id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_og2xsaoyxvfrnpzlal5q7itgge	Richa Saxena	Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge	2010.0	17	.pdf	application/pdf	8600	2367	78	Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, 17Cardiovascular Health Research Unit and Department of Medicine, University of Washington, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA. We identify variants at the GIPR locus associated with 2-h glucose level (rs10423928, β VPS13C), only ADCY5 was found to be associated with type 2 diabetes in collaborating studies (n have led to the discovery of genetic variation associated with fasting glucose levels in repeated our association analysis including fasting glucose as a covariate (Table 1 and Because GIP is involved in the insulin response specific to an oral glucose challenge, GIPR homozygous for the Gln354-encoding allele of this gene had lower fasting and post oralload C-peptide levels, suggesting a role for GIPR in insulin secretion20; this is in line with associated with 2-h glucose, in GIPR, VPS13C, ADCY5, GCKR and TCF7L2. are associated with fasting6 and 2-h glucose levels and with an increased risk of T2D,	./cache/work_og2xsaoyxvfrnpzlal5q7itgge.pdf	./txt/work_og2xsaoyxvfrnpzlal5q7itgge.txt