id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_qfrgkzpihrbcvmgrhtpljp3rbu	Shafali S. Jeste	Developmental disorders	2015.0	3	.pdf	application/pdf	1305	100	45	University of California, Los Angeles (UCLA) Semel Institute of Neuroscience and Human Behavior, David Geffen School of Medicine, Los When a child receives a diagnosis of a neurodevelopmental disorder, the first questions posed by advances in genetics, animal models, mechanismdriven biomarker development, and targeted intervention design have illuminated the path toward themes that are common across this group of disorders that can provide insight into disease mechanisms and targeted treatments. genetically and phenotypically distinct disorders that there is convergence on molecular and neurodevelopmental pathways, despite extreme genetic specific molecular, cellular, and circuit-level impairments that lead to the core deficits of ASD, namely, After careful characterization of the mouse phenotype, rationally designed treatments for ASD can be intervention research in ASD and related developmental disorders. series of flexible, evidence-based strategies are tailored to the specific needs of a child). Health grant K23MH094517 (Jeste) and National Institute of Child Health and Human Development grant	./cache/work_qfrgkzpihrbcvmgrhtpljp3rbu.pdf	./txt/work_qfrgkzpihrbcvmgrhtpljp3rbu.txt