id author title date pages extension mime words sentences flesch summary cache txt work_xqpna25fy5g2nojorn2tmsyr24 Lillian B. Brown Assessment of sex-specific genetic and environmental effects on bone mineral density 2004.0 9 .pdf application/pdf 6803 541 62 Although it is widely accepted that genes contribute significantly to the variation in bone mineral density (BMD), the nature genetic effects influencing variation in BMD contribute to these differences is not known. variation in BMD into genetic and environmental effects common to both sexes and to men and women separately. accounting for covariate effects, the heritability of BMD ranged from 0.63 to 0.72 in men and 0.80 to 0.87 in women. The residual environmental variance in BMD at the spine, but not hip, was significantly higher in men than in women significant differences between men and women in the magnitude of the genetic variance in BMD, nor did the genetic for sex-specific genetic effects, suggesting that many of the genes influencing variation in BMD should be detectable in both & 2004 Wiley-Liss, Inc. Key words: sex; bone mineral density; genetics; variance; interaction; heritability sex-specific genetic effects on BMD. ./cache/work_xqpna25fy5g2nojorn2tmsyr24.pdf ./txt/work_xqpna25fy5g2nojorn2tmsyr24.txt