id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_a4fufuwvkjfkbf2nfqvm7nnttu	Haiqing Shen	Genome-wide association study identifies genetic variants in GOT1 determining serum aspartate aminotransferase levels	2011.0	5	.pdf	application/pdf	4308	508	61	We carried out a genome-wide association study of serum aspartate aminotransferase (AST) activity in 866 Amish participants of the Heredity and Phenotype Intervention Heart Study and identified significant association of AST activity with a cluster of single serum AST levels by carrying out a genome-wide association study We carried out a GWAS of serum AST activity levels in 866 Amish carriers had serum AST activity levels that were approximately onehalf that of normal homozygotes, suggesting that the deletion resulted Serum AST activity levels are determined by both genetic and Figure 1 Genome-wide association analysis plot for serum AST levels in 866 Old Order Amish subjects. AST and ALT measurements were based on 10 GOT1 deletion carriers from HAPI Heart study. A mutation in GOT1 determines serum AST levels Genome-wide association study identifies genetic variants in GOT1 determining serum aspartate aminotransferase levels Genome-wide association study identifies genetic variants in GOT1 determining serum aspartate aminotransferase levels	./cache/work_a4fufuwvkjfkbf2nfqvm7nnttu.pdf	./txt/work_a4fufuwvkjfkbf2nfqvm7nnttu.txt