0.46	CD
work_dbbvwgi6and2fokqess5tojy2u	172	171	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	172	7	7	CD
work_dbbvwgi6and2fokqess5tojy2u	172	173	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	174	4.21	4.21	CD
work_dbbvwgi6and2fokqess5tojy2u	172	175	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	176	0.90	0.90	CD
work_dbbvwgi6and2fokqess5tojy2u	172	177	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	178	19	19	CD
work_dbbvwgi6and2fokqess5tojy2u	172	179	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	180	*	*	NFP
work_dbbvwgi6and2fokqess5tojy2u	172	181	*	*	NFP
work_dbbvwgi6and2fokqess5tojy2u	172	182	0.0058	0.0058	CD
work_dbbvwgi6and2fokqess5tojy2u	172	183	Forelimb	Forelimb	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	184	Grip	Grip	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	185	strength	strength	NN
work_dbbvwgi6and2fokqess5tojy2u	172	186	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	187	s	s	NN
work_dbbvwgi6and2fokqess5tojy2u	172	188	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	189	7.00	7.00	CD
work_dbbvwgi6and2fokqess5tojy2u	172	190	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	191	0.98	0.98	CD
work_dbbvwgi6and2fokqess5tojy2u	172	192	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	193	6	6	CD
work_dbbvwgi6and2fokqess5tojy2u	172	194	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	172	195	7.96	7.96	CD
work_dbbvwgi6and2fokqess5tojy2u	172	196	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	172	197	0.78	0.78	CD
work_dbbvwgi6and2fokqess5tojy2u	172	198	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	199	8)	8)	CD
work_dbbvwgi6and2fokqess5tojy2u	172	200	0.46	0.46	CD
work_dbbvwgi6and2fokqess5tojy2u	172	201	STM	STM	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	202	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	172	203	Short	Short	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	204	Term	Term	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	205	Memory	Memory	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	206	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	172	207	LTM	LTM	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	208	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	172	209	Long	Long	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	210	Term	Term	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	211	Memory	Memory	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	212	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	172	213	DI	DI	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	214	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	172	215	Discrimination	discrimination	NN
work_dbbvwgi6and2fokqess5tojy2u	172	216	index	index	NN
work_dbbvwgi6and2fokqess5tojy2u	172	217	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	172	218	n	n	NN
work_dbbvwgi6and2fokqess5tojy2u	172	219	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	172	220	number	number	NN
work_dbbvwgi6and2fokqess5tojy2u	172	221	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	172	222	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	172	223	Oncotarget56091www.impactjournals.com/oncotarget	Oncotarget56091www.impactjournals.com/oncotarget	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	172	224	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	172	225	6	6	CD
work_dbbvwgi6and2fokqess5tojy2u	172	226	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	172	227	A	a	DT
work_dbbvwgi6and2fokqess5tojy2u	172	228	homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	172	229	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	172	230	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	172	231	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	172	232	HERC2	herc2	NN
work_dbbvwgi6and2fokqess5tojy2u	172	233	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	172	234	causes	cause	VBZ
work_dbbvwgi6and2fokqess5tojy2u	172	235	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	172	236	Angelman	Angelman	NNP
work_dbbvwgi6and2fokqess5tojy2u	172	237	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	172	238	like	like	JJ
work_dbbvwgi6and2fokqess5tojy2u	172	239	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	172	240	reduces	reduce	VBZ
work_dbbvwgi6and2fokqess5tojy2u	172	241	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	172	242	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	172	243	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	172	244	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	172	245	HErc2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	172	246	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	172	247	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	173	1	A.	A.	NNP
work_dbbvwgi6and2fokqess5tojy2u	173	2	Fibroblasts	fibroblast	NNS
work_dbbvwgi6and2fokqess5tojy2u	173	3	derived	derive	VBN
work_dbbvwgi6and2fokqess5tojy2u	173	4	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	173	5	individuals	individual	NNS
work_dbbvwgi6and2fokqess5tojy2u	173	6	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	173	7	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	173	8	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	173	9	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	173	10	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	173	11	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	173	12	HERC2	herc2	NN
work_dbbvwgi6and2fokqess5tojy2u	173	13	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	173	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	173	15	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	173	16	P594L	P594L	NNP
work_dbbvwgi6and2fokqess5tojy2u	173	17	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	173	18	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	173	19	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	173	20	immunoblotting	immunoblotte	VBG
work_dbbvwgi6and2fokqess5tojy2u	173	21	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	173	22	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	173	23	indicated	indicate	VBN
work_dbbvwgi6and2fokqess5tojy2u	173	24	antibodies	antibody	NNS
work_dbbvwgi6and2fokqess5tojy2u	173	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	174	1	Levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	174	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	174	3	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	174	4	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	174	5	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	174	6	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	174	7	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	174	8	quantified	quantify	VBN
work_dbbvwgi6and2fokqess5tojy2u	174	9	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	174	10	normalized	normalize	VBN
work_dbbvwgi6and2fokqess5tojy2u	174	11	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	174	12	respect	respect	NN
work_dbbvwgi6and2fokqess5tojy2u	174	13	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	174	14	α	α	JJ
work_dbbvwgi6and2fokqess5tojy2u	174	15	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	174	16	tubulin	tubulin	JJ
work_dbbvwgi6and2fokqess5tojy2u	174	17	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	174	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	175	1	b.	b.	NNP
work_dbbvwgi6and2fokqess5tojy2u	176	1	Levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	176	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	176	3	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	176	4	mRNA	mRNA	NNS
work_dbbvwgi6and2fokqess5tojy2u	176	5	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	176	6	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	176	7	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	176	8	RT	RT	NNP
work_dbbvwgi6and2fokqess5tojy2u	176	9	quantitative	quantitative	JJ
work_dbbvwgi6and2fokqess5tojy2u	176	10	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	176	11	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	176	12	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	176	13	normalized	normalize	VBD
work_dbbvwgi6and2fokqess5tojy2u	176	14	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	176	15	respect	respect	NN
work_dbbvwgi6and2fokqess5tojy2u	176	16	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	176	17	18S	18s	CD
work_dbbvwgi6and2fokqess5tojy2u	176	18	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	176	19	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	176	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	177	1	c.	c.	NN
work_dbbvwgi6and2fokqess5tojy2u	177	2	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	177	3	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	177	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	177	5	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	177	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	177	7	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	177	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	177	9	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	177	10	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	177	11	α	α	NNP
work_dbbvwgi6and2fokqess5tojy2u	177	12	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	177	13	tubulin	tubulin	NN
work_dbbvwgi6and2fokqess5tojy2u	177	14	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	177	15	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	177	16	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	177	17	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	177	18	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	177	19	presence	presence	NN
work_dbbvwgi6and2fokqess5tojy2u	177	20	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	177	21	absence	absence	NN
work_dbbvwgi6and2fokqess5tojy2u	177	22	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	177	23	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	177	24	proteasome	proteasome	JJ
work_dbbvwgi6and2fokqess5tojy2u	177	25	inhibitor	inhibitor	NN
work_dbbvwgi6and2fokqess5tojy2u	177	26	MG132	mg132	NN
work_dbbvwgi6and2fokqess5tojy2u	177	27	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	178	1	D.	D.	NNP
work_dbbvwgi6and2fokqess5tojy2u	178	2	U2OS	U2OS	NNP
work_dbbvwgi6and2fokqess5tojy2u	178	3	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	178	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	178	5	transfected	transfecte	VBN
work_dbbvwgi6and2fokqess5tojy2u	178	6	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	178	7	non	non	JJ
work_dbbvwgi6and2fokqess5tojy2u	178	8	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	178	9	targeting	targeting	JJ
work_dbbvwgi6and2fokqess5tojy2u	178	10	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	178	11	NT	NT	NNP
work_dbbvwgi6and2fokqess5tojy2u	178	12	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	178	13	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	178	14	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	178	15	siRNAs	siRNAs	NNP
work_dbbvwgi6and2fokqess5tojy2u	178	16	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	178	17	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	178	18	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	178	19	immunoblotting	immunoblotte	VBG
work_dbbvwgi6and2fokqess5tojy2u	178	20	against	against	IN
work_dbbvwgi6and2fokqess5tojy2u	178	21	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	178	22	indicated	indicate	VBN
work_dbbvwgi6and2fokqess5tojy2u	178	23	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	178	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	179	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	179	2	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	179	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	179	4	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	179	5	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	179	6	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	179	7	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	179	8	quantified	quantify	VBN
work_dbbvwgi6and2fokqess5tojy2u	179	9	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	179	10	normalized	normalize	VBN
work_dbbvwgi6and2fokqess5tojy2u	179	11	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	179	12	respect	respect	NN
work_dbbvwgi6and2fokqess5tojy2u	179	13	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	179	14	Ran	Ran	NNP
work_dbbvwgi6and2fokqess5tojy2u	179	15	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	179	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	180	1	Oncotarget56092www.impactjournals.com/oncotarget	oncotarget56092www.impactjournals.com/oncotarget	ADD
work_dbbvwgi6and2fokqess5tojy2u	180	2	HErc2	HErc2	NNP
work_dbbvwgi6and2fokqess5tojy2u	180	3	regulates	regulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	180	4	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	180	5	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	180	6	Individuals	Individuals	NNPS
work_dbbvwgi6and2fokqess5tojy2u	180	7	carrying	carry	VBG
work_dbbvwgi6and2fokqess5tojy2u	180	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	180	9	HERC2P594L	HERC2P594L	NNP
work_dbbvwgi6and2fokqess5tojy2u	180	10	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	180	11	present	present	JJ
work_dbbvwgi6and2fokqess5tojy2u	180	12	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	180	13	severe	severe	JJ
work_dbbvwgi6and2fokqess5tojy2u	180	14	developmental	developmental	JJ
work_dbbvwgi6and2fokqess5tojy2u	180	15	delay	delay	NN
work_dbbvwgi6and2fokqess5tojy2u	180	16	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	180	17	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	180	18	unstable	unstable	JJ
work_dbbvwgi6and2fokqess5tojy2u	180	19	gait	gait	NN
work_dbbvwgi6and2fokqess5tojy2u	180	20	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	180	21	4,5	4,5	CD
work_dbbvwgi6and2fokqess5tojy2u	180	22	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	180	23	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	181	1	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	181	2	wondered	wonder	VBD
work_dbbvwgi6and2fokqess5tojy2u	181	3	whether	whether	IN
work_dbbvwgi6and2fokqess5tojy2u	181	4	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	181	5	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	181	6	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	181	7	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	181	8	reduction	reduction	NN
work_dbbvwgi6and2fokqess5tojy2u	181	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	181	10	approximately	approximately	RB
work_dbbvwgi6and2fokqess5tojy2u	181	11	50	50	CD
work_dbbvwgi6and2fokqess5tojy2u	181	12	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	181	13	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	181	14	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	181	15	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	181	16	could	could	MD
work_dbbvwgi6and2fokqess5tojy2u	181	17	have	have	VB
work_dbbvwgi6and2fokqess5tojy2u	181	18	some	some	DT
work_dbbvwgi6and2fokqess5tojy2u	181	19	features	feature	NNS
work_dbbvwgi6and2fokqess5tojy2u	181	20	found	find	VBN
work_dbbvwgi6and2fokqess5tojy2u	181	21	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	181	22	HERC2P594L	HERC2P594L	NNP
work_dbbvwgi6and2fokqess5tojy2u	181	23	patients	patient	NNS
work_dbbvwgi6and2fokqess5tojy2u	181	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	182	1	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	182	2	examine	examine	VB
work_dbbvwgi6and2fokqess5tojy2u	182	3	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	182	4	question	question	NN
work_dbbvwgi6and2fokqess5tojy2u	182	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	182	6	behavioural	behavioural	JJ
work_dbbvwgi6and2fokqess5tojy2u	182	7	tests	test	NNS
work_dbbvwgi6and2fokqess5tojy2u	182	8	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	182	9	measure	measure	VB
work_dbbvwgi6and2fokqess5tojy2u	182	10	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	182	11	cognitive	cognitive	JJ
work_dbbvwgi6and2fokqess5tojy2u	182	12	tasks	task	NNS
work_dbbvwgi6and2fokqess5tojy2u	182	13	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	182	14	performed	perform	VBN
work_dbbvwgi6and2fokqess5tojy2u	182	15	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	182	16	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	182	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	182	18	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	182	19	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	182	20	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	182	21	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	182	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	183	1	Except	except	IN
work_dbbvwgi6and2fokqess5tojy2u	183	2	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	183	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	183	4	rotarod	rotarod	NN
work_dbbvwgi6and2fokqess5tojy2u	183	5	test	test	NN
work_dbbvwgi6and2fokqess5tojy2u	183	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	183	7	no	no	DT
work_dbbvwgi6and2fokqess5tojy2u	183	8	significant	significant	JJ
work_dbbvwgi6and2fokqess5tojy2u	183	9	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	183	10	7	7	CD
work_dbbvwgi6and2fokqess5tojy2u	183	11	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	183	12	Impaired	impaired	JJ
work_dbbvwgi6and2fokqess5tojy2u	183	13	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	183	14	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	183	15	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	183	16	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	183	17	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	183	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	184	1	A.-b	a.-b	XX
work_dbbvwgi6and2fokqess5tojy2u	184	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	185	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	185	2	number	number	NN
work_dbbvwgi6and2fokqess5tojy2u	185	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	185	4	falls	fall	NNS
work_dbbvwgi6and2fokqess5tojy2u	185	5	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	185	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	185	7	rotarod	rotarod	NNP
work_dbbvwgi6and2fokqess5tojy2u	185	8	increases	increase	NNS
work_dbbvwgi6and2fokqess5tojy2u	185	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	185	10	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	185	11	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	185	12	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	185	13	6	6	CD
work_dbbvwgi6and2fokqess5tojy2u	185	14	months	month	NNS
work_dbbvwgi6and2fokqess5tojy2u	185	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	185	16	age	age	NN
work_dbbvwgi6and2fokqess5tojy2u	185	17	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	185	18	comparison	comparison	NN
work_dbbvwgi6and2fokqess5tojy2u	185	19	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	185	20	control	control	NN
work_dbbvwgi6and2fokqess5tojy2u	185	21	littermates	littermate	NNS
work_dbbvwgi6and2fokqess5tojy2u	185	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	186	1	c.	c.	NN
work_dbbvwgi6and2fokqess5tojy2u	186	2	No	no	DT
work_dbbvwgi6and2fokqess5tojy2u	186	3	difference	difference	NN
work_dbbvwgi6and2fokqess5tojy2u	186	4	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	186	5	found	find	VBN
work_dbbvwgi6and2fokqess5tojy2u	186	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	186	7	p53+/-	p53+/-	NNP
work_dbbvwgi6and2fokqess5tojy2u	186	8	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	186	9	p53-/-	p53-/-	NNP
work_dbbvwgi6and2fokqess5tojy2u	186	10	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	186	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	186	12	comparison	comparison	NN
work_dbbvwgi6and2fokqess5tojy2u	186	13	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	186	14	WT	WT	NNP
work_dbbvwgi6and2fokqess5tojy2u	186	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	187	1	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	187	2	D	D	NNP
work_dbbvwgi6and2fokqess5tojy2u	187	3	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	187	4	E	e	NN
work_dbbvwgi6and2fokqess5tojy2u	187	5	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	187	6	EMG	emg	NN
work_dbbvwgi6and2fokqess5tojy2u	187	7	measurements	measurement	NNS
work_dbbvwgi6and2fokqess5tojy2u	187	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	187	9	CMAP	CMAP	NNP
work_dbbvwgi6and2fokqess5tojy2u	187	10	amplitudes	amplitude	NNS
work_dbbvwgi6and2fokqess5tojy2u	187	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	187	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	187	13	MG	MG	NNP
work_dbbvwgi6and2fokqess5tojy2u	187	14	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	187	15	control	control	NN
work_dbbvwgi6and2fokqess5tojy2u	187	16	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	187	17	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	187	18	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	187	19	show	show	VBP
work_dbbvwgi6and2fokqess5tojy2u	187	20	normal	normal	JJ
work_dbbvwgi6and2fokqess5tojy2u	187	21	neurotransmission	neurotransmission	NN
work_dbbvwgi6and2fokqess5tojy2u	187	22	efficacy	efficacy	NN
work_dbbvwgi6and2fokqess5tojy2u	187	23	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	187	24	postnatal	postnatal	JJ
work_dbbvwgi6and2fokqess5tojy2u	187	25	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	187	26	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	187	27	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	188	1	D.	D.	NNP
work_dbbvwgi6and2fokqess5tojy2u	188	2	Representative	Representative	NNP
work_dbbvwgi6and2fokqess5tojy2u	188	3	recordings	recording	VBZ
work_dbbvwgi6and2fokqess5tojy2u	188	4	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	188	5	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	188	6	train	train	NN
work_dbbvwgi6and2fokqess5tojy2u	188	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	188	8	stimuli	stimulus	NNS
work_dbbvwgi6and2fokqess5tojy2u	188	9	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	188	10	100	100	CD
work_dbbvwgi6and2fokqess5tojy2u	188	11	Hz	Hz	NNS
work_dbbvwgi6and2fokqess5tojy2u	188	12	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	188	13	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	188	14	control	control	NN
work_dbbvwgi6and2fokqess5tojy2u	188	15	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	188	16	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	188	17	Herc2+/530mouse	herc2+/530mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	188	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	189	1	E.	E.	NNP
work_dbbvwgi6and2fokqess5tojy2u	189	2	Depression	Depression	NNP
work_dbbvwgi6and2fokqess5tojy2u	189	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	189	4	CMAP	CMAP	NNP
work_dbbvwgi6and2fokqess5tojy2u	189	5	amplitudes	amplitude	NNS
work_dbbvwgi6and2fokqess5tojy2u	189	6	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	189	7	normalized	normalized	JJ
work_dbbvwgi6and2fokqess5tojy2u	189	8	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	189	9	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	189	10	first	first	JJ
work_dbbvwgi6and2fokqess5tojy2u	189	11	response	response	NN
work_dbbvwgi6and2fokqess5tojy2u	189	12	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	189	13	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	189	14	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	189	15	train	train	NN
work_dbbvwgi6and2fokqess5tojy2u	189	16	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	189	17	stimuli	stimulus	NNS
work_dbbvwgi6and2fokqess5tojy2u	189	18	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	189	19	300	300	CD
work_dbbvwgi6and2fokqess5tojy2u	189	20	ms	m	NNS
work_dbbvwgi6and2fokqess5tojy2u	189	21	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	189	22	100	100	CD
work_dbbvwgi6and2fokqess5tojy2u	189	23	Hz	Hz	NNP
work_dbbvwgi6and2fokqess5tojy2u	189	24	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	189	25	control	control	NN
work_dbbvwgi6and2fokqess5tojy2u	189	26	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	189	27	n	n	NN
work_dbbvwgi6and2fokqess5tojy2u	189	28	=	=	SYM
work_dbbvwgi6and2fokqess5tojy2u	189	29	7	7	CD
work_dbbvwgi6and2fokqess5tojy2u	189	30	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	189	31	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	189	32	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	189	33	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	189	34	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	189	35	n	n	CC
work_dbbvwgi6and2fokqess5tojy2u	189	36	=	=	SYM
work_dbbvwgi6and2fokqess5tojy2u	189	37	18	18	CD
work_dbbvwgi6and2fokqess5tojy2u	189	38	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	189	39	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	190	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	190	2	train	train	NN
work_dbbvwgi6and2fokqess5tojy2u	190	3	index	index	NN
work_dbbvwgi6and2fokqess5tojy2u	190	4	F.	F.	NNP
work_dbbvwgi6and2fokqess5tojy2u	190	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	190	6	corresponding	correspond	VBG
work_dbbvwgi6and2fokqess5tojy2u	190	7	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	190	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	190	9	depression	depression	NN
work_dbbvwgi6and2fokqess5tojy2u	190	10	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	190	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	190	12	end	end	NN
work_dbbvwgi6and2fokqess5tojy2u	190	13	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	190	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	190	15	train	train	NN
work_dbbvwgi6and2fokqess5tojy2u	190	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	190	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	190	18	PPF	PPF	NNP
work_dbbvwgi6and2fokqess5tojy2u	190	19	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	190	20	Pair	Pair	NNP
work_dbbvwgi6and2fokqess5tojy2u	190	21	-Pulse	-Pulse	HYPH
work_dbbvwgi6and2fokqess5tojy2u	190	22	Facilitation	Facilitation	NNP
work_dbbvwgi6and2fokqess5tojy2u	190	23	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	190	24	G.	G.	NNP
work_dbbvwgi6and2fokqess5tojy2u	190	25	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	190	26	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	190	27	similar	similar	JJ
work_dbbvwgi6and2fokqess5tojy2u	190	28	between	between	IN
work_dbbvwgi6and2fokqess5tojy2u	190	29	groups	group	NNS
work_dbbvwgi6and2fokqess5tojy2u	190	30	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	191	1	Oncotarget56093www.impactjournals.com/oncotarget	Oncotarget56093www.impactjournals.com/oncotarget	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	191	2	differences	difference	NNS
work_dbbvwgi6and2fokqess5tojy2u	191	3	between	between	IN
work_dbbvwgi6and2fokqess5tojy2u	191	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	191	5	two	two	CD
work_dbbvwgi6and2fokqess5tojy2u	191	6	groups	group	NNS
work_dbbvwgi6and2fokqess5tojy2u	191	7	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	191	8	found	find	VBN
work_dbbvwgi6and2fokqess5tojy2u	191	9	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	191	10	Table	table	NN
work_dbbvwgi6and2fokqess5tojy2u	191	11	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	191	12	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	191	13	Supplementary	Supplementary	NNP
work_dbbvwgi6and2fokqess5tojy2u	191	14	Video	Video	NNP
work_dbbvwgi6and2fokqess5tojy2u	191	15	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	191	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	192	1	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	192	2	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	192	3	displayed	display	VBD
work_dbbvwgi6and2fokqess5tojy2u	192	4	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	192	5	statistically	statistically	RB
work_dbbvwgi6and2fokqess5tojy2u	192	6	significant	significant	JJ
work_dbbvwgi6and2fokqess5tojy2u	192	7	increase	increase	NN
work_dbbvwgi6and2fokqess5tojy2u	192	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	192	9	rotarod	rotarod	NNP
work_dbbvwgi6and2fokqess5tojy2u	192	10	falls	fall	VBZ
work_dbbvwgi6and2fokqess5tojy2u	192	11	compared	compare	VBN
work_dbbvwgi6and2fokqess5tojy2u	192	12	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	192	13	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	192	14	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	192	15	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	192	16	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	192	17	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	192	18	Herc2+/+	herc2+/+	NN
work_dbbvwgi6and2fokqess5tojy2u	192	19	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	192	20	1.14	1.14	CD
work_dbbvwgi6and2fokqess5tojy2u	192	21	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	192	22	0.46	0.46	CD
work_dbbvwgi6and2fokqess5tojy2u	192	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	192	24	n	n	NN
work_dbbvwgi6and2fokqess5tojy2u	192	25	=	=	SYM
work_dbbvwgi6and2fokqess5tojy2u	192	26	7	7	CD
work_dbbvwgi6and2fokqess5tojy2u	192	27	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	192	28	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	192	29	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	192	30	4.21	4.21	CD
work_dbbvwgi6and2fokqess5tojy2u	192	31	±	±	CD
work_dbbvwgi6and2fokqess5tojy2u	192	32	0.90	0.90	CD
work_dbbvwgi6and2fokqess5tojy2u	192	33	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	192	34	n	n	NNP
work_dbbvwgi6and2fokqess5tojy2u	192	35	=	=	SYM
work_dbbvwgi6and2fokqess5tojy2u	192	36	19	19	CD
work_dbbvwgi6and2fokqess5tojy2u	192	37	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	192	38	p	p	NNP
work_dbbvwgi6and2fokqess5tojy2u	192	39	=	=	SYM
work_dbbvwgi6and2fokqess5tojy2u	192	40	0.0058	0.0058	CD
work_dbbvwgi6and2fokqess5tojy2u	192	41	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	192	42	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	192	43	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	192	44	7A-	7a-	CD
work_dbbvwgi6and2fokqess5tojy2u	192	45	7B	7b	NN
work_dbbvwgi6and2fokqess5tojy2u	192	46	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	192	47	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	192	48	suggesting	suggest	VBG
work_dbbvwgi6and2fokqess5tojy2u	192	49	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	192	50	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	192	51	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	192	52	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	192	53	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	192	54	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	192	55	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	192	56	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	193	1	Because	because	IN
work_dbbvwgi6and2fokqess5tojy2u	193	2	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	193	3	regulates	regulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	193	4	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	193	5	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	193	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	193	7	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	193	8	asked	ask	VBD
work_dbbvwgi6and2fokqess5tojy2u	193	9	whether	whether	IN
work_dbbvwgi6and2fokqess5tojy2u	193	10	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	193	11	inactivation	inactivation	NN
work_dbbvwgi6and2fokqess5tojy2u	193	12	could	could	MD
work_dbbvwgi6and2fokqess5tojy2u	193	13	produce	produce	VB
work_dbbvwgi6and2fokqess5tojy2u	193	14	effects	effect	NNS
work_dbbvwgi6and2fokqess5tojy2u	193	15	similar	similar	JJ
work_dbbvwgi6and2fokqess5tojy2u	193	16	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	193	17	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	193	18	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	193	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	194	1	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	194	2	performed	perform	VBD
work_dbbvwgi6and2fokqess5tojy2u	194	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	194	4	rotarod	rotarod	NN
work_dbbvwgi6and2fokqess5tojy2u	194	5	test	test	NN
work_dbbvwgi6and2fokqess5tojy2u	194	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	194	7	p53+/-	p53+/-	NNP
work_dbbvwgi6and2fokqess5tojy2u	194	8	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	194	9	p53-/-	p53-/-	NNP
work_dbbvwgi6and2fokqess5tojy2u	194	10	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	194	11	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	195	1	No	no	DT
work_dbbvwgi6and2fokqess5tojy2u	195	2	significant	significant	JJ
work_dbbvwgi6and2fokqess5tojy2u	195	3	differences	difference	NNS
work_dbbvwgi6and2fokqess5tojy2u	195	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	195	5	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	195	6	compared	compare	VBN
work_dbbvwgi6and2fokqess5tojy2u	195	7	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	195	8	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	195	9	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	195	10	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	195	11	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	195	12	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	195	13	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	195	14	7C	7c	NN
work_dbbvwgi6and2fokqess5tojy2u	195	15	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	195	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	196	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	196	2	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	196	3	indicate	indicate	VBP
work_dbbvwgi6and2fokqess5tojy2u	196	4	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	196	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	196	6	impaired	impaired	JJ
work_dbbvwgi6and2fokqess5tojy2u	196	7	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	196	8	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	196	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	196	10	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	196	11	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	196	12	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	196	13	specific	specific	JJ
work_dbbvwgi6and2fokqess5tojy2u	196	14	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	196	15	independent	independent	JJ
work_dbbvwgi6and2fokqess5tojy2u	196	16	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	196	17	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	196	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	197	1	Next	next	RB
work_dbbvwgi6and2fokqess5tojy2u	197	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	197	3	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	197	4	analyzed	analyze	VBD
work_dbbvwgi6and2fokqess5tojy2u	197	5	whether	whether	IN
work_dbbvwgi6and2fokqess5tojy2u	197	6	muscular	muscular	JJ
work_dbbvwgi6and2fokqess5tojy2u	197	7	function	function	NN
work_dbbvwgi6and2fokqess5tojy2u	197	8	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	197	9	affected	affect	VBN
work_dbbvwgi6and2fokqess5tojy2u	197	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	197	11	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	197	12	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	197	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	198	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	198	2	electrical	electrical	JJ
work_dbbvwgi6and2fokqess5tojy2u	198	3	neuromuscular	neuromuscular	JJ
work_dbbvwgi6and2fokqess5tojy2u	198	4	properties	property	NNS
work_dbbvwgi6and2fokqess5tojy2u	198	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	198	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	198	7	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	198	8	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	198	9	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	198	10	studied	study	VBN
work_dbbvwgi6and2fokqess5tojy2u	198	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	198	12	vivo	vivo	NNP
work_dbbvwgi6and2fokqess5tojy2u	198	13	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	198	14	performing	perform	VBG
work_dbbvwgi6and2fokqess5tojy2u	198	15	electromyography	electromyography	NN
work_dbbvwgi6and2fokqess5tojy2u	198	16	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	198	17	EMG	EMG	NNP
work_dbbvwgi6and2fokqess5tojy2u	198	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	198	19	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	198	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	198	21	medial	medial	JJ
work_dbbvwgi6and2fokqess5tojy2u	198	22	gastrocnemius	gastrocnemius	NN
work_dbbvwgi6and2fokqess5tojy2u	198	23	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	198	24	MG	MG	NNP
work_dbbvwgi6and2fokqess5tojy2u	198	25	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	198	26	muscle	muscle	NN
work_dbbvwgi6and2fokqess5tojy2u	198	27	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	198	28	short	short	JJ
work_dbbvwgi6and2fokqess5tojy2u	198	29	train	train	NN
work_dbbvwgi6and2fokqess5tojy2u	198	30	stimuli	stimulus	NNS
work_dbbvwgi6and2fokqess5tojy2u	198	31	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	198	32	100	100	CD
work_dbbvwgi6and2fokqess5tojy2u	198	33	Hz	Hz	NNP
work_dbbvwgi6and2fokqess5tojy2u	198	34	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	198	35	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	198	36	7D	7d	NN
work_dbbvwgi6and2fokqess5tojy2u	198	37	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	198	38	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	199	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	199	2	depression	depression	NN
work_dbbvwgi6and2fokqess5tojy2u	199	3	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	199	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	199	5	end	end	NN
work_dbbvwgi6and2fokqess5tojy2u	199	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	199	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	199	8	facilitation	facilitation	NN
work_dbbvwgi6and2fokqess5tojy2u	199	9	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	199	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	199	11	beginning	beginning	NN
work_dbbvwgi6and2fokqess5tojy2u	199	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	199	13	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	199	14	train	train	NN
work_dbbvwgi6and2fokqess5tojy2u	199	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	199	16	30	30	CD
work_dbbvwgi6and2fokqess5tojy2u	199	17	stimuli	stimulus	NNS
work_dbbvwgi6and2fokqess5tojy2u	199	18	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	199	19	similar	similar	JJ
work_dbbvwgi6and2fokqess5tojy2u	199	20	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	199	21	mutant	mutant	JJ
work_dbbvwgi6and2fokqess5tojy2u	199	22	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	199	23	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	199	24	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	199	25	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	199	26	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	199	27	when	when	WRB
work_dbbvwgi6and2fokqess5tojy2u	199	28	measured	measure	VBN
work_dbbvwgi6and2fokqess5tojy2u	199	29	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	199	30	normalization	normalization	NN
work_dbbvwgi6and2fokqess5tojy2u	199	31	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	199	32	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	199	33	CMAP	CMAP	NNP
work_dbbvwgi6and2fokqess5tojy2u	199	34	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	199	35	Compound	Compound	NNP
work_dbbvwgi6and2fokqess5tojy2u	199	36	Muscular	Muscular	NNP
work_dbbvwgi6and2fokqess5tojy2u	199	37	Action	Action	NNP
work_dbbvwgi6and2fokqess5tojy2u	199	38	Potentials	Potentials	NNPS
work_dbbvwgi6and2fokqess5tojy2u	199	39	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	199	40	amplitude	amplitude	NN
work_dbbvwgi6and2fokqess5tojy2u	199	41	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	199	42	p	p	NN
work_dbbvwgi6and2fokqess5tojy2u	199	43	=	=	SYM
work_dbbvwgi6and2fokqess5tojy2u	199	44	0.8	0.8	CD
work_dbbvwgi6and2fokqess5tojy2u	199	45	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	199	46	p	p	NN
work_dbbvwgi6and2fokqess5tojy2u	199	47	=	=	SYM
work_dbbvwgi6and2fokqess5tojy2u	199	48	0.85	0.85	CD
work_dbbvwgi6and2fokqess5tojy2u	199	49	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	199	50	respectively	respectively	RB
work_dbbvwgi6and2fokqess5tojy2u	199	51	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	199	52	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	199	53	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	199	54	7E-7	7E-7	NNP
work_dbbvwgi6and2fokqess5tojy2u	199	55	G	G	NNP
work_dbbvwgi6and2fokqess5tojy2u	199	56	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	199	57	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	200	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	200	2	results	result	NNS
work_dbbvwgi6and2fokqess5tojy2u	200	3	indicate	indicate	VBP
work_dbbvwgi6and2fokqess5tojy2u	200	4	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	200	5	normal	normal	JJ
work_dbbvwgi6and2fokqess5tojy2u	200	6	muscular	muscular	JJ
work_dbbvwgi6and2fokqess5tojy2u	200	7	function	function	NN
work_dbbvwgi6and2fokqess5tojy2u	200	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	201	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	201	2	cerebellum	cerebellum	NN
work_dbbvwgi6and2fokqess5tojy2u	201	3	regulates	regulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	201	4	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	201	5	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	201	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	201	7	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	201	8	alterations	alteration	NNS
work_dbbvwgi6and2fokqess5tojy2u	201	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	201	10	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	201	11	structure	structure	NN
work_dbbvwgi6and2fokqess5tojy2u	201	12	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	201	13	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	201	14	associated	associate	VBN
work_dbbvwgi6and2fokqess5tojy2u	201	15	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	201	16	impaired	impaired	JJ
work_dbbvwgi6and2fokqess5tojy2u	201	17	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	201	18	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	201	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	202	1	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	202	2	examine	examine	VB
work_dbbvwgi6and2fokqess5tojy2u	202	3	whether	whether	IN
work_dbbvwgi6and2fokqess5tojy2u	202	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	202	5	deficit	deficit	NN
work_dbbvwgi6and2fokqess5tojy2u	202	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	202	7	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	202	8	synchronization	synchronization	NN
work_dbbvwgi6and2fokqess5tojy2u	202	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	202	10	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	202	11	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	202	12	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	202	13	caused	cause	VBN
work_dbbvwgi6and2fokqess5tojy2u	202	14	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	202	15	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	202	16	alteration	alteration	NN
work_dbbvwgi6and2fokqess5tojy2u	202	17	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	202	18	cerebellar	cerebellar	JJ
work_dbbvwgi6and2fokqess5tojy2u	202	19	structure	structure	NN
work_dbbvwgi6and2fokqess5tojy2u	202	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	202	21	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	202	22	performed	perform	VBD
work_dbbvwgi6and2fokqess5tojy2u	202	23	immunohistochemistry	immunohistochemistry	NN
work_dbbvwgi6and2fokqess5tojy2u	202	24	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	202	25	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	202	26	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	202	27	specific	specific	JJ
work_dbbvwgi6and2fokqess5tojy2u	202	28	marker	marker	NN
work_dbbvwgi6and2fokqess5tojy2u	202	29	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	202	30	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	202	31	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	202	32	calbindin	calbindin	NN
work_dbbvwgi6and2fokqess5tojy2u	202	33	-	-	:
work_dbbvwgi6and2fokqess5tojy2u	202	34	D28	D28	NNP
work_dbbvwgi6and2fokqess5tojy2u	202	35	k	k	NN
work_dbbvwgi6and2fokqess5tojy2u	202	36	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	202	37	CaBP	cabp	NN
work_dbbvwgi6and2fokqess5tojy2u	202	38	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	202	39	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	202	40	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	202	41	8)	8)	CD
work_dbbvwgi6and2fokqess5tojy2u	202	42	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	203	1	CaBP	CaBP	NNP
work_dbbvwgi6and2fokqess5tojy2u	203	2	immunoreactive	immunoreactive	JJ
work_dbbvwgi6and2fokqess5tojy2u	203	3	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	203	4	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	203	5	somata	somata	NN
work_dbbvwgi6and2fokqess5tojy2u	203	6	form	form	VBP
work_dbbvwgi6and2fokqess5tojy2u	203	7	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	203	8	continuous	continuous	JJ
work_dbbvwgi6and2fokqess5tojy2u	203	9	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	203	10	layer	layer	NN
work_dbbvwgi6and2fokqess5tojy2u	203	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	203	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	203	13	cerebellar	cerebellar	JJ
work_dbbvwgi6and2fokqess5tojy2u	203	14	cortex	cortex	NN
work_dbbvwgi6and2fokqess5tojy2u	203	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	203	16	Herc2+/+	Herc2+/+	NNP
work_dbbvwgi6and2fokqess5tojy2u	203	17	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	203	18	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	203	19	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	203	20	8A-8C	8a-8c	CD
work_dbbvwgi6and2fokqess5tojy2u	203	21	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	203	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	204	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	204	2	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	204	3	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	204	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	204	5	parasagittal	parasagittal	JJ
work_dbbvwgi6and2fokqess5tojy2u	204	6	zones	zone	NNS
work_dbbvwgi6and2fokqess5tojy2u	204	7	devoid	devoid	JJ
work_dbbvwgi6and2fokqess5tojy2u	204	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	204	9	immunoreactivity	immunoreactivity	NN
work_dbbvwgi6and2fokqess5tojy2u	204	10	throughout	throughout	IN
work_dbbvwgi6and2fokqess5tojy2u	204	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	204	12	cerebellum	cerebellum	NN
work_dbbvwgi6and2fokqess5tojy2u	204	13	indicative	indicative	JJ
work_dbbvwgi6and2fokqess5tojy2u	204	14	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	204	15	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	204	16	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	204	17	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	204	18	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	204	19	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	204	20	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	204	21	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	204	22	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	204	23	arrowheads	arrowhead	NNS
work_dbbvwgi6and2fokqess5tojy2u	204	24	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	204	25	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	204	26	8D-8F	8d-8f	CD
work_dbbvwgi6and2fokqess5tojy2u	204	27	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	204	28	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	205	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	205	2	symmetrical	symmetrical	JJ
work_dbbvwgi6and2fokqess5tojy2u	205	3	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	205	4	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	205	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	205	6	deprived	deprive	VBN
work_dbbvwgi6and2fokqess5tojy2u	205	7	bands	band	NNS
work_dbbvwgi6and2fokqess5tojy2u	205	8	-characterized	-characterize	VBN
work_dbbvwgi6and2fokqess5tojy2u	205	9	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	205	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	205	11	presence	presence	NN
work_dbbvwgi6and2fokqess5tojy2u	205	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	205	13	wide	wide	JJ
work_dbbvwgi6and2fokqess5tojy2u	205	14	spaces	space	NNS
work_dbbvwgi6and2fokqess5tojy2u	205	15	lacking	lack	VBG
work_dbbvwgi6and2fokqess5tojy2u	205	16	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	205	17	somata	somata	NN
work_dbbvwgi6and2fokqess5tojy2u	205	18	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	205	19	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	205	20	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	205	21	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	205	22	layer	layer	NN
work_dbbvwgi6and2fokqess5tojy2u	205	23	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	205	24	asterisks	asterisk	NNS
work_dbbvwgi6and2fokqess5tojy2u	205	25	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	205	26	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	205	27	8H	8h	NN
work_dbbvwgi6and2fokqess5tojy2u	205	28	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	205	29	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	205	30	dendritic	dendritic	JJ
work_dbbvwgi6and2fokqess5tojy2u	205	31	debris	debris	NN
work_dbbvwgi6and2fokqess5tojy2u	205	32	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	205	33	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	205	34	molecular	molecular	JJ
work_dbbvwgi6and2fokqess5tojy2u	205	35	layer	layer	NN
work_dbbvwgi6and2fokqess5tojy2u	205	36	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	205	37	mol	mol	NN
work_dbbvwgi6and2fokqess5tojy2u	205	38	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	205	39	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	205	40	8H)-	8h)-	CD
work_dbbvwgi6and2fokqess5tojy2u	205	41	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	205	42	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	205	43	distributed	distribute	VBN
work_dbbvwgi6and2fokqess5tojy2u	205	44	differently	differently	RB
work_dbbvwgi6and2fokqess5tojy2u	205	45	along	along	IN
work_dbbvwgi6and2fokqess5tojy2u	205	46	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	205	47	medio	medio	NN
work_dbbvwgi6and2fokqess5tojy2u	205	48	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	205	49	lateral	lateral	JJ
work_dbbvwgi6and2fokqess5tojy2u	205	50	gradient	gradient	NN
work_dbbvwgi6and2fokqess5tojy2u	205	51	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	205	52	see	see	VB
work_dbbvwgi6and2fokqess5tojy2u	205	53	comparison	comparison	NN
work_dbbvwgi6and2fokqess5tojy2u	205	54	between	between	IN
work_dbbvwgi6and2fokqess5tojy2u	205	55	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	205	56	8D-8F	8d-8f	CD
work_dbbvwgi6and2fokqess5tojy2u	205	57	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	205	58	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	205	59	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	205	60	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	205	61	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	205	62	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	205	63	8A-8C	8a-8c	CD
work_dbbvwgi6and2fokqess5tojy2u	205	64	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	205	65	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	205	66	Herc2+/+	Herc2+/+	NNP
work_dbbvwgi6and2fokqess5tojy2u	205	67	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	205	68	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	205	69	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	206	1	Thus	thus	RB
work_dbbvwgi6and2fokqess5tojy2u	206	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	206	3	vermal	vermal	JJ
work_dbbvwgi6and2fokqess5tojy2u	206	4	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	206	5	paravermal	paravermal	JJ
work_dbbvwgi6and2fokqess5tojy2u	206	6	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	206	7	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	206	8	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	206	9	less	less	RBR
work_dbbvwgi6and2fokqess5tojy2u	206	10	affected	affected	JJ
work_dbbvwgi6and2fokqess5tojy2u	206	11	than	than	IN
work_dbbvwgi6and2fokqess5tojy2u	206	12	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	206	13	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	206	14	cerebellar	cerebellar	JJ
work_dbbvwgi6and2fokqess5tojy2u	206	15	hemispheres	hemisphere	NNS
work_dbbvwgi6and2fokqess5tojy2u	206	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	207	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	207	2	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	207	3	vermis	vermis	NNP
work_dbbvwgi6and2fokqess5tojy2u	207	4	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	207	5	paravermis	paravermis	NNP
work_dbbvwgi6and2fokqess5tojy2u	207	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	207	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	207	8	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	207	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	207	10	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	207	11	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	207	12	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	207	13	distributed	distribute	VBN
work_dbbvwgi6and2fokqess5tojy2u	207	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	207	15	narrow	narrow	JJ
work_dbbvwgi6and2fokqess5tojy2u	207	16	gaps	gap	NNS
work_dbbvwgi6and2fokqess5tojy2u	207	17	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	207	18	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	207	19	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	207	20	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	207	21	8D	8d	NN
work_dbbvwgi6and2fokqess5tojy2u	207	22	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	207	23	8E	8E	NNP
work_dbbvwgi6and2fokqess5tojy2u	207	24	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	207	25	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	207	26	while	while	IN
work_dbbvwgi6and2fokqess5tojy2u	207	27	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	207	28	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	207	29	hemispheres	hemisphere	NNS
work_dbbvwgi6and2fokqess5tojy2u	207	30	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	207	31	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	207	32	areas	area	NNS
work_dbbvwgi6and2fokqess5tojy2u	207	33	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	207	34	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	207	35	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	207	36	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	207	37	reached	reach	VBD
work_dbbvwgi6and2fokqess5tojy2u	207	38	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	207	39	great	great	JJ
work_dbbvwgi6and2fokqess5tojy2u	207	40	extension	extension	NN
work_dbbvwgi6and2fokqess5tojy2u	207	41	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	207	42	arrowheads	arrowhead	NNS
work_dbbvwgi6and2fokqess5tojy2u	207	43	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	207	44	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	207	45	8D	8d	NN
work_dbbvwgi6and2fokqess5tojy2u	207	46	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	207	47	8F	8f	NN
work_dbbvwgi6and2fokqess5tojy2u	207	48	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	207	49	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	207	50	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	207	51	which	which	WDT
work_dbbvwgi6and2fokqess5tojy2u	207	52	remain	remain	VBP
work_dbbvwgi6and2fokqess5tojy2u	207	53	some	some	DT
work_dbbvwgi6and2fokqess5tojy2u	207	54	surviving	survive	VBG
work_dbbvwgi6and2fokqess5tojy2u	207	55	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	207	56	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	207	57	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	207	58	small	small	JJ
work_dbbvwgi6and2fokqess5tojy2u	207	59	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	207	60	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	207	61	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	207	62	8F	8f	NN
work_dbbvwgi6and2fokqess5tojy2u	207	63	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	207	64	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	208	1	Epifluorescence	epifluorescence	NN
work_dbbvwgi6and2fokqess5tojy2u	208	2	microscopy	microscopy	JJ
work_dbbvwgi6and2fokqess5tojy2u	208	3	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	208	4	showed	show	VBD
work_dbbvwgi6and2fokqess5tojy2u	208	5	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	208	6	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	208	7	immunoreactivy	immunoreactivy	NN
work_dbbvwgi6and2fokqess5tojy2u	208	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	208	9	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	208	10	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	208	11	colocalize	colocalize	VBP
work_dbbvwgi6and2fokqess5tojy2u	208	12	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	208	13	CaBP	CaBP	NNP
work_dbbvwgi6and2fokqess5tojy2u	208	14	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	208	15	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	208	16	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	208	17	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	208	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	209	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	209	2	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	209	3	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	209	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	209	5	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	209	6	immunohistochemistry	immunohistochemistry	NNP
work_dbbvwgi6and2fokqess5tojy2u	209	7	confirmed	confirm	VBD
work_dbbvwgi6and2fokqess5tojy2u	209	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	209	9	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	209	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	209	11	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	209	12	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	209	13	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	209	14	narrow	narrow	JJ
work_dbbvwgi6and2fokqess5tojy2u	209	15	gaps	gap	NNS
work_dbbvwgi6and2fokqess5tojy2u	209	16	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	209	17	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	209	18	vermis	vermis	NNP
work_dbbvwgi6and2fokqess5tojy2u	209	19	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	209	20	paravermis	paravermis	NNP
work_dbbvwgi6and2fokqess5tojy2u	209	21	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	209	22	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	209	23	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	209	24	greater	great	JJR
work_dbbvwgi6and2fokqess5tojy2u	209	25	extension	extension	NN
work_dbbvwgi6and2fokqess5tojy2u	209	26	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	209	27	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	209	28	hemispheres	hemisphere	NNS
work_dbbvwgi6and2fokqess5tojy2u	209	29	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	209	30	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	209	31	9C-9E	9c-9e	CD
work_dbbvwgi6and2fokqess5tojy2u	209	32	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	209	33	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	210	1	CaBP	CaBP	NNP
work_dbbvwgi6and2fokqess5tojy2u	210	2	immunohistochemistry	immunohistochemistry	NNP
work_dbbvwgi6and2fokqess5tojy2u	210	3	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	210	4	revealed	reveal	VBD
work_dbbvwgi6and2fokqess5tojy2u	210	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	210	6	presence	presence	NN
work_dbbvwgi6and2fokqess5tojy2u	210	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	210	8	pathological	pathological	JJ
work_dbbvwgi6and2fokqess5tojy2u	210	9	signs	sign	NNS
work_dbbvwgi6and2fokqess5tojy2u	210	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	210	11	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	210	12	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	210	13	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	210	14	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	211	1	Rounded	rounded	JJ
work_dbbvwgi6and2fokqess5tojy2u	211	2	thickenings	thickening	NNS
work_dbbvwgi6and2fokqess5tojy2u	211	3	resembling	resemble	VBG
work_dbbvwgi6and2fokqess5tojy2u	211	4	axonal	axonal	JJ
work_dbbvwgi6and2fokqess5tojy2u	211	5	torpedoes	torpedo	NNS
work_dbbvwgi6and2fokqess5tojy2u	211	6	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	211	7	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	211	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	211	9	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	211	10	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	211	11	axons	axon	NNS
work_dbbvwgi6and2fokqess5tojy2u	211	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	211	13	which	which	WDT
work_dbbvwgi6and2fokqess5tojy2u	211	14	contrast	contrast	NN
work_dbbvwgi6and2fokqess5tojy2u	211	15	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	211	16	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	211	17	fine	fine	JJ
work_dbbvwgi6and2fokqess5tojy2u	211	18	grained	grain	VBN
work_dbbvwgi6and2fokqess5tojy2u	211	19	morphology	morphology	NN
work_dbbvwgi6and2fokqess5tojy2u	211	20	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	211	21	normal	normal	JJ
work_dbbvwgi6and2fokqess5tojy2u	211	22	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	211	23	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	211	24	axonal	axonal	JJ
work_dbbvwgi6and2fokqess5tojy2u	211	25	plexuses	plexus	NNS
work_dbbvwgi6and2fokqess5tojy2u	211	26	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	211	27	see	see	VB
work_dbbvwgi6and2fokqess5tojy2u	211	28	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	211	29	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	211	30	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	211	31	comparison	comparison	NN
work_dbbvwgi6and2fokqess5tojy2u	211	32	between	between	IN
work_dbbvwgi6and2fokqess5tojy2u	211	33	Herc2+/+	Herc2+/+	NNP
work_dbbvwgi6and2fokqess5tojy2u	211	34	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	211	35	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	211	36	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	211	37	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	211	38	10A-10C	10a-10c	CD
work_dbbvwgi6and2fokqess5tojy2u	211	39	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	211	40	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	212	1	Phenotypic	phenotypic	JJ
work_dbbvwgi6and2fokqess5tojy2u	212	2	alterations	alteration	NNS
work_dbbvwgi6and2fokqess5tojy2u	212	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	212	4	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	212	5	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	212	6	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	212	7	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	212	8	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	212	9	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	212	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	212	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	212	12	1.5	1.5	CD
work_dbbvwgi6and2fokqess5tojy2u	212	13	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	212	14	thick	thick	JJ
work_dbbvwgi6and2fokqess5tojy2u	212	15	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	212	16	stained	stain	VBN
work_dbbvwgi6and2fokqess5tojy2u	212	17	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	212	18	toluidine	toluidine	JJ
work_dbbvwgi6and2fokqess5tojy2u	212	19	blue	blue	NN
work_dbbvwgi6and2fokqess5tojy2u	212	20	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	212	21	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	212	22	10D-10E	10D-10E	NNS
work_dbbvwgi6and2fokqess5tojy2u	212	23	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	212	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	213	1	Disappeared	disappear	VBD
work_dbbvwgi6and2fokqess5tojy2u	213	2	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	213	3	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	213	4	somata	somata	NN
work_dbbvwgi6and2fokqess5tojy2u	213	5	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	213	6	substituted	substitute	VBN
work_dbbvwgi6and2fokqess5tojy2u	213	7	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	213	8	glial	glial	JJ
work_dbbvwgi6and2fokqess5tojy2u	213	9	Golgi	Golgi	NNP
work_dbbvwgi6and2fokqess5tojy2u	213	10	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	213	11	epithelial	epithelial	JJ
work_dbbvwgi6and2fokqess5tojy2u	213	12	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	213	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	213	14	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	213	15	10D	10D	NNP
work_dbbvwgi6and2fokqess5tojy2u	213	16	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	213	17	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	213	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	213	19	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	213	20	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	213	21	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	213	22	small	small	JJ
work_dbbvwgi6and2fokqess5tojy2u	213	23	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	213	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	213	25	Golgi	Golgi	NNP
work_dbbvwgi6and2fokqess5tojy2u	213	26	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	213	27	epithelial	epithelial	JJ
work_dbbvwgi6and2fokqess5tojy2u	213	28	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	213	29	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	213	30	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	214	1	High	high	JJ
work_dbbvwgi6and2fokqess5tojy2u	214	2	magnification	magnification	NN
work_dbbvwgi6and2fokqess5tojy2u	214	3	allowed	allow	VBN
work_dbbvwgi6and2fokqess5tojy2u	214	4	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	214	5	detect	detect	VB
work_dbbvwgi6and2fokqess5tojy2u	214	6	degenerative	degenerative	JJ
work_dbbvwgi6and2fokqess5tojy2u	214	7	dark	dark	JJ
work_dbbvwgi6and2fokqess5tojy2u	214	8	accumulations	accumulation	NNS
work_dbbvwgi6and2fokqess5tojy2u	214	9	within	within	IN
work_dbbvwgi6and2fokqess5tojy2u	214	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	214	11	cytoplasm	cytoplasm	NN
work_dbbvwgi6and2fokqess5tojy2u	214	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	214	13	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	214	14	soma	soma	NN
work_dbbvwgi6and2fokqess5tojy2u	214	15	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	214	16	arrowheads	arrowhead	NNS
work_dbbvwgi6and2fokqess5tojy2u	214	17	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	214	18	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	214	19	10E	10E	NNP
work_dbbvwgi6and2fokqess5tojy2u	214	20	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	214	21	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	214	22	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	214	23	dendrites	dendrite	NNS
work_dbbvwgi6and2fokqess5tojy2u	214	24	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	214	25	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	214	26	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	214	27	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	214	28	10E	10E	NNP
work_dbbvwgi6and2fokqess5tojy2u	214	29	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	214	30	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	214	31	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	214	32	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	214	33	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	214	34	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	215	1	Electron	Electron	NNP
work_dbbvwgi6and2fokqess5tojy2u	215	2	microscopy	microscopy	JJ
work_dbbvwgi6and2fokqess5tojy2u	215	3	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	215	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	215	5	cerebella	cerebella	NN
work_dbbvwgi6and2fokqess5tojy2u	215	6	confirmed	confirm	VBD
work_dbbvwgi6and2fokqess5tojy2u	215	7	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	215	8	degenerative	degenerative	JJ
work_dbbvwgi6and2fokqess5tojy2u	215	9	signs	sign	NNS
work_dbbvwgi6and2fokqess5tojy2u	215	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	215	11	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	215	12	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	215	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	215	14	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	215	15	10F-10H	10F-10H	NNS
work_dbbvwgi6and2fokqess5tojy2u	215	16	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	215	17	11	11	CD
work_dbbvwgi6and2fokqess5tojy2u	215	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	215	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	216	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	216	2	cytoplasm	cytoplasm	NN
work_dbbvwgi6and2fokqess5tojy2u	216	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	216	4	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	216	5	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	216	6	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	216	7	contained	contain	VBD
work_dbbvwgi6and2fokqess5tojy2u	216	8	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	216	9	high	high	JJ
work_dbbvwgi6and2fokqess5tojy2u	216	10	number	number	NN
work_dbbvwgi6and2fokqess5tojy2u	216	11	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	216	12	lysosomes	lysosome	NNS
work_dbbvwgi6and2fokqess5tojy2u	216	13	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	216	14	electron	electron	NN
work_dbbvwgi6and2fokqess5tojy2u	216	15	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	216	16	dense	dense	JJ
work_dbbvwgi6and2fokqess5tojy2u	216	17	debris	debris	NN
work_dbbvwgi6and2fokqess5tojy2u	216	18	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	216	19	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	216	20	10F-10H	10F-10H	NNS
work_dbbvwgi6and2fokqess5tojy2u	216	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	216	22	asterisks	asterisks	RB
work_dbbvwgi6and2fokqess5tojy2u	216	23	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	216	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	216	25	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	216	26	autophagosomes	autophagosome	VBZ
work_dbbvwgi6and2fokqess5tojy2u	216	27	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	216	28	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	216	29	degrees	degree	NNS
work_dbbvwgi6and2fokqess5tojy2u	216	30	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	216	31	evolution	evolution	NN
work_dbbvwgi6and2fokqess5tojy2u	216	32	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	216	33	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	216	34	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	216	35	G	g	NN
work_dbbvwgi6and2fokqess5tojy2u	216	36	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	216	37	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	216	38	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	216	39	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	217	1	Damaged	damaged	JJ
work_dbbvwgi6and2fokqess5tojy2u	217	2	cisterns	cistern	NNS
work_dbbvwgi6and2fokqess5tojy2u	217	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	217	4	Golgi	Golgi	NNP
work_dbbvwgi6and2fokqess5tojy2u	217	5	apparatus	apparatus	NN
work_dbbvwgi6and2fokqess5tojy2u	217	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	217	7	numerous	numerous	JJ
work_dbbvwgi6and2fokqess5tojy2u	217	8	cisterns	cistern	NNS
work_dbbvwgi6and2fokqess5tojy2u	217	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	217	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	217	11	rough	rough	JJ
work_dbbvwgi6and2fokqess5tojy2u	217	12	endoplasmic	endoplasmic	JJ
work_dbbvwgi6and2fokqess5tojy2u	217	13	reticulum	reticulum	NN
work_dbbvwgi6and2fokqess5tojy2u	217	14	fused	fuse	VBN
work_dbbvwgi6and2fokqess5tojy2u	217	15	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	217	16	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	217	17	cytoplasmic	cytoplasmic	JJ
work_dbbvwgi6and2fokqess5tojy2u	217	18	face	face	NN
work_dbbvwgi6and2fokqess5tojy2u	217	19	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	217	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	217	21	nuclear	nuclear	JJ
work_dbbvwgi6and2fokqess5tojy2u	217	22	membrane	membrane	NN
work_dbbvwgi6and2fokqess5tojy2u	217	23	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	217	24	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	217	25	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	217	26	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	217	27	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	217	28	shown	show	VBN
work_dbbvwgi6and2fokqess5tojy2u	217	29	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	217	30	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	218	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	218	2	difference	difference	NN
work_dbbvwgi6and2fokqess5tojy2u	218	3	between	between	IN
work_dbbvwgi6and2fokqess5tojy2u	218	4	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	218	5	Herc2+/+	Herc2+/+	NNP
work_dbbvwgi6and2fokqess5tojy2u	218	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	218	7	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	218	8	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	218	9	even	even	RB
work_dbbvwgi6and2fokqess5tojy2u	218	10	most	most	RBS
work_dbbvwgi6and2fokqess5tojy2u	218	11	evident	evident	JJ
work_dbbvwgi6and2fokqess5tojy2u	218	12	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	218	13	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	218	14	principal	principal	JJ
work_dbbvwgi6and2fokqess5tojy2u	218	15	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	218	16	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	218	17	dendrites	dendrite	NNS
work_dbbvwgi6and2fokqess5tojy2u	218	18	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	218	19	Pcd	Pcd	NNP
work_dbbvwgi6and2fokqess5tojy2u	218	20	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	218	21	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	218	22	11	11	CD
work_dbbvwgi6and2fokqess5tojy2u	218	23	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	218	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	219	1	Thus	thus	RB
work_dbbvwgi6and2fokqess5tojy2u	219	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	219	3	numerous	numerous	JJ
work_dbbvwgi6and2fokqess5tojy2u	219	4	degenerative	degenerative	JJ
work_dbbvwgi6and2fokqess5tojy2u	219	5	signs	sign	NNS
work_dbbvwgi6and2fokqess5tojy2u	219	6	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	219	7	present	present	JJ
work_dbbvwgi6and2fokqess5tojy2u	219	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	219	9	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	219	10	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	219	11	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	219	12	dendrite	dendrite	VBP
work_dbbvwgi6and2fokqess5tojy2u	219	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	219	14	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	219	15	11B	11B	NNS
work_dbbvwgi6and2fokqess5tojy2u	219	16	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	219	17	11E	11e	CD
work_dbbvwgi6and2fokqess5tojy2u	219	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	219	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	219	20	while	while	IN
work_dbbvwgi6and2fokqess5tojy2u	219	21	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	219	22	almost	almost	RB
work_dbbvwgi6and2fokqess5tojy2u	219	23	absent	absent	JJ
work_dbbvwgi6and2fokqess5tojy2u	219	24	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	219	25	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	219	26	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	219	27	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	219	28	ones	one	NNS
work_dbbvwgi6and2fokqess5tojy2u	219	29	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	219	30	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	219	31	11A	11A	NNP
work_dbbvwgi6and2fokqess5tojy2u	219	32	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	219	33	11C	11C	NNP
work_dbbvwgi6and2fokqess5tojy2u	219	34	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	219	35	11D	11D	NNP
work_dbbvwgi6and2fokqess5tojy2u	219	36	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	219	37	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	220	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	220	2	degenerative	degenerative	JJ
work_dbbvwgi6and2fokqess5tojy2u	220	3	signs	sign	NNS
work_dbbvwgi6and2fokqess5tojy2u	220	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	220	5	found	find	VBN
work_dbbvwgi6and2fokqess5tojy2u	220	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	220	7	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	220	8	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	220	9	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	220	10	month	month	NN
work_dbbvwgi6and2fokqess5tojy2u	220	11	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	220	12	old	old	JJ
work_dbbvwgi6and2fokqess5tojy2u	220	13	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	220	14	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	220	15	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	220	16	10F-10H	10f-10h	CD
work_dbbvwgi6and2fokqess5tojy2u	220	17	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	220	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	220	19	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	220	20	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	220	21	slight	slight	JJ
work_dbbvwgi6and2fokqess5tojy2u	220	22	increase	increase	NN
work_dbbvwgi6and2fokqess5tojy2u	220	23	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	220	24	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	220	25	alterations	alteration	NNS
work_dbbvwgi6and2fokqess5tojy2u	220	26	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	220	27	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	220	28	older	old	JJR
work_dbbvwgi6and2fokqess5tojy2u	220	29	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	220	30	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	220	31	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	220	32	shown	show	VBN
work_dbbvwgi6and2fokqess5tojy2u	220	33	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	220	34	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	221	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	221	2	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	221	3	show	show	VBP
work_dbbvwgi6and2fokqess5tojy2u	221	4	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	221	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	221	6	partial	partial	JJ
work_dbbvwgi6and2fokqess5tojy2u	221	7	inactivation	inactivation	NN
work_dbbvwgi6and2fokqess5tojy2u	221	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	221	9	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	221	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	221	11	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	221	12	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	221	13	causes	cause	VBZ
work_dbbvwgi6and2fokqess5tojy2u	221	14	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	221	15	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	221	16	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	221	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	221	18	which	which	WDT
work_dbbvwgi6and2fokqess5tojy2u	221	19	explain	explain	VBP
work_dbbvwgi6and2fokqess5tojy2u	221	20	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	221	21	incoordination	incoordination	NNP
work_dbbvwgi6and2fokqess5tojy2u	221	22	detected	detect	VBN
work_dbbvwgi6and2fokqess5tojy2u	221	23	here	here	RB
work_dbbvwgi6and2fokqess5tojy2u	221	24	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	221	25	rotarod	rotarod	NNP
work_dbbvwgi6and2fokqess5tojy2u	221	26	test	test	NN
work_dbbvwgi6and2fokqess5tojy2u	221	27	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	222	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	222	2	increase	increase	NN
work_dbbvwgi6and2fokqess5tojy2u	222	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	222	4	autophagosomes	autophagosome	NNS
work_dbbvwgi6and2fokqess5tojy2u	222	5	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	222	6	lysosomes	lysosome	NNS
work_dbbvwgi6and2fokqess5tojy2u	222	7	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	222	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	222	9	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	222	10	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	222	11	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	222	12	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	222	13	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	222	14	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	222	15	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	222	16	11	11	CD
work_dbbvwgi6and2fokqess5tojy2u	222	17	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	222	18	led	lead	VBD
work_dbbvwgi6and2fokqess5tojy2u	222	19	us	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	222	20	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	222	21	wonder	wonder	VB
work_dbbvwgi6and2fokqess5tojy2u	222	22	whether	whether	IN
work_dbbvwgi6and2fokqess5tojy2u	222	23	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	222	24	may	may	MD
work_dbbvwgi6and2fokqess5tojy2u	222	25	be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	222	26	involved	involve	VBN
work_dbbvwgi6and2fokqess5tojy2u	222	27	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	222	28	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	222	29	regulation	regulation	NN
work_dbbvwgi6and2fokqess5tojy2u	222	30	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	222	31	autophagy	autophagy	NN
work_dbbvwgi6and2fokqess5tojy2u	222	32	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	223	1	To	to	IN
work_dbbvwgi6and2fokqess5tojy2u	223	2	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	223	3	end	end	NN
work_dbbvwgi6and2fokqess5tojy2u	223	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	223	5	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	223	6	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	223	7	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	223	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	223	9	adaptor	adaptor	NN
work_dbbvwgi6and2fokqess5tojy2u	223	10	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	223	11	substrate	substrate	NN
work_dbbvwgi6and2fokqess5tojy2u	223	12	p62	p62	NN
work_dbbvwgi6and2fokqess5tojy2u	223	13	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	223	14	SQSTM1	SQSTM1	NNS
work_dbbvwgi6and2fokqess5tojy2u	223	15	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	223	16	laser	laser	NN
work_dbbvwgi6and2fokqess5tojy2u	223	17	confocal	confocal	NN
work_dbbvwgi6and2fokqess5tojy2u	223	18	microscopy	microscopy	NN
work_dbbvwgi6and2fokqess5tojy2u	223	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	224	1	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	224	2	immunostaining	immunostaine	VBG
work_dbbvwgi6and2fokqess5tojy2u	224	3	colocalized	colocalize	VBN
work_dbbvwgi6and2fokqess5tojy2u	224	4	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	224	5	p62	p62	NN
work_dbbvwgi6and2fokqess5tojy2u	224	6	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	224	7	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	224	8	12	12	CD
work_dbbvwgi6and2fokqess5tojy2u	224	9	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	224	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	225	1	This	this	DT
work_dbbvwgi6and2fokqess5tojy2u	225	2	colocalization	colocalization	NN
work_dbbvwgi6and2fokqess5tojy2u	225	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	225	4	it	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	225	5	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	225	6	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	225	7	both	both	DT
work_dbbvwgi6and2fokqess5tojy2u	225	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	225	9	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	225	10	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	225	11	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	225	12	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	225	13	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	225	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	225	15	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	225	16	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	225	17	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	225	18	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	225	19	12	12	CD
work_dbbvwgi6and2fokqess5tojy2u	225	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	225	21	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	225	22	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	225	23	arrowheads	arrowhead	NNS
work_dbbvwgi6and2fokqess5tojy2u	225	24	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	225	25	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	225	26	merged	merge	VBN
work_dbbvwgi6and2fokqess5tojy2u	225	27	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	225	28	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	226	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	226	2	Herc+/+	herc+/+	CD
work_dbbvwgi6and2fokqess5tojy2u	226	3	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	226	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	226	5	p62	p62	NN
work_dbbvwgi6and2fokqess5tojy2u	226	6	immunostaining	immunostaine	VBG
work_dbbvwgi6and2fokqess5tojy2u	226	7	showed	show	VBD
work_dbbvwgi6and2fokqess5tojy2u	226	8	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	226	9	punctate	punctate	NN
work_dbbvwgi6and2fokqess5tojy2u	226	10	labeling	labeling	NN
work_dbbvwgi6and2fokqess5tojy2u	226	11	pattern	pattern	NN
work_dbbvwgi6and2fokqess5tojy2u	226	12	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	226	13	concentrated	concentrate	VBD
work_dbbvwgi6and2fokqess5tojy2u	226	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	226	15	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	226	16	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	226	17	somata	somata	NN
work_dbbvwgi6and2fokqess5tojy2u	226	18	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	226	19	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	226	20	12	12	CD
work_dbbvwgi6and2fokqess5tojy2u	226	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	226	22	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	226	23	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	226	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	227	1	This	this	DT
work_dbbvwgi6and2fokqess5tojy2u	227	2	pattern	pattern	NN
work_dbbvwgi6and2fokqess5tojy2u	227	3	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	227	4	altered	alter	VBN
work_dbbvwgi6and2fokqess5tojy2u	227	5	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	227	6	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	227	7	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	227	8	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	227	9	thus	thus	RB
work_dbbvwgi6and2fokqess5tojy2u	227	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	227	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	227	12	addition	addition	NN
work_dbbvwgi6and2fokqess5tojy2u	227	13	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	227	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	227	15	somatic	somatic	JJ
work_dbbvwgi6and2fokqess5tojy2u	227	16	labeling	labeling	NN
work_dbbvwgi6and2fokqess5tojy2u	227	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	227	18	p62	p62	NN
work_dbbvwgi6and2fokqess5tojy2u	227	19	immunostaining	immunostaining	NN
work_dbbvwgi6and2fokqess5tojy2u	227	20	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	227	21	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	227	22	evident	evident	JJ
work_dbbvwgi6and2fokqess5tojy2u	227	23	within	within	IN
work_dbbvwgi6and2fokqess5tojy2u	227	24	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	227	25	dendritic	dendritic	JJ
work_dbbvwgi6and2fokqess5tojy2u	227	26	trees	tree	NNS
work_dbbvwgi6and2fokqess5tojy2u	227	27	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	227	28	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	227	29	axonal	axonal	JJ
work_dbbvwgi6and2fokqess5tojy2u	227	30	torpedoes	torpedo	NNS
work_dbbvwgi6and2fokqess5tojy2u	227	31	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	227	32	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	227	33	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	227	34	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	227	35	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	227	36	12	12	CD
work_dbbvwgi6and2fokqess5tojy2u	227	37	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	227	38	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	227	39	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	227	40	arrowheads	arrowhead	NNS
work_dbbvwgi6and2fokqess5tojy2u	227	41	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	227	42	indicating	indicate	VBG
work_dbbvwgi6and2fokqess5tojy2u	227	43	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	227	44	dysregulation	dysregulation	NN
work_dbbvwgi6and2fokqess5tojy2u	227	45	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	227	46	autophagy	autophagy	NN
work_dbbvwgi6and2fokqess5tojy2u	227	47	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	227	48	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	227	49	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	227	50	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	227	51	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	228	1	Altogether	altogether	RB
work_dbbvwgi6and2fokqess5tojy2u	228	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	228	3	Oncotarget56094www.impactjournals.com/oncotarget	Oncotarget56094www.impactjournals.com/oncotarget	``
work_dbbvwgi6and2fokqess5tojy2u	228	4	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	228	5	8	8	CD
work_dbbvwgi6and2fokqess5tojy2u	228	6	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	228	7	Purkinje	purkinje	NN
work_dbbvwgi6and2fokqess5tojy2u	228	8	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	228	9	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	228	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	228	11	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	228	12	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	228	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	229	1	Microphotographs	microphotograph	NNS
work_dbbvwgi6and2fokqess5tojy2u	229	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	229	3	coronal	coronal	JJ
work_dbbvwgi6and2fokqess5tojy2u	229	4	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	229	5	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	229	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	229	7	cerebellar	cerebellar	JJ
work_dbbvwgi6and2fokqess5tojy2u	229	8	cortex	cortex	NN
work_dbbvwgi6and2fokqess5tojy2u	229	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	229	10	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	229	11	months	month	NNS
work_dbbvwgi6and2fokqess5tojy2u	229	12	old	old	JJ
work_dbbvwgi6and2fokqess5tojy2u	229	13	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	229	14	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	229	15	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	229	16	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	229	17	wt	wt	VB
work_dbbvwgi6and2fokqess5tojy2u	229	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	229	19	A	a	NN
work_dbbvwgi6and2fokqess5tojy2u	229	20	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	229	21	c	c	NNP
work_dbbvwgi6and2fokqess5tojy2u	229	22	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	229	23	G	g	NN
work_dbbvwgi6and2fokqess5tojy2u	229	24	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	229	25	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	229	26	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	229	27	months	month	NNS
work_dbbvwgi6and2fokqess5tojy2u	229	28	old	old	JJ
work_dbbvwgi6and2fokqess5tojy2u	229	29	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	229	30	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	229	31	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	229	32	+	+	NNP
work_dbbvwgi6and2fokqess5tojy2u	229	33	/530	/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	229	34	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	229	35	D	D	NNP
work_dbbvwgi6and2fokqess5tojy2u	229	36	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	229	37	F	F	NNP
work_dbbvwgi6and2fokqess5tojy2u	229	38	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	229	39	H	H	NNP
work_dbbvwgi6and2fokqess5tojy2u	229	40	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	229	41	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	230	1	Calbindin	Calbindin	NNP
work_dbbvwgi6and2fokqess5tojy2u	230	2	immunohistochemistry	immunohistochemistry	NN
work_dbbvwgi6and2fokqess5tojy2u	230	3	shows	show	NNS
work_dbbvwgi6and2fokqess5tojy2u	230	4	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	230	5	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	230	6	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	230	7	somata	somata	NN
work_dbbvwgi6and2fokqess5tojy2u	230	8	form	form	VBP
work_dbbvwgi6and2fokqess5tojy2u	230	9	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	230	10	continuous	continuous	JJ
work_dbbvwgi6and2fokqess5tojy2u	230	11	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	230	12	layer	layer	NN
work_dbbvwgi6and2fokqess5tojy2u	230	13	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	230	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	230	15	Herc2+/+	herc2+/+	NN
work_dbbvwgi6and2fokqess5tojy2u	230	16	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	230	17	wt	wt	NN
work_dbbvwgi6and2fokqess5tojy2u	230	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	230	19	cerebellum	cerebellum	NN
work_dbbvwgi6and2fokqess5tojy2u	230	20	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	230	21	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	230	22	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	230	23	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	230	24	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	230	25	However	however	RB
work_dbbvwgi6and2fokqess5tojy2u	230	26	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	230	27	parasagittal	parasagittal	JJ
work_dbbvwgi6and2fokqess5tojy2u	230	28	zones	zone	NNS
work_dbbvwgi6and2fokqess5tojy2u	230	29	lacking	lacking	NN
work_dbbvwgi6and2fokqess5tojy2u	230	30	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	230	31	immunoreactivity	immunoreactivity	NN
work_dbbvwgi6and2fokqess5tojy2u	230	32	throughout	throughout	IN
work_dbbvwgi6and2fokqess5tojy2u	230	33	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	230	34	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	230	35	cerebellum	cerebellum	NN
work_dbbvwgi6and2fokqess5tojy2u	230	36	indicative	indicative	JJ
work_dbbvwgi6and2fokqess5tojy2u	230	37	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	230	38	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	230	39	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	230	40	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	230	41	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	230	42	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	230	43	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	230	44	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	230	45	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	230	46	arrowheads	arrowhead	NNS
work_dbbvwgi6and2fokqess5tojy2u	230	47	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	230	48	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	230	49	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	230	50	D	D	NNP
work_dbbvwgi6and2fokqess5tojy2u	230	51	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	230	52	F	f	NN
work_dbbvwgi6and2fokqess5tojy2u	230	53	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	230	54	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	231	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	231	2	symmetrical	symmetrical	JJ
work_dbbvwgi6and2fokqess5tojy2u	231	3	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	231	4	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	231	5	deprived	deprive	VBD
work_dbbvwgi6and2fokqess5tojy2u	231	6	bands	band	NNS
work_dbbvwgi6and2fokqess5tojy2u	231	7	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	231	8	characterized	characterize	VBN
work_dbbvwgi6and2fokqess5tojy2u	231	9	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	231	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	231	11	presence	presence	NN
work_dbbvwgi6and2fokqess5tojy2u	231	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	231	13	wide	wide	JJ
work_dbbvwgi6and2fokqess5tojy2u	231	14	spaces	space	NNS
work_dbbvwgi6and2fokqess5tojy2u	231	15	lacking	lack	VBG
work_dbbvwgi6and2fokqess5tojy2u	231	16	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	231	17	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	231	18	somata	somata	NN
work_dbbvwgi6and2fokqess5tojy2u	231	19	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	231	20	H	h	NN
work_dbbvwgi6and2fokqess5tojy2u	231	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	231	22	asterisks	asterisk	VBZ
work_dbbvwgi6and2fokqess5tojy2u	231	23	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	231	24	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	231	25	dendritic	dendritic	JJ
work_dbbvwgi6and2fokqess5tojy2u	231	26	debris	debris	NN
work_dbbvwgi6and2fokqess5tojy2u	231	27	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	231	28	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	231	29	molecular	molecular	JJ
work_dbbvwgi6and2fokqess5tojy2u	231	30	layer	layer	NN
work_dbbvwgi6and2fokqess5tojy2u	231	31	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	231	32	H	h	NN
work_dbbvwgi6and2fokqess5tojy2u	231	33	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	231	34	mol	mol	NN
work_dbbvwgi6and2fokqess5tojy2u	231	35	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	231	36	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	231	37	distribute	distribute	VB
work_dbbvwgi6and2fokqess5tojy2u	231	38	differently	differently	RB
work_dbbvwgi6and2fokqess5tojy2u	231	39	according	accord	VBG
work_dbbvwgi6and2fokqess5tojy2u	231	40	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	231	41	medio	medio	NN
work_dbbvwgi6and2fokqess5tojy2u	231	42	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	231	43	lateral	lateral	JJ
work_dbbvwgi6and2fokqess5tojy2u	231	44	gradient	gradient	NN
work_dbbvwgi6and2fokqess5tojy2u	231	45	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	232	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	232	2	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	232	3	vermis	vermi	NNS
work_dbbvwgi6and2fokqess5tojy2u	232	4	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	232	5	paravermal	paravermal	NNP
work_dbbvwgi6and2fokqess5tojy2u	232	6	zones	zone	VBZ
work_dbbvwgi6and2fokqess5tojy2u	232	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	232	8	immunonegative	immunonegative	JJ
work_dbbvwgi6and2fokqess5tojy2u	232	9	zones	zone	NNS
work_dbbvwgi6and2fokqess5tojy2u	232	10	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	232	11	sagittaly	sagittaly	RB
work_dbbvwgi6and2fokqess5tojy2u	232	12	distributed	distributed	JJ
work_dbbvwgi6and2fokqess5tojy2u	232	13	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	232	14	narrow	narrow	JJ
work_dbbvwgi6and2fokqess5tojy2u	232	15	gaps	gap	NNS
work_dbbvwgi6and2fokqess5tojy2u	232	16	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	232	17	D	d	NN
work_dbbvwgi6and2fokqess5tojy2u	232	18	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	232	19	E	e	NN
work_dbbvwgi6and2fokqess5tojy2u	232	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	232	21	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	232	22	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	232	23	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	232	24	while	while	IN
work_dbbvwgi6and2fokqess5tojy2u	232	25	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	232	26	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	232	27	hemispheres	hemisphere	NNS
work_dbbvwgi6and2fokqess5tojy2u	232	28	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	232	29	areas	area	NNS
work_dbbvwgi6and2fokqess5tojy2u	232	30	devoid	devoid	JJ
work_dbbvwgi6and2fokqess5tojy2u	232	31	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	232	32	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	232	33	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	232	34	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	232	35	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	232	36	bilateral	bilateral	JJ
work_dbbvwgi6and2fokqess5tojy2u	232	37	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	232	38	reach	reach	VB
work_dbbvwgi6and2fokqess5tojy2u	232	39	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	232	40	greater	great	JJR
work_dbbvwgi6and2fokqess5tojy2u	232	41	extension	extension	NN
work_dbbvwgi6and2fokqess5tojy2u	232	42	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	232	43	D	d	NN
work_dbbvwgi6and2fokqess5tojy2u	232	44	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	232	45	F	f	NN
work_dbbvwgi6and2fokqess5tojy2u	232	46	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	232	47	arrowheads	arrowhead	NNS
work_dbbvwgi6and2fokqess5tojy2u	232	48	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	232	49	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	232	50	which	which	WDT
work_dbbvwgi6and2fokqess5tojy2u	232	51	remain	remain	VBP
work_dbbvwgi6and2fokqess5tojy2u	232	52	some	some	DT
work_dbbvwgi6and2fokqess5tojy2u	232	53	surviving	survive	VBG
work_dbbvwgi6and2fokqess5tojy2u	232	54	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	232	55	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	232	56	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	232	57	F	f	NN
work_dbbvwgi6and2fokqess5tojy2u	232	58	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	232	59	small	small	JJ
work_dbbvwgi6and2fokqess5tojy2u	232	60	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	232	61	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	232	62	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	233	1	G	G	NNP
work_dbbvwgi6and2fokqess5tojy2u	233	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	233	3	illustrates	illustrate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	233	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	233	5	Herc2+/+	herc2+/+	NN
work_dbbvwgi6and2fokqess5tojy2u	233	6	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	233	7	wt	wt	NNP
work_dbbvwgi6and2fokqess5tojy2u	233	8	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	233	9	immunostaining	immunostaining	JJ
work_dbbvwgi6and2fokqess5tojy2u	233	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	233	11	normal	normal	JJ
work_dbbvwgi6and2fokqess5tojy2u	233	12	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	233	13	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	233	14	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	233	15	note	note	VB
work_dbbvwgi6and2fokqess5tojy2u	233	16	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	233	17	dendritic	dendritic	JJ
work_dbbvwgi6and2fokqess5tojy2u	233	18	trees	tree	NNS
work_dbbvwgi6and2fokqess5tojy2u	233	19	fulfill	fulfill	VBP
work_dbbvwgi6and2fokqess5tojy2u	233	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	233	21	molecular	molecular	JJ
work_dbbvwgi6and2fokqess5tojy2u	233	22	layer	layer	NN
work_dbbvwgi6and2fokqess5tojy2u	233	23	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	233	24	G	g	NN
work_dbbvwgi6and2fokqess5tojy2u	233	25	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	233	26	mol	mol	NN
work_dbbvwgi6and2fokqess5tojy2u	233	27	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	233	28	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	233	29	while	while	IN
work_dbbvwgi6and2fokqess5tojy2u	233	30	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	233	31	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	233	32	somata	somata	VBP
work_dbbvwgi6and2fokqess5tojy2u	233	33	align	align	VBP
work_dbbvwgi6and2fokqess5tojy2u	233	34	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	233	35	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	233	36	continuous	continuous	JJ
work_dbbvwgi6and2fokqess5tojy2u	233	37	row	row	NN
work_dbbvwgi6and2fokqess5tojy2u	233	38	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	234	1	PCl	PCl	NNS
work_dbbvwgi6and2fokqess5tojy2u	234	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	234	3	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	234	4	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	234	5	layer	layer	VBP
work_dbbvwgi6and2fokqess5tojy2u	234	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	235	1	Bars	bar	NNS
work_dbbvwgi6and2fokqess5tojy2u	235	2	=	=	NFP
work_dbbvwgi6and2fokqess5tojy2u	235	3	600	600	CD
work_dbbvwgi6and2fokqess5tojy2u	235	4	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	235	5	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	235	6	A	a	NN
work_dbbvwgi6and2fokqess5tojy2u	235	7	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	235	8	D	d	NN
work_dbbvwgi6and2fokqess5tojy2u	235	9	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	235	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	235	11	400	400	CD
work_dbbvwgi6and2fokqess5tojy2u	235	12	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	235	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	235	14	B	B	NNP
work_dbbvwgi6and2fokqess5tojy2u	235	15	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	235	16	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	235	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	235	18	E	E	NNP
work_dbbvwgi6and2fokqess5tojy2u	235	19	-	-	NNP
work_dbbvwgi6and2fokqess5tojy2u	235	20	F	f	NN
work_dbbvwgi6and2fokqess5tojy2u	235	21	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	235	22	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	235	23	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	235	24	30	30	CD
work_dbbvwgi6and2fokqess5tojy2u	235	25	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	235	26	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	235	27	G	G	NNP
work_dbbvwgi6and2fokqess5tojy2u	235	28	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	235	29	H	H	NNP
work_dbbvwgi6and2fokqess5tojy2u	235	30	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	235	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	236	1	Oncotarget56095www.impactjournals.com/oncotarget	oncotarget56095www.impactjournals.com/oncotarget	ADD
work_dbbvwgi6and2fokqess5tojy2u	236	2	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	236	3	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	236	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	236	5	HErc2	HErc2	NNP
work_dbbvwgi6and2fokqess5tojy2u	236	6	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	236	7	present	present	JJ
work_dbbvwgi6and2fokqess5tojy2u	236	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	236	9	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	236	10	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	236	11	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	237	1	Microphotographs	microphotograph	NNS
work_dbbvwgi6and2fokqess5tojy2u	237	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	237	3	coronal	coronal	JJ
work_dbbvwgi6and2fokqess5tojy2u	237	4	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	237	5	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	237	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	237	7	cerebellar	cerebellar	JJ
work_dbbvwgi6and2fokqess5tojy2u	237	8	cortex	cortex	NN
work_dbbvwgi6and2fokqess5tojy2u	237	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	237	10	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	237	11	months	month	NNS
work_dbbvwgi6and2fokqess5tojy2u	237	12	old	old	JJ
work_dbbvwgi6and2fokqess5tojy2u	237	13	Herc2+/+	Herc2+/+	NNP
work_dbbvwgi6and2fokqess5tojy2u	237	14	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	237	15	wt	wt	NNP
work_dbbvwgi6and2fokqess5tojy2u	237	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	237	17	A.-b	A.-b	NNP
work_dbbvwgi6and2fokqess5tojy2u	237	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	237	19	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	238	1	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	238	2	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	238	3	months	month	NNS
work_dbbvwgi6and2fokqess5tojy2u	238	4	old	old	JJ
work_dbbvwgi6and2fokqess5tojy2u	238	5	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	238	6	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	238	7	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	238	8	+	+	NNP
work_dbbvwgi6and2fokqess5tojy2u	238	9	/530	/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	238	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	238	11	D.-E.	d.-e.	XX
work_dbbvwgi6and2fokqess5tojy2u	238	12	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	238	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	239	1	Epifluorescence	epifluorescence	NN
work_dbbvwgi6and2fokqess5tojy2u	239	2	microscopy	microscopy	JJ
work_dbbvwgi6and2fokqess5tojy2u	239	3	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	239	4	shows	show	VBZ
work_dbbvwgi6and2fokqess5tojy2u	239	5	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	239	6	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	239	7	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	239	8	expressed	express	VBN
work_dbbvwgi6and2fokqess5tojy2u	239	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	239	10	all	all	PDT
work_dbbvwgi6and2fokqess5tojy2u	239	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	239	12	adult	adult	NN
work_dbbvwgi6and2fokqess5tojy2u	239	13	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	239	14	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	239	15	colocalizating	colocalizate	VBG
work_dbbvwgi6and2fokqess5tojy2u	239	16	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	239	17	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	239	18	general	general	JJ
work_dbbvwgi6and2fokqess5tojy2u	239	19	marker	marker	NN
work_dbbvwgi6and2fokqess5tojy2u	239	20	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	239	21	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	239	22	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	239	23	calbindin	calbindin	NN
work_dbbvwgi6and2fokqess5tojy2u	239	24	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	239	25	CaBP	CaBP	NNP
work_dbbvwgi6and2fokqess5tojy2u	239	26	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	239	27	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	239	28	A	a	NN
work_dbbvwgi6and2fokqess5tojy2u	239	29	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	239	30	E	e	NN
work_dbbvwgi6and2fokqess5tojy2u	239	31	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	239	32	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	239	33	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	239	34	cerebellar	cerebellar	JJ
work_dbbvwgi6and2fokqess5tojy2u	239	35	cortex	cortex	NN
work_dbbvwgi6and2fokqess5tojy2u	239	36	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	239	37	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	239	38	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	239	39	Cc	Cc	NNP
work_dbbvwgi6and2fokqess5tojy2u	239	40	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	239	41	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	239	42	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	239	43	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	239	44	their	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	239	45	axonal	axonal	JJ
work_dbbvwgi6and2fokqess5tojy2u	239	46	endings	ending	NNS
work_dbbvwgi6and2fokqess5tojy2u	239	47	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	239	48	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	239	49	cerebellar	cerebellar	JJ
work_dbbvwgi6and2fokqess5tojy2u	239	50	nuclei	nuclei	NN
work_dbbvwgi6and2fokqess5tojy2u	239	51	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	239	52	A	a	NN
work_dbbvwgi6and2fokqess5tojy2u	239	53	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	239	54	Cn	Cn	NNP
work_dbbvwgi6and2fokqess5tojy2u	239	55	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	239	56	arrow	arrow	NN
work_dbbvwgi6and2fokqess5tojy2u	239	57	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	239	58	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	240	1	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	240	2	cerebellum	cerebellum	NN
work_dbbvwgi6and2fokqess5tojy2u	240	3	displays	display	VBZ
work_dbbvwgi6and2fokqess5tojy2u	240	4	parasagittal	parasagittal	JJ
work_dbbvwgi6and2fokqess5tojy2u	240	5	bands	band	NNS
work_dbbvwgi6and2fokqess5tojy2u	240	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	240	7	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	240	8	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	240	9	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	240	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	240	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	240	12	vermis	vermis	NNP
work_dbbvwgi6and2fokqess5tojy2u	240	13	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	240	14	paravermal	paravermal	NNP
work_dbbvwgi6and2fokqess5tojy2u	240	15	zones	zone	NNS
work_dbbvwgi6and2fokqess5tojy2u	240	16	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	240	17	c.	c.	NNP
work_dbbvwgi6and2fokqess5tojy2u	240	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	240	19	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	240	20	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	240	21	D	d	NN
work_dbbvwgi6and2fokqess5tojy2u	240	22	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	240	23	arrowheads	arrowhead	NNS
work_dbbvwgi6and2fokqess5tojy2u	240	24	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	240	25	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	240	26	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	240	27	areas	area	NNS
work_dbbvwgi6and2fokqess5tojy2u	240	28	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	240	29	extensive	extensive	JJ
work_dbbvwgi6and2fokqess5tojy2u	240	30	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	240	31	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	240	32	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	240	33	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	240	34	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	240	35	cerebellar	cerebellar	JJ
work_dbbvwgi6and2fokqess5tojy2u	240	36	paraflocculus	paraflocculus	NN
work_dbbvwgi6and2fokqess5tojy2u	240	37	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	240	38	asterisks	asterisks	NNP
work_dbbvwgi6and2fokqess5tojy2u	240	39	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	240	40	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	241	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	241	2	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	241	3	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	241	4	E	e	NN
work_dbbvwgi6and2fokqess5tojy2u	241	5	illustrate	illustrate	VBP
work_dbbvwgi6and2fokqess5tojy2u	241	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	241	7	co	co	NN
work_dbbvwgi6and2fokqess5tojy2u	241	8	-	-	NN
work_dbbvwgi6and2fokqess5tojy2u	241	9	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	241	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	241	11	both	both	DT
work_dbbvwgi6and2fokqess5tojy2u	241	12	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	241	13	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	241	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	241	15	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	241	16	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	241	17	dendritic	dendritic	JJ
work_dbbvwgi6and2fokqess5tojy2u	241	18	tree	tree	NN
work_dbbvwgi6and2fokqess5tojy2u	241	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	242	1	Bars	bar	NNS
work_dbbvwgi6and2fokqess5tojy2u	242	2	=	=	NFP
work_dbbvwgi6and2fokqess5tojy2u	242	3	750	750	CD
work_dbbvwgi6and2fokqess5tojy2u	242	4	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	242	5	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	242	6	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	242	7	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	242	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	242	9	200	200	CD
work_dbbvwgi6and2fokqess5tojy2u	242	10	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	242	11	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	242	12	A	a	NN
work_dbbvwgi6and2fokqess5tojy2u	242	13	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	242	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	242	15	100	100	CD
work_dbbvwgi6and2fokqess5tojy2u	242	16	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	242	17	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	242	18	D	D	NNP
work_dbbvwgi6and2fokqess5tojy2u	242	19	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	242	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	242	21	75	75	CD
work_dbbvwgi6and2fokqess5tojy2u	242	22	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	242	23	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	242	24	E	E	NNP
work_dbbvwgi6and2fokqess5tojy2u	242	25	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	242	26	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	242	27	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	242	28	50	50	CD
work_dbbvwgi6and2fokqess5tojy2u	242	29	µm	µm	FW
work_dbbvwgi6and2fokqess5tojy2u	242	30	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	242	31	B	b	NN
work_dbbvwgi6and2fokqess5tojy2u	242	32	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	242	33	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	243	1	Oncotarget56096www.impactjournals.com/oncotarget	Oncotarget56096www.impactjournals.com/oncotarget	NNP
work_dbbvwgi6and2fokqess5tojy2u	243	2	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	243	3	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	243	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	243	5	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	243	6	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	243	7	degeneration	degeneration	NN
work_dbbvwgi6and2fokqess5tojy2u	243	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	243	9	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	243	10	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	243	11	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	244	1	Microphotographs	microphotograph	NNS
work_dbbvwgi6and2fokqess5tojy2u	244	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	244	3	transmitted	transmit	VBN
work_dbbvwgi6and2fokqess5tojy2u	244	4	light	light	NN
work_dbbvwgi6and2fokqess5tojy2u	244	5	A.-E.	A.-E.	NNP
work_dbbvwgi6and2fokqess5tojy2u	244	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	244	7	electron	electron	NNP
work_dbbvwgi6and2fokqess5tojy2u	244	8	microscopy	microscopy	JJ
work_dbbvwgi6and2fokqess5tojy2u	244	9	F.-H.	F.-H.	NNP
work_dbbvwgi6and2fokqess5tojy2u	244	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	244	11	parasagittal	parasagittal	JJ
work_dbbvwgi6and2fokqess5tojy2u	244	12	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	244	13	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	244	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	244	15	cerebellar	cerebellar	JJ
work_dbbvwgi6and2fokqess5tojy2u	244	16	cortex	cortex	NN
work_dbbvwgi6and2fokqess5tojy2u	244	17	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	244	18	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	244	19	months	month	NNS
work_dbbvwgi6and2fokqess5tojy2u	244	20	Herc2+/+	Herc2+/+	NNS
work_dbbvwgi6and2fokqess5tojy2u	244	21	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	244	22	wt	wt	UH
work_dbbvwgi6and2fokqess5tojy2u	244	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	244	24	A	a	NN
work_dbbvwgi6and2fokqess5tojy2u	244	25	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	244	26	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	244	27	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	244	28	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	244	29	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	244	30	H	h	NN
work_dbbvwgi6and2fokqess5tojy2u	244	31	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	244	32	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	244	33	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	244	34	months	month	NNS
work_dbbvwgi6and2fokqess5tojy2u	244	35	old	old	JJ
work_dbbvwgi6and2fokqess5tojy2u	244	36	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	244	37	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	244	38	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	244	39	+	+	NNP
work_dbbvwgi6and2fokqess5tojy2u	244	40	/530	/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	244	41	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	244	42	b.-G.	b.-g.	ADD
work_dbbvwgi6and2fokqess5tojy2u	244	43	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	244	44	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	245	1	Calbindin	Calbindin	NNP
work_dbbvwgi6and2fokqess5tojy2u	245	2	immunohistochemistry	immunohistochemistry	NN
work_dbbvwgi6and2fokqess5tojy2u	245	3	reveals	reveal	VBZ
work_dbbvwgi6and2fokqess5tojy2u	245	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	245	5	presence	presence	NN
work_dbbvwgi6and2fokqess5tojy2u	245	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	245	7	rounded	rounded	JJ
work_dbbvwgi6and2fokqess5tojy2u	245	8	thickenings	thickening	NNS
work_dbbvwgi6and2fokqess5tojy2u	245	9	resembling	resemble	VBG
work_dbbvwgi6and2fokqess5tojy2u	245	10	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	245	11	axonal	axonal	JJ
work_dbbvwgi6and2fokqess5tojy2u	245	12	torpedoes	torpedo	NNS
work_dbbvwgi6and2fokqess5tojy2u	245	13	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	245	14	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	245	15	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	245	16	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	245	17	axons	axon	NNS
work_dbbvwgi6and2fokqess5tojy2u	245	18	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	245	19	B	B	NNP
work_dbbvwgi6and2fokqess5tojy2u	245	20	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	245	21	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	245	22	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	245	23	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	245	24	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	245	25	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	245	26	which	which	WDT
work_dbbvwgi6and2fokqess5tojy2u	245	27	contrast	contrast	NN
work_dbbvwgi6and2fokqess5tojy2u	245	28	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	245	29	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	245	30	fine	fine	JJ
work_dbbvwgi6and2fokqess5tojy2u	245	31	grained	grain	VBN
work_dbbvwgi6and2fokqess5tojy2u	245	32	morphology	morphology	NN
work_dbbvwgi6and2fokqess5tojy2u	245	33	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	245	34	normal	normal	JJ
work_dbbvwgi6and2fokqess5tojy2u	245	35	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	245	36	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	245	37	axonal	axonal	JJ
work_dbbvwgi6and2fokqess5tojy2u	245	38	plexuses	plexus	NNS
work_dbbvwgi6and2fokqess5tojy2u	245	39	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	245	40	A	a	NN
work_dbbvwgi6and2fokqess5tojy2u	245	41	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	245	42	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	245	43	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	245	44	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	246	1	1.5	1.5	CD
work_dbbvwgi6and2fokqess5tojy2u	246	2	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	246	3	thick	thick	JJ
work_dbbvwgi6and2fokqess5tojy2u	246	4	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	246	5	illustrated	illustrate	VBD
work_dbbvwgi6and2fokqess5tojy2u	246	6	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	246	7	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	246	8	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	246	9	D	d	NN
work_dbbvwgi6and2fokqess5tojy2u	246	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	246	11	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	246	12	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	246	13	limiting	limit	VBG
work_dbbvwgi6and2fokqess5tojy2u	246	14	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	246	15	zone	zone	NN
work_dbbvwgi6and2fokqess5tojy2u	246	16	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	246	17	which	which	WDT
work_dbbvwgi6and2fokqess5tojy2u	246	18	disappeared	disappear	VBD
work_dbbvwgi6and2fokqess5tojy2u	246	19	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	246	20	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	246	21	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	246	22	substituted	substitute	VBN
work_dbbvwgi6and2fokqess5tojy2u	246	23	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	246	24	glial	glial	JJ
work_dbbvwgi6and2fokqess5tojy2u	246	25	Golgi	Golgi	NNP
work_dbbvwgi6and2fokqess5tojy2u	246	26	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	246	27	epithelial	epithelial	JJ
work_dbbvwgi6and2fokqess5tojy2u	246	28	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	246	29	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	246	30	small	small	JJ
work_dbbvwgi6and2fokqess5tojy2u	246	31	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	246	32	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	246	33	D	d	NN
work_dbbvwgi6and2fokqess5tojy2u	246	34	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	246	35	E	e	NN
work_dbbvwgi6and2fokqess5tojy2u	246	36	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	246	37	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	247	1	High	high	JJ
work_dbbvwgi6and2fokqess5tojy2u	247	2	magnification	magnification	NN
work_dbbvwgi6and2fokqess5tojy2u	247	3	allows	allow	VBZ
work_dbbvwgi6and2fokqess5tojy2u	247	4	detect	detect	VB
work_dbbvwgi6and2fokqess5tojy2u	247	5	degenerative	degenerative	JJ
work_dbbvwgi6and2fokqess5tojy2u	247	6	dark	dark	JJ
work_dbbvwgi6and2fokqess5tojy2u	247	7	accumulations	accumulation	NNS
work_dbbvwgi6and2fokqess5tojy2u	247	8	within	within	IN
work_dbbvwgi6and2fokqess5tojy2u	247	9	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	247	10	cytoplasm	cytoplasm	NN
work_dbbvwgi6and2fokqess5tojy2u	247	11	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	247	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	247	13	soma	soma	NN
work_dbbvwgi6and2fokqess5tojy2u	247	14	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	247	15	E	e	NN
work_dbbvwgi6and2fokqess5tojy2u	247	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	247	17	arrowhead	arrowhead	NN
work_dbbvwgi6and2fokqess5tojy2u	247	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	247	19	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	247	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	247	21	dendrites	dendrite	NNS
work_dbbvwgi6and2fokqess5tojy2u	247	22	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	247	23	E	e	NN
work_dbbvwgi6and2fokqess5tojy2u	247	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	247	25	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	247	26	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	247	27	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	247	28	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	247	29	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	247	30	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	247	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	248	1	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	248	2	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	248	3	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	248	4	cytoplasm	cytoplasm	NN
work_dbbvwgi6and2fokqess5tojy2u	248	5	possesses	possesse	NNS
work_dbbvwgi6and2fokqess5tojy2u	248	6	lysosomes	lysosomes	NNP
work_dbbvwgi6and2fokqess5tojy2u	248	7	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	248	8	electron	electron	NN
work_dbbvwgi6and2fokqess5tojy2u	248	9	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	248	10	dense	dense	JJ
work_dbbvwgi6and2fokqess5tojy2u	248	11	debris	debris	NN
work_dbbvwgi6and2fokqess5tojy2u	248	12	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	248	13	F	F	NNP
work_dbbvwgi6and2fokqess5tojy2u	248	14	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	248	15	H	H	NNP
work_dbbvwgi6and2fokqess5tojy2u	248	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	248	17	asterisks	asterisks	RB
work_dbbvwgi6and2fokqess5tojy2u	248	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	248	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	248	20	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	248	21	autophagosomes	autophagosome	VBZ
work_dbbvwgi6and2fokqess5tojy2u	248	22	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	248	23	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	248	24	degrees	degree	NNS
work_dbbvwgi6and2fokqess5tojy2u	248	25	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	248	26	evolution	evolution	NN
work_dbbvwgi6and2fokqess5tojy2u	248	27	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	248	28	G	g	NN
work_dbbvwgi6and2fokqess5tojy2u	248	29	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	248	30	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	248	31	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	248	32	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	249	1	Pcn	Pcn	NNP
work_dbbvwgi6and2fokqess5tojy2u	249	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	249	3	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	249	4	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	249	5	nucleus	nucleus	NN
work_dbbvwgi6and2fokqess5tojy2u	249	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	250	1	Bars	bar	NNS
work_dbbvwgi6and2fokqess5tojy2u	250	2	=	=	NFP
work_dbbvwgi6and2fokqess5tojy2u	250	3	50	50	CD
work_dbbvwgi6and2fokqess5tojy2u	250	4	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	250	5	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	250	6	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	250	7	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	250	8	D	D	NNP
work_dbbvwgi6and2fokqess5tojy2u	250	9	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	250	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	250	11	25	25	CD
work_dbbvwgi6and2fokqess5tojy2u	250	12	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	250	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	250	14	E	E	NNP
work_dbbvwgi6and2fokqess5tojy2u	250	15	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	250	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	250	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	250	18	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	250	19	µm	µm	FW
work_dbbvwgi6and2fokqess5tojy2u	250	20	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	250	21	F	F	NNP
work_dbbvwgi6and2fokqess5tojy2u	250	22	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	250	23	H	H	NNP
work_dbbvwgi6and2fokqess5tojy2u	250	24	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	250	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	251	1	Oncotarget56097www.impactjournals.com/oncotarget	oncotarget56097www.impactjournals.com/oncotarget	ADD
work_dbbvwgi6and2fokqess5tojy2u	251	2	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	251	3	11	11	CD
work_dbbvwgi6and2fokqess5tojy2u	251	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	251	5	Ultrastructural	ultrastructural	JJ
work_dbbvwgi6and2fokqess5tojy2u	251	6	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	251	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	251	8	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	251	9	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	251	10	indicates	indicate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	251	11	accumulation	accumulation	NN
work_dbbvwgi6and2fokqess5tojy2u	251	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	251	13	autophagosomes	autophagosome	NNS
work_dbbvwgi6and2fokqess5tojy2u	251	14	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	251	15	lysosomes	lysosome	NNS
work_dbbvwgi6and2fokqess5tojy2u	251	16	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	251	17	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	251	18	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	251	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	252	1	Electron	Electron	NNP
work_dbbvwgi6and2fokqess5tojy2u	252	2	photomicrographs	photomicrograph	NNS
work_dbbvwgi6and2fokqess5tojy2u	252	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	252	4	parasagittal	parasagittal	JJ
work_dbbvwgi6and2fokqess5tojy2u	252	5	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	252	6	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	252	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	252	8	cerebellar	cerebellar	JJ
work_dbbvwgi6and2fokqess5tojy2u	252	9	vermis	vermi	NNS
work_dbbvwgi6and2fokqess5tojy2u	252	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	252	11	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	252	12	months	month	NNS
work_dbbvwgi6and2fokqess5tojy2u	252	13	old	old	JJ
work_dbbvwgi6and2fokqess5tojy2u	252	14	Herc2+/+	Herc2+/+	NNP
work_dbbvwgi6and2fokqess5tojy2u	252	15	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	252	16	wt	wt	NNP
work_dbbvwgi6and2fokqess5tojy2u	252	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	252	18	A.	A.	NNP
work_dbbvwgi6and2fokqess5tojy2u	252	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	252	20	c.-	c.-	NNP
work_dbbvwgi6and2fokqess5tojy2u	252	21	D.	D.	NNP
work_dbbvwgi6and2fokqess5tojy2u	252	22	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	252	23	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	252	24	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	252	25	months	month	NNS
work_dbbvwgi6and2fokqess5tojy2u	252	26	old	old	JJ
work_dbbvwgi6and2fokqess5tojy2u	252	27	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	252	28	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	252	29	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	252	30	+	+	NNP
work_dbbvwgi6and2fokqess5tojy2u	252	31	/530	/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	252	32	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	252	33	b.	b.	NNP
work_dbbvwgi6and2fokqess5tojy2u	252	34	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	252	35	E.	E.	NNP
work_dbbvwgi6and2fokqess5tojy2u	252	36	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	252	37	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	253	1	An	an	DT
work_dbbvwgi6and2fokqess5tojy2u	253	2	important	important	JJ
work_dbbvwgi6and2fokqess5tojy2u	253	3	difference	difference	NN
work_dbbvwgi6and2fokqess5tojy2u	253	4	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	253	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	253	6	presence	presence	NN
work_dbbvwgi6and2fokqess5tojy2u	253	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	253	8	autophagic	autophagic	JJ
work_dbbvwgi6and2fokqess5tojy2u	253	9	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	253	10	arrowheads	arrowhead	NNS
work_dbbvwgi6and2fokqess5tojy2u	253	11	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	253	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	253	13	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	253	14	lysosomal	lysosomal	NN
work_dbbvwgi6and2fokqess5tojy2u	253	15	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	253	16	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	253	17	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	253	18	organelles	organelle	NNS
work_dbbvwgi6and2fokqess5tojy2u	253	19	can	can	MD
work_dbbvwgi6and2fokqess5tojy2u	253	20	be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	253	21	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	253	22	between	between	IN
work_dbbvwgi6and2fokqess5tojy2u	253	23	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	253	24	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	253	25	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	253	26	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	253	27	A	a	NN
work_dbbvwgi6and2fokqess5tojy2u	253	28	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	253	29	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	253	30	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	253	31	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	253	32	B	B	NNP
work_dbbvwgi6and2fokqess5tojy2u	253	33	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	253	34	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	253	35	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	253	36	cytoplasm	cytoplasm	VBP
work_dbbvwgi6and2fokqess5tojy2u	253	37	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	254	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	254	2	difference	difference	NN
work_dbbvwgi6and2fokqess5tojy2u	254	3	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	254	4	even	even	RB
work_dbbvwgi6and2fokqess5tojy2u	254	5	most	most	RBS
work_dbbvwgi6and2fokqess5tojy2u	254	6	evident	evident	JJ
work_dbbvwgi6and2fokqess5tojy2u	254	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	254	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	254	9	principal	principal	JJ
work_dbbvwgi6and2fokqess5tojy2u	254	10	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	254	11	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	254	12	dendrites	dendrite	NNS
work_dbbvwgi6and2fokqess5tojy2u	254	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	255	1	Thus	thus	RB
work_dbbvwgi6and2fokqess5tojy2u	255	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	255	3	numerous	numerous	JJ
work_dbbvwgi6and2fokqess5tojy2u	255	4	degenerative	degenerative	JJ
work_dbbvwgi6and2fokqess5tojy2u	255	5	signs	sign	NNS
work_dbbvwgi6and2fokqess5tojy2u	255	6	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	255	7	present	present	JJ
work_dbbvwgi6and2fokqess5tojy2u	255	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	255	9	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	255	10	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	255	11	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	255	12	dendrite	dendrite	VBP
work_dbbvwgi6and2fokqess5tojy2u	255	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	255	14	E	e	NN
work_dbbvwgi6and2fokqess5tojy2u	255	15	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	255	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	255	17	while	while	IN
work_dbbvwgi6and2fokqess5tojy2u	255	18	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	255	19	almost	almost	RB
work_dbbvwgi6and2fokqess5tojy2u	255	20	absent	absent	JJ
work_dbbvwgi6and2fokqess5tojy2u	255	21	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	255	22	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	255	23	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	255	24	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	255	25	ones	one	NNS
work_dbbvwgi6and2fokqess5tojy2u	255	26	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	255	27	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	255	28	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	255	29	D	D	NNP
work_dbbvwgi6and2fokqess5tojy2u	255	30	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	255	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	256	1	Pcd	Pcd	NNP
work_dbbvwgi6and2fokqess5tojy2u	256	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	256	3	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	256	4	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	256	5	dendrite	dendrite	NN
work_dbbvwgi6and2fokqess5tojy2u	256	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	257	1	Pcn	Pcn	NNP
work_dbbvwgi6and2fokqess5tojy2u	257	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	257	3	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	257	4	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	257	5	nucleus	nucleus	NN
work_dbbvwgi6and2fokqess5tojy2u	257	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	258	1	Bars	bar	NNS
work_dbbvwgi6and2fokqess5tojy2u	258	2	=	=	SYM
work_dbbvwgi6and2fokqess5tojy2u	258	3	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	258	4	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	258	5	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	258	6	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	258	7	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	258	8	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	258	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	258	10	E	E	NNP
work_dbbvwgi6and2fokqess5tojy2u	258	11	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	258	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	258	13	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	258	14	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	258	15	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	258	16	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	258	17	D	D	NNP
work_dbbvwgi6and2fokqess5tojy2u	258	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	258	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	259	1	Oncotarget56098www.impactjournals.com/oncotarget	Oncotarget56098www.impactjournals.com/oncotarget	NFP
work_dbbvwgi6and2fokqess5tojy2u	259	2	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	259	3	findings	finding	NNS
work_dbbvwgi6and2fokqess5tojy2u	259	4	suggest	suggest	VBP
work_dbbvwgi6and2fokqess5tojy2u	259	5	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	259	6	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	259	7	plays	play	VBZ
work_dbbvwgi6and2fokqess5tojy2u	259	8	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	259	9	active	active	JJ
work_dbbvwgi6and2fokqess5tojy2u	259	10	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	259	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	259	12	regulating	regulate	VBG
work_dbbvwgi6and2fokqess5tojy2u	259	13	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	259	14	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	259	15	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	259	16	homeostasis	homeostasis	NN
work_dbbvwgi6and2fokqess5tojy2u	259	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	259	18	whose	whose	WP$
work_dbbvwgi6and2fokqess5tojy2u	259	19	deregulation	deregulation	NN
work_dbbvwgi6and2fokqess5tojy2u	259	20	elicits	elicit	VBZ
work_dbbvwgi6and2fokqess5tojy2u	259	21	alterations	alteration	NNS
work_dbbvwgi6and2fokqess5tojy2u	259	22	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	259	23	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	259	24	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	259	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	260	1	DIscUssION	DIscUssION	NNP
work_dbbvwgi6and2fokqess5tojy2u	260	2	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	260	3	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	260	4	generated	generate	VBN
work_dbbvwgi6and2fokqess5tojy2u	260	5	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	260	6	new	new	JJ
work_dbbvwgi6and2fokqess5tojy2u	260	7	mutant	mutant	JJ
work_dbbvwgi6and2fokqess5tojy2u	260	8	allele	allele	NN
work_dbbvwgi6and2fokqess5tojy2u	260	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	260	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	260	11	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	260	12	ubiquitin	ubiquitin	NNP
work_dbbvwgi6and2fokqess5tojy2u	260	13	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	260	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	260	15	Herc2530	Herc2530	NNP
work_dbbvwgi6and2fokqess5tojy2u	260	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	260	17	which	which	WDT
work_dbbvwgi6and2fokqess5tojy2u	260	18	has	have	VBZ
work_dbbvwgi6and2fokqess5tojy2u	260	19	led	lead	VBN
work_dbbvwgi6and2fokqess5tojy2u	260	20	us	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	260	21	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	260	22	identify	identify	VB
work_dbbvwgi6and2fokqess5tojy2u	260	23	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	260	24	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	260	25	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	260	26	essential	essential	JJ
work_dbbvwgi6and2fokqess5tojy2u	260	27	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	260	28	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	260	29	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	260	30	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	260	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	261	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	261	2	HERC2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	261	3	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	261	4	encodes	encode	VBZ
work_dbbvwgi6and2fokqess5tojy2u	261	5	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	261	6	unusual	unusual	JJ
work_dbbvwgi6and2fokqess5tojy2u	261	7	long	long	JJ
work_dbbvwgi6and2fokqess5tojy2u	261	8	polypeptide	polypeptide	NN
work_dbbvwgi6and2fokqess5tojy2u	261	9	chain	chain	NN
work_dbbvwgi6and2fokqess5tojy2u	261	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	261	11	almost	almost	RB
work_dbbvwgi6and2fokqess5tojy2u	261	12	5,000	5,000	CD
work_dbbvwgi6and2fokqess5tojy2u	261	13	amino	amino	JJ
work_dbbvwgi6and2fokqess5tojy2u	261	14	acid	acid	NN
work_dbbvwgi6and2fokqess5tojy2u	261	15	residues	residue	NNS
work_dbbvwgi6and2fokqess5tojy2u	261	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	262	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	262	2	maintenance	maintenance	NN
work_dbbvwgi6and2fokqess5tojy2u	262	3	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	262	4	evolution	evolution	NN
work_dbbvwgi6and2fokqess5tojy2u	262	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	262	6	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	262	7	single	single	JJ
work_dbbvwgi6and2fokqess5tojy2u	262	8	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	262	9	long	long	JJ
work_dbbvwgi6and2fokqess5tojy2u	262	10	polypeptide	polypeptide	NN
work_dbbvwgi6and2fokqess5tojy2u	262	11	chain	chain	NN
work_dbbvwgi6and2fokqess5tojy2u	262	12	suggests	suggest	VBZ
work_dbbvwgi6and2fokqess5tojy2u	262	13	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	262	14	important	important	JJ
work_dbbvwgi6and2fokqess5tojy2u	262	15	physiological	physiological	JJ
work_dbbvwgi6and2fokqess5tojy2u	262	16	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	262	17	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	262	18	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	262	19	giant	giant	JJ
work_dbbvwgi6and2fokqess5tojy2u	262	20	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	262	21	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	262	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	263	1	Here	here	RB
work_dbbvwgi6and2fokqess5tojy2u	263	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	263	3	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	263	4	showed	show	VBD
work_dbbvwgi6and2fokqess5tojy2u	263	5	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	263	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	263	7	inactivation	inactivation	NN
work_dbbvwgi6and2fokqess5tojy2u	263	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	263	9	Herc2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	263	10	causes	cause	VBZ
work_dbbvwgi6and2fokqess5tojy2u	263	11	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	263	12	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	263	13	before	before	IN
work_dbbvwgi6and2fokqess5tojy2u	263	14	7.5	7.5	CD
work_dbbvwgi6and2fokqess5tojy2u	263	15	days	day	NNS
work_dbbvwgi6and2fokqess5tojy2u	263	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	264	1	At	at	IN
work_dbbvwgi6and2fokqess5tojy2u	264	2	that	that	DT
work_dbbvwgi6and2fokqess5tojy2u	264	3	time	time	NN
work_dbbvwgi6and2fokqess5tojy2u	264	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	264	5	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	264	6	observed	observe	VBD
work_dbbvwgi6and2fokqess5tojy2u	264	7	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	264	8	high	high	JJ
work_dbbvwgi6and2fokqess5tojy2u	264	9	number	number	NN
work_dbbvwgi6and2fokqess5tojy2u	264	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	264	11	abnormal	abnormal	JJ
work_dbbvwgi6and2fokqess5tojy2u	264	12	placentas	placenta	NNS
work_dbbvwgi6and2fokqess5tojy2u	264	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	264	14	probably	probably	RB
work_dbbvwgi6and2fokqess5tojy2u	264	15	indicating	indicate	VBG
work_dbbvwgi6and2fokqess5tojy2u	264	16	resorption	resorption	NN
work_dbbvwgi6and2fokqess5tojy2u	264	17	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	264	18	unviable	unviable	JJ
work_dbbvwgi6and2fokqess5tojy2u	264	19	embryos	embryo	NNS
work_dbbvwgi6and2fokqess5tojy2u	264	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	265	1	Although	although	IN
work_dbbvwgi6and2fokqess5tojy2u	265	2	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	265	3	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	265	4	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	265	5	studied	study	VBN
work_dbbvwgi6and2fokqess5tojy2u	265	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	265	7	cause	cause	NN
work_dbbvwgi6and2fokqess5tojy2u	265	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	265	9	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	265	10	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	265	11	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	265	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	265	13	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	265	14	possibility	possibility	NN
work_dbbvwgi6and2fokqess5tojy2u	265	15	could	could	MD
work_dbbvwgi6and2fokqess5tojy2u	265	16	be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	265	17	defective	defective	JJ
work_dbbvwgi6and2fokqess5tojy2u	265	18	implantation	implantation	NN
work_dbbvwgi6and2fokqess5tojy2u	265	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	266	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	266	2	unviability	unviability	NN
work_dbbvwgi6and2fokqess5tojy2u	266	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	266	4	embryos	embryo	NNS
work_dbbvwgi6and2fokqess5tojy2u	266	5	when	when	WRB
work_dbbvwgi6and2fokqess5tojy2u	266	6	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	266	7	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	266	8	inactivated	inactivate	VBN
work_dbbvwgi6and2fokqess5tojy2u	266	9	would	would	MD
work_dbbvwgi6and2fokqess5tojy2u	266	10	be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	266	11	indicative	indicative	JJ
work_dbbvwgi6and2fokqess5tojy2u	266	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	266	13	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	266	14	difficulty	difficulty	NN
work_dbbvwgi6and2fokqess5tojy2u	266	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	266	16	finding	find	VBG
work_dbbvwgi6and2fokqess5tojy2u	266	17	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	266	18	individuals	individual	NNS
work_dbbvwgi6and2fokqess5tojy2u	266	19	homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	266	20	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	266	21	mutations	mutation	NNS
work_dbbvwgi6and2fokqess5tojy2u	266	22	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	266	23	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	266	24	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	266	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	267	1	To	to	IN
work_dbbvwgi6and2fokqess5tojy2u	267	2	our	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	267	3	knowledge	knowledge	NN
work_dbbvwgi6and2fokqess5tojy2u	267	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	267	5	only	only	RB
work_dbbvwgi6and2fokqess5tojy2u	267	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	267	7	HERC2P594L	HERC2P594L	NNP
work_dbbvwgi6and2fokqess5tojy2u	267	8	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	267	9	found	find	VBN
work_dbbvwgi6and2fokqess5tojy2u	267	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	267	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	267	12	Amish	amish	JJ
work_dbbvwgi6and2fokqess5tojy2u	267	13	community	community	NN
work_dbbvwgi6and2fokqess5tojy2u	267	14	has	have	VBZ
work_dbbvwgi6and2fokqess5tojy2u	267	15	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	267	16	reported	report	VBN
work_dbbvwgi6and2fokqess5tojy2u	267	17	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	267	18	humans	human	NNS
work_dbbvwgi6and2fokqess5tojy2u	267	19	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	267	20	45	45	CD
work_dbbvwgi6and2fokqess5tojy2u	267	21	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	267	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	268	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	268	2	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	268	3	individuals	individual	NNS
work_dbbvwgi6and2fokqess5tojy2u	268	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	268	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	268	6	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	268	7	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	268	8	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	268	9	unstable	unstable	JJ
work_dbbvwgi6and2fokqess5tojy2u	268	10	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	268	11	low	low	JJ
work_dbbvwgi6and2fokqess5tojy2u	268	12	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	268	13	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	268	14	detected	detect	VBN
work_dbbvwgi6and2fokqess5tojy2u	268	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	268	16	although	although	IN
work_dbbvwgi6and2fokqess5tojy2u	268	17	apparently	apparently	RB
work_dbbvwgi6and2fokqess5tojy2u	268	18	high	high	JJ
work_dbbvwgi6and2fokqess5tojy2u	268	19	enough	enough	RB
work_dbbvwgi6and2fokqess5tojy2u	268	20	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	268	21	avoid	avoid	VB
work_dbbvwgi6and2fokqess5tojy2u	268	22	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	268	23	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	268	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	269	1	Ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	269	2	ligases	ligase	NNS
work_dbbvwgi6and2fokqess5tojy2u	269	3	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	269	4	interact	interact	VBP
work_dbbvwgi6and2fokqess5tojy2u	269	5	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	269	6	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	269	7	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	269	8	such	such	JJ
work_dbbvwgi6and2fokqess5tojy2u	269	9	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	269	10	MDM2	MDM2	NNP
work_dbbvwgi6and2fokqess5tojy2u	269	11	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	269	12	MDM4	MDM4	NNP
work_dbbvwgi6and2fokqess5tojy2u	269	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	269	14	had	have	VBD
work_dbbvwgi6and2fokqess5tojy2u	269	15	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	269	16	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	269	17	identified	identify	VBN
work_dbbvwgi6and2fokqess5tojy2u	269	18	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	269	19	essential	essential	JJ
work_dbbvwgi6and2fokqess5tojy2u	269	20	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	269	21	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	269	22	phases	phase	NNS
work_dbbvwgi6and2fokqess5tojy2u	269	23	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	270	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	270	2	absence	absence	NN
work_dbbvwgi6and2fokqess5tojy2u	270	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	270	4	MDM2	MDM2	NNP
work_dbbvwgi6and2fokqess5tojy2u	270	5	induces	induce	VBZ
work_dbbvwgi6and2fokqess5tojy2u	270	6	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	270	7	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	270	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	270	9	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	270	10	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	270	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	270	12	peri	peri	NN
work_dbbvwgi6and2fokqess5tojy2u	270	13	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	270	14	implantation	implantation	NN
work_dbbvwgi6and2fokqess5tojy2u	270	15	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	270	16	E4-E5.5	e4-e5.5	NN
work_dbbvwgi6and2fokqess5tojy2u	270	17	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	270	18	stage	stage	NN
work_dbbvwgi6and2fokqess5tojy2u	270	19	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	270	20	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	270	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	270	22	whereas	whereas	IN
work_dbbvwgi6and2fokqess5tojy2u	270	23	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	270	24	deficient	deficient	JJ
work_dbbvwgi6and2fokqess5tojy2u	270	25	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	270	26	MDM4	MDM4	NNP
work_dbbvwgi6and2fokqess5tojy2u	270	27	die	die	VBP
work_dbbvwgi6and2fokqess5tojy2u	270	28	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	270	29	mid	mid	NN
work_dbbvwgi6and2fokqess5tojy2u	270	30	-	-	NN
work_dbbvwgi6and2fokqess5tojy2u	270	31	gestation	gestation	NN
work_dbbvwgi6and2fokqess5tojy2u	270	32	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	270	33	E7.5-E8.5	E7.5-E8.5	NNP
work_dbbvwgi6and2fokqess5tojy2u	270	34	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	270	35	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	270	36	33	33	CD
work_dbbvwgi6and2fokqess5tojy2u	270	37	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	270	38	35	35	CD
work_dbbvwgi6and2fokqess5tojy2u	270	39	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	270	40	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	271	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	271	2	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	271	3	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	271	4	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	271	5	phases	phase	NNS
work_dbbvwgi6and2fokqess5tojy2u	271	6	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	271	7	rescued	rescue	VBN
work_dbbvwgi6and2fokqess5tojy2u	271	8	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	271	9	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	271	10	double	double	JJ
work_dbbvwgi6and2fokqess5tojy2u	271	11	knockout	knockout	NN
work_dbbvwgi6and2fokqess5tojy2u	271	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	271	13	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	271	14	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	271	15	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	271	16	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	271	17	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	271	18	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	271	19	33	33	CD
work_dbbvwgi6and2fokqess5tojy2u	271	20	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	271	21	35	35	CD
work_dbbvwgi6and2fokqess5tojy2u	271	22	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	271	23	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	272	1	Because	because	IN
work_dbbvwgi6and2fokqess5tojy2u	272	2	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	272	3	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	272	4	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	272	5	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	272	6	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	272	7	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	272	8	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	272	9	interacts	interact	VBZ
work_dbbvwgi6and2fokqess5tojy2u	272	10	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	272	11	regulates	regulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	272	12	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	272	13	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	272	14	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	272	15	32	32	CD
work_dbbvwgi6and2fokqess5tojy2u	272	16	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	272	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	272	18	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	272	19	analyzed	analyze	VBD
work_dbbvwgi6and2fokqess5tojy2u	272	20	whether	whether	IN
work_dbbvwgi6and2fokqess5tojy2u	272	21	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	272	22	double	double	JJ
work_dbbvwgi6and2fokqess5tojy2u	272	23	knockout	knockout	NN
work_dbbvwgi6and2fokqess5tojy2u	272	24	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	272	25	HERC2	herc2	NN
work_dbbvwgi6and2fokqess5tojy2u	272	26	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	272	27	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	272	28	could	could	MD
work_dbbvwgi6and2fokqess5tojy2u	272	29	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	272	30	rescue	rescue	VB
work_dbbvwgi6and2fokqess5tojy2u	272	31	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	272	32	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	272	33	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	273	1	Our	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	273	2	results	result	NNS
work_dbbvwgi6and2fokqess5tojy2u	273	3	show	show	VBP
work_dbbvwgi6and2fokqess5tojy2u	273	4	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	273	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	273	6	double	double	JJ
work_dbbvwgi6and2fokqess5tojy2u	273	7	knockout	knockout	NN
work_dbbvwgi6and2fokqess5tojy2u	273	8	did	do	VBD
work_dbbvwgi6and2fokqess5tojy2u	273	9	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	273	10	rescue	rescue	VB
work_dbbvwgi6and2fokqess5tojy2u	273	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	273	12	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	273	13	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	273	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	273	15	indicating	indicate	VBG
work_dbbvwgi6and2fokqess5tojy2u	273	16	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	273	17	p53-independent	p53-independent	JJ
work_dbbvwgi6and2fokqess5tojy2u	273	18	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	273	19	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	273	20	HERC2	herc2	NN
work_dbbvwgi6and2fokqess5tojy2u	273	21	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	273	22	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	273	23	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	274	1	Moreover	moreover	RB
work_dbbvwgi6and2fokqess5tojy2u	274	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	274	3	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	274	4	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	274	5	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	274	6	confirm	confirm	VBP
work_dbbvwgi6and2fokqess5tojy2u	274	7	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	274	8	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	274	9	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	274	10	genetic	genetic	JJ
work_dbbvwgi6and2fokqess5tojy2u	274	11	level	level	NN
work_dbbvwgi6and2fokqess5tojy2u	274	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	274	13	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	274	14	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	274	15	functions	function	NNS
work_dbbvwgi6and2fokqess5tojy2u	274	16	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	274	17	MDM2	MDM2	NNP
work_dbbvwgi6and2fokqess5tojy2u	274	18	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	274	19	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	274	20	MDM4	MDM4	NNP
work_dbbvwgi6and2fokqess5tojy2u	274	21	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	274	22	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	274	23	HERC2	herc2	NN
work_dbbvwgi6and2fokqess5tojy2u	274	24	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	274	25	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	274	26	regulation	regulation	NN
work_dbbvwgi6and2fokqess5tojy2u	274	27	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	275	1	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	275	2	acts	act	VBZ
work_dbbvwgi6and2fokqess5tojy2u	275	3	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	275	4	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	275	5	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	275	6	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	275	7	tagging	tag	VBG
work_dbbvwgi6and2fokqess5tojy2u	275	8	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	275	9	degradation	degradation	NN
work_dbbvwgi6and2fokqess5tojy2u	275	10	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	275	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	275	12	proteasome	proteasome	NN
work_dbbvwgi6and2fokqess5tojy2u	275	13	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	275	14	substrates	substrate	NNS
work_dbbvwgi6and2fokqess5tojy2u	275	15	such	such	JJ
work_dbbvwgi6and2fokqess5tojy2u	275	16	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	275	17	XPA	XPA	NNP
work_dbbvwgi6and2fokqess5tojy2u	275	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	275	19	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	275	20	12	12	CD
work_dbbvwgi6and2fokqess5tojy2u	275	21	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	275	22	p62	p62	NN
work_dbbvwgi6and2fokqess5tojy2u	275	23	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	275	24	sQstM1	sQstM1	NNP
work_dbbvwgi6and2fokqess5tojy2u	275	25	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	275	26	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	275	27	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	275	28	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	276	1	Laser	Laser	NNP
work_dbbvwgi6and2fokqess5tojy2u	276	2	confocal	confocal	JJ
work_dbbvwgi6and2fokqess5tojy2u	276	3	microphotographs	microphotograph	NNS
work_dbbvwgi6and2fokqess5tojy2u	276	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	276	5	coronal	coronal	JJ
work_dbbvwgi6and2fokqess5tojy2u	276	6	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	276	7	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	276	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	276	9	cerebellar	cerebellar	JJ
work_dbbvwgi6and2fokqess5tojy2u	276	10	cortex	cortex	NN
work_dbbvwgi6and2fokqess5tojy2u	276	11	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	276	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	276	13	vermis	vermi	NNS
work_dbbvwgi6and2fokqess5tojy2u	276	14	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	276	15	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	276	16	months	month	NNS
work_dbbvwgi6and2fokqess5tojy2u	276	17	Herc2+/+	Herc2+/+	NNS
work_dbbvwgi6and2fokqess5tojy2u	276	18	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	276	19	wt	wt	UH
work_dbbvwgi6and2fokqess5tojy2u	276	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	276	21	A	a	NN
work_dbbvwgi6and2fokqess5tojy2u	276	22	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	276	23	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	276	24	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	276	25	months	month	NNS
work_dbbvwgi6and2fokqess5tojy2u	276	26	old	old	JJ
work_dbbvwgi6and2fokqess5tojy2u	276	27	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	276	28	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	276	29	+	+	NNP
work_dbbvwgi6and2fokqess5tojy2u	276	30	/530	/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	276	31	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	276	32	B	b	NN
work_dbbvwgi6and2fokqess5tojy2u	276	33	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	276	34	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	276	35	double	double	JJ
work_dbbvwgi6and2fokqess5tojy2u	276	36	labeled	label	VBN
work_dbbvwgi6and2fokqess5tojy2u	276	37	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	276	38	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	276	39	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	276	40	p62	p62	NN
work_dbbvwgi6and2fokqess5tojy2u	276	41	antibodies	antibody	NNS
work_dbbvwgi6and2fokqess5tojy2u	276	42	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	277	1	Colocalizations	colocalization	NNS
work_dbbvwgi6and2fokqess5tojy2u	277	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	277	3	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	277	4	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	277	5	p62	p62	NN
work_dbbvwgi6and2fokqess5tojy2u	277	6	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	277	7	indicated	indicate	VBN
work_dbbvwgi6and2fokqess5tojy2u	277	8	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	277	9	arrows	arrow	NNS
work_dbbvwgi6and2fokqess5tojy2u	277	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	277	11	dendrites	dendrite	NNS
work_dbbvwgi6and2fokqess5tojy2u	277	12	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	277	13	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	277	14	somata	somata	NNP
work_dbbvwgi6and2fokqess5tojy2u	277	15	A.	A.	NNP
work_dbbvwgi6and2fokqess5tojy2u	277	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	277	17	b.	b.	NNP
work_dbbvwgi6and2fokqess5tojy2u	277	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	277	19	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	277	20	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	277	21	arrowheads	arrowhead	NNS
work_dbbvwgi6and2fokqess5tojy2u	277	22	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	277	23	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	277	24	axonal	axonal	JJ
work_dbbvwgi6and2fokqess5tojy2u	277	25	torpedoes	torpedo	NNS
work_dbbvwgi6and2fokqess5tojy2u	277	26	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	277	27	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	277	28	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	277	29	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	277	30	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	277	31	B	b	NN
work_dbbvwgi6and2fokqess5tojy2u	277	32	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	277	33	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	278	1	Asterisks	asterisk	NNS
work_dbbvwgi6and2fokqess5tojy2u	278	2	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	278	3	B	b	NN
work_dbbvwgi6and2fokqess5tojy2u	278	4	indicate	indicate	VBP
work_dbbvwgi6and2fokqess5tojy2u	278	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	278	6	absence	absence	NN
work_dbbvwgi6and2fokqess5tojy2u	278	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	278	8	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	278	9	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	278	10	bodies	body	NNS
work_dbbvwgi6and2fokqess5tojy2u	278	11	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	279	1	Bar	bar	NN
work_dbbvwgi6and2fokqess5tojy2u	279	2	=	=	SYM
work_dbbvwgi6and2fokqess5tojy2u	279	3	50	50	CD
work_dbbvwgi6and2fokqess5tojy2u	279	4	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	279	5	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	279	6	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	279	7	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	279	8	B	b	NN
work_dbbvwgi6and2fokqess5tojy2u	279	9	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	279	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	280	1	Oncotarget56099www.impactjournals.com/oncotarget	oncotarget56099www.impactjournals.com/oncotarget	ADD
work_dbbvwgi6and2fokqess5tojy2u	280	2	BRCA1	BRCA1	NNP
work_dbbvwgi6and2fokqess5tojy2u	280	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	280	4	NEURL4	NEURL4	NNP
work_dbbvwgi6and2fokqess5tojy2u	280	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	280	6	FBXL5	fbxl5	NN
work_dbbvwgi6and2fokqess5tojy2u	280	7	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	280	8	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	280	9	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	280	10	21	21	CD
work_dbbvwgi6and2fokqess5tojy2u	280	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	280	12	22	22	CD
work_dbbvwgi6and2fokqess5tojy2u	280	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	280	14	24	24	CD
work_dbbvwgi6and2fokqess5tojy2u	280	15	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	280	16	26	26	CD
work_dbbvwgi6and2fokqess5tojy2u	280	17	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	280	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	281	1	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	281	2	may	may	MD
work_dbbvwgi6and2fokqess5tojy2u	281	3	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	281	4	positively	positively	RB
work_dbbvwgi6and2fokqess5tojy2u	281	5	regulate	regulate	VB
work_dbbvwgi6and2fokqess5tojy2u	281	6	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	281	7	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	281	8	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	281	9	stimulation	stimulation	NN
work_dbbvwgi6and2fokqess5tojy2u	281	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	281	11	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	281	12	oligomerization	oligomerization	NN
work_dbbvwgi6and2fokqess5tojy2u	281	13	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	281	14	32	32	CD
work_dbbvwgi6and2fokqess5tojy2u	281	15	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	281	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	282	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	282	2	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	282	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	282	4	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	282	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	282	6	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	282	7	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	282	8	p21	p21	NNP
work_dbbvwgi6and2fokqess5tojy2u	282	9	led	lead	VBD
work_dbbvwgi6and2fokqess5tojy2u	282	10	us	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	282	11	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	282	12	analyze	analyze	VB
work_dbbvwgi6and2fokqess5tojy2u	282	13	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	282	14	two	two	CD
work_dbbvwgi6and2fokqess5tojy2u	282	15	activities	activity	NNS
work_dbbvwgi6and2fokqess5tojy2u	282	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	282	17	respectively	respectively	RB
work_dbbvwgi6and2fokqess5tojy2u	282	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	283	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	283	2	activities	activity	NNS
work_dbbvwgi6and2fokqess5tojy2u	283	3	had	have	VBD
work_dbbvwgi6and2fokqess5tojy2u	283	4	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	283	5	reported	report	VBN
work_dbbvwgi6and2fokqess5tojy2u	283	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	283	7	culture	culture	NN
work_dbbvwgi6and2fokqess5tojy2u	283	8	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	283	9	but	but	CC
work_dbbvwgi6and2fokqess5tojy2u	283	10	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	283	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	283	12	physiological	physiological	JJ
work_dbbvwgi6and2fokqess5tojy2u	283	13	conditions	condition	NNS
work_dbbvwgi6and2fokqess5tojy2u	283	14	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	284	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	284	2	generation	generation	NN
work_dbbvwgi6and2fokqess5tojy2u	284	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	284	4	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	284	5	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	284	6	containing	contain	VBG
work_dbbvwgi6and2fokqess5tojy2u	284	7	approximately	approximately	RB
work_dbbvwgi6and2fokqess5tojy2u	284	8	one	one	CD
work_dbbvwgi6and2fokqess5tojy2u	284	9	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	284	10	half	half	NN
work_dbbvwgi6and2fokqess5tojy2u	284	11	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	284	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	284	13	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	284	14	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	284	15	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	284	16	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	284	17	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	284	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	284	19	led	lead	VBD
work_dbbvwgi6and2fokqess5tojy2u	284	20	us	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	284	21	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	284	22	analyze	analyze	VB
work_dbbvwgi6and2fokqess5tojy2u	284	23	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	284	24	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	284	25	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	284	26	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	284	27	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	284	28	vivo	vivo	NNP
work_dbbvwgi6and2fokqess5tojy2u	284	29	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	285	1	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	285	2	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	285	3	had	have	VBD
work_dbbvwgi6and2fokqess5tojy2u	285	4	higher	high	JJR
work_dbbvwgi6and2fokqess5tojy2u	285	5	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	285	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	285	7	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	285	8	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	285	9	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	285	10	lower	low	JJR
work_dbbvwgi6and2fokqess5tojy2u	285	11	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	285	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	285	13	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	285	14	mRNA	mRNA	NNS
work_dbbvwgi6and2fokqess5tojy2u	285	15	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	285	16	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	285	17	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	285	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	285	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	286	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	286	2	results	result	NNS
work_dbbvwgi6and2fokqess5tojy2u	286	3	show	show	VBP
work_dbbvwgi6and2fokqess5tojy2u	286	4	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	286	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	286	6	first	first	JJ
work_dbbvwgi6and2fokqess5tojy2u	286	7	time	time	NN
work_dbbvwgi6and2fokqess5tojy2u	286	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	286	9	inhibition	inhibition	NN
work_dbbvwgi6and2fokqess5tojy2u	286	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	286	11	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	286	12	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	286	13	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	286	14	physiological	physiological	JJ
work_dbbvwgi6and2fokqess5tojy2u	286	15	conditions	condition	NNS
work_dbbvwgi6and2fokqess5tojy2u	286	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	287	1	Individuals	individual	NNS
work_dbbvwgi6and2fokqess5tojy2u	287	2	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	287	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	287	4	Amish	amish	JJ
work_dbbvwgi6and2fokqess5tojy2u	287	5	community	community	NN
work_dbbvwgi6and2fokqess5tojy2u	287	6	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	287	7	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	287	8	punctual	punctual	JJ
work_dbbvwgi6and2fokqess5tojy2u	287	9	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	287	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	287	11	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	287	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	287	13	HERC2P594L	HERC2P594L	NNP
work_dbbvwgi6and2fokqess5tojy2u	287	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	287	15	suffer	suffer	VBP
work_dbbvwgi6and2fokqess5tojy2u	287	16	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	287	17	developmental	developmental	JJ
work_dbbvwgi6and2fokqess5tojy2u	287	18	disorder	disorder	NN
work_dbbvwgi6and2fokqess5tojy2u	287	19	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	287	20	features	feature	NNS
work_dbbvwgi6and2fokqess5tojy2u	287	21	similar	similar	JJ
work_dbbvwgi6and2fokqess5tojy2u	287	22	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	287	23	Angelman	Angelman	NNP
work_dbbvwgi6and2fokqess5tojy2u	287	24	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	287	25	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	287	26	4,5	4,5	CD
work_dbbvwgi6and2fokqess5tojy2u	287	27	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	287	28	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	288	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	288	2	individuals	individual	NNS
work_dbbvwgi6and2fokqess5tojy2u	288	3	produce	produce	VBP
work_dbbvwgi6and2fokqess5tojy2u	288	4	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	288	5	instable	instable	JJ
work_dbbvwgi6and2fokqess5tojy2u	288	6	HERC2P594L	HERC2P594L	NNP
work_dbbvwgi6and2fokqess5tojy2u	288	7	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	288	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	289	1	Skin	skin	NN
work_dbbvwgi6and2fokqess5tojy2u	289	2	fibroblasts	fibroblast	NNS
work_dbbvwgi6and2fokqess5tojy2u	289	3	obtained	obtain	VBN
work_dbbvwgi6and2fokqess5tojy2u	289	4	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	289	5	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	289	6	individuals	individual	NNS
work_dbbvwgi6and2fokqess5tojy2u	289	7	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	289	8	had	have	VBD
work_dbbvwgi6and2fokqess5tojy2u	289	9	higher	high	JJR
work_dbbvwgi6and2fokqess5tojy2u	289	10	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	289	11	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	289	12	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	289	13	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	289	14	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	289	15	lower	low	JJR
work_dbbvwgi6and2fokqess5tojy2u	289	16	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	289	17	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	289	18	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	289	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	289	20	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	289	21	agreement	agreement	NN
work_dbbvwgi6and2fokqess5tojy2u	289	22	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	289	23	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	289	24	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	289	25	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	289	26	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	289	27	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	289	28	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	290	1	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	290	2	showed	show	VBD
work_dbbvwgi6and2fokqess5tojy2u	290	3	how	how	WRB
work_dbbvwgi6and2fokqess5tojy2u	290	4	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	290	5	results	result	NNS
work_dbbvwgi6and2fokqess5tojy2u	290	6	can	can	MD
work_dbbvwgi6and2fokqess5tojy2u	290	7	be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	290	8	extrapolated	extrapolate	VBN
work_dbbvwgi6and2fokqess5tojy2u	290	9	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	290	10	other	other	JJ
work_dbbvwgi6and2fokqess5tojy2u	290	11	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	290	12	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	290	13	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	290	14	interference	interference	NN
work_dbbvwgi6and2fokqess5tojy2u	290	15	RNA	RNA	NNP
work_dbbvwgi6and2fokqess5tojy2u	290	16	experiments	experiment	NNS
work_dbbvwgi6and2fokqess5tojy2u	290	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	291	1	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	291	2	knockdown	knockdown	NNP
work_dbbvwgi6and2fokqess5tojy2u	291	3	caused	cause	VBD
work_dbbvwgi6and2fokqess5tojy2u	291	4	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	291	5	increase	increase	NN
work_dbbvwgi6and2fokqess5tojy2u	291	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	291	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	291	8	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	291	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	291	10	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	291	11	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	291	12	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	291	13	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	291	14	decrease	decrease	NN
work_dbbvwgi6and2fokqess5tojy2u	291	15	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	291	16	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	291	17	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	291	18	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	291	19	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	291	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	292	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	292	2	conclusion	conclusion	NN
work_dbbvwgi6and2fokqess5tojy2u	292	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	292	4	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	292	5	show	show	VBP
work_dbbvwgi6and2fokqess5tojy2u	292	6	how	how	WRB
work_dbbvwgi6and2fokqess5tojy2u	292	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	292	8	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	292	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	292	10	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	292	11	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	292	12	correlates	correlate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	292	13	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	292	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	292	15	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	292	16	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	292	17	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	292	18	activities	activity	NNS
work_dbbvwgi6and2fokqess5tojy2u	292	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	292	20	confirming	confirm	VBG
work_dbbvwgi6and2fokqess5tojy2u	292	21	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	292	22	involvement	involvement	NN
work_dbbvwgi6and2fokqess5tojy2u	292	23	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	292	24	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	292	25	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	292	26	cellular	cellular	JJ
work_dbbvwgi6and2fokqess5tojy2u	292	27	processes	process	NNS
work_dbbvwgi6and2fokqess5tojy2u	292	28	regulated	regulate	VBN
work_dbbvwgi6and2fokqess5tojy2u	292	29	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	292	30	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	292	31	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	292	32	25	25	CD
work_dbbvwgi6and2fokqess5tojy2u	292	33	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	292	34	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	292	35	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	292	36	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	292	37	32	32	CD
work_dbbvwgi6and2fokqess5tojy2u	292	38	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	292	39	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	293	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	293	2	tumor	tumor	NN
work_dbbvwgi6and2fokqess5tojy2u	293	3	suppressor	suppressor	NN
work_dbbvwgi6and2fokqess5tojy2u	293	4	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	293	5	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	293	6	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	293	7	mutated	mutate	VBN
work_dbbvwgi6and2fokqess5tojy2u	293	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	293	9	approximately	approximately	RB
work_dbbvwgi6and2fokqess5tojy2u	293	10	50	50	CD
work_dbbvwgi6and2fokqess5tojy2u	293	11	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	293	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	293	13	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	293	14	sporadic	sporadic	JJ
work_dbbvwgi6and2fokqess5tojy2u	293	15	cancers	cancer	NNS
work_dbbvwgi6and2fokqess5tojy2u	293	16	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	293	17	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	293	18	inherited	inherit	VBN
work_dbbvwgi6and2fokqess5tojy2u	293	19	cancer	cancer	NN
work_dbbvwgi6and2fokqess5tojy2u	293	20	predispositions	predisposition	NNS
work_dbbvwgi6and2fokqess5tojy2u	293	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	293	22	such	such	JJ
work_dbbvwgi6and2fokqess5tojy2u	293	23	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	293	24	Li	Li	NNP
work_dbbvwgi6and2fokqess5tojy2u	293	25	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	293	26	Fraumeni	Fraumeni	NNP
work_dbbvwgi6and2fokqess5tojy2u	293	27	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	293	28	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	293	29	27	27	CD
work_dbbvwgi6and2fokqess5tojy2u	293	30	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	293	31	28	28	CD
work_dbbvwgi6and2fokqess5tojy2u	293	32	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	293	33	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	294	1	Homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	294	2	p53-/-	p53-/-	NNP
work_dbbvwgi6and2fokqess5tojy2u	294	3	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	294	4	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	294	5	highly	highly	RB
work_dbbvwgi6and2fokqess5tojy2u	294	6	prone	prone	JJ
work_dbbvwgi6and2fokqess5tojy2u	294	7	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	294	8	cancer	cancer	NN
work_dbbvwgi6and2fokqess5tojy2u	294	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	294	10	particularly	particularly	RB
work_dbbvwgi6and2fokqess5tojy2u	294	11	T	t	NN
work_dbbvwgi6and2fokqess5tojy2u	294	12	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	294	13	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	294	14	lymphoma	lymphoma	NN
work_dbbvwgi6and2fokqess5tojy2u	294	15	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	294	16	sarcoma	sarcoma	NN
work_dbbvwgi6and2fokqess5tojy2u	294	17	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	294	18	36	36	CD
work_dbbvwgi6and2fokqess5tojy2u	294	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	294	20	37	37	CD
work_dbbvwgi6and2fokqess5tojy2u	294	21	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	294	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	295	1	Experiments	experiment	NNS
work_dbbvwgi6and2fokqess5tojy2u	295	2	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	295	3	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	295	4	p53+/-	p53+/-	JJ
work_dbbvwgi6and2fokqess5tojy2u	295	5	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	295	6	indicate	indicate	VBP
work_dbbvwgi6and2fokqess5tojy2u	295	7	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	295	8	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	295	9	mere	mere	JJ
work_dbbvwgi6and2fokqess5tojy2u	295	10	reduction	reduction	NN
work_dbbvwgi6and2fokqess5tojy2u	295	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	295	12	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	295	13	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	295	14	may	may	MD
work_dbbvwgi6and2fokqess5tojy2u	295	15	be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	295	16	sufficient	sufficient	JJ
work_dbbvwgi6and2fokqess5tojy2u	295	17	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	295	18	promote	promote	VB
work_dbbvwgi6and2fokqess5tojy2u	295	19	tumorigenesis	tumorigenesis	NN
work_dbbvwgi6and2fokqess5tojy2u	295	20	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	295	21	38	38	CD
work_dbbvwgi6and2fokqess5tojy2u	295	22	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	295	23	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	296	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	296	2	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	296	3	transcriptional	transcriptional	JJ
work_dbbvwgi6and2fokqess5tojy2u	296	4	activation	activation	NN
work_dbbvwgi6and2fokqess5tojy2u	296	5	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	296	6	dependent	dependent	JJ
work_dbbvwgi6and2fokqess5tojy2u	296	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	296	8	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	296	9	oligomerization	oligomerization	NN
work_dbbvwgi6and2fokqess5tojy2u	296	10	state	state	NN
work_dbbvwgi6and2fokqess5tojy2u	296	11	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	296	12	29	29	CD
work_dbbvwgi6and2fokqess5tojy2u	296	13	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	296	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	296	15	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	296	16	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	296	17	mutations	mutation	NNS
work_dbbvwgi6and2fokqess5tojy2u	296	18	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	296	19	impair	impair	VBP
work_dbbvwgi6and2fokqess5tojy2u	296	20	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	296	21	oligomerization	oligomerization	NN
work_dbbvwgi6and2fokqess5tojy2u	296	22	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	296	23	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	296	24	associated	associate	VBN
work_dbbvwgi6and2fokqess5tojy2u	296	25	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	296	26	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	296	27	Li-	Li-	NNP
work_dbbvwgi6and2fokqess5tojy2u	296	28	Fraumeni	Fraumeni	NNP
work_dbbvwgi6and2fokqess5tojy2u	296	29	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	296	30	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	296	31	30	30	CD
work_dbbvwgi6and2fokqess5tojy2u	296	32	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	296	33	31	31	CD
work_dbbvwgi6and2fokqess5tojy2u	296	34	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	296	35	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	297	1	Because	because	IN
work_dbbvwgi6and2fokqess5tojy2u	297	2	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	297	3	interacts	interact	VBZ
work_dbbvwgi6and2fokqess5tojy2u	297	4	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	297	5	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	297	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	297	7	modulates	modulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	297	8	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	297	9	transcriptional	transcriptional	JJ
work_dbbvwgi6and2fokqess5tojy2u	297	10	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	297	11	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	297	12	regulating	regulate	VBG
work_dbbvwgi6and2fokqess5tojy2u	297	13	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	297	14	oligomerization	oligomerization	NN
work_dbbvwgi6and2fokqess5tojy2u	297	15	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	297	16	32	32	CD
work_dbbvwgi6and2fokqess5tojy2u	297	17	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	297	18	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	297	19	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	297	20	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	297	21	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	297	22	less	less	JJR
work_dbbvwgi6and2fokqess5tojy2u	297	23	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	297	24	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	297	25	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	297	26	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	297	27	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	297	28	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	297	29	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	297	30	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	297	31	would	would	MD
work_dbbvwgi6and2fokqess5tojy2u	297	32	expect	expect	VB
work_dbbvwgi6and2fokqess5tojy2u	297	33	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	297	34	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	297	35	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	297	36	show	show	VB
work_dbbvwgi6and2fokqess5tojy2u	297	37	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	297	38	increased	increase	VBN
work_dbbvwgi6and2fokqess5tojy2u	297	39	susceptibility	susceptibility	NN
work_dbbvwgi6and2fokqess5tojy2u	297	40	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	297	41	developing	develop	VBG
work_dbbvwgi6and2fokqess5tojy2u	297	42	spontaneous	spontaneous	JJ
work_dbbvwgi6and2fokqess5tojy2u	297	43	tumors	tumor	NNS
work_dbbvwgi6and2fokqess5tojy2u	297	44	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	298	1	However	however	RB
work_dbbvwgi6and2fokqess5tojy2u	298	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	298	3	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	298	4	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	298	5	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	298	6	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	298	7	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	298	8	greater	great	JJR
work_dbbvwgi6and2fokqess5tojy2u	298	9	number	number	NN
work_dbbvwgi6and2fokqess5tojy2u	298	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	298	11	tumors	tumor	NNS
work_dbbvwgi6and2fokqess5tojy2u	298	12	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	298	13	Herc2530	herc2530	CD
work_dbbvwgi6and2fokqess5tojy2u	298	14	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	298	15	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	298	16	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	298	17	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	298	18	shown	show	VBN
work_dbbvwgi6and2fokqess5tojy2u	298	19	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	298	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	299	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	299	2	agreement	agreement	NN
work_dbbvwgi6and2fokqess5tojy2u	299	3	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	299	4	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	299	5	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	299	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	299	7	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	299	8	increased	increase	VBN
work_dbbvwgi6and2fokqess5tojy2u	299	9	susceptibility	susceptibility	NN
work_dbbvwgi6and2fokqess5tojy2u	299	10	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	299	11	develop	develop	VB
work_dbbvwgi6and2fokqess5tojy2u	299	12	spontaneous	spontaneous	JJ
work_dbbvwgi6and2fokqess5tojy2u	299	13	tumors	tumor	NNS
work_dbbvwgi6and2fokqess5tojy2u	299	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	299	15	individuals	individual	NNS
work_dbbvwgi6and2fokqess5tojy2u	299	16	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	299	17	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	299	18	Amish	amish	JJ
work_dbbvwgi6and2fokqess5tojy2u	299	19	community	community	NN
work_dbbvwgi6and2fokqess5tojy2u	299	20	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	299	21	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	299	22	HERC2P594L	HERC2P594L	NNP
work_dbbvwgi6and2fokqess5tojy2u	299	23	punctual	punctual	NNP
work_dbbvwgi6and2fokqess5tojy2u	299	24	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	299	25	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	299	26	4,5	4,5	CD
work_dbbvwgi6and2fokqess5tojy2u	299	27	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	299	28	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	299	29	lower	low	JJR
work_dbbvwgi6and2fokqess5tojy2u	299	30	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	299	31	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	299	32	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	299	33	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	299	34	6	6	CD
work_dbbvwgi6and2fokqess5tojy2u	299	35	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	299	36	has	have	VBZ
work_dbbvwgi6and2fokqess5tojy2u	299	37	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	299	38	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	299	39	reported	report	VBN
work_dbbvwgi6and2fokqess5tojy2u	299	40	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	300	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	300	2	hypothesis	hypothesis	NN
work_dbbvwgi6and2fokqess5tojy2u	300	3	that	that	DT
work_dbbvwgi6and2fokqess5tojy2u	300	4	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	300	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	300	6	transcription	transcription	NN
work_dbbvwgi6and2fokqess5tojy2u	300	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	300	8	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	300	9	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	300	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	300	11	driving	drive	VBG
work_dbbvwgi6and2fokqess5tojy2u	300	12	force	force	NN
work_dbbvwgi6and2fokqess5tojy2u	300	13	selected	select	VBN
work_dbbvwgi6and2fokqess5tojy2u	300	14	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	300	15	tumorigenesis	tumorigenesis	NN
work_dbbvwgi6and2fokqess5tojy2u	300	16	needs	need	VBZ
work_dbbvwgi6and2fokqess5tojy2u	300	17	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	300	18	be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	300	19	reevaluated	reevaluate	VBN
work_dbbvwgi6and2fokqess5tojy2u	300	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	300	21	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	300	22	it	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	300	23	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	300	24	far	far	RB
work_dbbvwgi6and2fokqess5tojy2u	300	25	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	300	26	straightforward	straightforward	JJ
work_dbbvwgi6and2fokqess5tojy2u	300	27	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	301	1	For	for	IN
work_dbbvwgi6and2fokqess5tojy2u	301	2	example	example	NN
work_dbbvwgi6and2fokqess5tojy2u	301	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	301	4	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	301	5	expressing	express	VBG
work_dbbvwgi6and2fokqess5tojy2u	301	6	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	301	7	mutants	mutant	NNS
work_dbbvwgi6and2fokqess5tojy2u	301	8	transcriptionally	transcriptionally	RB
work_dbbvwgi6and2fokqess5tojy2u	301	9	defective	defective	JJ
work_dbbvwgi6and2fokqess5tojy2u	301	10	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	301	11	growth	growth	NN
work_dbbvwgi6and2fokqess5tojy2u	301	12	arrest	arrest	NN
work_dbbvwgi6and2fokqess5tojy2u	301	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	301	14	senescence	senescence	NN
work_dbbvwgi6and2fokqess5tojy2u	301	15	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	301	16	apoptosis	apoptosis	NN
work_dbbvwgi6and2fokqess5tojy2u	301	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	301	18	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	301	19	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	301	20	prone	prone	JJ
work_dbbvwgi6and2fokqess5tojy2u	301	21	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	301	22	cancer	cancer	NN
work_dbbvwgi6and2fokqess5tojy2u	301	23	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	301	24	39,40	39,40	CD
work_dbbvwgi6and2fokqess5tojy2u	301	25	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	301	26	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	302	1	Moreover	moreover	RB
work_dbbvwgi6and2fokqess5tojy2u	302	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	302	3	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	302	4	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	302	5	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	302	6	deficient	deficient	JJ
work_dbbvwgi6and2fokqess5tojy2u	302	7	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	302	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	302	9	three	three	CD
work_dbbvwgi6and2fokqess5tojy2u	302	10	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	302	11	target	target	NN
work_dbbvwgi6and2fokqess5tojy2u	302	12	genes	gene	NNS
work_dbbvwgi6and2fokqess5tojy2u	302	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	302	14	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	302	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	302	16	Puma	Puma	NNP
work_dbbvwgi6and2fokqess5tojy2u	302	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	302	18	Noxa	Noxa	NNP
work_dbbvwgi6and2fokqess5tojy2u	302	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	302	20	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	302	21	deficient	deficient	JJ
work_dbbvwgi6and2fokqess5tojy2u	302	22	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	302	23	their	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	302	24	ability	ability	NN
work_dbbvwgi6and2fokqess5tojy2u	302	25	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	302	26	undergo	undergo	VB
work_dbbvwgi6and2fokqess5tojy2u	302	27	p53-mediated	p53-mediated	JJ
work_dbbvwgi6and2fokqess5tojy2u	302	28	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	302	29	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	302	30	cycle	cycle	NN
work_dbbvwgi6and2fokqess5tojy2u	302	31	arrest	arrest	NN
work_dbbvwgi6and2fokqess5tojy2u	302	32	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	302	33	apoptosis	apoptosis	NN
work_dbbvwgi6and2fokqess5tojy2u	302	34	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	302	35	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	302	36	senescence	senescence	NN
work_dbbvwgi6and2fokqess5tojy2u	302	37	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	302	38	although	although	IN
work_dbbvwgi6and2fokqess5tojy2u	302	39	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	302	40	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	302	41	remain	remain	VBP
work_dbbvwgi6and2fokqess5tojy2u	302	42	tumor	tumor	NN
work_dbbvwgi6and2fokqess5tojy2u	302	43	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	302	44	free	free	JJ
work_dbbvwgi6and2fokqess5tojy2u	302	45	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	302	46	41	41	CD
work_dbbvwgi6and2fokqess5tojy2u	302	47	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	302	48	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	303	1	Our	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	303	2	study	study	NN
work_dbbvwgi6and2fokqess5tojy2u	303	3	identifies	identify	VBZ
work_dbbvwgi6and2fokqess5tojy2u	303	4	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	303	5	new	new	JJ
work_dbbvwgi6and2fokqess5tojy2u	303	6	function	function	NN
work_dbbvwgi6and2fokqess5tojy2u	303	7	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	303	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	303	9	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	303	10	ubiquitin	ubiquitin	NNP
work_dbbvwgi6and2fokqess5tojy2u	303	11	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	303	12	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	303	13	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	303	14	regulator	regulator	NN
work_dbbvwgi6and2fokqess5tojy2u	303	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	303	16	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	303	17	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	303	18	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	303	19	regulation	regulation	NN
work_dbbvwgi6and2fokqess5tojy2u	303	20	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	303	21	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	303	22	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	303	23	homeostasis	homeostasis	NN
work_dbbvwgi6and2fokqess5tojy2u	303	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	304	1	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	304	2	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	304	3	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	304	4	expressed	express	VBN
work_dbbvwgi6and2fokqess5tojy2u	304	5	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	304	6	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	304	7	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	304	8	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	304	9	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	304	10	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	304	11	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	304	12	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	305	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	305	2	decrease	decrease	NN
work_dbbvwgi6and2fokqess5tojy2u	305	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	305	4	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	305	5	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	305	6	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	305	7	correlates	correlate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	305	8	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	305	9	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	305	10	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	305	11	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	305	12	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	305	13	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	305	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	305	15	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	305	16	vermis	vermi	NNS
work_dbbvwgi6and2fokqess5tojy2u	305	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	305	18	hemispheres	hemisphere	NNS
work_dbbvwgi6and2fokqess5tojy2u	305	19	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	305	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	305	21	cerebellum	cerebellum	NN
work_dbbvwgi6and2fokqess5tojy2u	305	22	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	305	23	would	would	MD
work_dbbvwgi6and2fokqess5tojy2u	305	24	explain	explain	VB
work_dbbvwgi6and2fokqess5tojy2u	305	25	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	305	26	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	305	27	incoordination	incoordination	NN
work_dbbvwgi6and2fokqess5tojy2u	305	28	detected	detect	VBD
work_dbbvwgi6and2fokqess5tojy2u	305	29	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	305	30	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	305	31	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	305	32	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	305	33	rotarod	rotarod	NN
work_dbbvwgi6and2fokqess5tojy2u	305	34	experiments	experiment	NNS
work_dbbvwgi6and2fokqess5tojy2u	305	35	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	305	36	Figures	figure	NNS
work_dbbvwgi6and2fokqess5tojy2u	305	37	7	7	CD
work_dbbvwgi6and2fokqess5tojy2u	305	38	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	305	39	8)	8)	CD
work_dbbvwgi6and2fokqess5tojy2u	305	40	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	306	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	306	2	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	306	3	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	306	4	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	306	5	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	306	6	bilateral	bilateral	JJ
work_dbbvwgi6and2fokqess5tojy2u	306	7	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	306	8	symmetrical	symmetrical	JJ
work_dbbvwgi6and2fokqess5tojy2u	306	9	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	306	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	306	11	other	other	JJ
work_dbbvwgi6and2fokqess5tojy2u	306	12	mutations	mutation	NNS
work_dbbvwgi6and2fokqess5tojy2u	306	13	characterized	characterize	VBN
work_dbbvwgi6and2fokqess5tojy2u	306	14	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	306	15	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	306	16	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	306	17	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	306	18	loss	loss	VBP
work_dbbvwgi6and2fokqess5tojy2u	306	19	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	306	20	42	42	CD
work_dbbvwgi6and2fokqess5tojy2u	306	21	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	306	22	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	306	23	demonstrating	demonstrate	VBG
work_dbbvwgi6and2fokqess5tojy2u	306	24	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	306	25	specificity	specificity	NN
work_dbbvwgi6and2fokqess5tojy2u	306	26	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	306	27	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	306	28	degenerative	degenerative	JJ
work_dbbvwgi6and2fokqess5tojy2u	306	29	process	process	NN
work_dbbvwgi6and2fokqess5tojy2u	306	30	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	307	1	This	this	DT
work_dbbvwgi6and2fokqess5tojy2u	307	2	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	307	3	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	307	4	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	307	5	homogeneously	homogeneously	RB
work_dbbvwgi6and2fokqess5tojy2u	307	6	distributed	distribute	VBN
work_dbbvwgi6and2fokqess5tojy2u	307	7	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	307	8	thus	thus	RB
work_dbbvwgi6and2fokqess5tojy2u	307	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	307	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	307	11	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	307	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	307	13	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	307	14	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	307	15	appears	appear	VBZ
work_dbbvwgi6and2fokqess5tojy2u	307	16	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	307	17	discrete	discrete	JJ
work_dbbvwgi6and2fokqess5tojy2u	307	18	gaps	gap	NNS
work_dbbvwgi6and2fokqess5tojy2u	307	19	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	307	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	307	21	continuous	continuous	JJ
work_dbbvwgi6and2fokqess5tojy2u	307	22	staining	staining	NN
work_dbbvwgi6and2fokqess5tojy2u	307	23	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	307	24	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	307	25	molecular	molecular	JJ
work_dbbvwgi6and2fokqess5tojy2u	307	26	layer	layer	NN
work_dbbvwgi6and2fokqess5tojy2u	307	27	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	307	28	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	307	29	vermis	vermi	NNS
work_dbbvwgi6and2fokqess5tojy2u	307	30	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	307	31	while	while	IN
work_dbbvwgi6and2fokqess5tojy2u	307	32	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	307	33	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	307	34	hemispheres	hemisphere	NNS
work_dbbvwgi6and2fokqess5tojy2u	307	35	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	307	36	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	307	37	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	307	38	reaches	reach	VBZ
work_dbbvwgi6and2fokqess5tojy2u	307	39	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	307	40	great	great	JJ
work_dbbvwgi6and2fokqess5tojy2u	307	41	extension	extension	NN
work_dbbvwgi6and2fokqess5tojy2u	307	42	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	307	43	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	307	44	8)	8)	CD
work_dbbvwgi6and2fokqess5tojy2u	307	45	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	308	1	Despite	despite	IN
work_dbbvwgi6and2fokqess5tojy2u	308	2	their	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	308	3	homogenous	homogenous	JJ
work_dbbvwgi6and2fokqess5tojy2u	308	4	shapes	shape	NNS
work_dbbvwgi6and2fokqess5tojy2u	308	5	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	308	6	common	common	JJ
work_dbbvwgi6and2fokqess5tojy2u	308	7	morphological	morphological	JJ
work_dbbvwgi6and2fokqess5tojy2u	308	8	features	feature	NNS
work_dbbvwgi6and2fokqess5tojy2u	308	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	308	10	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	308	11	results	result	NNS
work_dbbvwgi6and2fokqess5tojy2u	308	12	suggest	suggest	VBP
work_dbbvwgi6and2fokqess5tojy2u	308	13	some	some	DT
work_dbbvwgi6and2fokqess5tojy2u	308	14	difference	difference	NN
work_dbbvwgi6and2fokqess5tojy2u	308	15	between	between	IN
work_dbbvwgi6and2fokqess5tojy2u	308	16	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	308	17	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	308	18	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	308	19	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	308	20	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	308	21	agreement	agreement	NN
work_dbbvwgi6and2fokqess5tojy2u	308	22	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	308	23	previous	previous	JJ
work_dbbvwgi6and2fokqess5tojy2u	308	24	observations	observation	NNS
work_dbbvwgi6and2fokqess5tojy2u	308	25	indicating	indicate	VBG
work_dbbvwgi6and2fokqess5tojy2u	308	26	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	308	27	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	308	28	neurons	neuron	NNS
work_dbbvwgi6and2fokqess5tojy2u	308	29	do	do	VBP
work_dbbvwgi6and2fokqess5tojy2u	308	30	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	308	31	constitute	constitute	VB
work_dbbvwgi6and2fokqess5tojy2u	308	32	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	308	33	biochemically	biochemically	RB
work_dbbvwgi6and2fokqess5tojy2u	308	34	homogenous	homogenous	JJ
work_dbbvwgi6and2fokqess5tojy2u	308	35	population	population	NN
work_dbbvwgi6and2fokqess5tojy2u	308	36	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	308	37	42,43	42,43	CD
work_dbbvwgi6and2fokqess5tojy2u	308	38	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	308	39	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	309	1	Pathological	pathological	JJ
work_dbbvwgi6and2fokqess5tojy2u	309	2	signs	sign	NNS
work_dbbvwgi6and2fokqess5tojy2u	309	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	309	4	such	such	JJ
work_dbbvwgi6and2fokqess5tojy2u	309	5	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	309	6	varicose	varicose	JJ
work_dbbvwgi6and2fokqess5tojy2u	309	7	enlargements	enlargement	NNS
work_dbbvwgi6and2fokqess5tojy2u	309	8	resembling	resemble	VBG
work_dbbvwgi6and2fokqess5tojy2u	309	9	axonal	axonal	JJ
work_dbbvwgi6and2fokqess5tojy2u	309	10	torpedoes	torpedo	NNS
work_dbbvwgi6and2fokqess5tojy2u	309	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	309	12	widespread	widespread	JJ
work_dbbvwgi6and2fokqess5tojy2u	309	13	accumulations	accumulation	NNS
work_dbbvwgi6and2fokqess5tojy2u	309	14	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	309	15	dense	dense	JJ
work_dbbvwgi6and2fokqess5tojy2u	309	16	cytoplasmic	cytoplasmic	JJ
work_dbbvwgi6and2fokqess5tojy2u	309	17	material	material	NN
work_dbbvwgi6and2fokqess5tojy2u	309	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	309	19	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	309	20	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	309	21	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	309	22	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	309	23	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	309	24	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	309	25	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	309	26	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	309	27	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	310	1	Proliferation	Proliferation	NNP
work_dbbvwgi6and2fokqess5tojy2u	310	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	310	3	Golgi	Golgi	NNP
work_dbbvwgi6and2fokqess5tojy2u	310	4	epithelial	epithelial	JJ
work_dbbvwgi6and2fokqess5tojy2u	310	5	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	310	6	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	310	7	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	310	8	indicative	indicative	JJ
work_dbbvwgi6and2fokqess5tojy2u	310	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	310	10	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	310	11	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	310	12	degeneration	degeneration	NN
work_dbbvwgi6and2fokqess5tojy2u	310	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	311	1	Electron	Electron	NNP
work_dbbvwgi6and2fokqess5tojy2u	311	2	microscopy	microscopy	JJ
work_dbbvwgi6and2fokqess5tojy2u	311	3	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	311	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	311	5	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	311	6	cerebella	cerebella	NN
work_dbbvwgi6and2fokqess5tojy2u	311	7	showed	show	VBD
work_dbbvwgi6and2fokqess5tojy2u	311	8	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	311	9	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	311	10	containing	contain	VBG
work_dbbvwgi6and2fokqess5tojy2u	311	11	numerous	numerous	JJ
work_dbbvwgi6and2fokqess5tojy2u	311	12	degenerating	degenerating	NN
work_dbbvwgi6and2fokqess5tojy2u	311	13	signs	sign	NNS
work_dbbvwgi6and2fokqess5tojy2u	311	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	311	15	autophagosomes	autophagosome	NNS
work_dbbvwgi6and2fokqess5tojy2u	311	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	311	17	lysosomes	lysosomes	NNP
work_dbbvwgi6and2fokqess5tojy2u	311	18	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	311	19	Golgi	Golgi	NNP
work_dbbvwgi6and2fokqess5tojy2u	311	20	cisterns	cistern	NNS
work_dbbvwgi6and2fokqess5tojy2u	311	21	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	311	22	Figure	figure	NN
work_dbbvwgi6and2fokqess5tojy2u	311	23	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	311	24	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	311	25	11	11	CD
work_dbbvwgi6and2fokqess5tojy2u	311	26	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	311	27	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	311	28	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	311	29	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	311	30	shown	show	VBN
work_dbbvwgi6and2fokqess5tojy2u	311	31	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	311	32	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	312	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	312	2	results	result	NNS
work_dbbvwgi6and2fokqess5tojy2u	312	3	resemble	resemble	VBP
work_dbbvwgi6and2fokqess5tojy2u	312	4	those	those	DT
work_dbbvwgi6and2fokqess5tojy2u	312	5	obtained	obtain	VBN
work_dbbvwgi6and2fokqess5tojy2u	312	6	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	312	7	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	312	8	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	312	9	mutant	mutant	JJ
work_dbbvwgi6and2fokqess5tojy2u	312	10	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	312	11	called	call	VBN
work_dbbvwgi6and2fokqess5tojy2u	312	12	tambaleante	tambaleante	NNP
work_dbbvwgi6and2fokqess5tojy2u	312	13	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	312	14	44,45	44,45	CD
work_dbbvwgi6and2fokqess5tojy2u	312	15	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	312	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	313	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	313	2	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	313	3	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	313	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	313	5	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	313	6	progressive	progressive	JJ
work_dbbvwgi6and2fokqess5tojy2u	313	7	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	313	8	specific	specific	JJ
work_dbbvwgi6and2fokqess5tojy2u	313	9	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	313	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	313	11	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	313	12	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	313	13	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	313	14	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	313	15	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	313	16	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	313	17	very	very	RB
work_dbbvwgi6and2fokqess5tojy2u	313	18	similar	similar	JJ
work_dbbvwgi6and2fokqess5tojy2u	313	19	pattern	pattern	NN
work_dbbvwgi6and2fokqess5tojy2u	313	20	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	313	21	neurodegenerative	neurodegenerative	JJ
work_dbbvwgi6and2fokqess5tojy2u	313	22	signs	sign	NNS
work_dbbvwgi6and2fokqess5tojy2u	313	23	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	314	1	Interestingly	interestingly	RB
work_dbbvwgi6and2fokqess5tojy2u	314	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	314	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	314	4	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	314	5	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	314	6	degeneration	degeneration	NN
work_dbbvwgi6and2fokqess5tojy2u	314	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	314	8	tambaleante	tambaleante	JJ
work_dbbvwgi6and2fokqess5tojy2u	314	9	mutant	mutant	JJ
work_dbbvwgi6and2fokqess5tojy2u	314	10	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	314	11	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	314	12	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	314	13	consequence	consequence	NN
work_dbbvwgi6and2fokqess5tojy2u	314	14	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	314	15	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	314	16	missense	missense	NN
work_dbbvwgi6and2fokqess5tojy2u	314	17	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	314	18	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	314	19	HERC1	HERC1	NNP
work_dbbvwgi6and2fokqess5tojy2u	314	20	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	314	21	44	44	CD
work_dbbvwgi6and2fokqess5tojy2u	314	22	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	314	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	314	24	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	314	25	structural	structural	JJ
work_dbbvwgi6and2fokqess5tojy2u	314	26	homolog	homolog	NN
work_dbbvwgi6and2fokqess5tojy2u	314	27	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	314	28	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	314	29	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	315	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	315	2	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	315	3	regard	regard	NN
work_dbbvwgi6and2fokqess5tojy2u	315	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	315	5	it	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	315	6	seems	seem	VBZ
work_dbbvwgi6and2fokqess5tojy2u	315	7	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	315	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	315	9	functional	functional	JJ
work_dbbvwgi6and2fokqess5tojy2u	315	10	alteration	alteration	NN
work_dbbvwgi6and2fokqess5tojy2u	315	11	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	315	12	one	one	CD
work_dbbvwgi6and2fokqess5tojy2u	315	13	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	315	14	them	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	315	15	it	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	315	16	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	315	17	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	315	18	compensated	compensate	VBN
work_dbbvwgi6and2fokqess5tojy2u	315	19	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	315	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	315	21	other	other	JJ
work_dbbvwgi6and2fokqess5tojy2u	315	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	316	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	316	2	agreement	agreement	NN
work_dbbvwgi6and2fokqess5tojy2u	316	3	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	316	4	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	316	5	independent	independent	JJ
work_dbbvwgi6and2fokqess5tojy2u	316	6	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	316	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	316	8	HERC1	herc1	NN
work_dbbvwgi6and2fokqess5tojy2u	316	9	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	316	10	HERC2	herc2	NN
work_dbbvwgi6and2fokqess5tojy2u	316	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	316	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	316	13	essential	essential	JJ
work_dbbvwgi6and2fokqess5tojy2u	316	14	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	316	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	316	16	HERC1	HERC1	NNS
work_dbbvwgi6and2fokqess5tojy2u	316	17	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	316	18	normal	normal	JJ
work_dbbvwgi6and2fokqess5tojy2u	316	19	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	316	20	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	316	21	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	316	22	neurotransmission	neurotransmission	NN
work_dbbvwgi6and2fokqess5tojy2u	316	23	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	316	24	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	316	25	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	316	26	neuromuscular	neuromuscular	NNP
work_dbbvwgi6and2fokqess5tojy2u	316	27	junction	junction	NNP
work_dbbvwgi6and2fokqess5tojy2u	316	28	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	316	29	46	46	CD
work_dbbvwgi6and2fokqess5tojy2u	316	30	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	316	31	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	316	32	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	316	33	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	316	34	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	316	35	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	316	36	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	316	37	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	316	38	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	316	39	7	7	CD
work_dbbvwgi6and2fokqess5tojy2u	316	40	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	316	41	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	317	1	Thus	thus	RB
work_dbbvwgi6and2fokqess5tojy2u	317	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	317	3	both	both	DT
work_dbbvwgi6and2fokqess5tojy2u	317	4	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	317	5	ligases	ligase	NNS
work_dbbvwgi6and2fokqess5tojy2u	317	6	seem	seem	VBP
work_dbbvwgi6and2fokqess5tojy2u	317	7	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	317	8	have	have	VB
work_dbbvwgi6and2fokqess5tojy2u	317	9	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	317	10	crucial	crucial	JJ
work_dbbvwgi6and2fokqess5tojy2u	317	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	317	12	independent	independent	JJ
work_dbbvwgi6and2fokqess5tojy2u	317	13	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	317	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	317	15	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	317	16	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	317	17	physiology	physiology	NN
work_dbbvwgi6and2fokqess5tojy2u	317	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	318	1	This	this	DT
work_dbbvwgi6and2fokqess5tojy2u	318	2	functional	functional	JJ
work_dbbvwgi6and2fokqess5tojy2u	318	3	similarity	similarity	NN
work_dbbvwgi6and2fokqess5tojy2u	318	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	318	5	HERC1	HERC1	NNP
work_dbbvwgi6and2fokqess5tojy2u	318	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	318	7	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	318	8	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	318	9	unexpected	unexpected	JJ
work_dbbvwgi6and2fokqess5tojy2u	318	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	318	11	because	because	IN
work_dbbvwgi6and2fokqess5tojy2u	318	12	despite	despite	IN
work_dbbvwgi6and2fokqess5tojy2u	318	13	their	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	318	14	structural	structural	JJ
work_dbbvwgi6and2fokqess5tojy2u	318	15	homology	homology	NN
work_dbbvwgi6and2fokqess5tojy2u	318	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	318	17	endogenous	endogenous	JJ
work_dbbvwgi6and2fokqess5tojy2u	318	18	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	318	19	do	do	VBP
work_dbbvwgi6and2fokqess5tojy2u	318	20	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	318	21	interact	interact	VB
work_dbbvwgi6and2fokqess5tojy2u	318	22	between	between	IN
work_dbbvwgi6and2fokqess5tojy2u	318	23	them	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	318	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	318	25	do	do	VBP
work_dbbvwgi6and2fokqess5tojy2u	318	26	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	318	27	have	have	VB
work_dbbvwgi6and2fokqess5tojy2u	318	28	common	common	JJ
work_dbbvwgi6and2fokqess5tojy2u	318	29	known	know	VBN
work_dbbvwgi6and2fokqess5tojy2u	318	30	interactors	interactor	NNS
work_dbbvwgi6and2fokqess5tojy2u	318	31	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	318	32	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	318	33	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	318	34	subcellular	subcellular	JJ
work_dbbvwgi6and2fokqess5tojy2u	318	35	locations	location	NNS
work_dbbvwgi6and2fokqess5tojy2u	318	36	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	318	37	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	318	38	involved	involve	VBN
work_dbbvwgi6and2fokqess5tojy2u	318	39	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	318	40	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	318	41	pathways	pathway	NNS
work_dbbvwgi6and2fokqess5tojy2u	318	42	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	318	43	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	318	44	signaling	signal	VBG
work_dbbvwgi6and2fokqess5tojy2u	318	45	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	318	46	11	11	CD
work_dbbvwgi6and2fokqess5tojy2u	318	47	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	318	48	12	12	CD
work_dbbvwgi6and2fokqess5tojy2u	318	49	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	318	50	32	32	CD
work_dbbvwgi6and2fokqess5tojy2u	318	51	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	318	52	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	319	1	However	however	RB
work_dbbvwgi6and2fokqess5tojy2u	319	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	319	3	Oncotarget56100www.impactjournals.com/oncotarget	oncotarget56100www.impactjournals.com/oncotarget	VBP
work_dbbvwgi6and2fokqess5tojy2u	319	4	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	319	5	interaction	interaction	NN
work_dbbvwgi6and2fokqess5tojy2u	319	6	between	between	IN
work_dbbvwgi6and2fokqess5tojy2u	319	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	319	8	first	first	JJ
work_dbbvwgi6and2fokqess5tojy2u	319	9	1,000	1,000	CD
work_dbbvwgi6and2fokqess5tojy2u	319	10	amino	amino	NN
work_dbbvwgi6and2fokqess5tojy2u	319	11	acid	acid	NN
work_dbbvwgi6and2fokqess5tojy2u	319	12	residues	residue	NNS
work_dbbvwgi6and2fokqess5tojy2u	319	13	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	319	14	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	319	15	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	319	16	HERC1	HERC1	NNP
work_dbbvwgi6and2fokqess5tojy2u	319	17	has	have	VBZ
work_dbbvwgi6and2fokqess5tojy2u	319	18	recently	recently	RB
work_dbbvwgi6and2fokqess5tojy2u	319	19	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	319	20	detected	detect	VBN
work_dbbvwgi6and2fokqess5tojy2u	319	21	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	319	22	mass	mass	NN
work_dbbvwgi6and2fokqess5tojy2u	319	23	spectrometry	spectrometry	NN
work_dbbvwgi6and2fokqess5tojy2u	319	24	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	319	25	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	319	26	47	47	CD
work_dbbvwgi6and2fokqess5tojy2u	319	27	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	319	28	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	319	29	suggesting	suggest	VBG
work_dbbvwgi6and2fokqess5tojy2u	319	30	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	319	31	possible	possible	JJ
work_dbbvwgi6and2fokqess5tojy2u	319	32	interaction	interaction	NN
work_dbbvwgi6and2fokqess5tojy2u	319	33	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	319	34	some	some	DT
work_dbbvwgi6and2fokqess5tojy2u	319	35	unknown	unknown	JJ
work_dbbvwgi6and2fokqess5tojy2u	319	36	circumstances	circumstance	NNS
work_dbbvwgi6and2fokqess5tojy2u	319	37	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	320	1	A	a	DT
work_dbbvwgi6and2fokqess5tojy2u	320	2	functional	functional	JJ
work_dbbvwgi6and2fokqess5tojy2u	320	3	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	320	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	320	5	cerebellar	cerebellar	JJ
work_dbbvwgi6and2fokqess5tojy2u	320	6	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	320	7	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	320	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	320	9	adult	adult	NN
work_dbbvwgi6and2fokqess5tojy2u	320	10	walking	walk	VBG
work_dbbvwgi6and2fokqess5tojy2u	320	11	synchronization	synchronization	NN
work_dbbvwgi6and2fokqess5tojy2u	320	12	has	have	VBZ
work_dbbvwgi6and2fokqess5tojy2u	320	13	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	320	14	reported	report	VBN
work_dbbvwgi6and2fokqess5tojy2u	320	15	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	320	16	48	48	CD
work_dbbvwgi6and2fokqess5tojy2u	320	17	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	320	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	321	1	Because	because	IN
work_dbbvwgi6and2fokqess5tojy2u	321	2	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	321	3	positively	positively	RB
work_dbbvwgi6and2fokqess5tojy2u	321	4	regulates	regulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	321	5	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	321	6	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	321	7	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	321	8	32	32	CD
work_dbbvwgi6and2fokqess5tojy2u	321	9	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	321	10	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	321	11	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	321	12	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	321	13	had	have	VBD
work_dbbvwgi6and2fokqess5tojy2u	321	14	less	less	JJR
work_dbbvwgi6and2fokqess5tojy2u	321	15	HERC2	herc2	DT
work_dbbvwgi6and2fokqess5tojy2u	321	16	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	321	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	321	18	it	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	321	19	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	321	20	plausible	plausible	JJ
work_dbbvwgi6and2fokqess5tojy2u	321	21	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	321	22	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	321	23	impaired	impaired	JJ
work_dbbvwgi6and2fokqess5tojy2u	321	24	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	321	25	synchronization	synchronization	NN
work_dbbvwgi6and2fokqess5tojy2u	321	26	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	321	27	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	321	28	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	321	29	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	321	30	caused	cause	VBN
work_dbbvwgi6and2fokqess5tojy2u	321	31	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	321	32	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	321	33	decrease	decrease	NN
work_dbbvwgi6and2fokqess5tojy2u	321	34	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	321	35	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	321	36	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	321	37	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	322	1	For	for	IN
work_dbbvwgi6and2fokqess5tojy2u	322	2	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	322	3	reason	reason	NN
work_dbbvwgi6and2fokqess5tojy2u	322	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	322	5	we	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	322	6	analyzed	analyze	VBD
work_dbbvwgi6and2fokqess5tojy2u	322	7	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	322	8	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	322	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	322	10	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	322	11	knockout	knockout	NN
work_dbbvwgi6and2fokqess5tojy2u	322	12	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	322	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	323	1	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	323	2	did	do	VBD
work_dbbvwgi6and2fokqess5tojy2u	323	3	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	323	4	observe	observe	VB
work_dbbvwgi6and2fokqess5tojy2u	323	5	significant	significant	JJ
work_dbbvwgi6and2fokqess5tojy2u	323	6	differences	difference	NNS
work_dbbvwgi6and2fokqess5tojy2u	323	7	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	323	8	rotarod	rotarod	NN
work_dbbvwgi6and2fokqess5tojy2u	323	9	experiments	experiment	NNS
work_dbbvwgi6and2fokqess5tojy2u	323	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	323	11	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	323	12	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	323	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	323	14	Figure	Figure	NNP
work_dbbvwgi6and2fokqess5tojy2u	323	15	7	7	CD
work_dbbvwgi6and2fokqess5tojy2u	323	16	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	323	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	324	1	Our	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	324	2	results	result	NNS
work_dbbvwgi6and2fokqess5tojy2u	324	3	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	324	4	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	324	5	agreement	agreement	NN
work_dbbvwgi6and2fokqess5tojy2u	324	6	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	324	7	other	other	JJ
work_dbbvwgi6and2fokqess5tojy2u	324	8	studies	study	NNS
work_dbbvwgi6and2fokqess5tojy2u	324	9	where	where	WRB
work_dbbvwgi6and2fokqess5tojy2u	324	10	no	no	DT
work_dbbvwgi6and2fokqess5tojy2u	324	11	differences	difference	NNS
work_dbbvwgi6and2fokqess5tojy2u	324	12	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	324	13	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	324	14	synchronization	synchronization	NN
work_dbbvwgi6and2fokqess5tojy2u	324	15	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	324	16	detected	detect	VBN
work_dbbvwgi6and2fokqess5tojy2u	324	17	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	324	18	Tomasevic	Tomasevic	NNP
work_dbbvwgi6and2fokqess5tojy2u	324	19	et	et	FW
work_dbbvwgi6and2fokqess5tojy2u	324	20	al	al	NNP
work_dbbvwgi6and2fokqess5tojy2u	324	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	325	1	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	325	2	49	49	CD
work_dbbvwgi6and2fokqess5tojy2u	325	3	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	325	4	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	325	5	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	325	6	knockout	knockout	NN
work_dbbvwgi6and2fokqess5tojy2u	325	7	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	325	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	326	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	326	2	authors	author	NNS
work_dbbvwgi6and2fokqess5tojy2u	326	3	described	describe	VBD
work_dbbvwgi6and2fokqess5tojy2u	326	4	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	326	5	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	326	6	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	326	7	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	326	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	326	9	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	326	10	recovery	recovery	NN
work_dbbvwgi6and2fokqess5tojy2u	326	11	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	326	12	neuromotor	neuromotor	NN
work_dbbvwgi6and2fokqess5tojy2u	326	13	function	function	NN
work_dbbvwgi6and2fokqess5tojy2u	326	14	after	after	IN
work_dbbvwgi6and2fokqess5tojy2u	326	15	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	326	16	traumatic	traumatic	JJ
work_dbbvwgi6and2fokqess5tojy2u	326	17	brain	brain	NN
work_dbbvwgi6and2fokqess5tojy2u	326	18	injury	injury	NN
work_dbbvwgi6and2fokqess5tojy2u	326	19	but	but	CC
work_dbbvwgi6and2fokqess5tojy2u	326	20	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	326	21	before	before	IN
work_dbbvwgi6and2fokqess5tojy2u	326	22	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	326	23	injury	injury	NN
work_dbbvwgi6and2fokqess5tojy2u	326	24	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	326	25	49	49	CD
work_dbbvwgi6and2fokqess5tojy2u	326	26	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	326	27	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	327	1	Thus	thus	RB
work_dbbvwgi6and2fokqess5tojy2u	327	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	327	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	327	4	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	327	5	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	327	6	regulated	regulate	VBN
work_dbbvwgi6and2fokqess5tojy2u	327	7	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	327	8	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	327	9	seems	seem	VBZ
work_dbbvwgi6and2fokqess5tojy2u	327	10	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	327	11	be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	327	12	independent	independent	JJ
work_dbbvwgi6and2fokqess5tojy2u	327	13	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	327	14	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	327	15	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	327	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	328	1	Pioneering	pioneer	VBG
work_dbbvwgi6and2fokqess5tojy2u	328	2	studies	study	NNS
work_dbbvwgi6and2fokqess5tojy2u	328	3	associated	associate	VBD
work_dbbvwgi6and2fokqess5tojy2u	328	4	mutations	mutation	NNS
work_dbbvwgi6and2fokqess5tojy2u	328	5	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	328	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	328	7	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	328	8	Herc2	Herc2	NNP
work_dbbvwgi6and2fokqess5tojy2u	328	9	locus	locus	NN
work_dbbvwgi6and2fokqess5tojy2u	328	10	induced	induce	VBN
work_dbbvwgi6and2fokqess5tojy2u	328	11	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	328	12	ethylnitrosourea	ethylnitrosourea	NNP
work_dbbvwgi6and2fokqess5tojy2u	328	13	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	328	14	ionizing	ionize	VBG
work_dbbvwgi6and2fokqess5tojy2u	328	15	radiation	radiation	NN
work_dbbvwgi6and2fokqess5tojy2u	328	16	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	328	17	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	328	18	runty	runty	NN
work_dbbvwgi6and2fokqess5tojy2u	328	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	328	20	jerky	jerky	NNP
work_dbbvwgi6and2fokqess5tojy2u	328	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	328	22	sterile	sterile	JJ
work_dbbvwgi6and2fokqess5tojy2u	328	23	phenotype	phenotype	NN
work_dbbvwgi6and2fokqess5tojy2u	328	24	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	328	25	rjs	rjs	NNP
work_dbbvwgi6and2fokqess5tojy2u	328	26	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	328	27	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	328	28	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	328	29	known	know	VBN
work_dbbvwgi6and2fokqess5tojy2u	328	30	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	328	31	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	328	32	juvenile	juvenile	JJ
work_dbbvwgi6and2fokqess5tojy2u	328	33	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	328	34	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	328	35	fertility	fertility	NN
work_dbbvwgi6and2fokqess5tojy2u	328	36	phenotype	phenotype	NNP
work_dbbvwgi6and2fokqess5tojy2u	328	37	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	328	38	jfd2	jfd2	NNP
work_dbbvwgi6and2fokqess5tojy2u	328	39	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	328	40	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	328	41	characterized	characterize	VBN
work_dbbvwgi6and2fokqess5tojy2u	328	42	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	328	43	reduced	reduce	VBN
work_dbbvwgi6and2fokqess5tojy2u	328	44	size	size	NN
work_dbbvwgi6and2fokqess5tojy2u	328	45	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	328	46	jerky	jerky	NNP
work_dbbvwgi6and2fokqess5tojy2u	328	47	gait	gait	NNP
work_dbbvwgi6and2fokqess5tojy2u	328	48	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	328	49	fertility	fertility	NN
work_dbbvwgi6and2fokqess5tojy2u	328	50	problems	problem	NNS
work_dbbvwgi6and2fokqess5tojy2u	328	51	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	328	52	including	include	VBG
work_dbbvwgi6and2fokqess5tojy2u	328	53	spermatocyte	spermatocyte	JJ
work_dbbvwgi6and2fokqess5tojy2u	328	54	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	328	55	oocyte	oocyte	JJ
work_dbbvwgi6and2fokqess5tojy2u	328	56	abnormalities	abnormality	NNS
work_dbbvwgi6and2fokqess5tojy2u	328	57	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	328	58	defective	defective	JJ
work_dbbvwgi6and2fokqess5tojy2u	328	59	maternal	maternal	JJ
work_dbbvwgi6and2fokqess5tojy2u	328	60	behaviour	behaviour	NN
work_dbbvwgi6and2fokqess5tojy2u	328	61	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	328	62	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	328	63	reduced	reduced	JJ
work_dbbvwgi6and2fokqess5tojy2u	328	64	lifespan	lifespan	NN
work_dbbvwgi6and2fokqess5tojy2u	328	65	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	328	66	juvenile	juvenile	JJ
work_dbbvwgi6and2fokqess5tojy2u	328	67	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	328	68	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	328	69	50	50	CD
work_dbbvwgi6and2fokqess5tojy2u	328	70	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	328	71	52	52	CD
work_dbbvwgi6and2fokqess5tojy2u	328	72	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	328	73	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	329	1	More	more	RBR
work_dbbvwgi6and2fokqess5tojy2u	329	2	recently	recently	RB
work_dbbvwgi6and2fokqess5tojy2u	329	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	329	4	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	329	5	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	329	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	329	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	329	8	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	329	9	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	329	10	has	have	VBZ
work_dbbvwgi6and2fokqess5tojy2u	329	11	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	329	12	linked	link	VBN
work_dbbvwgi6and2fokqess5tojy2u	329	13	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	329	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	329	15	neurodevelopmental	neurodevelopmental	NNP
work_dbbvwgi6and2fokqess5tojy2u	329	16	delay	delay	NN
work_dbbvwgi6and2fokqess5tojy2u	329	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	329	18	dysfunction	dysfunction	NN
work_dbbvwgi6and2fokqess5tojy2u	329	19	seen	see	VBN
work_dbbvwgi6and2fokqess5tojy2u	329	20	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	329	21	Angelman	Angelman	NNP
work_dbbvwgi6and2fokqess5tojy2u	329	22	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	329	23	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	329	24	autism	autism	NN
work_dbbvwgi6and2fokqess5tojy2u	329	25	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	329	26	spectrum	spectrum	NN
work_dbbvwgi6and2fokqess5tojy2u	329	27	disorders	disorder	NNS
work_dbbvwgi6and2fokqess5tojy2u	329	28	among	among	IN
work_dbbvwgi6and2fokqess5tojy2u	329	29	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	329	30	Amish	amish	JJ
work_dbbvwgi6and2fokqess5tojy2u	329	31	community	community	NN
work_dbbvwgi6and2fokqess5tojy2u	329	32	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	329	33	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	329	34	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	329	35	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	329	36	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	329	37	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	330	1	Now	now	RB
work_dbbvwgi6and2fokqess5tojy2u	330	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	330	3	our	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	330	4	study	study	NN
work_dbbvwgi6and2fokqess5tojy2u	330	5	demonstrates	demonstrate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	330	6	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	330	7	important	important	JJ
work_dbbvwgi6and2fokqess5tojy2u	330	8	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	330	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	330	10	HERC2	herc2	NN
work_dbbvwgi6and2fokqess5tojy2u	330	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	330	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	330	13	regulation	regulation	NN
work_dbbvwgi6and2fokqess5tojy2u	330	14	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	330	15	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	330	16	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	330	17	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	330	18	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	330	19	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	330	20	homeostasis	homeostasis	NN
work_dbbvwgi6and2fokqess5tojy2u	330	21	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	330	22	would	would	MD
work_dbbvwgi6and2fokqess5tojy2u	330	23	explain	explain	VB
work_dbbvwgi6and2fokqess5tojy2u	330	24	some	some	DT
work_dbbvwgi6and2fokqess5tojy2u	330	25	features	feature	NNS
work_dbbvwgi6and2fokqess5tojy2u	330	26	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	330	27	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	330	28	rjs	rjs	NNP
work_dbbvwgi6and2fokqess5tojy2u	330	29	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	330	30	jdf2	jdf2	NN
work_dbbvwgi6and2fokqess5tojy2u	330	31	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	330	32	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	330	33	individuals	individual	NNS
work_dbbvwgi6and2fokqess5tojy2u	330	34	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	330	35	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	330	36	HERC2P594L	HERC2P594L	NNP
work_dbbvwgi6and2fokqess5tojy2u	330	37	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	330	38	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	331	1	It	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	331	2	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	331	3	important	important	JJ
work_dbbvwgi6and2fokqess5tojy2u	331	4	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	331	5	note	note	VB
work_dbbvwgi6and2fokqess5tojy2u	331	6	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	331	7	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	331	8	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	331	9	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	331	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	331	11	above	above	JJ
work_dbbvwgi6and2fokqess5tojy2u	331	12	studies	study	NNS
work_dbbvwgi6and2fokqess5tojy2u	331	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	331	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	331	15	impaired	impaired	JJ
work_dbbvwgi6and2fokqess5tojy2u	331	16	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	331	17	synchronization	synchronization	NN
work_dbbvwgi6and2fokqess5tojy2u	331	18	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	331	19	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	331	20	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	331	21	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	331	22	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	331	23	only	only	RB
work_dbbvwgi6and2fokqess5tojy2u	331	24	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	331	25	mutated	mutate	VBN
work_dbbvwgi6and2fokqess5tojy2u	331	26	allele	allele	NN
work_dbbvwgi6and2fokqess5tojy2u	331	27	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	331	28	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	331	29	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	331	30	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	331	31	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	331	32	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	331	33	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	331	34	indicating	indicate	VBG
work_dbbvwgi6and2fokqess5tojy2u	331	35	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	331	36	relevance	relevance	NN
work_dbbvwgi6and2fokqess5tojy2u	331	37	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	331	38	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	331	39	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	331	40	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	331	41	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	331	42	function	function	NN
work_dbbvwgi6and2fokqess5tojy2u	331	43	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	331	44	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	332	1	Studies	study	NNS
work_dbbvwgi6and2fokqess5tojy2u	332	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	332	3	spontaneous	spontaneous	JJ
work_dbbvwgi6and2fokqess5tojy2u	332	4	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	332	5	mutants	mutant	NNS
work_dbbvwgi6and2fokqess5tojy2u	332	6	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	332	7	implicated	implicate	VBN
work_dbbvwgi6and2fokqess5tojy2u	332	8	autophagy	autophagy	NN
work_dbbvwgi6and2fokqess5tojy2u	332	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	332	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	332	11	death	death	NN
work_dbbvwgi6and2fokqess5tojy2u	332	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	332	13	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	332	14	neurons	neuron	NNS
work_dbbvwgi6and2fokqess5tojy2u	332	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	333	1	Lurcher	lurcher	NN
work_dbbvwgi6and2fokqess5tojy2u	333	2	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	333	3	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	333	4	mutations	mutation	NNS
work_dbbvwgi6and2fokqess5tojy2u	333	5	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	333	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	333	7	delta2	delta2	NNP
work_dbbvwgi6and2fokqess5tojy2u	333	8	glutamate	glutamate	NNP
work_dbbvwgi6and2fokqess5tojy2u	333	9	receptor	receptor	NN
work_dbbvwgi6and2fokqess5tojy2u	333	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	333	11	pcd	pcd	NN
work_dbbvwgi6and2fokqess5tojy2u	333	12	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	333	13	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	333	14	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	333	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	333	16	nna1	nna1	NN
work_dbbvwgi6and2fokqess5tojy2u	333	17	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	333	18	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	333	19	tambaleante	tambaleante	JJ
work_dbbvwgi6and2fokqess5tojy2u	333	20	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	333	21	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	333	22	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	333	23	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	333	24	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	333	25	HERC1	herc1	CD
work_dbbvwgi6and2fokqess5tojy2u	333	26	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	333	27	show	show	VBP
work_dbbvwgi6and2fokqess5tojy2u	333	28	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	333	29	increase	increase	NN
work_dbbvwgi6and2fokqess5tojy2u	333	30	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	333	31	autophagy	autophagy	NNS
work_dbbvwgi6and2fokqess5tojy2u	333	32	associated	associate	VBN
work_dbbvwgi6and2fokqess5tojy2u	333	33	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	333	34	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	333	35	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	333	36	death	death	NN
work_dbbvwgi6and2fokqess5tojy2u	333	37	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	333	38	44	44	CD
work_dbbvwgi6and2fokqess5tojy2u	333	39	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	333	40	53	53	CD
work_dbbvwgi6and2fokqess5tojy2u	333	41	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	333	42	55	55	CD
work_dbbvwgi6and2fokqess5tojy2u	333	43	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	333	44	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	334	1	While	while	IN
work_dbbvwgi6and2fokqess5tojy2u	334	2	conditional	conditional	JJ
work_dbbvwgi6and2fokqess5tojy2u	334	3	inactivation	inactivation	NN
work_dbbvwgi6and2fokqess5tojy2u	334	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	334	5	autophagy	autophagy	NN
work_dbbvwgi6and2fokqess5tojy2u	334	6	genes	gene	NNS
work_dbbvwgi6and2fokqess5tojy2u	334	7	such	such	JJ
work_dbbvwgi6and2fokqess5tojy2u	334	8	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	334	9	Atg5	Atg5	NNP
work_dbbvwgi6and2fokqess5tojy2u	334	10	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	334	11	Atg7	Atg7	NNP
work_dbbvwgi6and2fokqess5tojy2u	334	12	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	334	13	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	334	14	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	334	15	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	334	16	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	334	17	yields	yield	NNS
work_dbbvwgi6and2fokqess5tojy2u	334	18	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	334	19	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	334	20	degeneration	degeneration	NN
work_dbbvwgi6and2fokqess5tojy2u	334	21	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	334	22	death	death	NN
work_dbbvwgi6and2fokqess5tojy2u	334	23	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	334	24	56	56	CD
work_dbbvwgi6and2fokqess5tojy2u	334	25	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	334	26	57	57	CD
work_dbbvwgi6and2fokqess5tojy2u	334	27	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	334	28	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	335	1	This	this	DT
work_dbbvwgi6and2fokqess5tojy2u	335	2	dual	dual	JJ
work_dbbvwgi6and2fokqess5tojy2u	335	3	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	335	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	335	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	335	6	autophagy	autophagy	NN
work_dbbvwgi6and2fokqess5tojy2u	335	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	335	8	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	335	9	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	335	10	degeneration	degeneration	NN
work_dbbvwgi6and2fokqess5tojy2u	335	11	seems	seem	VBZ
work_dbbvwgi6and2fokqess5tojy2u	335	12	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	335	13	indicate	indicate	VB
work_dbbvwgi6and2fokqess5tojy2u	335	14	that	that	IN
work_dbbvwgi6and2fokqess5tojy2u	335	15	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	335	16	neurons	neuron	NNS
work_dbbvwgi6and2fokqess5tojy2u	335	17	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	335	18	very	very	RB
work_dbbvwgi6and2fokqess5tojy2u	335	19	sensitive	sensitive	JJ
work_dbbvwgi6and2fokqess5tojy2u	335	20	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	335	21	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	335	22	dysregulation	dysregulation	NN
work_dbbvwgi6and2fokqess5tojy2u	335	23	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	335	24	autophagy	autophagy	NN
work_dbbvwgi6and2fokqess5tojy2u	335	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	336	1	Although	although	IN
work_dbbvwgi6and2fokqess5tojy2u	336	2	more	more	JJR
work_dbbvwgi6and2fokqess5tojy2u	336	3	studies	study	NNS
work_dbbvwgi6and2fokqess5tojy2u	336	4	will	will	MD
work_dbbvwgi6and2fokqess5tojy2u	336	5	be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	336	6	necessary	necessary	JJ
work_dbbvwgi6and2fokqess5tojy2u	336	7	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	336	8	establish	establish	VB
work_dbbvwgi6and2fokqess5tojy2u	336	9	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	336	10	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	336	11	precise	precise	JJ
work_dbbvwgi6and2fokqess5tojy2u	336	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	336	13	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	336	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	336	15	autophagy	autophagy	NNP
work_dbbvwgi6and2fokqess5tojy2u	336	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	336	17	our	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	336	18	results	result	NNS
work_dbbvwgi6and2fokqess5tojy2u	336	19	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	336	20	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	336	21	agreement	agreement	NN
work_dbbvwgi6and2fokqess5tojy2u	336	22	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	336	23	these	these	DT
work_dbbvwgi6and2fokqess5tojy2u	336	24	previous	previous	JJ
work_dbbvwgi6and2fokqess5tojy2u	336	25	observations	observation	NNS
work_dbbvwgi6and2fokqess5tojy2u	336	26	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	336	27	other	other	JJ
work_dbbvwgi6and2fokqess5tojy2u	336	28	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	336	29	models	model	NNS
work_dbbvwgi6and2fokqess5tojy2u	336	30	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	336	31	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	336	32	reveal	reveal	VB
work_dbbvwgi6and2fokqess5tojy2u	336	33	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	336	34	dysregulation	dysregulation	NN
work_dbbvwgi6and2fokqess5tojy2u	336	35	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	336	36	autophagy	autophagy	NN
work_dbbvwgi6and2fokqess5tojy2u	336	37	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	336	38	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	336	39	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	336	40	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	336	41	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	337	1	A	a	DT
work_dbbvwgi6and2fokqess5tojy2u	337	2	recent	recent	JJ
work_dbbvwgi6and2fokqess5tojy2u	337	3	study	study	NN
work_dbbvwgi6and2fokqess5tojy2u	337	4	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	337	5	suggests	suggest	VBZ
work_dbbvwgi6and2fokqess5tojy2u	337	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	337	7	involvement	involvement	NN
work_dbbvwgi6and2fokqess5tojy2u	337	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	337	9	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	337	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	337	11	Parkinson	Parkinson	NNP
work_dbbvwgi6and2fokqess5tojy2u	337	12	’s	’s	POS
work_dbbvwgi6and2fokqess5tojy2u	337	13	disease	disease	NN
work_dbbvwgi6and2fokqess5tojy2u	337	14	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	337	15	58	58	CD
work_dbbvwgi6and2fokqess5tojy2u	337	16	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	337	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	337	18	it	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	337	19	would	would	MD
work_dbbvwgi6and2fokqess5tojy2u	337	20	be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	337	21	interesting	interesting	JJ
work_dbbvwgi6and2fokqess5tojy2u	337	22	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	337	23	analyze	analyze	VB
work_dbbvwgi6and2fokqess5tojy2u	337	24	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	337	25	future	future	JJ
work_dbbvwgi6and2fokqess5tojy2u	337	26	studies	study	NNS
work_dbbvwgi6and2fokqess5tojy2u	337	27	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	337	28	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	337	29	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	337	30	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	337	31	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	337	32	midbrain	midbrain	NN
work_dbbvwgi6and2fokqess5tojy2u	337	33	dopaminergic	dopaminergic	JJ
work_dbbvwgi6and2fokqess5tojy2u	337	34	neurons	neuron	NNS
work_dbbvwgi6and2fokqess5tojy2u	337	35	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	337	36	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	337	37	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	337	38	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	338	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	338	2	summary	summary	NN
work_dbbvwgi6and2fokqess5tojy2u	338	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	338	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	338	5	generation	generation	NN
work_dbbvwgi6and2fokqess5tojy2u	338	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	338	7	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	338	8	mutant	mutant	JJ
work_dbbvwgi6and2fokqess5tojy2u	338	9	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	338	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	338	11	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	338	12	led	lead	VBD
work_dbbvwgi6and2fokqess5tojy2u	338	13	us	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	338	14	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	338	15	identify	identify	VB
work_dbbvwgi6and2fokqess5tojy2u	338	16	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	338	17	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	338	18	ubiquitin	ubiquitin	NNP
work_dbbvwgi6and2fokqess5tojy2u	338	19	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	338	20	as	as	RB
work_dbbvwgi6and2fokqess5tojy2u	338	21	essential	essential	JJ
work_dbbvwgi6and2fokqess5tojy2u	338	22	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	338	23	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	338	24	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	338	25	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	338	26	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	338	27	important	important	JJ
work_dbbvwgi6and2fokqess5tojy2u	338	28	regulator	regulator	NN
work_dbbvwgi6and2fokqess5tojy2u	338	29	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	338	30	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	338	31	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	338	32	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	339	1	These	these	DT
work_dbbvwgi6and2fokqess5tojy2u	339	2	results	result	NNS
work_dbbvwgi6and2fokqess5tojy2u	339	3	may	may	MD
work_dbbvwgi6and2fokqess5tojy2u	339	4	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	339	5	explain	explain	VB
work_dbbvwgi6and2fokqess5tojy2u	339	6	some	some	DT
work_dbbvwgi6and2fokqess5tojy2u	339	7	features	feature	NNS
work_dbbvwgi6and2fokqess5tojy2u	339	8	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	339	9	among	among	IN
work_dbbvwgi6and2fokqess5tojy2u	339	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	339	11	Old	Old	NNP
work_dbbvwgi6and2fokqess5tojy2u	339	12	Order	Order	NNP
work_dbbvwgi6and2fokqess5tojy2u	339	13	Amish	amish	VBP
work_dbbvwgi6and2fokqess5tojy2u	339	14	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	339	15	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	339	16	homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	339	17	missense	missense	NN
work_dbbvwgi6and2fokqess5tojy2u	339	18	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	339	19	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	339	20	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	339	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	340	1	Future	future	JJ
work_dbbvwgi6and2fokqess5tojy2u	340	2	studies	study	NNS
work_dbbvwgi6and2fokqess5tojy2u	340	3	will	will	MD
work_dbbvwgi6and2fokqess5tojy2u	340	4	be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	340	5	necessary	necessary	JJ
work_dbbvwgi6and2fokqess5tojy2u	340	6	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	340	7	identify	identify	VB
work_dbbvwgi6and2fokqess5tojy2u	340	8	additional	additional	JJ
work_dbbvwgi6and2fokqess5tojy2u	340	9	partners	partner	NNS
work_dbbvwgi6and2fokqess5tojy2u	340	10	involved	involve	VBN
work_dbbvwgi6and2fokqess5tojy2u	340	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	340	12	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	340	13	physiology	physiology	NN
work_dbbvwgi6and2fokqess5tojy2u	340	14	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	340	15	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	340	16	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	340	17	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	340	18	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	340	19	diseases	disease	NNS
work_dbbvwgi6and2fokqess5tojy2u	340	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	341	1	MAtErIALs	material	NNS
work_dbbvwgi6and2fokqess5tojy2u	341	2	AND	and	CC
work_dbbvwgi6and2fokqess5tojy2u	341	3	MEtHODs	MEtHODs	NNP
work_dbbvwgi6and2fokqess5tojy2u	341	4	Animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	341	5	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	341	6	ES	ES	NNP
work_dbbvwgi6and2fokqess5tojy2u	341	7	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	341	8	line	line	NN
work_dbbvwgi6and2fokqess5tojy2u	341	9	AR0530	ar0530	NN
work_dbbvwgi6and2fokqess5tojy2u	341	10	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	341	11	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	341	12	Sanger	Sanger	NNP
work_dbbvwgi6and2fokqess5tojy2u	341	13	Institute	Institute	NNP
work_dbbvwgi6and2fokqess5tojy2u	341	14	containing	contain	VBG
work_dbbvwgi6and2fokqess5tojy2u	341	15	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	341	16	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	341	17	trap	trap	NN
work_dbbvwgi6and2fokqess5tojy2u	341	18	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	341	19	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	341	20	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	341	21	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	341	22	neomycin	neomycin	NNP
work_dbbvwgi6and2fokqess5tojy2u	341	23	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	341	24	β	β	NN
work_dbbvwgi6and2fokqess5tojy2u	341	25	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	341	26	geo-	geo-	NNP
work_dbbvwgi6and2fokqess5tojy2u	341	27	Neo	Neo	NNP
work_dbbvwgi6and2fokqess5tojy2u	341	28	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	341	29	cassette	cassette	NN
work_dbbvwgi6and2fokqess5tojy2u	341	30	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	341	31	has	have	VBZ
work_dbbvwgi6and2fokqess5tojy2u	341	32	integrated	integrate	VBN
work_dbbvwgi6and2fokqess5tojy2u	341	33	between	between	IN
work_dbbvwgi6and2fokqess5tojy2u	341	34	exons	exon	NNS
work_dbbvwgi6and2fokqess5tojy2u	341	35	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	341	36	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	341	37	3	3	CD
work_dbbvwgi6and2fokqess5tojy2u	341	38	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	341	39	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	341	40	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	341	41	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	341	42	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	341	43	used	use	VBN
work_dbbvwgi6and2fokqess5tojy2u	341	44	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	342	1	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	342	2	choose	choose	VBP
work_dbbvwgi6and2fokqess5tojy2u	342	3	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	342	4	ES	ES	NNP
work_dbbvwgi6and2fokqess5tojy2u	342	5	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	342	6	line	line	NN
work_dbbvwgi6and2fokqess5tojy2u	342	7	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	342	8	study	study	VB
work_dbbvwgi6and2fokqess5tojy2u	342	9	Herc2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	342	10	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	342	11	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	342	12	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	342	13	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	342	14	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	342	15	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	342	16	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	342	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	342	18	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	342	19	avoid	avoid	VB
work_dbbvwgi6and2fokqess5tojy2u	342	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	342	21	variability	variability	NN
work_dbbvwgi6and2fokqess5tojy2u	342	22	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	342	23	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	342	24	already	already	RB
work_dbbvwgi6and2fokqess5tojy2u	342	25	existing	exist	VBG
work_dbbvwgi6and2fokqess5tojy2u	342	26	Herc2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	342	27	mutations	mutation	NNS
work_dbbvwgi6and2fokqess5tojy2u	342	28	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	342	29	deletions	deletion	NNS
work_dbbvwgi6and2fokqess5tojy2u	342	30	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	342	31	point	point	NN
work_dbbvwgi6and2fokqess5tojy2u	342	32	mutations	mutation	NNS
work_dbbvwgi6and2fokqess5tojy2u	342	33	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	342	34	DNA	dna	NN
work_dbbvwgi6and2fokqess5tojy2u	342	35	rearrangements	rearrangement	NNS
work_dbbvwgi6and2fokqess5tojy2u	342	36	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	342	37	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	342	38	50	50	CD
work_dbbvwgi6and2fokqess5tojy2u	342	39	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	342	40	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	343	1	ES	es	NN
work_dbbvwgi6and2fokqess5tojy2u	343	2	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	343	3	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	343	4	injected	inject	VBN
work_dbbvwgi6and2fokqess5tojy2u	343	5	into	into	IN
work_dbbvwgi6and2fokqess5tojy2u	343	6	4.5	4.5	CD
work_dbbvwgi6and2fokqess5tojy2u	343	7	day	day	NN
work_dbbvwgi6and2fokqess5tojy2u	343	8	C57BL/6J	C57BL/6J	:
work_dbbvwgi6and2fokqess5tojy2u	343	9	blastocysts	blastocyst	NNS
work_dbbvwgi6and2fokqess5tojy2u	343	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	343	11	which	which	WDT
work_dbbvwgi6and2fokqess5tojy2u	343	12	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	343	13	then	then	RB
work_dbbvwgi6and2fokqess5tojy2u	343	14	implanted	implant	VBN
work_dbbvwgi6and2fokqess5tojy2u	343	15	into	into	IN
work_dbbvwgi6and2fokqess5tojy2u	343	16	pseudopregnant	pseudopregnant	JJ
work_dbbvwgi6and2fokqess5tojy2u	343	17	females	female	NNS
work_dbbvwgi6and2fokqess5tojy2u	343	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	344	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	344	2	resulting	result	VBG
work_dbbvwgi6and2fokqess5tojy2u	344	3	90	90	CD
work_dbbvwgi6and2fokqess5tojy2u	344	4	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	344	5	95	95	CD
work_dbbvwgi6and2fokqess5tojy2u	344	6	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	344	7	coat	coat	NN
work_dbbvwgi6and2fokqess5tojy2u	344	8	color	color	NN
work_dbbvwgi6and2fokqess5tojy2u	344	9	chimeras	chimera	NNS
work_dbbvwgi6and2fokqess5tojy2u	344	10	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	344	11	crossed	cross	VBN
work_dbbvwgi6and2fokqess5tojy2u	344	12	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	344	13	C57BL/6	c57bl/6	CD
work_dbbvwgi6and2fokqess5tojy2u	344	14	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	344	15	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	344	16	generate	generate	VB
work_dbbvwgi6and2fokqess5tojy2u	344	17	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	344	18	heterozygous	heterozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	344	19	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	344	20	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	344	21	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	344	22	Herc2530	herc2530	CD
work_dbbvwgi6and2fokqess5tojy2u	344	23	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	344	24	Herc2+/530	Herc2+/530	NNP
work_dbbvwgi6and2fokqess5tojy2u	344	25	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	344	26	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	345	1	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	345	2	knockout	knockout	NN
work_dbbvwgi6and2fokqess5tojy2u	345	3	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	345	4	B6.129S2-Trp53tm1Tyj	B6.129S2-Trp53tm1Tyj	NNP
work_dbbvwgi6and2fokqess5tojy2u	345	5	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	345	6	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	345	7	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	345	8	Jackson	Jackson	NNP
work_dbbvwgi6and2fokqess5tojy2u	345	9	laboratories	laboratory	NNS
work_dbbvwgi6and2fokqess5tojy2u	345	10	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	345	11	37	37	CD
work_dbbvwgi6and2fokqess5tojy2u	345	12	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	345	13	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	345	14	kindly	kindly	RB
work_dbbvwgi6and2fokqess5tojy2u	345	15	provided	provide	VBN
work_dbbvwgi6and2fokqess5tojy2u	345	16	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	345	17	Dr.	Dr.	NNP
work_dbbvwgi6and2fokqess5tojy2u	345	18	J.	J.	NNP
work_dbbvwgi6and2fokqess5tojy2u	345	19	Martin-	Martin-	NNP
work_dbbvwgi6and2fokqess5tojy2u	345	20	Caballero	Caballero	NNP
work_dbbvwgi6and2fokqess5tojy2u	345	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	346	1	All	all	DT
work_dbbvwgi6and2fokqess5tojy2u	346	2	animal	animal	NN
work_dbbvwgi6and2fokqess5tojy2u	346	3	experiments	experiment	NNS
work_dbbvwgi6and2fokqess5tojy2u	346	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	346	5	performed	perform	VBN
work_dbbvwgi6and2fokqess5tojy2u	346	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	346	7	accordance	accordance	NN
work_dbbvwgi6and2fokqess5tojy2u	346	8	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	346	9	guidelines	guideline	NNS
work_dbbvwgi6and2fokqess5tojy2u	346	10	approved	approve	VBN
work_dbbvwgi6and2fokqess5tojy2u	346	11	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	346	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	346	13	Ethical	Ethical	NNP
work_dbbvwgi6and2fokqess5tojy2u	346	14	Committee	Committee	NNP
work_dbbvwgi6and2fokqess5tojy2u	346	15	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	346	16	Animal	Animal	NNP
work_dbbvwgi6and2fokqess5tojy2u	346	17	Experimentation	Experimentation	NNP
work_dbbvwgi6and2fokqess5tojy2u	346	18	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	346	19	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	346	20	University	University	NNP
work_dbbvwgi6and2fokqess5tojy2u	346	21	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	346	22	Barcelona	Barcelona	NNP
work_dbbvwgi6and2fokqess5tojy2u	346	23	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	347	1	Genotyping	Genotyping	NNP
work_dbbvwgi6and2fokqess5tojy2u	347	2	Tail	Tail	NNP
work_dbbvwgi6and2fokqess5tojy2u	347	3	DNA	dna	NN
work_dbbvwgi6and2fokqess5tojy2u	347	4	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	347	5	embryo	embryo	NN
work_dbbvwgi6and2fokqess5tojy2u	347	6	samples	sample	NNS
work_dbbvwgi6and2fokqess5tojy2u	347	7	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	347	8	purified	purify	VBN
work_dbbvwgi6and2fokqess5tojy2u	347	9	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	347	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	347	11	NucleoSpin	NucleoSpin	NNP
work_dbbvwgi6and2fokqess5tojy2u	347	12	Tissue	Tissue	NNP
work_dbbvwgi6and2fokqess5tojy2u	347	13	kit	kit	NN
work_dbbvwgi6and2fokqess5tojy2u	347	14	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	347	15	MACHEREY-	MACHEREY-	NNP
work_dbbvwgi6and2fokqess5tojy2u	347	16	NAGEL	NAGEL	NNP
work_dbbvwgi6and2fokqess5tojy2u	347	17	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	347	18	according	accord	VBG
work_dbbvwgi6and2fokqess5tojy2u	347	19	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	347	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	347	21	manufacturer	manufacturer	NN
work_dbbvwgi6and2fokqess5tojy2u	347	22	’s	’s	POS
work_dbbvwgi6and2fokqess5tojy2u	347	23	protocol	protocol	NN
work_dbbvwgi6and2fokqess5tojy2u	347	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	348	1	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	348	2	amplification	amplification	NN
work_dbbvwgi6and2fokqess5tojy2u	348	3	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	348	4	performed	perform	VBN
work_dbbvwgi6and2fokqess5tojy2u	348	5	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	348	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	348	7	primers	primer	NNS
work_dbbvwgi6and2fokqess5tojy2u	348	8	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	348	9	530KO1	530ko1	CD
work_dbbvwgi6and2fokqess5tojy2u	348	10	5’GGCTGCCCAGTCTCGCCTTG3	5’ggctgcccagtctcgccttg3	CD
work_dbbvwgi6and2fokqess5tojy2u	348	11	’	'	''
work_dbbvwgi6and2fokqess5tojy2u	348	12	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	348	13	530KO04	530ko04	CD
work_dbbvwgi6and2fokqess5tojy2u	348	14	5’CTGTCACCTCTCCGGGAGAAC3	5’CTGTCACCTCTCCGGGAGAAC3	NNP
work_dbbvwgi6and2fokqess5tojy2u	348	15	’	'	''
work_dbbvwgi6and2fokqess5tojy2u	348	16	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	348	17	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	348	18	amplification	amplification	NN
work_dbbvwgi6and2fokqess5tojy2u	348	19	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	348	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	348	21	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	348	22	wild	wild	JJ
work_dbbvwgi6and2fokqess5tojy2u	348	23	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	348	24	type	type	NN
work_dbbvwgi6and2fokqess5tojy2u	348	25	allele	allele	NN
work_dbbvwgi6and2fokqess5tojy2u	348	26	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	348	27	Gal7	Gal7	NNP
work_dbbvwgi6and2fokqess5tojy2u	348	28	5’TTTCCATATGGGGATTGGTG3	5’TTTCCATATGGGGATTGGTG3	NNP
work_dbbvwgi6and2fokqess5tojy2u	348	29	’	'	''
work_dbbvwgi6and2fokqess5tojy2u	348	30	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	348	31	Gal8	Gal8	NNP
work_dbbvwgi6and2fokqess5tojy2u	348	32	5’TGTCTGTTGTGCCCAGTCAT3	5’TGTCTGTTGTGCCCAGTCAT3	NNP
work_dbbvwgi6and2fokqess5tojy2u	348	33	’	'	''
work_dbbvwgi6and2fokqess5tojy2u	348	34	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	348	35	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	348	36	Herc2	herc2	CD
work_dbbvwgi6and2fokqess5tojy2u	348	37	530	530	CD
work_dbbvwgi6and2fokqess5tojy2u	348	38	allele	allele	NNS
work_dbbvwgi6and2fokqess5tojy2u	348	39	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	348	40	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	348	41	p53036	p53036	JJ
work_dbbvwgi6and2fokqess5tojy2u	348	42	5’ACAGCGTGGTGGTACCT3	5’acagcgtggtggtacct3	CD
work_dbbvwgi6and2fokqess5tojy2u	348	43	’	'	''
work_dbbvwgi6and2fokqess5tojy2u	348	44	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	348	45	p53037	p53037	NN
work_dbbvwgi6and2fokqess5tojy2u	348	46	5’TATACTCAGAGCCGGCCT	5’tatactcagagccggcct	CD
work_dbbvwgi6and2fokqess5tojy2u	348	47	p53038	p53038	NN
work_dbbvwgi6and2fokqess5tojy2u	348	48	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	348	49	’	'	''
work_dbbvwgi6and2fokqess5tojy2u	348	50	CTATCAAGGCATAGCGTTGG	CTATCAAGGCATAGCGTTGG	NNS
work_dbbvwgi6and2fokqess5tojy2u	348	51	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	348	52	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	348	53	genotype	genotype	NN
work_dbbvwgi6and2fokqess5tojy2u	348	54	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	348	55	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	348	56	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	349	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	349	2	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	349	3	settings	setting	NNS
work_dbbvwgi6and2fokqess5tojy2u	349	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	349	5	94	94	CD
work_dbbvwgi6and2fokqess5tojy2u	349	6	°	°	,
work_dbbvwgi6and2fokqess5tojy2u	349	7	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	349	8	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	349	9	3	3	CD
work_dbbvwgi6and2fokqess5tojy2u	349	10	minutes	minute	NNS
work_dbbvwgi6and2fokqess5tojy2u	349	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	349	12	94	94	CD
work_dbbvwgi6and2fokqess5tojy2u	349	13	°	°	,
work_dbbvwgi6and2fokqess5tojy2u	349	14	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	349	15	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	349	16	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	349	17	minute	minute	NN
work_dbbvwgi6and2fokqess5tojy2u	349	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	349	19	annealing	anneal	VBG
work_dbbvwgi6and2fokqess5tojy2u	349	20	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	349	21	60	60	CD
work_dbbvwgi6and2fokqess5tojy2u	349	22	°	°	,
work_dbbvwgi6and2fokqess5tojy2u	349	23	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	349	24	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	349	25	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	349	26	minute	minute	NN
work_dbbvwgi6and2fokqess5tojy2u	349	27	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	349	28	elongation	elongation	NN
work_dbbvwgi6and2fokqess5tojy2u	349	29	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	349	30	Oncotarget56101www.impactjournals.com/oncotarget	oncotarget56101www.impactjournals.com/oncotarget	CD
work_dbbvwgi6and2fokqess5tojy2u	349	31	72	72	CD
work_dbbvwgi6and2fokqess5tojy2u	349	32	°	°	,
work_dbbvwgi6and2fokqess5tojy2u	349	33	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	349	34	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	349	35	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	349	36	minute	minute	NN
work_dbbvwgi6and2fokqess5tojy2u	349	37	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	349	38	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	349	39	35	35	CD
work_dbbvwgi6and2fokqess5tojy2u	349	40	cycles	cycle	NNS
work_dbbvwgi6and2fokqess5tojy2u	349	41	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	350	1	rt	rt	NNP
work_dbbvwgi6and2fokqess5tojy2u	350	2	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	350	3	Pcr	Pcr	NNP
work_dbbvwgi6and2fokqess5tojy2u	350	4	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	350	5	assess	assess	VB
work_dbbvwgi6and2fokqess5tojy2u	350	6	trap	trap	NN
work_dbbvwgi6and2fokqess5tojy2u	350	7	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	350	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	350	9	total	total	JJ
work_dbbvwgi6and2fokqess5tojy2u	350	10	RNA	RNA	NNP
work_dbbvwgi6and2fokqess5tojy2u	350	11	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	350	12	isolated	isolate	VBN
work_dbbvwgi6and2fokqess5tojy2u	350	13	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	350	14	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	350	15	tissues	tissue	NNS
work_dbbvwgi6and2fokqess5tojy2u	350	16	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	350	17	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	350	18	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	350	19	TRIsure	trisure	NN
work_dbbvwgi6and2fokqess5tojy2u	350	20	reagent	reagent	NN
work_dbbvwgi6and2fokqess5tojy2u	350	21	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	350	22	Bioline	Bioline	NNP
work_dbbvwgi6and2fokqess5tojy2u	350	23	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	350	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	351	1	Two	two	CD
work_dbbvwgi6and2fokqess5tojy2u	351	2	µg	µg	IN
work_dbbvwgi6and2fokqess5tojy2u	351	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	351	4	total	total	NN
work_dbbvwgi6and2fokqess5tojy2u	351	5	RNA	RNA	NNP
work_dbbvwgi6and2fokqess5tojy2u	351	6	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	351	7	reverse	reverse	RB
work_dbbvwgi6and2fokqess5tojy2u	351	8	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	351	9	transcribed	transcribe	VBN
work_dbbvwgi6and2fokqess5tojy2u	351	10	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	351	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	351	12	cDNA	cdna	NN
work_dbbvwgi6and2fokqess5tojy2u	351	13	Reverse	Reverse	NNP
work_dbbvwgi6and2fokqess5tojy2u	351	14	Transcription	Transcription	NNP
work_dbbvwgi6and2fokqess5tojy2u	351	15	kit	kit	NN
work_dbbvwgi6and2fokqess5tojy2u	351	16	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	351	17	Applied	Applied	NNP
work_dbbvwgi6and2fokqess5tojy2u	351	18	Biosystems	Biosystems	NNPS
work_dbbvwgi6and2fokqess5tojy2u	351	19	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	351	20	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	351	21	random	random	JJ
work_dbbvwgi6and2fokqess5tojy2u	351	22	primers	primer	NNS
work_dbbvwgi6and2fokqess5tojy2u	351	23	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	352	1	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	352	2	assess	assess	VB
work_dbbvwgi6and2fokqess5tojy2u	352	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	352	4	trap	trap	NN
work_dbbvwgi6and2fokqess5tojy2u	352	5	insertion	insertion	NN
work_dbbvwgi6and2fokqess5tojy2u	352	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	352	7	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	352	8	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	352	9	carried	carry	VBN
work_dbbvwgi6and2fokqess5tojy2u	352	10	out	out	RP
work_dbbvwgi6and2fokqess5tojy2u	352	11	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	352	12	primers	primer	NNS
work_dbbvwgi6and2fokqess5tojy2u	352	13	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	352	14	530KO02	530ko02	CD
work_dbbvwgi6and2fokqess5tojy2u	352	15	5’CAGGTCTGACCACCCGGAGG3	5’caggtctgaccacccggagg3	CD
work_dbbvwgi6and2fokqess5tojy2u	352	16	’	'	''
work_dbbvwgi6and2fokqess5tojy2u	352	17	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	352	18	530KO09	530ko09	LS
work_dbbvwgi6and2fokqess5tojy2u	352	19	5’GGGAGTTCTCGATTTTGTGC3	5’gggagttctcgattttgtgc3	NN
work_dbbvwgi6and2fokqess5tojy2u	352	20	’	'	''
work_dbbvwgi6and2fokqess5tojy2u	352	21	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	352	22	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	352	23	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	352	24	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	352	25	geo40/60	geo40/60	NNP
work_dbbvwgi6and2fokqess5tojy2u	352	26	5’AGGGTTTTCCCAGTCACGAC3	5’AGGGTTTTCCCAGTCACGAC3	NNP
work_dbbvwgi6and2fokqess5tojy2u	352	27	’	'	''
work_dbbvwgi6and2fokqess5tojy2u	352	28	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	353	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	353	2	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	353	3	settings	setting	NNS
work_dbbvwgi6and2fokqess5tojy2u	353	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	353	5	94	94	CD
work_dbbvwgi6and2fokqess5tojy2u	353	6	°	°	,
work_dbbvwgi6and2fokqess5tojy2u	353	7	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	353	8	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	353	9	3	3	CD
work_dbbvwgi6and2fokqess5tojy2u	353	10	minutes	minute	NNS
work_dbbvwgi6and2fokqess5tojy2u	353	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	353	12	94	94	CD
work_dbbvwgi6and2fokqess5tojy2u	353	13	°	°	,
work_dbbvwgi6and2fokqess5tojy2u	353	14	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	353	15	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	353	16	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	353	17	minute	minute	NN
work_dbbvwgi6and2fokqess5tojy2u	353	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	353	19	annealing	anneal	VBG
work_dbbvwgi6and2fokqess5tojy2u	353	20	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	353	21	55	55	CD
work_dbbvwgi6and2fokqess5tojy2u	353	22	°	°	,
work_dbbvwgi6and2fokqess5tojy2u	353	23	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	353	24	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	353	25	30	30	CD
work_dbbvwgi6and2fokqess5tojy2u	353	26	seconds	second	NNS
work_dbbvwgi6and2fokqess5tojy2u	353	27	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	353	28	elongation	elongation	NN
work_dbbvwgi6and2fokqess5tojy2u	353	29	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	353	30	72	72	CD
work_dbbvwgi6and2fokqess5tojy2u	353	31	°	°	NNS
work_dbbvwgi6and2fokqess5tojy2u	353	32	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	353	33	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	353	34	45	45	CD
work_dbbvwgi6and2fokqess5tojy2u	353	35	seconds	second	NNS
work_dbbvwgi6and2fokqess5tojy2u	353	36	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	353	37	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	353	38	30	30	CD
work_dbbvwgi6and2fokqess5tojy2u	353	39	cycles	cycle	NNS
work_dbbvwgi6and2fokqess5tojy2u	353	40	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	354	1	Additionally	additionally	RB
work_dbbvwgi6and2fokqess5tojy2u	354	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	354	3	cDNA	cdna	NN
work_dbbvwgi6and2fokqess5tojy2u	354	4	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	354	5	sequenced	sequence	VBN
work_dbbvwgi6and2fokqess5tojy2u	354	6	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	354	7	BigDye	BigDye	NNP
work_dbbvwgi6and2fokqess5tojy2u	354	8	3.1	3.1	CD
work_dbbvwgi6and2fokqess5tojy2u	354	9	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	354	10	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	354	11	ABI	ABI	NNP
work_dbbvwgi6and2fokqess5tojy2u	354	12	3130XL	3130xl	CD
work_dbbvwgi6and2fokqess5tojy2u	354	13	genetic	genetic	JJ
work_dbbvwgi6and2fokqess5tojy2u	354	14	analyzer	analyzer	NN
work_dbbvwgi6and2fokqess5tojy2u	354	15	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	354	16	Applied	Applied	NNP
work_dbbvwgi6and2fokqess5tojy2u	354	17	Biosystems	Biosystems	NNP
work_dbbvwgi6and2fokqess5tojy2u	354	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	354	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	355	1	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	355	2	analyze	analyze	VB
work_dbbvwgi6and2fokqess5tojy2u	355	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	355	4	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	355	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	355	6	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	355	7	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	355	8	RT	RT	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	9	quantitative	quantitative	NN
work_dbbvwgi6and2fokqess5tojy2u	355	10	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	11	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	355	12	carried	carry	VBN
work_dbbvwgi6and2fokqess5tojy2u	355	13	out	out	RP
work_dbbvwgi6and2fokqess5tojy2u	355	14	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	355	15	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	355	16	ABI	ABI	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	17	Prism	Prism	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	18	7900	7900	CD
work_dbbvwgi6and2fokqess5tojy2u	355	19	HT	HT	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	20	fast	fast	JJ
work_dbbvwgi6and2fokqess5tojy2u	355	21	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	355	22	real	real	JJ
work_dbbvwgi6and2fokqess5tojy2u	355	23	Time	Time	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	24	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	25	system	system	NN
work_dbbvwgi6and2fokqess5tojy2u	355	26	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	355	27	commercially	commercially	RB
work_dbbvwgi6and2fokqess5tojy2u	355	28	available	available	JJ
work_dbbvwgi6and2fokqess5tojy2u	355	29	Taqman	Taqman	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	30	assays	assays	RB
work_dbbvwgi6and2fokqess5tojy2u	355	31	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	355	32	Applied	Applied	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	33	Biosystems	Biosystems	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	34	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	355	35	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	355	36	CDKN1A	CDKN1A	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	37	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	355	38	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	355	39	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	355	40	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	355	41	Mm04205640_g1	Mm04205640_g1	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	42	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	355	43	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	355	44	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	355	45	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	355	46	Hs00355783	Hs00355783	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	47	_	_	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	48	m1	m1	NN
work_dbbvwgi6and2fokqess5tojy2u	355	49	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	355	50	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	355	51	GAPDH	GAPDH	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	52	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	355	53	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	355	54	GAPDH	GAPDH	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	55	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	355	56	Mm99999915_g1	Mm99999915_g1	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	57	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	355	58	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	355	59	GAPDH	GAPDH	NNS
work_dbbvwgi6and2fokqess5tojy2u	355	60	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	355	61	Hs99999905_m1	Hs99999905_m1	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	62	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	355	63	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	355	64	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	355	65	18S	18S	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	66	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	355	67	Hs99999901_s1	Hs99999901_s1	NNP
work_dbbvwgi6and2fokqess5tojy2u	355	68	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	355	69	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	356	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	356	2	PCR	PCR	NNP
work_dbbvwgi6and2fokqess5tojy2u	356	3	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	356	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	356	5	captured	capture	VBN
work_dbbvwgi6and2fokqess5tojy2u	356	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	356	7	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	356	8	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	356	9	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	356	10	Sequence	Sequence	NNP
work_dbbvwgi6and2fokqess5tojy2u	356	11	Detector	Detector	NNP
work_dbbvwgi6and2fokqess5tojy2u	356	12	software	software	NN
work_dbbvwgi6and2fokqess5tojy2u	356	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	356	14	SDS	sds	NN
work_dbbvwgi6and2fokqess5tojy2u	356	15	version	version	NN
work_dbbvwgi6and2fokqess5tojy2u	356	16	2.3	2.3	CD
work_dbbvwgi6and2fokqess5tojy2u	356	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	356	18	Applied	Applied	NNP
work_dbbvwgi6and2fokqess5tojy2u	356	19	Biosystems	Biosystems	NNPS
work_dbbvwgi6and2fokqess5tojy2u	356	20	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	356	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	357	1	Histology	histology	NN
work_dbbvwgi6and2fokqess5tojy2u	357	2	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	357	3	immunochemistry	immunochemistry	NN
work_dbbvwgi6and2fokqess5tojy2u	357	4	X	x	NN
work_dbbvwgi6and2fokqess5tojy2u	357	5	-	-	NN
work_dbbvwgi6and2fokqess5tojy2u	357	6	gal	gal	NNP
work_dbbvwgi6and2fokqess5tojy2u	357	7	staining	staining	NN
work_dbbvwgi6and2fokqess5tojy2u	357	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	357	9	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	357	10	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	357	11	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	357	12	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	357	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	358	1	Mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	358	2	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	358	3	anesthetized	anesthetize	VBN
work_dbbvwgi6and2fokqess5tojy2u	358	4	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	358	5	perfused	perfuse	VBN
work_dbbvwgi6and2fokqess5tojy2u	358	6	via	via	IN
work_dbbvwgi6and2fokqess5tojy2u	358	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	358	8	left	left	JJ
work_dbbvwgi6and2fokqess5tojy2u	358	9	ventricle	ventricle	NN
work_dbbvwgi6and2fokqess5tojy2u	358	10	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	358	11	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	358	12	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	358	13	paraformaldehyde	paraformaldehyde	NN
work_dbbvwgi6and2fokqess5tojy2u	358	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	358	15	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	358	16	phosphate	phosphate	NN
work_dbbvwgi6and2fokqess5tojy2u	358	17	buffer	buffer	NN
work_dbbvwgi6and2fokqess5tojy2u	358	18	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	358	19	0.12	0.12	CD
work_dbbvwgi6and2fokqess5tojy2u	358	20	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	358	21	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	358	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	359	1	All	all	DT
work_dbbvwgi6and2fokqess5tojy2u	359	2	tissues	tissue	NNS
work_dbbvwgi6and2fokqess5tojy2u	359	3	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	359	4	dissected	dissect	VBN
work_dbbvwgi6and2fokqess5tojy2u	359	5	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	359	6	fixed	fix	VBN
work_dbbvwgi6and2fokqess5tojy2u	359	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	359	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	359	9	same	same	JJ
work_dbbvwgi6and2fokqess5tojy2u	359	10	solution	solution	NN
work_dbbvwgi6and2fokqess5tojy2u	359	11	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	359	12	3	3	CD
work_dbbvwgi6and2fokqess5tojy2u	359	13	hours	hour	NNS
work_dbbvwgi6and2fokqess5tojy2u	359	14	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	359	15	4ºC	4ºc	CD
work_dbbvwgi6and2fokqess5tojy2u	359	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	359	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	359	18	later	later	RB
work_dbbvwgi6and2fokqess5tojy2u	359	19	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	359	20	cryopreserved	cryopreserve	VBN
work_dbbvwgi6and2fokqess5tojy2u	359	21	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	359	22	immersion	immersion	NN
work_dbbvwgi6and2fokqess5tojy2u	359	23	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	359	24	30	30	CD
work_dbbvwgi6and2fokqess5tojy2u	359	25	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	359	26	sucrose	sucrose	NN
work_dbbvwgi6and2fokqess5tojy2u	359	27	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	359	28	48	48	CD
work_dbbvwgi6and2fokqess5tojy2u	359	29	h	h	NNS
work_dbbvwgi6and2fokqess5tojy2u	359	30	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	359	31	4ºC.	4ºc.	CD
work_dbbvwgi6and2fokqess5tojy2u	360	1	Whole	whole	JJ
work_dbbvwgi6and2fokqess5tojy2u	360	2	tissues	tissue	NNS
work_dbbvwgi6and2fokqess5tojy2u	360	3	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	360	4	then	then	RB
work_dbbvwgi6and2fokqess5tojy2u	360	5	embedded	embed	VBN
work_dbbvwgi6and2fokqess5tojy2u	360	6	into	into	IN
work_dbbvwgi6and2fokqess5tojy2u	360	7	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	360	8	8	8	CD
work_dbbvwgi6and2fokqess5tojy2u	360	9	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	360	10	gelatin	gelatin	NN
work_dbbvwgi6and2fokqess5tojy2u	360	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	360	12	15	15	CD
work_dbbvwgi6and2fokqess5tojy2u	360	13	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	360	14	sucrose	sucrose	JJ
work_dbbvwgi6and2fokqess5tojy2u	360	15	solution	solution	NN
work_dbbvwgi6and2fokqess5tojy2u	360	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	360	17	frozen	freeze	VBN
work_dbbvwgi6and2fokqess5tojy2u	360	18	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	360	19	liquid	liquid	JJ
work_dbbvwgi6and2fokqess5tojy2u	360	20	nitrogen	nitrogen	NN
work_dbbvwgi6and2fokqess5tojy2u	360	21	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	360	22	stored	store	VBD
work_dbbvwgi6and2fokqess5tojy2u	360	23	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	360	24	-80ºC.	-80ºC.	.
work_dbbvwgi6and2fokqess5tojy2u	361	1	Before	before	IN
work_dbbvwgi6and2fokqess5tojy2u	361	2	staining	stain	VBG
work_dbbvwgi6and2fokqess5tojy2u	361	3	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	361	4	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	361	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	361	6	galactosidase	galactosidase	NNP
work_dbbvwgi6and2fokqess5tojy2u	361	7	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	361	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	361	9	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	361	10	tissues	tissue	NNS
work_dbbvwgi6and2fokqess5tojy2u	361	11	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	361	12	sliced	slice	VBN
work_dbbvwgi6and2fokqess5tojy2u	361	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	361	14	7	7	CD
work_dbbvwgi6and2fokqess5tojy2u	361	15	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	361	16	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	361	17	μm	μm	NN
work_dbbvwgi6and2fokqess5tojy2u	361	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	361	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	361	20	prepared	prepare	VBN
work_dbbvwgi6and2fokqess5tojy2u	361	21	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	361	22	polylysinated	polylysinate	VBN
work_dbbvwgi6and2fokqess5tojy2u	361	23	slides	slide	NNS
work_dbbvwgi6and2fokqess5tojy2u	361	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	361	25	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	361	26	permeabilized	permeabilize	VBN
work_dbbvwgi6and2fokqess5tojy2u	361	27	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	361	28	PBS-0.3	pbs-0.3	RB
work_dbbvwgi6and2fokqess5tojy2u	361	29	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	361	30	Triton	Triton	NNP
work_dbbvwgi6and2fokqess5tojy2u	361	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	362	1	After	after	IN
work_dbbvwgi6and2fokqess5tojy2u	362	2	washing	wash	VBG
work_dbbvwgi6and2fokqess5tojy2u	362	3	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	362	4	PBS	PBS	NNP
work_dbbvwgi6and2fokqess5tojy2u	362	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	362	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	362	7	slices	slice	NNS
work_dbbvwgi6and2fokqess5tojy2u	362	8	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	362	9	incubated	incubate	VBN
work_dbbvwgi6and2fokqess5tojy2u	362	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	362	11	staining	stain	VBG
work_dbbvwgi6and2fokqess5tojy2u	362	12	solution	solution	NN
work_dbbvwgi6and2fokqess5tojy2u	362	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	362	14	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	362	15	mM	mM	NNP
work_dbbvwgi6and2fokqess5tojy2u	362	16	X	x	NN
work_dbbvwgi6and2fokqess5tojy2u	362	17	-	-	NN
work_dbbvwgi6and2fokqess5tojy2u	362	18	gal	gal	NN
work_dbbvwgi6and2fokqess5tojy2u	362	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	362	20	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	362	21	mM	mM	NNP
work_dbbvwgi6and2fokqess5tojy2u	362	22	K4Fe(CN)6	K4Fe(CN)6	NNP
work_dbbvwgi6and2fokqess5tojy2u	362	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	362	24	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	362	25	mM	mM	NNP
work_dbbvwgi6and2fokqess5tojy2u	362	26	K3Fe(CN)6	K3Fe(CN)6	NNP
work_dbbvwgi6and2fokqess5tojy2u	362	27	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	362	28	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	362	29	mM	mM	NNP
work_dbbvwgi6and2fokqess5tojy2u	362	30	MgCl2	mgcl2	NN
work_dbbvwgi6and2fokqess5tojy2u	362	31	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	362	32	PBS	PBS	NNP
work_dbbvwgi6and2fokqess5tojy2u	362	33	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	362	34	overnight	overnight	RB
work_dbbvwgi6and2fokqess5tojy2u	362	35	while	while	IN
work_dbbvwgi6and2fokqess5tojy2u	362	36	shaking	shake	VBG
work_dbbvwgi6and2fokqess5tojy2u	362	37	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	362	38	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	362	39	dark	dark	NN
work_dbbvwgi6and2fokqess5tojy2u	362	40	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	362	41	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	362	42	°	°	NNS
work_dbbvwgi6and2fokqess5tojy2u	362	43	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	362	44	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	363	1	After	after	IN
work_dbbvwgi6and2fokqess5tojy2u	363	2	washing	wash	VBG
work_dbbvwgi6and2fokqess5tojy2u	363	3	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	363	4	PBS	PBS	NNP
work_dbbvwgi6and2fokqess5tojy2u	363	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	363	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	363	7	slices	slice	NNS
work_dbbvwgi6and2fokqess5tojy2u	363	8	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	363	9	stained	stain	VBN
work_dbbvwgi6and2fokqess5tojy2u	363	10	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	363	11	neutral	neutral	JJ
work_dbbvwgi6and2fokqess5tojy2u	363	12	red	red	NN
work_dbbvwgi6and2fokqess5tojy2u	363	13	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	363	14	mounted	mount	VBN
work_dbbvwgi6and2fokqess5tojy2u	363	15	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	363	16	microscopic	microscopic	JJ
work_dbbvwgi6and2fokqess5tojy2u	363	17	observation	observation	NN
work_dbbvwgi6and2fokqess5tojy2u	363	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	364	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	364	2	protocol	protocol	NN
work_dbbvwgi6and2fokqess5tojy2u	364	3	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	364	4	study	study	VB
work_dbbvwgi6and2fokqess5tojy2u	364	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	364	6	cerebellar	cerebellar	JJ
work_dbbvwgi6and2fokqess5tojy2u	364	7	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	364	8	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	364	9	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	364	10	reported	report	VBN
work_dbbvwgi6and2fokqess5tojy2u	364	11	previously	previously	RB
work_dbbvwgi6and2fokqess5tojy2u	364	12	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	364	13	46	46	CD
work_dbbvwgi6and2fokqess5tojy2u	364	14	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	364	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	365	1	Briefly	briefly	RB
work_dbbvwgi6and2fokqess5tojy2u	365	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	365	3	two	two	CD
work_dbbvwgi6and2fokqess5tojy2u	365	4	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	365	5	nine	nine	CD
work_dbbvwgi6and2fokqess5tojy2u	365	6	month	month	NN
work_dbbvwgi6and2fokqess5tojy2u	365	7	old	old	JJ
work_dbbvwgi6and2fokqess5tojy2u	365	8	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	365	9	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	365	10	deeply	deeply	RB
work_dbbvwgi6and2fokqess5tojy2u	365	11	anaesthetised	anaesthetise	VBN
work_dbbvwgi6and2fokqess5tojy2u	365	12	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	365	13	pentobarbital	pentobarbital	NN
work_dbbvwgi6and2fokqess5tojy2u	365	14	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	365	15	80	80	CD
work_dbbvwgi6and2fokqess5tojy2u	365	16	mg	mg	NNP
work_dbbvwgi6and2fokqess5tojy2u	365	17	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	365	18	kg	kg	NNP
work_dbbvwgi6and2fokqess5tojy2u	365	19	i.p	i.p	NNP
work_dbbvwgi6and2fokqess5tojy2u	365	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	366	1	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	366	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	366	3	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	366	4	perfused	perfuse	VBD
work_dbbvwgi6and2fokqess5tojy2u	366	5	transcardially	transcardially	RB
work_dbbvwgi6and2fokqess5tojy2u	366	6	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	366	7	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	366	8	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	366	9	paraformaldehyde	paraformaldehyde	NN
work_dbbvwgi6and2fokqess5tojy2u	366	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	366	11	0.12	0.12	NNP
work_dbbvwgi6and2fokqess5tojy2u	366	12	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	366	13	phosphate	phosphate	NN
work_dbbvwgi6and2fokqess5tojy2u	366	14	buffer	buffer	NN
work_dbbvwgi6and2fokqess5tojy2u	366	15	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	366	16	PB	PB	NNP
work_dbbvwgi6and2fokqess5tojy2u	366	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	366	18	pH	pH	NNP
work_dbbvwgi6and2fokqess5tojy2u	366	19	7.2	7.2	CD
work_dbbvwgi6and2fokqess5tojy2u	366	20	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	366	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	367	1	After	after	IN
work_dbbvwgi6and2fokqess5tojy2u	367	2	dissection	dissection	NN
work_dbbvwgi6and2fokqess5tojy2u	367	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	367	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	367	5	brains	brain	NNS
work_dbbvwgi6and2fokqess5tojy2u	367	6	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	367	7	post-	post-	NNP
work_dbbvwgi6and2fokqess5tojy2u	367	8	fixed	fix	VBN
work_dbbvwgi6and2fokqess5tojy2u	367	9	overnight	overnight	RB
work_dbbvwgi6and2fokqess5tojy2u	367	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	367	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	367	12	same	same	JJ
work_dbbvwgi6and2fokqess5tojy2u	367	13	fixative	fixative	JJ
work_dbbvwgi6and2fokqess5tojy2u	367	14	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	367	15	transferred	transfer	VBN
work_dbbvwgi6and2fokqess5tojy2u	367	16	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	367	17	30	30	CD
work_dbbvwgi6and2fokqess5tojy2u	367	18	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	367	19	sucrose	sucrose	NN
work_dbbvwgi6and2fokqess5tojy2u	367	20	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	367	21	PB	PB	NNP
work_dbbvwgi6and2fokqess5tojy2u	367	22	until	until	IN
work_dbbvwgi6and2fokqess5tojy2u	367	23	they	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	367	24	sank	sink	VBD
work_dbbvwgi6and2fokqess5tojy2u	367	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	368	1	Sagittal	sagittal	JJ
work_dbbvwgi6and2fokqess5tojy2u	368	2	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	368	3	coronal	coronal	JJ
work_dbbvwgi6and2fokqess5tojy2u	368	4	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	368	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	368	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	368	7	cerebellum	cerebellum	NN
work_dbbvwgi6and2fokqess5tojy2u	368	8	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	368	9	40	40	CD
work_dbbvwgi6and2fokqess5tojy2u	368	10	µm	µm	NNP
work_dbbvwgi6and2fokqess5tojy2u	368	11	thick	thick	JJ
work_dbbvwgi6and2fokqess5tojy2u	368	12	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	368	13	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	368	14	cut	cut	VBN
work_dbbvwgi6and2fokqess5tojy2u	368	15	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	368	16	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	368	17	freezing	freezing	JJ
work_dbbvwgi6and2fokqess5tojy2u	368	18	microtome	microtome	NN
work_dbbvwgi6and2fokqess5tojy2u	368	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	368	20	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	368	21	collected	collect	VBN
work_dbbvwgi6and2fokqess5tojy2u	368	22	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	368	23	PBS	PBS	NNP
work_dbbvwgi6and2fokqess5tojy2u	368	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	369	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	369	2	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	369	3	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	369	4	incubated	incubate	VBN
work_dbbvwgi6and2fokqess5tojy2u	369	5	overnight	overnight	RB
work_dbbvwgi6and2fokqess5tojy2u	369	6	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	369	7	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	369	8	polyclonal	polyclonal	JJ
work_dbbvwgi6and2fokqess5tojy2u	369	9	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	369	10	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	369	11	calbindin	calbindin	JJ
work_dbbvwgi6and2fokqess5tojy2u	369	12	D-28k	D-28k	NNP
work_dbbvwgi6and2fokqess5tojy2u	369	13	antibody	antibody	NN
work_dbbvwgi6and2fokqess5tojy2u	369	14	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	369	15	1:10,000	1:10,000	CD
work_dbbvwgi6and2fokqess5tojy2u	369	16	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	369	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	370	1	After	after	IN
work_dbbvwgi6and2fokqess5tojy2u	370	2	washing	washing	NN
work_dbbvwgi6and2fokqess5tojy2u	370	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	370	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	370	5	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	370	6	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	370	7	incubated	incubate	VBN
work_dbbvwgi6and2fokqess5tojy2u	370	8	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	370	9	one	one	CD
work_dbbvwgi6and2fokqess5tojy2u	370	10	hour	hour	NN
work_dbbvwgi6and2fokqess5tojy2u	370	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	370	12	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	370	13	biotinylated	biotinylated	JJ
work_dbbvwgi6and2fokqess5tojy2u	370	14	secondary	secondary	JJ
work_dbbvwgi6and2fokqess5tojy2u	370	15	antibody	antibody	NN
work_dbbvwgi6and2fokqess5tojy2u	370	16	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	370	17	1:500	1:500	CD
work_dbbvwgi6and2fokqess5tojy2u	370	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	370	19	followed	follow	VBN
work_dbbvwgi6and2fokqess5tojy2u	370	20	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	370	21	incubation	incubation	NN
work_dbbvwgi6and2fokqess5tojy2u	370	22	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	370	23	one	one	CD
work_dbbvwgi6and2fokqess5tojy2u	370	24	hour	hour	NN
work_dbbvwgi6and2fokqess5tojy2u	370	25	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	370	26	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	370	27	ABC	ABC	NNP
work_dbbvwgi6and2fokqess5tojy2u	370	28	elite	elite	NNP
work_dbbvwgi6and2fokqess5tojy2u	370	29	kit	kit	NN
work_dbbvwgi6and2fokqess5tojy2u	370	30	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	370	31	1:400	1:400	CD
work_dbbvwgi6and2fokqess5tojy2u	370	32	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	370	33	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	371	1	A	a	DT
work_dbbvwgi6and2fokqess5tojy2u	371	2	mixture	mixture	NN
work_dbbvwgi6and2fokqess5tojy2u	371	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	371	4	0.3	0.3	CD
work_dbbvwgi6and2fokqess5tojy2u	371	5	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	371	6	DAB-0.6	DAB-0.6	.
work_dbbvwgi6and2fokqess5tojy2u	371	7	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	371	8	nickel	nickel	NN
work_dbbvwgi6and2fokqess5tojy2u	371	9	sulfate-0.1	sulfate-0.1	NNP
work_dbbvwgi6and2fokqess5tojy2u	371	10	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	371	11	hydrogen	hydrogen	NN
work_dbbvwgi6and2fokqess5tojy2u	371	12	peroxide	peroxide	NN
work_dbbvwgi6and2fokqess5tojy2u	371	13	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	371	14	PBS	PBS	NNP
work_dbbvwgi6and2fokqess5tojy2u	371	15	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	371	16	used	use	VBN
work_dbbvwgi6and2fokqess5tojy2u	371	17	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	371	18	reveal	reveal	VB
work_dbbvwgi6and2fokqess5tojy2u	371	19	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	371	20	immunoreaction	immunoreaction	NN
work_dbbvwgi6and2fokqess5tojy2u	371	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	372	1	For	for	IN
work_dbbvwgi6and2fokqess5tojy2u	372	2	double	double	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	3	labeling	labeling	NN
work_dbbvwgi6and2fokqess5tojy2u	372	4	analyses	analysis	NNS
work_dbbvwgi6and2fokqess5tojy2u	372	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	372	6	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	372	7	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	372	8	incubated	incubate	VBN
work_dbbvwgi6and2fokqess5tojy2u	372	9	overnight	overnight	RB
work_dbbvwgi6and2fokqess5tojy2u	372	10	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	372	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	372	12	following	follow	VBG
work_dbbvwgi6and2fokqess5tojy2u	372	13	primary	primary	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	14	antibodies	antibody	NNS
work_dbbvwgi6and2fokqess5tojy2u	372	15	mixtures	mixture	NNS
work_dbbvwgi6and2fokqess5tojy2u	372	16	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	372	17	polyclonal	polyclonal	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	18	anti	anti	NNS
work_dbbvwgi6and2fokqess5tojy2u	372	19	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	20	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	21	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	372	22	1:400)/monoclonal	1:400)/monoclonal	CD
work_dbbvwgi6and2fokqess5tojy2u	372	23	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	24	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	25	calbindin	calbindin	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	26	D-28k	D-28k	NNP
work_dbbvwgi6and2fokqess5tojy2u	372	27	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	372	28	1:1000	1:1000	NNP
work_dbbvwgi6and2fokqess5tojy2u	372	29	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	372	30	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	372	31	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	372	32	polyclonal	polyclonal	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	33	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	34	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	35	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	36	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	372	37	1:400)/monoclonal	1:400)/monoclonal	CD
work_dbbvwgi6and2fokqess5tojy2u	372	38	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	39	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	40	p62	p62	JJ
work_dbbvwgi6and2fokqess5tojy2u	372	41	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	372	42	1:100	1:100	CD
work_dbbvwgi6and2fokqess5tojy2u	372	43	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	372	44	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	373	1	After	after	IN
work_dbbvwgi6and2fokqess5tojy2u	373	2	washing	washing	NN
work_dbbvwgi6and2fokqess5tojy2u	373	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	373	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	373	5	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	373	6	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	373	7	incubated	incubate	VBN
work_dbbvwgi6and2fokqess5tojy2u	373	8	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	373	9	one	one	CD
work_dbbvwgi6and2fokqess5tojy2u	373	10	hour	hour	NN
work_dbbvwgi6and2fokqess5tojy2u	373	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	373	12	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	373	13	mixture	mixture	NN
work_dbbvwgi6and2fokqess5tojy2u	373	14	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	373	15	Alexa	Alexa	NNP
work_dbbvwgi6and2fokqess5tojy2u	373	16	Fluor	Fluor	NNP
work_dbbvwgi6and2fokqess5tojy2u	373	17	®	®	NNP
work_dbbvwgi6and2fokqess5tojy2u	373	18	488	488	CD
work_dbbvwgi6and2fokqess5tojy2u	373	19	donkey	donkey	NN
work_dbbvwgi6and2fokqess5tojy2u	373	20	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	373	21	anti-	anti-	NN
work_dbbvwgi6and2fokqess5tojy2u	373	22	rabbit	rabbit	NN
work_dbbvwgi6and2fokqess5tojy2u	373	23	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	373	24	1:500	1:500	CD
work_dbbvwgi6and2fokqess5tojy2u	373	25	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	373	26	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	373	27	Alexa	Alexa	NNP
work_dbbvwgi6and2fokqess5tojy2u	373	28	Fluor	Fluor	NNP
work_dbbvwgi6and2fokqess5tojy2u	373	29	®	®	NNP
work_dbbvwgi6and2fokqess5tojy2u	373	30	594	594	CD
work_dbbvwgi6and2fokqess5tojy2u	373	31	donkey	donkey	NN
work_dbbvwgi6and2fokqess5tojy2u	373	32	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	373	33	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	373	34	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	373	35	mouse	mouse	JJ
work_dbbvwgi6and2fokqess5tojy2u	373	36	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	373	37	1:500	1:500	CD
work_dbbvwgi6and2fokqess5tojy2u	373	38	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	373	39	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	374	1	Images	image	NNS
work_dbbvwgi6and2fokqess5tojy2u	374	2	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	374	3	acquired	acquire	VBN
work_dbbvwgi6and2fokqess5tojy2u	374	4	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	374	5	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	374	6	Zeiss	Zeiss	NNP
work_dbbvwgi6and2fokqess5tojy2u	374	7	Axio	Axio	NNP
work_dbbvwgi6and2fokqess5tojy2u	374	8	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	374	9	Imager	Imager	NNP
work_dbbvwgi6and2fokqess5tojy2u	374	10	M1	M1	NNP
work_dbbvwgi6and2fokqess5tojy2u	374	11	microscope	microscope	NN
work_dbbvwgi6and2fokqess5tojy2u	374	12	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	375	1	Laser	Laser	NNP
work_dbbvwgi6and2fokqess5tojy2u	375	2	confocal	confocal	JJ
work_dbbvwgi6and2fokqess5tojy2u	375	3	analyses	analysis	NNS
work_dbbvwgi6and2fokqess5tojy2u	375	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	375	5	made	make	VBN
work_dbbvwgi6and2fokqess5tojy2u	375	6	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	375	7	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	375	8	Olympus	Olympus	NNP
work_dbbvwgi6and2fokqess5tojy2u	375	9	FluoView	FluoView	NNP
work_dbbvwgi6and2fokqess5tojy2u	375	10	1000	1000	CD
work_dbbvwgi6and2fokqess5tojy2u	375	11	upright	upright	JJ
work_dbbvwgi6and2fokqess5tojy2u	375	12	microscope	microscope	NN
work_dbbvwgi6and2fokqess5tojy2u	375	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	376	1	Electron	Electron	NNP
work_dbbvwgi6and2fokqess5tojy2u	376	2	microscopy	microscopy	JJ
work_dbbvwgi6and2fokqess5tojy2u	376	3	Two	Two	NNP
work_dbbvwgi6and2fokqess5tojy2u	376	4	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	376	5	nine	nine	CD
work_dbbvwgi6and2fokqess5tojy2u	376	6	month	month	NN
work_dbbvwgi6and2fokqess5tojy2u	376	7	old	old	JJ
work_dbbvwgi6and2fokqess5tojy2u	376	8	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	376	9	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	376	10	deeply	deeply	RB
work_dbbvwgi6and2fokqess5tojy2u	376	11	anaesthetized	anaesthetize	VBN
work_dbbvwgi6and2fokqess5tojy2u	376	12	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	376	13	pentobarbital	pentobarbital	NN
work_dbbvwgi6and2fokqess5tojy2u	376	14	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	376	15	80	80	CD
work_dbbvwgi6and2fokqess5tojy2u	376	16	mg	mg	NNP
work_dbbvwgi6and2fokqess5tojy2u	376	17	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	376	18	kg	kg	NNP
work_dbbvwgi6and2fokqess5tojy2u	376	19	i.p	i.p	NNP
work_dbbvwgi6and2fokqess5tojy2u	376	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	377	1	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	377	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	377	3	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	377	4	perfused	perfuse	VBD
work_dbbvwgi6and2fokqess5tojy2u	377	5	transcardially	transcardially	RB
work_dbbvwgi6and2fokqess5tojy2u	377	6	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	377	7	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	377	8	mixture	mixture	NN
work_dbbvwgi6and2fokqess5tojy2u	377	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	377	10	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	377	11	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	377	12	paraformaldehyde	paraformaldehyde	NN
work_dbbvwgi6and2fokqess5tojy2u	377	13	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	377	14	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	377	15	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	377	16	glutaraldehyde	glutaraldehyde	NN
work_dbbvwgi6and2fokqess5tojy2u	377	17	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	377	18	0,12	0,12	NNP
work_dbbvwgi6and2fokqess5tojy2u	377	19	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	377	20	phosphate	phosphate	NN
work_dbbvwgi6and2fokqess5tojy2u	377	21	buffer	buffer	NN
work_dbbvwgi6and2fokqess5tojy2u	377	22	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	377	23	PB	PB	NNP
work_dbbvwgi6and2fokqess5tojy2u	377	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	377	25	pH	pH	NNP
work_dbbvwgi6and2fokqess5tojy2u	377	26	7.2	7.2	CD
work_dbbvwgi6and2fokqess5tojy2u	377	27	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	377	28	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	378	1	Thereafter	thereafter	RB
work_dbbvwgi6and2fokqess5tojy2u	378	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	378	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	378	4	brains	brain	NNS
work_dbbvwgi6and2fokqess5tojy2u	378	5	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	378	6	dissected	dissect	VBN
work_dbbvwgi6and2fokqess5tojy2u	378	7	out	out	RP
work_dbbvwgi6and2fokqess5tojy2u	378	8	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	378	9	immersed	immerse	VBN
work_dbbvwgi6and2fokqess5tojy2u	378	10	overnight	overnight	RB
work_dbbvwgi6and2fokqess5tojy2u	378	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	378	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	378	13	same	same	JJ
work_dbbvwgi6and2fokqess5tojy2u	378	14	fixative	fixative	NN
work_dbbvwgi6and2fokqess5tojy2u	378	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	379	1	Sagittal	sagittal	JJ
work_dbbvwgi6and2fokqess5tojy2u	379	2	slices	slice	NNS
work_dbbvwgi6and2fokqess5tojy2u	379	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	379	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	379	5	cerebella	cerebella	NN
work_dbbvwgi6and2fokqess5tojy2u	379	6	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	379	7	cut	cut	VBN
work_dbbvwgi6and2fokqess5tojy2u	379	8	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	379	9	immersed	immerse	VBN
work_dbbvwgi6and2fokqess5tojy2u	379	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	379	11	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	379	12	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	379	13	OsO4	oso4	NN
work_dbbvwgi6and2fokqess5tojy2u	379	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	379	15	PB	PB	NNP
work_dbbvwgi6and2fokqess5tojy2u	379	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	379	17	stained	stain	VBN
work_dbbvwgi6and2fokqess5tojy2u	379	18	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	379	19	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	379	20	block	block	NN
work_dbbvwgi6and2fokqess5tojy2u	379	21	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	379	22	ethanolic	ethanolic	JJ
work_dbbvwgi6and2fokqess5tojy2u	379	23	0.5	0.5	CD
work_dbbvwgi6and2fokqess5tojy2u	379	24	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	379	25	uranyl	uranyl	NN
work_dbbvwgi6and2fokqess5tojy2u	379	26	acetate	acetate	JJ
work_dbbvwgi6and2fokqess5tojy2u	379	27	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	379	28	dehydrated	dehydrate	VBN
work_dbbvwgi6and2fokqess5tojy2u	379	29	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	379	30	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	379	31	increased	increase	VBN
work_dbbvwgi6and2fokqess5tojy2u	379	32	gradient	gradient	NN
work_dbbvwgi6and2fokqess5tojy2u	379	33	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	379	34	ethanol	ethanol	NN
work_dbbvwgi6and2fokqess5tojy2u	379	35	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	379	36	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	379	37	embedded	embed	VBN
work_dbbvwgi6and2fokqess5tojy2u	379	38	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	379	39	Durcupan	Durcupan	NNP
work_dbbvwgi6and2fokqess5tojy2u	379	40	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	379	41	Fluka	Fluka	NNP
work_dbbvwgi6and2fokqess5tojy2u	379	42	®	®	NNP
work_dbbvwgi6and2fokqess5tojy2u	379	43	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	379	44	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	380	1	Semithin	Semithin	NNP
work_dbbvwgi6and2fokqess5tojy2u	380	2	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	380	3	ultrathin	ultrathin	JJ
work_dbbvwgi6and2fokqess5tojy2u	380	4	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	380	5	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	380	6	obtained	obtain	VBN
work_dbbvwgi6and2fokqess5tojy2u	380	7	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	380	8	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	380	9	Leica	Leica	NNP
work_dbbvwgi6and2fokqess5tojy2u	380	10	EM	EM	NNP
work_dbbvwgi6and2fokqess5tojy2u	380	11	UC7	UC7	NNP
work_dbbvwgi6and2fokqess5tojy2u	380	12	ultramicrotome	ultramicrotome	NN
work_dbbvwgi6and2fokqess5tojy2u	380	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	381	1	Semithin	semithin	JJ
work_dbbvwgi6and2fokqess5tojy2u	381	2	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	381	3	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	381	4	stained	stain	VBN
work_dbbvwgi6and2fokqess5tojy2u	381	5	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	381	6	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	381	7	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	381	8	toluidine	toluidine	JJ
work_dbbvwgi6and2fokqess5tojy2u	381	9	blue	blue	NN
work_dbbvwgi6and2fokqess5tojy2u	381	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	382	1	Ultrathin	Ultrathin	NNP
work_dbbvwgi6and2fokqess5tojy2u	382	2	sections	section	NNS
work_dbbvwgi6and2fokqess5tojy2u	382	3	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	382	4	collected	collect	VBN
work_dbbvwgi6and2fokqess5tojy2u	382	5	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	382	6	copper	copper	NN
work_dbbvwgi6and2fokqess5tojy2u	382	7	grids	grid	NNS
work_dbbvwgi6and2fokqess5tojy2u	382	8	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	382	9	150	150	CD
work_dbbvwgi6and2fokqess5tojy2u	382	10	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	382	11	300	300	CD
work_dbbvwgi6and2fokqess5tojy2u	382	12	mesh	mesh	NN
work_dbbvwgi6and2fokqess5tojy2u	382	13	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	382	14	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	382	15	observed	observe	VBN
work_dbbvwgi6and2fokqess5tojy2u	382	16	without	without	IN
work_dbbvwgi6and2fokqess5tojy2u	382	17	counterstaining	counterstaine	VBG
work_dbbvwgi6and2fokqess5tojy2u	382	18	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	382	19	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	382	20	Zeiss	Zeiss	NNP
work_dbbvwgi6and2fokqess5tojy2u	382	21	Libra	Libra	NNP
work_dbbvwgi6and2fokqess5tojy2u	382	22	EM	EM	NNP
work_dbbvwgi6and2fokqess5tojy2u	382	23	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	382	24	80	80	CD
work_dbbvwgi6and2fokqess5tojy2u	382	25	kV	kV	NNP
work_dbbvwgi6and2fokqess5tojy2u	382	26	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	382	27	CITIUS	CITIUS	NNP
work_dbbvwgi6and2fokqess5tojy2u	382	28	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	382	29	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	383	1	behavioural	behavioural	JJ
work_dbbvwgi6and2fokqess5tojy2u	383	2	tests	test	NNS
work_dbbvwgi6and2fokqess5tojy2u	383	3	Anxiety	anxiety	NN
work_dbbvwgi6and2fokqess5tojy2u	383	4	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	383	5	evaluate	evaluate	VB
work_dbbvwgi6and2fokqess5tojy2u	383	6	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	383	7	anxiety	anxiety	NN
work_dbbvwgi6and2fokqess5tojy2u	383	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	383	9	two	two	CD
work_dbbvwgi6and2fokqess5tojy2u	383	10	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	383	11	protocols	protocol	NNS
work_dbbvwgi6and2fokqess5tojy2u	383	12	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	383	13	used	use	VBN
work_dbbvwgi6and2fokqess5tojy2u	383	14	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	383	15	59	59	CD
work_dbbvwgi6and2fokqess5tojy2u	383	16	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	383	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	384	1	Tail	tail	NN
work_dbbvwgi6and2fokqess5tojy2u	384	2	suspension	suspension	NN
work_dbbvwgi6and2fokqess5tojy2u	384	3	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	384	4	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	384	5	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	384	6	suspended	suspend	VBN
work_dbbvwgi6and2fokqess5tojy2u	384	7	above	above	IN
work_dbbvwgi6and2fokqess5tojy2u	384	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	384	9	floor	floor	NN
work_dbbvwgi6and2fokqess5tojy2u	384	10	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	384	11	fixing	fix	VBG
work_dbbvwgi6and2fokqess5tojy2u	384	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	384	13	end	end	NN
work_dbbvwgi6and2fokqess5tojy2u	384	14	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	384	15	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	384	16	tail	tail	NN
work_dbbvwgi6and2fokqess5tojy2u	384	17	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	384	18	wire	wire	VB
work_dbbvwgi6and2fokqess5tojy2u	384	19	netting	netting	JJ
work_dbbvwgi6and2fokqess5tojy2u	384	20	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	384	21	immobility	immobility	NN
work_dbbvwgi6and2fokqess5tojy2u	384	22	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	384	23	scored	score	VBN
work_dbbvwgi6and2fokqess5tojy2u	384	24	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	384	25	manual	manual	JJ
work_dbbvwgi6and2fokqess5tojy2u	384	26	observation	observation	NN
work_dbbvwgi6and2fokqess5tojy2u	384	27	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	384	28	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	384	29	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	384	30	min	min	NN
work_dbbvwgi6and2fokqess5tojy2u	384	31	test	test	NN
work_dbbvwgi6and2fokqess5tojy2u	384	32	session	session	NN
work_dbbvwgi6and2fokqess5tojy2u	384	33	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	385	1	Time	time	NN
work_dbbvwgi6and2fokqess5tojy2u	385	2	outside	outside	IN
work_dbbvwgi6and2fokqess5tojy2u	385	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	385	4	dark	dark	JJ
work_dbbvwgi6and2fokqess5tojy2u	385	5	box	box	NN
work_dbbvwgi6and2fokqess5tojy2u	385	6	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	385	7	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	385	8	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	385	9	placed	place	VBN
work_dbbvwgi6and2fokqess5tojy2u	385	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	385	11	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	385	12	rectangular	rectangular	JJ
work_dbbvwgi6and2fokqess5tojy2u	385	13	arena	arena	NN
work_dbbvwgi6and2fokqess5tojy2u	385	14	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	385	15	55x40x40	55x40x40	CD
work_dbbvwgi6and2fokqess5tojy2u	385	16	cm3	cm3	NNS
work_dbbvwgi6and2fokqess5tojy2u	385	17	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	385	18	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	385	19	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	385	20	dark	dark	JJ
work_dbbvwgi6and2fokqess5tojy2u	385	21	box	box	NN
work_dbbvwgi6and2fokqess5tojy2u	385	22	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	385	23	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	385	24	door	door	NN
work_dbbvwgi6and2fokqess5tojy2u	385	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	386	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	386	2	time	time	NN
work_dbbvwgi6and2fokqess5tojy2u	386	3	inside	inside	IN
work_dbbvwgi6and2fokqess5tojy2u	386	4	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	386	5	outside	outside	IN
work_dbbvwgi6and2fokqess5tojy2u	386	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	386	7	box	box	NN
work_dbbvwgi6and2fokqess5tojy2u	386	8	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	386	9	scored	score	VBN
work_dbbvwgi6and2fokqess5tojy2u	386	10	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	386	11	manual	manual	JJ
work_dbbvwgi6and2fokqess5tojy2u	386	12	observation	observation	NN
work_dbbvwgi6and2fokqess5tojy2u	386	13	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	386	14	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	386	15	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	386	16	min	min	NN
work_dbbvwgi6and2fokqess5tojy2u	386	17	test	test	NN
work_dbbvwgi6and2fokqess5tojy2u	386	18	session	session	NN
work_dbbvwgi6and2fokqess5tojy2u	386	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	387	1	Oncotarget56102www.impactjournals.com/oncotarget	Oncotarget56102www.impactjournals.com/oncotarget	``
work_dbbvwgi6and2fokqess5tojy2u	387	2	Learning	learning	NN
work_dbbvwgi6and2fokqess5tojy2u	387	3	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	387	4	memory	memory	NN
work_dbbvwgi6and2fokqess5tojy2u	387	5	Object	object	NN
work_dbbvwgi6and2fokqess5tojy2u	387	6	recognition	recognition	NN
work_dbbvwgi6and2fokqess5tojy2u	387	7	memory	memory	NN
work_dbbvwgi6and2fokqess5tojy2u	387	8	Mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	387	9	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	387	10	tested	test	VBN
work_dbbvwgi6and2fokqess5tojy2u	387	11	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	387	12	described	describe	VBN
work_dbbvwgi6and2fokqess5tojy2u	387	13	previously	previously	RB
work_dbbvwgi6and2fokqess5tojy2u	387	14	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	387	15	60	60	CD
work_dbbvwgi6and2fokqess5tojy2u	387	16	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	387	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	388	1	Briefly	briefly	RB
work_dbbvwgi6and2fokqess5tojy2u	388	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	388	3	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	388	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	388	5	placed	place	VBN
work_dbbvwgi6and2fokqess5tojy2u	388	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	388	7	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	388	8	rectangular	rectangular	JJ
work_dbbvwgi6and2fokqess5tojy2u	388	9	arena	arena	NN
work_dbbvwgi6and2fokqess5tojy2u	388	10	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	388	11	55x40x40	55x40x40	CD
work_dbbvwgi6and2fokqess5tojy2u	388	12	cm3	cm3	NNS
work_dbbvwgi6and2fokqess5tojy2u	388	13	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	388	14	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	388	15	two	two	CD
work_dbbvwgi6and2fokqess5tojy2u	388	16	identical	identical	JJ
work_dbbvwgi6and2fokqess5tojy2u	388	17	objects	object	NNS
work_dbbvwgi6and2fokqess5tojy2u	388	18	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	388	19	placed	place	VBN
work_dbbvwgi6and2fokqess5tojy2u	388	20	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	388	21	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	388	22	arena	arena	NN
work_dbbvwgi6and2fokqess5tojy2u	388	23	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	388	24	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	388	25	training	training	NN
work_dbbvwgi6and2fokqess5tojy2u	388	26	phase	phase	NN
work_dbbvwgi6and2fokqess5tojy2u	388	27	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	389	1	Subsequently	subsequently	RB
work_dbbvwgi6and2fokqess5tojy2u	389	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	389	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	389	4	animal	animal	NN
work_dbbvwgi6and2fokqess5tojy2u	389	5	’s	’s	POS
work_dbbvwgi6and2fokqess5tojy2u	389	6	memory	memory	NN
work_dbbvwgi6and2fokqess5tojy2u	389	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	389	8	one	one	CD
work_dbbvwgi6and2fokqess5tojy2u	389	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	389	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	389	11	original	original	JJ
work_dbbvwgi6and2fokqess5tojy2u	389	12	objects	object	NNS
work_dbbvwgi6and2fokqess5tojy2u	389	13	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	389	14	assessed	assess	VBN
work_dbbvwgi6and2fokqess5tojy2u	389	15	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	389	16	comparing	compare	VBG
work_dbbvwgi6and2fokqess5tojy2u	389	17	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	389	18	amount	amount	NN
work_dbbvwgi6and2fokqess5tojy2u	389	19	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	389	20	time	time	NN
work_dbbvwgi6and2fokqess5tojy2u	389	21	spent	spend	VBN
work_dbbvwgi6and2fokqess5tojy2u	389	22	exploring	explore	VBG
work_dbbvwgi6and2fokqess5tojy2u	389	23	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	389	24	novel	novel	JJ
work_dbbvwgi6and2fokqess5tojy2u	389	25	object	object	NN
work_dbbvwgi6and2fokqess5tojy2u	389	26	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	389	27	compared	compare	VBN
work_dbbvwgi6and2fokqess5tojy2u	389	28	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	389	29	that	that	DT
work_dbbvwgi6and2fokqess5tojy2u	389	30	spent	spend	VBN
work_dbbvwgi6and2fokqess5tojy2u	389	31	exploring	explore	VBG
work_dbbvwgi6and2fokqess5tojy2u	389	32	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	389	33	familiar	familiar	JJ
work_dbbvwgi6and2fokqess5tojy2u	389	34	one	one	CD
work_dbbvwgi6and2fokqess5tojy2u	389	35	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	390	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	390	2	relative	relative	JJ
work_dbbvwgi6and2fokqess5tojy2u	390	3	exploration	exploration	NN
work_dbbvwgi6and2fokqess5tojy2u	390	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	390	5	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	390	6	novel	novel	JJ
work_dbbvwgi6and2fokqess5tojy2u	390	7	object	object	NN
work_dbbvwgi6and2fokqess5tojy2u	390	8	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	390	9	expressed	express	VBN
work_dbbvwgi6and2fokqess5tojy2u	390	10	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	390	11	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	390	12	discrimination	discrimination	NN
work_dbbvwgi6and2fokqess5tojy2u	390	13	index	index	NN
work_dbbvwgi6and2fokqess5tojy2u	390	14	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	390	15	DI	DI	NNP
work_dbbvwgi6and2fokqess5tojy2u	390	16	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	390	17	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	390	18	tnovel	tnovel	NNP
work_dbbvwgi6and2fokqess5tojy2u	390	19	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	390	20	tfamiliar)/	tfamiliar)/	NNP
work_dbbvwgi6and2fokqess5tojy2u	390	21	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	390	22	tnovel	tnovel	NNP
work_dbbvwgi6and2fokqess5tojy2u	390	23	+	+	SYM
work_dbbvwgi6and2fokqess5tojy2u	390	24	tfamiliar	tfamiliar	NN
work_dbbvwgi6and2fokqess5tojy2u	390	25	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	390	26	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	390	27	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	391	1	step	step	NN
work_dbbvwgi6and2fokqess5tojy2u	391	2	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	391	3	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	391	4	passive	passive	JJ
work_dbbvwgi6and2fokqess5tojy2u	391	5	avoidance	avoidance	NN
work_dbbvwgi6and2fokqess5tojy2u	391	6	test	test	NN
work_dbbvwgi6and2fokqess5tojy2u	391	7	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	391	8	test	test	NN
work_dbbvwgi6and2fokqess5tojy2u	391	9	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	391	10	performed	perform	VBN
work_dbbvwgi6and2fokqess5tojy2u	391	11	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	391	12	described	describe	VBN
work_dbbvwgi6and2fokqess5tojy2u	391	13	previously	previously	RB
work_dbbvwgi6and2fokqess5tojy2u	391	14	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	391	15	60	60	CD
work_dbbvwgi6and2fokqess5tojy2u	391	16	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	391	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	392	1	Briefly	briefly	RB
work_dbbvwgi6and2fokqess5tojy2u	392	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	392	3	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	392	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	392	5	habituation	habituation	NN
work_dbbvwgi6and2fokqess5tojy2u	392	6	phase	phase	NN
work_dbbvwgi6and2fokqess5tojy2u	392	7	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	392	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	392	9	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	392	10	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	392	11	handled	handle	VBN
work_dbbvwgi6and2fokqess5tojy2u	392	12	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	392	13	allowed	allow	VBN
work_dbbvwgi6and2fokqess5tojy2u	392	14	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	392	15	move	move	VB
work_dbbvwgi6and2fokqess5tojy2u	392	16	freely	freely	RB
work_dbbvwgi6and2fokqess5tojy2u	392	17	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	392	18	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	392	19	min	min	NN
work_dbbvwgi6and2fokqess5tojy2u	392	20	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	392	21	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	392	22	chamber	chamber	NN
work_dbbvwgi6and2fokqess5tojy2u	392	23	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	392	24	47x18x26	47x18x26	CD
work_dbbvwgi6and2fokqess5tojy2u	392	25	cm3	cm3	NNS
work_dbbvwgi6and2fokqess5tojy2u	392	26	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	392	27	manufactured	manufacture	VBN
work_dbbvwgi6and2fokqess5tojy2u	392	28	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	392	29	Ugo	Ugo	NNP
work_dbbvwgi6and2fokqess5tojy2u	392	30	Basile	Basile	NNP
work_dbbvwgi6and2fokqess5tojy2u	392	31	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	392	32	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	393	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	393	2	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	393	3	training	training	NN
work_dbbvwgi6and2fokqess5tojy2u	393	4	phase	phase	NN
work_dbbvwgi6and2fokqess5tojy2u	393	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	393	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	393	7	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	393	8	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	393	9	confined	confine	VBN
work_dbbvwgi6and2fokqess5tojy2u	393	10	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	393	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	393	12	light	light	JJ
work_dbbvwgi6and2fokqess5tojy2u	393	13	compartment	compartment	NN
work_dbbvwgi6and2fokqess5tojy2u	393	14	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	393	15	then	then	RB
work_dbbvwgi6and2fokqess5tojy2u	393	16	30	30	CD
work_dbbvwgi6and2fokqess5tojy2u	393	17	s	s	NN
work_dbbvwgi6and2fokqess5tojy2u	393	18	later	later	RB
work_dbbvwgi6and2fokqess5tojy2u	393	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	393	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	393	21	door	door	NN
work_dbbvwgi6and2fokqess5tojy2u	393	22	separating	separate	VBG
work_dbbvwgi6and2fokqess5tojy2u	393	23	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	393	24	dark	dark	JJ
work_dbbvwgi6and2fokqess5tojy2u	393	25	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	393	26	light	light	NN
work_dbbvwgi6and2fokqess5tojy2u	393	27	compartments	compartment	NNS
work_dbbvwgi6and2fokqess5tojy2u	393	28	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	393	29	opened	open	VBN
work_dbbvwgi6and2fokqess5tojy2u	393	30	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	394	1	Once	once	IN
work_dbbvwgi6and2fokqess5tojy2u	394	2	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	394	3	entered	enter	VBD
work_dbbvwgi6and2fokqess5tojy2u	394	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	394	5	dark	dark	JJ
work_dbbvwgi6and2fokqess5tojy2u	394	6	compartment	compartment	NN
work_dbbvwgi6and2fokqess5tojy2u	394	7	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	394	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	394	9	door	door	NN
work_dbbvwgi6and2fokqess5tojy2u	394	10	closed	close	VBD
work_dbbvwgi6and2fokqess5tojy2u	394	11	automatically	automatically	RB
work_dbbvwgi6and2fokqess5tojy2u	394	12	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	394	13	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	394	14	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	394	15	received	receive	VBD
work_dbbvwgi6and2fokqess5tojy2u	394	16	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	394	17	electrical	electrical	JJ
work_dbbvwgi6and2fokqess5tojy2u	394	18	stimulation	stimulation	NN
work_dbbvwgi6and2fokqess5tojy2u	394	19	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	394	20	0.5	0.5	CD
work_dbbvwgi6and2fokqess5tojy2u	394	21	mA	mA	NNP
work_dbbvwgi6and2fokqess5tojy2u	394	22	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	394	23	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	394	24	s	s	NN
work_dbbvwgi6and2fokqess5tojy2u	394	25	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	394	26	delivered	deliver	VBD
work_dbbvwgi6and2fokqess5tojy2u	394	27	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	394	28	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	394	29	metal	metal	NN
work_dbbvwgi6and2fokqess5tojy2u	394	30	floor	floor	NN
work_dbbvwgi6and2fokqess5tojy2u	394	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	395	1	In	in	IN
work_dbbvwgi6and2fokqess5tojy2u	395	2	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	395	3	retention	retention	NN
work_dbbvwgi6and2fokqess5tojy2u	395	4	tests	test	NNS
work_dbbvwgi6and2fokqess5tojy2u	395	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	395	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	395	7	latency	latency	NN
work_dbbvwgi6and2fokqess5tojy2u	395	8	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	395	9	enter	enter	VB
work_dbbvwgi6and2fokqess5tojy2u	395	10	into	into	IN
work_dbbvwgi6and2fokqess5tojy2u	395	11	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	395	12	dark	dark	JJ
work_dbbvwgi6and2fokqess5tojy2u	395	13	compartment	compartment	NN
work_dbbvwgi6and2fokqess5tojy2u	395	14	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	395	15	escape	escape	VB
work_dbbvwgi6and2fokqess5tojy2u	395	16	latency	latency	NN
work_dbbvwgi6and2fokqess5tojy2u	395	17	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	395	18	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	395	19	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	395	20	measure	measure	NN
work_dbbvwgi6and2fokqess5tojy2u	395	21	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	395	22	information	information	NN
work_dbbvwgi6and2fokqess5tojy2u	395	23	learning	learning	NN
work_dbbvwgi6and2fokqess5tojy2u	395	24	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	395	25	memory	memory	NN
work_dbbvwgi6and2fokqess5tojy2u	395	26	retention	retention	NN
work_dbbvwgi6and2fokqess5tojy2u	395	27	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	396	1	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	396	2	compare	compare	VB
work_dbbvwgi6and2fokqess5tojy2u	396	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	396	4	results	result	NNS
work_dbbvwgi6and2fokqess5tojy2u	396	5	obtained	obtain	VBN
work_dbbvwgi6and2fokqess5tojy2u	396	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	396	7	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	396	8	experiments	experiment	NNS
work_dbbvwgi6and2fokqess5tojy2u	396	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	396	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	396	11	fold	fold	JJ
work_dbbvwgi6and2fokqess5tojy2u	396	12	change	change	NN
work_dbbvwgi6and2fokqess5tojy2u	396	13	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	396	14	escape	escape	NN
work_dbbvwgi6and2fokqess5tojy2u	396	15	latency	latency	NN
work_dbbvwgi6and2fokqess5tojy2u	396	16	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	396	17	respect	respect	NN
work_dbbvwgi6and2fokqess5tojy2u	396	18	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	396	19	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	396	20	latency	latency	NN
work_dbbvwgi6and2fokqess5tojy2u	396	21	obtained	obtain	VBN
work_dbbvwgi6and2fokqess5tojy2u	396	22	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	396	23	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	396	24	training	training	NN
work_dbbvwgi6and2fokqess5tojy2u	396	25	session	session	NN
work_dbbvwgi6and2fokqess5tojy2u	396	26	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	396	27	calculated	calculate	VBN
work_dbbvwgi6and2fokqess5tojy2u	396	28	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	397	1	Motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	397	2	function	function	NN
work_dbbvwgi6and2fokqess5tojy2u	397	3	Motor	Motor	NNP
work_dbbvwgi6and2fokqess5tojy2u	397	4	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	397	5	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	397	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	397	7	open	open	JJ
work_dbbvwgi6and2fokqess5tojy2u	397	8	field	field	NN
work_dbbvwgi6and2fokqess5tojy2u	397	9	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	397	10	evaluate	evaluate	VB
work_dbbvwgi6and2fokqess5tojy2u	397	11	locomotor	locomotor	NN
work_dbbvwgi6and2fokqess5tojy2u	397	12	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	397	13	exploratory	exploratory	JJ
work_dbbvwgi6and2fokqess5tojy2u	397	14	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	397	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	397	16	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	397	17	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	397	18	placed	place	VBN
work_dbbvwgi6and2fokqess5tojy2u	397	19	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	397	20	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	397	21	minutes	minute	NNS
work_dbbvwgi6and2fokqess5tojy2u	397	22	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	397	23	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	397	24	open	open	JJ
work_dbbvwgi6and2fokqess5tojy2u	397	25	field	field	NN
work_dbbvwgi6and2fokqess5tojy2u	397	26	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	397	27	38×21×15	38×21×15	NN
work_dbbvwgi6and2fokqess5tojy2u	397	28	cm	cm	NNS
work_dbbvwgi6and2fokqess5tojy2u	397	29	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	397	30	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	397	31	Cybertec	Cybertec	NNP
work_dbbvwgi6and2fokqess5tojy2u	397	32	S.A.	S.A.	NNP
work_dbbvwgi6and2fokqess5tojy2u	397	33	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	397	34	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	398	1	This	this	DT
work_dbbvwgi6and2fokqess5tojy2u	398	2	apparatus	apparatus	NN
work_dbbvwgi6and2fokqess5tojy2u	398	3	consisted	consist	VBD
work_dbbvwgi6and2fokqess5tojy2u	398	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	398	5	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	398	6	walled	walled	JJ
work_dbbvwgi6and2fokqess5tojy2u	398	7	platform	platform	NN
work_dbbvwgi6and2fokqess5tojy2u	398	8	containing	contain	VBG
work_dbbvwgi6and2fokqess5tojy2u	398	9	infrared	infrared	JJ
work_dbbvwgi6and2fokqess5tojy2u	398	10	emitters	emitter	NNS
work_dbbvwgi6and2fokqess5tojy2u	398	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	398	12	sensors	sensor	NNS
work_dbbvwgi6and2fokqess5tojy2u	398	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	398	14	IR	IR	NNP
work_dbbvwgi6and2fokqess5tojy2u	398	15	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	398	16	coupled	couple	VBD
work_dbbvwgi6and2fokqess5tojy2u	398	17	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	398	18	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	398	19	altimeter	altimeter	NN
work_dbbvwgi6and2fokqess5tojy2u	398	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	398	21	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	398	22	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	398	23	movement	movement	NN
work_dbbvwgi6and2fokqess5tojy2u	398	24	sensor	sensor	NN
work_dbbvwgi6and2fokqess5tojy2u	398	25	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	398	26	connected	connect	VBN
work_dbbvwgi6and2fokqess5tojy2u	398	27	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	398	28	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	398	29	computer	computer	NN
work_dbbvwgi6and2fokqess5tojy2u	398	30	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	398	31	recorded	record	VBD
work_dbbvwgi6and2fokqess5tojy2u	398	32	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	398	33	number	number	NN
work_dbbvwgi6and2fokqess5tojy2u	398	34	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	398	35	times	time	NNS
work_dbbvwgi6and2fokqess5tojy2u	398	36	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	398	37	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	398	38	interrupted	interrupt	VBD
work_dbbvwgi6and2fokqess5tojy2u	398	39	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	398	40	IR	IR	NNP
work_dbbvwgi6and2fokqess5tojy2u	398	41	beams	beam	NNS
work_dbbvwgi6and2fokqess5tojy2u	398	42	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	398	43	min	min	NN
work_dbbvwgi6and2fokqess5tojy2u	398	44	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	399	1	Fore	fore	NN
work_dbbvwgi6and2fokqess5tojy2u	399	2	limb	limb	NN
work_dbbvwgi6and2fokqess5tojy2u	399	3	grip	grip	NN
work_dbbvwgi6and2fokqess5tojy2u	399	4	strength	strength	NN
work_dbbvwgi6and2fokqess5tojy2u	399	5	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	399	6	evaluate	evaluate	VB
work_dbbvwgi6and2fokqess5tojy2u	399	7	fore	fore	JJ
work_dbbvwgi6and2fokqess5tojy2u	399	8	limb	limb	NN
work_dbbvwgi6and2fokqess5tojy2u	399	9	strength	strength	NN
work_dbbvwgi6and2fokqess5tojy2u	399	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	399	11	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	399	12	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	399	13	held	hold	VBN
work_dbbvwgi6and2fokqess5tojy2u	399	14	above	above	IN
work_dbbvwgi6and2fokqess5tojy2u	399	15	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	399	16	horizontal	horizontal	JJ
work_dbbvwgi6and2fokqess5tojy2u	399	17	wire	wire	NN
work_dbbvwgi6and2fokqess5tojy2u	399	18	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	399	19	lowered	lower	VBD
work_dbbvwgi6and2fokqess5tojy2u	399	20	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	399	21	allow	allow	VB
work_dbbvwgi6and2fokqess5tojy2u	399	22	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	399	23	fore	fore	NN
work_dbbvwgi6and2fokqess5tojy2u	399	24	limbs	limb	NNS
work_dbbvwgi6and2fokqess5tojy2u	399	25	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	399	26	grip	grip	VB
work_dbbvwgi6and2fokqess5tojy2u	399	27	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	399	28	wire	wire	NN
work_dbbvwgi6and2fokqess5tojy2u	399	29	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	400	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	400	2	ability	ability	NN
work_dbbvwgi6and2fokqess5tojy2u	400	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	400	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	400	5	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	400	6	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	400	7	remain	remain	VB
work_dbbvwgi6and2fokqess5tojy2u	400	8	attached	attach	VBN
work_dbbvwgi6and2fokqess5tojy2u	400	9	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	400	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	400	11	fore	fore	NNP
work_dbbvwgi6and2fokqess5tojy2u	400	12	limbs	limbs	NNP
work_dbbvwgi6and2fokqess5tojy2u	400	13	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	400	14	scored	score	VBN
work_dbbvwgi6and2fokqess5tojy2u	400	15	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	400	16	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	400	17	s.	s.	NN
work_dbbvwgi6and2fokqess5tojy2u	400	18	rotarod	rotarod	NNS
work_dbbvwgi6and2fokqess5tojy2u	400	19	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	400	20	habituate	habituate	VB
work_dbbvwgi6and2fokqess5tojy2u	400	21	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	400	22	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	400	23	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	400	24	rotarod	rotarod	NNS
work_dbbvwgi6and2fokqess5tojy2u	400	25	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	400	26	Ugo	Ugo	NNP
work_dbbvwgi6and2fokqess5tojy2u	400	27	Basile	Basile	NNP
work_dbbvwgi6and2fokqess5tojy2u	400	28	Biological	Biological	NNP
work_dbbvwgi6and2fokqess5tojy2u	400	29	Research	Research	NNP
work_dbbvwgi6and2fokqess5tojy2u	400	30	Apparatus	Apparatus	NNP
work_dbbvwgi6and2fokqess5tojy2u	400	31	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	400	32	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	400	33	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	400	34	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	400	35	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	400	36	placed	place	VBN
work_dbbvwgi6and2fokqess5tojy2u	400	37	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	400	38	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	400	39	roller	roller	NN
work_dbbvwgi6and2fokqess5tojy2u	400	40	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	400	41	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	400	42	speed	speed	NN
work_dbbvwgi6and2fokqess5tojy2u	400	43	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	400	44	20	20	CD
work_dbbvwgi6and2fokqess5tojy2u	400	45	rpm	rpm	NN
work_dbbvwgi6and2fokqess5tojy2u	400	46	until	until	IN
work_dbbvwgi6and2fokqess5tojy2u	400	47	they	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	400	48	could	could	MD
work_dbbvwgi6and2fokqess5tojy2u	400	49	remain	remain	VB
work_dbbvwgi6and2fokqess5tojy2u	400	50	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	400	51	it	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	400	52	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	400	53	one	one	CD
work_dbbvwgi6and2fokqess5tojy2u	400	54	minute	minute	NN
work_dbbvwgi6and2fokqess5tojy2u	400	55	without	without	IN
work_dbbvwgi6and2fokqess5tojy2u	400	56	falling	fall	VBG
work_dbbvwgi6and2fokqess5tojy2u	400	57	off	off	RP
work_dbbvwgi6and2fokqess5tojy2u	400	58	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	401	1	To	to	TO
work_dbbvwgi6and2fokqess5tojy2u	401	2	assay	assay	NNP
work_dbbvwgi6and2fokqess5tojy2u	401	3	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	401	4	coordination	coordination	NN
work_dbbvwgi6and2fokqess5tojy2u	401	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	401	6	animals	animal	NNS
work_dbbvwgi6and2fokqess5tojy2u	401	7	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	401	8	then	then	RB
work_dbbvwgi6and2fokqess5tojy2u	401	9	tested	test	VBN
work_dbbvwgi6and2fokqess5tojy2u	401	10	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	401	11	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	401	12	rotational	rotational	JJ
work_dbbvwgi6and2fokqess5tojy2u	401	13	speed	speed	NN
work_dbbvwgi6and2fokqess5tojy2u	401	14	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	401	15	20	20	CD
work_dbbvwgi6and2fokqess5tojy2u	401	16	rpm	rpm	NN
work_dbbvwgi6and2fokqess5tojy2u	401	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	401	18	accelerating	accelerate	VBG
work_dbbvwgi6and2fokqess5tojy2u	401	19	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	401	20	60	60	CD
work_dbbvwgi6and2fokqess5tojy2u	401	21	rpm	rpm	NN
work_dbbvwgi6and2fokqess5tojy2u	401	22	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	401	23	increments	increment	NNS
work_dbbvwgi6and2fokqess5tojy2u	401	24	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	401	25	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	401	26	rpm	rpm	NN
work_dbbvwgi6and2fokqess5tojy2u	401	27	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	401	28	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	401	29	quantifying	quantify	VBG
work_dbbvwgi6and2fokqess5tojy2u	401	30	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	401	31	number	number	NN
work_dbbvwgi6and2fokqess5tojy2u	401	32	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	401	33	falls	fall	NNS
work_dbbvwgi6and2fokqess5tojy2u	401	34	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	401	35	each	each	DT
work_dbbvwgi6and2fokqess5tojy2u	401	36	increase	increase	NN
work_dbbvwgi6and2fokqess5tojy2u	401	37	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	401	38	speed	speed	NN
work_dbbvwgi6and2fokqess5tojy2u	401	39	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	402	1	Electrophysiological	electrophysiological	JJ
work_dbbvwgi6and2fokqess5tojy2u	402	2	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	402	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	402	4	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	402	5	medial	medial	JJ
work_dbbvwgi6and2fokqess5tojy2u	402	6	gastrocnemius	gastrocnemius	NN
work_dbbvwgi6and2fokqess5tojy2u	402	7	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	402	8	MG	MG	NNP
work_dbbvwgi6and2fokqess5tojy2u	402	9	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	402	10	muscle	muscle	NN
work_dbbvwgi6and2fokqess5tojy2u	402	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	402	12	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	402	13	Compound	Compound	NNP
work_dbbvwgi6and2fokqess5tojy2u	402	14	muscular	muscular	JJ
work_dbbvwgi6and2fokqess5tojy2u	402	15	action	action	NN
work_dbbvwgi6and2fokqess5tojy2u	402	16	potentials	potential	NNS
work_dbbvwgi6and2fokqess5tojy2u	402	17	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	402	18	CMAPs	CMAPs	NNPS
work_dbbvwgi6and2fokqess5tojy2u	402	19	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	402	20	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	402	21	recorded	record	VBN
work_dbbvwgi6and2fokqess5tojy2u	402	22	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	402	23	anesthetized	anesthetize	VBN
work_dbbvwgi6and2fokqess5tojy2u	402	24	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	402	25	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	402	26	tribromethanol	tribromethanol	NN
work_dbbvwgi6and2fokqess5tojy2u	402	27	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	402	28	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	402	29	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	402	30	0.15	0.15	CD
work_dbbvwgi6and2fokqess5tojy2u	402	31	ml/10	ml/10	NNP
work_dbbvwgi6and2fokqess5tojy2u	402	32	g	g	NN
work_dbbvwgi6and2fokqess5tojy2u	402	33	body	body	NN
work_dbbvwgi6and2fokqess5tojy2u	402	34	weight	weight	NNP
work_dbbvwgi6and2fokqess5tojy2u	402	35	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	402	36	i.p	i.p	NNP
work_dbbvwgi6and2fokqess5tojy2u	402	37	.	.	NNP
work_dbbvwgi6and2fokqess5tojy2u	402	38	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	403	1	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	403	2	described	describe	VBN
work_dbbvwgi6and2fokqess5tojy2u	403	3	previously	previously	RB
work_dbbvwgi6and2fokqess5tojy2u	403	4	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	403	5	46,61	46,61	CD
work_dbbvwgi6and2fokqess5tojy2u	403	6	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	403	7	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	404	1	Briefly	briefly	RB
work_dbbvwgi6and2fokqess5tojy2u	404	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	404	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	404	4	recording	recording	NN
work_dbbvwgi6and2fokqess5tojy2u	404	5	needle	needle	NN
work_dbbvwgi6and2fokqess5tojy2u	404	6	electrode	electrode	NNP
work_dbbvwgi6and2fokqess5tojy2u	404	7	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	404	8	placed	place	VBN
work_dbbvwgi6and2fokqess5tojy2u	404	9	into	into	IN
work_dbbvwgi6and2fokqess5tojy2u	404	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	404	11	medial	medial	JJ
work_dbbvwgi6and2fokqess5tojy2u	404	12	part	part	NN
work_dbbvwgi6and2fokqess5tojy2u	404	13	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	404	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	404	15	MG	MG	NNP
work_dbbvwgi6and2fokqess5tojy2u	404	16	muscle	muscle	NN
work_dbbvwgi6and2fokqess5tojy2u	404	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	404	18	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	404	19	reference	reference	NN
work_dbbvwgi6and2fokqess5tojy2u	404	20	electrode	electrode	NN
work_dbbvwgi6and2fokqess5tojy2u	404	21	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	404	22	situated	situate	VBN
work_dbbvwgi6and2fokqess5tojy2u	404	23	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	404	24	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	404	25	base	base	NN
work_dbbvwgi6and2fokqess5tojy2u	404	26	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	404	27	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	404	28	fifth	fifth	JJ
work_dbbvwgi6and2fokqess5tojy2u	404	29	phalanx	phalanx	NN
work_dbbvwgi6and2fokqess5tojy2u	404	30	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	405	1	A	a	DT
work_dbbvwgi6and2fokqess5tojy2u	405	2	ground	ground	NN
work_dbbvwgi6and2fokqess5tojy2u	405	3	electrode	electrode	NN
work_dbbvwgi6and2fokqess5tojy2u	405	4	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	405	5	placed	place	VBN
work_dbbvwgi6and2fokqess5tojy2u	405	6	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	405	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	405	8	base	base	NN
work_dbbvwgi6and2fokqess5tojy2u	405	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	405	10	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	405	11	tail	tail	NN
work_dbbvwgi6and2fokqess5tojy2u	405	12	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	406	1	Stimulating	stimulate	VBG
work_dbbvwgi6and2fokqess5tojy2u	406	2	needle	needle	NN
work_dbbvwgi6and2fokqess5tojy2u	406	3	electrodes	electrode	NNS
work_dbbvwgi6and2fokqess5tojy2u	406	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	406	5	placed	place	VBN
work_dbbvwgi6and2fokqess5tojy2u	406	6	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	406	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	406	8	sciatic	sciatic	JJ
work_dbbvwgi6and2fokqess5tojy2u	406	9	notch	notch	NN
work_dbbvwgi6and2fokqess5tojy2u	406	10	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	406	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	406	12	head	head	NN
work_dbbvwgi6and2fokqess5tojy2u	406	13	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	406	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	406	15	fibula	fibula	NN
work_dbbvwgi6and2fokqess5tojy2u	406	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	407	1	Stimulation	stimulation	NN
work_dbbvwgi6and2fokqess5tojy2u	407	2	protocols	protocol	NNS
work_dbbvwgi6and2fokqess5tojy2u	407	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	407	4	supramaximal	supramaximal	JJ
work_dbbvwgi6and2fokqess5tojy2u	407	5	current	current	JJ
work_dbbvwgi6and2fokqess5tojy2u	407	6	pulses	pulse	NNS
work_dbbvwgi6and2fokqess5tojy2u	407	7	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	407	8	0.05	0.05	CD
work_dbbvwgi6and2fokqess5tojy2u	407	9	ms	ms	NNP
work_dbbvwgi6and2fokqess5tojy2u	407	10	duration	duration	NN
work_dbbvwgi6and2fokqess5tojy2u	407	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	407	12	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	407	13	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	407	14	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	407	15	mA	mA	NNP
work_dbbvwgi6and2fokqess5tojy2u	407	16	amplitude	amplitude	NN
work_dbbvwgi6and2fokqess5tojy2u	407	17	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	407	18	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	407	19	applied	apply	VBN
work_dbbvwgi6and2fokqess5tojy2u	407	20	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	407	21	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	407	22	short	short	JJ
work_dbbvwgi6and2fokqess5tojy2u	407	23	train	train	NN
work_dbbvwgi6and2fokqess5tojy2u	407	24	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	407	25	100	100	CD
work_dbbvwgi6and2fokqess5tojy2u	407	26	Hz	Hz	NNP
work_dbbvwgi6and2fokqess5tojy2u	407	27	pulses	pulse	NNS
work_dbbvwgi6and2fokqess5tojy2u	407	28	generated	generate	VBN
work_dbbvwgi6and2fokqess5tojy2u	407	29	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	407	30	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	407	31	isolated	isolate	VBN
work_dbbvwgi6and2fokqess5tojy2u	407	32	pulse	pulse	NN
work_dbbvwgi6and2fokqess5tojy2u	407	33	stimulator	stimulator	NN
work_dbbvwgi6and2fokqess5tojy2u	407	34	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	407	35	Pulse	Pulse	NNP
work_dbbvwgi6and2fokqess5tojy2u	407	36	Train	Train	NNP
work_dbbvwgi6and2fokqess5tojy2u	407	37	Stimulator	Stimulator	NNP
work_dbbvwgi6and2fokqess5tojy2u	407	38	Cibertec	Cibertec	NNP
work_dbbvwgi6and2fokqess5tojy2u	407	39	cs-20	cs-20	NNP
work_dbbvwgi6and2fokqess5tojy2u	407	40	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	407	41	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	408	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	408	2	outputs	output	NNS
work_dbbvwgi6and2fokqess5tojy2u	408	3	recorded	record	VBN
work_dbbvwgi6and2fokqess5tojy2u	408	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	408	5	differentially	differentially	RB
work_dbbvwgi6and2fokqess5tojy2u	408	6	amplified	amplify	VBN
work_dbbvwgi6and2fokqess5tojy2u	408	7	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	408	8	P511	P511	NNP
work_dbbvwgi6and2fokqess5tojy2u	408	9	AC	AC	NNP
work_dbbvwgi6and2fokqess5tojy2u	408	10	Amplifier	Amplifier	NNP
work_dbbvwgi6and2fokqess5tojy2u	408	11	Astro	Astro	NNP
work_dbbvwgi6and2fokqess5tojy2u	408	12	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	408	13	Med	Med	NNP
work_dbbvwgi6and2fokqess5tojy2u	408	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	408	15	INC	INC	NNP
work_dbbvwgi6and2fokqess5tojy2u	408	16	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	408	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	408	18	digitally	digitally	RB
work_dbbvwgi6and2fokqess5tojy2u	408	19	acquired	acquire	VBD
work_dbbvwgi6and2fokqess5tojy2u	408	20	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	408	21	10,000	10,000	CD
work_dbbvwgi6and2fokqess5tojy2u	408	22	samples	sample	NNS
work_dbbvwgi6and2fokqess5tojy2u	408	23	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	408	24	s	s	NNP
work_dbbvwgi6and2fokqess5tojy2u	408	25	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	408	26	CED	CED	NNP
work_dbbvwgi6and2fokqess5tojy2u	408	27	1401	1401	CD
work_dbbvwgi6and2fokqess5tojy2u	408	28	Plus	plus	CC
work_dbbvwgi6and2fokqess5tojy2u	408	29	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	408	30	Cambridge	Cambridge	NNP
work_dbbvwgi6and2fokqess5tojy2u	408	31	Electronic	Electronic	NNP
work_dbbvwgi6and2fokqess5tojy2u	408	32	Designed	Designed	NNP
work_dbbvwgi6and2fokqess5tojy2u	408	33	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	408	34	Cambridge	Cambridge	NNP
work_dbbvwgi6and2fokqess5tojy2u	408	35	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	408	36	UK	UK	NNP
work_dbbvwgi6and2fokqess5tojy2u	408	37	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	408	38	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	408	39	stored	store	VBN
work_dbbvwgi6and2fokqess5tojy2u	408	40	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	408	41	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	408	42	computer	computer	NN
work_dbbvwgi6and2fokqess5tojy2u	408	43	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	408	44	later	later	JJ
work_dbbvwgi6and2fokqess5tojy2u	408	45	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	408	46	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	409	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	409	2	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	409	3	consisted	consist	VBD
work_dbbvwgi6and2fokqess5tojy2u	409	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	409	5	measuring	measure	VBG
work_dbbvwgi6and2fokqess5tojy2u	409	6	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	409	7	amplitude	amplitude	NN
work_dbbvwgi6and2fokqess5tojy2u	409	8	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	409	9	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	409	10	positive	positive	JJ
work_dbbvwgi6and2fokqess5tojy2u	409	11	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	409	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	409	13	negative	negative	JJ
work_dbbvwgi6and2fokqess5tojy2u	409	14	peak	peak	NN
work_dbbvwgi6and2fokqess5tojy2u	409	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	409	16	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	409	17	CMAPs	CMAPs	NNPS
work_dbbvwgi6and2fokqess5tojy2u	409	18	recorded	record	VBN
work_dbbvwgi6and2fokqess5tojy2u	409	19	during	during	IN
work_dbbvwgi6and2fokqess5tojy2u	409	20	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	409	21	train	train	NN
work_dbbvwgi6and2fokqess5tojy2u	409	22	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	409	23	stimuli	stimulus	NNS
work_dbbvwgi6and2fokqess5tojy2u	409	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	409	25	normalizing	normalize	VBG
work_dbbvwgi6and2fokqess5tojy2u	409	26	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	409	27	amplitude	amplitude	NN
work_dbbvwgi6and2fokqess5tojy2u	409	28	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	409	29	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	409	30	first	first	JJ
work_dbbvwgi6and2fokqess5tojy2u	409	31	response	response	NN
work_dbbvwgi6and2fokqess5tojy2u	409	32	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	410	1	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	410	2	culture	culture	NN
work_dbbvwgi6and2fokqess5tojy2u	410	3	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	410	4	transfection	transfection	NN
work_dbbvwgi6and2fokqess5tojy2u	410	5	Human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	410	6	fibroblasts	fibroblast	NNS
work_dbbvwgi6and2fokqess5tojy2u	410	7	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	410	8	ethical	ethical	JJ
work_dbbvwgi6and2fokqess5tojy2u	410	9	statements	statement	NNS
work_dbbvwgi6and2fokqess5tojy2u	410	10	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	410	11	previously	previously	RB
work_dbbvwgi6and2fokqess5tojy2u	410	12	described	describe	VBN
work_dbbvwgi6and2fokqess5tojy2u	410	13	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	410	14	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	410	15	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	410	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	411	1	U2OS	U2OS	NNP
work_dbbvwgi6and2fokqess5tojy2u	411	2	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	411	3	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	411	4	obtained	obtain	VBN
work_dbbvwgi6and2fokqess5tojy2u	411	5	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	411	6	ATCC	ATCC	NNP
work_dbbvwgi6and2fokqess5tojy2u	411	7	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	412	1	Cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	412	2	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	412	3	cultured	culture	VBN
work_dbbvwgi6and2fokqess5tojy2u	412	4	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	412	5	37	37	CD
work_dbbvwgi6and2fokqess5tojy2u	412	6	°	°	NNS
work_dbbvwgi6and2fokqess5tojy2u	412	7	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	412	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	412	9	Dulbecco	Dulbecco	NNP
work_dbbvwgi6and2fokqess5tojy2u	412	10	’s	’s	POS
work_dbbvwgi6and2fokqess5tojy2u	412	11	modified	modify	VBN
work_dbbvwgi6and2fokqess5tojy2u	412	12	Eagle	Eagle	NNP
work_dbbvwgi6and2fokqess5tojy2u	412	13	’s	’s	POS
work_dbbvwgi6and2fokqess5tojy2u	412	14	medium	medium	NN
work_dbbvwgi6and2fokqess5tojy2u	412	15	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	412	16	DMEM	DMEM	NNP
work_dbbvwgi6and2fokqess5tojy2u	412	17	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	412	18	supplemented	supplement	VBD
work_dbbvwgi6and2fokqess5tojy2u	412	19	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	412	20	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	412	21	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	412	22	fetal	fetal	JJ
work_dbbvwgi6and2fokqess5tojy2u	412	23	bovine	bovine	NN
work_dbbvwgi6and2fokqess5tojy2u	412	24	serum	serum	NN
work_dbbvwgi6and2fokqess5tojy2u	412	25	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	412	26	100	100	CD
work_dbbvwgi6and2fokqess5tojy2u	412	27	units	unit	NNS
work_dbbvwgi6and2fokqess5tojy2u	412	28	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	412	29	ml	ml	NNP
work_dbbvwgi6and2fokqess5tojy2u	412	30	penicillin	penicillin	NNP
work_dbbvwgi6and2fokqess5tojy2u	412	31	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	412	32	100	100	CD
work_dbbvwgi6and2fokqess5tojy2u	412	33	µg	µg	IN
work_dbbvwgi6and2fokqess5tojy2u	412	34	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	412	35	ml	ml	NNP
work_dbbvwgi6and2fokqess5tojy2u	412	36	streptomycin	streptomycin	NNP
work_dbbvwgi6and2fokqess5tojy2u	412	37	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	412	38	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	412	39	mM	mM	NNP
work_dbbvwgi6and2fokqess5tojy2u	412	40	glutamine	glutamine	NN
work_dbbvwgi6and2fokqess5tojy2u	412	41	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	413	1	Transfection	transfection	NN
work_dbbvwgi6and2fokqess5tojy2u	413	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	413	3	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	413	4	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	413	5	siRNAs	siRNAs	NNP
work_dbbvwgi6and2fokqess5tojy2u	413	6	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	413	7	Non	Non	NNP
work_dbbvwgi6and2fokqess5tojy2u	413	8	Targeting	Targeting	NNP
work_dbbvwgi6and2fokqess5tojy2u	413	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	413	10	NT	NT	NNP
work_dbbvwgi6and2fokqess5tojy2u	413	11	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	413	12	UAGCGACUAAACACAUCAA	UAGCGACUAAACACAUCAA	NNP
work_dbbvwgi6and2fokqess5tojy2u	413	13	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	413	14	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	413	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	413	16	H2	H2	NNP
work_dbbvwgi6and2fokqess5tojy2u	413	17	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	413	18	GACUGUAGCCAGAUUGAAA	GACUGUAGCCAGAUUGAAA	NNP
work_dbbvwgi6and2fokqess5tojy2u	413	19	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	413	20	purchased	purchase	VBD
work_dbbvwgi6and2fokqess5tojy2u	413	21	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	413	22	GenePharma	GenePharma	NNP
work_dbbvwgi6and2fokqess5tojy2u	413	23	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	413	24	carried	carry	VBN
work_dbbvwgi6and2fokqess5tojy2u	413	25	out	out	RP
work_dbbvwgi6and2fokqess5tojy2u	413	26	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	413	27	calcium	calcium	NN
work_dbbvwgi6and2fokqess5tojy2u	413	28	phosphate	phosphate	NN
work_dbbvwgi6and2fokqess5tojy2u	413	29	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	414	1	Transfected	transfecte	VBN
work_dbbvwgi6and2fokqess5tojy2u	414	2	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	414	3	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	414	4	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	414	5	72	72	CD
work_dbbvwgi6and2fokqess5tojy2u	414	6	hours	hour	NNS
work_dbbvwgi6and2fokqess5tojy2u	414	7	post	post	NN
work_dbbvwgi6and2fokqess5tojy2u	414	8	-	-	NN
work_dbbvwgi6and2fokqess5tojy2u	414	9	transfection	transfection	NN
work_dbbvwgi6and2fokqess5tojy2u	414	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	415	1	MG132	MG132	NNP
work_dbbvwgi6and2fokqess5tojy2u	415	2	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	415	3	Z	Z	NNP
work_dbbvwgi6and2fokqess5tojy2u	415	4	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	415	5	Leu	Leu	NNP
work_dbbvwgi6and2fokqess5tojy2u	415	6	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	415	7	Leu	Leu	NNP
work_dbbvwgi6and2fokqess5tojy2u	415	8	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	415	9	Leu	Leu	NNP
work_dbbvwgi6and2fokqess5tojy2u	415	10	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	415	11	al	al	NNP
work_dbbvwgi6and2fokqess5tojy2u	415	12	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	415	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	415	14	Sigma	Sigma	NNP
work_dbbvwgi6and2fokqess5tojy2u	415	15	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	415	16	Aldrich	Aldrich	NNP
work_dbbvwgi6and2fokqess5tojy2u	415	17	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	415	18	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	415	19	added	add	VBN
work_dbbvwgi6and2fokqess5tojy2u	415	20	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	415	21	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	415	22	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	415	23	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	415	24	6	6	CD
work_dbbvwgi6and2fokqess5tojy2u	415	25	hours	hour	NNS
work_dbbvwgi6and2fokqess5tojy2u	415	26	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	415	27	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	415	28	final	final	JJ
work_dbbvwgi6and2fokqess5tojy2u	415	29	concentration	concentration	NN
work_dbbvwgi6and2fokqess5tojy2u	415	30	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	415	31	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	415	32	µM.	µM.	NNS
work_dbbvwgi6and2fokqess5tojy2u	416	1	Antibodies	antibody	NNS
work_dbbvwgi6and2fokqess5tojy2u	416	2	used	use	VBD
work_dbbvwgi6and2fokqess5tojy2u	416	3	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	416	4	following	follow	VBG
work_dbbvwgi6and2fokqess5tojy2u	416	5	antibodies	antibody	NNS
work_dbbvwgi6and2fokqess5tojy2u	416	6	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	416	7	used	use	VBN
work_dbbvwgi6and2fokqess5tojy2u	416	8	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	416	9	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	10	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	11	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	12	monoclonal	monoclonal	NN
work_dbbvwgi6and2fokqess5tojy2u	416	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	14	BD	BD	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	15	Biosciences	Biosciences	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	16	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	17	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	416	18	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	19	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	20	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	21	polyclonal	polyclonal	NN
work_dbbvwgi6and2fokqess5tojy2u	416	22	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	23	32	32	CD
work_dbbvwgi6and2fokqess5tojy2u	416	24	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	25	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	416	26	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	27	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	28	p21	p21	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	29	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	30	C-19	c-19	CD
work_dbbvwgi6and2fokqess5tojy2u	416	31	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	32	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	416	33	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	34	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	35	p62	p62	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	36	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	37	SQSTM1	SQSTM1	NNS
work_dbbvwgi6and2fokqess5tojy2u	416	38	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	39	D-3	D-3	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	40	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	41	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	416	42	sc-	sc-	CD
work_dbbvwgi6and2fokqess5tojy2u	416	43	28359	28359	CD
work_dbbvwgi6and2fokqess5tojy2u	416	44	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	45	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	416	46	anti	anti	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	47	β	β	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	48	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	416	49	actin	actin	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	50	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	51	Santa	Santa	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	52	Cruz	Cruz	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	53	Biotechnology	Biotechnology	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	54	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	416	55	Inc.	Inc.	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	56	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	57	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	416	58	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	59	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	60	calbindin	calbindin	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	61	D-28k	D-28k	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	62	polyclonal	polyclonal	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	63	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	64	Cb-38a	Cb-38a	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	65	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	416	66	Swant	Swant	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	67	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	68	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	416	69	anti-	anti-	NN
work_dbbvwgi6and2fokqess5tojy2u	416	70	calbindin	calbindin	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	71	D-28k	D-28k	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	72	monoclonal	monoclonal	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	73	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	74	Cb-955	cb-955	XX
work_dbbvwgi6and2fokqess5tojy2u	416	75	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	416	76	Sigma	Sigma	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	77	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	78	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	416	79	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	80	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	81	p53	p53	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	82	Oncotarget56103www.impactjournals.com/oncotarget	Oncotarget56103www.impactjournals.com/oncotarget	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	83	Ab-5	Ab-5	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	84	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	85	DO-7	DO-7	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	86	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	87	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	88	Neo	Neo	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	89	Markers	Markers	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	90	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	91	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	416	92	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	93	-	-	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	94	USP33	usp33	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	95	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	96	Proteintech	Proteintech	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	97	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	98	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	416	99	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	100	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	101	Ran	ran	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	102	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	103	62	62	CD
work_dbbvwgi6and2fokqess5tojy2u	416	104	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	105	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	416	106	anti	anti	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	107	α	α	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	108	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	416	109	tubulin	tubulin	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	110	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	111	Ab-1	Ab-1	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	112	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	416	113	Calbiochem	Calbiochem	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	114	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	115	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	416	116	Alexa	Alexa	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	117	Fluor	Fluor	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	118	®	®	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	119	488	488	CD
work_dbbvwgi6and2fokqess5tojy2u	416	120	donkey	donkey	NN
work_dbbvwgi6and2fokqess5tojy2u	416	121	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	416	122	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	123	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	124	rabbit	rabbit	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	125	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	126	A21207	a21207	NN
work_dbbvwgi6and2fokqess5tojy2u	416	127	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	128	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	416	129	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	416	130	Alexa	Alexa	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	131	Fluor	Fluor	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	132	®	®	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	133	594	594	CD
work_dbbvwgi6and2fokqess5tojy2u	416	134	donkey	donkey	NN
work_dbbvwgi6and2fokqess5tojy2u	416	135	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	416	136	anti	anti	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	137	-	-	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	138	mouse	mouse	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	139	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	140	A21203	A21203	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	141	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	142	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	143	Invitrogen	Invitrogen	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	144	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	145	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	416	146	horseradish	horseradish	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	147	peroxidase	peroxidase	NN
work_dbbvwgi6and2fokqess5tojy2u	416	148	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	416	149	conjugated	conjugate	VBN
work_dbbvwgi6and2fokqess5tojy2u	416	150	secondary	secondary	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	151	antibodies	antibody	NNS
work_dbbvwgi6and2fokqess5tojy2u	416	152	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	153	Invitrogen	Invitrogen	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	154	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	155	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	416	156	biotin	biotin	NN
work_dbbvwgi6and2fokqess5tojy2u	416	157	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	416	158	conjugated	conjugate	VBN
work_dbbvwgi6and2fokqess5tojy2u	416	159	secondary	secondary	JJ
work_dbbvwgi6and2fokqess5tojy2u	416	160	antibodies	antibody	NNS
work_dbbvwgi6and2fokqess5tojy2u	416	161	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	162	Vector	Vector	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	163	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	164	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	416	165	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	416	166	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	416	167	Avidine	Avidine	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	168	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	416	169	Streptavidine	streptavidine	NN
work_dbbvwgi6and2fokqess5tojy2u	416	170	Elite	Elite	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	171	Kit	kit	NN
work_dbbvwgi6and2fokqess5tojy2u	416	172	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	416	173	Vector	Vector	NNP
work_dbbvwgi6and2fokqess5tojy2u	416	174	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	416	175	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	417	1	Lysate	lysate	NN
work_dbbvwgi6and2fokqess5tojy2u	417	2	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	417	3	immunoblot	immunoblot	NN
work_dbbvwgi6and2fokqess5tojy2u	417	4	Mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	417	5	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	417	6	euthanized	euthanize	VBN
work_dbbvwgi6and2fokqess5tojy2u	417	7	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	417	8	cervical	cervical	JJ
work_dbbvwgi6and2fokqess5tojy2u	417	9	dislocation	dislocation	NN
work_dbbvwgi6and2fokqess5tojy2u	417	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	418	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	418	2	organs	organ	NNS
work_dbbvwgi6and2fokqess5tojy2u	418	3	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	418	4	collected	collect	VBN
work_dbbvwgi6and2fokqess5tojy2u	418	5	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	418	6	frozen	freeze	VBN
work_dbbvwgi6and2fokqess5tojy2u	418	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	418	8	liquid	liquid	JJ
work_dbbvwgi6and2fokqess5tojy2u	418	9	nitrogen	nitrogen	NN
work_dbbvwgi6and2fokqess5tojy2u	418	10	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	418	11	stored	store	VBD
work_dbbvwgi6and2fokqess5tojy2u	418	12	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	418	13	-80	-80	NNP
work_dbbvwgi6and2fokqess5tojy2u	418	14	°	°	NNP
work_dbbvwgi6and2fokqess5tojy2u	418	15	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	418	16	until	until	IN
work_dbbvwgi6and2fokqess5tojy2u	418	17	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	418	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	419	1	Tissues	tissue	NNS
work_dbbvwgi6and2fokqess5tojy2u	419	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	419	3	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	419	4	fibroblasts	fibroblast	NNS
work_dbbvwgi6and2fokqess5tojy2u	419	5	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	419	6	U2OS	U2OS	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	7	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	419	8	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	419	9	prepared	prepare	VBN
work_dbbvwgi6and2fokqess5tojy2u	419	10	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	419	11	lysis	lysis	NN
work_dbbvwgi6and2fokqess5tojy2u	419	12	buffer	buffer	NN
work_dbbvwgi6and2fokqess5tojy2u	419	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	419	14	consisting	consist	VBG
work_dbbvwgi6and2fokqess5tojy2u	419	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	419	16	50	50	CD
work_dbbvwgi6and2fokqess5tojy2u	419	17	mM	mM	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	18	TrisHCl	TrisHCl	NNS
work_dbbvwgi6and2fokqess5tojy2u	419	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	419	20	pH	pH	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	21	7.5	7.5	CD
work_dbbvwgi6and2fokqess5tojy2u	419	22	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	419	23	150	150	CD
work_dbbvwgi6and2fokqess5tojy2u	419	24	mM	mm	NN
work_dbbvwgi6and2fokqess5tojy2u	419	25	NaCl	NaCl	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	26	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	419	27	0.5	0.5	CD
work_dbbvwgi6and2fokqess5tojy2u	419	28	%	%	NN
work_dbbvwgi6and2fokqess5tojy2u	419	29	NP40	NP40	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	30	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	419	31	50	50	CD
work_dbbvwgi6and2fokqess5tojy2u	419	32	mM	mM	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	33	β	β	NN
work_dbbvwgi6and2fokqess5tojy2u	419	34	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	419	35	glycerophosphate	glycerophosphate	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	36	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	419	37	50	50	CD
work_dbbvwgi6and2fokqess5tojy2u	419	38	mM	mm	NN
work_dbbvwgi6and2fokqess5tojy2u	419	39	NaF	naf	NN
work_dbbvwgi6and2fokqess5tojy2u	419	40	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	419	41	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	419	42	mM	mM	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	43	sodium	sodium	NN
work_dbbvwgi6and2fokqess5tojy2u	419	44	vanadate	vanadate	NN
work_dbbvwgi6and2fokqess5tojy2u	419	45	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	419	46	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	419	47	mM	mM	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	48	phenyl	phenyl	NN
work_dbbvwgi6and2fokqess5tojy2u	419	49	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	419	50	methylsulfonyl	methylsulfonyl	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	51	fluoride	fluoride	NN
work_dbbvwgi6and2fokqess5tojy2u	419	52	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	419	53	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	419	54	μg	μg	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	55	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	419	56	mL	mL	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	57	leupeptin	leupeptin	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	58	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	419	59	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	419	60	μg	μg	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	61	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	419	62	mL	mL	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	63	aprotinin	aprotinin	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	64	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	419	65	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	419	66	μg/	μg/	NN
work_dbbvwgi6and2fokqess5tojy2u	419	67	mL	mL	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	68	pepstatin	pepstatin	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	69	-	-	:
work_dbbvwgi6and2fokqess5tojy2u	419	70	A	a	NN
work_dbbvwgi6and2fokqess5tojy2u	419	71	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	419	72	benzamidine	benzamidine	NN
work_dbbvwgi6and2fokqess5tojy2u	419	73	100	100	CD
work_dbbvwgi6and2fokqess5tojy2u	419	74	μg	μg	JJ
work_dbbvwgi6and2fokqess5tojy2u	419	75	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	419	76	mL	ml	NN
work_dbbvwgi6and2fokqess5tojy2u	419	77	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	419	78	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	419	79	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	419	80	tissues	tissue	NNS
work_dbbvwgi6and2fokqess5tojy2u	419	81	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	419	82	homogenized	homogenize	VBN
work_dbbvwgi6and2fokqess5tojy2u	419	83	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	419	84	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	419	85	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	419	86	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	419	87	driven	drive	VBN
work_dbbvwgi6and2fokqess5tojy2u	419	88	Polytron	Polytron	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	89	PT3000	PT3000	NNP
work_dbbvwgi6and2fokqess5tojy2u	419	90	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	420	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	420	2	lysates	lysate	NNS
work_dbbvwgi6and2fokqess5tojy2u	420	3	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	420	4	incubated	incubate	VBN
work_dbbvwgi6and2fokqess5tojy2u	420	5	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	420	6	ice	ice	NN
work_dbbvwgi6and2fokqess5tojy2u	420	7	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	420	8	20	20	CD
work_dbbvwgi6and2fokqess5tojy2u	420	9	minutes	minute	NNS
work_dbbvwgi6and2fokqess5tojy2u	420	10	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	420	11	centrifuged	centrifuge	VBD
work_dbbvwgi6and2fokqess5tojy2u	420	12	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	420	13	13,000	13,000	CD
work_dbbvwgi6and2fokqess5tojy2u	420	14	g	g	NN
work_dbbvwgi6and2fokqess5tojy2u	420	15	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	420	16	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	420	17	minutes	minute	NNS
work_dbbvwgi6and2fokqess5tojy2u	420	18	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	420	19	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	420	20	°	°	NNS
work_dbbvwgi6and2fokqess5tojy2u	420	21	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	420	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	421	1	Total	total	JJ
work_dbbvwgi6and2fokqess5tojy2u	421	2	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	421	3	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	421	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	421	5	measured	measure	VBN
work_dbbvwgi6and2fokqess5tojy2u	421	6	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	421	7	BCA	BCA	NNP
work_dbbvwgi6and2fokqess5tojy2u	421	8	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	421	9	Pierce	Pierce	NNP
work_dbbvwgi6and2fokqess5tojy2u	421	10	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	421	11	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	422	1	Equal	equal	JJ
work_dbbvwgi6and2fokqess5tojy2u	422	2	amounts	amount	NNS
work_dbbvwgi6and2fokqess5tojy2u	422	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	422	4	supernatant	supernatant	JJ
work_dbbvwgi6and2fokqess5tojy2u	422	5	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	422	6	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	422	7	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	422	8	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	422	9	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	422	10	Tris	Tris	NNP
work_dbbvwgi6and2fokqess5tojy2u	422	11	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	422	12	acetate	acetate	NNP
work_dbbvwgi6and2fokqess5tojy2u	422	13	PAGE	page	NN
work_dbbvwgi6and2fokqess5tojy2u	422	14	system	system	NN
work_dbbvwgi6and2fokqess5tojy2u	422	15	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	422	16	63	63	CD
work_dbbvwgi6and2fokqess5tojy2u	422	17	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	422	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	423	1	Band	band	NN
work_dbbvwgi6and2fokqess5tojy2u	423	2	intensities	intensity	NNS
work_dbbvwgi6and2fokqess5tojy2u	423	3	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	423	4	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	423	5	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	423	6	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	423	7	gel	gel	NN
work_dbbvwgi6and2fokqess5tojy2u	423	8	documentation	documentation	NN
work_dbbvwgi6and2fokqess5tojy2u	423	9	system	system	NN
work_dbbvwgi6and2fokqess5tojy2u	423	10	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	423	11	LAS-3000	LAS-3000	NNP
work_dbbvwgi6and2fokqess5tojy2u	423	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	423	13	Fujifilm	Fujifilm	NNP
work_dbbvwgi6and2fokqess5tojy2u	423	14	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	423	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	424	1	Proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	424	2	levels	level	NNS
work_dbbvwgi6and2fokqess5tojy2u	424	3	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	424	4	normalized	normalize	VBN
work_dbbvwgi6and2fokqess5tojy2u	424	5	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	424	6	expressed	express	VBN
work_dbbvwgi6and2fokqess5tojy2u	424	7	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	424	8	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	424	9	percentage	percentage	NN
work_dbbvwgi6and2fokqess5tojy2u	424	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	424	11	controls	control	NNS
work_dbbvwgi6and2fokqess5tojy2u	424	12	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	425	1	statistical	statistical	JJ
work_dbbvwgi6and2fokqess5tojy2u	425	2	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	425	3	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	425	4	results	result	NNS
work_dbbvwgi6and2fokqess5tojy2u	425	5	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	425	6	expressed	express	VBN
work_dbbvwgi6and2fokqess5tojy2u	425	7	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	425	8	mean±SEM	mean±SEM	NNP
work_dbbvwgi6and2fokqess5tojy2u	425	9	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	426	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	426	2	data	datum	NNS
work_dbbvwgi6and2fokqess5tojy2u	426	3	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	426	4	analyzed	analyze	VBN
work_dbbvwgi6and2fokqess5tojy2u	426	5	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	426	6	one	one	CD
work_dbbvwgi6and2fokqess5tojy2u	426	7	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	426	8	way	way	NN
work_dbbvwgi6and2fokqess5tojy2u	426	9	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	426	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	426	11	variance	variance	NN
work_dbbvwgi6and2fokqess5tojy2u	426	12	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	426	13	ANOVA	ANOVA	NNP
work_dbbvwgi6and2fokqess5tojy2u	426	14	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	426	15	or	or	CC
work_dbbvwgi6and2fokqess5tojy2u	426	16	Student	student	NN
work_dbbvwgi6and2fokqess5tojy2u	426	17	’s	’s	POS
work_dbbvwgi6and2fokqess5tojy2u	426	18	t	t	NN
work_dbbvwgi6and2fokqess5tojy2u	426	19	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	426	20	test	test	NN
work_dbbvwgi6and2fokqess5tojy2u	426	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	427	1	For	for	IN
work_dbbvwgi6and2fokqess5tojy2u	427	2	comparison	comparison	NN
work_dbbvwgi6and2fokqess5tojy2u	427	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	427	4	significance	significance	NN
work_dbbvwgi6and2fokqess5tojy2u	427	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	427	6	Tukey	Tukey	NNP
work_dbbvwgi6and2fokqess5tojy2u	427	7	’s	’s	POS
work_dbbvwgi6and2fokqess5tojy2u	427	8	test	test	NN
work_dbbvwgi6and2fokqess5tojy2u	427	9	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	427	10	used	use	VBN
work_dbbvwgi6and2fokqess5tojy2u	427	11	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	427	12	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	427	13	post	post	FW
work_dbbvwgi6and2fokqess5tojy2u	427	14	hoc	hoc	FW
work_dbbvwgi6and2fokqess5tojy2u	427	15	test	test	NN
work_dbbvwgi6and2fokqess5tojy2u	427	16	according	accord	VBG
work_dbbvwgi6and2fokqess5tojy2u	427	17	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	427	18	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	427	19	statistical	statistical	JJ
work_dbbvwgi6and2fokqess5tojy2u	427	20	program	program	NN
work_dbbvwgi6and2fokqess5tojy2u	427	21	GraphPad	GraphPad	NNP
work_dbbvwgi6and2fokqess5tojy2u	427	22	Prism	Prism	NNP
work_dbbvwgi6and2fokqess5tojy2u	427	23	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	428	1	Differences	difference	NNS
work_dbbvwgi6and2fokqess5tojy2u	428	2	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	428	3	considered	consider	VBN
work_dbbvwgi6and2fokqess5tojy2u	428	4	significant	significant	JJ
work_dbbvwgi6and2fokqess5tojy2u	428	5	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	428	6	p	p	NN
work_dbbvwgi6and2fokqess5tojy2u	428	7	values	value	NNS
work_dbbvwgi6and2fokqess5tojy2u	428	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	428	9	less	less	JJR
work_dbbvwgi6and2fokqess5tojy2u	428	10	than	than	IN
work_dbbvwgi6and2fokqess5tojy2u	428	11	0.05	0.05	CD
work_dbbvwgi6and2fokqess5tojy2u	428	12	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	428	13	*	*	NFP
work_dbbvwgi6and2fokqess5tojy2u	428	14	p	p	NN
work_dbbvwgi6and2fokqess5tojy2u	428	15	<	<	XX
work_dbbvwgi6and2fokqess5tojy2u	428	16	0.05	0.05	CD
work_dbbvwgi6and2fokqess5tojy2u	428	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	428	18	*	*	NFP
work_dbbvwgi6and2fokqess5tojy2u	428	19	*	*	NFP
work_dbbvwgi6and2fokqess5tojy2u	428	20	p	p	NN
work_dbbvwgi6and2fokqess5tojy2u	428	21	<	<	XX
work_dbbvwgi6and2fokqess5tojy2u	428	22	0.01	0.01	XX
work_dbbvwgi6and2fokqess5tojy2u	428	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	428	24	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	428	25	*	*	NFP
work_dbbvwgi6and2fokqess5tojy2u	428	26	*	*	NFP
work_dbbvwgi6and2fokqess5tojy2u	428	27	*	*	NFP
work_dbbvwgi6and2fokqess5tojy2u	428	28	p	p	NN
work_dbbvwgi6and2fokqess5tojy2u	428	29	<	<	XX
work_dbbvwgi6and2fokqess5tojy2u	428	30	0.001	0.001	CD
work_dbbvwgi6and2fokqess5tojy2u	428	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	429	1	AckNOwLEDGMENts	AckNOwLEDGMENts	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	2	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	429	3	would	would	MD
work_dbbvwgi6and2fokqess5tojy2u	429	4	like	like	VB
work_dbbvwgi6and2fokqess5tojy2u	429	5	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	429	6	thank	thank	VB
work_dbbvwgi6and2fokqess5tojy2u	429	7	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	429	8	Sanger	Sanger	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	9	Institute	Institute	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	10	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	429	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	429	12	ES	ES	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	13	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	429	14	line	line	NN
work_dbbvwgi6and2fokqess5tojy2u	429	15	AR0530	AR0530	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	429	17	J.	J.	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	18	Martin	Martin	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	19	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	429	20	Caballero	Caballero	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	21	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	429	22	p53-/-	p53-/-	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	23	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	429	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	429	25	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	429	26	A.	a.	NN
work_dbbvwgi6and2fokqess5tojy2u	429	27	Gimeno	Gimeno	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	28	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	429	29	E.	E.	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	30	Adanero	Adanero	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	31	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	429	32	A.	A.	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	33	Angelo	Angelo	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	34	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	429	35	E.	E.	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	36	Castaño	Castaño	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	37	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	429	38	B.	B.	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	39	Torrejon	Torrejon	NNP
work_dbbvwgi6and2fokqess5tojy2u	429	40	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	429	41	technical	technical	JJ
work_dbbvwgi6and2fokqess5tojy2u	429	42	assistance	assistance	NN
work_dbbvwgi6and2fokqess5tojy2u	429	43	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	430	1	We	-PRON-	PRP
work_dbbvwgi6and2fokqess5tojy2u	430	2	also	also	RB
work_dbbvwgi6and2fokqess5tojy2u	430	3	acknowledge	acknowledge	VBP
work_dbbvwgi6and2fokqess5tojy2u	430	4	S.	S.	NNP
work_dbbvwgi6and2fokqess5tojy2u	430	5	Sánchez	Sánchez	NNP
work_dbbvwgi6and2fokqess5tojy2u	430	6	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	430	7	Tena	Tena	NNP
work_dbbvwgi6and2fokqess5tojy2u	430	8	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	430	9	valuable	valuable	JJ
work_dbbvwgi6and2fokqess5tojy2u	430	10	discussion	discussion	NN
work_dbbvwgi6and2fokqess5tojy2u	430	11	throughout	throughout	IN
work_dbbvwgi6and2fokqess5tojy2u	430	12	this	this	DT
work_dbbvwgi6and2fokqess5tojy2u	430	13	study	study	NN
work_dbbvwgi6and2fokqess5tojy2u	430	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	430	15	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	430	16	G.	G.	NNP
work_dbbvwgi6and2fokqess5tojy2u	430	17	Alvarez	Alvarez	NNP
work_dbbvwgi6and2fokqess5tojy2u	430	18	de	de	NNP
work_dbbvwgi6and2fokqess5tojy2u	430	19	Toledo	Toledo	NNP
work_dbbvwgi6and2fokqess5tojy2u	430	20	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	430	21	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	430	22	facilities	facility	NNS
work_dbbvwgi6and2fokqess5tojy2u	430	23	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	430	24	use	use	VB
work_dbbvwgi6and2fokqess5tojy2u	430	25	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	430	26	FluoView	FluoView	NNP
work_dbbvwgi6and2fokqess5tojy2u	430	27	1000	1000	CD
work_dbbvwgi6and2fokqess5tojy2u	430	28	laser	laser	NN
work_dbbvwgi6and2fokqess5tojy2u	430	29	confocal	confocal	JJ
work_dbbvwgi6and2fokqess5tojy2u	430	30	scanning	scanning	NN
work_dbbvwgi6and2fokqess5tojy2u	430	31	microscope	microscope	NN
work_dbbvwgi6and2fokqess5tojy2u	430	32	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	431	1	RR	RR	NNP
work_dbbvwgi6and2fokqess5tojy2u	431	2	held	hold	VBD
work_dbbvwgi6and2fokqess5tojy2u	431	3	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	431	4	Juan	Juan	NNP
work_dbbvwgi6and2fokqess5tojy2u	431	5	de	de	FW
work_dbbvwgi6and2fokqess5tojy2u	431	6	la	la	NNP
work_dbbvwgi6and2fokqess5tojy2u	431	7	Cierva	Cierva	NNP
work_dbbvwgi6and2fokqess5tojy2u	431	8	contract	contract	NN
work_dbbvwgi6and2fokqess5tojy2u	431	9	JCI-2011	JCI-2011	NNP
work_dbbvwgi6and2fokqess5tojy2u	431	10	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	431	11	08888	08888	CD
work_dbbvwgi6and2fokqess5tojy2u	431	12	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	431	13	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	431	14	MINECO	MINECO	NNP
work_dbbvwgi6and2fokqess5tojy2u	431	15	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	431	16	VPPI	VPPI	NNP
work_dbbvwgi6and2fokqess5tojy2u	431	17	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	431	18	US	US	NNP
work_dbbvwgi6and2fokqess5tojy2u	431	19	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	431	20	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	431	21	University	University	NNP
work_dbbvwgi6and2fokqess5tojy2u	431	22	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	431	23	Sevilla	Sevilla	NNP
work_dbbvwgi6and2fokqess5tojy2u	431	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	432	1	TS	TS	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	2	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	432	3	LP	LP	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	4	were	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	432	5	supported	support	VBN
work_dbbvwgi6and2fokqess5tojy2u	432	6	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	432	7	fellowships	fellowship	NNS
work_dbbvwgi6and2fokqess5tojy2u	432	8	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	432	9	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	432	10	CAPES	CAPES	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	11	Foundation	Foundation	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	12	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	432	13	Ministry	Ministry	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	14	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	432	15	Education	Education	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	16	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	432	17	Brazil	Brazil	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	18	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	432	19	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	432	20	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	432	21	CNPq	CNPq	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	22	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	432	23	Programa	Programa	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	24	Ciências	Ciências	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	25	sem	sem	NN
work_dbbvwgi6and2fokqess5tojy2u	432	26	Fronteiras	Fronteiras	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	27	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	432	28	Ministry	Ministry	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	29	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	432	30	Science	Science	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	31	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	432	32	Technology	Technology	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	33	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	432	34	Innovation	Innovation	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	35	Education	Education	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	36	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	432	37	Brazil	Brazil	NNP
work_dbbvwgi6and2fokqess5tojy2u	432	38	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	432	39	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	432	40	respectively	respectively	RB
work_dbbvwgi6and2fokqess5tojy2u	432	41	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	433	1	This	this	DT
work_dbbvwgi6and2fokqess5tojy2u	433	2	article	article	NN
work_dbbvwgi6and2fokqess5tojy2u	433	3	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	433	4	based	base	VBN
work_dbbvwgi6and2fokqess5tojy2u	433	5	upon	upon	IN
work_dbbvwgi6and2fokqess5tojy2u	433	6	work	work	NN
work_dbbvwgi6and2fokqess5tojy2u	433	7	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	433	8	COST	COST	NNP
work_dbbvwgi6and2fokqess5tojy2u	433	9	Action	Action	NNP
work_dbbvwgi6and2fokqess5tojy2u	433	10	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	433	11	PROTEOSTASIS	PROTEOSTASIS	NNP
work_dbbvwgi6and2fokqess5tojy2u	433	12	BM1307	BM1307	NNP
work_dbbvwgi6and2fokqess5tojy2u	433	13	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	433	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	433	15	supported	support	VBN
work_dbbvwgi6and2fokqess5tojy2u	433	16	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	433	17	COST	COST	NNS
work_dbbvwgi6and2fokqess5tojy2u	433	18	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	433	19	European	European	NNP
work_dbbvwgi6and2fokqess5tojy2u	433	20	Cooperation	Cooperation	NNP
work_dbbvwgi6and2fokqess5tojy2u	433	21	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	433	22	Science	Science	NNP
work_dbbvwgi6and2fokqess5tojy2u	433	23	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	433	24	Technology	Technology	NNP
work_dbbvwgi6and2fokqess5tojy2u	433	25	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	433	26	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	434	1	cONFLIcts	conflict	NNS
work_dbbvwgi6and2fokqess5tojy2u	434	2	OF	of	IN
work_dbbvwgi6and2fokqess5tojy2u	434	3	INtErEst	INtErEst	NNP
work_dbbvwgi6and2fokqess5tojy2u	434	4	All	all	DT
work_dbbvwgi6and2fokqess5tojy2u	434	5	authors	author	NNS
work_dbbvwgi6and2fokqess5tojy2u	434	6	have	have	VBP
work_dbbvwgi6and2fokqess5tojy2u	434	7	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	434	8	conflicts	conflict	NNS
work_dbbvwgi6and2fokqess5tojy2u	434	9	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	434	10	interest	interest	NN
work_dbbvwgi6and2fokqess5tojy2u	434	11	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	434	12	disclose	disclose	VB
work_dbbvwgi6and2fokqess5tojy2u	434	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	435	1	GrANt	GrANt	NNP
work_dbbvwgi6and2fokqess5tojy2u	435	2	sUPPOrt	sUPPOrt	NNP
work_dbbvwgi6and2fokqess5tojy2u	435	3	This	this	DT
work_dbbvwgi6and2fokqess5tojy2u	435	4	work	work	NN
work_dbbvwgi6and2fokqess5tojy2u	435	5	was	be	VBD
work_dbbvwgi6and2fokqess5tojy2u	435	6	supported	support	VBN
work_dbbvwgi6and2fokqess5tojy2u	435	7	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	435	8	grants	grant	NNS
work_dbbvwgi6and2fokqess5tojy2u	435	9	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	435	10	Spanish	Spanish	NNP
work_dbbvwgi6and2fokqess5tojy2u	435	11	Ministerio	Ministerio	NNP
work_dbbvwgi6and2fokqess5tojy2u	435	12	de	de	IN
work_dbbvwgi6and2fokqess5tojy2u	435	13	Ciencia	Ciencia	NNP
work_dbbvwgi6and2fokqess5tojy2u	435	14	e	e	NN
work_dbbvwgi6and2fokqess5tojy2u	435	15	Innovación	Innovación	NNP
work_dbbvwgi6and2fokqess5tojy2u	435	16	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	435	17	BFU2011	BFU2011	NNP
work_dbbvwgi6and2fokqess5tojy2u	435	18	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	435	19	22498	22498	CD
work_dbbvwgi6and2fokqess5tojy2u	435	20	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	435	21	J.L.R.	J.L.R.	NNP
work_dbbvwgi6and2fokqess5tojy2u	436	1	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	436	2	BFU2014	BFU2014	NNP
work_dbbvwgi6and2fokqess5tojy2u	436	3	-	-	:
work_dbbvwgi6and2fokqess5tojy2u	436	4	56313P	56313P	NNP
work_dbbvwgi6and2fokqess5tojy2u	436	5	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	436	6	F.V.	F.V.	NNP
work_dbbvwgi6and2fokqess5tojy2u	436	7	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	437	1	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	437	2	Brazilian	Brazilian	NNP
work_dbbvwgi6and2fokqess5tojy2u	437	3	Scientific	Scientific	NNP
work_dbbvwgi6and2fokqess5tojy2u	437	4	Program	Program	NNP
work_dbbvwgi6and2fokqess5tojy2u	437	5	“	"	``
work_dbbvwgi6and2fokqess5tojy2u	437	6	Ciências	Ciências	NNP
work_dbbvwgi6and2fokqess5tojy2u	437	7	sem	sem	NN
work_dbbvwgi6and2fokqess5tojy2u	437	8	Fronteiras	Fronteiras	NNPS
work_dbbvwgi6and2fokqess5tojy2u	437	9	”	"	''
work_dbbvwgi6and2fokqess5tojy2u	437	10	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	437	11	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	437	12	Ministry	Ministry	NNP
work_dbbvwgi6and2fokqess5tojy2u	437	13	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	437	14	Science	Science	NNP
work_dbbvwgi6and2fokqess5tojy2u	437	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	437	16	Technology	Technology	NNP
work_dbbvwgi6and2fokqess5tojy2u	437	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	437	18	Innovation	Innovation	NNP
work_dbbvwgi6and2fokqess5tojy2u	437	19	Education	Education	NNP
work_dbbvwgi6and2fokqess5tojy2u	437	20	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	437	21	Brazil	Brazil	NNP
work_dbbvwgi6and2fokqess5tojy2u	437	22	[	[	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	437	23	313600/2013	313600/2013	CD
work_dbbvwgi6and2fokqess5tojy2u	437	24	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	437	25	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	437	26	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	437	27	J.L.R.	J.L.R.	NNP
work_dbbvwgi6and2fokqess5tojy2u	438	1	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	438	2	400422/2013	400422/2013	CD
work_dbbvwgi6and2fokqess5tojy2u	438	3	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	438	4	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	438	5	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	438	6	J.R.O.	J.R.O.	NNP
work_dbbvwgi6and2fokqess5tojy2u	438	7	]	]	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	438	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	439	1	Editorial	editorial	NN
work_dbbvwgi6and2fokqess5tojy2u	439	2	note	note	NN
work_dbbvwgi6and2fokqess5tojy2u	439	3	This	this	DT
work_dbbvwgi6and2fokqess5tojy2u	439	4	paper	paper	NN
work_dbbvwgi6and2fokqess5tojy2u	439	5	has	have	VBZ
work_dbbvwgi6and2fokqess5tojy2u	439	6	been	be	VBN
work_dbbvwgi6and2fokqess5tojy2u	439	7	accepted	accept	VBN
work_dbbvwgi6and2fokqess5tojy2u	439	8	based	base	VBN
work_dbbvwgi6and2fokqess5tojy2u	439	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	439	10	part	part	NN
work_dbbvwgi6and2fokqess5tojy2u	439	11	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	439	12	peer-	peer-	JJ
work_dbbvwgi6and2fokqess5tojy2u	439	13	review	review	NN
work_dbbvwgi6and2fokqess5tojy2u	439	14	conducted	conduct	VBN
work_dbbvwgi6and2fokqess5tojy2u	439	15	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	439	16	another	another	DT
work_dbbvwgi6and2fokqess5tojy2u	439	17	journal	journal	NN
work_dbbvwgi6and2fokqess5tojy2u	439	18	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	439	19	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	439	20	authors	author	NNS
work_dbbvwgi6and2fokqess5tojy2u	439	21	’	’	POS
work_dbbvwgi6and2fokqess5tojy2u	439	22	response	response	NN
work_dbbvwgi6and2fokqess5tojy2u	439	23	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	439	24	revisions	revision	NNS
work_dbbvwgi6and2fokqess5tojy2u	439	25	as	as	RB
work_dbbvwgi6and2fokqess5tojy2u	439	26	well	well	RB
work_dbbvwgi6and2fokqess5tojy2u	439	27	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	439	28	expedited	expedited	JJ
work_dbbvwgi6and2fokqess5tojy2u	439	29	peer	peer	NN
work_dbbvwgi6and2fokqess5tojy2u	439	30	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	439	31	review	review	NN
work_dbbvwgi6and2fokqess5tojy2u	439	32	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	439	33	Oncotarget	Oncotarget	NNP
work_dbbvwgi6and2fokqess5tojy2u	439	34	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	440	1	rEFErENcEs	references	ADD
work_dbbvwgi6and2fokqess5tojy2u	440	2	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	440	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	441	1	Williams	Williams	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	2	CA	CA	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	441	4	Beaudet	Beaudet	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	5	AL	AL	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	441	7	Clayton	Clayton	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	8	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	441	9	Smith	Smith	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	10	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	441	12	Knoll	Knoll	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	13	JH	JH	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	441	15	Kyllerman	Kyllerman	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	16	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	441	18	Laan	Laan	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	19	LA	LA	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	441	21	Magenis	Magenis	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	22	RE	RE	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	441	24	Moncla	Moncla	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	25	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	26	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	441	27	Schinzel	Schinzel	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	28	AA	AA	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	29	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	441	30	Summers	Summers	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	31	JA	JA	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	32	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	441	33	Wagstaff	Wagstaff	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	34	J.	J.	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	35	Angelman	Angelman	NNP
work_dbbvwgi6and2fokqess5tojy2u	441	36	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	441	37	2005	2005	CD
work_dbbvwgi6and2fokqess5tojy2u	441	38	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	441	39	updated	update	VBN
work_dbbvwgi6and2fokqess5tojy2u	441	40	consensus	consensus	NN
work_dbbvwgi6and2fokqess5tojy2u	441	41	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	441	42	diagnostic	diagnostic	JJ
work_dbbvwgi6and2fokqess5tojy2u	441	43	criteria	criterion	NNS
work_dbbvwgi6and2fokqess5tojy2u	441	44	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	442	1	Am	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	442	2	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	442	3	Med	Med	NNP
work_dbbvwgi6and2fokqess5tojy2u	442	4	Genet	Genet	NNP
work_dbbvwgi6and2fokqess5tojy2u	442	5	A.	a.	NN
work_dbbvwgi6and2fokqess5tojy2u	443	1	2006	2006	CD
work_dbbvwgi6and2fokqess5tojy2u	443	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	443	3	140	140	CD
work_dbbvwgi6and2fokqess5tojy2u	443	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	443	5	413	413	CD
work_dbbvwgi6and2fokqess5tojy2u	443	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	443	7	418	418	CD
work_dbbvwgi6and2fokqess5tojy2u	443	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	444	1	2	2	LS
work_dbbvwgi6and2fokqess5tojy2u	444	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	445	1	Mabb	Mabb	NNP
work_dbbvwgi6and2fokqess5tojy2u	445	2	AM	AM	NNP
work_dbbvwgi6and2fokqess5tojy2u	445	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	445	4	Judson	Judson	NNP
work_dbbvwgi6and2fokqess5tojy2u	445	5	MC	MC	NNP
work_dbbvwgi6and2fokqess5tojy2u	445	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	445	7	Zylka	Zylka	NNP
work_dbbvwgi6and2fokqess5tojy2u	445	8	MJ	MJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	445	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	445	10	Philpot	Philpot	NNP
work_dbbvwgi6and2fokqess5tojy2u	445	11	BD	BD	NNP
work_dbbvwgi6and2fokqess5tojy2u	445	12	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	446	1	Angelman	angelman	NN
work_dbbvwgi6and2fokqess5tojy2u	446	2	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	446	3	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	446	4	insights	insight	NNS
work_dbbvwgi6and2fokqess5tojy2u	446	5	into	into	IN
work_dbbvwgi6and2fokqess5tojy2u	446	6	genomic	genomic	JJ
work_dbbvwgi6and2fokqess5tojy2u	446	7	imprinting	imprinting	NN
work_dbbvwgi6and2fokqess5tojy2u	446	8	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	446	9	neurodevelopmental	neurodevelopmental	JJ
work_dbbvwgi6and2fokqess5tojy2u	446	10	phenotypes	phenotype	NNS
work_dbbvwgi6and2fokqess5tojy2u	446	11	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	447	1	Trends	Trends	NNPS
work_dbbvwgi6and2fokqess5tojy2u	447	2	Neurosci	Neurosci	NNP
work_dbbvwgi6and2fokqess5tojy2u	447	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	448	1	2011	2011	CD
work_dbbvwgi6and2fokqess5tojy2u	448	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	448	3	34	34	CD
work_dbbvwgi6and2fokqess5tojy2u	448	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	448	5	293	293	CD
work_dbbvwgi6and2fokqess5tojy2u	448	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	448	7	303	303	CD
work_dbbvwgi6and2fokqess5tojy2u	448	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	449	1	3	3	LS
work_dbbvwgi6and2fokqess5tojy2u	449	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	450	1	Williams	Williams	NNP
work_dbbvwgi6and2fokqess5tojy2u	450	2	CA	CA	NNP
work_dbbvwgi6and2fokqess5tojy2u	450	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	450	4	Driscoll	Driscoll	NNP
work_dbbvwgi6and2fokqess5tojy2u	450	5	DJ	DJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	450	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	450	7	Dagli	Dagli	NNP
work_dbbvwgi6and2fokqess5tojy2u	450	8	AI	AI	NNP
work_dbbvwgi6and2fokqess5tojy2u	450	9	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	451	1	Clinical	clinical	JJ
work_dbbvwgi6and2fokqess5tojy2u	451	2	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	451	3	genetic	genetic	JJ
work_dbbvwgi6and2fokqess5tojy2u	451	4	aspects	aspect	NNS
work_dbbvwgi6and2fokqess5tojy2u	451	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	451	6	Angelman	Angelman	NNP
work_dbbvwgi6and2fokqess5tojy2u	451	7	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	451	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	452	1	Genet	Genet	NNP
work_dbbvwgi6and2fokqess5tojy2u	452	2	Med	Med	NNP
work_dbbvwgi6and2fokqess5tojy2u	452	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	453	1	2010	2010	CD
work_dbbvwgi6and2fokqess5tojy2u	453	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	453	3	12	12	CD
work_dbbvwgi6and2fokqess5tojy2u	453	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	453	5	385-	385-	CD
work_dbbvwgi6and2fokqess5tojy2u	453	6	395	395	CD
work_dbbvwgi6and2fokqess5tojy2u	453	7	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	454	1	4	4	LS
work_dbbvwgi6and2fokqess5tojy2u	454	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	455	1	Puffenberger	Puffenberger	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	2	EG	EG	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	455	4	Jinks	Jinks	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	5	RN	RN	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	455	7	Wang	Wang	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	8	H	H	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	455	10	Xin	Xin	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	11	B	B	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	455	13	Fiorentini	Fiorentini	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	14	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	455	16	Sherman	Sherman	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	17	EA	EA	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	455	19	Degrazio	Degrazio	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	20	D	D	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	455	22	Shaw	Shaw	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	23	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	455	25	Sougnez	Sougnez	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	26	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	27	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	455	28	Cibulskis	Cibulskis	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	29	K	K	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	30	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	455	31	Gabriel	Gabriel	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	32	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	33	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	455	34	Kelley	Kelley	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	35	RI	RI	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	36	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	455	37	Morton	Morton	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	38	DH	DH	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	39	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	455	40	et	et	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	41	al	al	NNP
work_dbbvwgi6and2fokqess5tojy2u	455	42	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	456	1	A	a	DT
work_dbbvwgi6and2fokqess5tojy2u	456	2	homozygous	homozygous	JJ
work_dbbvwgi6and2fokqess5tojy2u	456	3	missense	missense	NN
work_dbbvwgi6and2fokqess5tojy2u	456	4	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	456	5	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	456	6	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	456	7	associated	associate	VBN
work_dbbvwgi6and2fokqess5tojy2u	456	8	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	456	9	global	global	JJ
work_dbbvwgi6and2fokqess5tojy2u	456	10	developmental	developmental	JJ
work_dbbvwgi6and2fokqess5tojy2u	456	11	delay	delay	NN
work_dbbvwgi6and2fokqess5tojy2u	456	12	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	456	13	autism	autism	NN
work_dbbvwgi6and2fokqess5tojy2u	456	14	spectrum	spectrum	NNP
work_dbbvwgi6and2fokqess5tojy2u	456	15	disorder	disorder	NNP
work_dbbvwgi6and2fokqess5tojy2u	456	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	457	1	Hum	Hum	NNP
work_dbbvwgi6and2fokqess5tojy2u	457	2	Mutat	Mutat	NNP
work_dbbvwgi6and2fokqess5tojy2u	457	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	458	1	2012	2012	CD
work_dbbvwgi6and2fokqess5tojy2u	458	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	458	3	33	33	CD
work_dbbvwgi6and2fokqess5tojy2u	458	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	458	5	1639	1639	CD
work_dbbvwgi6and2fokqess5tojy2u	458	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	458	7	1646	1646	CD
work_dbbvwgi6and2fokqess5tojy2u	458	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	459	1	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	459	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	460	1	Harlalka	Harlalka	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	2	G	G	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	3	V	V	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	460	5	Baple	Baple	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	6	EL	EL	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	7	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	460	8	Cross	Cross	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	9	H	H	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	460	11	Kuhnle	Kuhnle	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	12	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	460	14	Cubillos-	Cubillos-	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	15	Rojas	Rojas	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	16	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	460	18	Matentzoglu	Matentzoglu	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	19	K	K	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	460	21	Patton	Patton	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	22	MA	MA	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	460	24	Wagner	Wagner	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	25	K	K	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	26	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	460	27	Coblentz	Coblentz	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	28	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	29	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	460	30	Ford	Ford	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	31	DL	DL	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	32	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	460	33	Mackay	Mackay	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	34	DJ	DJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	35	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	460	36	Chioza	Chioza	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	37	BA	BA	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	38	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	460	39	Scheffner	Scheffner	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	40	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	41	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	460	42	et	et	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	43	al	al	NNP
work_dbbvwgi6and2fokqess5tojy2u	460	44	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	461	1	Mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	461	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	461	3	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	461	4	causes	cause	VBZ
work_dbbvwgi6and2fokqess5tojy2u	461	5	developmental	developmental	JJ
work_dbbvwgi6and2fokqess5tojy2u	461	6	delay	delay	NN
work_dbbvwgi6and2fokqess5tojy2u	461	7	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	461	8	Angelman	Angelman	NNP
work_dbbvwgi6and2fokqess5tojy2u	461	9	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	461	10	like	like	JJ
work_dbbvwgi6and2fokqess5tojy2u	461	11	features	feature	NNS
work_dbbvwgi6and2fokqess5tojy2u	461	12	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	462	1	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	462	2	Med	Med	NNP
work_dbbvwgi6and2fokqess5tojy2u	462	3	Genet	Genet	NNP
work_dbbvwgi6and2fokqess5tojy2u	462	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	463	1	2013	2013	CD
work_dbbvwgi6and2fokqess5tojy2u	463	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	463	3	50	50	CD
work_dbbvwgi6and2fokqess5tojy2u	463	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	463	5	65	65	CD
work_dbbvwgi6and2fokqess5tojy2u	463	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	463	7	73	73	CD
work_dbbvwgi6and2fokqess5tojy2u	463	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	464	1	6	6	CD
work_dbbvwgi6and2fokqess5tojy2u	464	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	465	1	Cassidy	Cassidy	NNP
work_dbbvwgi6and2fokqess5tojy2u	465	2	SB	SB	NNP
work_dbbvwgi6and2fokqess5tojy2u	465	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	465	4	Schwartz	Schwartz	NNP
work_dbbvwgi6and2fokqess5tojy2u	465	5	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	465	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	465	7	Miller	Miller	NNP
work_dbbvwgi6and2fokqess5tojy2u	465	8	JL	JL	NNP
work_dbbvwgi6and2fokqess5tojy2u	465	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	465	10	Driscoll	Driscoll	NNP
work_dbbvwgi6and2fokqess5tojy2u	465	11	DJ	DJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	465	12	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	466	1	Prader-	Prader-	NNP
work_dbbvwgi6and2fokqess5tojy2u	466	2	Willi	Willi	NNP
work_dbbvwgi6and2fokqess5tojy2u	466	3	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	466	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	467	1	Genet	Genet	NNP
work_dbbvwgi6and2fokqess5tojy2u	467	2	Med	Med	NNP
work_dbbvwgi6and2fokqess5tojy2u	467	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	468	1	2012	2012	CD
work_dbbvwgi6and2fokqess5tojy2u	468	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	468	3	14	14	CD
work_dbbvwgi6and2fokqess5tojy2u	468	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	468	5	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	468	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	468	7	26	26	CD
work_dbbvwgi6and2fokqess5tojy2u	468	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	469	1	7	7	LS
work_dbbvwgi6and2fokqess5tojy2u	469	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	470	1	Kühnle	Kühnle	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	2	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	470	4	Kogel	Kogel	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	5	U	U	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	470	7	Glockzin	Glockzin	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	8	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	470	10	Marquardt	Marquardt	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	11	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	470	13	Ciechanover	Ciechanover	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	14	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	470	16	Matentzoglu	Matentzoglu	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	17	K	K	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	470	19	Scheffner	Scheffner	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	20	M.	M.	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	21	Physical	Physical	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	22	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	470	23	functional	functional	JJ
work_dbbvwgi6and2fokqess5tojy2u	470	24	interaction	interaction	NN
work_dbbvwgi6and2fokqess5tojy2u	470	25	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	470	26	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	470	27	HECT	HECT	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	28	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	470	29	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	470	30	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	470	31	ligases	ligase	NNS
work_dbbvwgi6and2fokqess5tojy2u	470	32	E6AP	E6AP	NNP
work_dbbvwgi6and2fokqess5tojy2u	470	33	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	470	34	Oncotarget56104www.impactjournals.com/oncotarget	Oncotarget56104www.impactjournals.com/oncotarget	''
work_dbbvwgi6and2fokqess5tojy2u	470	35	HERC2	herc2	JJ
work_dbbvwgi6and2fokqess5tojy2u	470	36	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	471	1	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	471	2	Biol	Biol	NNP
work_dbbvwgi6and2fokqess5tojy2u	471	3	Chem	Chem	NNP
work_dbbvwgi6and2fokqess5tojy2u	471	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	472	1	2011	2011	CD
work_dbbvwgi6and2fokqess5tojy2u	472	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	472	3	286	286	CD
work_dbbvwgi6and2fokqess5tojy2u	472	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	472	5	19410	19410	CD
work_dbbvwgi6and2fokqess5tojy2u	472	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	472	7	19416	19416	CD
work_dbbvwgi6and2fokqess5tojy2u	472	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	473	1	8	8	LS
work_dbbvwgi6and2fokqess5tojy2u	473	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	474	1	Pośpiech	pośpiech	NN
work_dbbvwgi6and2fokqess5tojy2u	474	2	E	E	NNP
work_dbbvwgi6and2fokqess5tojy2u	474	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	474	4	Draus	Draus	NNP
work_dbbvwgi6and2fokqess5tojy2u	474	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	474	6	Barini	Barini	NNP
work_dbbvwgi6and2fokqess5tojy2u	474	7	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	474	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	474	9	Kupiec	Kupiec	NNP
work_dbbvwgi6and2fokqess5tojy2u	474	10	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	474	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	474	12	Wojas	Wojas	NNP
work_dbbvwgi6and2fokqess5tojy2u	474	13	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	474	14	Pelc	Pelc	NNP
work_dbbvwgi6and2fokqess5tojy2u	474	15	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	474	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	474	17	Branicki	Branicki	NNP
work_dbbvwgi6and2fokqess5tojy2u	474	18	W.	W.	NNP
work_dbbvwgi6and2fokqess5tojy2u	474	19	Gene	Gene	NNP
work_dbbvwgi6and2fokqess5tojy2u	474	20	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	474	21	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	474	22	interactions	interaction	NNS
work_dbbvwgi6and2fokqess5tojy2u	474	23	contribute	contribute	VBP
work_dbbvwgi6and2fokqess5tojy2u	474	24	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	474	25	eye	eye	NN
work_dbbvwgi6and2fokqess5tojy2u	474	26	colour	colour	NN
work_dbbvwgi6and2fokqess5tojy2u	474	27	variation	variation	NN
work_dbbvwgi6and2fokqess5tojy2u	474	28	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	474	29	humans	human	NNS
work_dbbvwgi6and2fokqess5tojy2u	474	30	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	475	1	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	475	2	Hum	Hum	NNP
work_dbbvwgi6and2fokqess5tojy2u	475	3	Genet	Genet	NNP
work_dbbvwgi6and2fokqess5tojy2u	475	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	476	1	2011	2011	CD
work_dbbvwgi6and2fokqess5tojy2u	476	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	476	3	56	56	CD
work_dbbvwgi6and2fokqess5tojy2u	476	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	476	5	447	447	CD
work_dbbvwgi6and2fokqess5tojy2u	476	6	-	-	CD
work_dbbvwgi6and2fokqess5tojy2u	476	7	455	455	CD
work_dbbvwgi6and2fokqess5tojy2u	476	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	477	1	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	477	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	478	1	Mengel	Mengel	NNP
work_dbbvwgi6and2fokqess5tojy2u	478	2	-	-	:
work_dbbvwgi6and2fokqess5tojy2u	478	3	From	from	IN
work_dbbvwgi6and2fokqess5tojy2u	478	4	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	478	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	478	6	Børsting	Børsting	NNP
work_dbbvwgi6and2fokqess5tojy2u	478	7	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	478	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	478	9	Sanchez	Sanchez	NNP
work_dbbvwgi6and2fokqess5tojy2u	478	10	JJ	JJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	478	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	478	12	Eiberg	Eiberg	NNP
work_dbbvwgi6and2fokqess5tojy2u	478	13	H	H	NNP
work_dbbvwgi6and2fokqess5tojy2u	478	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	478	15	Morling	morle	VBG
work_dbbvwgi6and2fokqess5tojy2u	478	16	N.	N.	NNP
work_dbbvwgi6and2fokqess5tojy2u	478	17	Human	Human	NNP
work_dbbvwgi6and2fokqess5tojy2u	478	18	eye	eye	NN
work_dbbvwgi6and2fokqess5tojy2u	478	19	colour	colour	NN
work_dbbvwgi6and2fokqess5tojy2u	478	20	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	478	21	HERC2	herc2	NN
work_dbbvwgi6and2fokqess5tojy2u	478	22	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	478	23	OCA2	OCA2	NNP
work_dbbvwgi6and2fokqess5tojy2u	478	24	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	478	25	MATP	MATP	NNP
work_dbbvwgi6and2fokqess5tojy2u	478	26	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	479	1	Forensic	Forensic	NNP
work_dbbvwgi6and2fokqess5tojy2u	479	2	Sci	Sci	NNP
work_dbbvwgi6and2fokqess5tojy2u	479	3	Int	Int	NNP
work_dbbvwgi6and2fokqess5tojy2u	479	4	Genet	Genet	NNP
work_dbbvwgi6and2fokqess5tojy2u	479	5	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	480	1	2010	2010	CD
work_dbbvwgi6and2fokqess5tojy2u	480	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	480	3	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	480	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	480	5	323	323	CD
work_dbbvwgi6and2fokqess5tojy2u	480	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	480	7	328	328	CD
work_dbbvwgi6and2fokqess5tojy2u	480	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	481	1	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	481	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	482	1	White	white	JJ
work_dbbvwgi6and2fokqess5tojy2u	482	2	D	D	NNP
work_dbbvwgi6and2fokqess5tojy2u	482	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	482	4	Rabago	Rabago	NNP
work_dbbvwgi6and2fokqess5tojy2u	482	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	482	6	Smith	Smith	NNP
work_dbbvwgi6and2fokqess5tojy2u	482	7	M.	M.	NNP
work_dbbvwgi6and2fokqess5tojy2u	482	8	Genotype	Genotype	NNP
work_dbbvwgi6and2fokqess5tojy2u	482	9	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	482	10	phenotype	phenotype	NN
work_dbbvwgi6and2fokqess5tojy2u	482	11	associations	association	NNS
work_dbbvwgi6and2fokqess5tojy2u	482	12	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	482	13	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	482	14	eye	eye	NN
work_dbbvwgi6and2fokqess5tojy2u	482	15	color	color	NN
work_dbbvwgi6and2fokqess5tojy2u	482	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	483	1	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	483	2	Hum	Hum	NNP
work_dbbvwgi6and2fokqess5tojy2u	483	3	Genet	Genet	NNP
work_dbbvwgi6and2fokqess5tojy2u	483	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	484	1	2011	2011	CD
work_dbbvwgi6and2fokqess5tojy2u	484	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	484	3	56	56	CD
work_dbbvwgi6and2fokqess5tojy2u	484	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	484	5	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	484	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	484	7	7	7	CD
work_dbbvwgi6and2fokqess5tojy2u	484	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	485	1	11	11	CD
work_dbbvwgi6and2fokqess5tojy2u	485	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	486	1	Garcia	Garcia	NNP
work_dbbvwgi6and2fokqess5tojy2u	486	2	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	486	3	Gonzalo	Gonzalo	NNP
work_dbbvwgi6and2fokqess5tojy2u	486	4	FR	FR	NNP
work_dbbvwgi6and2fokqess5tojy2u	486	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	486	6	Rosa	Rosa	NNP
work_dbbvwgi6and2fokqess5tojy2u	486	7	JL	JL	NNP
work_dbbvwgi6and2fokqess5tojy2u	486	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	487	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	487	2	HERC	HERC	NNP
work_dbbvwgi6and2fokqess5tojy2u	487	3	proteins	protein	VBZ
work_dbbvwgi6and2fokqess5tojy2u	487	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	487	5	functional	functional	JJ
work_dbbvwgi6and2fokqess5tojy2u	487	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	487	7	evolutionary	evolutionary	JJ
work_dbbvwgi6and2fokqess5tojy2u	487	8	insights	insight	NNS
work_dbbvwgi6and2fokqess5tojy2u	487	9	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	488	1	Cell	Cell	NNP
work_dbbvwgi6and2fokqess5tojy2u	488	2	Mol	Mol	NNP
work_dbbvwgi6and2fokqess5tojy2u	488	3	Life	Life	NNP
work_dbbvwgi6and2fokqess5tojy2u	488	4	Sci	Sci	NNP
work_dbbvwgi6and2fokqess5tojy2u	488	5	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	489	1	2005	2005	CD
work_dbbvwgi6and2fokqess5tojy2u	489	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	489	3	62	62	CD
work_dbbvwgi6and2fokqess5tojy2u	489	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	489	5	1826	1826	CD
work_dbbvwgi6and2fokqess5tojy2u	489	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	489	7	38	38	CD
work_dbbvwgi6and2fokqess5tojy2u	489	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	490	1	12	12	CD
work_dbbvwgi6and2fokqess5tojy2u	490	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	491	1	Hadjebi	Hadjebi	NNP
work_dbbvwgi6and2fokqess5tojy2u	491	2	O	O	NNP
work_dbbvwgi6and2fokqess5tojy2u	491	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	491	4	Casas	Casas	NNP
work_dbbvwgi6and2fokqess5tojy2u	491	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	491	6	Terradellas	Terradellas	NNP
work_dbbvwgi6and2fokqess5tojy2u	491	7	E	E	NNP
work_dbbvwgi6and2fokqess5tojy2u	491	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	491	9	Garcia	Garcia	NNP
work_dbbvwgi6and2fokqess5tojy2u	491	10	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	491	11	Gonzalo	Gonzalo	NNP
work_dbbvwgi6and2fokqess5tojy2u	491	12	FR	FR	NNP
work_dbbvwgi6and2fokqess5tojy2u	491	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	491	14	Rosa	Rosa	NNP
work_dbbvwgi6and2fokqess5tojy2u	491	15	JL	JL	NNP
work_dbbvwgi6and2fokqess5tojy2u	491	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	492	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	492	2	RCC1	RCC1	NNP
work_dbbvwgi6and2fokqess5tojy2u	492	3	superfamily	superfamily	RB
work_dbbvwgi6and2fokqess5tojy2u	492	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	492	5	From	from	IN
work_dbbvwgi6and2fokqess5tojy2u	492	6	genes	gene	NNS
work_dbbvwgi6and2fokqess5tojy2u	492	7	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	492	8	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	492	9	function	function	VB
work_dbbvwgi6and2fokqess5tojy2u	492	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	492	11	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	492	12	disease	disease	VB
work_dbbvwgi6and2fokqess5tojy2u	492	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	493	1	Biochimica	Biochimica	NNP
work_dbbvwgi6and2fokqess5tojy2u	493	2	et	et	NNP
work_dbbvwgi6and2fokqess5tojy2u	493	3	Biophysica	Biophysica	NNP
work_dbbvwgi6and2fokqess5tojy2u	493	4	Acta	Acta	NNP
work_dbbvwgi6and2fokqess5tojy2u	493	5	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	494	1	2008	2008	CD
work_dbbvwgi6and2fokqess5tojy2u	494	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	494	3	1783	1783	CD
work_dbbvwgi6and2fokqess5tojy2u	494	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	494	5	1467-	1467-	CD
work_dbbvwgi6and2fokqess5tojy2u	494	6	1479	1479	CD
work_dbbvwgi6and2fokqess5tojy2u	494	7	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	495	1	13	13	CD
work_dbbvwgi6and2fokqess5tojy2u	495	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	496	1	Dastur	Dastur	NNP
work_dbbvwgi6and2fokqess5tojy2u	496	2	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	496	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	496	4	Beaudenon	Beaudenon	NNP
work_dbbvwgi6and2fokqess5tojy2u	496	5	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	496	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	496	7	Kelley	Kelley	NNP
work_dbbvwgi6and2fokqess5tojy2u	496	8	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	496	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	496	10	Krug	Krug	NNP
work_dbbvwgi6and2fokqess5tojy2u	496	11	RM	RM	NNP
work_dbbvwgi6and2fokqess5tojy2u	496	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	496	13	Huibregtse	Huibregtse	NNP
work_dbbvwgi6and2fokqess5tojy2u	496	14	JM	JM	NNP
work_dbbvwgi6and2fokqess5tojy2u	496	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	497	1	Herc5	Herc5	NNP
work_dbbvwgi6and2fokqess5tojy2u	497	2	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	497	3	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	497	4	interferon	interferon	NN
work_dbbvwgi6and2fokqess5tojy2u	497	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	497	6	induced	induce	VBN
work_dbbvwgi6and2fokqess5tojy2u	497	7	HECT	HECT	NNP
work_dbbvwgi6and2fokqess5tojy2u	497	8	E3	e3	NN
work_dbbvwgi6and2fokqess5tojy2u	497	9	enzyme	enzyme	NNS
work_dbbvwgi6and2fokqess5tojy2u	497	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	497	11	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	497	12	required	require	VBN
work_dbbvwgi6and2fokqess5tojy2u	497	13	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	497	14	conjugation	conjugation	NN
work_dbbvwgi6and2fokqess5tojy2u	497	15	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	497	16	ISG15	ISG15	NNP
work_dbbvwgi6and2fokqess5tojy2u	497	17	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	497	18	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	497	19	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	497	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	498	1	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	498	2	Biol	Biol	NNP
work_dbbvwgi6and2fokqess5tojy2u	498	3	Chem	Chem	NNP
work_dbbvwgi6and2fokqess5tojy2u	498	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	499	1	2006	2006	CD
work_dbbvwgi6and2fokqess5tojy2u	499	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	499	3	281	281	CD
work_dbbvwgi6and2fokqess5tojy2u	499	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	499	5	4334	4334	CD
work_dbbvwgi6and2fokqess5tojy2u	499	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	499	7	4338	4338	CD
work_dbbvwgi6and2fokqess5tojy2u	499	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	500	1	14	14	CD
work_dbbvwgi6and2fokqess5tojy2u	500	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	501	1	Kroismayr	Kroismayr	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	2	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	501	4	Baranyi	Baranyi	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	5	U	U	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	501	7	Stehlik	Stehlik	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	8	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	501	10	Dorfleutner	Dorfleutner	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	11	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	501	13	Binder	Binder	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	14	BR	BR	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	501	16	Lipp	Lipp	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	17	J.	J.	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	18	HERC5	HERC5	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	501	20	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	501	21	HECT	HECT	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	22	E3	E3	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	23	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	501	24	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	501	25	tightly	tightly	RB
work_dbbvwgi6and2fokqess5tojy2u	501	26	regulated	regulate	VBN
work_dbbvwgi6and2fokqess5tojy2u	501	27	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	501	28	LPS	LPS	NNP
work_dbbvwgi6and2fokqess5tojy2u	501	29	activated	activate	VBD
work_dbbvwgi6and2fokqess5tojy2u	501	30	endothelial	endothelial	JJ
work_dbbvwgi6and2fokqess5tojy2u	501	31	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	501	32	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	502	1	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	502	2	Cell	Cell	NNP
work_dbbvwgi6and2fokqess5tojy2u	502	3	Sci	Sci	NNP
work_dbbvwgi6and2fokqess5tojy2u	502	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	503	1	2004	2004	CD
work_dbbvwgi6and2fokqess5tojy2u	503	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	503	3	117	117	CD
work_dbbvwgi6and2fokqess5tojy2u	503	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	503	5	4749	4749	CD
work_dbbvwgi6and2fokqess5tojy2u	503	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	503	7	4756	4756	CD
work_dbbvwgi6and2fokqess5tojy2u	503	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	504	1	15	15	CD
work_dbbvwgi6and2fokqess5tojy2u	504	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	505	1	Hochrainer	Hochrainer	NNP
work_dbbvwgi6and2fokqess5tojy2u	505	2	K	K	NNP
work_dbbvwgi6and2fokqess5tojy2u	505	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	505	4	Kroismayr	Kroismayr	NNP
work_dbbvwgi6and2fokqess5tojy2u	505	5	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	505	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	505	7	Baranyi	Baranyi	NNP
work_dbbvwgi6and2fokqess5tojy2u	505	8	U	U	NNP
work_dbbvwgi6and2fokqess5tojy2u	505	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	505	10	Binder	Binder	NNP
work_dbbvwgi6and2fokqess5tojy2u	505	11	BR	BR	NNP
work_dbbvwgi6and2fokqess5tojy2u	505	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	505	13	Lipp	Lipp	NNP
work_dbbvwgi6and2fokqess5tojy2u	505	14	J.	J.	NNP
work_dbbvwgi6and2fokqess5tojy2u	506	1	Highly	highly	RB
work_dbbvwgi6and2fokqess5tojy2u	506	2	homologous	homologous	JJ
work_dbbvwgi6and2fokqess5tojy2u	506	3	HERC	HERC	NNP
work_dbbvwgi6and2fokqess5tojy2u	506	4	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	506	5	localize	localize	VBP
work_dbbvwgi6and2fokqess5tojy2u	506	6	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	506	7	endosomes	endosome	NNS
work_dbbvwgi6and2fokqess5tojy2u	506	8	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	506	9	exhibit	exhibit	VB
work_dbbvwgi6and2fokqess5tojy2u	506	10	specific	specific	JJ
work_dbbvwgi6and2fokqess5tojy2u	506	11	interactions	interaction	NNS
work_dbbvwgi6and2fokqess5tojy2u	506	12	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	506	13	hPLIC	hPLIC	NNS
work_dbbvwgi6and2fokqess5tojy2u	506	14	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	506	15	Nm23B.	nm23b.	CD
work_dbbvwgi6and2fokqess5tojy2u	507	1	Cell	Cell	NNP
work_dbbvwgi6and2fokqess5tojy2u	507	2	Mol	Mol	NNP
work_dbbvwgi6and2fokqess5tojy2u	507	3	Life	Life	NNP
work_dbbvwgi6and2fokqess5tojy2u	507	4	Sci	Sci	NNP
work_dbbvwgi6and2fokqess5tojy2u	507	5	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	508	1	2008	2008	CD
work_dbbvwgi6and2fokqess5tojy2u	508	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	508	3	65	65	CD
work_dbbvwgi6and2fokqess5tojy2u	508	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	508	5	2105	2105	CD
work_dbbvwgi6and2fokqess5tojy2u	508	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	508	7	2117	2117	CD
work_dbbvwgi6and2fokqess5tojy2u	508	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	509	1	16	16	CD
work_dbbvwgi6and2fokqess5tojy2u	509	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	510	1	Diouf	Diouf	NNS
work_dbbvwgi6and2fokqess5tojy2u	510	2	B	B	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	510	4	Cheng	Cheng	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	5	Q	Q	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	510	7	Krynetskaia	Krynetskaia	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	8	NF	NF	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	510	10	Yang	Yang	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	11	W	W	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	510	13	Cheok	Cheok	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	14	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	510	16	Pei	Pei	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	17	D	D	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	510	19	Fan	Fan	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	20	Y	Y	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	510	22	Cheng	Cheng	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	23	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	510	25	Krynetskiy	Krynetskiy	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	26	EY	EY	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	27	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	510	28	Geng	Geng	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	29	H	H	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	30	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	510	31	Chen	Chen	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	32	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	33	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	510	34	Thierfelder	Thierfelder	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	35	WE	WE	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	36	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	510	37	Mullighan	Mullighan	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	38	CG	CG	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	39	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	510	40	et	et	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	41	al	al	NNP
work_dbbvwgi6and2fokqess5tojy2u	510	42	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	511	1	Somatic	somatic	JJ
work_dbbvwgi6and2fokqess5tojy2u	511	2	deletions	deletion	NNS
work_dbbvwgi6and2fokqess5tojy2u	511	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	511	4	genes	gene	NNS
work_dbbvwgi6and2fokqess5tojy2u	511	5	regulating	regulate	VBG
work_dbbvwgi6and2fokqess5tojy2u	511	6	MSH2	MSH2	NNP
work_dbbvwgi6and2fokqess5tojy2u	511	7	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	511	8	stability	stability	NN
work_dbbvwgi6and2fokqess5tojy2u	511	9	cause	cause	IN
work_dbbvwgi6and2fokqess5tojy2u	511	10	DNA	dna	NN
work_dbbvwgi6and2fokqess5tojy2u	511	11	mismatch	mismatch	NN
work_dbbvwgi6and2fokqess5tojy2u	511	12	repair	repair	NN
work_dbbvwgi6and2fokqess5tojy2u	511	13	deficiency	deficiency	NN
work_dbbvwgi6and2fokqess5tojy2u	511	14	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	511	15	drug	drug	NN
work_dbbvwgi6and2fokqess5tojy2u	511	16	resistance	resistance	NN
work_dbbvwgi6and2fokqess5tojy2u	511	17	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	511	18	human	human	JJ
work_dbbvwgi6and2fokqess5tojy2u	511	19	leukemia	leukemia	NN
work_dbbvwgi6and2fokqess5tojy2u	511	20	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	511	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	512	1	Nat	Nat	NNP
work_dbbvwgi6and2fokqess5tojy2u	512	2	Med	Med	NNP
work_dbbvwgi6and2fokqess5tojy2u	512	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	513	1	2011	2011	CD
work_dbbvwgi6and2fokqess5tojy2u	513	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	513	3	17	17	CD
work_dbbvwgi6and2fokqess5tojy2u	513	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	513	5	1298	1298	CD
work_dbbvwgi6and2fokqess5tojy2u	513	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	513	7	1303	1303	CD
work_dbbvwgi6and2fokqess5tojy2u	513	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	514	1	17	17	CD
work_dbbvwgi6and2fokqess5tojy2u	514	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	515	1	Bekker	Bekker	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	2	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	515	3	Jensen	Jensen	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	4	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	515	6	Rendtlew	Rendtlew	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	7	Danielsen	Danielsen	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	8	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	515	10	Fugger	Fugger	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	11	K	K	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	515	13	Gromova	Gromova	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	14	I	I	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	515	16	Nerstedt	Nerstedt	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	17	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	515	19	Lukas	Lukas	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	20	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	515	22	Bartek	Bartek	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	23	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	515	25	Lukas	Lukas	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	26	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	27	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	515	28	Mailand	Mailand	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	29	N.	N.	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	30	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	515	31	coordinates	coordinate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	515	32	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	515	33	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	515	34	dependent	dependent	JJ
work_dbbvwgi6and2fokqess5tojy2u	515	35	assembly	assembly	NN
work_dbbvwgi6and2fokqess5tojy2u	515	36	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	515	37	DNA	dna	NN
work_dbbvwgi6and2fokqess5tojy2u	515	38	repair	repair	NN
work_dbbvwgi6and2fokqess5tojy2u	515	39	factors	factor	NNS
work_dbbvwgi6and2fokqess5tojy2u	515	40	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	515	41	damaged	damaged	JJ
work_dbbvwgi6and2fokqess5tojy2u	515	42	chromosomes	chromosome	NNS
work_dbbvwgi6and2fokqess5tojy2u	515	43	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	516	1	Nat	Nat	NNP
work_dbbvwgi6and2fokqess5tojy2u	516	2	Cell	Cell	NNP
work_dbbvwgi6and2fokqess5tojy2u	516	3	Biol	Biol	NNP
work_dbbvwgi6and2fokqess5tojy2u	516	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	517	1	2010	2010	CD
work_dbbvwgi6and2fokqess5tojy2u	517	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	517	3	12	12	CD
work_dbbvwgi6and2fokqess5tojy2u	517	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	517	5	12	12	CD
work_dbbvwgi6and2fokqess5tojy2u	517	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	517	7	80	80	CD
work_dbbvwgi6and2fokqess5tojy2u	517	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	518	1	18	18	CD
work_dbbvwgi6and2fokqess5tojy2u	518	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	519	1	Yoo	Yoo	NNP
work_dbbvwgi6and2fokqess5tojy2u	519	2	NJ	NJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	519	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	519	4	Park	Park	NNP
work_dbbvwgi6and2fokqess5tojy2u	519	5	SW	SW	NNP
work_dbbvwgi6and2fokqess5tojy2u	519	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	519	7	Lee	Lee	NNP
work_dbbvwgi6and2fokqess5tojy2u	519	8	SH	SH	NNP
work_dbbvwgi6and2fokqess5tojy2u	519	9	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	520	1	Frameshift	frameshift	NN
work_dbbvwgi6and2fokqess5tojy2u	520	2	mutations	mutation	NNS
work_dbbvwgi6and2fokqess5tojy2u	520	3	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	520	4	ubiquitination	ubiquitination	NN
work_dbbvwgi6and2fokqess5tojy2u	520	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	520	6	related	relate	VBN
work_dbbvwgi6and2fokqess5tojy2u	520	7	genes	gene	NNS
work_dbbvwgi6and2fokqess5tojy2u	520	8	HERC2	herc2	VBP
work_dbbvwgi6and2fokqess5tojy2u	520	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	520	10	HERC3	herc3	ADD
work_dbbvwgi6and2fokqess5tojy2u	520	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	520	12	TRIP12	trip12	UH
work_dbbvwgi6and2fokqess5tojy2u	520	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	520	14	UBE2Q1	UBE2Q1	NNP
work_dbbvwgi6and2fokqess5tojy2u	520	15	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	520	16	UBE4B	UBE4B	NNP
work_dbbvwgi6and2fokqess5tojy2u	520	17	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	520	18	gastric	gastric	JJ
work_dbbvwgi6and2fokqess5tojy2u	520	19	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	520	20	colorectal	colorectal	JJ
work_dbbvwgi6and2fokqess5tojy2u	520	21	carcinomas	carcinoma	NNS
work_dbbvwgi6and2fokqess5tojy2u	520	22	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	520	23	microsatellite	microsatellite	JJ
work_dbbvwgi6and2fokqess5tojy2u	520	24	instability	instability	NN
work_dbbvwgi6and2fokqess5tojy2u	520	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	521	1	Pathology	pathology	NN
work_dbbvwgi6and2fokqess5tojy2u	521	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	522	1	2011	2011	CD
work_dbbvwgi6and2fokqess5tojy2u	522	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	522	3	43	43	CD
work_dbbvwgi6and2fokqess5tojy2u	522	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	522	5	753-	753-	CD
work_dbbvwgi6and2fokqess5tojy2u	522	6	755	755	CD
work_dbbvwgi6and2fokqess5tojy2u	522	7	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	523	1	19	19	CD
work_dbbvwgi6and2fokqess5tojy2u	523	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	524	1	Zhou	Zhou	NNP
work_dbbvwgi6and2fokqess5tojy2u	524	2	H	h	NN
work_dbbvwgi6and2fokqess5tojy2u	524	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	524	4	Shi	Shi	NNP
work_dbbvwgi6and2fokqess5tojy2u	524	5	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	524	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	524	7	Wei	Wei	NNP
work_dbbvwgi6and2fokqess5tojy2u	524	8	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	524	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	524	10	Zheng	Zheng	NNP
work_dbbvwgi6and2fokqess5tojy2u	524	11	W	W	NNP
work_dbbvwgi6and2fokqess5tojy2u	524	12	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	524	13	L	L	NNP
work_dbbvwgi6and2fokqess5tojy2u	524	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	524	15	Zhou	Zhou	NNP
work_dbbvwgi6and2fokqess5tojy2u	524	16	JY	JY	NNP
work_dbbvwgi6and2fokqess5tojy2u	524	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	524	18	Ma	Ma	NNP
work_dbbvwgi6and2fokqess5tojy2u	524	19	WL	WL	NNP
work_dbbvwgi6and2fokqess5tojy2u	524	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	525	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	525	2	expression	expression	NN
work_dbbvwgi6and2fokqess5tojy2u	525	3	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	525	4	clinical	clinical	JJ
work_dbbvwgi6and2fokqess5tojy2u	525	5	significance	significance	NN
work_dbbvwgi6and2fokqess5tojy2u	525	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	525	7	HERC4	herc4	NN
work_dbbvwgi6and2fokqess5tojy2u	525	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	525	9	breast	breast	NN
work_dbbvwgi6and2fokqess5tojy2u	525	10	cancer	cancer	NN
work_dbbvwgi6and2fokqess5tojy2u	525	11	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	526	1	Cancer	Cancer	NNP
work_dbbvwgi6and2fokqess5tojy2u	526	2	Cell	Cell	NNP
work_dbbvwgi6and2fokqess5tojy2u	526	3	Int	Int	NNP
work_dbbvwgi6and2fokqess5tojy2u	526	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	527	1	2013	2013	CD
work_dbbvwgi6and2fokqess5tojy2u	527	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	527	3	13	13	CD
work_dbbvwgi6and2fokqess5tojy2u	527	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	527	5	113	113	CD
work_dbbvwgi6and2fokqess5tojy2u	527	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	528	1	20	20	CD
work_dbbvwgi6and2fokqess5tojy2u	528	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	529	1	Sánchez	sánchez	NN
work_dbbvwgi6and2fokqess5tojy2u	529	2	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	529	3	Tena	Tena	NNP
work_dbbvwgi6and2fokqess5tojy2u	529	4	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	529	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	529	6	Cubillos	Cubillos	NNP
work_dbbvwgi6and2fokqess5tojy2u	529	7	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	529	8	Rojas	Rojas	NNP
work_dbbvwgi6and2fokqess5tojy2u	529	9	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	529	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	529	11	Schneider	Schneider	NNP
work_dbbvwgi6and2fokqess5tojy2u	529	12	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	529	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	529	14	Rosa	Rosa	NNP
work_dbbvwgi6and2fokqess5tojy2u	529	15	JL	JL	NNP
work_dbbvwgi6and2fokqess5tojy2u	529	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	530	1	Functional	functional	JJ
work_dbbvwgi6and2fokqess5tojy2u	530	2	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	530	3	pathological	pathological	JJ
work_dbbvwgi6and2fokqess5tojy2u	530	4	relevance	relevance	NN
work_dbbvwgi6and2fokqess5tojy2u	530	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	530	6	HERC	HERC	NNP
work_dbbvwgi6and2fokqess5tojy2u	530	7	family	family	NN
work_dbbvwgi6and2fokqess5tojy2u	530	8	proteins	protein	VBZ
work_dbbvwgi6and2fokqess5tojy2u	530	9	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	530	10	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	530	11	decade	decade	NN
work_dbbvwgi6and2fokqess5tojy2u	530	12	later	later	RB
work_dbbvwgi6and2fokqess5tojy2u	530	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	531	1	Cell	Cell	NNP
work_dbbvwgi6and2fokqess5tojy2u	531	2	Mol	Mol	NNP
work_dbbvwgi6and2fokqess5tojy2u	531	3	Life	Life	NNP
work_dbbvwgi6and2fokqess5tojy2u	531	4	Sci	Sci	NNP
work_dbbvwgi6and2fokqess5tojy2u	531	5	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	532	1	2016	2016	CD
work_dbbvwgi6and2fokqess5tojy2u	532	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	532	3	73	73	CD
work_dbbvwgi6and2fokqess5tojy2u	532	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	532	5	1955-	1955-	CD
work_dbbvwgi6and2fokqess5tojy2u	532	6	1968	1968	CD
work_dbbvwgi6and2fokqess5tojy2u	532	7	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	533	1	21	21	CD
work_dbbvwgi6and2fokqess5tojy2u	533	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	534	1	Kang	Kang	NNP
work_dbbvwgi6and2fokqess5tojy2u	534	2	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	534	3	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	534	4	H	H	NNP
work_dbbvwgi6and2fokqess5tojy2u	534	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	534	6	Lindsey	Lindsey	NNP
work_dbbvwgi6and2fokqess5tojy2u	534	7	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	534	8	Boltz	Boltz	NNP
work_dbbvwgi6and2fokqess5tojy2u	534	9	L	L	NNP
work_dbbvwgi6and2fokqess5tojy2u	534	10	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	534	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	534	12	Reardon	Reardon	NNP
work_dbbvwgi6and2fokqess5tojy2u	534	13	JT	JT	NNP
work_dbbvwgi6and2fokqess5tojy2u	534	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	534	15	Sancar	sancar	NN
work_dbbvwgi6and2fokqess5tojy2u	534	16	A.	a.	NN
work_dbbvwgi6and2fokqess5tojy2u	534	17	Circadian	circadian	JJ
work_dbbvwgi6and2fokqess5tojy2u	534	18	control	control	NN
work_dbbvwgi6and2fokqess5tojy2u	534	19	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	534	20	XPA	xpa	NN
work_dbbvwgi6and2fokqess5tojy2u	534	21	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	534	22	excision	excision	NN
work_dbbvwgi6and2fokqess5tojy2u	534	23	repair	repair	NN
work_dbbvwgi6and2fokqess5tojy2u	534	24	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	534	25	cisplatin-	cisplatin-	JJ
work_dbbvwgi6and2fokqess5tojy2u	534	26	DNA	dna	NN
work_dbbvwgi6and2fokqess5tojy2u	534	27	damage	damage	NN
work_dbbvwgi6and2fokqess5tojy2u	534	28	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	534	29	cryptochrome	cryptochrome	NN
work_dbbvwgi6and2fokqess5tojy2u	534	30	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	534	31	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	534	32	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	534	33	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	534	34	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	535	1	Proc	Proc	NNP
work_dbbvwgi6and2fokqess5tojy2u	535	2	Natl	Natl	NNP
work_dbbvwgi6and2fokqess5tojy2u	535	3	Acad	Acad	NNP
work_dbbvwgi6and2fokqess5tojy2u	535	4	Sci	Sci	NNP
work_dbbvwgi6and2fokqess5tojy2u	535	5	U	U	NNP
work_dbbvwgi6and2fokqess5tojy2u	535	6	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	535	7	A.	a.	NN
work_dbbvwgi6and2fokqess5tojy2u	536	1	2010	2010	CD
work_dbbvwgi6and2fokqess5tojy2u	536	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	536	3	107	107	CD
work_dbbvwgi6and2fokqess5tojy2u	536	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	536	5	4890	4890	CD
work_dbbvwgi6and2fokqess5tojy2u	536	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	536	7	4895	4895	CD
work_dbbvwgi6and2fokqess5tojy2u	536	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	537	1	22	22	CD
work_dbbvwgi6and2fokqess5tojy2u	537	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	538	1	Wu	Wu	NNP
work_dbbvwgi6and2fokqess5tojy2u	538	2	W	W	NNP
work_dbbvwgi6and2fokqess5tojy2u	538	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	538	4	Sato	Sato	NNP
work_dbbvwgi6and2fokqess5tojy2u	538	5	K	K	NNP
work_dbbvwgi6and2fokqess5tojy2u	538	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	538	7	Koike	Koike	NNP
work_dbbvwgi6and2fokqess5tojy2u	538	8	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	538	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	538	10	Nishikawa	Nishikawa	NNP
work_dbbvwgi6and2fokqess5tojy2u	538	11	H	H	NNP
work_dbbvwgi6and2fokqess5tojy2u	538	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	538	13	Koizumi	Koizumi	NNP
work_dbbvwgi6and2fokqess5tojy2u	538	14	H	H	NNP
work_dbbvwgi6and2fokqess5tojy2u	538	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	538	16	Venkitaraman	Venkitaraman	NNP
work_dbbvwgi6and2fokqess5tojy2u	538	17	AR	AR	NNP
work_dbbvwgi6and2fokqess5tojy2u	538	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	538	19	Ohta	Ohta	NNP
work_dbbvwgi6and2fokqess5tojy2u	538	20	T.	T.	NNP
work_dbbvwgi6and2fokqess5tojy2u	538	21	HERC2	herc2	NN
work_dbbvwgi6and2fokqess5tojy2u	538	22	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	538	23	an	an	DT
work_dbbvwgi6and2fokqess5tojy2u	538	24	E3	e3	JJ
work_dbbvwgi6and2fokqess5tojy2u	538	25	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	538	26	that	that	WDT
work_dbbvwgi6and2fokqess5tojy2u	538	27	targets	target	VBZ
work_dbbvwgi6and2fokqess5tojy2u	538	28	BRCA1	brca1	NN
work_dbbvwgi6and2fokqess5tojy2u	538	29	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	538	30	degradation	degradation	NN
work_dbbvwgi6and2fokqess5tojy2u	538	31	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	539	1	Cancer	cancer	NN
work_dbbvwgi6and2fokqess5tojy2u	539	2	Res	Res	NNP
work_dbbvwgi6and2fokqess5tojy2u	539	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	540	1	2010	2010	CD
work_dbbvwgi6and2fokqess5tojy2u	540	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	540	3	70	70	CD
work_dbbvwgi6and2fokqess5tojy2u	540	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	540	5	6384	6384	CD
work_dbbvwgi6and2fokqess5tojy2u	540	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	540	7	6392	6392	CD
work_dbbvwgi6and2fokqess5tojy2u	540	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	541	1	23	23	CD
work_dbbvwgi6and2fokqess5tojy2u	541	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	542	1	Oestergaard	Oestergaard	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	2	VH	VH	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	542	4	Pentzold	Pentzold	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	5	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	542	7	Pedersen	Pedersen	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	8	RT	RT	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	542	10	Iosif	Iosif	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	11	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	542	13	Alpi	Alpi	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	14	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	542	16	Bekker	Bekker	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	17	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	542	18	Jensen	Jensen	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	19	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	542	21	Mailand	Mailand	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	22	N	N	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	542	24	Lisby	Lisby	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	25	M.	M.	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	26	RNF8	RNF8	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	27	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	542	28	RNF168	RNF168	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	29	but	but	CC
work_dbbvwgi6and2fokqess5tojy2u	542	30	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	542	31	HERC2	HERC2	NNS
work_dbbvwgi6and2fokqess5tojy2u	542	32	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	542	33	required	require	VBN
work_dbbvwgi6and2fokqess5tojy2u	542	34	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	542	35	DNA	dna	NN
work_dbbvwgi6and2fokqess5tojy2u	542	36	damage	damage	NN
work_dbbvwgi6and2fokqess5tojy2u	542	37	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	542	38	induced	induce	VBN
work_dbbvwgi6and2fokqess5tojy2u	542	39	ubiquitylation	ubiquitylation	NN
work_dbbvwgi6and2fokqess5tojy2u	542	40	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	542	41	chicken	chicken	NN
work_dbbvwgi6and2fokqess5tojy2u	542	42	DT40	DT40	NNP
work_dbbvwgi6and2fokqess5tojy2u	542	43	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	542	44	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	543	1	DNA	DNA	NNP
work_dbbvwgi6and2fokqess5tojy2u	543	2	Repair	Repair	NNP
work_dbbvwgi6and2fokqess5tojy2u	543	3	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	543	4	Amst	Amst	NNP
work_dbbvwgi6and2fokqess5tojy2u	543	5	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	543	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	544	1	2012	2012	CD
work_dbbvwgi6and2fokqess5tojy2u	544	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	544	3	11	11	CD
work_dbbvwgi6and2fokqess5tojy2u	544	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	544	5	892	892	CD
work_dbbvwgi6and2fokqess5tojy2u	544	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	544	7	905	905	CD
work_dbbvwgi6and2fokqess5tojy2u	544	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	545	1	24	24	CD
work_dbbvwgi6and2fokqess5tojy2u	545	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	546	1	Al	Al	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	2	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	546	3	Hakim	Hakim	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	4	AK	AK	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	546	6	Bashkurov	Bashkurov	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	7	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	546	9	Gingras	Gingras	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	10	AC	AC	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	546	12	Durocher	Durocher	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	13	D	D	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	546	15	Pelletier	Pelletier	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	16	L.	L.	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	17	Interaction	Interaction	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	18	Proteomics	Proteomics	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	19	Identify	Identify	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	20	NEURL4	neurl4	NN
work_dbbvwgi6and2fokqess5tojy2u	546	21	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	546	22	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	546	23	HECT	HECT	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	24	E3	E3	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	25	Ligase	Ligase	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	26	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	27	as	as	IN
work_dbbvwgi6and2fokqess5tojy2u	546	28	Novel	Novel	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	29	Modulators	Modulators	NNPS
work_dbbvwgi6and2fokqess5tojy2u	546	30	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	546	31	Centrosome	Centrosome	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	32	Architecture	Architecture	NNP
work_dbbvwgi6and2fokqess5tojy2u	546	33	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	547	1	Mol	Mol	NNP
work_dbbvwgi6and2fokqess5tojy2u	547	2	Cell	Cell	NNP
work_dbbvwgi6and2fokqess5tojy2u	547	3	Proteomics	Proteomics	NNP
work_dbbvwgi6and2fokqess5tojy2u	547	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	548	1	2012	2012	CD
work_dbbvwgi6and2fokqess5tojy2u	548	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	548	3	11	11	CD
work_dbbvwgi6and2fokqess5tojy2u	548	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	548	5	M111.014233	m111.014233	CD
work_dbbvwgi6and2fokqess5tojy2u	548	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	549	1	25	25	CD
work_dbbvwgi6and2fokqess5tojy2u	549	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	550	1	Chan	Chan	NNP
work_dbbvwgi6and2fokqess5tojy2u	550	2	NC	NC	NNP
work_dbbvwgi6and2fokqess5tojy2u	550	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	550	4	Den	Den	NNP
work_dbbvwgi6and2fokqess5tojy2u	550	5	Besten	Besten	NNP
work_dbbvwgi6and2fokqess5tojy2u	550	6	W	W	NNP
work_dbbvwgi6and2fokqess5tojy2u	550	7	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	550	8	Sweredoski	Sweredoski	NNP
work_dbbvwgi6and2fokqess5tojy2u	550	9	MJ	MJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	550	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	550	11	Hess	Hess	NNP
work_dbbvwgi6and2fokqess5tojy2u	550	12	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	550	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	550	14	Deshaies	Deshaies	NNP
work_dbbvwgi6and2fokqess5tojy2u	550	15	RJ	RJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	550	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	550	17	Chan	Chan	NNP
work_dbbvwgi6and2fokqess5tojy2u	550	18	DC	DC	NNP
work_dbbvwgi6and2fokqess5tojy2u	550	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	551	1	Degradation	degradation	NN
work_dbbvwgi6and2fokqess5tojy2u	551	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	551	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	551	4	deubiquitinating	deubiquitinate	VBG
work_dbbvwgi6and2fokqess5tojy2u	551	5	enzyme	enzyme	NNS
work_dbbvwgi6and2fokqess5tojy2u	551	6	USP33	USP33	NNP
work_dbbvwgi6and2fokqess5tojy2u	551	7	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	551	8	mediated	mediate	VBN
work_dbbvwgi6and2fokqess5tojy2u	551	9	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	551	10	p97	p97	NN
work_dbbvwgi6and2fokqess5tojy2u	551	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	551	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	551	13	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	551	14	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	551	15	HERC2	herc2	NN
work_dbbvwgi6and2fokqess5tojy2u	551	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	552	1	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	552	2	Biol	Biol	NNP
work_dbbvwgi6and2fokqess5tojy2u	552	3	Chem	Chem	NNP
work_dbbvwgi6and2fokqess5tojy2u	552	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	553	1	2014	2014	CD
work_dbbvwgi6and2fokqess5tojy2u	553	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	553	3	289	289	CD
work_dbbvwgi6and2fokqess5tojy2u	553	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	553	5	19789	19789	CD
work_dbbvwgi6and2fokqess5tojy2u	553	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	553	7	19798	19798	CD
work_dbbvwgi6and2fokqess5tojy2u	553	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	554	1	26	26	CD
work_dbbvwgi6and2fokqess5tojy2u	554	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	555	1	Moroishi	Moroishi	NNP
work_dbbvwgi6and2fokqess5tojy2u	555	2	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	555	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	555	4	Yamauchi	Yamauchi	NNP
work_dbbvwgi6and2fokqess5tojy2u	555	5	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	555	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	555	7	Nishiyama	Nishiyama	NNP
work_dbbvwgi6and2fokqess5tojy2u	555	8	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	555	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	555	10	Nakayama	Nakayama	NNP
work_dbbvwgi6and2fokqess5tojy2u	555	11	KI	KI	NNP
work_dbbvwgi6and2fokqess5tojy2u	555	12	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	556	1	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	556	2	targets	target	VBZ
work_dbbvwgi6and2fokqess5tojy2u	556	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	556	4	iron	iron	NN
work_dbbvwgi6and2fokqess5tojy2u	556	5	regulator	regulator	NN
work_dbbvwgi6and2fokqess5tojy2u	556	6	FBXL5	FBXL5	NNS
work_dbbvwgi6and2fokqess5tojy2u	556	7	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	556	8	degradation	degradation	NN
work_dbbvwgi6and2fokqess5tojy2u	556	9	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	556	10	modulates	modulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	556	11	iron	iron	NN
work_dbbvwgi6and2fokqess5tojy2u	556	12	metabolism	metabolism	NN
work_dbbvwgi6and2fokqess5tojy2u	556	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	557	1	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	557	2	Biol	Biol	NNP
work_dbbvwgi6and2fokqess5tojy2u	557	3	Chem	Chem	NNP
work_dbbvwgi6and2fokqess5tojy2u	557	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	558	1	2014	2014	CD
work_dbbvwgi6and2fokqess5tojy2u	558	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	558	3	289	289	CD
work_dbbvwgi6and2fokqess5tojy2u	558	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	558	5	16430	16430	CD
work_dbbvwgi6and2fokqess5tojy2u	558	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	558	7	16441	16441	CD
work_dbbvwgi6and2fokqess5tojy2u	558	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	559	1	27	27	CD
work_dbbvwgi6and2fokqess5tojy2u	559	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	560	1	Brady	Brady	NNP
work_dbbvwgi6and2fokqess5tojy2u	560	2	CA	CA	NNP
work_dbbvwgi6and2fokqess5tojy2u	560	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	560	4	Attardi	Attardi	NNP
work_dbbvwgi6and2fokqess5tojy2u	560	5	LD	LD	NNP
work_dbbvwgi6and2fokqess5tojy2u	560	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	561	1	P53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	561	2	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	561	3	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	561	4	Glance	Glance	NNP
work_dbbvwgi6and2fokqess5tojy2u	561	5	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	562	1	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	562	2	Cell	Cell	NNP
work_dbbvwgi6and2fokqess5tojy2u	562	3	Sci	Sci	NNP
work_dbbvwgi6and2fokqess5tojy2u	562	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	563	1	2010	2010	CD
work_dbbvwgi6and2fokqess5tojy2u	563	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	563	3	123	123	CD
work_dbbvwgi6and2fokqess5tojy2u	563	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	563	5	2527	2527	CD
work_dbbvwgi6and2fokqess5tojy2u	563	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	563	7	2532	2532	CD
work_dbbvwgi6and2fokqess5tojy2u	563	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	564	1	28	28	CD
work_dbbvwgi6and2fokqess5tojy2u	564	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	565	1	Kruse	Kruse	NNP
work_dbbvwgi6and2fokqess5tojy2u	565	2	JP	JP	NNP
work_dbbvwgi6and2fokqess5tojy2u	565	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	565	4	Gu	Gu	NNP
work_dbbvwgi6and2fokqess5tojy2u	565	5	W.	W.	NNP
work_dbbvwgi6and2fokqess5tojy2u	565	6	Modes	Modes	NNP
work_dbbvwgi6and2fokqess5tojy2u	565	7	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	565	8	p53	p53	CD
work_dbbvwgi6and2fokqess5tojy2u	565	9	Regulation	regulation	NN
work_dbbvwgi6and2fokqess5tojy2u	565	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	566	1	Cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	566	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	567	1	2009	2009	CD
work_dbbvwgi6and2fokqess5tojy2u	567	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	567	3	137	137	CD
work_dbbvwgi6and2fokqess5tojy2u	567	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	567	5	609	609	CD
work_dbbvwgi6and2fokqess5tojy2u	567	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	567	7	622	622	CD
work_dbbvwgi6and2fokqess5tojy2u	567	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	568	1	29	29	CD
work_dbbvwgi6and2fokqess5tojy2u	568	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	569	1	Itahana	Itahana	NNP
work_dbbvwgi6and2fokqess5tojy2u	569	2	Y	Y	NNP
work_dbbvwgi6and2fokqess5tojy2u	569	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	569	4	Ke	Ke	NNP
work_dbbvwgi6and2fokqess5tojy2u	569	5	H	H	NNP
work_dbbvwgi6and2fokqess5tojy2u	569	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	569	7	Zhang	Zhang	NNP
work_dbbvwgi6and2fokqess5tojy2u	569	8	Y.	Y.	NNP
work_dbbvwgi6and2fokqess5tojy2u	569	9	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	569	10	Oligomerization	Oligomerization	NNP
work_dbbvwgi6and2fokqess5tojy2u	569	11	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	569	12	essential	essential	JJ
work_dbbvwgi6and2fokqess5tojy2u	569	13	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	569	14	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	569	15	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	569	16	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	569	17	terminal	terminal	JJ
work_dbbvwgi6and2fokqess5tojy2u	569	18	lysine	lysine	JJ
work_dbbvwgi6and2fokqess5tojy2u	569	19	acetylation	acetylation	NN
work_dbbvwgi6and2fokqess5tojy2u	569	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	570	1	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	570	2	Biol	Biol	NNP
work_dbbvwgi6and2fokqess5tojy2u	570	3	Chem	Chem	NNP
work_dbbvwgi6and2fokqess5tojy2u	570	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	571	1	2009	2009	CD
work_dbbvwgi6and2fokqess5tojy2u	571	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	571	3	284	284	CD
work_dbbvwgi6and2fokqess5tojy2u	571	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	571	5	5158	5158	CD
work_dbbvwgi6and2fokqess5tojy2u	571	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	571	7	5164	5164	CD
work_dbbvwgi6and2fokqess5tojy2u	571	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	572	1	30	30	CD
work_dbbvwgi6and2fokqess5tojy2u	572	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	573	1	Davison	Davison	NNP
work_dbbvwgi6and2fokqess5tojy2u	573	2	TS	TS	NNP
work_dbbvwgi6and2fokqess5tojy2u	573	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	573	4	Yin	Yin	NNP
work_dbbvwgi6and2fokqess5tojy2u	573	5	P	P	NNP
work_dbbvwgi6and2fokqess5tojy2u	573	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	573	7	Nie	Nie	NNP
work_dbbvwgi6and2fokqess5tojy2u	573	8	E	E	NNP
work_dbbvwgi6and2fokqess5tojy2u	573	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	573	10	Kay	Kay	NNP
work_dbbvwgi6and2fokqess5tojy2u	573	11	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	573	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	573	13	Arrowsmith	Arrowsmith	NNP
work_dbbvwgi6and2fokqess5tojy2u	573	14	CH	CH	NNP
work_dbbvwgi6and2fokqess5tojy2u	573	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	574	1	Characterization	characterization	NN
work_dbbvwgi6and2fokqess5tojy2u	574	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	574	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	574	4	oligomerization	oligomerization	NN
work_dbbvwgi6and2fokqess5tojy2u	574	5	defects	defect	NNS
work_dbbvwgi6and2fokqess5tojy2u	574	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	574	7	two	two	CD
work_dbbvwgi6and2fokqess5tojy2u	574	8	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	574	9	mutants	mutant	NNS
work_dbbvwgi6and2fokqess5tojy2u	574	10	found	find	VBN
work_dbbvwgi6and2fokqess5tojy2u	574	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	574	12	families	family	NNS
work_dbbvwgi6and2fokqess5tojy2u	574	13	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	574	14	Li	Li	NNP
work_dbbvwgi6and2fokqess5tojy2u	574	15	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	574	16	Fraumeni	Fraumeni	NNP
work_dbbvwgi6and2fokqess5tojy2u	574	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	574	18	Li-	Li-	NNP
work_dbbvwgi6and2fokqess5tojy2u	574	19	Fraumeni	Fraumeni	NNP
work_dbbvwgi6and2fokqess5tojy2u	574	20	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	574	21	like	like	JJ
work_dbbvwgi6and2fokqess5tojy2u	574	22	syndrome	syndrome	NN
work_dbbvwgi6and2fokqess5tojy2u	574	23	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	575	1	Oncogene	oncogene	NN
work_dbbvwgi6and2fokqess5tojy2u	575	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	576	1	1998	1998	CD
work_dbbvwgi6and2fokqess5tojy2u	576	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	576	3	17	17	CD
work_dbbvwgi6and2fokqess5tojy2u	576	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	576	5	651	651	CD
work_dbbvwgi6and2fokqess5tojy2u	576	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	576	7	656	656	CD
work_dbbvwgi6and2fokqess5tojy2u	576	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	577	1	31	31	CD
work_dbbvwgi6and2fokqess5tojy2u	577	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	578	1	Lomax	Lomax	NNP
work_dbbvwgi6and2fokqess5tojy2u	578	2	ME	ME	NNP
work_dbbvwgi6and2fokqess5tojy2u	578	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	578	4	Barnes	Barnes	NNPS
work_dbbvwgi6and2fokqess5tojy2u	578	5	DM	DM	NNP
work_dbbvwgi6and2fokqess5tojy2u	578	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	578	7	Hupp	Hupp	NNP
work_dbbvwgi6and2fokqess5tojy2u	578	8	TR	TR	NNP
work_dbbvwgi6and2fokqess5tojy2u	578	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	578	10	Picksley	Picksley	NNP
work_dbbvwgi6and2fokqess5tojy2u	578	11	SM	SM	NNP
work_dbbvwgi6and2fokqess5tojy2u	578	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	578	13	Camplejohn	Camplejohn	NNP
work_dbbvwgi6and2fokqess5tojy2u	578	14	RS	RS	NNP
work_dbbvwgi6and2fokqess5tojy2u	578	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	579	1	Characterization	characterization	NN
work_dbbvwgi6and2fokqess5tojy2u	579	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	579	3	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	579	4	oligomerization	oligomerization	NN
work_dbbvwgi6and2fokqess5tojy2u	579	5	domain	domain	NN
work_dbbvwgi6and2fokqess5tojy2u	579	6	mutations	mutation	NNS
work_dbbvwgi6and2fokqess5tojy2u	579	7	isolated	isolate	VBN
work_dbbvwgi6and2fokqess5tojy2u	579	8	from	from	IN
work_dbbvwgi6and2fokqess5tojy2u	579	9	Li	Li	NNP
work_dbbvwgi6and2fokqess5tojy2u	579	10	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	579	11	Fraumeni	Fraumeni	NNP
work_dbbvwgi6and2fokqess5tojy2u	579	12	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	579	13	Li-	Li-	NNP
work_dbbvwgi6and2fokqess5tojy2u	579	14	Fraumeni	Fraumeni	NNP
work_dbbvwgi6and2fokqess5tojy2u	579	15	like	like	IN
work_dbbvwgi6and2fokqess5tojy2u	579	16	family	family	NN
work_dbbvwgi6and2fokqess5tojy2u	579	17	members	member	NNS
work_dbbvwgi6and2fokqess5tojy2u	579	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	580	1	Oncogene	oncogene	NN
work_dbbvwgi6and2fokqess5tojy2u	580	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	581	1	1998	1998	CD
work_dbbvwgi6and2fokqess5tojy2u	581	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	581	3	17	17	CD
work_dbbvwgi6and2fokqess5tojy2u	581	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	581	5	643-	643-	CD
work_dbbvwgi6and2fokqess5tojy2u	581	6	649	649	CD
work_dbbvwgi6and2fokqess5tojy2u	581	7	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	582	1	32	32	CD
work_dbbvwgi6and2fokqess5tojy2u	582	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	583	1	Cubillos	Cubillos	NNP
work_dbbvwgi6and2fokqess5tojy2u	583	2	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	583	3	Rojas	Rojas	NNP
work_dbbvwgi6and2fokqess5tojy2u	583	4	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	583	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	583	6	Amair	Amair	NNP
work_dbbvwgi6and2fokqess5tojy2u	583	7	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	583	8	Pinedo	Pinedo	NNP
work_dbbvwgi6and2fokqess5tojy2u	583	9	F	F	NNP
work_dbbvwgi6and2fokqess5tojy2u	583	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	583	11	Peiró	Peiró	NNP
work_dbbvwgi6and2fokqess5tojy2u	583	12	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	583	13	Jordán	Jordán	NNP
work_dbbvwgi6and2fokqess5tojy2u	583	14	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	583	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	583	16	Bartrons	Bartrons	NNPS
work_dbbvwgi6and2fokqess5tojy2u	583	17	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	583	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	583	19	Ventura	Ventura	NNP
work_dbbvwgi6and2fokqess5tojy2u	583	20	F	F	NNP
work_dbbvwgi6and2fokqess5tojy2u	583	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	583	22	Rosa	Rosa	NNP
work_dbbvwgi6and2fokqess5tojy2u	583	23	JL	JL	NNP
work_dbbvwgi6and2fokqess5tojy2u	583	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	584	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	584	2	E3	E3	NNP
work_dbbvwgi6and2fokqess5tojy2u	584	3	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	584	4	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	584	5	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	584	6	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	584	7	modulates	modulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	584	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	584	9	activity	activity	NN
work_dbbvwgi6and2fokqess5tojy2u	584	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	584	11	tumor	tumor	NN
work_dbbvwgi6and2fokqess5tojy2u	584	12	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	584	13	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	584	14	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	584	15	regulating	regulate	VBG
work_dbbvwgi6and2fokqess5tojy2u	584	16	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	584	17	oligomerization	oligomerization	NN
work_dbbvwgi6and2fokqess5tojy2u	584	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	585	1	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	585	2	Biol	Biol	NNP
work_dbbvwgi6and2fokqess5tojy2u	585	3	Chem	Chem	NNP
work_dbbvwgi6and2fokqess5tojy2u	585	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	586	1	2014	2014	CD
work_dbbvwgi6and2fokqess5tojy2u	586	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	586	3	289	289	CD
work_dbbvwgi6and2fokqess5tojy2u	586	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	586	5	14782	14782	CD
work_dbbvwgi6and2fokqess5tojy2u	586	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	586	7	14795	14795	CD
work_dbbvwgi6and2fokqess5tojy2u	586	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	587	1	33	33	CD
work_dbbvwgi6and2fokqess5tojy2u	587	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	588	1	Jones	Jones	NNP
work_dbbvwgi6and2fokqess5tojy2u	588	2	SN	SN	NNP
work_dbbvwgi6and2fokqess5tojy2u	588	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	588	4	Roe	Roe	NNP
work_dbbvwgi6and2fokqess5tojy2u	588	5	AE	AE	NNP
work_dbbvwgi6and2fokqess5tojy2u	588	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	588	7	Donehower	Donehower	NNP
work_dbbvwgi6and2fokqess5tojy2u	588	8	LA	LA	NNP
work_dbbvwgi6and2fokqess5tojy2u	588	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	588	10	Bradley	Bradley	NNP
work_dbbvwgi6and2fokqess5tojy2u	588	11	A.	a.	NN
work_dbbvwgi6and2fokqess5tojy2u	589	1	Rescue	rescue	NN
work_dbbvwgi6and2fokqess5tojy2u	589	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	589	3	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	589	4	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	589	5	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	589	6	Mdm2-deficient	mdm2-deficient	CD
work_dbbvwgi6and2fokqess5tojy2u	589	7	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	589	8	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	589	9	absence	absence	NN
work_dbbvwgi6and2fokqess5tojy2u	589	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	589	11	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	589	12	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	590	1	Nature	nature	NN
work_dbbvwgi6and2fokqess5tojy2u	590	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	591	1	1995	1995	CD
work_dbbvwgi6and2fokqess5tojy2u	591	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	591	3	378	378	CD
work_dbbvwgi6and2fokqess5tojy2u	591	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	591	5	206	206	CD
work_dbbvwgi6and2fokqess5tojy2u	591	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	591	7	208	208	CD
work_dbbvwgi6and2fokqess5tojy2u	591	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	592	1	34	34	CD
work_dbbvwgi6and2fokqess5tojy2u	592	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	593	1	Parant	Parant	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	2	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	593	4	Chavez	Chavez	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	593	6	Reyes	Reyes	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	7	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	593	9	Little	little	JJ
work_dbbvwgi6and2fokqess5tojy2u	593	10	NA	NA	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	593	12	Yan	Yan	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	13	W	W	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	593	15	Reinke	Reinke	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	16	V	V	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	593	18	Jochemsen	Jochemsen	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	19	AG	AG	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	593	21	Lozano	Lozano	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	22	G.	G.	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	23	Rescue	Rescue	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	24	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	593	25	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	593	26	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	593	27	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	593	28	Mdm4-null	Mdm4-null	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	29	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	593	30	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	593	31	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	593	32	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	593	33	Trp53	Trp53	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	34	suggests	suggest	VBZ
work_dbbvwgi6and2fokqess5tojy2u	593	35	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	593	36	nonoverlapping	nonoverlapping	JJ
work_dbbvwgi6and2fokqess5tojy2u	593	37	pathway	pathway	NN
work_dbbvwgi6and2fokqess5tojy2u	593	38	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	593	39	MDM2	MDM2	NNP
work_dbbvwgi6and2fokqess5tojy2u	593	40	to	to	TO
work_dbbvwgi6and2fokqess5tojy2u	593	41	regulate	regulate	VB
work_dbbvwgi6and2fokqess5tojy2u	593	42	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	593	43	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	594	1	Nat	Nat	NNP
work_dbbvwgi6and2fokqess5tojy2u	594	2	Genet	Genet	NNP
work_dbbvwgi6and2fokqess5tojy2u	594	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	595	1	2001	2001	CD
work_dbbvwgi6and2fokqess5tojy2u	595	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	595	3	29	29	CD
work_dbbvwgi6and2fokqess5tojy2u	595	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	595	5	92	92	CD
work_dbbvwgi6and2fokqess5tojy2u	595	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	595	7	95	95	CD
work_dbbvwgi6and2fokqess5tojy2u	595	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	596	1	Oncotarget56105www.impactjournals.com/oncotarget	oncotarget56105www.impactjournals.com/oncotarget	ADD
work_dbbvwgi6and2fokqess5tojy2u	596	2	35	35	CD
work_dbbvwgi6and2fokqess5tojy2u	596	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	597	1	Montes	Montes	NNP
work_dbbvwgi6and2fokqess5tojy2u	597	2	de	de	NNP
work_dbbvwgi6and2fokqess5tojy2u	597	3	Oca	Oca	NNP
work_dbbvwgi6and2fokqess5tojy2u	597	4	Luna	Luna	NNP
work_dbbvwgi6and2fokqess5tojy2u	597	5	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	597	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	597	7	Wagner	Wagner	NNP
work_dbbvwgi6and2fokqess5tojy2u	597	8	DS	DS	NNP
work_dbbvwgi6and2fokqess5tojy2u	597	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	597	10	Lozano	Lozano	NNP
work_dbbvwgi6and2fokqess5tojy2u	597	11	G.	G.	NNP
work_dbbvwgi6and2fokqess5tojy2u	597	12	Rescue	Rescue	NNP
work_dbbvwgi6and2fokqess5tojy2u	597	13	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	597	14	early	early	JJ
work_dbbvwgi6and2fokqess5tojy2u	597	15	embryonic	embryonic	JJ
work_dbbvwgi6and2fokqess5tojy2u	597	16	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	597	17	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	597	18	mdm2-deficient	mdm2-deficient	NNP
work_dbbvwgi6and2fokqess5tojy2u	597	19	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	597	20	by	by	IN
work_dbbvwgi6and2fokqess5tojy2u	597	21	deletion	deletion	NN
work_dbbvwgi6and2fokqess5tojy2u	597	22	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	597	23	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	597	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	598	1	Nature	nature	NN
work_dbbvwgi6and2fokqess5tojy2u	598	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	599	1	1995	1995	CD
work_dbbvwgi6and2fokqess5tojy2u	599	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	599	3	378	378	CD
work_dbbvwgi6and2fokqess5tojy2u	599	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	599	5	203	203	CD
work_dbbvwgi6and2fokqess5tojy2u	599	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	599	7	206	206	CD
work_dbbvwgi6and2fokqess5tojy2u	599	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	600	1	36	36	CD
work_dbbvwgi6and2fokqess5tojy2u	600	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	601	1	Donehower	Donehower	NNP
work_dbbvwgi6and2fokqess5tojy2u	601	2	LA	LA	NNP
work_dbbvwgi6and2fokqess5tojy2u	601	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	601	4	Harvey	Harvey	NNP
work_dbbvwgi6and2fokqess5tojy2u	601	5	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	601	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	601	7	Slagle	Slagle	NNP
work_dbbvwgi6and2fokqess5tojy2u	601	8	BL	BL	NNP
work_dbbvwgi6and2fokqess5tojy2u	601	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	601	10	McArthur	McArthur	NNP
work_dbbvwgi6and2fokqess5tojy2u	601	11	MJ	MJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	601	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	601	13	Montgomery	Montgomery	NNP
work_dbbvwgi6and2fokqess5tojy2u	601	14	CA	CA	NNP
work_dbbvwgi6and2fokqess5tojy2u	601	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	601	16	Butel	Butel	NNP
work_dbbvwgi6and2fokqess5tojy2u	601	17	JS	JS	NNP
work_dbbvwgi6and2fokqess5tojy2u	601	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	601	19	Bradley	Bradley	NNP
work_dbbvwgi6and2fokqess5tojy2u	601	20	A.	A.	NNP
work_dbbvwgi6and2fokqess5tojy2u	602	1	Mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	602	2	deficient	deficient	JJ
work_dbbvwgi6and2fokqess5tojy2u	602	3	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	602	4	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	602	5	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	602	6	developmentally	developmentally	RB
work_dbbvwgi6and2fokqess5tojy2u	602	7	normal	normal	JJ
work_dbbvwgi6and2fokqess5tojy2u	602	8	but	but	CC
work_dbbvwgi6and2fokqess5tojy2u	602	9	susceptible	susceptible	JJ
work_dbbvwgi6and2fokqess5tojy2u	602	10	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	602	11	spontaneous	spontaneous	JJ
work_dbbvwgi6and2fokqess5tojy2u	602	12	tumours	tumour	NNS
work_dbbvwgi6and2fokqess5tojy2u	602	13	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	603	1	Nature	nature	NN
work_dbbvwgi6and2fokqess5tojy2u	603	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	604	1	1992	1992	CD
work_dbbvwgi6and2fokqess5tojy2u	604	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	604	3	356	356	CD
work_dbbvwgi6and2fokqess5tojy2u	604	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	604	5	215	215	CD
work_dbbvwgi6and2fokqess5tojy2u	604	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	604	7	221	221	CD
work_dbbvwgi6and2fokqess5tojy2u	604	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	605	1	37	37	CD
work_dbbvwgi6and2fokqess5tojy2u	605	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	606	1	Jacks	Jacks	NNP
work_dbbvwgi6and2fokqess5tojy2u	606	2	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	606	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	606	4	Remington	Remington	NNP
work_dbbvwgi6and2fokqess5tojy2u	606	5	L	L	NNP
work_dbbvwgi6and2fokqess5tojy2u	606	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	606	7	Williams	Williams	NNP
work_dbbvwgi6and2fokqess5tojy2u	606	8	BO	BO	NNP
work_dbbvwgi6and2fokqess5tojy2u	606	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	606	10	Schmitt	Schmitt	NNP
work_dbbvwgi6and2fokqess5tojy2u	606	11	EM	EM	NNP
work_dbbvwgi6and2fokqess5tojy2u	606	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	606	13	Halachmi	Halachmi	NNP
work_dbbvwgi6and2fokqess5tojy2u	606	14	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	606	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	606	16	Bronson	Bronson	NNP
work_dbbvwgi6and2fokqess5tojy2u	606	17	RT	RT	NNP
work_dbbvwgi6and2fokqess5tojy2u	606	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	606	19	Weinberg	Weinberg	NNP
work_dbbvwgi6and2fokqess5tojy2u	606	20	RA	RA	NNP
work_dbbvwgi6and2fokqess5tojy2u	606	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	607	1	Tumor	tumor	NN
work_dbbvwgi6and2fokqess5tojy2u	607	2	spectrum	spectrum	NN
work_dbbvwgi6and2fokqess5tojy2u	607	3	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	607	4	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	607	5	p53-mutant	p53-mutant	CD
work_dbbvwgi6and2fokqess5tojy2u	607	6	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	607	7	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	608	1	Curr	Curr	NNP
work_dbbvwgi6and2fokqess5tojy2u	608	2	Biol	Biol	NNP
work_dbbvwgi6and2fokqess5tojy2u	608	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	609	1	1994	1994	CD
work_dbbvwgi6and2fokqess5tojy2u	609	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	609	3	4	4	CD
work_dbbvwgi6and2fokqess5tojy2u	609	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	609	5	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	609	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	609	7	7	7	CD
work_dbbvwgi6and2fokqess5tojy2u	609	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	610	1	38	38	CD
work_dbbvwgi6and2fokqess5tojy2u	610	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	611	1	Donehower	Donehower	NNP
work_dbbvwgi6and2fokqess5tojy2u	611	2	L	L	NNP
work_dbbvwgi6and2fokqess5tojy2u	611	3	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	611	4	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	611	5	Lozano	Lozano	NNP
work_dbbvwgi6and2fokqess5tojy2u	611	6	G.	G.	NNP
work_dbbvwgi6and2fokqess5tojy2u	611	7	20	20	CD
work_dbbvwgi6and2fokqess5tojy2u	611	8	Years	year	NNS
work_dbbvwgi6and2fokqess5tojy2u	611	9	Studying	Studying	NNP
work_dbbvwgi6and2fokqess5tojy2u	611	10	P53	P53	NNP
work_dbbvwgi6and2fokqess5tojy2u	611	11	Functions	function	NNS
work_dbbvwgi6and2fokqess5tojy2u	611	12	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	611	13	Genetically	Genetically	NNP
work_dbbvwgi6and2fokqess5tojy2u	611	14	Engineered	engineer	VBN
work_dbbvwgi6and2fokqess5tojy2u	611	15	Mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	611	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	612	1	Nat	Nat	NNP
work_dbbvwgi6and2fokqess5tojy2u	612	2	Rev	Rev	NNP
work_dbbvwgi6and2fokqess5tojy2u	612	3	Cancer	Cancer	NNP
work_dbbvwgi6and2fokqess5tojy2u	612	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	613	1	2009	2009	CD
work_dbbvwgi6and2fokqess5tojy2u	613	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	613	3	9	9	CD
work_dbbvwgi6and2fokqess5tojy2u	613	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	613	5	831	831	CD
work_dbbvwgi6and2fokqess5tojy2u	613	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	613	7	41	41	CD
work_dbbvwgi6and2fokqess5tojy2u	613	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	614	1	39	39	CD
work_dbbvwgi6and2fokqess5tojy2u	614	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	615	1	Li	Li	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	2	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	615	4	Kon	Kon	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	5	N	N	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	615	7	Jiang	Jiang	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	8	L	L	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	615	10	Tan	Tan	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	11	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	615	13	Ludwig	Ludwig	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	14	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	615	16	Zhao	Zhao	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	17	Y	Y	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	615	19	Baer	Baer	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	20	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	615	22	Gu	Gu	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	23	W.	W.	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	24	Tumor	Tumor	NNP
work_dbbvwgi6and2fokqess5tojy2u	615	25	suppression	suppression	NN
work_dbbvwgi6and2fokqess5tojy2u	615	26	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	615	27	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	615	28	absence	absence	NN
work_dbbvwgi6and2fokqess5tojy2u	615	29	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	615	30	p53-mediated	p53-mediated	JJ
work_dbbvwgi6and2fokqess5tojy2u	615	31	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	615	32	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	615	33	cycle	cycle	NN
work_dbbvwgi6and2fokqess5tojy2u	615	34	arrest	arrest	NN
work_dbbvwgi6and2fokqess5tojy2u	615	35	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	615	36	apoptosis	apoptosis	NN
work_dbbvwgi6and2fokqess5tojy2u	615	37	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	615	38	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	615	39	senescence	senescence	NN
work_dbbvwgi6and2fokqess5tojy2u	615	40	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	616	1	Cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	616	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	617	1	2012	2012	CD
work_dbbvwgi6and2fokqess5tojy2u	617	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	617	3	149	149	CD
work_dbbvwgi6and2fokqess5tojy2u	617	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	617	5	1269	1269	CD
work_dbbvwgi6and2fokqess5tojy2u	617	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	617	7	1283	1283	CD
work_dbbvwgi6and2fokqess5tojy2u	617	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	618	1	40	40	CD
work_dbbvwgi6and2fokqess5tojy2u	618	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	619	1	Brady	Brady	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	2	CA	CA	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	619	4	Jiang	Jiang	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	5	D	D	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	619	7	Mello	Mello	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	8	SS	SS	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	619	10	Johnson	Johnson	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	11	TM	TM	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	619	13	Jarvis	Jarvis	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	14	LA	LA	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	619	16	Kozak	Kozak	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	17	MM	MM	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	619	19	Broz	Broz	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	20	DK	DK	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	619	22	Basak	Basak	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	23	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	619	25	Park	Park	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	26	EJ	EJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	27	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	619	28	McLaughlin	McLaughlin	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	29	ME	ME	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	30	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	619	31	Karnezis	Karnezis	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	32	AN	AN	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	33	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	619	34	Attardi	Attardi	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	35	LD	LD	NNP
work_dbbvwgi6and2fokqess5tojy2u	619	36	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	620	1	Distinct	distinct	JJ
work_dbbvwgi6and2fokqess5tojy2u	620	2	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	620	3	transcriptional	transcriptional	JJ
work_dbbvwgi6and2fokqess5tojy2u	620	4	programs	program	NNS
work_dbbvwgi6and2fokqess5tojy2u	620	5	dictate	dictate	VBP
work_dbbvwgi6and2fokqess5tojy2u	620	6	acute	acute	JJ
work_dbbvwgi6and2fokqess5tojy2u	620	7	DNA	dna	NN
work_dbbvwgi6and2fokqess5tojy2u	620	8	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	620	9	damage	damage	NN
work_dbbvwgi6and2fokqess5tojy2u	620	10	responses	response	NNS
work_dbbvwgi6and2fokqess5tojy2u	620	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	620	12	tumor	tumor	NN
work_dbbvwgi6and2fokqess5tojy2u	620	13	suppression	suppression	NN
work_dbbvwgi6and2fokqess5tojy2u	620	14	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	621	1	Cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	621	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	622	1	2011	2011	CD
work_dbbvwgi6and2fokqess5tojy2u	622	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	622	3	145	145	CD
work_dbbvwgi6and2fokqess5tojy2u	622	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	622	5	571	571	CD
work_dbbvwgi6and2fokqess5tojy2u	622	6	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	622	7	583	583	CD
work_dbbvwgi6and2fokqess5tojy2u	622	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	623	1	41	41	CD
work_dbbvwgi6and2fokqess5tojy2u	623	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	624	1	Valente	Valente	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	2	LJ	LJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	624	4	Gray	Gray	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	5	DHD	DHD	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	624	7	Michalak	Michalak	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	8	EM	EM	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	624	10	Pinon	Pinon	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	11	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	624	12	Hofbauer	Hofbauer	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	13	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	624	15	Egle	Egle	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	16	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	624	18	Scott	Scott	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	19	CL	CL	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	624	21	Janic	Janic	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	22	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	624	24	Strasser	Strasser	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	25	A.	a.	NN
work_dbbvwgi6and2fokqess5tojy2u	624	26	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	624	27	efficiently	efficiently	RB
work_dbbvwgi6and2fokqess5tojy2u	624	28	suppresses	suppress	VBZ
work_dbbvwgi6and2fokqess5tojy2u	624	29	tumor	tumor	NN
work_dbbvwgi6and2fokqess5tojy2u	624	30	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	624	31	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	624	32	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	624	33	complete	complete	JJ
work_dbbvwgi6and2fokqess5tojy2u	624	34	absence	absence	NN
work_dbbvwgi6and2fokqess5tojy2u	624	35	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	624	36	its	-PRON-	PRP$
work_dbbvwgi6and2fokqess5tojy2u	624	37	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	624	38	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	624	39	cycle	cycle	NN
work_dbbvwgi6and2fokqess5tojy2u	624	40	inhibitory	inhibitory	NN
work_dbbvwgi6and2fokqess5tojy2u	624	41	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	624	42	proapoptotic	proapoptotic	JJ
work_dbbvwgi6and2fokqess5tojy2u	624	43	effectors	effector	NNS
work_dbbvwgi6and2fokqess5tojy2u	624	44	p21	p21	NN
work_dbbvwgi6and2fokqess5tojy2u	624	45	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	624	46	Puma	Puma	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	47	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	624	48	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	624	49	Noxa	Noxa	NNP
work_dbbvwgi6and2fokqess5tojy2u	624	50	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	625	1	Cell	Cell	NNP
work_dbbvwgi6and2fokqess5tojy2u	625	2	Rep.	Rep.	NNP
work_dbbvwgi6and2fokqess5tojy2u	625	3	2013	2013	CD
work_dbbvwgi6and2fokqess5tojy2u	625	4	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	625	5	3	3	CD
work_dbbvwgi6and2fokqess5tojy2u	625	6	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	625	7	1339	1339	CD
work_dbbvwgi6and2fokqess5tojy2u	625	8	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	625	9	1345	1345	CD
work_dbbvwgi6and2fokqess5tojy2u	625	10	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	626	1	42	42	CD
work_dbbvwgi6and2fokqess5tojy2u	626	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	627	1	Dusart	Dusart	NNP
work_dbbvwgi6and2fokqess5tojy2u	627	2	I	I	NNP
work_dbbvwgi6and2fokqess5tojy2u	627	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	627	4	Guenet	Guenet	NNP
work_dbbvwgi6and2fokqess5tojy2u	627	5	JL	JL	NNP
work_dbbvwgi6and2fokqess5tojy2u	627	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	627	7	Sotelo	Sotelo	NNP
work_dbbvwgi6and2fokqess5tojy2u	627	8	C.	C.	NNP
work_dbbvwgi6and2fokqess5tojy2u	627	9	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	627	10	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	627	11	death	death	NN
work_dbbvwgi6and2fokqess5tojy2u	627	12	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	627	13	differences	difference	NNS
work_dbbvwgi6and2fokqess5tojy2u	627	14	between	between	IN
work_dbbvwgi6and2fokqess5tojy2u	627	15	developmental	developmental	JJ
work_dbbvwgi6and2fokqess5tojy2u	627	16	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	627	17	death	death	NN
work_dbbvwgi6and2fokqess5tojy2u	627	18	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	627	19	neurodegenerative	neurodegenerative	JJ
work_dbbvwgi6and2fokqess5tojy2u	627	20	death	death	NN
work_dbbvwgi6and2fokqess5tojy2u	627	21	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	627	22	mutant	mutant	JJ
work_dbbvwgi6and2fokqess5tojy2u	627	23	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	627	24	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	628	1	Cerebellum	cerebellum	NN
work_dbbvwgi6and2fokqess5tojy2u	628	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	629	1	2006	2006	CD
work_dbbvwgi6and2fokqess5tojy2u	629	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	629	3	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	629	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	629	5	163	163	CD
work_dbbvwgi6and2fokqess5tojy2u	629	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	629	7	173	173	CD
work_dbbvwgi6and2fokqess5tojy2u	629	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	630	1	43	43	CD
work_dbbvwgi6and2fokqess5tojy2u	630	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	631	1	Hawkes	Hawkes	NNP
work_dbbvwgi6and2fokqess5tojy2u	631	2	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	631	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	631	4	colonnier	colonni	JJR
work_dbbvwgi6and2fokqess5tojy2u	631	5	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	631	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	631	7	Leclerc	Leclerc	NNP
work_dbbvwgi6and2fokqess5tojy2u	631	8	N.	N.	NNP
work_dbbvwgi6and2fokqess5tojy2u	631	9	Monoclonal	Monoclonal	NNP
work_dbbvwgi6and2fokqess5tojy2u	631	10	antibodies	antibody	NNS
work_dbbvwgi6and2fokqess5tojy2u	631	11	reveal	reveal	VBP
work_dbbvwgi6and2fokqess5tojy2u	631	12	sagittal	sagittal	JJ
work_dbbvwgi6and2fokqess5tojy2u	631	13	banding	banding	NN
work_dbbvwgi6and2fokqess5tojy2u	631	14	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	631	15	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	631	16	rodent	rodent	NN
work_dbbvwgi6and2fokqess5tojy2u	631	17	cerebellar	cerebellar	NNP
work_dbbvwgi6and2fokqess5tojy2u	631	18	cortex	cortex	NNP
work_dbbvwgi6and2fokqess5tojy2u	631	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	632	1	Brain	Brain	NNP
work_dbbvwgi6and2fokqess5tojy2u	632	2	Res	Res	NNP
work_dbbvwgi6and2fokqess5tojy2u	632	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	633	1	1985	1985	CD
work_dbbvwgi6and2fokqess5tojy2u	633	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	633	3	333	333	CD
work_dbbvwgi6and2fokqess5tojy2u	633	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	633	5	359	359	CD
work_dbbvwgi6and2fokqess5tojy2u	633	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	633	7	365	365	CD
work_dbbvwgi6and2fokqess5tojy2u	633	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	634	1	44	44	CD
work_dbbvwgi6and2fokqess5tojy2u	634	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	635	1	Mashimo	Mashimo	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	2	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	635	4	Hadjebi	Hadjebi	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	5	O	O	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	635	7	Amair	Amair	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	8	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	635	9	Pinedo	Pinedo	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	10	F	F	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	635	12	Tsurumi	Tsurumi	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	13	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	635	15	Langa	Langa	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	16	F	F	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	635	18	Serikawa	Serikawa	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	19	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	635	21	Sotelo	Sotelo	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	22	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	635	24	Guenet	Guenet	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	25	JL	JL	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	26	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	635	27	Rosa	Rosa	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	28	JL	JL	NNP
work_dbbvwgi6and2fokqess5tojy2u	635	29	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	636	1	Progressive	Progressive	NNP
work_dbbvwgi6and2fokqess5tojy2u	636	2	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	636	3	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	636	4	degeneration	degeneration	NN
work_dbbvwgi6and2fokqess5tojy2u	636	5	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	636	6	tambaleante	tambaleante	JJ
work_dbbvwgi6and2fokqess5tojy2u	636	7	mutant	mutant	JJ
work_dbbvwgi6and2fokqess5tojy2u	636	8	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	636	9	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	636	10	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	636	11	consequence	consequence	NN
work_dbbvwgi6and2fokqess5tojy2u	636	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	636	13	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	636	14	missense	missense	NN
work_dbbvwgi6and2fokqess5tojy2u	636	15	mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	636	16	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	636	17	HERC1	herc1	NN
work_dbbvwgi6and2fokqess5tojy2u	636	18	E3	E3	NNP
work_dbbvwgi6and2fokqess5tojy2u	636	19	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	636	20	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	636	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	637	1	PLoS	PLoS	NNP
work_dbbvwgi6and2fokqess5tojy2u	637	2	Genet	Genet	NNP
work_dbbvwgi6and2fokqess5tojy2u	637	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	638	1	2009	2009	CD
work_dbbvwgi6and2fokqess5tojy2u	638	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	638	3	5	5	CD
work_dbbvwgi6and2fokqess5tojy2u	638	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	638	5	e1000784	e1000784	NNP
work_dbbvwgi6and2fokqess5tojy2u	638	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	639	1	45	45	CD
work_dbbvwgi6and2fokqess5tojy2u	639	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	640	1	Ruiz	Ruiz	NNP
work_dbbvwgi6and2fokqess5tojy2u	640	2	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	640	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	640	4	Pérez	Pérez	NNP
work_dbbvwgi6and2fokqess5tojy2u	640	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	640	6	Villegas	Villegas	NNP
work_dbbvwgi6and2fokqess5tojy2u	640	7	EM	EM	NNP
work_dbbvwgi6and2fokqess5tojy2u	640	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	640	9	Bachiller	Bachiller	NNP
work_dbbvwgi6and2fokqess5tojy2u	640	10	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	640	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	640	12	Rosa	Rosa	NNP
work_dbbvwgi6and2fokqess5tojy2u	640	13	JL	JL	NNP
work_dbbvwgi6and2fokqess5tojy2u	640	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	640	15	Armengol	Armengol	NNP
work_dbbvwgi6and2fokqess5tojy2u	640	16	JA	JA	NNP
work_dbbvwgi6and2fokqess5tojy2u	640	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	641	1	HERC	HERC	NNP
work_dbbvwgi6and2fokqess5tojy2u	641	2	1	1	CD
work_dbbvwgi6and2fokqess5tojy2u	641	3	Ubiquitin	Ubiquitin	NNP
work_dbbvwgi6and2fokqess5tojy2u	641	4	Ligase	Ligase	NNP
work_dbbvwgi6and2fokqess5tojy2u	641	5	Mutation	mutation	NN
work_dbbvwgi6and2fokqess5tojy2u	641	6	Affects	affect	VBZ
work_dbbvwgi6and2fokqess5tojy2u	641	7	Neocortical	Neocortical	NNP
work_dbbvwgi6and2fokqess5tojy2u	641	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	641	9	CA3	CA3	NNP
work_dbbvwgi6and2fokqess5tojy2u	641	10	Hippocampal	Hippocampal	NNP
work_dbbvwgi6and2fokqess5tojy2u	641	11	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	641	12	Spinal	Spinal	NNP
work_dbbvwgi6and2fokqess5tojy2u	641	13	Cord	Cord	NNP
work_dbbvwgi6and2fokqess5tojy2u	641	14	Projection	Projection	NNP
work_dbbvwgi6and2fokqess5tojy2u	641	15	Neurons	Neurons	NNPS
work_dbbvwgi6and2fokqess5tojy2u	641	16	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	641	17	An	an	DT
work_dbbvwgi6and2fokqess5tojy2u	641	18	Ultrastructural	Ultrastructural	NNP
work_dbbvwgi6and2fokqess5tojy2u	641	19	Study	Study	NNP
work_dbbvwgi6and2fokqess5tojy2u	641	20	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	642	1	Front	front	JJ
work_dbbvwgi6and2fokqess5tojy2u	642	2	Neuroanat	Neuroanat	NNP
work_dbbvwgi6and2fokqess5tojy2u	642	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	643	1	2016	2016	CD
work_dbbvwgi6and2fokqess5tojy2u	643	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	643	3	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	643	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	643	5	42	42	CD
work_dbbvwgi6and2fokqess5tojy2u	643	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	644	1	46	46	CD
work_dbbvwgi6and2fokqess5tojy2u	644	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	645	1	Bachiller	Bachiller	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	2	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	645	4	Rybkina	Rybkina	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	5	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	645	7	Porras	Porras	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	8	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	645	9	García	García	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	10	E	E	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	645	12	Pérez	Pérez	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	13	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	645	14	Villegas	Villegas	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	15	E	E	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	645	17	Tabares	Tabares	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	18	L	L	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	645	20	Armengol	Armengol	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	21	JA	JA	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	22	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	645	23	Carrión	Carrión	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	24	AM	AM	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	25	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	645	26	Ruiz	Ruiz	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	27	R.	R.	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	28	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	645	29	HERC1	HERC1	NNS
work_dbbvwgi6and2fokqess5tojy2u	645	30	E3	E3	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	31	Ubiquitin	Ubiquitin	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	32	Ligase	Ligase	NNP
work_dbbvwgi6and2fokqess5tojy2u	645	33	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	645	34	essential	essential	JJ
work_dbbvwgi6and2fokqess5tojy2u	645	35	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	645	36	normal	normal	JJ
work_dbbvwgi6and2fokqess5tojy2u	645	37	development	development	NN
work_dbbvwgi6and2fokqess5tojy2u	645	38	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	645	39	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	645	40	neurotransmission	neurotransmission	NN
work_dbbvwgi6and2fokqess5tojy2u	645	41	at	at	IN
work_dbbvwgi6and2fokqess5tojy2u	645	42	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	645	43	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	645	44	neuromuscular	neuromuscular	JJ
work_dbbvwgi6and2fokqess5tojy2u	645	45	junction	junction	NN
work_dbbvwgi6and2fokqess5tojy2u	645	46	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	646	1	Cell	Cell	NNP
work_dbbvwgi6and2fokqess5tojy2u	646	2	Mol	Mol	NNP
work_dbbvwgi6and2fokqess5tojy2u	646	3	Life	Life	NNP
work_dbbvwgi6and2fokqess5tojy2u	646	4	Sci	Sci	NNP
work_dbbvwgi6and2fokqess5tojy2u	646	5	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	647	1	2015	2015	CD
work_dbbvwgi6and2fokqess5tojy2u	647	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	647	3	72	72	CD
work_dbbvwgi6and2fokqess5tojy2u	647	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	647	5	2961	2961	CD
work_dbbvwgi6and2fokqess5tojy2u	647	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	647	7	2971	2971	CD
work_dbbvwgi6and2fokqess5tojy2u	647	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	648	1	47	47	CD
work_dbbvwgi6and2fokqess5tojy2u	648	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	649	1	Galligan	Galligan	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	2	JT	JT	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	649	4	Martinez	Martinez	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	649	6	Noël	Noël	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	7	G	G	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	649	9	Arndt	Arndt	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	10	V	V	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	649	12	Hayes	Hayes	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	13	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	649	15	Chittenden	Chittenden	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	16	TW	TW	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	649	18	Harper	Harper	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	19	JW	JW	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	649	21	Howley	Howley	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	22	PM	PM	NNP
work_dbbvwgi6and2fokqess5tojy2u	649	23	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	650	1	Proteomic	proteomic	JJ
work_dbbvwgi6and2fokqess5tojy2u	650	2	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	650	3	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	650	4	identification	identification	NN
work_dbbvwgi6and2fokqess5tojy2u	650	5	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	650	6	cellular	cellular	JJ
work_dbbvwgi6and2fokqess5tojy2u	650	7	interactors	interactor	NNS
work_dbbvwgi6and2fokqess5tojy2u	650	8	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	650	9	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	650	10	giant	giant	JJ
work_dbbvwgi6and2fokqess5tojy2u	650	11	ubiquitin	ubiquitin	JJ
work_dbbvwgi6and2fokqess5tojy2u	650	12	ligase	ligase	NN
work_dbbvwgi6and2fokqess5tojy2u	650	13	HERC2	HERC2	NNP
work_dbbvwgi6and2fokqess5tojy2u	650	14	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	651	1	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	651	2	Proteome	Proteome	NNP
work_dbbvwgi6and2fokqess5tojy2u	651	3	Res	Res	NNP
work_dbbvwgi6and2fokqess5tojy2u	651	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	652	1	2015	2015	CD
work_dbbvwgi6and2fokqess5tojy2u	652	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	652	3	14	14	CD
work_dbbvwgi6and2fokqess5tojy2u	652	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	652	5	953-	953-	CD
work_dbbvwgi6and2fokqess5tojy2u	652	6	966	966	CD
work_dbbvwgi6and2fokqess5tojy2u	652	7	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	653	1	48	48	CD
work_dbbvwgi6and2fokqess5tojy2u	653	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	654	1	Campana	Campana	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	2	ALM	ALM	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	654	4	Rondi	Rondi	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	654	6	Reig	Reig	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	7	L	L	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	654	9	Tobin	Tobin	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	10	C	C	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	654	12	Lohof	Lohof	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	13	AM	am	NN
work_dbbvwgi6and2fokqess5tojy2u	654	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	654	15	Picquet	Picquet	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	16	F	F	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	654	18	Falempin	Falempin	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	19	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	654	21	Weitzman	Weitzman	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	22	JB	JB	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	654	24	Mariani	Mariani	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	25	J.	J.	NNP
work_dbbvwgi6and2fokqess5tojy2u	654	26	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	654	27	inactivation	inactivation	NN
work_dbbvwgi6and2fokqess5tojy2u	654	28	leads	lead	VBZ
work_dbbvwgi6and2fokqess5tojy2u	654	29	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	654	30	impaired	impaired	JJ
work_dbbvwgi6and2fokqess5tojy2u	654	31	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	654	32	synchronization	synchronization	NN
work_dbbvwgi6and2fokqess5tojy2u	654	33	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	654	34	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	654	35	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	655	1	Eur	Eur	NNP
work_dbbvwgi6and2fokqess5tojy2u	655	2	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	655	3	Neurosci	Neurosci	NNP
work_dbbvwgi6and2fokqess5tojy2u	655	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	656	1	2003	2003	CD
work_dbbvwgi6and2fokqess5tojy2u	656	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	656	3	17	17	CD
work_dbbvwgi6and2fokqess5tojy2u	656	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	656	5	2135	2135	CD
work_dbbvwgi6and2fokqess5tojy2u	656	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	656	7	2146	2146	CD
work_dbbvwgi6and2fokqess5tojy2u	656	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	657	1	49	49	CD
work_dbbvwgi6and2fokqess5tojy2u	657	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	658	1	Tomasevic	Tomasevic	NNP
work_dbbvwgi6and2fokqess5tojy2u	658	2	G	G	NNP
work_dbbvwgi6and2fokqess5tojy2u	658	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	658	4	Raghupathi	Raghupathi	NNP
work_dbbvwgi6and2fokqess5tojy2u	658	5	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	658	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	658	7	Scherbel	Scherbel	NNP
work_dbbvwgi6and2fokqess5tojy2u	658	8	U	U	NNP
work_dbbvwgi6and2fokqess5tojy2u	658	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	658	10	Wieloch	Wieloch	NNP
work_dbbvwgi6and2fokqess5tojy2u	658	11	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	658	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	658	13	McIntosh	McIntosh	NNP
work_dbbvwgi6and2fokqess5tojy2u	658	14	TK	TK	NNP
work_dbbvwgi6and2fokqess5tojy2u	658	15	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	659	1	Deletion	deletion	NN
work_dbbvwgi6and2fokqess5tojy2u	659	2	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	659	3	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	659	4	p53	p53	NN
work_dbbvwgi6and2fokqess5tojy2u	659	5	tumor	tumor	NN
work_dbbvwgi6and2fokqess5tojy2u	659	6	suppressor	suppressor	NN
work_dbbvwgi6and2fokqess5tojy2u	659	7	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	659	8	improves	improve	VBZ
work_dbbvwgi6and2fokqess5tojy2u	659	9	neuromotor	neuromotor	NN
work_dbbvwgi6and2fokqess5tojy2u	659	10	function	function	NN
work_dbbvwgi6and2fokqess5tojy2u	659	11	but	but	CC
work_dbbvwgi6and2fokqess5tojy2u	659	12	does	do	VBZ
work_dbbvwgi6and2fokqess5tojy2u	659	13	not	not	RB
work_dbbvwgi6and2fokqess5tojy2u	659	14	attenuate	attenuate	VB
work_dbbvwgi6and2fokqess5tojy2u	659	15	regional	regional	JJ
work_dbbvwgi6and2fokqess5tojy2u	659	16	neuronal	neuronal	JJ
work_dbbvwgi6and2fokqess5tojy2u	659	17	cell	cell	NN
work_dbbvwgi6and2fokqess5tojy2u	659	18	loss	loss	NN
work_dbbvwgi6and2fokqess5tojy2u	659	19	following	follow	VBG
work_dbbvwgi6and2fokqess5tojy2u	659	20	experimental	experimental	JJ
work_dbbvwgi6and2fokqess5tojy2u	659	21	brain	brain	NN
work_dbbvwgi6and2fokqess5tojy2u	659	22	trauma	trauma	NN
work_dbbvwgi6and2fokqess5tojy2u	659	23	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	659	24	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	659	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	660	1	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	660	2	Neurosci	Neurosci	NNP
work_dbbvwgi6and2fokqess5tojy2u	660	3	Res	Res	NNP
work_dbbvwgi6and2fokqess5tojy2u	660	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	661	1	2010	2010	CD
work_dbbvwgi6and2fokqess5tojy2u	661	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	661	3	88	88	CD
work_dbbvwgi6and2fokqess5tojy2u	661	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	661	5	3414	3414	CD
work_dbbvwgi6and2fokqess5tojy2u	661	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	661	7	3423	3423	CD
work_dbbvwgi6and2fokqess5tojy2u	661	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	662	1	50	50	CD
work_dbbvwgi6and2fokqess5tojy2u	662	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	663	1	Walkowicz	Walkowicz	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	2	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	663	4	Ji	Ji	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	5	Y	Y	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	663	7	Ren	Ren	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	8	X	X	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	663	10	Horsthemke	Horsthemke	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	11	B	B	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	663	13	Russell	Russell	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	14	LB	LB	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	663	16	Johnson	Johnson	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	17	D	D	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	663	19	Rinchik	Rinchik	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	20	EM	EM	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	663	22	Nicholls	Nicholls	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	23	RD	RD	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	663	25	Stubbs	Stubbs	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	26	L.	L.	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	27	Molecular	Molecular	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	28	characterization	characterization	NN
work_dbbvwgi6and2fokqess5tojy2u	663	29	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	663	30	radiation-	radiation-	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	31	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	663	32	chemically	chemically	RB
work_dbbvwgi6and2fokqess5tojy2u	663	33	induced	induce	VBN
work_dbbvwgi6and2fokqess5tojy2u	663	34	mutations	mutation	NNS
work_dbbvwgi6and2fokqess5tojy2u	663	35	associated	associate	VBN
work_dbbvwgi6and2fokqess5tojy2u	663	36	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	663	37	neuromuscular	neuromuscular	JJ
work_dbbvwgi6and2fokqess5tojy2u	663	38	tremors	tremor	NNS
work_dbbvwgi6and2fokqess5tojy2u	663	39	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	663	40	runting	runting	NN
work_dbbvwgi6and2fokqess5tojy2u	663	41	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	663	42	juvenile	juvenile	JJ
work_dbbvwgi6and2fokqess5tojy2u	663	43	lethality	lethality	NN
work_dbbvwgi6and2fokqess5tojy2u	663	44	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	663	45	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	663	46	sperm	sperm	JJ
work_dbbvwgi6and2fokqess5tojy2u	663	47	defects	defect	NNS
work_dbbvwgi6and2fokqess5tojy2u	663	48	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	663	49	jdf2	jdf2	NNP
work_dbbvwgi6and2fokqess5tojy2u	663	50	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	663	51	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	664	1	Mamm	mamm	RB
work_dbbvwgi6and2fokqess5tojy2u	664	2	Genome	genome	JJ
work_dbbvwgi6and2fokqess5tojy2u	664	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	665	1	1999	1999	CD
work_dbbvwgi6and2fokqess5tojy2u	665	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	665	3	10	10	CD
work_dbbvwgi6and2fokqess5tojy2u	665	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	665	5	870	870	CD
work_dbbvwgi6and2fokqess5tojy2u	665	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	665	7	878	878	CD
work_dbbvwgi6and2fokqess5tojy2u	665	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	666	1	51	51	CD
work_dbbvwgi6and2fokqess5tojy2u	666	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	667	1	Ji	Ji	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	2	Y	Y	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	667	4	Walkowicz	Walkowicz	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	5	MJ	MJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	667	7	Buiting	Buiting	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	8	K	K	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	667	10	Johnson	Johnson	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	11	DK	DK	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	667	13	Tarvin	Tarvin	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	14	RE	RE	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	667	16	Rinchik	Rinchik	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	17	EM	em	NN
work_dbbvwgi6and2fokqess5tojy2u	667	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	667	19	Horsthemke	Horsthemke	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	20	B	B	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	667	22	Stubbs	Stubbs	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	23	L	L	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	667	25	Nicholls	Nicholls	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	26	RD	RD	NNP
work_dbbvwgi6and2fokqess5tojy2u	667	27	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	668	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	668	2	ancestral	ancestral	JJ
work_dbbvwgi6and2fokqess5tojy2u	668	3	gene	gene	NN
work_dbbvwgi6and2fokqess5tojy2u	668	4	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	668	5	transcribed	transcribed	NNP
work_dbbvwgi6and2fokqess5tojy2u	668	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	668	7	low	low	JJ
work_dbbvwgi6and2fokqess5tojy2u	668	8	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	668	9	copy	copy	NN
work_dbbvwgi6and2fokqess5tojy2u	668	10	repeats	repeat	NNS
work_dbbvwgi6and2fokqess5tojy2u	668	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	668	12	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	668	13	Prader	Prader	NNP
work_dbbvwgi6and2fokqess5tojy2u	668	14	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	668	15	Willi	Willi	NNP
work_dbbvwgi6and2fokqess5tojy2u	668	16	/	/	SYM
work_dbbvwgi6and2fokqess5tojy2u	668	17	Angelman	Angelman	NNP
work_dbbvwgi6and2fokqess5tojy2u	668	18	region	region	NN
work_dbbvwgi6and2fokqess5tojy2u	668	19	encodes	encode	VBZ
work_dbbvwgi6and2fokqess5tojy2u	668	20	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	668	21	large	large	JJ
work_dbbvwgi6and2fokqess5tojy2u	668	22	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	668	23	implicated	implicate	VBN
work_dbbvwgi6and2fokqess5tojy2u	668	24	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	668	25	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	668	26	trafficking	trafficking	NN
work_dbbvwgi6and2fokqess5tojy2u	668	27	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	668	28	which	which	WDT
work_dbbvwgi6and2fokqess5tojy2u	668	29	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	668	30	deficient	deficient	JJ
work_dbbvwgi6and2fokqess5tojy2u	668	31	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	668	32	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	668	33	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	668	34	neuromuscular	neuromuscular	JJ
work_dbbvwgi6and2fokqess5tojy2u	668	35	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	668	36	spermiogenic	spermiogenic	JJ
work_dbbvwgi6and2fokqess5tojy2u	668	37	abnormalities	abnormality	NNS
work_dbbvwgi6and2fokqess5tojy2u	668	38	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	669	1	Hum	Hum	NNP
work_dbbvwgi6and2fokqess5tojy2u	669	2	Mol	Mol	NNP
work_dbbvwgi6and2fokqess5tojy2u	669	3	Genet	Genet	NNP
work_dbbvwgi6and2fokqess5tojy2u	669	4	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	670	1	1999	1999	CD
work_dbbvwgi6and2fokqess5tojy2u	670	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	670	3	8	8	CD
work_dbbvwgi6and2fokqess5tojy2u	670	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	670	5	533	533	CD
work_dbbvwgi6and2fokqess5tojy2u	670	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	670	7	542	542	CD
work_dbbvwgi6and2fokqess5tojy2u	670	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	671	1	52	52	CD
work_dbbvwgi6and2fokqess5tojy2u	671	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	672	1	Lehman	Lehman	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	2	AL	AL	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	672	4	Nakatsu	Nakatsu	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	5	Y	Y	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	672	7	Ching	Ching	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	8	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	672	10	Bronson	Bronson	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	11	RT	RT	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	672	13	Oakey	Oakey	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	14	RJ	RJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	672	16	Keiper	Keiper	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	17	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	672	18	Hrynko	Hrynko	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	19	N	N	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	20	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	672	21	Finger	Finger	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	22	JN	JN	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	23	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	672	24	Durham	Durham	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	25	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	672	26	Pierre	Pierre	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	27	D	D	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	28	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	672	29	Horton	Horton	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	30	DB	DB	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	31	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	672	32	Newton	Newton	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	33	JM	JM	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	34	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	672	35	Lyon	Lyon	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	36	MF	MF	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	37	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	672	38	Brilliant	brilliant	JJ
work_dbbvwgi6and2fokqess5tojy2u	672	39	MH	MH	NNP
work_dbbvwgi6and2fokqess5tojy2u	672	40	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	673	1	A	a	DT
work_dbbvwgi6and2fokqess5tojy2u	673	2	very	very	RB
work_dbbvwgi6and2fokqess5tojy2u	673	3	large	large	JJ
work_dbbvwgi6and2fokqess5tojy2u	673	4	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	673	5	with	with	IN
work_dbbvwgi6and2fokqess5tojy2u	673	6	diverse	diverse	JJ
work_dbbvwgi6and2fokqess5tojy2u	673	7	functional	functional	JJ
work_dbbvwgi6and2fokqess5tojy2u	673	8	motifs	motif	NNS
work_dbbvwgi6and2fokqess5tojy2u	673	9	is	be	VBZ
work_dbbvwgi6and2fokqess5tojy2u	673	10	deficient	deficient	JJ
work_dbbvwgi6and2fokqess5tojy2u	673	11	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	673	12	rjs	rjs	NNP
work_dbbvwgi6and2fokqess5tojy2u	673	13	(	(	-LRB-
work_dbbvwgi6and2fokqess5tojy2u	673	14	runty	runty	NNP
work_dbbvwgi6and2fokqess5tojy2u	673	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	673	16	jerky	jerky	NNP
work_dbbvwgi6and2fokqess5tojy2u	673	17	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	673	18	sterile	sterile	JJ
work_dbbvwgi6and2fokqess5tojy2u	673	19	)	)	-RRB-
work_dbbvwgi6and2fokqess5tojy2u	673	20	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	673	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	674	1	Proc	Proc	NNP
work_dbbvwgi6and2fokqess5tojy2u	674	2	Natl	Natl	NNP
work_dbbvwgi6and2fokqess5tojy2u	674	3	Acad	Acad	NNP
work_dbbvwgi6and2fokqess5tojy2u	674	4	Sci	Sci	NNP
work_dbbvwgi6and2fokqess5tojy2u	674	5	U	U	NNP
work_dbbvwgi6and2fokqess5tojy2u	674	6	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	674	7	A.	a.	NN
work_dbbvwgi6and2fokqess5tojy2u	675	1	1998	1998	CD
work_dbbvwgi6and2fokqess5tojy2u	675	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	675	3	95	95	CD
work_dbbvwgi6and2fokqess5tojy2u	675	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	675	5	9436	9436	CD
work_dbbvwgi6and2fokqess5tojy2u	675	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	675	7	9441	9441	CD
work_dbbvwgi6and2fokqess5tojy2u	675	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	676	1	53	53	CD
work_dbbvwgi6and2fokqess5tojy2u	676	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	677	1	Yue	Yue	NNP
work_dbbvwgi6and2fokqess5tojy2u	677	2	Z	Z	NNP
work_dbbvwgi6and2fokqess5tojy2u	677	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	677	4	Horton	Horton	NNP
work_dbbvwgi6and2fokqess5tojy2u	677	5	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	677	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	677	7	Bravin	Bravin	NNP
work_dbbvwgi6and2fokqess5tojy2u	677	8	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	677	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	677	10	DeJager	DeJager	NNP
work_dbbvwgi6and2fokqess5tojy2u	677	11	PL	PL	NNP
work_dbbvwgi6and2fokqess5tojy2u	677	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	677	13	Selimi	Selimi	NNP
work_dbbvwgi6and2fokqess5tojy2u	677	14	F	F	NNP
work_dbbvwgi6and2fokqess5tojy2u	677	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	677	16	Heintz	Heintz	NNP
work_dbbvwgi6and2fokqess5tojy2u	677	17	N.	N.	NNP
work_dbbvwgi6and2fokqess5tojy2u	677	18	A	a	DT
work_dbbvwgi6and2fokqess5tojy2u	677	19	novel	novel	JJ
work_dbbvwgi6and2fokqess5tojy2u	677	20	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	677	21	complex	complex	NN
work_dbbvwgi6and2fokqess5tojy2u	677	22	linking	link	VBG
work_dbbvwgi6and2fokqess5tojy2u	677	23	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	677	24	δ2	δ2	NNP
work_dbbvwgi6and2fokqess5tojy2u	677	25	glutamate	glutamate	NNP
work_dbbvwgi6and2fokqess5tojy2u	677	26	receptor	receptor	NN
work_dbbvwgi6and2fokqess5tojy2u	677	27	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	677	28	autophagy	autophagy	NN
work_dbbvwgi6and2fokqess5tojy2u	677	29	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	677	30	Implications	implication	NNS
work_dbbvwgi6and2fokqess5tojy2u	677	31	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	677	32	neurodegeneration	neurodegeneration	NN
work_dbbvwgi6and2fokqess5tojy2u	677	33	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	677	34	lurcher	lurcher	NN
work_dbbvwgi6and2fokqess5tojy2u	677	35	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	677	36	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	678	1	Neuron	neuron	UH
work_dbbvwgi6and2fokqess5tojy2u	678	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	679	1	2002	2002	CD
work_dbbvwgi6and2fokqess5tojy2u	679	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	679	3	35	35	CD
work_dbbvwgi6and2fokqess5tojy2u	679	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	679	5	921	921	CD
work_dbbvwgi6and2fokqess5tojy2u	679	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	679	7	933	933	CD
work_dbbvwgi6and2fokqess5tojy2u	679	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	680	1	54	54	CD
work_dbbvwgi6and2fokqess5tojy2u	680	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	681	1	Selimi	Selimi	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	2	F	F	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	681	4	Lohof	Lohof	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	5	AM	AM	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	681	7	Heitz	Heitz	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	8	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	681	10	Lalouette	Lalouette	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	11	A	A	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	681	13	Jarvis	Jarvis	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	14	CI	CI	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	681	16	Bailly	Bailly	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	17	Y	Y	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	681	19	Mariani	Mariani	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	20	J.	J.	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	21	Lurcher	Lurcher	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	22	GRID2-induced	GRID2-induced	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	23	death	death	NN
work_dbbvwgi6and2fokqess5tojy2u	681	24	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	681	25	depolarization	depolarization	NN
work_dbbvwgi6and2fokqess5tojy2u	681	26	can	can	MD
work_dbbvwgi6and2fokqess5tojy2u	681	27	Be	be	VB
work_dbbvwgi6and2fokqess5tojy2u	681	28	dissociated	dissociate	VBN
work_dbbvwgi6and2fokqess5tojy2u	681	29	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	681	30	cerebellar	cerebellar	JJ
work_dbbvwgi6and2fokqess5tojy2u	681	31	Purkinje	Purkinje	NNP
work_dbbvwgi6and2fokqess5tojy2u	681	32	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	681	33	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	682	1	Neuron	neuron	UH
work_dbbvwgi6and2fokqess5tojy2u	682	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	683	1	2003	2003	CD
work_dbbvwgi6and2fokqess5tojy2u	683	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	683	3	37	37	CD
work_dbbvwgi6and2fokqess5tojy2u	683	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	683	5	813	813	CD
work_dbbvwgi6and2fokqess5tojy2u	683	6	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	683	7	819	819	CD
work_dbbvwgi6and2fokqess5tojy2u	683	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	684	1	55	55	CD
work_dbbvwgi6and2fokqess5tojy2u	684	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	685	1	Chakrabarti	Chakrabarti	NNP
work_dbbvwgi6and2fokqess5tojy2u	685	2	L	L	NNP
work_dbbvwgi6and2fokqess5tojy2u	685	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	685	4	Eng	Eng	NNP
work_dbbvwgi6and2fokqess5tojy2u	685	5	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	685	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	685	7	Ivanov	Ivanov	NNP
work_dbbvwgi6and2fokqess5tojy2u	685	8	N	N	NNP
work_dbbvwgi6and2fokqess5tojy2u	685	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	685	10	Garden	Garden	NNP
work_dbbvwgi6and2fokqess5tojy2u	685	11	GA	GA	NNP
work_dbbvwgi6and2fokqess5tojy2u	685	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	685	13	La	La	NNP
work_dbbvwgi6and2fokqess5tojy2u	685	14	Spada	Spada	NNP
work_dbbvwgi6and2fokqess5tojy2u	685	15	AR	AR	NNP
work_dbbvwgi6and2fokqess5tojy2u	685	16	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	686	1	Autophagy	Autophagy	NNP
work_dbbvwgi6and2fokqess5tojy2u	686	2	activation	activation	NN
work_dbbvwgi6and2fokqess5tojy2u	686	3	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	686	4	enhanced	enhanced	JJ
work_dbbvwgi6and2fokqess5tojy2u	686	5	mitophagy	mitophagy	NN
work_dbbvwgi6and2fokqess5tojy2u	686	6	characterize	characterize	VB
work_dbbvwgi6and2fokqess5tojy2u	686	7	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	686	8	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	686	9	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	686	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	686	11	pcd	pcd	NN
work_dbbvwgi6and2fokqess5tojy2u	686	12	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	686	13	prior	prior	RB
work_dbbvwgi6and2fokqess5tojy2u	686	14	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	686	15	neuronal	neuronal	JJ
work_dbbvwgi6and2fokqess5tojy2u	686	16	death	death	NN
work_dbbvwgi6and2fokqess5tojy2u	686	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	687	1	Mol	Mol	NNP
work_dbbvwgi6and2fokqess5tojy2u	687	2	Brain	Brain	NNP
work_dbbvwgi6and2fokqess5tojy2u	687	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	688	1	2009	2009	CD
work_dbbvwgi6and2fokqess5tojy2u	688	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	688	3	2	2	CD
work_dbbvwgi6and2fokqess5tojy2u	688	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	688	5	24	24	CD
work_dbbvwgi6and2fokqess5tojy2u	688	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	689	1	56	56	CD
work_dbbvwgi6and2fokqess5tojy2u	689	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	690	1	Nishiyama	Nishiyama	NNP
work_dbbvwgi6and2fokqess5tojy2u	690	2	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	690	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	690	4	Miura	Miura	NNP
work_dbbvwgi6and2fokqess5tojy2u	690	5	E	E	NNP
work_dbbvwgi6and2fokqess5tojy2u	690	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	690	7	Mizushima	Mizushima	NNP
work_dbbvwgi6and2fokqess5tojy2u	690	8	N	N	NNP
work_dbbvwgi6and2fokqess5tojy2u	690	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	690	10	Watanabe	Watanabe	NNP
work_dbbvwgi6and2fokqess5tojy2u	690	11	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	690	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	690	13	Yuzaki	Yuzaki	NNP
work_dbbvwgi6and2fokqess5tojy2u	690	14	M.	M.	NNP
work_dbbvwgi6and2fokqess5tojy2u	690	15	Aberrant	Aberrant	NNP
work_dbbvwgi6and2fokqess5tojy2u	690	16	membranes	membrane	NNS
work_dbbvwgi6and2fokqess5tojy2u	690	17	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	690	18	double	double	JJ
work_dbbvwgi6and2fokqess5tojy2u	690	19	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	690	20	membrane	membrane	NN
work_dbbvwgi6and2fokqess5tojy2u	690	21	structures	structure	NNS
work_dbbvwgi6and2fokqess5tojy2u	690	22	accumulate	accumulate	VBP
work_dbbvwgi6and2fokqess5tojy2u	690	23	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	690	24	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	690	25	axons	axon	NNS
work_dbbvwgi6and2fokqess5tojy2u	690	26	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	690	27	Atg5-null	atg5-null	DT
work_dbbvwgi6and2fokqess5tojy2u	690	28	Purkinje	purkinje	JJ
work_dbbvwgi6and2fokqess5tojy2u	690	29	cells	cell	NNS
work_dbbvwgi6and2fokqess5tojy2u	690	30	before	before	IN
work_dbbvwgi6and2fokqess5tojy2u	690	31	neuronal	neuronal	JJ
work_dbbvwgi6and2fokqess5tojy2u	690	32	death	death	NN
work_dbbvwgi6and2fokqess5tojy2u	690	33	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	691	1	Autophagy	Autophagy	NNP
work_dbbvwgi6and2fokqess5tojy2u	691	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	692	1	2007	2007	CD
work_dbbvwgi6and2fokqess5tojy2u	692	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	692	3	3	3	CD
work_dbbvwgi6and2fokqess5tojy2u	692	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	692	5	591	591	CD
work_dbbvwgi6and2fokqess5tojy2u	692	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	692	7	596	596	CD
work_dbbvwgi6and2fokqess5tojy2u	692	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	693	1	57	57	CD
work_dbbvwgi6and2fokqess5tojy2u	693	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	694	1	Komatsu	Komatsu	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	2	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	694	4	Wang	Wang	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	5	QJ	QJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	694	7	Holstein	Holstein	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	8	GR	GR	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	694	10	Friedrich	Friedrich	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	11	VL	VL	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	694	13	Iwata	Iwata	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	14	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	694	16	Kominami	Kominami	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	17	E	E	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	694	19	Chait	Chait	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	20	BT	BT	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	694	22	Tanaka	Tanaka	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	23	K	K	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	694	25	Yue	Yue	NNP
work_dbbvwgi6and2fokqess5tojy2u	694	26	Z.	Z.	NNP
work_dbbvwgi6and2fokqess5tojy2u	695	1	Essential	essential	JJ
work_dbbvwgi6and2fokqess5tojy2u	695	2	role	role	NN
work_dbbvwgi6and2fokqess5tojy2u	695	3	for	for	IN
work_dbbvwgi6and2fokqess5tojy2u	695	4	autophagy	autophagy	NN
work_dbbvwgi6and2fokqess5tojy2u	695	5	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	695	6	Atg7	Atg7	NNP
work_dbbvwgi6and2fokqess5tojy2u	695	7	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	695	8	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	695	9	maintenance	maintenance	NN
work_dbbvwgi6and2fokqess5tojy2u	695	10	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	695	11	axonal	axonal	JJ
work_dbbvwgi6and2fokqess5tojy2u	695	12	homeostasis	homeostasis	NN
work_dbbvwgi6and2fokqess5tojy2u	695	13	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	695	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	695	15	prevention	prevention	NN
work_dbbvwgi6and2fokqess5tojy2u	695	16	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	695	17	axonal	axonal	JJ
work_dbbvwgi6and2fokqess5tojy2u	695	18	degeneration	degeneration	NN
work_dbbvwgi6and2fokqess5tojy2u	695	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	696	1	Proc	Proc	NNP
work_dbbvwgi6and2fokqess5tojy2u	696	2	Natl	Natl	NNP
work_dbbvwgi6and2fokqess5tojy2u	696	3	Acad	Acad	NNP
work_dbbvwgi6and2fokqess5tojy2u	696	4	Sci	Sci	NNP
work_dbbvwgi6and2fokqess5tojy2u	696	5	U	U	NNP
work_dbbvwgi6and2fokqess5tojy2u	696	6	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	696	7	A.	a.	NN
work_dbbvwgi6and2fokqess5tojy2u	697	1	2007	2007	CD
work_dbbvwgi6and2fokqess5tojy2u	697	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	697	3	104	104	CD
work_dbbvwgi6and2fokqess5tojy2u	697	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	697	5	14489	14489	CD
work_dbbvwgi6and2fokqess5tojy2u	697	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	697	7	14494	14494	CD
work_dbbvwgi6and2fokqess5tojy2u	697	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	698	1	58	58	CD
work_dbbvwgi6and2fokqess5tojy2u	698	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	699	1	Imai	Imai	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	2	Y	Y	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	699	4	Kobayashi	Kobayashi	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	5	Y	Y	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	6	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	699	7	Inoshita	Inoshita	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	8	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	9	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	699	10	Meng	Meng	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	11	H	H	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	12	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	699	13	Arano	Arano	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	14	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	699	16	Uemura	Uemura	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	17	K	K	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	699	19	Asano	Asano	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	20	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	21	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	699	22	Yoshimi	Yoshimi	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	23	K	K	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	24	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	699	25	Zhang	Zhang	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	26	CL	CL	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	27	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	699	28	Matsumoto	Matsumoto	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	29	G	G	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	30	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	699	31	Ohtsuka	Ohtsuka	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	32	T	T	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	33	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	699	34	Kageyama	Kageyama	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	35	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	36	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	699	37	Kiyonari	Kiyonari	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	38	H	H	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	39	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	699	40	et	et	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	41	al	al	NNP
work_dbbvwgi6and2fokqess5tojy2u	699	42	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	700	1	The	the	DT
work_dbbvwgi6and2fokqess5tojy2u	700	2	Parkinson	Parkinson	NNP
work_dbbvwgi6and2fokqess5tojy2u	700	3	’s	’s	POS
work_dbbvwgi6and2fokqess5tojy2u	700	4	Disease	Disease	NNP
work_dbbvwgi6and2fokqess5tojy2u	700	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	700	6	Associated	Associated	NNP
work_dbbvwgi6and2fokqess5tojy2u	700	7	Protein	Protein	NNP
work_dbbvwgi6and2fokqess5tojy2u	700	8	Kinase	Kinase	NNP
work_dbbvwgi6and2fokqess5tojy2u	700	9	LRRK2	lrrk2	NN
work_dbbvwgi6and2fokqess5tojy2u	700	10	Modulates	modulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	700	11	Notch	Notch	NNP
work_dbbvwgi6and2fokqess5tojy2u	700	12	Signaling	signal	VBG
work_dbbvwgi6and2fokqess5tojy2u	700	13	through	through	IN
work_dbbvwgi6and2fokqess5tojy2u	700	14	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	700	15	Endosomal	Endosomal	NNP
work_dbbvwgi6and2fokqess5tojy2u	700	16	Pathway	Pathway	NNP
work_dbbvwgi6and2fokqess5tojy2u	700	17	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	701	1	PLoS	PLoS	NNP
work_dbbvwgi6and2fokqess5tojy2u	701	2	Genet	Genet	NNP
work_dbbvwgi6and2fokqess5tojy2u	701	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	702	1	2015	2015	CD
work_dbbvwgi6and2fokqess5tojy2u	702	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	702	3	11	11	CD
work_dbbvwgi6and2fokqess5tojy2u	702	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	702	5	e1005503	e1005503	NN
work_dbbvwgi6and2fokqess5tojy2u	702	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	703	1	Oncotarget56106www.impactjournals.com/oncotarget	oncotarget56106www.impactjournals.com/oncotarget	ADD
work_dbbvwgi6and2fokqess5tojy2u	703	2	59	59	CD
work_dbbvwgi6and2fokqess5tojy2u	703	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	704	1	Romero	Romero	NNP
work_dbbvwgi6and2fokqess5tojy2u	704	2	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	704	3	Granados	Granados	NNP
work_dbbvwgi6and2fokqess5tojy2u	704	4	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	704	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	704	6	Fontán	Fontán	NNP
work_dbbvwgi6and2fokqess5tojy2u	704	7	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	704	8	Lozano	Lozano	NNP
work_dbbvwgi6and2fokqess5tojy2u	704	9	Á	Á	NNP
work_dbbvwgi6and2fokqess5tojy2u	704	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	704	11	Aguilar	Aguilar	NNP
work_dbbvwgi6and2fokqess5tojy2u	704	12	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	704	13	Montilla	Montilla	NNP
work_dbbvwgi6and2fokqess5tojy2u	704	14	FJ	FJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	704	15	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	704	16	Carrión	Carrión	NNP
work_dbbvwgi6and2fokqess5tojy2u	704	17	ÁM	ÁM	NNP
work_dbbvwgi6and2fokqess5tojy2u	704	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	705	1	Postnatal	postnatal	JJ
work_dbbvwgi6and2fokqess5tojy2u	705	2	proteasome	proteasome	NN
work_dbbvwgi6and2fokqess5tojy2u	705	3	inhibition	inhibition	NN
work_dbbvwgi6and2fokqess5tojy2u	705	4	induces	induce	VBZ
work_dbbvwgi6and2fokqess5tojy2u	705	5	neurodegeneration	neurodegeneration	NN
work_dbbvwgi6and2fokqess5tojy2u	705	6	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	705	7	cognitive	cognitive	JJ
work_dbbvwgi6and2fokqess5tojy2u	705	8	deficiencies	deficiency	NNS
work_dbbvwgi6and2fokqess5tojy2u	705	9	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	705	10	adult	adult	NN
work_dbbvwgi6and2fokqess5tojy2u	705	11	mice	mouse	NNS
work_dbbvwgi6and2fokqess5tojy2u	705	12	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	705	13	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	705	14	new	new	JJ
work_dbbvwgi6and2fokqess5tojy2u	705	15	model	model	NN
work_dbbvwgi6and2fokqess5tojy2u	705	16	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	705	17	neurodevelopment	neurodevelopment	NNP
work_dbbvwgi6and2fokqess5tojy2u	705	18	syndrome	syndrome	NNP
work_dbbvwgi6and2fokqess5tojy2u	705	19	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	706	1	PLoS	PLoS	:
work_dbbvwgi6and2fokqess5tojy2u	706	2	One	one	CD
work_dbbvwgi6and2fokqess5tojy2u	706	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	707	1	2011	2011	CD
work_dbbvwgi6and2fokqess5tojy2u	707	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	707	3	6	6	CD
work_dbbvwgi6and2fokqess5tojy2u	707	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	707	5	e28927	e28927	NN
work_dbbvwgi6and2fokqess5tojy2u	707	6	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	708	1	60	60	CD
work_dbbvwgi6and2fokqess5tojy2u	708	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	709	1	Suárez	Suárez	NNP
work_dbbvwgi6and2fokqess5tojy2u	709	2	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	709	3	Pereira	Pereira	NNP
work_dbbvwgi6and2fokqess5tojy2u	709	4	I	I	NNP
work_dbbvwgi6and2fokqess5tojy2u	709	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	709	6	Canals	Canals	NNP
work_dbbvwgi6and2fokqess5tojy2u	709	7	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	709	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	709	9	Carrión	Carrión	NNP
work_dbbvwgi6and2fokqess5tojy2u	709	10	AM	am	NN
work_dbbvwgi6and2fokqess5tojy2u	709	11	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	710	1	Adult	adult	JJ
work_dbbvwgi6and2fokqess5tojy2u	710	2	newborn	newborn	JJ
work_dbbvwgi6and2fokqess5tojy2u	710	3	neurons	neuron	NNS
work_dbbvwgi6and2fokqess5tojy2u	710	4	are	be	VBP
work_dbbvwgi6and2fokqess5tojy2u	710	5	involved	involve	VBN
work_dbbvwgi6and2fokqess5tojy2u	710	6	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	710	7	learning	learn	VBG
work_dbbvwgi6and2fokqess5tojy2u	710	8	acquisition	acquisition	NN
work_dbbvwgi6and2fokqess5tojy2u	710	9	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	710	10	long-	long-	JJ
work_dbbvwgi6and2fokqess5tojy2u	710	11	term	term	NN
work_dbbvwgi6and2fokqess5tojy2u	710	12	memory	memory	NN
work_dbbvwgi6and2fokqess5tojy2u	710	13	formation	formation	NN
work_dbbvwgi6and2fokqess5tojy2u	710	14	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	710	15	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	710	16	distinct	distinct	JJ
work_dbbvwgi6and2fokqess5tojy2u	710	17	demands	demand	NNS
work_dbbvwgi6and2fokqess5tojy2u	710	18	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	710	19	temporal	temporal	JJ
work_dbbvwgi6and2fokqess5tojy2u	710	20	neurogenesis	neurogenesis	NN
work_dbbvwgi6and2fokqess5tojy2u	710	21	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	710	22	different	different	JJ
work_dbbvwgi6and2fokqess5tojy2u	710	23	cognitive	cognitive	JJ
work_dbbvwgi6and2fokqess5tojy2u	710	24	tasks	task	NNS
work_dbbvwgi6and2fokqess5tojy2u	710	25	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	711	1	Hippocampus	Hippocampus	NNP
work_dbbvwgi6and2fokqess5tojy2u	711	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	712	1	2015	2015	CD
work_dbbvwgi6and2fokqess5tojy2u	712	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	712	3	25	25	CD
work_dbbvwgi6and2fokqess5tojy2u	712	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	712	5	51	51	CD
work_dbbvwgi6and2fokqess5tojy2u	712	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	712	7	61	61	CD
work_dbbvwgi6and2fokqess5tojy2u	712	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	713	1	61	61	CD
work_dbbvwgi6and2fokqess5tojy2u	713	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	714	1	Ruiz	Ruiz	NNP
work_dbbvwgi6and2fokqess5tojy2u	714	2	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	714	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	714	4	Tabares	Tabares	NNP
work_dbbvwgi6and2fokqess5tojy2u	714	5	L.	L.	NNP
work_dbbvwgi6and2fokqess5tojy2u	714	6	Neurotransmitter	Neurotransmitter	NNP
work_dbbvwgi6and2fokqess5tojy2u	714	7	release	release	NN
work_dbbvwgi6and2fokqess5tojy2u	714	8	in	in	IN
work_dbbvwgi6and2fokqess5tojy2u	714	9	motor	motor	NN
work_dbbvwgi6and2fokqess5tojy2u	714	10	nerve	nerve	NN
work_dbbvwgi6and2fokqess5tojy2u	714	11	terminals	terminal	NNS
work_dbbvwgi6and2fokqess5tojy2u	714	12	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	714	13	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	714	14	mouse	mouse	NN
work_dbbvwgi6and2fokqess5tojy2u	714	15	model	model	NN
work_dbbvwgi6and2fokqess5tojy2u	714	16	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	714	17	mild	mild	JJ
work_dbbvwgi6and2fokqess5tojy2u	714	18	spinal	spinal	JJ
work_dbbvwgi6and2fokqess5tojy2u	714	19	muscular	muscular	JJ
work_dbbvwgi6and2fokqess5tojy2u	714	20	atrophy	atrophy	NN
work_dbbvwgi6and2fokqess5tojy2u	714	21	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	715	1	J	J	NNP
work_dbbvwgi6and2fokqess5tojy2u	715	2	Anat	Anat	NNP
work_dbbvwgi6and2fokqess5tojy2u	715	3	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	716	1	2014	2014	CD
work_dbbvwgi6and2fokqess5tojy2u	716	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	716	3	224	224	CD
work_dbbvwgi6and2fokqess5tojy2u	716	4	:	:	SYM
work_dbbvwgi6and2fokqess5tojy2u	716	5	74	74	CD
work_dbbvwgi6and2fokqess5tojy2u	716	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	716	7	84	84	CD
work_dbbvwgi6and2fokqess5tojy2u	716	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	717	1	62	62	CD
work_dbbvwgi6and2fokqess5tojy2u	717	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	718	1	Rosa	Rosa	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	2	JL	JL	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	3	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	718	4	Casaroli	Casaroli	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	5	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	718	6	Marano	Marano	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	7	RP	RP	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	8	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	718	9	Buckler	Buckler	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	10	AJ	AJ	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	11	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	718	12	Vilaro	Vilaro	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	13	S	S	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	14	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	718	15	Barbacid	Barbacid	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	16	M.	M.	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	17	p619	p619	NN
work_dbbvwgi6and2fokqess5tojy2u	718	18	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	718	19	a	a	DT
work_dbbvwgi6and2fokqess5tojy2u	718	20	giant	giant	JJ
work_dbbvwgi6and2fokqess5tojy2u	718	21	protein	protein	NN
work_dbbvwgi6and2fokqess5tojy2u	718	22	related	relate	VBN
work_dbbvwgi6and2fokqess5tojy2u	718	23	to	to	IN
work_dbbvwgi6and2fokqess5tojy2u	718	24	the	the	DT
work_dbbvwgi6and2fokqess5tojy2u	718	25	chromosome	chromosome	NN
work_dbbvwgi6and2fokqess5tojy2u	718	26	condensation	condensation	NN
work_dbbvwgi6and2fokqess5tojy2u	718	27	regulator	regulator	NN
work_dbbvwgi6and2fokqess5tojy2u	718	28	RCC1	RCC1	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	29	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	718	30	stimulates	stimulate	VBZ
work_dbbvwgi6and2fokqess5tojy2u	718	31	guanine	guanine	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	32	nucleotide	nucleotide	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	33	exchange	exchange	NN
work_dbbvwgi6and2fokqess5tojy2u	718	34	on	on	IN
work_dbbvwgi6and2fokqess5tojy2u	718	35	ARF1	ARF1	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	36	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	718	37	Rab	Rab	NNP
work_dbbvwgi6and2fokqess5tojy2u	718	38	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	718	39	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	719	1	EMBO	EMBO	NNP
work_dbbvwgi6and2fokqess5tojy2u	719	2	J.	J.	NNP
work_dbbvwgi6and2fokqess5tojy2u	720	1	1996	1996	CD
work_dbbvwgi6and2fokqess5tojy2u	720	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	720	3	15	15	CD
work_dbbvwgi6and2fokqess5tojy2u	720	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	720	5	4262	4262	CD
work_dbbvwgi6and2fokqess5tojy2u	720	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	720	7	4273	4273	CD
work_dbbvwgi6and2fokqess5tojy2u	720	8	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	721	1	63	63	CD
work_dbbvwgi6and2fokqess5tojy2u	721	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	722	1	Cubillos	Cubillos	NNP
work_dbbvwgi6and2fokqess5tojy2u	722	2	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	722	3	Rojas	Rojas	NNP
work_dbbvwgi6and2fokqess5tojy2u	722	4	M	M	NNP
work_dbbvwgi6and2fokqess5tojy2u	722	5	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	722	6	Amair	Amair	NNP
work_dbbvwgi6and2fokqess5tojy2u	722	7	-	-	HYPH
work_dbbvwgi6and2fokqess5tojy2u	722	8	Pinedo	Pinedo	NNP
work_dbbvwgi6and2fokqess5tojy2u	722	9	F	F	NNP
work_dbbvwgi6and2fokqess5tojy2u	722	10	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	722	11	Tato	Tato	NNP
work_dbbvwgi6and2fokqess5tojy2u	722	12	I	I	NNP
work_dbbvwgi6and2fokqess5tojy2u	722	13	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	722	14	Bartrons	Bartrons	NNPS
work_dbbvwgi6and2fokqess5tojy2u	722	15	R	R	NNP
work_dbbvwgi6and2fokqess5tojy2u	722	16	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	722	17	Ventura	Ventura	NNP
work_dbbvwgi6and2fokqess5tojy2u	722	18	F	F	NNP
work_dbbvwgi6and2fokqess5tojy2u	722	19	,	,	,
work_dbbvwgi6and2fokqess5tojy2u	722	20	Rosa	Rosa	NNP
work_dbbvwgi6and2fokqess5tojy2u	722	21	JL	JL	NNP
work_dbbvwgi6and2fokqess5tojy2u	722	22	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	723	1	Simultaneous	simultaneous	JJ
work_dbbvwgi6and2fokqess5tojy2u	723	2	electrophoretic	electrophoretic	JJ
work_dbbvwgi6and2fokqess5tojy2u	723	3	analysis	analysis	NN
work_dbbvwgi6and2fokqess5tojy2u	723	4	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	723	5	proteins	protein	NNS
work_dbbvwgi6and2fokqess5tojy2u	723	6	of	of	IN
work_dbbvwgi6and2fokqess5tojy2u	723	7	very	very	RB
work_dbbvwgi6and2fokqess5tojy2u	723	8	high	high	JJ
work_dbbvwgi6and2fokqess5tojy2u	723	9	and	and	CC
work_dbbvwgi6and2fokqess5tojy2u	723	10	low	low	JJ
work_dbbvwgi6and2fokqess5tojy2u	723	11	molecular	molecular	JJ
work_dbbvwgi6and2fokqess5tojy2u	723	12	mass	mass	NN
work_dbbvwgi6and2fokqess5tojy2u	723	13	using	use	VBG
work_dbbvwgi6and2fokqess5tojy2u	723	14	Tris-	Tris-	VBN
work_dbbvwgi6and2fokqess5tojy2u	723	15	acetate	acetate	JJ
work_dbbvwgi6and2fokqess5tojy2u	723	16	polyacrylamide	polyacrylamide	NN
work_dbbvwgi6and2fokqess5tojy2u	723	17	gels	gel	NNS
work_dbbvwgi6and2fokqess5tojy2u	723	18	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	724	1	Electrophoresis	electrophoresis	NN
work_dbbvwgi6and2fokqess5tojy2u	724	2	.	.	.
work_dbbvwgi6and2fokqess5tojy2u	725	1	2010	2010	CD
work_dbbvwgi6and2fokqess5tojy2u	725	2	;	;	:
work_dbbvwgi6and2fokqess5tojy2u	725	3	31	31	CD
work_dbbvwgi6and2fokqess5tojy2u	725	4	:	:	:
work_dbbvwgi6and2fokqess5tojy2u	725	5	1318	1318	CD
work_dbbvwgi6and2fokqess5tojy2u	725	6	-	-	SYM
work_dbbvwgi6and2fokqess5tojy2u	725	7	1321	1321	CD
work_dbbvwgi6and2fokqess5tojy2u	725	8	.	.	.