id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_7xwporzchfgyxe7ufkbpxiexvu	M Gill	Linkage analysis of manic depression in an Irish family using H-ras 1 and INS DNA markers	1988.0	2	.pdf	application/pdf	1564	302	77	Manic depression (bipolar affective disorder) is one of the unipolar major depression by the occurrence of manic Egeland et all have shown linkage between the manic depressive phenotype in one North American pedigree and markers and the manic depressive phenotype, assuming depression and the chromosome 11 markers H-ras 1 and manic depression in this family are at other, as yet manic depressive gene loci in this and other pedigrees. tDepression and Manic Depression Research Unit, FIGURE Pedigree of family showing age, H-ras 1 alleles TABLE Lod scores calculated between the two marker loci, H-ras I and INS, and the manic depression phenotype, for disorders linked to DNA markers on chromosome 11. genetic evidence for heterogeneity in manic depression. Two separate primary amniotic fluid cell cultures at Noted were the following craniofacial anomalies: high and narrow forehead, long philtrum, The deletion was found in 24% (6/25) of cultured cells	./cache/work_7xwporzchfgyxe7ufkbpxiexvu.pdf	./txt/work_7xwporzchfgyxe7ufkbpxiexvu.txt