id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_dwbxxnrckbfsth4j6gsq57v4o4	M. Fu	Polymorphism in the Calsequestrin 1 (CASQ1) Gene on Chromosome 1q21 Is Associated With Type 2 Diabetes in the Old Order Amish	2004.0	8	.pdf	application/pdf	8032	1327	75	SNPs within CASQ1 were genotyped in Amish subjects nucleotide polymorphisms (SNPs) in Amish type 2 diabetic cases and nondiabetic control subjects. further, we screened CASQ1 for mutations and determined whether the observed sequence variation was associated with type 2 diabetes and related traits in the Old Next, to examine the relationship between haplotype-tagging polymorphisms in CASQ1 and diabetes, we genotyped DNA from subjects with type 2 subjects in our Amish pedigrees, we tested for associations of SNP genotypes 3 flanking region showed borderline evidence for association to type 2 diabetes (P � 0.076 – 0.093). 2. Association of CASQ1 SNPs rs617698 and rs2275703 with glucose and insulin levels during a 3-h OGTT in nondiabetic individuals. The two SNPs associated with type 2 diabetes, rs617698 Sakul H, Wagner MJ, Burns DK, Shuldiner AR: Genome-wide and finemapping linkage studies of type 2 diabetes and glucose traits in the Old	./cache/work_dwbxxnrckbfsth4j6gsq57v4o4.pdf	./txt/work_dwbxxnrckbfsth4j6gsq57v4o4.txt