id author title date pages extension mime words sentences flesch summary cache txt work_mqtzdqegkbepfdxfxvzgqcybza Eleftheria Zeggini Variation Within the Gene Encoding the Upstream Stimulatory Factor 1 Does Not Influence Susceptibility to Type 2 Diabetes in Samples From Populations With Replicated Evidence of Linkage to Chromosome 1q 2006.0 8 .pdf application/pdf 7837 678 63 These data exclude USF1 as a major contributor to type 2 diabetes susceptibility and the basis for frequently sampled intravenous glucose tolerance test; LD, linkage disequilibrium; MAF, minor allele frequency; SNP, single nucleotide polymorphism; USF1 variation on type 2 diabetes risk and related metabolic traits, making explicit use of populations and samples selected because of their prior evidence for linkage to case-control sample, analyzed using family-based association methods. 832 Pima samples include 570 type 2 diabetic subjects (diagnosed before age 1. Single-point case-control association analyses for the USF1 gene region. (for USF1, F11R, and ARHGAP30), the SNPs typed, and those associated with FCHL or triglycerides (Pajukanta et al. the case-control association P values for the four samples from European descent. SNPs (from rs4339888 to rs1556259) showed no association with type 2 diabetes in any of the populations studied Single SNP analyses for association with type 2 diabetes for all seven samples combined ./cache/work_mqtzdqegkbepfdxfxvzgqcybza.pdf ./txt/work_mqtzdqegkbepfdxfxvzgqcybza.txt