id author title date pages extension mime words sentences flesch summary cache txt work_y7jerywg7vcjpjcrmy6swfadcq Fabrizio Marinelli Insights into the mechanism of the Na+/Ca2+ exchanger from atomistic molecular dynamics simulations 2012.0 1 .pdf application/pdf 916 104 53 Insights into the mechanism of the Na+/Ca2+ exchanger from atomistic molecular dynamics simulations molecular mechanism of function of SSSF proteins. molecular modeling constrained by experimentally determined intramolecular distances and template restraints derived from the tenhelix core of the vSGLT crystal structure [2]. [3] resulted in an ensemble of helix bundle structures. external loop (eL) 9 of PutP upon sodium and/or l-proline binding. Mitochondrial carrier structure and diseases To date eleven disorders are known to be caused by defects of mitochondrial carriers, a family of proteins that shuttle a variety of metabolites revealed the existence in mitochondrial carriers of a substrate-binding mutations of the mitochondrial carriers. Palmieri, C.L. Pierri, FEBS Lett. E-mail: fabrizio.marinelli@biophys.mpg.de molecular modeling to investigate the occupancy and specificity of the ion binding sites in NCX_Mj, and the microscopic mechanism by which Na+ and Ca2+ are exchanged across the membrane. [3] T.M. Kang, D.W. Hilgemann, Nature 427 (2004) 544–548. http://dx.doi.org/10.1016/j.bbabio.2012.06.105 http://dx.doi.org/10.1016/j.bbabio.2012.06.105 http://dx.doi.org/10.1016/j.bbabio.2012.06.105 ./cache/work_y7jerywg7vcjpjcrmy6swfadcq.pdf ./txt/work_y7jerywg7vcjpjcrmy6swfadcq.txt