id author title date pages extension mime words sentences flesch summary cache txt work_oylp4jtv55agnmivcvppcbe2xq Amish Asthana Molecular basis for cytokine biomarkers of complex 3D microtissue physiology in vitro 2016.0 42 .pdf application/pdf 10393 1128 56 time for a microtissue, with respect to meaningful assay results, biomarkers of threedimensionality that reliably predict CPR outcomes and are expressed early in culture are a musthave. Recently, many studies have shown that when cells are grown in a 3D culture their cytokine production of cytokines and survival and growth factors important for the cell. The pathway to cytokine upregulation: Ras/Raf/ERK signaling and transcription factors of hematopoietic cells by activated Raf genes has often been shown to result in the expression of NIH-3T3 cells expressing activated Raf have shown increased secretion of directly implicated in the expression of cytokines, mitogens and cell survival factors (see Table control and activation of the pathway is essential for production and regulation of the cytokines gel cultures [87] and in mammary tumor cell spheroids, where its activation was also responsible AP-1 activity leads to cytokine production, depending on the cell type (malignant versus ./cache/work_oylp4jtv55agnmivcvppcbe2xq.pdf ./txt/work_oylp4jtv55agnmivcvppcbe2xq.txt