id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_xwvo2mgt2zds3a4cgwo4ad6snq	D. S. Gerhard	Identification of a recent recombination event within the human beta-globin gene cluster	1984.0	5	.pdf	application/pdf	5109	767	77	ABSTRACT In a detailed study of inheritance of DNA sequence polymorphism in a large reference pedigree, an individual was identified with an apparent genetic recombination haplotypes of relevant individuals within this pedigree suggested that the meiotic crossing-over event is likely to have occurred within a 19.8-kilobase-pair region of the fglobin gene At present, however, most genetic markers are distributed at such great distances along a mammalian chromosome that precise delineation of the site of a crossover is quite difficult. analysis is the ,3globin gene cluster (HBBC) of human chromosome 11. individual with one chromosome that appears to be a product of a recombination within the l3-globin gene region itself. the data: (i) a recombination within the P3-globin gene region, the + f-globin haplotype had undergone an obligate crossover within the region of lip carrying the HBBC. f3-globin gene region except the 3' BamHI site and at D11S12	./cache/work_xwvo2mgt2zds3a4cgwo4ad6snq.pdf	./txt/work_xwvo2mgt2zds3a4cgwo4ad6snq.txt