id author title date pages extension mime words sentences flesch summary cache txt work_ya36l2miezdmvlweal3zer73si Caroline G.P. Roberts Variants in Scavenger Receptor Class B Type I Gene Are Associated with HDL Cholesterol Levels in Younger Women 2007.0 7 .pdf application/pdf 5335 540 68 Variants in Scavenger Receptor Class B Type I Gene Are Associated with HDL Cholesterol Levels in Younger Women SCARB1 SNPs influence HDL-C levels in women, particularly type I ( SCARB1 ) receptor gene have been previously associated with lipid levels, especially in women, with some studies reporting the association to be stronger in the presence reported gender-specific association and modification effect of estrogen on lipid levels according to SCARB1 variants, we explored the relationship between SCARBI single nucleotide polymorphisms (SNPs) and lipid levels in an Amish population to assess sex and age differences. Gender-specific associations have been reported between some of the SCARB1 variants and lipid levels, an However, they did report significant estrogen interaction with the rs5888 SNP on HDL-C levels, greater than 50 years of age, these two SNPs were not associated with HDL-C levels. Mean HDL-C levels (SE) according to SCARB1 SNP genotype in women ≥50 and <50 years of age ./cache/work_ya36l2miezdmvlweal3zer73si.pdf ./txt/work_ya36l2miezdmvlweal3zer73si.txt