id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_qd5oxtscm5akjcukdlffphuzre	Vincent Chau	Preclinical Therapeutic Efficacy of a Novel Pharmacologic Inducer of Apoptosis in Malignant Peripheral Nerve Sheath Tumors	2013.0	13	.pdf	application/pdf	8767	1213	63	debilitating growths that can transform into malignant peripheral nerve sheath tumors (MPNST), a main cause of chemical compound that inhibits tumor cell growth. Moreover, Cpd21 can reduce MPNST burden in a mouse allograft model, underscoring the compound's potential E and F, dose-response curves of Cpd21 treatment on human MPNST cell lines, cells, compared with sMPNST and MPNST from cis-Nf1f/f;p53f/f mice. H, soft agar assay of Cpd21-treated (0.25, 0.5, 1, 2.5, or 5 mmol/L) sMPNST cells sMPNST cells were treated with DMSO, D, or with Cpd21 (0.25, 0.5, 1, 2.5, or 5 mmol/L) for 24 hours and RNA harvested for qRT-PCR for cyclins (B), cdks (C), or E, Western blot analysis for cyclin D1 in sMPNST cells that were treated with DMSO, D, or Cpd21 (0.25, 0.5, 1, and 2.5 mmol/L). We examined Cpd21-treated sMPNST cells for apoptosis by studies of dual LY294002 and Cpd21 treatment to MPNST cells	./cache/work_qd5oxtscm5akjcukdlffphuzre.pdf	./txt/work_qd5oxtscm5akjcukdlffphuzre.txt