id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_o6te4dpdgbgzfbquukuy25xofe	Kevin A. Strauss	A population-based study of KCNH7 p.Arg394His and bipolar spectrum disorder	2014.0	12	.pdf	application/pdf	8631	960	56	prevalent bipolar spectrum disorder, identified 10 potentially pathogenic alleles by exome sequencing, tested association of these alleles with clinical diagnoses in the larger Amish Study of Major Affective Disorder expression, trafficking, assembly and localization of HERG3/Kv11.3 channels, but altered the steady-state voltage dependence and kinetics of activation in neuronal cells. neuronal HERG3/Kv11.3 potassium channels in the pathophysiology of bipolar spectrum disorder. promise as a means to identify individuals predisposed to psychiatric disease (5), but genetic studies of mental illness have thus ASMAD were used to test associations of exome variants with bipolar spectrum disorder (eighteen ASMAD samples were individuals from Families A and C and Among seven Amish individuals with bipolar spectrum disorder, we identified a total of 83 668 exome variants, 17 609 of which remained after filtering out However, a recent independent GWA study suggests an association between bipolar illness and a different KCNH7 variant in a	./cache/work_o6te4dpdgbgzfbquukuy25xofe.pdf	./txt/work_o6te4dpdgbgzfbquukuy25xofe.txt