id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_rfwaq4vdsnafroaa3pwflf5vuu	E. I. Ginns	A genome-wide search for chromosomal loci linked to mental health wellness in relatives at high risk for bipolar affective disorder among the Old Order Amish	1998.0	6	.pdf	application/pdf	6888	1099	70	evidence supports a significant genetic component in the susceptibility to develop BPAD. study, the unaffected, mentally healthy individuals in these families also were followed, many for a period of years past the age gene(s) modifying the relative risk for affective disorder is unknown (2) we relied exclusively on model-free linkage analyses. Model-free linkage analyses were conducted by using the two-point affected sib pair analysis program Because there were a few sibships with incomplete marker information, marker allele frequencies were estimated from the entire Old Order Amish family linkage analyses using SIBPAL and GH-PLUS (24) were performed by using mental health wellness as the linkage phenotype Order Amish families susceptibility alleles for BPAD probably mentally healthy individuals who share marker alleles that should protective alleles, these individuals do not manifest BPAD. individuals inherit disease susceptibility alleles but do not manifest the phenotype because of the simultaneous presence of alleles could affect the clinical manifestations of BPAD in the Old	./cache/work_rfwaq4vdsnafroaa3pwflf5vuu.pdf	./txt/work_rfwaq4vdsnafroaa3pwflf5vuu.txt