id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_fnmoisn5zngbtbqtzclpaas3ei	Robert P Jankov	Sodium nitrite augments lung S-nitrosylation and reverses chronic hypoxic pulmonary hypertension in juvenile rats	2018.0	10	.pdf	application/pdf	8360	995	58	Sodium nitrite augments lung S-nitrosylation and reverses chronic hypoxic pulmonary hypertension in juvenile rats Sodium nitrite augments lung S-nitrosylation and reverses chronic hypoxic have previously reported that therapy with inhaled NO (iNO) increased peroxynitrite-mediated nitration in the juvenile rat lung, Animals then received rescue therapy with daily subcutaneous NaNO2 (20 mg/kg), vehicle, or were continuously exposed to iNO both prevented and reversed chronic hypoxic PHT and increased lung NO and SNO contents to a far greater extent than Rescue treatment with NaNO2 increased lung NOx, SNO Chronic exposure to hypoxia or treatment with NaNO2 had no effect on total lung Rescue sodium nitrite increased lung nitric oxide oxidation (NOx), S-nitrosylated (SNO) proteins, and cGMP-PKG activity, without increasing nitration. subcutaneous injections of sodium nitrite (NaNO2) 20 mg/kg or 0.9% saline vehicle or were continuously exposed to 20 ppm inhaled nitric oxide (iNO). B: total lung SNO proteins, n � 6 animals per group.	./cache/work_fnmoisn5zngbtbqtzclpaas3ei.pdf	./txt/work_fnmoisn5zngbtbqtzclpaas3ei.txt