id author title date pages extension mime words sentences flesch summary cache txt work_evvtooqdnbfl5k3uaet64iwl3u Lisette Arnaud-Lopez Phosphodiesterase 8B Gene Variants Are Associated with Serum TSH Levels and Thyroid Function 2008.0 11 .pdf application/pdf 8677 911 68 By genotyping 362,129 SNPs in 4,300 Sardinians, we identified a strong association (p ¼ 1.3 3 10�11) between alleles of rs4704397 and circulating TSH levels; each additional In addition to association of TSH levels with SNPs in PDE8B, our genome scan provided evidence for association with Top SNPs Associated with TSH Levels from the GWA in SardiNIA For each marker, the �log10 of the p value resulting from an association test that evaluates its additive effect on the phenotype is plotted. (A) The top panel summarizes association between the SNPs and TSH levels in each individual (�log10 of the p value). SNP rs6885099 showed the strongest association with TSH levels in an initial analysis performed on a subset of Phosphodiesterase 8B Gene Variants Are Associated with Serum TSH Levels and Thyroid Function Association Analysis of Candidate Genes with TSH Levels ./cache/work_evvtooqdnbfl5k3uaet64iwl3u.pdf ./txt/work_evvtooqdnbfl5k3uaet64iwl3u.txt