id author title date pages extension mime words sentences flesch summary cache txt work_tnsybizppragzngalc6zgacdie Christopher R. D'Adamo The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations 2016.0 11 .pdf application/pdf 6393 726 65 Alpha-carotene · Carotenoids · Genome-wide association study · CAPN2 · CAPN8 · PRKCE · The aim of this study was to identify genetic associations with serum α-carotene concentrations using the genome-wide association study (GWAS) approach. Results: Genome-wide significant associations with α-carotene concentrations were observed for loci on Although observational studies have consistently associated eating of carotenoidcontaining fruits and vegetables with lower risk of a variety of chronic diseases, interventions with carotenoid-rich diets and supplementation have not shown consistent health data from the National Health and Nutrition Examination Surveys revealed an inverse association between serum α-carotene concentrations and the risk of all-cause mortality as well The goal of this study was to identify novel genetic associations with serum α-carotene Manhattan plot for the genome-wide association study of serum α-carotene concentrations in the There was no evidence of an association between this locus and α-carotene concentrations in our study population (lead SNP: rs6564851, p = 0.28). ./cache/work_tnsybizppragzngalc6zgacdie.pdf ./txt/work_tnsybizppragzngalc6zgacdie.txt