id author title date pages extension mime words sentences flesch summary cache txt work_nk65msuaynbtrkqmmawg7wbcje Michelle M. Stein Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children 2016.0 11 .pdf application/pdf 8353 2113 78 Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children Amish and Hutterite children, measuring levels of allergens and endotoxins and assessing the microbiome composition of indoor dust samples. measure serum IgE levels, cytokine responses, and gene expression, and peripheralblood leukocytes were phenotyped with flow cytometry. Profound differences in the proportions, phenotypes, and functions of innate immune cells were also found between the two groups of children. a mouse model of experimental allergic asthma, the intranasal instillation of dust extracts from Amish but not Hutterite homes significantly inhibited airway hyperreactivity and eosinophilia. Innate Immunity and Asthma Risk in Amish and Hutterite Proportions of Peripheral-Blood Leukocytes and Cell-Surface–Marker Phenotypes in Amish and Hutterite Children. Our studies in Amish and Hutterite schoolchildren revealed marked differences in the prevalence of asthma despite similar genetic ancestries and lifestyles. Gene-Expression Profiles in Peripheral-Blood Leukocytes from Amish and Hutterite Children. ./cache/work_nk65msuaynbtrkqmmawg7wbcje.pdf ./txt/work_nk65msuaynbtrkqmmawg7wbcje.txt