id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_v6iuaa6upvhbdf5pxng7knj72m	A. Duffy	Pre-pubertal bipolar disorder: origins and current status of the controversy	2020.0	10	.pdf	application/pdf	8223	651	53	risk for onset of bipolar disorder spans late adolescence and early adulthood. of a pre-pubertal form of bipolar disorder manifesting in early childhood created substantial debate. of children at high familial risk did not support the proposed pre-pubertal bipolar phenotype; but rather provided of the controversy surrounding the diagnosis of bipolar disorder in pre-adolescent children. mood episodes of diagnosed bipolar disorder in highrisk offspring were predominantly depressive (not manic) Longitudinal high-risk studies have not only been helpful in characterizing the onset and early course of bipolar disorder, but also in characterizing early childhood in children and adolescents, ICD-11 states that the diagnosis of bipolar disorder requires the presence of mania very young children with comorbid ADHD and associated problems in social and academic functioning represented a pre-pubertal form of bipolar disorder. Longitudinal prospective studies of children at confirmed familial high-risk of developing bipolar disorder 	./cache/work_v6iuaa6upvhbdf5pxng7knj72m.pdf	./txt/work_v6iuaa6upvhbdf5pxng7knj72m.txt