id author title date pages extension mime words sentences flesch summary cache txt work_tahtnbrprve4hnkjgroa5eqydu L. M. 't Hart Lack of association between gene variants in the ALMS1 gene and Type 2 diabetes mellitus 2003.0 2 .pdf application/pdf 1681 220 72 Association studies were carried out with Type 2 diabetic patients (n=188) and age-matched normoglycaemic subjects was carried out to test associations with other diabetes related parameters like BMI, glucose and insulin concentrations. disease-associated gene variants are found more frequently in for Type 2 diabetic patients and associating co-morbidities. Type 2 diabetes, obesity and insulin resistance. our studies to the gene variants at positions Asp2674, Arg2828 We have also reconstructed haplotype combinations of the different gene variants This report describes association studies with gene variants in the coding region of the ALMS1 gene in Type 2 diabetes. The absence of significant associations suggest that the variants observed in our studies are not major factors in the pathogenesis of Type 2 diabetes mellitus or obesity. ALMS1 gene are not associated with Type 2 diabetes, BMI or other diabetes related parameters in a population based study Type 2 diabetes has been studied in this population ./cache/work_tahtnbrprve4hnkjgroa5eqydu.pdf ./txt/work_tahtnbrprve4hnkjgroa5eqydu.txt