id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_avwd5qf26jef3besfviblpinxm	Chad Garner	Linkage Analysis of a Complex Pedigree with Severe Bipolar Disorder, Using a Markov Chain Monte Carlo Method	2001.0	4	.pdf	application/pdf	2531	438	72	Linkage Analysis of a Complex Pedigree with Severe Bipolar Disorder, Recently developed algorithms permit nonparametric linkage analysis of large, complex pedigrees with multiple published genome-screen data from a Costa Rican kindred segregating for severe bipolar disorder. individuals (including 81 affected with BP) could be represented as a single, highly consanguineous 10-generation kindred, for linkage analyses, the family has been of linkage using large pedigrees, mapping studies of complex traits now mainly use less-powerful nuclear-family compute linkage statistics on highly complex pedigrees. Locations, Allele-Sharing Statistics, and P Values for Five Markers Locations, Allele-Sharing Statistics, and P Values for Five Markers the majority of affected individuals shared a marker haplotype in this region (Freimer et al. significance levels for all 25 markers tested on chromosome 18q in the current analysis; each of these markers showed allele-sharing statistics that were 11 SD Linkage Analysis of a Complex Pedigree with Severe Bipolar Disorder, Using a Markov Chain Monte Carlo Method	./cache/work_avwd5qf26jef3besfviblpinxm.pdf	./txt/work_avwd5qf26jef3besfviblpinxm.txt