id author title date pages extension mime words sentences flesch summary cache txt work_aaeorgrudjdtdks5nrrozuen5e Daphne Yau Central venous catheter-associated thrombosis in children with congenital hyperinsulinism 2019.0 5 .pdf application/pdf 3213 340 56 high concentrations of dextrose are often required through a central venous catheter (CVC) with consequent risk of We describe a series of six cases of CHI due to varying aetiologies from our centre requiring CVC for the management of hypoglycaemia, who developed thrombosis in association with CVC. incidence and risk factors for CVC-associated thrombosis, as well as the outcomes of enoxaparin prophylaxis. receiving enoxaparin prophylaxis, none developed thrombosis or bleeding complications. CHI severity may be a risk factor for thrombosis development. often requiring central venous catheter (CVC) insertion to of CVC-associated thrombosis in CHI patients, presented Table 1 Characteristics of CHI patients with and without thrombosis. Thrombosis was associated with a marginally higher proportion of patients with compound heterozygous and homozygous KATP mutations. The characteristics of the patients on enoxaparin prophylaxis were similar to those with thrombosis. infused via the CVC prior to thrombosis development, a ./cache/work_aaeorgrudjdtdks5nrrozuen5e.pdf ./txt/work_aaeorgrudjdtdks5nrrozuen5e.txt