id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_frjmlko6ona5jpfn3lsaztuzua	J Scott	Molecular genetics of common diseases	1987.0	3	.pdf	application/pdf	3778	550	64	Molecular genetics of common diseases Number ofgene loci implicated in polygenic disease problem as an example; table II lists genes that may be associated on the genetic variance in plasma cholesterol concentration-the cosegregation does exist a causal role for the gene in the disease is amyloid protein gene might be found to predispose to the disease. recently provided a candidate locus on chromosome 5 for a gene that Another risk factor for coronary heart disease is plasma fibrinogen Genetic polymorphism and susceptibility to disease Common alleles (variants at a single locus) or polymorphisms genetic polymorphisms that contribute to the common polygenic susceptibility to disease occurs at the apo-E locus.'5 The presence of Further examples of such polymorphisms associated with predisposition to polygenic disease have now been described. disequilibrium at the same locus) that are associated with disease Iflinked genes confer susceptibility to a disease this Apolipoprotein B-gene DNA polymorphisms	./cache/work_frjmlko6ona5jpfn3lsaztuzua.pdf	./txt/work_frjmlko6ona5jpfn3lsaztuzua.txt