id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_chkdq54dxzawhmoxya53tmzpee	Amish Asthana	Microtissue size and hypoxia in HTS with 3D cultures	2012.0	8	.pdf	application/pdf	6429	850	57	microtissue size (spatial) and hypoxia (chemical) can be used in the formation of physiologically more relevant constructs (or not) for cell-based high-throughput screening (HTS) in drug discovery. might be incompetent if tested with a microtissue tumor model having a larger size, owing to drug testing by differentiating stem cells, a larger between microtissue size and gene expression Hypoxia controlled genes/proteins found upregulated in 3D/2D comparative studies. Abbreviations: IL, interleukin; CXCL2, Macrophage inflammatory protein 2; FTH1, Ferritin Heavy subunit; FTL, Ferritin Light subunit; HIG2, hypoxia-inducible gene 2 protein; ND, Not in terms of promoting stem cell growth, differentiation and development of complex physiologically relevant structures and functionality. effects of hypoxia on stem cell function, embryonic embryonic stem cells cultured at reduced oxygen Microtissue size and hypoxia in HTS with 3D cultures Microtissue size and hypoxia in HTS with 3D cultures Hypoxia and stem cell niches Hypoxia and stem cell niches	./cache/work_chkdq54dxzawhmoxya53tmzpee.pdf	./txt/work_chkdq54dxzawhmoxya53tmzpee.txt