id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_o4csbslwovcudlv5zqlh4j36ca	Cristopher V. Van Hout	Extent and distribution of linkage disequilibrium in the Old Order Amish	2009.0	5	.pdf	application/pdf	4719	425	71	the Old Order Amish (OOA) of Lancaster County Pennsylvania, a closed population derived from a modest number of International HapMap project (abbreviated CEU) using a high-density single nucleotide polymorphism (SNP) map. For example, the median absolute allele frequency dif ference for autosomal SNPs was 0.05, with an inter-quartile range of was at least 0.8 for 15 and 14% of SNP pairs in the OOA and CEU, respectively. HapMap CEU sample captured a substantial portion of the common variation in the OOA (�88%) at r2Z0.8. suggest that the OOA and CEU may share similar LD profiles for other common but untyped SNPs. Thus, in the context of the common variant-common disease hypothesis, genetic variants discovered in gene mapping studies in the OOA may OOA, Old Order Amish (n 5 60); CEU, US Utah residents from HapMap (n 5 60). OOA, Old Order Amish (n 5 60); CEU, US Utah residents from HapMap (n 5 60).	./cache/work_o4csbslwovcudlv5zqlh4j36ca.pdf	./txt/work_o4csbslwovcudlv5zqlh4j36ca.txt