id author title date pages extension mime words sentences flesch summary cache txt work_dbstwym7nnga7hsg3aovt6665m Kevin A. Strauss Genetics, Medicine, and the Plain People 2009.0 26 .pdf application/pdf 16287 4434 77 Our studies with the Pennsylvania Plain communities show that population-specific genetic knowledge provides a powerful framework in which to prevent disease, reduce among Old Order communities were the subject of exceptional observational studies, collected in the 1978 landmark Medical Genetic serves Old Order Amish and Mennonite people of Pennsylvania and Maryland, who are the Plain populations ideal for early genetic mapping studies, which relied on large collections of Many mapping studies in Plain populations have identified disease genes in this way Further inspection of SNP allele frequencies shows that Amish and Mennonite populations are genetically dissimilar. Table 3 Thirty-seven Amish and 29 Mennonite disorders understood at the molecular level among demes of Pennsylvania, Table 4 Twenty-three genetic disorders mapped using SNP microarrays at the Clinic 1 This table lists a selection of genetic syndromes that cause developmental disorders in Amish and Mennonite and the genetic disorders of the Amish and Mennonite people of Pennsylvania. ./cache/work_dbstwym7nnga7hsg3aovt6665m.pdf ./txt/work_dbstwym7nnga7hsg3aovt6665m.txt