id author title date pages extension mime words sentences flesch summary cache txt work_hitmdbq6vbcd3jhkivh5m6fa4m Swapan Kumar Das Polymorphisms in the Glucokinase-Associated, Dual-Specificity Phosphatase 12 (DUSP12) Gene Under Chromosome 1q21 Linkage Peak Are Associated With Type 2 Diabetes 2006.0 9 .pdf application/pdf 8914 693 64 unrelated nondiabetic Caucasian and 48 nondiabetic African-American subjects for linkage disequilibrium before selecting markers for typing in the full initial observation were typed first in pooled Caucasian samples, and differences between case and control frequencies �5% were confirmed in individual Among Caucasians, 19 variants were associated with type 2 diabetes (P � 0.05), Summary of SNPs typed in Caucasian individual samples for DUSP12 region frequencies and associated alleles differed from Caucasians (Fig. 2 and supplemental Table 4S). Table 2 shows the haplotypes from the STR at �8379 through SNP �10309, with only the common (minor allele frequency �0.1) variants To determine whether DUSP12 SNPs were associated with type 2 diabetes in other populations, we Chromosome 1q21-q23 is among the best-replicated regions of linkage to type 2 diabetes, with evidence for DUSP12 IS ASSOCIATED WITH TYPE 2 DIABETES DUSP12 IS ASSOCIATED WITH TYPE 2 DIABETES DUSP12 IS ASSOCIATED WITH TYPE 2 DIABETES DUSP12 IS ASSOCIATED WITH TYPE 2 DIABETES ./cache/work_hitmdbq6vbcd3jhkivh5m6fa4m.pdf ./txt/work_hitmdbq6vbcd3jhkivh5m6fa4m.txt