id author title date pages extension mime words sentences flesch summary cache txt work_zskerdjlwnfyrp7uacsy3vi5yi Sung Kyun Park Arsenic exposure is associated with diminished insulin sensitivity in non-diabetic Amish adults 2016.0 7 .pdf application/pdf 5004 593 60 Arsenic exposure is associated with diminished insulin sensitivity in non-diabetic Amish adults No significant associations were found between urinary total arsenic and β-cell function measures. Copyright © 2015 John Wiley & Sons, Ltd. Keywords arsenic; β-cell function; insulin sensitivity; oral glucose tolerance test This is a preliminary study of the association between urinary arsenic and glucose homeostasis measures, conducted in the Amish Family Diabetes Study (AFDS), a Urinary total arsenic was significantly and inversely associated with all insulin sensitivity indices with adjustment remained significant for two of the three OGTT-based insulin sensitivity measures; an IQR increase in urinary total arsenic (6.24 μg/L) was significantly, inversely associated This is the first epidemiologic study to examine arsenic exposure and OGTT-based measures of insulin sensitivity We did not observe significant associations of urinary total arsenic with any measures of β-cell function. associations between arsenic metabolism and OGTTbased measures of insulin sensitivity and β-cell function. ./cache/work_zskerdjlwnfyrp7uacsy3vi5yi.pdf ./txt/work_zskerdjlwnfyrp7uacsy3vi5yi.txt