id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_n5rzagndlnedrhwtvzoapoob7q	Y. Wang	Whole-genome association study identifies STK39 as a hypertension susceptibility gene	2008.0	6	.pdf	application/pdf	7301	963	68	Whole-genome association study identifies STK39 subjects and found strong association signals with common variants in a serine/threonine kinase gene, STK39. blood pressure � essential hypertension � genome-wide association study � genome-wide association (GWA) analysis in the Old Order Amish, 542 subjects of the Amish Family Diabetes Study (AFDS) (Table 1) (4). of Amish subjects to determine the effect size of this association, we Whole genome association scan results for SBP in 542 AFDS subjects. (A) Exonic structure, association between STK39 SNPs and SBP/DBP. Significance levels of association to SBP are shown along with genetic models. the same direction as in our Amish studies, the STK39 association HAPI, GenNet, and Hutterites), STK39 SNPs were more significantly associated with SBP under the recessive model than under subjects), and their association with BP vanished when the genotypes of another SNP from either bin were included as covariates associated with hypertension in the DGI subjects (P � .05; data not	./cache/work_n5rzagndlnedrhwtvzoapoob7q.pdf	./txt/work_n5rzagndlnedrhwtvzoapoob7q.txt