id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_gg7tymewnvc4nbetxlzb73uypm	Afif El-Khuffash	Efficacy of paracetamol on patent ductus arteriosus closure may be dose dependent: evidence from human and murine studies	2014.0	7	.pdf	application/pdf	6285	1632	79	use of paracetamol for PDA closure in preterm infants with myography was performed to study ductus tone and examine drug-induced changes in lumen diameter (d). isolated mouse ductus at term gestation, with complete closure of the vessel lumen at the highest concentrations studied Paracetamol also caused significant concentration-dependent constriction of the term ductus. did not have an ex vivo constricting effect on the preterm ductus, and vessels treated with paracetamol had insignificant In conclusion, the routine use of paracetamol for PDA closure in preterm infants cannot be recommended until randomized controlled trials of its efficacy are completed. of human ductus tissues, the response of the ex vivo term and preterm mouse DA to indomethacin and paracetamol was examined. Efficacy of paracetamol on patent ductus arteriosus closure may be dose dependent: evidence from human and murine studies Efficacy of paracetamol on patent ductus arteriosus closure may be dose dependent: evidence from human and murine studies	./cache/work_gg7tymewnvc4nbetxlzb73uypm.pdf	./txt/work_gg7tymewnvc4nbetxlzb73uypm.txt