id author title date pages extension mime words sentences flesch summary cache txt work_bl6owa5zuzbspj4klcbqfzrvia Anup K. Nair Complex Genetics of Type 2 Diabetes and Effect Size: What have We Learned from Isolated Populations? 2015.0 21 .pdf application/pdf 16945 1851 64 Genetic studies in large outbred populations have documented a complex, highly polygenic basis for type 2 diabetes Most of the variants currently known to be associated with T2D risk have been identified in large studies that The plethora of studies to identify DNA variation that affects risk of T2D in diverse populations worldwide has led us to a better ^^ A common (3% of the population) missense variant was identified in ABCC8 in Pima Indians that associated with a 2-fold increased risk for T2D. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese. A genome-wide association study in American Indians implicates DNER as a susceptibility locus for type 2 diabetes. ./cache/work_bl6owa5zuzbspj4klcbqfzrvia.pdf ./txt/work_bl6owa5zuzbspj4klcbqfzrvia.txt