id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_lpformor4zczzejsqd2nnkh4au	Gretchen H. Roffler	SNP discovery in candidate adaptive genes using exon capture in a free-ranging alpine ungulate	2016.0	18	.pdf	application/pdf	11985	1364	57	We used targeted resequencing to identify SNP markers in 5321 candidate adaptive genes associated with known immunological, metabolic and growth functions in ovids and other ungulates. We selectively targeted 8161 exons in protein-coding and nearby 50 and 30 untranslated regions of chosen candidate genes. The bighorn sheep sequences used in the Dall's sheep (Ovis dalli dalli) exon capture aligned to 2350 genes on the oviAri3 genome with an average of 2 exons each. qPCR-based SNP chip to genotype 476 Dall's sheep from locations across their range and test for patterns of selection. natural selection on nine genes with immune and disease-regulating functions (e.g. Ovar-DRA, APC, BATF2, Keywords: candidate genes, exon capture, next-generation sequencing, Ovis dalli dalli, population genomics, SNP chip the fully sequenced genomes of model species (e.g. domestic sheep; Dalrymple et al. Table 3 SNP loci identified as potentially under selection for Dall's sheep using FST outlier and environmental correlation tests.	./cache/work_lpformor4zczzejsqd2nnkh4au.pdf	./txt/work_lpformor4zczzejsqd2nnkh4au.txt