id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_rouuffdcnnclxitdwwzdylajue	Danny Ben-Avraham	The GH receptor exon 3 deletion is a marker of male-specific exceptional longevity associated with increased GH sensitivity and taller stature	2017.0	9	.pdf	application/pdf	9455	1188	70	Peter Durda,6 Bing Liu,7 Sandy Ott,8 Danielle Gutman,9 Lital Sharvit,9 Robert Kaplan,10 Because a GH receptor exon 3 deletion (d3-GHR) appears to modulate GH sensitivity in humans, we hypothesized that this polymorphism could play a analysis of males in all cohorts resulted in a significant positive trend with age (26% increase; P = 0.007), suggesting sexual dimorphism for GH action in longevity. variant is a common genetic polymorphism that modulates GH responsiveness throughout the life span and positively affects male longevity. the d3-GHR deletion allele and longevity among the cohorts studied. homozygote GHR deletion polymorphism increased in males in all cohorts, suggesting gender specificity. Prevalence of d3-GHR homozygotes in relation to age groups in: (A) Ashkenazi Jew (AJ) (female and male of Cohen, Control of aging and longevity by IGF-I signaling. P. Bougnères, The exon-3 deletion of the growth hormone receptor (GHR) gene still has a	./cache/work_rouuffdcnnclxitdwwzdylajue.pdf	./txt/work_rouuffdcnnclxitdwwzdylajue.txt