id author title date pages extension mime words sentences flesch summary cache txt work_foeq2b7k7ret3k2xlad6575miu Yunhua L. Muller Functional Variants in MBL2 Are Associated With Type 2 Diabetes and Pre-Diabetes Traits in Pima Indians and the Old Order Amish 2010.0 6 .pdf application/pdf 6209 673 69 the diabetes risk allele glycine of Gly54Asp was associated with MBL2, this gene was investigated as a potential susceptibility gene for type 2 diabetes in Pima Indians. genotyped in the sample of 3,501 full-heritage Pima Indians for association analysis with type 2 diabetes (Table 1). To determine whether variants in MBL2 had a significant effect on diabetes in non–Native American populations, rs1800450 and rs11003125 were genotyped in an pairwise LD pattern of these 101 SNPs and their association with early-onset type 2 diabetes in Pima subjects who Fig. 3), was not associated with type 2 diabetes in Pima Associations of MBL2 tag SNPs with type 2 diabetes in Pima Indians Association of promoter rs1103125 and rs1800450 (Gly54Asp) with type 2 diabetes in Pima Indian, Amish, and DIAGRAM subjects Ordering the genotypic groups according to their association with serum MBL levels showed that subjects homozygous for both G and glycine alleles had a higher prevalence ./cache/work_foeq2b7k7ret3k2xlad6575miu.pdf ./txt/work_foeq2b7k7ret3k2xlad6575miu.txt